TreeWAS – Variant ID: rs10971170

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
I30-I52 Other forms of heart disease	0.978	0.022
Chapter IX Diseases of the circulatory system	0.975	0.025
# Top node	0.972	0.028
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.972	0.028
I50 Heart failure	0.970	0.030
I51 Complications and ill-defined descriptions of heart disease	0.963	0.037
I50.0 Congestive heart failure	0.947	0.053
I42 Cardiomyopathy	0.945	0.055
I51.7 Cardiomegaly	0.936	0.064
Chapter XX External causes of morbidity and mortality	0.934	0.066
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.904	0.096
Chapter II Neoplasms	0.897	0.103
S00-S09 Injuries to the head	0.896	0.104
C44 Other malignant neoplasms of skin	0.894	0.106
C43-C44 Melanoma and other malignant neoplasms of skin	0.894	0.106
I51.9 Heart disease, unspecified	0.891	0.109
Chapter XIV Diseases of the genitourinary system	0.891	0.109
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.880	0.120
S20-S29 Injuries to the thorax	0.880	0.120
N17-N19 Renal failure	0.880	0.120
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.870	0.130
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.870	0.130
C44.2 Skin of ear and external auricular canal	0.868	0.132
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.864	0.136
T79-T79 Certain early complications of trauma	0.860	0.140
N18 Chronic renal failure	0.857	0.143
I42.0 Dilated cardiomyopathy	0.856	0.144
S90-S99 Injuries to the ankle and foot	0.854	0.146
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.847	0.153
I42.9 Cardiomyopathy, unspecified	0.846	0.154
I05-I09 Chronic rheumatic heart diseases	0.846	0.154
I50.1 Left ventricular failure	0.844	0.156
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.833	0.167
I50.9 Heart failure, unspecified	0.825	0.175
N10-N16 Renal tubulo-interstitial diseases	0.821	0.179
I38 Endocarditis, valve unspecified	0.821	0.179
N25-N29 Other disorders of kidney and ureter	0.821	0.179
C44.1 Skin of eyelid, including canthus	0.811	0.189
S01 Open wound of head	0.810	0.190
C44.0 Skin of lip	0.808	0.192
Y86 Sequelae of other accidents	0.803	0.197
S22 Fracture of rib(s), sternum and thoracic spine	0.801	0.199
I80 Phlebitis and thrombophlebitis	0.800	0.200
S50-S59 Injuries to the elbow and forearm	0.798	0.202
C44.5 Skin of trunk	0.797	0.203
S60-S69 Injuries to the wrist and hand	0.797	0.203
Q60-Q64 Congenital malformations of the urinary system	0.795	0.205
C15-C26 Malignant neoplasms of digestive organs	0.794	0.206
T85 Complications of other internal prosthetic devices, implants and grafts	0.794	0.206
N19 Unspecified renal failure	0.793	0.207
I70-I79 Diseases of arteries, arterioles and capillaries	0.791	0.209
S70-S79 Injuries to the hip and thigh	0.789	0.211
S10-S19 Injuries to the neck	0.782	0.218
T79 Certain early complications of trauma, not elsewhere classified	0.780	0.220
I33 Acute and subacute endocarditis	0.778	0.221
I31 Other diseases of pericardium	0.777	0.223
Chapter I Certain infectious and parasitic diseases	0.776	0.224
D00-D09 In situ neoplasms	0.773	0.227
C15 Malignant neoplasm of oesophagus	0.771	0.229
N28 Other disorders of kidney and ureter, not elsewhere classified	0.770	0.230
Y45.0 Opioids and related analgesics	0.769	0.231
N18.5 Chronic kidney disease, stage 5	0.769	0.231
I45 Other conduction disorders	0.758	0.242
Chapter XXI Factors influencing health status and contact with health services	0.757	0.243
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.755	0.245
C44.3 Skin of other and unspecified parts of face	0.753	0.247
I51.0 Cardiac septal defect, acquired	0.750	0.250
I07 Rheumatic tricuspid valve diseases	0.748	0.252
I44 Atrioventricular and left bundle-branch block	0.745	0.255
V10-V19 Pedal cyclist injured in transport accident	0.744	0.256
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.744	0.256
X20-X29 Contact with venomous animals and plants	0.742	0.258
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.739	0.261
