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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs10486715
log Bayes Factor = 0.636577
Chromosome 7   position 41,478,608  (GRCh37) Explore rs10486715 on Ensembl!
Variant rs10486715 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10-E14 Diabetes mellitus
0.713 0.287 0.000
E14 Unspecified diabetes mellitus
0.708 0.292 0.000
E14.9 Without complications
0.704 0.296 0.000
E11 Non-insulin-dependent diabetes mellitus
0.699 0.301 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.696 0.304 0.000
Chapter VI Diseases of the nervous system
0.692 0.308 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.689 0.311 0.000
# Top node
0.689 0.311 0.000
Chapter XX External causes of morbidity and mortality
0.676 0.324 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.660 0.340 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.657 0.343 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.646 0.354 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.646 0.354 0.000
G40-G47 Episodic and paroxysmal disorders
0.642 0.358 0.000
E11.2 With renal complications
0.641 0.359 0.000
Chapter VIII Diseases of the ear and mastoid process
0.639 0.361 0.000
M45-M49 Spondylopathies
0.637 0.363 0.000
G57 Mononeuropathies of lower limb
0.635 0.365 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.635 0.365 0.000
M47 Spondylosis
0.633 0.367 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.623 0.377 0.000
S60-S69 Injuries to the wrist and hand
0.618 0.382 0.000
E11.3 With ophthalmic complications
0.607 0.393 0.000
G57.6 Lesion of plantar nerve
0.604 0.396 0.000
E11.4 With neurological complications
0.595 0.405 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.592 0.407 0.000
W20-W49 Exposure to inanimate mechanical forces
0.592 0.408 0.000
M47.8 Other spondylosis
0.592 0.408 0.000
Y52 Agents primarily affecting the cardiovascular system
0.591 0.409 0.000
M47.9 Spondylosis, unspecified
0.591 0.409 0.000
M50-M54 Other dorsopathies
0.588 0.412 0.000
T66-T78 Other and unspecified effects of external causes
0.585 0.415 0.000
G43 Migraine
0.582 0.418 0.000
E10 Insulin-dependent diabetes mellitus
0.576 0.424 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.575 0.424 0.000
M54 Dorsalgia
0.575 0.425 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.573 0.427 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.569 0.431 0.000
E14.3 With ophthalmic complications
0.563 0.437 0.000
G40 Epilepsy
0.561 0.439 0.000
Chapter V Mental and behavioural disorders
0.560 0.440 0.000
T90 Sequelae of injuries of head
0.560 0.440 0.000
G82 Paraplegia and tetraplegia
0.560 0.440 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.560 0.440 0.000
M54.5 Low back pain
0.558 0.442 0.000
E20-E35 Disorders of other endocrine glands
0.558 0.442 0.000
Y00-Y09 Assault
0.557 0.443 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.557 0.443 0.000
G90-G99 Other disorders of the nervous system
0.556 0.444 0.000
H80-H83 Diseases of inner ear
0.554 0.446 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.552 0.448 0.000
M47.2 Other spondylosis with radiculopathy
0.551 0.449 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.550 0.450 0.000
T93 Sequelae of injuries of lower limb
0.547 0.453 0.000
S10-S19 Injuries to the neck
0.547 0.453 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.546 0.454 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.545 0.455 0.000
G57.8 Other mononeuropathies of lower limb
0.542 0.458 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.541 0.459 0.000
S20-S29 Injuries to the thorax
0.538 0.462 0.000
S70-S79 Injuries to the hip and thigh
0.533 0.466 0.000
F30-F39 Mood [affective] disorders
0.533 0.467 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.531 0.469 0.000
V40-V49 Car occupant injured in transport accident
0.531 0.469 0.000
M46 Other inflammatory spondylopathies
0.530 0.470 0.000
M54.56 Low back pain (Lumbar region)
0.529 0.471 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.528 0.472 0.000
G43.9 Migraine, unspecified
0.528 0.472 0.000
E11.6 With other specified complications
0.527 0.473 0.000
W50-W64 Exposure to animate mechanical forces
0.527 0.473 0.000
Y57 Other and unspecified drugs and medicaments
