TreeWAS – Variant ID: rs10849689

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I35.0 Aortic (valve) stenosis	0.000	0.787	0.213
I35 Nonrheumatic aortic valve disorders	0.000	0.837	0.163
I35.1 Aortic (valve) insufficiency	0.000	0.852	0.148
I35.9 Aortic valve disorder, unspecified	0.000	0.865	0.135
I35.2 Aortic (valve) stenosis with insufficiency	0.000	0.882	0.118
I35.8 Other aortic valve disorders	0.000	0.886	0.114
Z98.0 Intestinal bypass and anastomosis status	0.033	0.967	0.000
S02.10 Fracture of base of skull (closed)	0.023	0.977	0.000
S02.60 Fracture of mandible (closed)	0.022	0.978	0.000
S02.1 Fracture of base of skull	0.021	0.979	0.000
C18.7 Sigmoid colon	0.021	0.979	0.000
S02.6 Fracture of mandible	0.021	0.979	0.000
S02 Fracture of skull and facial bones	0.020	0.980	0.000
Z63.0 Problems in relationship with spouse or partner	0.017	0.983	0.000
S06 Intracranial injury	0.016	0.984	0.000
S02.8 Fractures of other skull and facial bones	0.016	0.984	0.000
S02.7 Multiple fractures involving skull and facial bones	0.016	0.984	0.000
S02.0 Fracture of vault of skull	0.016	0.984	0.000
C18 Malignant neoplasm of colon	0.016	0.984	0.000
S00-S09 Injuries to the head	0.016	0.984	0.000
S02.4 Fracture of malar and maxillary bones	0.015	0.984	0.000
S02.11 Fracture of base of skull (open)	0.015	0.985	0.000
S01.0 Open wound of scalp	0.015	0.985	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.015	0.985	0.000
S02.61 Fracture of mandible (open)	0.015	0.985	0.000
S01.1 Open wound of eyelid and periocular area	0.015	0.985	0.000
S06.3 Focal brain injury	0.015	0.985	0.000
S01 Open wound of head	0.015	0.985	0.000
C18.0 Caecum	0.014	0.986	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.014	0.986	0.000
C18.3 Hepatic flexure	0.014	0.986	0.000
C16 Malignant neoplasm of stomach	0.014	0.986	0.000
Z63 Other problems related to primary support group, including family circumstances	0.014	0.986	0.000
C16.0 Cardia	0.014	0.986	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.013	0.987	0.000
S06.4 Epidural haemorrhage	0.013	0.987	0.000
S02.3 Fracture of orbital floor	0.013	0.987	0.000
Z63.5 Disruption of family by separation and divorce	0.013	0.987	0.000
Z63.8 Other specified problems related to primary support group	0.013	0.987	0.000
S02.2 Fracture of nasal bones	0.013	0.987	0.000
S06.9 Intracranial injury, unspecified	0.013	0.987	0.000
S01.2 Open wound of nose	0.013	0.987	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.013	0.987	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.013	0.987	0.000
S06.0 Concussion	0.013	0.987	0.000
C15-C26 Malignant neoplasms of digestive organs	0.013	0.987	0.000
C26.0 Intestinal tract, part unspecified	0.013	0.987	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.012	0.988	0.000
S02.70 Multiple fractures involving skull and facial bones (closed)	0.012	0.988	0.000
C16.9 Stomach, unspecified	0.012	0.988	0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm	0.012	0.988	0.000
S02.00 Fracture of vault of skull (closed)	0.012	0.988	0.000
C16.6 Greater curvature of stomach, unspecified	0.012	0.988	0.000
S06.8 Other intracranial injuries	0.012	0.988	0.000
S02.5 Fracture of tooth	0.012	0.988	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.012	0.988	0.000
S06.7 Intracranial injury with prolonged coma	0.012	0.988	0.000
S06.1 Traumatic cerebral oedema	0.012	0.988	0.000
C18.8 Overlapping lesion of colon	0.012	0.988	0.000
Z63.6 Dependent relative needing care at home	0.012	0.988	0.000
S06.2 Diffuse brain injury	0.012	0.988	0.000
S02.81 Fractures of other skull and facial bones (open)	0.012	0.988	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.012	0.988	0.000
C16.3 Pyloric antrum	0.012	0.988	0.000
S02.71 Multiple fractures involving skull and facial bones (open)	0.011	0.988	0.000
S02.01 Fracture of vault of skull (open)	0.011	0.989	0.000
S08 Traumatic amputation of part of head	0.011	0.989	0.000
S07 Crushing injury of head	0.011	0.989	0.000
S04 Injury of cranial nerves	0.011	0.989	0.000
S02.41 Fracture of malar and maxillary bones (open)	0.011	0.989	0.000
S06.40 Epidural haemorrhage (without open intracranial wound)	0.011	0.989	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.011	0.989	0.000
C18.5 Splenic flexure	0.011	0.989	0.000
S06.5 Traumatic subdural haemorrhage	0.011	0.989	0.000
C16.4 Pylorus	0.011	0.989	0.000
S06.31 Focal brain injury (with open intracranial wound)	0.011	0.989	0.000
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.011	0.989	0.000
S05 Injury of eye and orbit	0.011	0.989	0.000
C16.8 Overlapping lesion of stomach	0.010	0.989	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.011	0.989	0.000
C16.1 Fundus of stomach	0.010	0.989	0.000
Z63.9 Problem related to primary support group, unspecified	0.010	0.989	0.000
Z63.3 Absence of family member	0.010	0.989	0.000
Z63.2 Inadequate family support	0.010	0.989	0.000
Z63.1 Problems in relationship with parents and in-laws	0.010	0.989	0.000
C16.5 Lesser curvature of stomach, unspecified	0.010	0.990	0.000
C16.2 Body of stomach	0.010	0.990	0.000
C21 Malignant neoplasm of anus and anal canal	0.010	0.990	0.000
S06.00 Concussion (without open intracranial wound)	0.010	0.990	0.000
S01.3 Open wound of ear	0.010	0.990	0.000
C17 Malignant neoplasm of small intestine	0.010	0.990	0.000
C18.4 Transverse colon	0.010	0.990	0.000
S06.41 Epidural haemorrhage (with open intracranial wound)	0.010	0.990	0.000
S02.31 Fracture of orbital floor (open)	0.010	0.990	0.000
S02.21 Fracture of nasal bones (open)	0.010	0.990	0.000
I67.8 Other specified cerebrovascular diseases	0.000	0.990	0.010
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.009	0.990	0.000
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.009	0.991	0.000
S06.01 Concussion (with open intracranial wound)	0.009	0.991	0.000
C18.1 Appendix	0.009	0.991	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.009	0.991	0.000
C18.2 Ascending colon	0.009	0.991	0.000
C21.0 Anus, unspecified	0.009	0.991	0.000
C24.0 Extrahepatic bile duct	0.009	0.991	0.000
C26.8 Overlapping lesion of digestive system	0.009	0.991	0.000
C26.1 Spleen	0.009	0.991	0.000
S06.80 Other intracranial injuries (without open intracranial wound)	0.009	0.991	0.000
C17.2 Ileum	0.009	0.991	0.000
C26.9 Ill-defined sites within the digestive system	0.009	0.991	0.000
S01.9 Open wound of head, part unspecified	0.009	0.991	0.000
S06.81 Other intracranial injuries (with open intracranial wound)	0.009	0.991	0.000
S02.51 Fracture of tooth (open)	0.009	0.991	0.000
S05.8 Other injuries of eye and orbit	0.009	0.991	0.000
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.009	0.991	0.000
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.009	0.991	0.000
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.009	0.991	0.000
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.009	0.991	0.000
S03.2 Dislocation of tooth	0.009	0.991	0.000
S05.6 Penetrating wound of eyeball without foreign body	0.009	0.991	0.000
C20 Malignant neoplasm of rectum	0.009	0.991	0.000
S06.21 Diffuse brain injury (with open intracranial wound)	0.008	0.991	0.000
S03.5 Sprain and strain of joints and ligaments of other and unspecified parts of head	0.008	0.991	0.000
S03.4 Sprain and strain of jaw	0.008	0.991	0.000
S03.3 Dislocation of other and unspecified parts of head	0.008	0.991	0.000
S03.1 Dislocation of septal cartilage of nose	0.008	0.991	0.000
S03.0 Dislocation of jaw	0.008	0.991	0.000
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue	0.008	0.991	0.000
Z57.3 Occupational exposure to other air contaminants	0.009	0.991	0.000
C18.9 Colon, unspecified	0.008	0.992	0.000