N18.2 Chronic kidney disease, stage 2	0.739	0.261
I42.1 Obstructive hypertrophic cardiomyopathy	0.737	0.263
T15-T19 Effects of foreign body entering through natural orifice	0.734	0.266
N00-N08 Glomerular diseases	0.734	0.266
I42.8 Other cardiomyopathies	0.730	0.270
I83 Varicose veins of lower extremities	0.725	0.275
Z00-Z13 Persons encountering health services for examination and investigation	0.725	0.275
X60-X84 Intentional self-harm	0.723	0.277
Y40 Systemic antibiotics	0.723	0.277
I71 Aortic aneurysm and dissection	0.722	0.278
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.721	0.279
T91 Sequelae of injuries of neck and trunk	0.720	0.280
N70-N77 Inflammatory diseases of female pelvic organs	0.719	0.281
N18.0 End-stage renal disease	0.719	0.281
S99 Other and unspecified injuries of ankle and foot	0.715	0.285
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.714	0.286
N28.1 Cyst of kidney, acquired	0.713	0.287
C15.5 Lower third of oesophagus	0.713	0.287
S62 Fracture at wrist and hand level	0.713	0.287
Q50-Q56 Congenital malformations of genital organs	0.711	0.289
S01.8 Open wound of other parts of head	0.711	0.289
S06 Intracranial injury	0.707	0.293
N18.9 Chronic renal failure, unspecified	0.706	0.294
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.706	0.294
B95-B98 Bacterial, viral and other infectious agents	0.706	0.294
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.705	0.295
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent	0.703	0.297
T85.2 Mechanical complication of intraocular lens	0.703	0.297
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.703	0.297
I30 Acute pericarditis	0.702	0.298
I86 Varicose veins of other sites	0.701	0.298
T90 Sequelae of injuries of head	0.701	0.299
I52 Other heart disorders in diseases classified elsewhere	0.701	0.299
I48 Atrial fibrillation and flutter	0.701	0.299
I43 Cardiomyopathy in diseases classified elsewhere	0.701	0.299
I41 Myocarditis in diseases classified elsewhere	0.701	0.299
I40 Acute myocarditis	0.701	0.299
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.701	0.299
I37 Pulmonary valve disorders	0.701	0.299
I36 Nonrheumatic tricuspid valve disorders	0.701	0.299
I32 Pericarditis in diseases classified elsewhere	0.701	0.299
S02 Fracture of skull and facial bones	0.700	0.300
Chapter XXII Codes for special purposes	0.699	0.300
Z13 Special screening examination for other diseases and disorders	0.699	0.301
I00-I02 Acute rheumatic fever	0.699	0.301
Chapter XVI Certain conditions originating in the perinatal period	0.697	0.303
T33-T35 Frostbite	0.697	0.303
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.697	0.303
T26-T28 Burns and corrosions confined to eye and internal organs	0.697	0.303
T20-T25 Burns and corrosions of external body surface, specified by site	0.697	0.303
T00-T07 Injuries involving multiple body regions	0.697	0.303
S01.3 Open wound of ear	0.692	0.308
Z03 Medical observation and evaluation for suspected diseases and conditions	0.691	0.309
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.691	0.309
I51.6 Cardiovascular disease, unspecified	0.690	0.310
I51.5 Myocardial degeneration	0.690	0.310
I51.4 Myocarditis, unspecified	0.690	0.310
I51.3 Intracardiac thrombosis, not elsewhere classified	0.690	0.310
I51.2 Rupture of papillary muscle, not elsewhere classified	0.690	0.310
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.690	0.310
D03 Melanoma in situ	0.689	0.311
Chapter X Diseases of the respiratory system	0.689	0.311
I46 Cardiac arrest	0.687	0.313
S05 Injury of eye and orbit	0.687	0.313
T85.4 Mechanical complication of breast prosthesis and implant	0.687	0.313
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.684	0.316
Q00-Q07 Congenital malformations of the nervous system	0.683	0.317
T86 Failure and rejection of transplanted organs and tissues	0.681	0.319
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.681	0.319
S09 Other and unspecified injuries of head	0.680	0.320
C15.9 Oesophagus, unspecified	0.680	0.320
