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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs10973964
log Bayes Factor = 14.244
Chromosome 9   position 38,669,362  (GRCh37) Explore rs10973964 on Ensembl!
Variant rs10973964 is part of Cluster X0180

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
1.000 0.000 0.000
C50-C50 Malignant neoplasm of breast
0.999 0.001 0.000
C50 Malignant neoplasm of breast
0.999 0.001 0.000
Chapter X Diseases of the respiratory system
0.996 0.004 0.000
Chapter VII Diseases of the eye and adnexa
0.995 0.005 0.000
Z51 Other medical care
0.994 0.006 0.000
J30-J39 Other diseases of upper respiratory tract
0.992 0.008 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.990 0.010 0.000
Z51.5 Palliative care
0.990 0.010 0.000
Chapter XIV Diseases of the genitourinary system
0.978 0.022 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.976 0.024 0.000
J32 Chronic sinusitis
0.974 0.026 0.000
N60-N64 Disorders of breast
0.969 0.031 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.969 0.031 0.000
Z42 Follow-up care involving plastic surgery
0.969 0.031 0.000
H30-H36 Disorders of choroid and retina
0.966 0.034 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.966 0.034 0.000
S60-S69 Injuries to the wrist and hand
0.962 0.038 0.000
N63 Unspecified lump in breast
0.958 0.042 0.000
Chapter I Certain infectious and parasitic diseases
0.958 0.042 0.000
J32.9 Chronic sinusitis, unspecified
0.946 0.054 0.000
S00-S09 Injuries to the head
0.944 0.056 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.943 0.057 0.000
C50.9 Breast, unspecified
0.943 0.057 0.000
E70-E90 Metabolic disorders
0.943 0.057 0.000
Z47 Other orthopaedic follow-up care
0.941 0.059 0.000
C50.8 Overlapping lesion of breast
0.939 0.061 0.000
Z42.1 Follow-up care involving plastic surgery of breast
0.933 0.067 0.000
Z01.8 Other specified special examinations
0.932 0.068 0.000
N40-N51 Diseases of male genital organs
0.931 0.069 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.928 0.072 0.000
C50.5 Lower-outer quadrant of breast
0.926 0.074 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.922 0.078 0.000
S01 Open wound of head
0.921 0.079 0.000
H35 Other retinal disorders
0.919 0.081 0.000
E65-E68 Obesity and other hyperalimentation
0.918 0.082 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.915 0.085 0.000
E20-E35 Disorders of other endocrine glands
0.915 0.085 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.914 0.086 0.000
B95-B98 Bacterial, viral and other infectious agents
0.910 0.090 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.906 0.094 0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device
0.903 0.097 0.000
H10-H13 Disorders of conjunctiva
0.902 0.098 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.902 0.098 0.000
N17-N19 Renal failure
0.899 0.101 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.896 0.104 0.000
T81 Complications of procedures, not elsewhere classified
0.893 0.107 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.892 0.108 0.000
S61 Open wound of wrist and hand
0.889 0.111 0.000
E78.5 Hyperlipidaemia, unspecified
0.888 0.112 0.000
S01.0 Open wound of scalp
0.885 0.115 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.878 0.122 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.871 0.129 0.000
J95-J99 Other diseases of the respiratory system
0.869 0.131 0.000
H35.8 Other specified retinal disorders
0.867 0.133 0.000
E66 Obesity
0.867 0.133 0.000
C50.4 Upper-outer quadrant of breast
0.866 0.134 0.000
H53-H54 Visual disturbances and blindness
0.866 0.134 0.000
Z13 Special screening examination for other diseases and disorders
0.860 0.140 0.000
N43 Hydrocele and spermatocele
0.856 0.144 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.855 0.145 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.854 0.146 0.000
Chapter V Mental and behavioural disorders
0.850 0.150 0.000
H50 Other strabismus
0.850 0.150 0.000
C50.1 Central portion of breast
0.849 0.151 0.000
C51-C58 Malignant neoplasms of female genital organs
0.848 0.152 0.000