0.527 0.473 0.000
G70-G73 Diseases of myoneural junction and muscle
0.526 0.474 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.526 0.474 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.525 0.475 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.525 0.475 0.000
H65-H75 Diseases of middle ear and mastoid
0.524 0.476 0.000
S80-S89 Injuries to the knee and lower leg
0.523 0.476 0.000
S50-S59 Injuries to the elbow and forearm
0.523 0.477 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.523 0.477 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.523 0.477 0.000
S90-S99 Injuries to the ankle and foot
0.522 0.478 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.522 0.478 0.000
T79-T79 Certain early complications of trauma
0.520 0.480 0.000
E11.9 Without complications
0.519 0.481 0.000
G58 Other mononeuropathies
0.518 0.482 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.515 0.485 0.000
M60-M63 Disorders of muscles
0.515 0.485 0.000
G30-G32 Other degenerative diseases of the nervous system
0.514 0.486 0.000
S40-S49 Injuries to the shoulder and upper arm
0.513 0.487 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.512 0.488 0.000
E12 Malnutrition-related diabetes mellitus
0.511 0.489 0.000
V10-V19 Pedal cyclist injured in transport accident
0.511 0.489 0.000
E11.5 With peripheral circulatory complications
0.510 0.490 0.000
H90-H95 Other disorders of ear
0.510 0.490 0.000
S60 Superficial injury of wrist and hand
0.509 0.491 0.000
E14.8 With unspecified complications
0.508 0.492 0.000
E14.7 With multiple complications
0.508 0.492 0.000
E14.6 With other specified complications
0.508 0.492 0.000
E14.5 With peripheral circulatory complications
0.508 0.492 0.000
E14.4 With neurological complications
0.508 0.492 0.000
E14.2 Withrenal complications
0.508 0.492 0.000
E14.1 With ketoacidosis
0.508 0.492 0.000
E14.0 With coma
0.508 0.492 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.508 0.492 0.000
G59.0 Diabetic mononeuropathy
0.505 0.495 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.505 0.495 0.000
T78 Adverse effects, not elsewhere classified
0.505 0.495 0.000
X50-X57 Overexertion, travel and privation
0.504 0.496 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.504 0.496 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.504 0.496 0.000
E11.8 With unspecified complications
0.501 0.499 0.000
E11.7 With multiple complications
0.501 0.499 0.000
E11.1 With ketoacidosis
0.501 0.499 0.000
E11.0 With coma
0.501 0.499 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.500 0.500 0.000
H81 Disorders of vestibular function
0.500 0.500 0.000
E40-E46 Malnutrition
0.500 0.500 0.000
T33-T35 Frostbite
0.499 0.501 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.499 0.501 0.000
T00-T07 Injuries involving multiple body regions
0.499 0.501 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.498 0.502 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.498 0.502 0.000
T39.1 4-Aminophenol derivatives
0.498 0.502 0.000
G82.2 Paraplegia, unspecified
0.496 0.504 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.496 0.504 0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)
0.495 0.505 0.000
T91 Sequelae of injuries of neck and trunk
0.495 0.505 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.494 0.506 0.000
E50-E64 Other nutritional deficiencies
0.494 0.506 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.494 0.506 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.492 0.508 0.000
G83 Other paralytic syndromes
0.492 0.508 0.000
T42.4 Benzodiazepines
0.492 0.508 0.000
X60-X84 Intentional self-harm
0.491 0.508 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.491 0.509 0.000
T31 Burns classified according to extent of body surface involved
0.489 0.511 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.489 0.511 0.000
G63.2 Diabetic polyneuropathy
0.488 0.512 0.000
E13 Other specified diabetes mellitus
0.487 0.513 0.000
W22 Striking against or struck by other objects
0.487 0.513 0.000
X20-X29 Contact with venomous animals and plants
0.487 0.513 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.486 0.514 0.000
Y35-Y36 Legal intervention and operations of war
0.484 0.515 0.000
Y10-Y34 Event of undetermined intent