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.679	0.321
I07.1 Tricuspid insufficiency	0.678	0.321
I42.7 Cardiomyopathy due to drugs and other external agents	0.677	0.323
I42.6 Alcoholic cardiomyopathy	0.677	0.323
I42.5 Other restrictive cardiomyopathy	0.677	0.323
I42.4 Endocardial fibroelastosis	0.677	0.323
I42.3 Endomyocardial (eosinophilic) disease	0.677	0.323
I60-I69 Cerebrovascular diseases	0.676	0.323
T92 Sequelae of injuries of upper limb	0.676	0.324
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.676	0.324
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.676	0.324
N13 Obstructive and reflux uropathy	0.676	0.324
Y60-Y69 Misadventures to patients during surgical and medical care	0.675	0.324
N28.9 Disorder of kidney and ureter, unspecified	0.675	0.325
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.675	0.325
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.675	0.325
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.675	0.325
Chapter VII Diseases of the eye and adnexa	0.674	0.326
J09-J18 Influenza and pneumonia	0.672	0.328
Y41 Other systemic anti-infectives and antiparasitics	0.672	0.328
C25 Malignant neoplasm of pancreas	0.670	0.330
Y35-Y36 Legal intervention and operations of war	0.669	0.330
Y10-Y34 Event of undetermined intent	0.669	0.330
Y00-Y09 Assault	0.669	0.330
X85-X99 Assault	0.669	0.330
X58-X59 Accidental exposure to other and unspecified factors	0.669	0.330
X50-X57 Overexertion, travel and privation	0.669	0.330
X40-X49 Accidental poisoning by and exposure to noxious substances	0.669	0.330
X30-X39 Exposure to forces of nature	0.669	0.330
X10-X19 Contact with heat and hot substances	0.669	0.330
X00-X09 Exposure to smoke, fire and flames	0.669	0.330
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.669	0.330
W75-W84 Other accidental threats to breathing	0.669	0.330
W65-W74 Accidental drowning and submersion	0.669	0.330
W50-W64 Exposure to animate mechanical forces	0.669	0.330
V98-V99 Other and unspecified transport accidents	0.669	0.330
V95-V97 Air and space transport accidents	0.669	0.330
V90-V94 Water transport accidents	0.669	0.330
V70-V79 Bus occupant injured in transport accident	0.669	0.330
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.669	0.330
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.669	0.330
V40-V49 Car occupant injured in transport accident	0.669	0.330
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.669	0.330
V01-V09 Pedestrian injured in transport accident	0.669	0.330
Q38-Q45 Other congenital malformations of the digestive system	0.669	0.331
N11 Chronic tubulo-interstitial nephritis	0.669	0.331
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.669	0.331
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis	0.667	0.333
I44.2 Atrioventricular block, complete	0.667	0.333
S90 Superficial injury of ankle and foot	0.664	0.335
I77 Other disorders of arteries and arterioles	0.664	0.336
Q63 Other congenital malformations of kidney	0.663	0.337
I82 Other venous embolism and thrombosis	0.663	0.337
I85 Oesophageal varices	0.662	0.338
Q61 Cystic kidney disease	0.662	0.338
D37-D48 Neoplasms of uncertain or unknown behaviour	0.662	0.338
N18.3 Chronic kidney disease, stage 3	0.661	0.339
N99-N99 Other disorders of the genitourinary system	0.661	0.339
V20-V29 Motorcycle rider injured in transport accident	0.660	0.340
C44.9 Malignant neoplasm of skin, unspecified	0.659	0.341
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.658	0.342
S27 Injury of other and unspecified intrathoracic organs	0.658	0.342
Z03.4 Observation for suspected myocardial infarction	0.658	0.342
J18 Pneumonia, organism unspecified	0.657	0.343
Y45.2 Propionic acid derivatives	0.657	0.343
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.655	0.345
S80-S89 Injuries to the knee and lower leg	0.655	0.345
A30-A49 Other bacterial diseases	0.654	0.346
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.654	0.346
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.653	0.347
C44.4 Skin of scalp and neck	0.653	0.347