C50.2 Upper-inner quadrant of breast
0.847 0.153 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.846 0.154 0.000
Chapter VIII Diseases of the ear and mastoid process
0.845 0.155 0.000
N48 Other disorders of penis
0.845 0.155 0.000
S61.0 Open wound of finger(s) without damage to nail
0.840 0.160 0.000
C71 Malignant neoplasm of brain
0.836 0.164 0.000
Z51.0 Radiotherapy session
0.836 0.164 0.000
Z41 Procedures for purposes other than remedying health state
0.836 0.164 0.000
N45 Orchitis and epididymitis
0.836 0.164 0.000
Chapter XXII Codes for special purposes
0.835 0.165 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.835 0.165 0.000
S80-S89 Injuries to the knee and lower leg
0.833 0.167 0.000
E66.8 Other obesity
0.830 0.170 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.828 0.172 0.000
E83 Disorders of mineral metabolism
0.823 0.177 0.000
J32.4 Chronic pansinusitis
0.819 0.181 0.000
J38.1 Polyp of vocal cord and larynx
0.819 0.181 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.818 0.182 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.818 0.182 0.000
T79-T79 Certain early complications of trauma
0.816 0.184 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.815 0.185 0.000
H36 Retinal disorders in diseases classified elsewhere
0.814 0.186 0.000
J33 Nasal polyp
0.812 0.188 0.000
J38.7 Other diseases of larynx
0.812 0.188 0.000
Z49 Care involving dialysis
0.809 0.190 0.000
J09-J18 Influenza and pneumonia
0.804 0.196 0.000
N43.3 Hydrocele, unspecified
0.803 0.197 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.802 0.198 0.000
A30-A49 Other bacterial diseases
0.801 0.199 0.000
H11 Other disorders of conjunctiva
0.799 0.201 0.000
C15-C26 Malignant neoplasms of digestive organs
0.799 0.201 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.793 0.207 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.793 0.207 0.000
C79 Secondary malignant neoplasm of other sites
0.790 0.210 0.000
Z42.2 Follow-up care involving plastic surgery of other parts of trunk
0.789 0.210 0.000
D00-D09 In situ neoplasms
0.787 0.213 0.000
N60 Benign mammary dysplasia
0.787 0.213 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.786 0.214 0.000
J98 Other respiratory disorders
0.785 0.215 0.000
Z53.0 Procedure not carried out because of contraindication
0.784 0.216 0.000
Z45 Adjustment and management of implanted device
0.784 0.216 0.000
Z00.0 General medical examination
0.783 0.217 0.000
F30-F39 Mood [affective] disorders
0.783 0.217 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.780 0.220 0.000
C80 Malignant neoplasm without specification of site
0.780 0.220 0.000
N62 Hypertrophy of breast
0.776 0.224 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.775 0.225 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.774 0.226 0.000
S61.8 Open wound of other parts of wrist and hand
0.773 0.227 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.773 0.227 0.000
S20-S29 Injuries to the thorax
0.773 0.227 0.000
N64 Other disorders of breast
0.772 0.228 0.000
C50.0 Nipple and areola
0.772 0.228 0.000
J39 Other diseases of upper respiratory tract
0.772 0.228 0.000
H54 Blindness and low vision
0.772 0.228 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.771 0.229 0.000
Z52 Donors of organs and tissues
0.769 0.231 0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.768 0.232 0.000
Z00.5 Examination of potential donor of organ and tissue
0.768 0.232 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.768 0.232 0.000
T66-T78 Other and unspecified effects of external causes
0.767 0.233 0.000
N17 Acute renal failure
0.766 0.234 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.766 0.234 0.000
H50.1 Divergent concomitant strabismus
0.765 0.235 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.764 0.236 0.000
Z51.3 Blood transfusion without reported diagnosis
0.764 0.236 0.000
N18 Chronic renal failure
0.764 0.236 0.000
J33.8 Other polyp of sinus
0.763 0.237 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.761 0.239 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.760 0.240 0.000
E28 Ovarian dysfunction
0.757 0.243 0.000
H60-H62 Diseases of external ear
0.757 0.243 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.757 0.243 0.000
S01.2 Open wound of nose
0.756 0.244 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.754 0.245 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.753 0.247 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.752 0.248 0.000
E78.2 Mixed hyperlipidaemia
0.749 0.251 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.749 0.251 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.749 0.251 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.748 0.251 0.000
T86 Failure and rejection of transplanted organs and tissues
0.748 0.252 0.000
B99-B99 Other infectious diseases
0.745 0.255 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.745 0.255 0.000
B35-B49 Mycoses
0.743 0.257 0.000
J32.8 Other chronic sinusitis
0.743 0.257 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.742 0.258 0.000
H10 Conjunctivitis
0.738 0.261 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.738 0.262 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.737 0.263 0.000
S05 Injury of eye and orbit
0.737 0.263 0.000
J00-J06 Acute upper respiratory infections
0.737 0.263 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.737 0.263 0.000
H35.0 Background retinopathy and retinal vascular changes
0.736 0.263 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.736 0.264 0.000
N00-N08 Glomerular diseases
0.736 0.264 0.000
H34 Retinal vascular occlusions
0.735 0.264 0.000
Z40 Prophylactic surgery
0.735 0.265 0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.733 0.267 0.000
S90-S99 Injuries to the ankle and foot
0.731 0.269 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.731 0.269 0.000
S70-S79 Injuries to the hip and thigh
0.731 0.269 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.730 0.270 0.000
Z12 Special screening examination for neoplasms
0.730 0.270 0.000
S67 Crushing injury of wrist and hand
0.729 0.271 0.000
H50.9 Strabismus, unspecified
0.728 0.272 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.728 0.272 0.000
N48.6 Balanitis xerotica obliterans
0.727 0.273 0.000
J36 Peritonsillar abscess
0.727 0.273 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.726 0.274 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.725 0.275 0.000
Z51.1 Chemotherapy session for neoplasm
0.722 0.278 0.000
S64 Injury of nerves at wrist and hand level
0.721 0.279 0.000
S40-S49 Injuries to the shoulder and upper arm
0.721 0.279 0.000
C56 Malignant neoplasm of ovary
0.721 0.279 0.000
Z42.0 Follow-up care involving plastic surgery of head and neck
0.721 0.279 0.000
C77.3 Axillary and upper limb lymph nodes
0.719 0.281 0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance
0.719 0.281 0.000
E40-E46 Malnutrition
0.718 0.281 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
Z54 Convalescence
0.717 0.283 0.000
Z44 Fitting and adjustment of external prosthetic device
0.717 0.283 0.000
H35.4 Peripheral retinal degeneration
0.716 0.284 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.716 0.284 0.000
C50.6 Axillary tail of breast
0.716 0.284 0.000
C69 Malignant neoplasm of eye and adnexa
0.716 0.284 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.714 0.286 0.000
N25-N29 Other disorders of kidney and ureter
0.714 0.286 0.000
H33 Retinal detachments and breaks
0.713 0.287 0.000
Z51.9 Medical care, unspecified
0.712 0.288 0.000
Z51.6 Desensitisation to allergens
0.712 0.288 0.000
S01.5 Open wound of lip and oral cavity
0.712 0.288 0.000
J37 Chronic laryngitis and laryngotracheitis
0.711 0.289 0.000
Z13.9 Special screening examination, unspecified
0.711 0.289 0.000
H65-H75 Diseases of middle ear and mastoid
0.711 0.289 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.710 0.290 0.000
C71.2 Temporal lobe
0.710 0.290 0.000
L60-L75 Disorders of skin appendages
0.709 0.291 0.000
N10-N16 Renal tubulo-interstitial diseases
0.709 0.291 0.000
N48.4 Impotence of organic origin
0.709 0.291 0.000
J40-J47 Chronic lower respiratory diseases
0.707 0.293 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.706 0.293 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.705 0.295 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.705 0.295 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.705 0.295 0.000
H36.0 Diabetic retinopathy
0.705 0.295 0.000
E83.5 Disorders of calcium metabolism
0.703 0.297 0.000
J30 Vasomotor and allergic rhinitis
0.703 0.297 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.702 0.298 0.000
H11.4 Other conjunctival vascular disorders and cysts
0.701 0.299 0.000
E00-E07 Disorders of thyroid gland
0.700 0.300 0.000
L40-L45 Papulosquamous disorders
0.700 0.300 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.700 0.300 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.700 0.300 0.000
T87 Complications peculiar to reattachment and amputation
0.700 0.300 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.700 0.300 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.699 0.300 0.000
J98.4 Other disorders of lung
0.699 0.301 0.000
C71.9 Brain, unspecified
0.698 0.302 0.000
J32.3 Chronic sphenoidal sinusitis
0.698 0.302 0.000
J32.2 Chronic ethmoidal sinusitis
0.698 0.302 0.000
J32.1 Chronic frontal sinusitis
0.698 0.302 0.000
F32 Depressive episode
0.696 0.304 0.000
N42 Other disorders of prostate
0.696 0.304 0.000
S01.3 Open wound of ear
0.695 0.305 0.000
E21.3 Hyperparathyroidism, unspecified
0.695 0.305 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.695 0.305 0.000
Z42.9 Follow-up care involving plastic surgery, unspecified
0.695 0.305 0.000
Z42.8 Follow-up care involving plastic surgery of other body part
0.695 0.305 0.000
Z42.4 Follow-up care involving plastic surgery of lower extremity
0.695 0.305 0.000
Z42.3 Follow-up care involving plastic surgery of upper extremity
0.695 0.305 0.000
N19 Unspecified renal failure
0.694 0.306 0.000
J60-J70 Lung diseases due to external agents
0.694 0.306 0.000
J32.0 Chronic maxillary sinusitis
0.693 0.306 0.000
Z13.5 Special screening examination for eye and ear disorders
0.693 0.307 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.693 0.307 0.000
H31 Other disorders of choroid
0.693 0.307 0.000
H30 Chorioretinal inflammation
0.693 0.307 0.000
Z10 Routine general health check-up of defined subpopulation
0.693 0.307 0.000
H61 Other disorders of external ear
0.692 0.308 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.691 0.309 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.691 0.309 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.690 0.310 0.000
S69 Other and unspecified injuries of wrist and hand
0.689 0.310 0.000
S65 Injury of blood vessels at wrist and hand level
0.689 0.310 0.000
S60 Superficial injury of wrist and hand
0.689 0.310 0.000
N18.9 Chronic renal failure, unspecified
0.690 0.310 0.000
S06 Intracranial injury
0.688 0.312 0.000
Z43 Attention to artificial openings
0.688 0.312 0.000
E21.0 Primary hyperparathyroidism
0.687 0.313 0.000
C78.0 Secondary malignant neoplasm of lung
0.687 0.313 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.687 0.313 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.687 0.313 0.000
B65-B83 Helminthiases
0.687 0.313 0.000
B50-B64 Protozoal diseases
0.687 0.313 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.687 0.313 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.687 0.313 0.000
A80-A89 Viral infections of the central nervous system
0.687 0.313 0.000
A75-A79 Rickettsioses
0.687 0.313 0.000
A70-A74 Other diseases caused by chlamydiae
0.687 0.313 0.000
A65-A69 Other spirochaetal diseases
0.687 0.313 0.000
A20-A28 Certain zoonotic bacterial diseases
0.687 0.313 0.000
A15-A19 Tuberculosis
0.687 0.313 0.000
L20-L30 Dermatitis and eczema
0.686 0.314 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.686 0.314 0.000
N41 Inflammatory diseases of prostate
0.686 0.314 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.685 0.315 0.000
M20-M25 Other joint disorders
0.685 0.315 0.000
E27 Other disorders of adrenal gland
0.683 0.317 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.681 0.319 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.681 0.319 0.000
H54.7 Unspecified visual loss
0.679 0.321 0.000
E22 Hyperfunction of pituitary gland
0.678 0.322 0.000
S08 Traumatic amputation of part of head
0.677 0.323 0.000
S07 Crushing injury of head
0.677 0.323 0.000
S04 Injury of cranial nerves
0.677 0.323 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.677 0.323 0.000
Z01.9 Special examination, unspecified
0.676 0.324 0.000
Z01.7 Laboratory examination
0.676 0.324 0.000
Z01.5 Diagnostic skin and sensitisation tests
0.676 0.324 0.000
Z01.4 Gynaecological examination (general)(routine)
0.676 0.324 0.000
Z01.3 Examination of blood pressure
0.676 0.324 0.000
Z01.2 Dental examination
0.676 0.324 0.000
Z01.1 Examination of ears and hearing
0.676 0.324 0.000
Z01.0 Examination of eyes and vision
0.676 0.324 0.000
E85 Amyloidosis
0.676 0.324 0.000
E84 Cystic fibrosis
0.676 0.324 0.000
E79 Disorders of purine and pyrimidine metabolism
0.676 0.324 0.000
E77 Disorders of glycoprotein metabolism
0.676 0.324 0.000
E76 Disorders of glycosaminoglycan metabolism
0.676 0.324 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.676 0.324 0.000
E74 Other disorders of carbohydrate metabolism
0.676 0.324 0.000
E73 Lactose intolerance
0.676 0.324 0.000
E72 Other disorders of amino-acid metabolism
0.676 0.324 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.676 0.324 0.000
E70 Disorders of aromatic amino-acid metabolism
0.676 0.324 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.676 0.324 0.000
Z47.9 Orthopaedic follow-up care, unspecified
0.675 0.325 0.000
Z13.6 Special screening examination for cardiovascular disorders
0.675 0.325 0.000
H55-H59 Other disorders of eye and adnexa
0.673 0.327 0.000
S01.1 Open wound of eyelid and periocular area
0.672 0.328 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.672 0.328 0.000
N17.9 Acute renal failure, unspecified
0.672 0.328 0.000
C77.5 Intrapelvic lymph nodes
0.671 0.328 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.672 0.328 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.671 0.329 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.670 0.330 0.000
E83.3 Disorders of phosphorus metabolism
0.669 0.331 0.000
N50 Other disorders of male genital organs
0.668 0.332 0.000
L60 Nail disorders
0.668 0.332 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.667 0.333 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.667 0.333 0.000
N46 Male infertility
0.667 0.333 0.000
N44 Torsion of testis
0.667 0.333 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.667 0.333 0.000
D50-D53 Nutritional anaemias
0.666 0.334 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.666 0.334 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.666 0.334 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.666 0.334 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.666 0.334 0.000
Z02 Examination and encounter for administrative purposes
0.665 0.335 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.665 0.335 0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.665 0.335 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.665 0.335 0.000
C77.4 Inguinal and lower limb lymph nodes
0.663 0.337 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.663 0.337 0.000
Z51.8 Other specified medical care
0.663 0.337 0.000
J38.6 Stenosis of larynx
0.661 0.339 0.000
J38.5 Laryngeal spasm
0.661 0.339 0.000
J38.2 Nodules of vocal cords
0.661 0.339 0.000
J38.0 Paralysis of vocal cords and larynx
0.661 0.339 0.000
E29 Testicular dysfunction
0.661 0.339 0.000
E88 Other metabolic disorders
0.660 0.340 0.000
S01.7 Multiple open wounds of head
0.660 0.340 0.000
S01.4 Open wound of cheek and temporomandibular area
0.660 0.340 0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
0.660 0.340 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.660 0.340 0.000
H35.9 Retinal disorder, unspecified
0.659 0.341 0.000
H35.7 Separation of retinal layers
0.659 0.341 0.000
H35.6 Retinal haemorrhage
0.659 0.341 0.000
H35.5 Hereditary retinal dystrophy
0.659 0.341 0.000
H35.2 Other proliferative retinopathy
0.659 0.341 0.000
H35.1 Retinopathy of prematurity
0.659 0.341 0.000
J38.4 Oedema of larynx
0.658 0.342 0.000
E67 Other hyperalimentation
0.658 0.342 0.000
E68 Sequelae of hyperalimentation
0.658 0.342 0.000
E65 Localised adiposity
0.658 0.342 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.657 0.343 0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.656 0.344 0.000
C70 Malignant neoplasm of meninges
0.656 0.344 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.656 0.344 0.000
E34 Other endocrine disorders
0.656 0.344 0.000
E32 Diseases of thymus
0.656 0.344 0.000
E31 Polyglandular dysfunction
0.656 0.344 0.000
E30 Disorders of puberty, not elsewhere classified
0.656 0.344 0.000
E26 Hyperaldosteronism
0.656 0.344 0.000
E25 Adrenogenital disorders
0.656 0.344 0.000
E24 Cushing's syndrome
0.656 0.344 0.000
E20 Hypoparathyroidism
0.656 0.344 0.000
T39.1 4-Aminophenol derivatives
0.656 0.344 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.656 0.344 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.656 0.344 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.656 0.344 0.000
B15-B19 Viral hepatitis
0.655 0.344 0.000
C71.1 Frontal lobe
0.655 0.344 0.000
J35 Chronic diseases of tonsils and adenoids
0.655 0.345 0.000
E50-E64 Other nutritional deficiencies
0.655 0.345 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.655 0.345 0.000
A41 Other septicaemia
0.655 0.345 0.000
Z47.8 Other specified orthopaedic follow-up care
0.654 0.346 0.000
N60.3 Fibrosclerosis of breast
0.653 0.347 0.000
N60.0 Solitary cyst of breast
0.651 0.349 0.000
F32.9 Depressive episode, unspecified
0.651 0.349 0.000
C21 Malignant neoplasm of anus and anal canal
0.650 0.350 0.000
S82 Fracture of lower leg, including ankle
0.650 0.350 0.000
C18 Malignant neoplasm of colon
0.650 0.350 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.650 0.350 0.000
A46 Erysipelas
0.650 0.350 0.000
H51 Other disorders of binocular movement
0.649 0.351 0.000
H49 Paralytic strabismus
0.649 0.351 0.000
N48.1 Balanoposthitis
0.649 0.351 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.649 0.351 0.000
S01.8 Open wound of other parts of head
0.649 0.351 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.648 0.352 0.000
H13 Disorders of conjunctiva in diseases classified elsewhere
0.647 0.353 0.000
E78.8 Other disorders of lipoprotein metabolism
0.647 0.353 0.000
E78.6 Lipoprotein deficiency
0.647 0.353 0.000
E78.4 Other hyperlipidaemia
0.647 0.353 0.000
E78.3 Hyperchylomicronaemia
0.647 0.353 0.000
E78.1 Pure hyperglyceridaemia
0.647 0.353 0.000
N64.8 Other specified disorders of breast
0.646 0.354 0.000
H61.2 Impacted cerumen
0.646 0.354 0.000
N99-N99 Other disorders of the genitourinary system
0.646 0.354 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.645 0.355 0.000
J90-J94 Other diseases of pleura
0.644 0.356 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.644 0.356 0.000
E28.2 Polycystic ovarian syndrome
0.644 0.356 0.000
Z49.1 Extracorporeal dialysis
0.643 0.357 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.643 0.357 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.643 0.357 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.643 0.357 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.643 0.357 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.643 0.357 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.643 0.357 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.643 0.357 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.643 0.357 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.643 0.357 0.000
T36 Poisoning by systemic antibiotics
0.643 0.357 0.000
M23 Internal derangement of knee
0.642 0.358 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.642 0.358 0.000
T81.9 Unspecified complication of procedure
0.640 0.360 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.640 0.360 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.640 0.360 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.640 0.360 0.000
S01.9 Open wound of head, part unspecified
0.640 0.360 0.000
S02 Fracture of skull and facial bones
0.639 0.360 0.000
F99-F99 Unspecified mental disorder
0.639 0.361 0.000
Z00.8 Other general examinations
0.639 0.361 0.000
Z00.6 Examination for normal comparison and control in clinical research programme
0.639 0.361 0.000
Z00.4 General psychiatric examination, not elsewhere classified
0.639 0.361 0.000
Z00.3 Examination for adolescent development state
0.639 0.361 0.000
Z00.2 Examination for period of rapid growth in childhood
0.639 0.361 0.000
Z00.1 Routine child health examination
0.639 0.361 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.639 0.361 0.000
F31 Bipolar affective disorder
0.639 0.361 0.000
Z53.8 Procedure not carried out for other reasons
0.639 0.361 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.638 0.362 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.638 0.362 0.000
S61.7 Multiple open wounds of wrist and hand
0.638 0.362 0.000
S80 Superficial injury of lower leg
0.637 0.363 0.000
H72 Perforation of tympanic membrane
0.637 0.363 0.000
D60-D64 Aplastic and other anaemias
0.637 0.363 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.636 0.363 0.000
Z71.8 Other specified counselling
0.636 0.364 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.636 0.364 0.000
B07 Viral warts
0.635 0.365 0.000
Chapter XX External causes of morbidity and mortality
0.634 0.366 0.000
L50-L54 Urticaria and erythema
0.634 0.366 0.000
C50.3 Lower-inner quadrant of breast
0.633 0.367 0.000
S50-S59 Injuries to the elbow and forearm
0.633 0.367 0.000
H54.0 Blindness, both eyes
0.633 0.367 0.000
C34 Malignant neoplasm of bronchus and lung
0.632 0.368 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.632 0.368 0.000
S68 Traumatic amputation of wrist and hand
0.630 0.370 0.000
H11.3 Conjunctival haemorrhage
0.628 0.372 0.000
J34 Other disorders of nose and nasal sinuses
0.628 0.372 0.000
C77.1 Intrathoracic lymph nodes
0.628 0.372 0.000
D48.6 Breast
0.627 0.373 0.000
J38.3 Other diseases of vocal cords
0.627 0.373 0.000
F60-F69 Disorders of adult personality and behaviour
0.626 0.374 0.000
E23 Hypofunction and other disorders of pituitary gland
0.625 0.375 0.000
H50.0 Convergent concomitant strabismus
0.625 0.375 0.000
B02 Zoster [herpes zoster]
0.625 0.375 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.624 0.375 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.624 0.375 0.000
H53 Visual disturbances
0.624 0.376 0.000
S62 Fracture at wrist and hand level
0.624 0.376 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.624 0.376 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.623 0.377 0.000
J96 Respiratory failure, not elsewhere classified
0.623 0.377 0.000
E89.0 Postprocedural hypothyroidism
0.623 0.377 0.000
T51 Toxic effect of alcohol
0.623 0.377 0.000
Z48 Other surgical follow-up care
0.623 0.377 0.000
F80-F89 Disorders of psychological development
0.622 0.378 0.000
Z49.0 Preparatory care for dialysis
0.622 0.378 0.000
D46 Myelodysplastic syndromes
0.622 0.378 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.621 0.379 0.000
E66.1 Drug-induced obesity
0.621 0.379 0.000
E66.0 Obesity due to excess calories
0.621 0.379 0.000
H10.9 Conjunctivitis, unspecified
0.621 0.379 0.000
S00 Superficial injury of head
0.621 0.379 0.000
E66.9 Obesity, unspecified
0.620 0.380 0.000
T39.0 Salicylates
0.620 0.380 0.000
D05 Carcinoma in situ of breast
0.619 0.381 0.000
D45 Polycythaemia vera
0.619 0.381 0.000
H02 Other disorders of eyelid
0.619 0.381 0.000
C53 Malignant neoplasm of cervix uteri
0.618 0.381 0.000
Z46 Fitting and adjustment of other devices
0.617 0.383 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.617 0.383 0.000
Z13.8 Special screening examination for other specified diseases and disorders
0.617 0.383 0.000
Z13.7 Special screening examination for congenital malformations, deformations and chromosomal abnormalities
0.617 0.383 0.000
Z13.4 Special screening examination for certain developmental disorders in childhood
0.617 0.383 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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