0.484 0.515 0.000
X85-X99 Assault
0.484 0.515 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.484 0.515 0.000
X30-X39 Exposure to forces of nature
0.484 0.515 0.000
X10-X19 Contact with heat and hot substances
0.484 0.515 0.000
X00-X09 Exposure to smoke, fire and flames
0.484 0.515 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.484 0.515 0.000
W75-W84 Other accidental threats to breathing
0.484 0.515 0.000
W65-W74 Accidental drowning and submersion
0.484 0.515 0.000
V98-V99 Other and unspecified transport accidents
0.484 0.515 0.000
V95-V97 Air and space transport accidents
0.484 0.515 0.000
V90-V94 Water transport accidents
0.484 0.515 0.000
V70-V79 Bus occupant injured in transport accident
0.484 0.515 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.484 0.515 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.484 0.515 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.484 0.515 0.000
V01-V09 Pedestrian injured in transport accident
0.484 0.515 0.000
G41 Status epilepticus
0.484 0.516 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.482 0.518 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.479 0.521 0.000
S65 Injury of blood vessels at wrist and hand level
0.479 0.521 0.000
V20-V29 Motorcycle rider injured in transport accident
0.478 0.521 0.000
M86-M90 Other osteopathies
0.478 0.522 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.478 0.522 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.477 0.522 0.000
T98 Sequelae of other and unspecified effects of external causes
0.477 0.523 0.000
S68 Traumatic amputation of wrist and hand
0.476 0.524 0.000
E10.2 With renal complications
0.476 0.524 0.000
F32 Depressive episode
0.474 0.526 0.000
V80-V89 Other land transport accidents
0.474 0.526 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.474 0.526 0.000
S80 Superficial injury of lower leg
0.474 0.526 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.473 0.526 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.473 0.526 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.473 0.526 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.473 0.526 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.473 0.526 0.000
T36 Poisoning by systemic antibiotics
0.473 0.526 0.000
H65 Nonsuppurative otitis media
0.473 0.527 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.473 0.527 0.000
W20 Struck by thrown, projected or falling object
0.473 0.527 0.000
S70 Superficial injury of hip and thigh
0.472 0.527 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.473 0.527 0.000
Y04 Assault by bodily force
0.472 0.527 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.472 0.528 0.000
Chapter XXII Codes for special purposes
0.472 0.528 0.000
G52 Disorders of other cranial nerves
0.471 0.529 0.000
M54.3 Sciatica
0.471 0.529 0.000
W21 Striking against or struck by sports equipment
0.470 0.530 0.000
M54.6 Pain in thoracic spine
0.469 0.531 0.000
S69 Other and unspecified injuries of wrist and hand
0.469 0.531 0.000
M54.57 Low back pain (Lumbosacral region)
0.469 0.531 0.000
G54 Nerve root and plexus disorders
0.469 0.531 0.000
H60-H62 Diseases of external ear
0.469 0.531 0.000
M54.59 Low back pain (Site unspecified)
0.468 0.532 0.000
M00-M03 Infectious arthropathies
0.468 0.532 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.467 0.533 0.000
T23 Burn and corrosion of wrist and hand
0.466 0.534 0.000
T92 Sequelae of injuries of upper limb
0.466 0.534 0.000
M80-M85 Disorders of bone density and structure
0.464 0.536 0.000
T95 Sequelae of burns, corrosions and frostbite
0.463 0.536 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.463 0.536 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.463 0.536 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.463 0.536 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.462 0.538 0.000
Y40 Systemic antibiotics
0.461 0.539 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.460 0.540 0.000
M47.82 Other spondylosis (Cervical region)
0.460 0.540 0.000
M49 Spondylopathies in diseases classified elsewhere
0.457 0.543 0.000
M91-M94 Chondropathies
0.457 0.543 0.000
G56 Mononeuropathies of upper limb
0.457 0.543 0.000
G95 Other diseases of spinal cord
0.457 0.543 0.000
Y52.1 Calcium-channel blockers