S09 Other and unspecified injuries of head	0.008	0.992	0.000
S04.9 Injury of unspecified cranial nerve	0.008	0.992	0.000
S04.8 Injury of other cranial nerves	0.008	0.992	0.000
S04.7 Injury of accessory nerve	0.008	0.992	0.000
S04.6 Injury of acoustic nerve	0.008	0.992	0.000
S04.5 Injury of facial nerve	0.008	0.992	0.000
S04.4 Injury of abducent nerve	0.008	0.992	0.000
S04.3 Injury of trigeminal nerve	0.008	0.992	0.000
S04.2 Injury of trochlear nerve	0.008	0.992	0.000
S04.1 Injury of oculomotor nerve	0.008	0.992	0.000
S04.0 Injury of optic nerve and pathways	0.008	0.992	0.000
S07.9 Crushing injury of head, part unspecified	0.008	0.992	0.000
S07.8 Crushing injury of other parts of head	0.008	0.992	0.000
S07.1 Crushing injury of skull	0.008	0.992	0.000
S07.0 Crushing injury of face	0.008	0.992	0.000
S08.9 Traumatic amputation of unspecified part of head	0.008	0.992	0.000
S08.8 Traumatic amputation of other parts of head	0.008	0.992	0.000
S08.1 Traumatic amputation of ear	0.008	0.992	0.000
S08.0 Avulsion of scalp	0.008	0.992	0.000
S02.30 Fracture of orbital floor (closed)	0.008	0.992	0.000
C24.9 Biliary tract, unspecified	0.008	0.992	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.008	0.992	0.000
Z63.7 Other stressful life events affecting family and household	0.008	0.992	0.000
S05.3 Ocular laceration without prolapse or loss of intraocular tissue	0.008	0.992	0.000
S01.4 Open wound of cheek and temporomandibular area	0.008	0.992	0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters	0.000	0.992	0.008
C21.8 Overlapping lesion of rectum, anus and anal canal	0.008	0.992	0.000
C22.1 Intrahepatic bile duct carcinoma	0.008	0.992	0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.008	0.992	0.000
S05.5 Penetrating wound of eyeball with foreign body	0.008	0.992	0.000
S02.20 Fracture of nasal bones (closed)	0.008	0.992	0.000
C23 Malignant neoplasm of gallbladder	0.008	0.992	0.000
S05.7 Avulsion of eye	0.008	0.992	0.000
S05.4 Penetrating wound of orbit with or without foreign body	0.008	0.992	0.000
I67 Other cerebrovascular diseases	0.000	0.992	0.008
C24.8 Overlapping lesion of biliary tract	0.008	0.992	0.000
C17.0 Duodenum	0.008	0.992	0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.008	0.992	0.000
C21.2 Cloacogenic zone	0.008	0.992	0.000
Z57 Occupational exposure to risk-factors	0.008	0.992	0.000
I67.2 Cerebral atherosclerosis	0.000	0.992	0.008
C15 Malignant neoplasm of oesophagus	0.008	0.992	0.000
C17.8 Overlapping lesion of small intestine	0.007	0.992	0.000
C17.3 Meckel's diverticulum	0.007	0.992	0.000
C17.1 Jejunum	0.007	0.992	0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.007	0.993	0.000
J92.9 Pleural plaque without asbestos	0.007	0.993	0.000
S05.9 Injury of eye and orbit, part unspecified	0.007	0.993	0.000
C22.7 Other specified carcinomas of liver	0.007	0.993	0.000
C22.4 Other sarcomas of liver	0.007	0.993	0.000
C22.3 Angiosarcoma of liver	0.007	0.993	0.000
C22.2 Hepatoblastoma	0.007	0.993	0.000
S09.0 Injury of blood vessels of head, not elsewhere classified	0.007	0.993	0.000
C24.1 Ampulla of Vater	0.007	0.993	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.007	0.993	0.000
C18.6 Descending colon	0.007	0.993	0.000
C15.4 Middle third of oesophagus	0.007	0.993	0.000
I67.9 Cerebrovascular disease, unspecified	0.000	0.993	0.007
S01.7 Multiple open wounds of head	0.006	0.993	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.000	0.993	0.006
H65.3 Chronic mucoid otitis media	0.007	0.993	0.000
S09.8 Other specified injuries of head	0.006	0.994	0.000
Z57.8 Occupational exposure to other risk-factors	0.006	0.994	0.000
Z59 Problems related to housing and economic circumstances	0.006	0.994	0.000
S09.7 Multiple injuries of head	0.006	0.994	0.000
S09.2 Traumatic rupture of ear drum	0.006	0.994	0.000
S09.1 Injury of muscle and tendon of head	0.006	0.994	0.000
Y60.0 During surgical operation	0.006	0.994	0.000
C22.9 Liver, unspecified	0.006	0.994	0.000
Z64 Problems related to certain psychosocial circumstances	0.006	0.994	0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.006	0.994	0.000
S02.50 Fracture of tooth (closed)	0.006	0.994	0.000
C15.3 Upper third of oesophagus	0.006	0.994	0.000
Z63.4 Disappearance and death of family member	0.006	0.994	0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension	0.000	0.994	0.006
C21.1 Anal canal	0.006	0.994	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.000	0.994	0.006
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.000	0.994	0.006
I67.5 Moyamoya disease	0.000	0.994	0.006
I67.4 Hypertensive encephalopathy	0.000	0.994	0.006
I67.3 Progressive vascular leukoencephalopathy	0.000	0.994	0.006
Z65 Problems related to other psychosocial circumstances	0.006	0.994	0.000
Z57.2 Occupational exposure to dust	0.006	0.994	0.000
Z62 Other problems related to upbringing	0.006	0.994	0.000
Z61 Problems related to negative life events in childhood	0.006	0.994	0.000
Z55 Problems related to education and literacy	0.006	0.994	0.000
C17.9 Small intestine, unspecified	0.006	0.994	0.000
C22.0 Liver cell carcinoma	0.006	0.994	0.000
Z57.9 Occupational exposure to unspecified risk-factor	0.006	0.994	0.000
Z57.7 Occupational exposure to vibration	0.006	0.994	0.000
Z57.6 Occupational exposure to extreme temperature	0.006	0.994	0.000
Z57.4 Occupational exposure to toxic agents in agriculture	0.006	0.994	0.000
Z57.1 Occupational exposure to radiation	0.006	0.994	0.000
Z57.0 Occupational exposure to noise	0.006	0.994	0.000
C15.8 Overlapping lesion of oesophagus	0.006	0.994	0.000
C15.2 Abdominal part of oesophagus	0.006	0.994	0.000
C15.1 Thoracic part of oesophagus	0.006	0.994	0.000
C15.0 Cervical part of oesophagus	0.006	0.994	0.000
Z59.9 Problem relating to housing and economic circumstances, unspecified	0.006	0.994	0.000
S01.5 Open wound of lip and oral cavity	0.006	0.994	0.000
G47.9 Sleep disorder, unspecified	0.005	0.995	0.000
Z64.0 Problems related to unwanted pregnancy	0.005	0.995	0.000
Z58 Problems related to physical environment	0.005	0.995	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.000	0.995	0.005
I67.1 Cerebral aneurysm, nonruptured	0.000	0.995	0.005
H65.9 Nonsuppurative otitis media, unspecified	0.005	0.995	0.000
Z59.8 Other problems relating to housing and economic circumstances	0.005	0.995	0.000
Z59.1 Inadequate housing	0.005	0.995	0.000
Z59.7 Insufficient social insurance and welfare support	0.005	0.995	0.000
Z59.6 Low income	0.005	0.995	0.000
Z59.5 Extreme poverty	0.005	0.995	0.000
Z59.4 Lack of adequate food	0.005	0.995	0.000
Z59.3 Problems related to living in residential institution	0.005	0.995	0.000
Z59.2 Discord with neighbours, lodgers and landlord	0.005	0.995	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.005	0.995	0.000
R07.2 Precordial pain	0.005	0.995	0.000
S01.8 Open wound of other parts of head	0.005	0.995	0.000
Z64.4 Discord with counsellors	0.005	0.995	0.000
Z64.3 Seeking and accepting behavioural and psychological interventions known to be hazardous and harmful	0.005	0.995	0.000
Z64.2 Seeking and accepting physical, nutritional and chemical interventions known to be hazardous and harmful	0.005	0.995	0.000
Z64.1 Problems related to multiparity	0.005	0.995	0.000
M81.99 Osteoporosis, unspecified (Site unspecified)	0.000	0.995	0.005
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.005	0.995	0.000
M24.2 Disorder of ligament	0.005	0.995	0.000
S05.1 Contusion of eyeball and orbital tissues	0.004	0.995	0.000
Z08 Follow-up examination after treatment for malignant neoplasm	0.005	0.995	0.000
Z56 Problems related to employment and unemployment	0.005	0.995	0.000
Z65.8 Other specified problems related to psychosocial circumstances	0.004	0.995	0.000
M24 Other specific joint derangements	0.005	0.995	0.000
M24.21 Disorder of ligament (Shoulder region)	0.004	0.995	0.000
Z65.9 Problem related to unspecified psychosocial circumstances	0.004	0.995	0.000
Z65.5 Exposure to disaster, war and other hostilities	0.004	0.995	0.000
Z65.4 Victim of crime and terrorism	0.004	0.995	0.000
Z65.3 Problems related to other legal circumstances	0.004	0.995	0.000
Z65.2 Problems related to release from prison	0.004	0.995	0.000
Z65.1 Imprisonment and other incarceration	0.004	0.995	0.000
Z65.0 Conviction in civil and criminal proceedings without imprisonment	0.004	0.995	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.995	0.005
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.004	0.996	0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.004	0.996	0.000
H65 Nonsuppurative otitis media	0.004	0.996	0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.004	0.996	0.000
Z55.9 Problems relating to education and literacy, unspecified	0.004	0.996	0.000
Z55.8 Other problems relating to education and literacy	0.004	0.996	0.000
Z55.4 Educational maladjustment and discord with teachers and classmates	0.004	0.996	0.000
Z55.3 Underachievement in school	0.004	0.996	0.000
Z55.2 Failed examinations	0.004	0.996	0.000
Z55.1 Schooling unavailable and unattainable	0.004	0.996	0.000
Z55.0 Illiteracy and low-level literacy	0.004	0.996	0.000
Z61.9 Negative life events in childhood, unspecified	0.004	0.996	0.000
Z61.8 Other negative life events in childhood	0.004	0.996	0.000
Z61.7 Personal frightening experience in childhood	0.004	0.996	0.000
Z61.6 Problems related to alleged physical abuse of child	0.004	0.996	0.000
Z61.5 Problems related to alleged sexual abuse of child by person outside primary support group	0.004	0.996	0.000
Z61.4 Problems related to alleged sexual abuse of child by person within primary support group	0.004	0.996	0.000
Z61.3 Events resulting in loss of self-esteem in childhood	0.004	0.996	0.000
Z61.2 Altered pattern of family relationships in childhood	0.004	0.996	0.000
Z61.1 Removal from home in childhood	0.004	0.996	0.000
Z61.0 Loss of love relationship in childhood	0.004	0.996	0.000
Z62.9 Problem related to upbringing, unspecified	0.004	0.996	0.000
Z62.8 Other specified problems related to upbringing	0.004	0.996	0.000
Z62.6 Inappropriate parental pressure and other abnormal qualities of upbringing	0.004	0.996	0.000
Z62.5 Other problems related to neglect in upbringing	0.004	0.996	0.000
Z62.4 Emotional neglect of child	0.004	0.996	0.000
Z62.3 Hostility towards and scapegoating of child	0.004	0.996	0.000
Z62.2 Institutional upbringing	0.004	0.996	0.000
Z62.1 Parental overprotection	0.004	0.996	0.000
Z62.0 Inadequate parental supervision and control	0.004	0.996	0.000
Z58.8 Other problems related to physical environment	0.004	0.996	0.000
M81.9 Osteoporosis, unspecified	0.000	0.996	0.004
Z59.0 Homelessness	0.004	0.996	0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm	0.004	0.996	0.000
Z58.9 Problem related to physical environment, unspecified	0.004	0.996	0.000
Z58.7 Exposure to tobacco smoke	0.004	0.996	0.000
Z58.6 Inadequate drinking-water supply	0.004	0.996	0.000
Z58.5 Exposure to other pollution	0.004	0.996	0.000
Z58.4 Exposure to radiation	0.004	0.996	0.000
Z58.3 Exposure to soil pollution	0.004	0.996	0.000
Z58.2 Exposure to water pollution	0.004	0.996	0.000
Z58.0 Exposure to noise	0.004	0.996	0.000
D70 Agranulocytosis	0.004	0.996	0.000
E05.9 Thyrotoxicosis, unspecified	0.000	0.996	0.004
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.004	0.996	0.000
M24.1 Other articular cartilage disorders	0.004	0.996	0.000
M24.23 Disorder of ligament (Forearm)	0.004	0.996	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.004	0.996	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.004	0.996	0.000
Y60.8 During other surgical and medical care	0.004	0.996	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.004	0.996	0.000
D22.6 Melanocytic naevi of upper limb, including shoulder	0.000	0.996	0.004
Y60.5 During heart catheterisation	0.004	0.996	0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.004	0.996	0.000
M81.98 Osteoporosis, unspecified (Other)	0.000	0.996	0.004
M24.7 Protrusio acetabuli	0.004	0.996	0.000
M24.24 Disorder of ligament (Hand)	0.004	0.996	0.000
M24.5 Contracture of joint	0.004	0.996	0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.004	0.996	0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.004	0.996	0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.004	0.996	0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.004	0.996	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.004	0.996	0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.004	0.996	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.004	0.996	0.000
H65.0 Acute serous otitis media	0.004	0.996	0.000
M24.29 Disorder of ligament (Site unspecified)	0.004	0.996	0.000
M24.28 Disorder of ligament (Other)	0.004	0.996	0.000
M24.25 Disorder of ligament (Pelvic region and thigh)	0.004	0.996	0.000
M24.22 Disorder of ligament (Upper arm)	0.004	0.996	0.000
M24.20 Disorder of ligament (Multiple sites)	0.004	0.996	0.000
C15.5 Lower third of oesophagus	0.004	0.996	0.000
M24.0 Loose body in joint	0.004	0.996	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.004	0.996	0.000
Z56.7 Other and unspecified problems related to employment	0.003	0.996	0.000
Z56.5 Uncongenial work	0.003	0.996	0.000
Z56.4 Discord with boss and workmates	0.003	0.996	0.000
Z56.2 Threat of job loss	0.003	0.996	0.000
Z56.1 Change of job	0.003	0.996	0.000
M24.26 Disorder of ligament (Lower leg)	0.003	0.996	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.000	0.996	0.003
K14.0 Glossitis	0.000	0.996	0.004
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.996	0.004
M24.9 Joint derangement, unspecified	0.003	0.996	0.000
O03.4 Incomplete, without complication	0.000	0.996	0.004
C81.9 Hodgkin's disease, unspecified	0.003	0.997	0.000
H65.1 Other acute nonsuppurative otitis media	0.003	0.997	0.000
Y60.9 During unspecified surgical and medical care	0.003	0.997	0.000
Y60.7 During administration of enema	0.003	0.997	0.000
Y60.6 During aspiration, puncture and other catheterisation	0.003	0.997	0.000
Y60.3 During injection or immunisation	0.003	0.997	0.000
Y60.2 During kidney dialysis or other perfusion	0.003	0.997	0.000
Y60.1 During infusion or transfusion	0.003	0.997	0.000
S72.10 Pertrochanteric fracture (closed)	0.000	0.997	0.003
G47.3 Sleep apnoea	0.003	0.997	0.000
M24.54 Contracture of joint (Hand)	0.003	0.997	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.003	0.997	0.000
Z60 Problems related to social environment	0.003	0.997	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.003	0.997	0.000
Z56.3 Stressful work schedule	0.003	0.997	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.000	0.997	0.003
M81.93 Osteoporosis, unspecified (Forearm)	0.000	0.997	0.003
M81.92 Osteoporosis, unspecified (Upper arm)	0.000	0.997	0.003
M81.91 Osteoporosis, unspecified (Shoulder region)	0.000	0.997	0.003
K59.8 Other specified functional intestinal disorders	0.003	0.997	0.000
Z56.6 Other physical and mental strain related to work	0.003	0.997	0.000
M24.6 Ankylosis of joint	0.003	0.997	0.000
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm	0.003	0.997	0.000
M24.75 Protrusio acetabuli-Pelvic/thigh	0.003	0.997	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.000	0.997	0.003
Y60.4 During endoscopic examination	0.003	0.997	0.000
E03.9 Hypothyroidism, unspecified	0.000	0.997	0.003
C15.9 Oesophagus, unspecified	0.003	0.997	0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.003	0.997	0.000
M24.04 Loose body in joint (Hand)	0.003	0.997	0.000
M24.19 Other articular cartilage disorders (Site unspecified)	0.003	0.997	0.000
M24.18 Other articular cartilage disorders (Other)	0.003	0.997	0.000
M24.14 Other articular cartilage disorders (Hand)	0.003	0.997	0.000
M24.12 Other articular cartilage disorders (Upper arm)	0.003	0.997	0.000
M24.10 Other articular cartilage disorders (Multiple sites)	0.003	0.997	0.000
Z56.0 Unemployment, unspecified	0.003	0.997	0.000
H61.1 Non-infective disorders of pinna	0.003	0.997	0.000
M24.57 Contracture of joint (Ankle and foot)	0.003	0.997	0.000
S00 Superficial injury of head	0.003	0.997	0.000
M24.79 Protrusio acetabuli-Site unspec	0.003	0.997	0.000
M24.78 Protrusio acetabuli-Other	0.003	0.997	0.000
M24.77 Protrusio acetabuli-Ankle/foot	0.003	0.997	0.000
M24.76 Protrusio acetabuli-Lower leg	0.003	0.997	0.000
M24.74 Protrusio acetabuli-Hand	0.003	0.997	0.000
M24.73 Protrusio acetabuli-Forearm	0.003	0.997	0.000
M24.72 Protrusio acetabuli-Upper arm	0.003	0.997	0.000
M24.71 Protrusio acetabuli-Shldr region	0.003	0.997	0.000
M24.70 Protrusio acetabuli-Mult sites	0.003	0.997	0.000
S00.2 Other superficial injuries of eyelid and periocular area	0.003	0.997	0.000
Z58.1 Exposure to air pollution	0.003	0.997	0.000
M24.59 Contracture of joint (Site unspecified)	0.003	0.997	0.000
M24.58 Contracture of joint (Other)	0.003	0.997	0.000
M24.55 Contracture of joint (Pelvic region and thigh)	0.003	0.997	0.000
M24.53 Contracture of joint (Forearm)	0.003	0.997	0.000
M24.52 Contracture of joint (Upper arm)	0.003	0.997	0.000
M24.50 Contracture of joint (Multiple sites)	0.003	0.997	0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.003	0.997	0.000
M24.01 Loose body in joint (Shoulder region)	0.003	0.997	0.000
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.003	0.997	0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.003	0.997	0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.003	0.997	0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.003	0.997	0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.003	0.997	0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.003	0.997	0.000
Z57.5 Occupational exposure to toxic agents in other industries	0.003	0.997	0.000
C25 Malignant neoplasm of pancreas	0.003	0.997	0.000
G47 Sleep disorders	0.003	0.997	0.000
M24.09 Loose body in joint (Site unspecified)	0.003	0.997	0.000
M24.08 Loose body in joint (Other)	0.003	0.997	0.000
M24.06 Loose body in joint-Lower leg	0.003	0.997	0.000
M24.05 Loose body in joint (Pelvic region and thigh)	0.003	0.997	0.000
M24.00 Loose body in joint (Multiple sites)	0.003	0.997	0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.003	0.997	0.000
O03.9 Complete or unspecified, without complication	0.000	0.997	0.003
M24.03 Loose body in joint (Forearm)	0.003	0.997	0.000
M24.56 Contracture of joint (Lower leg)	0.003	0.997	0.000
M24.02 Loose body in joint (Upper arm)	0.003	0.997	0.000
M24.99 Joint derangement, unspecified (Site unspecified)	0.003	0.997	0.000
M24.98 Joint derangement, unspecified (Other)	0.003	0.997	0.000
M24.97 Joint derangement, unspecified (Ankle and foot)	0.003	0.997	0.000
M24.96 Joint derangement, unspecified (Lower leg)	0.003	0.997	0.000
M24.95 Joint derangement, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
M24.94 Joint derangement, unspecified (Hand)	0.003	0.997	0.000
M24.93 Joint derangement, unspecified (Forearm)	0.003	0.997	0.000
M24.92 Joint derangement, unspecified (Upper arm)	0.003	0.997	0.000
M24.91 Joint derangement, unspecified (Shoulder region)	0.003	0.997	0.000
M24.90 Joint derangement, unspecified (Multiple sites)	0.003	0.997	0.000
E05.5 Thyroid crisis or storm	0.000	0.997	0.003
E05.4 Thyrotoxicosis factitia	0.000	0.997	0.003
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.997	0.003
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.997	0.003
S00.3 Superficial injury of nose	0.003	0.997	0.000
H65.4 Other chronic nonsuppurative otitis media	0.003	0.997	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.003	0.997	0.000
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)	0.003	0.997	0.000
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)	0.003	0.997	0.000
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)	0.003	0.997	0.000
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)	0.003	0.997	0.000
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)	0.003	0.997	0.000
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)	0.003	0.997	0.000
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)	0.003	0.997	0.000
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)	0.003	0.997	0.000
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)	0.003	0.997	0.000
Z60.9 Problem related to social environment, unspecified	0.003	0.997	0.000
Z60.8 Other problems related to social environment	0.003	0.997	0.000
Z60.5 Target of perceived adverse discrimination and persecution	0.003	0.997	0.000
Z60.4 Social exclusion and rejection	0.003	0.997	0.000
Z60.3 Acculturation difficulty	0.003	0.997	0.000
Z60.1 Atypical parenting situation	0.003	0.997	0.000
Z60.0 Problems of adjustment to life-cycle transitions	0.003	0.997	0.000
M24.51 Contracture of joint (Shoulder region)	0.003	0.997	0.000
M24.66 Ankylosis of joint (Lower leg)	0.003	0.997	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.003	0.997	0.000
E05.8 Other thyrotoxicosis	0.000	0.997	0.003
H65.2 Chronic serous otitis media	0.003	0.997	0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.003	0.997	0.000
M24.69 Ankylosis of joint (Site unspecified)	0.002	0.997	0.000
M24.68 Ankylosis of joint (Other)	0.002	0.997	0.000
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.002	0.997	0.000
M24.64 Ankylosis of joint (Hand)	0.002	0.997	0.000
M24.63 Ankylosis of joint (Forearm)	0.002	0.997	0.000
M24.62 Ankylosis of joint (Upper arm)	0.002	0.997	0.000
M24.61 Ankylosis of joint (Shoulder region)	0.002	0.997	0.000
M24.60 Ankylosis of joint (Multiple sites)	0.002	0.997	0.000
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.002	0.997	0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.000	0.997	0.003
M24.07 Loose body in joint (Ankle and foot)	0.002	0.997	0.000
O03 Spontaneous abortion	0.000	0.997	0.003
S00.7 Multiple superficial injuries of head	0.002	0.997	0.000
C25.3 Pancreatic duct	0.002	0.998	0.000
K25.7 Chronic without haemorrhage or perforation	0.002	0.998	0.000
N85.0 Endometrial glandular hyperplasia	0.000	0.998	0.002
S00.4 Superficial injury of ear	0.002	0.998	0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.002	0.998	0.000
Z46.8 Fitting and adjustment of other specified devices	0.002	0.998	0.000
E03 Other hypothyroidism	0.000	0.998	0.002
M24.67 Ankylosis of joint (Ankle and foot)	0.002	0.998	0.000
C25.8 Overlapping lesion of pancreas	0.002	0.998	0.000
C25.7 Other parts of pancreas	0.002	0.998	0.000
C25.4 Endocrine pancreas	0.002	0.998	0.000
G47.2 Disorders of the sleep-wake schedule	0.002	0.998	0.000
S72.1 Pertrochanteric fracture	0.000	0.998	0.002
C81 Hodgkin's disease	0.002	0.998	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
B97.8 Other viral agents as the cause of diseases classified to other chapters	0.000	0.998	0.002
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.000	0.998	0.002
Z08.8 Follow-up examination after other treatment for malignant neoplasm	0.002	0.998	0.000
G47.4 Narcolepsy and cataplexy	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations