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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs10908523
log Bayes Factor = 11.6102
Chromosome 1   position 156,830,218  (GRCh37) Explore rs10908523 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.999 0.001 0.000
I25 Chronic ischaemic heart disease
0.998 0.002 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.998 0.002 0.000
L03 Cellulitis
0.997 0.003 0.000
S00-S09 Injuries to the head
0.996 0.004 0.000
I60-I69 Cerebrovascular diseases
0.996 0.004 0.000
Chapter VII Diseases of the eye and adnexa
0.995 0.005 0.000
L03.1 Cellulitis of other parts of limb
0.990 0.010 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.985 0.015 0.000
H25-H28 Disorders of lens
0.977 0.023 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.977 0.023 0.000
H26 Other cataract
0.973 0.027 0.000
I80 Phlebitis and thrombophlebitis
0.973 0.027 0.000
I24 Other acute ischaemic heart diseases
0.971 0.029 0.000
S70-S79 Injuries to the hip and thigh
0.970 0.030 0.000
Chapter XX External causes of morbidity and mortality
0.968 0.032 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.967 0.033 0.000
L03.0 Cellulitis of finger and toe
0.966 0.034 0.000
S00 Superficial injury of head
0.960 0.040 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.959 0.041 0.000
H26.4 After-cataract
0.956 0.044 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.950 0.050 0.000
I67 Other cerebrovascular diseases
0.950 0.050 0.000
S90-S99 Injuries to the ankle and foot
0.943 0.057 0.000
S72 Fracture of femur
0.943 0.057 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.937 0.063 0.000
S06 Intracranial injury
0.932 0.068 0.000
H26.8 Other specified cataract
0.932 0.068 0.000
E20-E35 Disorders of other endocrine glands
0.930 0.070 0.000
I25.1 Atherosclerotic heart disease
0.929 0.071 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.929 0.071 0.000
S72.0 Fracture of neck of femur
0.924 0.076 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.916 0.084 0.000
I95 Hypotension
0.915 0.085 0.000
S80-S89 Injuries to the knee and lower leg
0.915 0.085 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.913 0.087 0.000
S72.00 Fracture of neck of femur (closed)
0.911 0.089 0.000
L40-L45 Papulosquamous disorders
0.908 0.092 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.908 0.092 0.000
S00.1 Contusion of eyelid and periocular area
0.908 0.092 0.000
I24.8 Other forms of acute ischaemic heart disease
0.904 0.096 0.000
S01 Open wound of head
0.902 0.098 0.000
I62 Other nontraumatic intracranial haemorrhage
0.894 0.106 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.893 0.107 0.000
I69 Sequelae of cerebrovascular disease
0.886 0.114 0.000
H55-H59 Other disorders of eye and adnexa
0.883 0.116 0.000
I20 Angina pectoris
0.883 0.117 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.882 0.118 0.000
I22 Subsequent myocardial infarction
0.881 0.119 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.879 0.121 0.000
I85 Oesophageal varices
0.879 0.121 0.000
I67.1 Cerebral aneurysm, nonruptured
0.878 0.122 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.876 0.124 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.873 0.127 0.000
S80 Superficial injury of lower leg
0.866 0.134 0.000
L50-L54 Urticaria and erythema
0.866 0.134 0.000
H52 Disorders of refraction and accommodation
0.865 0.135 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.864 0.136 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.861 0.139 0.000
Y57 Other and unspecified drugs and medicaments
0.861 0.139 0.000
S92 Fracture of foot, except ankle
0.861 0.139 0.000
L03.8 Cellulitis of other sites
0.860 0.140 0.000
E10-E14 Diabetes mellitus
0.859 0.141 0.000
Y52 Agents primarily affecting the cardiovascular system
0.857 0.143 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.857 0.143 0.000
I25.4 Coronary artery aneurysm
0.853 0.147 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.847 0.153 0.000
S02 Fracture of skull and facial bones
0.841 0.159 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.834 0.166 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.831 0.169 0.000
H57 Other disorders of eye and adnexa
0.830 0.170 0.000
Chapter XXII Codes for special purposes
0.830 0.170 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.829 0.171 0.000
Y40 Systemic antibiotics
0.828 0.172 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.827 0.173 0.000
I20.9 Angina pectoris, unspecified
0.827 0.173 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.826 0.174 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.818 0.182 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.816 0.184 0.000
S06.5 Traumatic subdural haemorrhage
0.815 0.185 0.000
Y43 Primarily systemic agents
0.814 0.186 0.000
I95.2 Hypotension due to drugs
0.814 0.186 0.000
L40 Psoriasis
0.813 0.187 0.000
E11 Non-insulin-dependent diabetes mellitus
0.812 0.188 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.810 0.190 0.000
S00.0 Superficial injury of scalp
0.808 0.192 0.000
H53-H54 Visual disturbances and blindness
0.806 0.194 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.802 0.198 0.000
I67.8 Other specified cerebrovascular diseases
0.799 0.201 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.798 0.202 0.000
Chapter I Certain infectious and parasitic diseases
0.798 0.202 0.000
T79-T79 Certain early complications of trauma
0.798 0.202 0.000
I85.9 Oesophageal varices without bleeding
0.796 0.204 0.000
I73 Other peripheral vascular diseases
0.795 0.205 0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.793 0.206 0.000
S90 Superficial injury of ankle and foot
0.792 0.208 0.000
I60 Subarachnoid haemorrhage
0.790 0.210 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.787 0.213 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.786 0.214 0.000
I95.9 Hypotension, unspecified
0.783 0.217 0.000
E16 Other disorders of pancreatic internal secretion
0.778 0.222 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.778 0.222 0.000
S00.8 Superficial injury of other parts of head
0.778 0.222 0.000
H49 Paralytic strabismus
0.777 0.223 0.000
E22 Hyperfunction of pituitary gland
0.775 0.225 0.000
I72 Other aneurysm
0.775 0.225 0.000
E21.0 Primary hyperparathyroidism
0.772 0.228 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.772 0.228 0.000
L03.2 Cellulitis of face
0.771 0.229 0.000
L03.9 Cellulitis, unspecified
0.769 0.231 0.000
S06.2 Diffuse brain injury
0.768 0.232 0.000
S10-S19 Injuries to the neck
0.766 0.233 0.000
O20 Haemorrhage in early pregnancy
0.762 0.238 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.762 0.238 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.761 0.239 0.000
I20.8 Other forms of angina pectoris
0.758 0.242 0.000
E70-E90 Metabolic disorders
0.758 0.242 0.000
T86 Failure and rejection of transplanted organs and tissues
0.758 0.242 0.000
S80.1 Contusion of other and unspecified parts of lower leg
0.757 0.243 0.000
S40-S49 Injuries to the shoulder and upper arm
0.756 0.244 0.000
I70 Atherosclerosis
0.756 0.244 0.000
H30-H36 Disorders of choroid and retina
0.756 0.244 0.000
E11.9 Without complications
0.755 0.245 0.000
H52.2 Astigmatism
0.755 0.245 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.750 0.250 0.000
L20-L30 Dermatitis and eczema
0.750 0.250 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.749 0.250 0.000
S01.8 Open wound of other parts of head
0.749 0.251 0.000
L40.9 Psoriasis, unspecified
0.749 0.251 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.747 0.253 0.000
I63 Cerebral infarction
0.746 0.254 0.000
S20-S29 Injuries to the thorax
0.746 0.254 0.000
E40-E46 Malnutrition
0.744 0.255 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.743 0.257 0.000
L53 Other erythematous conditions
0.743 0.257 0.000
S01.1 Open wound of eyelid and periocular area
0.743 0.257 0.000
H57.1 Ocular pain
0.742 0.258 0.000
S80.9 Superficial injury of lower leg, unspecified
0.742 0.258 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.740 0.260 0.000
H26.1 Traumatic cataract
0.740 0.260 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.739 0.260 0.000
S72.4 Fracture of lower end of femur
0.739 0.261 0.000
E21.3 Hyperparathyroidism, unspecified
0.738 0.262 0.000
Y57.5 X-ray contrast media
0.738 0.262 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.737 0.263 0.000
I73.9 Peripheral vascular disease, unspecified
0.737 0.263 0.000
I95.8 Other hypotension
0.736 0.264 0.000
S70 Superficial injury of hip and thigh
0.734 0.266 0.000
W20-W49 Exposure to inanimate mechanical forces
0.734 0.266 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.733 0.267 0.000
I25.5 Ischaemic cardiomyopathy
0.733 0.267 0.000
I95.1 Orthostatic hypotension
0.733 0.267 0.000
L43 Lichen planus
0.733 0.267 0.000
H54 Blindness and low vision
0.732 0.268 0.000
S92.0 Fracture of calcaneus
0.732 0.268 0.000
S32 Fracture of lumbar spine and pelvis
0.731 0.269 0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)
0.731 0.269 0.000
S01.9 Open wound of head, part unspecified
0.729 0.271 0.000
S01.3 Open wound of ear
0.727 0.273 0.000
I81 Portal vein thrombosis
0.726 0.274 0.000
I05-I09 Chronic rheumatic heart diseases
0.726 0.274 0.000
H57.9 Disorder of eye and adnexa, unspecified
0.726 0.274 0.000
E27 Other disorders of adrenal gland
0.725 0.275 0.000
L05 Pilonidal cyst
0.725 0.275 0.000
I22.8 Subsequent myocardial infarction of other sites
0.724 0.276 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.724 0.276 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.724 0.276 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.723 0.277 0.000
I84 Haemorrhoids
0.723 0.277 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.722 0.278 0.000
I25.3 Aneurysm of heart
0.722 0.278 0.000
Y57.9 Drug or medicament, unspecified
0.721 0.279 0.000
V80-V89 Other land transport accidents
0.721 0.279 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.720 0.280 0.000
I67.9 Cerebrovascular disease, unspecified
0.719 0.281 0.000
H52.1 Myopia
0.719 0.281 0.000
E16.2 Hypoglycaemia, unspecified
0.719 0.281 0.000
D60-D64 Aplastic and other anaemias
0.718 0.282 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.718 0.282 0.000
I71 Aortic aneurysm and dissection
0.718 0.282 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
L10-L14 Bullous disorders
0.716 0.284 0.000
I25.6 Silent myocardial ischaemia
0.716 0.284 0.000
L04 Acute lymphadenitis
0.715 0.285 0.000
L01 Impetigo
0.715 0.285 0.000
L00 Staphylococcal scalded skin syndrome
0.715 0.285 0.000
Y40.8 Other systemic antibiotics
0.715 0.285 0.000
S08 Traumatic amputation of part of head
0.714 0.285 0.000
S07 Crushing injury of head
0.714 0.285 0.000
S05 Injury of eye and orbit
0.714 0.285 0.000
S04 Injury of cranial nerves
0.714 0.285 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.714 0.285 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.714 0.286 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.714 0.286 0.000
E23 Hypofunction and other disorders of pituitary gland
0.713 0.287 0.000
S80.8 Other superficial injuries of lower leg
0.713 0.287 0.000
O21 Excessive vomiting in pregnancy
0.713 0.287 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.713 0.287 0.000
S01.5 Open wound of lip and oral cavity
0.713 0.287 0.000
S71 Open wound of hip and thigh
0.712 0.287 0.000
S72.2 Subtrochanteric fracture
0.712 0.288 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.710 0.290 0.000
O00-O08 Pregnancy with abortive outcome
0.710 0.290 0.000
D80-D89 Certain disorders involving the immune mechanism
0.709 0.291 0.000
V40-V49 Car occupant injured in transport accident
0.709 0.291 0.000
S06.4 Epidural haemorrhage
0.708 0.292 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.706 0.294 0.000
I88 Nonspecific lymphadenitis
0.706 0.294 0.000
S06.8 Other intracranial injuries
0.703 0.297 0.000
L52 Erythema nodosum
0.702 0.298 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.701 0.299 0.000
H27 Other disorders of lens
0.701 0.299 0.000
E11.5 With peripheral circulatory complications
0.700 0.300 0.000
H26.3 Drug-induced cataract
0.697 0.303 0.000
H26.0 Infantile, juvenile and presenile cataract
0.697 0.303 0.000
S91 Open wound of ankle and foot
0.697 0.303 0.000
S79 Other and unspecified injuries of hip and thigh
0.696 0.304 0.000
I24.1 Dressler's syndrome
0.696 0.304 0.000
H52.0 Hypermetropia
0.696 0.304 0.000
S78 Traumatic amputation of hip and thigh
0.695 0.305 0.000
S77 Crushing injury of hip and thigh
0.695 0.305 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.695 0.305 0.000
S75 Injury of blood vessels at hip and thigh level
0.695 0.305 0.000
S74 Injury of nerves at hip and thigh level
0.695 0.305 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.695 0.305 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.695 0.305 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.695 0.305 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.695 0.305 0.000
H26.2 Complicated cataract
0.694 0.306 0.000
S50-S59 Injuries to the elbow and forearm
0.694 0.306 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.694 0.306 0.000
Y35-Y36 Legal intervention and operations of war
0.694 0.306 0.000
Y10-Y34 Event of undetermined intent
0.694 0.306 0.000
Y00-Y09 Assault
0.694 0.306 0.000
X85-X99 Assault
0.694 0.306 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.694 0.306 0.000
X50-X57 Overexertion, travel and privation
0.694 0.306 0.000
X30-X39 Exposure to forces of nature
0.694 0.306 0.000
X20-X29 Contact with venomous animals and plants
0.694 0.306 0.000
X10-X19 Contact with heat and hot substances
0.694 0.306 0.000
X00-X09 Exposure to smoke, fire and flames
0.694 0.306 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.694 0.306 0.000
W75-W84 Other accidental threats to breathing
0.694 0.306 0.000
W65-W74 Accidental drowning and submersion
0.694 0.306 0.000
W50-W64 Exposure to animate mechanical forces
0.694 0.306 0.000
V98-V99 Other and unspecified transport accidents
0.694 0.306 0.000
V95-V97 Air and space transport accidents
0.694 0.306 0.000
V90-V94 Water transport accidents
0.694 0.306 0.000
V70-V79 Bus occupant injured in transport accident
0.694 0.306 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.694 0.306 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.694 0.306 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.694 0.306 0.000
V01-V09 Pedestrian injured in transport accident
0.694 0.306 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.693 0.307 0.000
Y44 Agents primarily affecting blood constituents
0.693 0.307 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.690 0.310 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.689 0.311 0.000
O20.9 Haemorrhage in early pregnancy, unspecified
0.689 0.311 0.000
S00.5 Superficial injury of lip and oral cavity
0.688 0.312 0.000
S00.4 Superficial injury of ear
0.688 0.312 0.000
I67.2 Cerebral atherosclerosis
0.688 0.312 0.000
Y59 Other and unspecified vaccines and biological substances
0.687 0.312 0.000
Y58 Bacterial vaccines
0.687 0.312 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.687 0.312 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.687 0.312 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.687 0.312 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.687 0.312 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.687 0.312 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.687 0.312 0.000
Y48 Anaesthetics and therapeutic gases
0.687 0.312 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.687 0.312 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.687 0.312 0.000
I82 Other venous embolism and thrombosis
0.687 0.313 0.000
S00.3 Superficial injury of nose
0.687 0.313 0.000
O85-O92 Complications predominantly related to the puerperium
0.686 0.314 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.686 0.314 0.000
S92.7 Multiple fractures of foot
0.684 0.316 0.000
S90.9 Superficial injury of ankle and foot, unspecified
0.684 0.316 0.000
S06.3 Focal brain injury
0.683 0.317 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.682 0.318 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.682 0.318 0.000
V20-V29 Motorcycle rider injured in transport accident
0.681 0.318 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.681 0.319 0.000
A00-A09 Intestinal infectious diseases
0.681 0.319 0.000
I99 Other and unspecified disorders of circulatory system
0.681 0.319 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.681 0.319 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.681 0.319 0.000
I67.5 Moyamoya disease
0.681 0.319 0.000
I67.4 Hypertensive encephalopathy
0.681 0.319 0.000
I67.3 Progressive vascular leukoencephalopathy
0.681 0.319 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.681 0.319 0.000
H40-H42 Glaucoma
0.678 0.322 0.000
S01.7 Multiple open wounds of head
0.678 0.322 0.000
S02.1 Fracture of base of skull
0.678 0.322 0.000
T87 Complications peculiar to reattachment and amputation
0.678 0.322 0.000
I87 Other disorders of veins
0.676 0.324 0.000
S99 Other and unspecified injuries of ankle and foot
0.676 0.324 0.000
S98 Traumatic amputation of ankle and foot
0.676 0.324 0.000
S97 Crushing injury of ankle and foot
0.676 0.324 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.676 0.324 0.000
S95 Injury of blood vessels at ankle and foot level
0.676 0.324 0.000
S94 Injury of nerves at ankle and foot level
0.676 0.324 0.000
S72.9 Fracture of femur, part unspecified
0.676 0.324 0.000
S72.8 Fractures of other parts of femur
0.676 0.324 0.000
S72.7 Multiple fractures of femur
0.676 0.324 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.676 0.324 0.000
S92.4 Fracture of great toe
0.675 0.325 0.000
S02.9 Fracture of skull and facial bones, part unspecified
0.674 0.326 0.000
S00.7 Multiple superficial injuries of head
0.674 0.326 0.000
Y43.3 Other antineoplastic drugs
0.674 0.326 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.672 0.328 0.000
S01.4 Open wound of cheek and temporomandibular area
0.671 0.329 0.000
I86 Varicose veins of other sites
0.671 0.329 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.671 0.329 0.000
I80.8 Phlebitis and thrombophlebitis of other sites
0.671 0.329 0.000
I60.4 Subarachnoid haemorrhage from basilar artery
0.670 0.330 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.669 0.331 0.000
H49.2 Sixth [abducent] nerve palsy
0.669 0.331 0.000
S06.9 Intracranial injury, unspecified
0.668 0.332 0.000
S06.7 Intracranial injury with prolonged coma
0.668 0.332 0.000
S06.1 Traumatic cerebral oedema
0.668 0.332 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.668 0.332 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.667 0.333 0.000
E34 Other endocrine disorders
0.667 0.333 0.000
E32 Diseases of thymus
0.667 0.333 0.000
E31 Polyglandular dysfunction
0.667 0.333 0.000
E30 Disorders of puberty, not elsewhere classified
0.667 0.333 0.000
E26 Hyperaldosteronism
0.667 0.333 0.000
E25 Adrenogenital disorders
0.667 0.333 0.000
E24 Cushing's syndrome
0.667 0.333 0.000
E20 Hypoparathyroidism
0.667 0.333 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.667 0.333 0.000
I84.1 Internal haemorrhoids with other complications
0.667 0.333 0.000
H51 Other disorders of binocular movement
0.666 0.334 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.664 0.336 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.664 0.336 0.000
S92.1 Fracture of talus
0.664 0.336 0.000
E83 Disorders of mineral metabolism
0.664 0.336 0.000
S72.01 Fracture of neck of femur (open)
0.662 0.337 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.660 0.340 0.000
Y40.1 Cefalosporins and other -lactam antibiotics
0.658 0.342 0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.658 0.342 0.000
Y79 Orthopaedic devices associated with adverse incidents
0.656 0.344 0.000
I95.0 Idiopathic hypotension
0.656 0.344 0.000
S88 Traumatic amputation of lower leg
0.656 0.344 0.000
S87 Crushing injury of lower leg
0.656 0.344 0.000
S86 Injury of muscle and tendon at lower leg level
0.656 0.344 0.000
S85 Injury of blood vessels at lower leg level
0.656 0.344 0.000
S84 Injury of nerves at lower leg level
0.656 0.344 0.000
S40 Superficial injury of shoulder and upper arm
0.656 0.344 0.000
L53.9 Erythematous condition, unspecified
0.655 0.345 0.000
E13 Other specified diabetes mellitus
0.654 0.346 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.653 0.347 0.000
S06.20 Diffuse brain injury (without open intracranial wound)
0.651 0.349 0.000
L44 Other papulosquamous disorders
0.651 0.349 0.000
L41 Parapsoriasis
0.651 0.349 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.651 0.349 0.000
L42 Pityriasis rosea
0.651 0.349 0.000
I85.0 Oesophageal varices with bleeding
0.651 0.349 0.000
S02.2 Fracture of nasal bones
0.650 0.349 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.649 0.351 0.000
S92.2 Fracture of other tarsal bone(s)
0.649 0.351 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.648 0.351 0.000
E11.4 With neurological complications
0.647 0.353 0.000
E50-E64 Other nutritional deficiencies
0.646 0.354 0.000
T93 Sequelae of injuries of lower limb
0.645 0.355 0.000
H54.0 Blindness, both eyes
0.645 0.355 0.000
S83.2 Tear of meniscus, current
0.644 0.356 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.643 0.357 0.000
Y43.4 Immunosuppressive agents
0.642 0.358 0.000
X60-X84 Intentional self-harm
0.641 0.358 0.000
I62.1 Nontraumatic extradural haemorrhage
0.641 0.359 0.000
S02.0 Fracture of vault of skull
0.641 0.359 0.000
S72.3 Fracture of shaft of femur
0.641 0.359 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.641 0.359 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.640 0.360 0.000
H54.4 Blindness, one eye
0.640 0.360 0.000
S92.00 Fracture of calcaneus (closed)
0.640 0.360 0.000
I20.1 Angina pectoris with documented spasm
0.639 0.360 0.000
E28 Ovarian dysfunction
0.639 0.361 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.637 0.363 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.636 0.364 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.635 0.365 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.635 0.365 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.635 0.365 0.000
B25-B34 Other viral diseases
0.634 0.366 0.000
O23 Infections of genito-urinary tract in pregnancy
0.634 0.366 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.632 0.367 0.000
S37 Injury of urinary and pelvic organs
0.632 0.367 0.000
S36 Injury of intra-abdominal organs
0.632 0.367 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.632 0.367 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.632 0.367 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.632 0.367 0.000
S31 Open wound of abdomen, lower back and pelvis
0.632 0.367 0.000
H10-H13 Disorders of conjunctiva
0.632 0.368 0.000
Y40.0 Penicillins
0.631 0.369 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.631 0.369 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.631 0.369 0.000
S02.5 Fracture of tooth
0.631 0.369 0.000
E83.5 Disorders of calcium metabolism
0.631 0.369 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.631 0.369 0.000
I72.3 Aneurysm of iliac artery
0.630 0.369 0.000
O24 Diabetes mellitus in pregnancy
0.630 0.370 0.000
D55-D59 Haemolytic anaemias
0.630 0.370 0.000
O21.0 Mild hyperemesis gravidarum
0.630 0.370 0.000
Y45.1 Salicylates
0.629 0.371 0.000
V10-V19 Pedal cyclist injured in transport accident
0.628 0.372 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.628 0.372 0.000
I70.0 Atherosclerosis of aorta
0.627 0.373 0.000
S06.0 Concussion
0.626 0.374 0.000
A15-A19 Tuberculosis
0.626 0.374 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.625 0.375 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.624 0.376 0.000
L40.5 Arthropathic psoriasis
0.624 0.376 0.000
S80.7 Multiple superficial injuries of lower leg
0.621 0.379 0.000
S80.0 Contusion of knee
0.621 0.379 0.000
L54 Erythema in diseases classified elsewhere
0.621 0.379 0.000
L51 Erythema multiforme
0.621 0.379 0.000
O20.0 Threatened abortion
0.621 0.379 0.000
I78 Diseases of capillaries
0.621 0.379 0.000
H52.7 Disorder of refraction, unspecified
0.620 0.380 0.000
H52.6 Other disorders of refraction
0.620 0.380 0.000
H52.5 Disorders of accommodation
0.620 0.380 0.000
H52.4 Presbyopia
0.620 0.380 0.000
H52.3 Anisometropia and aniseikonia
0.620 0.380 0.000
D62 Acute posthaemorrhagic anaemia
0.620 0.380 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.620 0.380 0.000
E21.4 Other specified disorders of parathyroid gland
0.620 0.380 0.000
E21.2 Other hyperparathyroidism
0.620 0.380 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.620 0.380 0.000
D61 Other aplastic anaemias
0.619 0.381 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.618 0.381 0.000
H35 Other retinal disorders
0.618 0.382 0.000
I84.2 Internal haemorrhoids without complication
0.618 0.382 0.000
S89 Other and unspecified injuries of lower leg
0.617 0.382 0.000
E15 Nondiabetic hypoglycaemic coma
0.617 0.383 0.000
Y57.8 Other drugs and medicaments
0.617 0.383 0.000
Y57.7 Vitamins, not elsewhere classified
0.617 0.383 0.000
Y57.6 Other diagnostic agents
0.617 0.383 0.000
Y57.4 Pharmaceutical excipients
0.617 0.383 0.000
Y57.3 Alcohol deterrents
0.617 0.383 0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified
0.617 0.383 0.000
Y57.1 Lipotropic drugs
0.617 0.383 0.000
Y57.0 Appetite depressants [anorectics]
0.617 0.383 0.000
S92.9 Fracture of foot, unspecified
0.617 0.383 0.000
S92.5 Fracture of other toe
0.617 0.383 0.000
T66-T78 Other and unspecified effects of external causes
0.617 0.383 0.000
E12 Malnutrition-related diabetes mellitus
0.616 0.384 0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
0.616 0.384 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.616 0.384 0.000
E65-E68 Obesity and other hyperalimentation
0.616 0.384 0.000
E29 Testicular dysfunction
0.615 0.385 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.615 0.385 0.000
E88 Other metabolic disorders
0.615 0.385 0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system
0.615 0.385 0.000
Y52.8 Antivaricose drugs, including sclerosing agents
0.615 0.385 0.000
Y52.7 Peripheral vasodilators
0.615 0.385 0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.615 0.385 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.615 0.385 0.000
Y52.1 Calcium-channel blockers
0.615 0.385 0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action
0.615 0.385 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.613 0.387 0.000
S32.1 Fracture of sacrum
0.613 0.387 0.000
I74 Arterial embolism and thrombosis
0.613 0.387 0.000
T82.3 Mechanical complication of other vascular grafts
0.613 0.387 0.000
T98 Sequelae of other and unspecified effects of external causes
0.613 0.387 0.000
O04 Medical abortion
0.613 0.387 0.000
T90 Sequelae of injuries of head
0.607 0.393 0.000
L43.9 Lichen planus, unspecified
0.607 0.393 0.000
Y85 Sequelae of transport accidents
0.607 0.393 0.000
S02.3 Fracture of orbital floor
0.606 0.394 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.606 0.394 0.000
S20 Superficial injury of thorax
0.604 0.396 0.000
I07 Rheumatic tricuspid valve diseases
0.604 0.396 0.000
S02.8 Fractures of other skull and facial bones
0.603 0.397 0.000
S02.7 Multiple fractures involving skull and facial bones
0.603 0.397 0.000
S30.0 Contusion of lower back and pelvis
0.602 0.397 0.000
B35-B49 Mycoses
0.602 0.398 0.000
T88.4 Failed or difficult intubation
0.602 0.398 0.000
H57.8 Other specified disorders of eye and adnexa
0.602 0.398 0.000
L03.3 Cellulitis of trunk
0.601 0.399 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.601 0.399 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.600 0.400 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.600 0.400 0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified
0.599 0.401 0.000
W25 Contact with sharp glass
0.598 0.402 0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft
0.598 0.402 0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract
0.598 0.402 0.000
T83.2 Mechanical complication of graft of urinary organ
0.598 0.402 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.597 0.403 0.000
H57.0 Anomalies of pupillary function
0.595 0.405 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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