0.456 0.544 0.000
G57.9 Mononeuropathy of lower limb, unspecified
0.455 0.545 0.000
G57.5 Tarsal tunnel syndrome
0.455 0.545 0.000
G57.4 Lesion of medial popliteal nerve
0.455 0.545 0.000
G57.3 Lesion of lateral popliteal nerve
0.455 0.545 0.000
G57.2 Lesion of femoral nerve
0.455 0.545 0.000
G57.1 Meralgia paraesthetica
0.455 0.545 0.000
G57.0 Lesion of sciatic nerve
0.455 0.545 0.000
Y59 Other and unspecified vaccines and biological substances
0.455 0.545 0.000
Y58 Bacterial vaccines
0.455 0.545 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.455 0.545 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.455 0.545 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.455 0.545 0.000
Y48 Anaesthetics and therapeutic gases
0.455 0.545 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.455 0.545 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.455 0.545 0.000
E10.4 With neurological complications
0.455 0.545 0.000
M47.1 Other spondylosis with myelopathy
0.454 0.546 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.454 0.546 0.000
S67 Crushing injury of wrist and hand
0.453 0.547 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.453 0.547 0.000
G43.1 Migraine with aura [classical migraine]
0.453 0.547 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.452 0.548 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.450 0.550 0.000
G80 Infantile cerebral palsy
0.450 0.550 0.000
F31 Bipolar affective disorder
0.450 0.550 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.448 0.552 0.000
G82.5 Tetraplegia, unspecified
0.447 0.553 0.000
G50 Disorders of trigeminal nerve
0.446 0.554 0.000
T93.9 Sequelae of unspecified injury of lower limb
0.446 0.554 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.444 0.556 0.000
Y85 Sequelae of transport accidents
0.444 0.556 0.000
Y57.9 Drug or medicament, unspecified
0.444 0.556 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.443 0.557 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.442 0.558 0.000
T90.4 Sequelae of injury of eye and orbit
0.442 0.558 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.441 0.559 0.000
M53 Other dorsopathies, not elsewhere classified
0.441 0.559 0.000
S60.9 Superficial injury of wrist and hand, unspecified
0.440 0.560 0.000
Q80-Q89 Other congenital malformations
0.439 0.561 0.000
W44 Foreign body entering into or through eye or natural orifice
0.438 0.561 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.438 0.562 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.438 0.562 0.000
M70-M79 Other soft tissue disorders
0.437 0.563 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.437 0.563 0.000
S40 Superficial injury of shoulder and upper arm
0.436 0.563 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.436 0.564 0.000
G40.9 Epilepsy, unspecified
0.436 0.564 0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.435 0.565 0.000
S61 Open wound of wrist and hand
0.435 0.565 0.000
G81 Hemiplegia
0.435 0.565 0.000
S66.8 Injury of other muscles and tendons at wrist and hand level
0.434 0.566 0.000
M54.1 Radiculopathy
0.434 0.566 0.000
T45.5 Anticoagulants
0.433 0.567 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.433 0.567 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.432 0.568 0.000
S52 Fracture of forearm
0.432 0.568 0.000
H81.0 Meniere's disease
0.432 0.568 0.000
E55 Vitamin D deficiency
0.431 0.569 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.431 0.569 0.000
M54.4 Lumbago with sciatica
0.430 0.569 0.000
F33 Recurrent depressive disorder
0.429 0.571 0.000
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)
0.429 0.571 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.428 0.572 0.000
G44 Other headache syndromes
0.428 0.572 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.428 0.572 0.000
S10 Superficial injury of neck
0.427 0.573 0.000
T31.0 Burns involving less than 10% of body surface
0.427 0.573 0.000
T58 Toxic effect of carbon monoxide
0.426 0.574 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.426 0.574 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.426 0.574 0.000
W25 Contact with sharp glass
0.425 0.575 0.000
M47.86 Other spondylosis (Lumbar region)
0.425 0.575 0.000
H65.3 Chronic mucoid otitis media
0.425 0.575 0.000