V80-V89 Other land transport accidents	0.651	0.349
Z70-Z76 Persons encountering health services in other circumstances	0.650	0.350
S20 Superficial injury of thorax	0.649	0.350
S01.1 Open wound of eyelid and periocular area	0.650	0.350
T79.8 Other early complications of trauma	0.649	0.351
J18.1 Lobar pneumonia, unspecified	0.649	0.351
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.648	0.352
Q80-Q89 Other congenital malformations	0.648	0.352
Q35-Q37 Cleft lip and cleft palate	0.648	0.352
Q30-Q34 Congenital malformations of the respiratory system	0.648	0.352
T79.3 Post-traumatic wound infection, not elsewhere classified	0.647	0.353
S72 Fracture of femur	0.647	0.353
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.645	0.355
I31.3 Pericardial effusion (noninflammatory)	0.645	0.355
S22.4 Multiple fractures of ribs	0.643	0.357
C40-C41 Malignant neoplasms of bone and articular cartilage	0.643	0.357
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.643	0.357
S08 Traumatic amputation of part of head	0.642	0.358
S07 Crushing injury of head	0.642	0.358
S04 Injury of cranial nerves	0.642	0.358
S03 Dislocation, sprain and strain of joints and ligaments of head	0.642	0.358
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.642	0.358
C44.8 Overlapping lesion of skin	0.641	0.359
S22.3 Fracture of rib	0.639	0.361
N72 Inflammatory disease of cervix uteri	0.637	0.363
N10 Acute tubulo-interstitial nephritis	0.636	0.364
I33.0 Acute and subacute infective endocarditis	0.636	0.364
S59 Other and unspecified injuries of forearm	0.635	0.365
I42.2 Other hypertrophic cardiomyopathy	0.634	0.365
S01.2 Open wound of nose	0.634	0.366
C16 Malignant neoplasm of stomach	0.633	0.367
S22.1 Multiple fractures of thoracic spine	0.633	0.367
T88 Other complications of surgical and medical care, not elsewhere classified	0.632	0.367
I27 Other pulmonary heart diseases	0.632	0.368
Y59 Other and unspecified vaccines and biological substances	0.631	0.369
Y58 Bacterial vaccines	0.631	0.369
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.631	0.369
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.631	0.369
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.631	0.369
Y53 Agents primarily affecting the gastro-intestinal system	0.631	0.369
Y50 Central nervous system stimulants, not elsewhere classified	0.631	0.369
Y49 Psychotropic drugs, not elsewhere classified	0.631	0.369
Y48 Anaesthetics and therapeutic gases	0.631	0.369
Y47 Sedatives, hypnotics and antianxiety drugs	0.631	0.369
Y46 Antiepileptics and anti-Parkinsonism drugs	0.631	0.369
S29 Other and unspecified injuries of thorax	0.631	0.369
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.631	0.369
S26 Injury of heart	0.631	0.369
S25 Injury of blood vessels of thorax	0.631	0.369
S24 Injury of nerves and spinal cord at thorax level	0.631	0.369
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.631	0.369
S21 Open wound of thorax	0.631	0.369
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters	0.631	0.369
D07 Carcinoma in situ of other and unspecified genital organs	0.627	0.372
S22.2 Fracture of sternum	0.627	0.373
J20-J22 Other acute lower respiratory infections	0.627	0.373
Y85 Sequelae of transport accidents	0.626	0.374
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.626	0.374
S40-S49 Injuries to the shoulder and upper arm	0.625	0.375
Y89 Sequelae of other external causes	0.624	0.376
Y88 Sequelae of surgical and medical care as external cause	0.624	0.376
I88 Nonspecific lymphadenitis	0.623	0.376
Z13.9 Special screening examination, unspecified	0.623	0.377
T83.1 Mechanical complication of other urinary devices and implants	0.623	0.377
C15.4 Middle third of oesophagus	0.623	0.377
I69 Sequelae of cerebrovascular disease	0.622	0.378
Z13.1 Special screening examination for diabetes mellitus	0.621	0.379
S62.6 Fracture of other finger	0.621	0.379
T98 Sequelae of other and unspecified effects of external causes	0.619	0.381
T95 Sequelae of burns, corrosions and frostbite	0.619	0.381
T94 Sequelae of injuries involving multiple and unspecified body regions	0.619	0.381
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.619	0.381
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.619	0.381
T79.7 Traumatic subcutaneous emphysema	0.618	0.382
Q20-Q28 Congenital malformations of the circulatory system	0.618	0.382
N17 Acute renal failure	0.617	0.383
Y57 Other and unspecified drugs and medicaments	0.615	0.385
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.615	0.385
T91.9 Sequelae of unspecified injury of neck and trunk	0.615	0.385
S99.9 Unspecified injury of ankle and foot	0.614	0.385
N18.8 Other chronic renal failure	0.614	0.386
N18.1 Chronic kidney disease, stage 1	0.614	0.386
Z03.1 Observation for suspected malignant neoplasm	0.614	0.386
I05 Rheumatic mitral valve diseases	0.613	0.387
S98 Traumatic amputation of ankle and foot	0.612	0.387
S97 Crushing injury of ankle and foot	0.612	0.387
S96 Injury of muscle and tendon at ankle and foot level	0.612	0.387
S95 Injury of blood vessels at ankle and foot level	0.612	0.387
S94 Injury of nerves at ankle and foot level	0.612	0.387
S91 Open wound of ankle and foot	0.612	0.387
Z13.6 Special screening examination for cardiovascular disorders	0.613	0.387
I08 Multiple valve diseases	0.612	0.388
S64 Injury of nerves at wrist and hand level	0.611	0.388
Chapter XII Diseases of the skin and subcutaneous tissue	0.610	0.390
V18 Pedal cyclist injured in noncollision transport accident	0.609	0.391
S68 Traumatic amputation of wrist and hand	0.608	0.392
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.607	0.393
Y45.8 Other analgesics and antipyretics	0.607	0.393
Y45.5 4-Aminophenol derivatives	0.607	0.393
Y45.4 Antirheumatics	0.607	0.393
Y45.1 Salicylates	0.607	0.393
I87 Other disorders of veins	0.606	0.393
I09 Other rheumatic heart diseases	0.606	0.394
I06 Rheumatic aortic valve diseases	0.606	0.394
Y44 Agents primarily affecting blood constituents	0.606	0.394
X23 Contact with hornets, wasps and bees	0.605	0.395
I44.0 Atrioventricular block, first degree	0.604	0.396
D03.5 Melanoma in situ of trunk	0.603	0.397
T93 Sequelae of injuries of lower limb	0.603	0.397
S71 Open wound of hip and thigh	0.603	0.397
Y52 Agents primarily affecting the cardiovascular system	0.603	0.397
C81 Hodgkin's disease	0.602	0.398
Z03.9 Observation for suspected disease or condition, unspecified	0.602	0.398
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.601	0.399
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.601	0.399
S10 Superficial injury of neck	0.601	0.399
S61 Open wound of wrist and hand	0.599	0.401
S93.1 Dislocation of toe(s)	0.598	0.402
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.598	0.402
S22.0 Fracture of thoracic vertebra	0.598	0.402
S52 Fracture of forearm	0.597	0.403
T87 Complications peculiar to reattachment and amputation	0.597	0.403
S62.5 Fracture of thumb	0.597	0.403
I45.8 Other specified conduction disorders	0.596	0.404
I45.9 Conduction disorder, unspecified	0.595	0.405
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.593	0.406
Z01.8 Other specified special examinations	0.593	0.407
N75 Diseases of Bartholin's gland	0.592	0.408
S19 Other and unspecified injuries of neck	0.592	0.408
I95-I99 Other and unspecified disorders of the circulatory system	0.590	0.410
B65-B83 Helminthiases	0.589	0.411
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.589	0.411
N15 Other renal tubulo-interstitial diseases	0.589	0.411
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.589	0.411
N29 Other disorders of kidney and ureter in diseases classified elsewhere	0.588	0.411
N27 Small kidney of unknown cause	0.588	0.411
N25 Disorders resulting from impaired renal tubular function	0.588	0.411
N26 Unspecified contracted kidney	0.588	0.411
S12 Fracture of neck	0.587	0.412
N03 Chronic nephritic syndrome	0.587	0.413
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere	0.586	0.414
I45.3 Trifascicular block	0.586	0.414
Y87.1 Sequelae of assault	0.584	0.416
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.584	0.416
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.583	0.416
J22 Unspecified acute lower respiratory infection	0.583	0.417
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.582	0.418
S01.7 Multiple open wounds of head	0.581	0.419
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.581	0.419
T80 Complications following infusion, transfusion and therapeutic injection	0.580	0.419
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.580	0.420
T90.5 Sequelae of intracranial injury	0.579	0.420
I74 Arterial embolism and thrombosis	0.579	0.421
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.578	0.422
I72 Other aneurysm	0.577	0.423
J18.0 Bronchopneumonia, unspecified	0.577	0.423
D09 Carcinoma in situ of other and unspecified sites	0.576	0.424
Z04 Examination and observation for other reasons	0.574	0.426
S22.9 Fracture of bony thorax, part unspecified	0.574	0.426
S22.8 Fracture of other parts of bony thorax	0.574	0.426
S22.5 Flail chest	0.574	0.426
Y40.3 Macrolides	0.574	0.426
C21 Malignant neoplasm of anus and anal canal	0.574	0.426
W00-W19 Falls	0.574	0.426
I71.3 Abdominal aortic aneurysm, ruptured	0.574	0.426
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.573	0.426
S01.4 Open wound of cheek and temporomandibular area	0.573	0.427
S58 Traumatic amputation of forearm	0.572	0.427
S57 Crushing injury of forearm	0.572	0.427
S56 Injury of muscle and tendon at forearm level	0.572	0.427
S55 Injury of blood vessels at forearm level	0.572	0.427
S54 Injury of nerves at forearm level	0.572	0.427
C91 Lymphoid leukaemia	0.572	0.428
Y40.9 Systemic antibiotic, unspecified	0.572	0.428
S65 Injury of blood vessels at wrist and hand level	0.571	0.428
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters	0.571	0.429
Q64 Other congenital malformations of urinary system	0.570	0.430
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.570	0.430
Q60 Renal agenesis and other reduction defects of kidney	0.570	0.430
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.570	0.430
C17 Malignant neoplasm of small intestine	0.570	0.430
C23 Malignant neoplasm of gallbladder	0.570	0.430
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.569	0.430
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.569	0.430
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.569	0.430
Q63.0 Accessory kidney	0.569	0.431
S01.9 Open wound of head, part unspecified	0.569	0.431
S70 Superficial injury of hip and thigh	0.567	0.433
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.567	0.433
S80 Superficial injury of lower leg	0.567	0.433
C26 Malignant neoplasm of other and ill-defined digestive organs	0.567	0.433
S02.5 Fracture of tooth	0.567	0.433
S78 Traumatic amputation of hip and thigh	0.565	0.434
S77 Crushing injury of hip and thigh	0.565	0.434
S76 Injury of muscle and tendon at hip and thigh level	0.565	0.434
S75 Injury of blood vessels at hip and thigh level	0.565	0.434
S74 Injury of nerves at hip and thigh level	0.565	0.434
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.565	0.434
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.565	0.434
I77.9 Disorder of arteries and arterioles, unspecified	0.565	0.435
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.565	0.435
Q18 Other congenital malformations of face and neck	0.564	0.435
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.564	0.436
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.564	0.436
T86.1 Kidney transplant failure and rejection	0.564	0.436
T18 Foreign body in alimentary tract	0.564	0.436
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.564	0.436
S50 Superficial injury of forearm	0.563	0.437
S01.5 Open wound of lip and oral cavity	0.561	0.439
S17 Crushing injury of neck	0.561	0.439
S15 Injury of blood vessels at neck level	0.561	0.439
S14 Injury of nerves and spinal cord at neck level	0.561	0.439
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.561	0.439
S11 Open wound of neck	0.561	0.439
S18 Traumatic amputation at neck level	0.561	0.439
S16 Injury of muscle and tendon at neck level	0.561	0.439
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.560	0.440
Z75 Problems related to medical facilities and other health care	0.560	0.440
N08 Glomerular disorders in diseases classified elsewhere	0.559	0.441
Z01.6 Radiological examination, not elsewhere classified	0.559	0.441
T79.9 Unspecified early complication of trauma	0.559	0.441
T79.6 Traumatic ischaemia of muscle	0.559	0.441
T79.5 Traumatic anuria	0.559	0.441
T79.4 Traumatic shock	0.559	0.441
T79.2 Traumatic secondary and recurrent haemorrhage	0.559	0.441
T79.1 Fat embolism (traumatic)	0.559	0.441
T79.0 Air embolism (traumatic)	0.559	0.441
T66-T78 Other and unspecified effects of external causes	0.558	0.441
I33.9 Acute endocarditis, unspecified	0.558	0.442
C44.6 Skin of upper limb, including shoulder	0.557	0.443
I31.8 Other specified diseases of pericardium	0.557	0.443
I31.2 Haemopericardium, not elsewhere classified	0.557	0.443
I31.1 Chronic constrictive pericarditis	0.557	0.443
I31.0 Chronic adhesive pericarditis	0.557	0.443
C92 Myeloid leukaemia	0.556	0.444
B99-B99 Other infectious diseases	0.556	0.444
B90-B94 Sequelae of infectious and parasitic diseases	0.556	0.444
B85-B89 Pediculosis, acariasis and other infestations	0.556	0.444
B50-B64 Protozoal diseases	0.556	0.444
B20-B24 Human immunodeficiency virus [HIV] disease	0.556	0.444
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.556	0.444
A75-A79 Rickettsioses	0.556	0.444
A70-A74 Other diseases caused by chlamydiae	0.556	0.444
A65-A69 Other spirochaetal diseases	0.556	0.444
A20-A28 Certain zoonotic bacterial diseases	0.556	0.444
A15-A19 Tuberculosis	0.556	0.444
S92 Fracture of foot, except ankle	0.554	0.446
D02 Carcinoma in situ of middle ear and respiratory system	0.554	0.446
D01 Carcinoma in situ of other and unspecified digestive organs	0.554	0.446
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.554	0.446
I86.1 Scrotal varices	0.554	0.446
C64-C68 Malignant neoplasms of urinary tract	0.554	0.446
Z03.3 Observation for suspected nervous system disorder	0.554	0.446
C15.8 Overlapping lesion of oesophagus	0.553	0.447
C15.3 Upper third of oesophagus	0.553	0.447
C15.2 Abdominal part of oesophagus	0.553	0.447
C15.1 Thoracic part of oesophagus	0.553	0.447
C15.0 Cervical part of oesophagus	0.553	0.447
N05 Unspecified nephritic syndrome	0.553	0.447
N28.0 Ischaemia and infarction of kidney	0.552	0.447
I45.5 Other specified heart block	0.552	0.448
H30-H36 Disorders of choroid and retina	0.552	0.448
H46-H48 Disorders of optic nerve and visual pathways	0.552	0.448
I83.1 Varicose veins of lower extremities with inflammation	0.552	0.448
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.552	0.448
I80.8 Phlebitis and thrombophlebitis of other sites	0.551	0.449
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0.550	0.450
C25.9 Pancreas, unspecified	0.550	0.450
Chapter V Mental and behavioural disorders	0.549	0.451
S62.8 Fracture of other and unspecified parts of wrist and hand	0.548	0.452
I44.1 Atrioventricular block, second degree	0.548	0.452
X78 Intentional self-harm by sharp object	0.548	0.452
T92.0 Sequelae of open wound of upper limb	0.546	0.453
A50-A64 Infections with a predominantly sexual mode of transmission	0.546	0.454
L00-L08 Infections of the skin and subcutaneous tissue	0.546	0.454
D03.7 Melanoma in situ of lower limb, including hip	0.545	0.455
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.545	0.455
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.545	0.455
I46.0 Cardiac arrest with successful resuscitation	0.544	0.456
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system	0.544	0.456
T90.4 Sequelae of injury of eye and orbit	0.544	0.456
B15-B19 Viral hepatitis	0.544	0.456
I45.4 Nonspecific intraventricular block	0.543	0.457
I45.2 Bifascicular block	0.543	0.457
I45.0 Right fascicular block	0.543	0.457

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations