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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs10999556
log Bayes Factor = 11.1577
Chromosome 10   position 72,571,360  (GRCh37) Explore rs10999556 on Ensembl!
Variant rs10999556 is part of Cluster X0102

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
M50-M54 Other dorsopathies
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
0.999 0.001 0.000
# Top node
0.999 0.001 0.000
Chapter IX Diseases of the circulatory system
0.998 0.002 0.000
F30-F39 Mood [affective] disorders
0.996 0.004 0.000
I44 Atrioventricular and left bundle-branch block
0.995 0.005 0.000
M54 Dorsalgia
0.995 0.005 0.000
F32 Depressive episode
0.994 0.006 0.000
M20-M25 Other joint disorders
0.993 0.007 0.000
I50 Heart failure
0.992 0.008 0.000
F32.9 Depressive episode, unspecified
0.990 0.010 0.000
M15-M19 Arthrosis
0.987 0.013 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.985 0.015 0.000
I45 Other conduction disorders
0.984 0.016 0.000
M80-M85 Disorders of bone density and structure
0.984 0.016 0.000
I44.0 Atrioventricular block, first degree
0.983 0.017 0.000
M19 Other arthrosis
0.980 0.020 0.000
M19.9 Arthrosis, unspecified
0.976 0.024 0.000
I42 Cardiomyopathy
0.976 0.024 0.000
M23 Internal derangement of knee
0.972 0.028 0.000
M81 Osteoporosis without pathological fracture
0.972 0.028 0.000
I50.1 Left ventricular failure
0.970 0.030 0.000
M50 Cervical disk disorders
0.970 0.030 0.000
M54.9 Dorsalgia, unspecified
0.968 0.032 0.000
M19.94 Arthrosis, unspecified (Hand)
0.967 0.033 0.000
I45.1 Other and unspecified right bundle-branch block
0.965 0.035 0.000
M51 Other intervertebral disk disorders
0.964 0.036 0.000
M81.9 Osteoporosis, unspecified
0.961 0.039 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.958 0.042 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.950 0.050 0.000
I50.0 Congestive heart failure
0.942 0.058 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.940 0.060 0.000
M23.3 Other meniscus derangements
0.940 0.060 0.000
M18 Arthrosis of first carpometacarpal joint
0.939 0.061 0.000
Chapter XX External causes of morbidity and mortality
0.935 0.065 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.935 0.065 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.922 0.078 0.000
I44.7 Left bundle-branch block, unspecified
0.922 0.078 0.000
I31 Other diseases of pericardium
0.921 0.079 0.000
F20 Schizophrenia
0.912 0.088 0.000
M31 Other necrotising vasculopathies
0.905 0.095 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.900 0.100 0.000
M24 Other specific joint derangements
0.899 0.101 0.000
I34 Nonrheumatic mitral valve disorders
0.898 0.102 0.000
F41 Other anxiety disorders
0.896 0.104 0.000
I42.0 Dilated cardiomyopathy
0.893 0.107 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.890 0.110 0.000
M22 Disorders of patella
0.890 0.110 0.000
M45-M49 Spondylopathies
0.889 0.111 0.000
M51.8 Other specified intervertebral disk disorders
0.888 0.112 0.000
M40-M43 Deforming dorsopathies
0.881 0.119 0.000
Chapter I Certain infectious and parasitic diseases
0.878 0.122 0.000
F32.1 Moderate depressive episode
0.873 0.127 0.000
M50.3 Other cervical disk degeneration
0.872 0.128 0.000
Chapter VI Diseases of the nervous system
0.866 0.134 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.862 0.138 0.000
O80-O84 Delivery
0.862 0.138 0.000
M54.4 Lumbago with sciatica
0.857 0.143 0.000
M50.1 Cervical disk disorder with radiculopathy
0.853 0.147 0.000
M51.9 Intervertebral disk disorder, unspecified
0.851 0.149 0.000
F41.9 Anxiety disorder, unspecified
0.851 0.149 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.849 0.151 0.000
I20-I25 Ischaemic heart diseases
0.848 0.152 0.000
M23.8 Other internal derangements of knee
0.848 0.152 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.844 0.156 0.000
I51 Complications and ill-defined descriptions of heart disease
0.841 0.159 0.000
O85-O92 Complications predominantly related to the puerperium
0.841 0.159 0.000
I42.6 Alcoholic cardiomyopathy
0.835 0.165 0.000
M65-M68 Disorders of synovium and tendon
0.834 0.166 0.000
I36 Nonrheumatic tricuspid valve disorders
0.833 0.167 0.000
M31.6 Other giant cell arteritis
0.833 0.167 0.000
M54.3 Sciatica
0.833 0.167 0.000
V80-V89 Other land transport accidents
0.830 0.170 0.000
F20.0 Paranoid schizophrenia
0.823 0.177 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.823 0.177 0.000
I05-I09 Chronic rheumatic heart diseases
0.819 0.181 0.000
M54.6 Pain in thoracic spine
0.819 0.181 0.000
F20.9 Schizophrenia, unspecified
0.818 0.182 0.000
B95-B98 Bacterial, viral and other infectious agents
0.818 0.182 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.810 0.190 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.808 0.192 0.000
O60-O75 Complications of labour and delivery
0.806 0.194 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.806 0.194 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.805 0.195 0.000
I31.3 Pericardial effusion (noninflammatory)
0.804 0.196 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.804 0.196 0.000
M81.96 Osteoporosis, unspecified (Lower leg)
0.803 0.197 0.000
I45.3 Trifascicular block
0.800 0.200 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.800 0.200 0.000
I30 Acute pericarditis
0.799 0.201 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.798 0.202 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.796 0.204 0.000
I31.9 Disease of pericardium, unspecified
0.795 0.205 0.000
I44.1 Atrioventricular block, second degree
0.795 0.205 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.791 0.209 0.000
M54.8 Other dorsalgia
0.790 0.210 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.788 0.212 0.000
I24 Other acute ischaemic heart diseases
0.786 0.214 0.000
I51.7 Cardiomegaly
0.786 0.214 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.786 0.214 0.000
Chapter XXII Codes for special purposes
0.784 0.216 0.000
I44.6 Other and unspecified fascicular block
0.781 0.219 0.000
O30 Multiple gestation
0.780 0.220 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.780 0.220 0.000
M51.2 Other specified intervertebral disk displacement
0.780 0.220 0.000
M54.39 Sciatica (Site unspecified)
0.779 0.221 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.779 0.221 0.000
Y52 Agents primarily affecting the cardiovascular system
0.779 0.221 0.000
F41.2 Mixed anxiety and depressive disorder
0.778 0.222 0.000
O82 Single delivery by Caesarean section
0.778 0.222 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.776 0.224 0.000
I42.2 Other hypertrophic cardiomyopathy
0.775 0.225 0.000
M23.0 Cystic meniscus
0.775 0.225 0.000
M50.0 Cervical disk disorder with myelopathy
0.774 0.226 0.000
G20-G26 Extrapyramidal and movement disorders
0.771 0.229 0.000
M50.2 Other cervical disk displacement
0.769 0.231 0.000
I46 Cardiac arrest
0.766 0.234 0.000
M45 Ankylosing spondylitis
0.764 0.236 0.000
I21 Acute myocardial infarction
0.764 0.236 0.000
O36 Maternal care for other known or suspected foetal problems
0.762 0.238 0.000
M60-M63 Disorders of muscles
0.759 0.240 0.000
M23.4 Loose body in knee
0.759 0.241 0.000
I45.5 Other specified heart block
0.759 0.241 0.000
M24.1 Other articular cartilage disorders
0.759 0.241 0.000
F23 Acute and transient psychotic disorders
0.757 0.242 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.757 0.243 0.000
O44 Placenta praevia
0.757 0.243 0.000
M19.1 Posttraumatic arthrosis of other joints
0.756 0.244 0.000
M21 Other acquired deformities of limbs
0.753 0.247 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.753 0.247 0.000
F60-F69 Disorders of adult personality and behaviour
0.751 0.249 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.751 0.249 0.000
F80-F89 Disorders of psychological development
0.751 0.249 0.000
M43 Other deforming dorsopathies
0.750 0.250 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.749 0.251 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.747 0.253 0.000
V40-V49 Car occupant injured in transport accident
0.747 0.253 0.000
F30 Manic episode
0.747 0.253 0.000
M82 Osteoporosis in diseases classified elsewhere
0.746 0.254 0.000
I24.8 Other forms of acute ischaemic heart disease
0.745 0.255 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.745 0.255 0.000
M24.2 Disorder of ligament
0.744 0.256 0.000
M84 Disorders of continuity of bone
0.744 0.256 0.000
F32.0 Mild depressive episode
0.742 0.257 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.741 0.259 0.000
F33 Recurrent depressive disorder
0.741 0.259 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.741 0.259 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.739 0.261 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.739 0.261 0.000
I42.9 Cardiomyopathy, unspecified
0.737 0.263 0.000
M81.4 Drug-induced osteoporosis
0.736 0.264 0.000
I33 Acute and subacute endocarditis
0.733 0.266 0.000
M22.4 Chondromalacia patellae
0.732 0.268 0.000
M05-M14 Inflammatory polyarthropathies
0.731 0.269 0.000
W50-W64 Exposure to animate mechanical forces
0.729 0.271 0.000
X60-X84 Intentional self-harm
0.729 0.271 0.000
W00-W19 Falls
0.728 0.271 0.000
F03 Unspecified dementia
0.728 0.272 0.000
I44.3 Other and unspecified atrioventricular block
0.726 0.274 0.000
M54.2 Cervicalgia
0.726 0.274 0.000
I34.0 Mitral (valve) insufficiency
0.725 0.275 0.000
O86 Other puerperal infections
0.724 0.276 0.000
M19.90 Arthrosis, unspecified (Multiple sites)
0.724 0.276 0.000
F29 Unspecified nonorganic psychosis
0.723 0.277 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.723 0.277 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.723 0.277 0.000
I45.8 Other specified conduction disorders
0.722 0.278 0.000
M22.8 Other disorders of patella
0.719 0.281 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
M41 Scoliosis
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
F70-F79 Mental retardation
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
M54.1 Radiculopathy
0.716 0.284 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.715 0.285 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.715 0.285 0.000
F38 Other mood [affective] disorders
0.714 0.286 0.000
F34 Persistent mood [affective] disorders
0.714 0.286 0.000
F39 Unspecified mood [affective] disorder
0.714 0.286 0.000
F25 Schizoaffective disorders
0.714 0.286 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.714 0.286 0.000
I44.5 Left posterior fascicular block
0.713 0.286 0.000
I44.4 Left anterior fascicular block
0.713 0.286 0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.713 0.287 0.000
M54.0 Panniculitis affecting regions of neck and back
0.713 0.287 0.000
I47 Paroxysmal tachycardia
0.713 0.287 0.000
F32.8 Other depressive episodes
0.712 0.288 0.000
V80 Animal-rider or occupant of animal-drawn vehicle injured in transport accident
0.712 0.288 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.712 0.288 0.000
M33 Dermatopolymyositis
0.712 0.288 0.000
M32 Systemic lupus erythematosus
0.712 0.288 0.000
M30 Polyarteritis nodosa and related conditions
0.712 0.288 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.712 0.288 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.712 0.288 0.000
F45 Somatoform disorders
0.710 0.290 0.000
M67 Other disorders of synovium and tendon
0.710 0.290 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.710 0.290 0.000
M70-M79 Other soft tissue disorders
0.710 0.290 0.000
X10-X19 Contact with heat and hot substances
0.710 0.290 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.708 0.292 0.000
M15 Polyarthrosis
0.708 0.292 0.000
V10-V19 Pedal cyclist injured in transport accident
0.708 0.292 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.706 0.294 0.000
I45.4 Nonspecific intraventricular block
0.706 0.294 0.000
I45.0 Right fascicular block
0.706 0.294 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.706 0.294 0.000
M83 Adult osteomalacia
0.706 0.294 0.000
M53 Other dorsopathies, not elsewhere classified
0.703 0.297 0.000
M19.8 Other specified arthrosis
0.703 0.297 0.000
M19.2 Other secondary arthrosis
0.703 0.297 0.000
I21.9 Acute myocardial infarction, unspecified
0.702 0.298 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.702 0.298 0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.700 0.299 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.700 0.300 0.000
M47 Spondylosis
0.700 0.300 0.000
I45.6 Preexcitation syndrome
0.700 0.300 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.700 0.300 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.700 0.300 0.000
M19.97 Arthrosis, unspecified (Ankle and foot)
0.700 0.300 0.000
I42.8 Other cardiomyopathies
0.700 0.300 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.700 0.300 0.000
I42.5 Other restrictive cardiomyopathy
0.700 0.300 0.000
I42.4 Endocardial fibroelastosis
0.700 0.300 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.700 0.300 0.000
F99-F99 Unspecified mental disorder
0.699 0.301 0.000
I45.2 Bifascicular block
0.699 0.301 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.698 0.302 0.000
G20 Parkinson's disease
0.698 0.302 0.000
F40 Phobic anxiety disorders
0.698 0.302 0.000
F41.1 Generalised anxiety disorder
0.697 0.303 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.697 0.303 0.000
M23.9 Internal derangement of knee, unspecified
0.697 0.303 0.000
M23.1 Discoid meniscus (congenital)
0.697 0.303 0.000
M81.8 Other osteoporosis
0.697 0.303 0.000
M81.6 Localised osteoporosis [Lequesne]
0.697 0.303 0.000
M81.5 Idiopathic osteoporosis
0.697 0.303 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.697 0.303 0.000
M81.2 Osteoporosis of disuse
0.697 0.303 0.000
M81.1 Postoophorectomy osteoporosis
0.697 0.303 0.000
M81.0 Postmenopausal osteoporosis
0.697 0.303 0.000
M50.9 Cervical disk disorder, unspecified
0.695 0.305 0.000
M50.8 Other cervical disk disorders
0.695 0.305 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.694 0.306 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.694 0.306 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.694 0.306 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.694 0.306 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.694 0.306 0.000
G30-G32 Other degenerative diseases of the nervous system
0.694 0.306 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.694 0.306 0.000
B35-B49 Mycoses
0.694 0.306 0.000
M54.64 Pain in thoracic spine (Thoracic region)
0.693 0.307 0.000
G90-G99 Other disorders of the nervous system
0.692 0.308 0.000
O62 Abnormalities of forces of labour
0.691 0.309 0.000
M51.3 Other specified intervertebral disk degeneration
0.691 0.309 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.691 0.309 0.000
M51.4 Schmorl's nodes
0.691 0.309 0.000
W20-W49 Exposure to inanimate mechanical forces
0.691 0.309 0.000
M22.2 Patellofemoral disorders
0.690 0.310 0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)
0.689 0.311 0.000
M81.94 Osteoporosis, unspecified (Hand)
0.689 0.311 0.000
M81.93 Osteoporosis, unspecified (Forearm)
0.689 0.311 0.000
M81.92 Osteoporosis, unspecified (Upper arm)
0.689 0.311 0.000
M81.91 Osteoporosis, unspecified (Shoulder region)
0.689 0.311 0.000
F28 Other nonorganic psychotic disorders
0.687 0.313 0.000
F24 Induced delusional disorder
0.687 0.313 0.000
F21 Schizotypal disorder
0.687 0.313 0.000
F43 Reaction to severe stress, and adjustment disorders
0.685 0.315 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.685 0.315 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.685 0.315 0.000
O41 Other disorders of amniotic fluid and membranes
0.683 0.316 0.000
O47 False labour
0.683 0.317 0.000
M80 Osteoporosis with pathological fracture
0.683 0.317 0.000
I05 Rheumatic mitral valve diseases
0.683 0.317 0.000
I21.4 Acute subendocardial myocardial infarction
0.681 0.319 0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified
0.680 0.320 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.680 0.320 0.000
O30.0 Twin pregnancy
0.679 0.321 0.000
I45.9 Conduction disorder, unspecified
0.677 0.323 0.000
A15-A19 Tuberculosis
0.676 0.324 0.000
M54.5 Low back pain
0.675 0.325 0.000
F48 Other neurotic disorders
0.674 0.326 0.000
F44 Dissociative [conversion] disorders
0.674 0.326 0.000
M23.37 Other meniscus derangements-Capsular lig
0.674 0.326 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.674 0.326 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.674 0.326 0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint
0.674 0.326 0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral
0.674 0.326 0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint
0.674 0.326 0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral
0.674 0.326 0.000
M22.3 Other derangements of patella
0.672 0.328 0.000
B99-B99 Other infectious diseases
0.672 0.328 0.000
M24.5 Contracture of joint
0.671 0.329 0.000
O82.1 Delivery by emergency Caesarean section
0.670 0.330 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.670 0.330 0.000
Y35-Y36 Legal intervention and operations of war
0.670 0.330 0.000
Y10-Y34 Event of undetermined intent
0.670 0.330 0.000
Y00-Y09 Assault
0.670 0.330 0.000
X85-X99 Assault
0.670 0.330 0.000
X50-X57 Overexertion, travel and privation
0.670 0.330 0.000
X30-X39 Exposure to forces of nature
0.670 0.330 0.000
X20-X29 Contact with venomous animals and plants
0.670 0.330 0.000
X00-X09 Exposure to smoke, fire and flames
0.670 0.330 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.670 0.330 0.000
W75-W84 Other accidental threats to breathing
0.670 0.330 0.000
W65-W74 Accidental drowning and submersion
0.670 0.330 0.000
V98-V99 Other and unspecified transport accidents
0.670 0.330 0.000
V95-V97 Air and space transport accidents
0.670 0.330 0.000
V90-V94 Water transport accidents
0.670 0.330 0.000
V70-V79 Bus occupant injured in transport accident
0.670 0.330 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.670 0.330 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.670 0.330 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.670 0.330 0.000
V01-V09 Pedestrian injured in transport accident
0.670 0.330 0.000
F02 Dementia in other diseases classified elsewhere
0.669 0.331 0.000
M35 Other systemic involvement of connective tissue
0.669 0.331 0.000
M85 Other disorders of bone density and structure
0.667 0.333 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.667 0.333 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.664 0.335 0.000
I35 Nonrheumatic aortic valve disorders
0.664 0.336 0.000
O45 Premature separation of placenta [abruptio placentae]
0.661 0.339 0.000
O33 Maternal care for known or suspected disproportion
0.661 0.339 0.000
O31 Complications specific to multiple gestation
0.661 0.339 0.000
M91-M94 Chondropathies
0.661 0.339 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.660 0.339 0.000
I31.8 Other specified diseases of pericardium
0.660 0.340 0.000
I31.2 Haemopericardium, not elsewhere classified
0.660 0.340 0.000
I31.1 Chronic constrictive pericarditis
0.660 0.340 0.000
I31.0 Chronic adhesive pericarditis
0.660 0.340 0.000
M48 Other spondylopathies
0.660 0.340 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.659 0.341 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.658 0.342 0.000
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.656 0.344 0.000
I30.9 Acute pericarditis, unspecified
0.656 0.344 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.655 0.345 0.000
O82.0 Delivery by elective Caesarean section
0.655 0.345 0.000
I27 Other pulmonary heart diseases
0.654 0.345 0.000
M46 Other inflammatory spondylopathies
0.654 0.346 0.000
F20.8 Other schizophrenia
0.654 0.346 0.000
F20.6 Simple schizophrenia
0.654 0.346 0.000
F20.5 Residual schizophrenia
0.654 0.346 0.000
F20.4 Postschizophrenic depression
0.654 0.346 0.000
F20.3 Undifferentiated schizophrenia
0.654 0.346 0.000
F20.2 Catatonic schizophrenia
0.654 0.346 0.000
F20.1 Hebephrenic schizophrenia
0.654 0.346 0.000
I51.0 Cardiac septal defect, acquired
0.654 0.346 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.653 0.347 0.000
O87 Venous complications in the puerperium
0.652 0.348 0.000
I38 Endocarditis, valve unspecified
0.652 0.348 0.000
M23.5 Chronic instability of knee
0.650 0.350 0.000
M43.1 Spondylolisthesis
0.650 0.350 0.000
M86-M90 Other osteopathies
0.650 0.350 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.649 0.351 0.000
M31.9 Necrotising vasculopathy, unspecified
0.649 0.351 0.000
M31.8 Other specified necrotising vasculopathies
0.649 0.351 0.000
M31.7 Microscopic polyangiitis
0.649 0.351 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.649 0.351 0.000
M31.2 Lethal midline granuloma
0.649 0.351 0.000
M31.1 Thrombotic microangiopathy
0.649 0.351 0.000
M31.0 Hypersensitivity angiitis
0.649 0.351 0.000
F22 Persistent delusional disorders
0.648 0.351 0.000
M47.2 Other spondylosis with radiculopathy
0.648 0.352 0.000
I47.2 Ventricular tachycardia
0.645 0.355 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.645 0.355 0.000
M24.9 Joint derangement, unspecified
0.644 0.356 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.644 0.356 0.000
M24.7 Protrusio acetabuli
0.644 0.356 0.000
M24.6 Ankylosis of joint
0.644 0.356 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.644 0.356 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.644 0.356 0.000
M54.89 Other dorsalgia (Site unspecified)
0.643 0.357 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.643 0.357 0.000
F41.8 Other specified anxiety disorders
0.642 0.357 0.000
F41.3 Other mixed anxiety disorders
0.642 0.357 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.641 0.359 0.000
O86.4 Pyrexia of unknown origin following delivery
0.641 0.359 0.000
I24.1 Dressler's syndrome
0.640 0.359 0.000
O40 Polyhydramnios
0.640 0.360 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.640 0.360 0.000
M21.0 Valgus deformity, not elsewhere classified
0.639 0.360 0.000
M22.1 Recurrent subluxation of patella
0.638 0.362 0.000
M22.9 Disorder of patella, unspecified
0.638 0.362 0.000
M22.0 Recurrent dislocation of patella
0.638 0.362 0.000
M49 Spondylopathies in diseases classified elsewhere
0.637 0.362 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.637 0.363 0.000
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)
0.634 0.366 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.634 0.366 0.000
O80 Single spontaneous delivery
0.634 0.366 0.000
M42 Spinal osteochondrosis
0.631 0.369 0.000
M40 Kyphosis and lordosis
0.631 0.369 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.631 0.369 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.629 0.370 0.000
B50-B64 Protozoal diseases
0.629 0.370 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.629 0.370 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.629 0.370 0.000
A75-A79 Rickettsioses
0.629 0.370 0.000
A70-A74 Other diseases caused by chlamydiae
0.629 0.370 0.000
A65-A69 Other spirochaetal diseases
0.629 0.370 0.000
A20-A28 Certain zoonotic bacterial diseases
0.629 0.370 0.000
V80.9 Rider or occupant injured in other and unspecified transport accidents
0.628 0.372 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.628 0.372 0.000
M54.37 Sciatica (Lumbosacral region)
0.627 0.373 0.000
O36.6 Maternal care for excessive foetal growth
0.627 0.373 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.626 0.374 0.000
O66 Other obstructed labour
0.624 0.376 0.000
O44.1 Placenta praevia with haemorrhage
0.624 0.376 0.000
F31 Bipolar affective disorder
0.623 0.377 0.000
O32.9 Maternal care for malpresentation of foetus, unspecified
0.621 0.379 0.000
B25-B34 Other viral diseases
0.621 0.379 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.621 0.379 0.000
O43 Placental disorders
0.620 0.380 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.620 0.380 0.000
O36.9 Maternal care for foetal problem, unspecified
0.620 0.380 0.000
M24.0 Loose body in joint
0.618 0.382 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.618 0.382 0.000
F09 Unspecified organic or symptomatic mental disorder
0.618 0.382 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.618 0.382 0.000
F00 Dementia in Alzheimer's disease
0.618 0.382 0.000
O84 Multiple delivery
0.618 0.382 0.000
O83 Other assisted single delivery
0.618 0.382 0.000
W17 Other fall from one level to another
0.618 0.382 0.000
M54.49 Lumbago with sciatica (Site unspecified)
0.617 0.383 0.000
M25 Other joint disorders, not elsewhere classified
0.617 0.383 0.000
O36.3 Maternal care for signs of foetal hypoxia
0.616 0.384 0.000
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)
0.614 0.385 0.000
M54.47 Lumbago with sciatica (Lumbosacral region)
0.614 0.385 0.000
M54.45 Lumbago with sciatica (Thoracolumbar region)
0.614 0.385 0.000
M54.44 Lumbago with sciatica-Thoracic
0.614 0.385 0.000
M54.43 Lumbago with sciatica-Cervicothoracic
0.614 0.385 0.000
M54.42 Lumbago with sciatica-Cervical
0.614 0.385 0.000
M54.41 Lumbago with sciatica-Occipit-atl-axl
0.614 0.385 0.000
M54.40 Lumbago with sciatica (Multiple sites in spine)
0.614 0.385 0.000
F23.9 Acute and transient psychotic disorder, unspecified
0.614 0.386 0.000
V48 Car occupant injured in noncollision transport accident
0.612 0.388 0.000
I08 Multiple valve diseases
0.611 0.389 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.611 0.389 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.610 0.390 0.000
I23 Certain current complications following acute myocardial infarction
0.608 0.392 0.000
G70-G73 Diseases of myoneural junction and muscle
0.608 0.392 0.000
M23.87 Other internal derangements of knee (Capsular ligament)
0.608 0.392 0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)
0.608 0.392 0.000
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)
0.608 0.392 0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.608 0.392 0.000
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.608 0.392 0.000
M23.80 Other internal derangements of knee (Multiple sites)
0.608 0.392 0.000
I50.9 Heart failure, unspecified
0.607 0.393 0.000
M23.49 Loose body in knee-Unspec lig/men
0.607 0.393 0.000
M47.1 Other spondylosis with myelopathy
0.607 0.393 0.000
M65 Synovitis and tenosynovitis
0.607 0.393 0.000
Y42.7 Androgens and anabolic congeners
0.607 0.393 0.000
O75.7 Vaginal delivery following previous Caesarean section
0.607 0.393 0.000
M67.8 Other specified disorders of synovium and tendon
0.607 0.393 0.000
B15-B19 Viral hepatitis
0.606 0.394 0.000
M24.23 Disorder of ligament (Forearm)
0.605 0.395 0.000
M34 Systemic sclerosis
0.604 0.395 0.000
W18 Other fall on same level
0.604 0.396 0.000
I51.6 Cardiovascular disease, unspecified
0.603 0.397 0.000
I51.5 Myocardial degeneration
0.603 0.397 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.603 0.397 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.603 0.397 0.000
O92 Other disorders of breast and lactation associated with childbirth
0.603 0.397 0.000
O91 Infections of breast associated with childbirth
0.603 0.397 0.000
O89 Complications of anaesthesia during the puerperium
0.603 0.397 0.000
O88 Obstetric embolism
0.603 0.397 0.000
O85 Puerperal sepsis
0.603 0.397 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.602 0.398 0.000
B65-B83 Helminthiases
0.600 0.400 0.000
M06 Other rheumatoid arthritis
0.600 0.400 0.000
A30-A49 Other bacterial diseases
0.600 0.400 0.000
M66 Spontaneous rupture of synovium and tendon
0.599 0.400 0.000
M41.9 Scoliosis, unspecified
0.599 0.401 0.000
A80-A89 Viral infections of the central nervous system
0.598 0.401 0.000
F01 Vascular dementia
0.598 0.401 0.000
F42 Obsessive-compulsive disorder
0.598 0.402 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.598 0.402 0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)
0.598 0.402 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.598 0.402 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.598 0.402 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.598 0.402 0.000
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.597 0.403 0.000
I36.8 Other nonrheumatic tricuspid valve disorders
0.597 0.403 0.000
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.597 0.403 0.000
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.597 0.403 0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)
0.597 0.403 0.000
M54.35 Sciatica (Thoracolumbar region)
0.597 0.403 0.000
M54.34 Sciatica-Thoracic
0.597 0.403 0.000
M54.33 Sciatica-Cervicothoracic
0.597 0.403 0.000
M54.32 Sciatica-Cervical
0.597 0.403 0.000
M54.31 Sciatica-Occipit-atl-axl
0.597 0.403 0.000
M54.30 Sciatica (Multiple sites in spine)
0.597 0.403 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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