T25 Burn and corrosion of ankle and foot
0.425 0.575 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.425 0.575 0.000
T21 Burn and corrosion of trunk
0.425 0.575 0.000
T20 Burn and corrosion of head and neck
0.425 0.575 0.000
W49 Exposure to other and unspecified inanimate mechanical forces
0.425 0.575 0.000
W46 Contact with hypodermic needle
0.425 0.575 0.000
W45 Foreign body or object entering through skin
0.425 0.575 0.000
W43 Exposure to vibration
0.425 0.575 0.000
W42 Exposure to noise
0.425 0.575 0.000
W41 Exposure to high-pressure jet
0.425 0.575 0.000
W40 Explosion of other materials
0.425 0.575 0.000
W39 Discharge of firework
0.425 0.575 0.000
W38 Explosion and rupture of other specified pressurised devices
0.425 0.575 0.000
W37 Explosion and rupture of pressurised tyre, pipe or hose
0.425 0.575 0.000
W36 Explosion and rupture of gas cylinder
0.425 0.575 0.000
W35 Explosion and rupture of boiler
0.425 0.575 0.000
W34 Discharge from other and unspecified firearms
0.425 0.575 0.000
W33 Rifle, shotgun and larger firearm discharge
0.425 0.575 0.000
W32 Handgun discharge
0.425 0.575 0.000
W31 Contact with other and unspecified machinery
0.425 0.575 0.000
W30 Contact with agricultural machinery
0.425 0.575 0.000
W28 Contact with powered lawn mower
0.425 0.575 0.000
W27 Contact with nonpowered hand tool
0.425 0.575 0.000
W26 Contact with knife, sword or dagger
0.425 0.575 0.000
W24 Contact with lifting and transmission devices, not elsewhere classified
0.425 0.575 0.000
W23 Caught, crushed, jammed or pinched in or between objects
0.425 0.575 0.000
M45 Ankylosing spondylitis
0.425 0.575 0.000
M47.89 Other spondylosis (Site unspecified)
0.425 0.575 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.425 0.575 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.425 0.575 0.000
M47.84 Other spondylosis (Thoracic region)
0.425 0.575 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.425 0.575 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.425 0.575 0.000
E10.9 Without complications
0.424 0.576 0.000
S29 Other and unspecified injuries of thorax
0.424 0.576 0.000
E10.5 With peripheral circulatory complications
0.424 0.576 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.424 0.576 0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system
0.424 0.576 0.000
Y52.8 Antivaricose drugs, including sclerosing agents
0.424 0.576 0.000
Y52.7 Peripheral vasodilators
0.424 0.576 0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.424 0.576 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.424 0.576 0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action
0.424 0.576 0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)
0.423 0.576 0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)
0.423 0.576 0.000
M47.94 Spondylosis, unspecified (Thoracic region)
0.423 0.576 0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)
0.423 0.576 0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)
0.423 0.576 0.000
T22.0 Burn of unspecified degree of shoulder and upper limb, except wrist and hand
0.423 0.577 0.000
E28 Ovarian dysfunction
0.423 0.577 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.421 0.579 0.000
M62 Other disorders of muscle
0.421 0.579 0.000
W51 Striking against or bumped into by another person
0.421 0.579 0.000
T68 Hypothermia
0.420 0.579 0.000
G03 Meningitis due to other and unspecified causes
0.420 0.579 0.000
T45.0 Antiallergic and antiemetic drugs
0.420 0.580 0.000
T75 Effects of other external causes
0.419 0.580 0.000
T74 Maltreatment syndromes
0.419 0.580 0.000
T73 Effects of other deprivation
0.419 0.580 0.000
T70 Effects of air pressure and water pressure
0.419 0.580 0.000
T69 Other effects of reduced temperature
0.419 0.580 0.000
T67 Effects of heat and light
0.419 0.580 0.000
T71 Asphyxiation
0.419 0.580 0.000
T66 Unspecified effects of radiation
0.419 0.580 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.418 0.582 0.000
H81.1 Benign paroxysmal vertigo
0.418 0.582 0.000
G58.8 Other specified mononeuropathies
0.418 0.582 0.000
T78.2 Anaphylactic shock, unspecified
0.418 0.582 0.000
F80-F89 Disorders of psychological development
0.418 0.582 0.000
G43.8 Other migraine
0.417 0.582 0.000
G43.3 Complicated migraine
0.417 0.582 0.000
G43.2 Status migrainosus
0.417 0.582 0.000
G43.0 Migraine without aura [common migraine]
0.417 0.582 0.000
Q50-Q56 Congenital malformations of genital organs
0.417 0.583 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.417 0.583 0.000
G20-G26 Extrapyramidal and movement disorders
0.416 0.584 0.000
E29 Testicular dysfunction
0.414 0.586 0.000
M46.4 Discitis, unspecified
0.414 0.586 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.414 0.586 0.000
T90.5 Sequelae of intracranial injury
0.414 0.586 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.413 0.586 0.000
E10.8 With unspecified complications
0.413 0.587 0.000
E10.7 With multiple complications
0.413 0.587 0.000
E10.6 With other specified complications
0.413 0.587 0.000
E10.0 With coma
0.413 0.587 0.000
T32 Corrosions classified according to extent of body surface involved
0.413 0.587 0.000
T30 Burn and corrosion, body region unspecified
0.413 0.587 0.000
T29 Burns and corrosions of multiple body regions
0.413 0.587 0.000
M54.8 Other dorsalgia
0.412 0.587 0.000
M54.0 Panniculitis affecting regions of neck and back
0.412 0.587 0.000
T17 Foreign body in respiratory tract
0.412 0.587 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.412 0.588 0.000
Y45.1 Salicylates
0.412 0.588 0.000
Y49.2 Other and unspecified antidepressants
0.412 0.588 0.000
H69 Other disorders of Eustachian tube
0.412 0.588 0.000
H90 Conductive and sensorineural hearing loss
0.412 0.588 0.000
W22.9 Unspecified place
0.412 0.588 0.000
V49 Car occupant injured in other and unspecified transport accidents
0.411 0.589 0.000
G60 Hereditary and idiopathic neuropathy
0.411 0.589 0.000
G64 Other disorders of peripheral nervous system
0.411 0.589 0.000
H91 Other hearing loss
0.411 0.589 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.410 0.590 0.000
S80.9 Superficial injury of lower leg, unspecified
0.410 0.590 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.409 0.591 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.408 0.592 0.000
G59.8 Other mononeuropathies in diseases classified elsewhere
0.408 0.592 0.000
G70 Myasthenia gravis and other myoneural disorders
0.408 0.592 0.000
S19 Other and unspecified injuries of neck
0.408 0.592 0.000
S89 Other and unspecified injuries of lower leg
0.408 0.592 0.000
F99-F99 Unspecified mental disorder
0.407 0.593 0.000
E10.3 With ophthalmic complications
0.406 0.594 0.000
F32.9 Depressive episode, unspecified
0.406 0.594 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.405 0.595 0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level
0.405 0.595 0.000
E23 Hypofunction and other disorders of pituitary gland
0.405 0.595 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.404 0.596 0.000
G40.8 Other epilepsy
0.402 0.598 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.402 0.598 0.000
G40.5 Special epileptic syndromes
0.402 0.598 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.402 0.598 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.402 0.598 0.000
E16 Other disorders of pancreatic internal secretion
0.402 0.598 0.000
F30 Manic episode
0.402 0.598 0.000
M65-M68 Disorders of synovium and tendon
0.402 0.598 0.000
H93 Other disorders of ear, not elsewhere classified
0.402 0.598 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.401 0.598 0.000
F70-F79 Mental retardation
0.401 0.598 0.000
T90.8 Sequelae of other specified injuries of head
0.401 0.598 0.000
T90.3 Sequelae of injury of cranial nerves
0.401 0.598 0.000
T90.1 Sequelae of open wound of head
0.401 0.598 0.000
T90.0 Sequelae of superficial injury of head
0.401 0.598 0.000
G82.4 Spastic tetraplegia
0.401 0.598 0.000
G82.3 Flaccid tetraplegia
0.401 0.598 0.000
G82.1 Spastic paraplegia
0.401 0.598 0.000
G82.0 Flaccid paraplegia
0.401 0.598 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.401 0.599 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.401 0.599 0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.401 0.599 0.000
G00 Bacterial meningitis, not elsewhere classified
0.401 0.599 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.401 0.599 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.401 0.599 0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.401 0.599 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.401 0.599 0.000
D80-D89 Certain disorders involving the immune mechanism
0.401 0.599 0.000
G93 Other disorders of brain
0.401 0.599 0.000
V48 Car occupant injured in noncollision transport accident
0.401 0.599 0.000
M54.55 Low back pain (Thoracolumbar region)
0.400 0.600 0.000
M54.54 Low back pain-Thoracic
0.400 0.600 0.000
M54.53 Low back pain-Cervicothoracic
0.400 0.600 0.000
M54.52 Low back pain-Cervical
0.400 0.600 0.000
M54.51 Low back pain-Occipit-atl-axl
0.400 0.600 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.400 0.600 0.000
E34 Other endocrine disorders
0.400 0.600 0.000
E32 Diseases of thymus
0.400 0.600 0.000
E31 Polyglandular dysfunction
0.400 0.600 0.000
E30 Disorders of puberty, not elsewhere classified
0.400 0.600 0.000
E26 Hyperaldosteronism
0.400 0.600 0.000
E25 Adrenogenital disorders
0.400 0.600 0.000
E24 Cushing's syndrome
0.400 0.600 0.000
E22 Hyperfunction of pituitary gland
0.400 0.600 0.000
E20 Hypoparathyroidism
0.400 0.600 0.000
Y44 Agents primarily affecting blood constituents
0.400 0.600 0.000
Y09 Assault by unspecified means
0.400 0.600 0.000
Y08 Assault by other specified means
0.400 0.600 0.000
Y07 Other maltreatment syndromes
0.400 0.600 0.000
Y06 Neglect and abandonment
0.400 0.600 0.000
Y05 Sexual assault by bodily force
0.400 0.600 0.000
Y03 Assault by crashing of motor vehicle
0.400 0.600 0.000
Y02 Assault by pushing or placing victim before moving object
0.400 0.600 0.000
Y01 Assault by pushing from high place
0.400 0.600 0.000
Y00 Assault by blunt object
0.400 0.600 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.399 0.601 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.399 0.601 0.000
T39.4 Antirheumatics, not elsewhere classified
0.399 0.601 0.000
T39.2 Pyrazolone derivatives
0.399 0.601 0.000
G83.4 Cauda equina syndrome
0.399 0.601 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.399 0.601 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.398 0.601 0.000
G90 Disorders of autonomic nervous system
0.398 0.601 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.398 0.601 0.000
G92 Toxic encephalopathy
0.398 0.601 0.000
S90 Superficial injury of ankle and foot
0.398 0.602 0.000
M40-M43 Deforming dorsopathies
0.398 0.602 0.000
H82 Vertiginous syndromes in diseases classified elsewhere
0.397 0.602 0.000
T78.4 Allergy, unspecified
0.396 0.604 0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level
0.396 0.604 0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level
0.396 0.604 0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level
0.396 0.604 0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level
0.396 0.604 0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level
0.396 0.604 0.000
M47.29 Other spondylosis with radiculopathy (Site unspecified)
0.395 0.604 0.000
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)
0.395 0.604 0.000
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)
0.395 0.604 0.000
M47.24 Other spondylosis with radiculopathy (Thoracic region)
0.395 0.604 0.000
M47.23 Other spondylosis with radiculopathy (Cervicothoracic region)
0.395 0.604 0.000
M47.21 Other spondylosis with radiculopathy (Occipito-atlanto-axial region)
0.395 0.604 0.000
M47.20 Other spondylosis with radiculopathy (Multiple sites in spine)
0.395 0.604 0.000
T90.9 Sequelae of unspecified injury of head
0.395 0.605 0.000
M79.6 Pain in limb
0.395 0.605 0.000
F60-F69 Disorders of adult personality and behaviour
0.395 0.605 0.000
G61 Inflammatory polyneuropathy
0.394 0.606 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.394 0.606 0.000
Y04.5 Trade and service area
0.394 0.606 0.000
M54.64 Pain in thoracic spine (Thoracic region)
0.393 0.607 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.393 0.607 0.000
W29 Contact with other powered hand tools and household machinery
0.393 0.607 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.393 0.607 0.000
G56.2 Lesion of ulnar nerve
0.393 0.607 0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb
0.392 0.607 0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb
0.392 0.607 0.000
T93.4 Sequelae of injury of nerve of lower limb
0.392 0.607 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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