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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs11012732
log Bayes Factor = 26.3769
Chromosome 10   position 21,830,104  (GRCh37) Explore rs11012732 on Ensembl!
Variant rs11012732 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I10 Essential (primary) hypertension
1.000 0.000 0.000
Z86 Personal history of certain other diseases
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
D32.0 Cerebral meninges
1.000 0.000 0.000
D32 Benign neoplasm of meninges
1.000 0.000 0.000
E66 Obesity
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
E65-E68 Obesity and other hyperalimentation
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Z86.0 Personal history of other neoplasms
1.000 0.000 0.000
Z90 Acquired absence of organs, not elsewhere classified
1.000 0.000 0.000
I10-I15 Hypertensive diseases
1.000 0.000 0.000
D10-D36 Benign neoplasms
1.000 0.000 0.000
Z86.7 Personal history of diseases of the circulatory system
0.999 0.001 0.000
M54.5 Low back pain
0.999 0.001 0.000
E20-E35 Disorders of other endocrine glands
0.998 0.002 0.000
E66.8 Other obesity
0.998 0.002 0.000
Chapter IX Diseases of the circulatory system
0.998 0.002 0.000
Z98 Other postsurgical states
0.997 0.003 0.000
M54.56 Low back pain (Lumbar region)
0.997 0.003 0.000
M54 Dorsalgia
0.996 0.004 0.000
E66.9 Obesity, unspecified
0.996 0.004 0.000
Z90.7 Acquired absence of genital organ(s)
0.995 0.005 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.995 0.005 0.000
D35.1 Parathyroid gland
0.994 0.006 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.994 0.006 0.000
M50-M54 Other dorsopathies
0.994 0.006 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.994 0.006 0.000
Chapter VII Diseases of the eye and adnexa
0.993 0.007 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.992 0.008 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.991 0.009 0.000
Z80 Family history of malignant neoplasm
0.990 0.010 0.000
H10-H13 Disorders of conjunctiva
0.990 0.010 0.000
Z90.3 Acquired absence of part of stomach
0.989 0.011 0.000
H11 Other disorders of conjunctiva
0.988 0.012 0.000
I60-I69 Cerebrovascular diseases
0.988 0.012 0.000
Z98.1 Arthrodesis status
0.987 0.013 0.000
Z90.2 Acquired absence of lung [part of]
0.983 0.017 0.000
Chapter V Mental and behavioural disorders
0.983 0.017 0.000
Z86.4 Personal history of psychoactive substance abuse
0.982 0.018 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.982 0.018 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.981 0.019 0.000
Z80.3 Family history of malignant neoplasm of breast
0.980 0.020 0.000
I67 Other cerebrovascular diseases
0.978 0.022 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.977 0.023 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.974 0.026 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.972 0.028 0.000
C51-C58 Malignant neoplasms of female genital organs
0.971 0.029 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.969 0.031 0.000
Z98.8 Other specified postsurgical states
0.966 0.034 0.000
M54.59 Low back pain (Site unspecified)
0.965 0.035 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.965 0.035 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.965 0.035 0.000
D32.9 Meninges, unspecified
0.962 0.038 0.000
I67.8 Other specified cerebrovascular diseases
0.959 0.041 0.000
H18 Other disorders of cornea
0.957 0.043 0.000
Z97 Presence of other devices
0.957 0.043 0.000
M54.57 Low back pain (Lumbosacral region)
0.956 0.044 0.000
E23 Hypofunction and other disorders of pituitary gland
0.955 0.045 0.000
I62 Other nontraumatic intracranial haemorrhage
0.952 0.048 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.951 0.049 0.000
F41 Other anxiety disorders
0.947 0.053 0.000
C56 Malignant neoplasm of ovary
0.944 0.056 0.000
I67.2 Cerebral atherosclerosis
0.941 0.059 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.941 0.059 0.000
D37.4 Colon
0.938 0.062 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.936 0.064 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.934 0.066 0.000
E50-E64 Other nutritional deficiencies
0.934 0.066 0.000
M60-M63 Disorders of muscles
0.932 0.068 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.930 0.070 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.930 0.070 0.000
D12.8 Rectum
0.928 0.072 0.000
E21.3 Hyperparathyroidism, unspecified
0.928 0.072 0.000
E29 Testicular dysfunction
0.927 0.073 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.926 0.074 0.000
H11.0 Pterygium
0.922 0.078 0.000
D37.1 Stomach
0.921 0.079 0.000
Chapter XXII Codes for special purposes
0.920 0.080 0.000
Z72 Problems related to lifestyle
0.918 0.082 0.000
Z75 Problems related to medical facilities and other health care
0.917 0.083 0.000
Z72.0 Tobacco use
0.914 0.086 0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
0.913 0.087 0.000
I12 Hypertensive renal disease
0.912 0.088 0.000
C54 Malignant neoplasm of corpus uteri
0.912 0.088 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.909 0.091 0.000
D00-D09 In situ neoplasms
0.908 0.092 0.000
E28 Ovarian dysfunction
0.906 0.094 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.904 0.096 0.000
D30 Benign neoplasm of urinary organs
0.904 0.096 0.000
M62 Other disorders of muscle
0.904 0.096 0.000
E61 Deficiency of other nutrient elements
0.903 0.097 0.000
Z97.4 Presence of external hearing-aid
0.901 0.099 0.000
H17 Corneal scars and opacities
0.901 0.099 0.000
M05-M14 Inflammatory polyarthropathies
0.896 0.104 0.000
Z75.1 Person awaiting admission to adequate facility elsewhere
0.894 0.106 0.000
D05 Carcinoma in situ of breast
0.890 0.110 0.000
H11.4 Other conjunctival vascular disorders and cysts
0.889 0.111 0.000
I15 Secondary hypertension
0.888 0.112 0.000
E61.1 Iron deficiency
0.888 0.112 0.000
Chapter VI Diseases of the nervous system
0.886 0.114 0.000
E23.0 Hypopituitarism
0.885 0.115 0.000
C43 Malignant melanoma of skin
0.885 0.115 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.884 0.116 0.000
F40 Phobic anxiety disorders
0.884 0.116 0.000
H11.9 Disorder of conjunctiva, unspecified
0.884 0.116 0.000
M13 Other arthritis
0.882 0.118 0.000
C43.7 Malignant melanoma of lower limb, including hip
0.881 0.119 0.000
H16 Keratitis
0.881 0.119 0.000
H11.8 Other specified disorders of conjunctiva
0.880 0.120 0.000
E23.7 Disorder of pituitary gland, unspecified
0.880 0.120 0.000
M62.8 Other specified disorders of muscle
0.876 0.124 0.000
E29.1 Testicular hypofunction
0.874 0.126 0.000
H21 Other disorders of iris and ciliary body
0.869 0.131 0.000
C50-C50 Malignant neoplasm of breast
0.869 0.131 0.000
M13.9 Arthritis, unspecified
0.866 0.134 0.000
M54.4 Lumbago with sciatica
0.865 0.135 0.000
F70-F79 Mental retardation
0.857 0.143 0.000
D31 Benign neoplasm of eye and adnexa
0.856 0.144 0.000
H11.1 Conjunctival degenerations and deposits
0.854 0.146 0.000
D32.1 Spinal meninges
0.853 0.147 0.000
Z88.2 Personal history of allergy to sulphonamides
0.851 0.149 0.000
D30.3 Bladder
0.850 0.150 0.000
D12.6 Colon, unspecified
0.850 0.150 0.000
M54.8 Other dorsalgia
0.850 0.150 0.000
D27 Benign neoplasm of ovary
0.849 0.151 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.847 0.153 0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.847 0.153 0.000
Z80.8 Family history of malignant neoplasm of other organs or systems
0.847 0.153 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.846 0.154 0.000
H17.9 Corneal scar and opacity, unspecified
0.846 0.154 0.000
M51 Other intervertebral disk disorders
0.846 0.154 0.000
G90-G99 Other disorders of the nervous system
0.844 0.156 0.000
Z97.5 Presence of (intra-uterine) contraceptive device
0.843 0.157 0.000
D26 Other benign neoplasms of uterus
0.843 0.157 0.000
I60 Subarachnoid haemorrhage
0.839 0.161 0.000
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs
0.839 0.161 0.000
C54.9 Corpus uteri, unspecified
0.838 0.162 0.000
H18.2 Other corneal oedema
0.838 0.162 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.837 0.163 0.000
I67.1 Cerebral aneurysm, nonruptured
0.837 0.163 0.000
Z57 Occupational exposure to risk-factors
0.836 0.164 0.000
F30-F39 Mood [affective] disorders
0.836 0.164 0.000
D29 Benign neoplasm of male genital organs
0.836 0.164 0.000
G40-G47 Episodic and paroxysmal disorders
0.834 0.166 0.000
Chapter X Diseases of the respiratory system
0.831 0.169 0.000
I12.9 Hypertensive renal disease without renal failure
0.831 0.169 0.000
F31 Bipolar affective disorder
0.830 0.170 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.827 0.173 0.000
H18.9 Disorder of cornea, unspecified
0.825 0.175 0.000
Z98.2 Presence of cerebrospinal fluid drainage device
0.823 0.177 0.000
M86-M90 Other osteopathies
0.823 0.177 0.000
J90-J94 Other diseases of pleura
0.821 0.179 0.000
M62.86 Other specified disorders of muscle (Lower leg)
0.821 0.179 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.820 0.180 0.000
E28.3 Primary ovarian failure
0.818 0.182 0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.815 0.185 0.000
Z73 Problems related to life-management difficulty
0.811 0.189 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.810 0.190 0.000
F41.9 Anxiety disorder, unspecified
0.810 0.190 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.810 0.190 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.810 0.190 0.000
C43.5 Malignant melanoma of trunk
0.807 0.193 0.000
M62.81 Other specified disorders of muscle (Shoulder region)
0.805 0.195 0.000
F40.0 Agoraphobia
0.805 0.195 0.000
D26.1 Corpus uteri
0.804 0.196 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.804 0.196 0.000
H18.1 Bullous keratopathy
0.802 0.198 0.000
J91 Pleural effusion in conditions classified elsewhere
0.801 0.199 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.801 0.199 0.000
H18.5 Hereditary corneal dystrophies
0.801 0.199 0.000
D44.7 Aortic body and other paraganglia
0.798 0.201 0.000
H11.2 Conjunctival scars
0.796 0.204 0.000
G43 Migraine
0.795 0.205 0.000
F44 Dissociative [conversion] disorders
0.794 0.206 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.794 0.206 0.000
C51 Malignant neoplasm of vulva
0.792 0.208 0.000
Z58 Problems related to physical environment
0.792 0.208 0.000
D37.3 Appendix
0.791 0.209 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.791 0.209 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.789 0.211 0.000
J92 Pleural plaque
0.789 0.211 0.000
F42 Obsessive-compulsive disorder
0.786 0.214 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.785 0.215 0.000
Z80.5 Family history of malignant neoplasm of urinary tract
0.783 0.217 0.000
E31 Polyglandular dysfunction
0.782 0.217 0.000
G91 Hydrocephalus
0.781 0.219 0.000
D29.1 Prostate
0.780 0.220 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.780 0.220 0.000
E65 Localised adiposity
0.779 0.221 0.000
G30-G32 Other degenerative diseases of the nervous system
0.778 0.222 0.000
H16.1 Other superficial keratitis without conjunctivitis
0.776 0.224 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.776 0.224 0.000
C50 Malignant neoplasm of breast
0.775 0.225 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.775 0.225 0.000
I13 Hypertensive heart and renal disease
0.774 0.226 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.774 0.226 0.000
M54.54 Low back pain-Thoracic
0.773 0.227 0.000
H13 Disorders of conjunctiva in diseases classified elsewhere
0.773 0.227 0.000
M54.6 Pain in thoracic spine
0.773 0.227 0.000
D44.4 Craniopharyngeal duct
0.771 0.229 0.000
Z60 Problems related to social environment
0.771 0.229 0.000
E21.2 Other hyperparathyroidism
0.770 0.230 0.000
E34 Other endocrine disorders
0.770 0.230 0.000
J60-J70 Lung diseases due to external agents
0.769 0.231 0.000
F79 Unspecified mental retardation
0.767 0.233 0.000
C54.1 Endometrium
0.766 0.234 0.000
M54.86 Other dorsalgia (Lumbar region)
0.765 0.235 0.000
F41.8 Other specified anxiety disorders
0.763 0.237 0.000
H18.6 Keratoconus
0.763 0.237 0.000
D44.3 Pituitary gland
0.763 0.237 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.762 0.237 0.000
H15 Disorders of sclera
0.761 0.239 0.000
M51.2 Other specified intervertebral disk displacement
0.761 0.239 0.000
M13.8 Other specified arthritis
0.760 0.240 0.000
Z94 Transplanted organ and tissue status
0.759 0.241 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.759 0.241 0.000
Z88.5 Personal history of allergy to narcotic agent
0.758 0.242 0.000
I15.8 Other secondary hypertension
0.758 0.242 0.000
M62.88 Other specified disorders of muscle (Other)
0.758 0.242 0.000
M89 Other disorders of bone
0.756 0.244 0.000
M13.94 Arthritis, unspecified (Hand)
0.756 0.244 0.000
C50.4 Upper-outer quadrant of breast
0.755 0.245 0.000
G47 Sleep disorders
0.754 0.246 0.000
D31.0 Conjunctiva
0.754 0.246 0.000
D33.2 Brain, unspecified
0.753 0.247 0.000
F40.8 Other phobic anxiety disorders
0.752 0.248 0.000
E63 Other nutritional deficiencies
0.752 0.248 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.749 0.251 0.000
Z97.0 Presence of artificial eye
0.747 0.253 0.000
C50.9 Breast, unspecified
0.747 0.253 0.000
D24 Benign neoplasm of breast
0.747 0.253 0.000
I11 Hypertensive heart disease
0.745 0.255 0.000
G97.8 Other postprocedural disorders of nervous system
0.745 0.255 0.000
M54.9 Dorsalgia, unspecified
0.744 0.256 0.000
H22.1 Iridocyclitis in other diseases classified elsewhere
0.744 0.256 0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.744 0.256 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.743 0.257 0.000
H21.1 Other vascular disorders of iris and ciliary body
0.743 0.257 0.000
H18.0 Corneal pigmentations and deposits
0.742 0.257 0.000
D44.1 Adrenal gland
0.742 0.258 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.741 0.259 0.000
Z97.2 Presence of dental prosthetic device (complete)(partial)
0.740 0.260 0.000
Z82.2 Family history of deafness and hearing loss
0.740 0.260 0.000
U51 Admission status on psychiatric patients
0.740 0.260 0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified
0.739 0.261 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.738 0.262 0.000
G91.1 Obstructive hydrocephalus
0.734 0.266 0.000
F60-F69 Disorders of adult personality and behaviour
0.731 0.269 0.000
Z99.2 Dependence on renal dialysis
0.731 0.269 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.728 0.272 0.000
D12.4 Descending colon
0.727 0.273 0.000
E51 Thiamine deficiency
0.726 0.274 0.000
Z57.5 Occupational exposure to toxic agents in other industries
0.726 0.274 0.000
M51.8 Other specified intervertebral disk disorders
0.726 0.274 0.000
M54.49 Lumbago with sciatica (Site unspecified)
0.725 0.275 0.000
D44.9 Endocrine gland, unspecified
0.725 0.275 0.000
D37.9 Digestive organ, unspecified
0.725 0.275 0.000
H55-H59 Other disorders of eye and adnexa
0.725 0.275 0.000
D12.5 Sigmoid colon
0.724 0.276 0.000
Z73.9 Problem related to life-management difficulty, unspecified
0.724 0.276 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.724 0.276 0.000
E66.0 Obesity due to excess calories
0.722 0.278 0.000
I15.1 Hypertension secondary to other renal disorders
0.722 0.278 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.722 0.278 0.000
Z81 Family history of mental and behavioural disorders
0.720 0.280 0.000
F51 Nonorganic sleep disorders
0.720 0.280 0.000
J92.9 Pleural plaque without asbestos
0.718 0.282 0.000
J92.0 Pleural plaque with presence of asbestos
0.718 0.282 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.717 0.282 0.000
E66.1 Drug-induced obesity
0.717 0.283 0.000
E67 Other hyperalimentation
0.717 0.283 0.000
E68 Sequelae of hyperalimentation
0.717 0.283 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.717 0.283 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.717 0.283 0.000
D19 Benign neoplasm of mesothelial tissue
0.717 0.283 0.000
M54.47 Lumbago with sciatica (Lumbosacral region)
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.716 0.283 0.000
M54.53 Low back pain-Cervicothoracic
0.716 0.284 0.000
M54.52 Low back pain-Cervical
0.716 0.284 0.000
M54.51 Low back pain-Occipit-atl-axl
0.716 0.284 0.000
E26 Hyperaldosteronism
0.716 0.284 0.000
M65-M68 Disorders of synovium and tendon
0.716 0.284 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.716 0.284 0.000
E32 Diseases of thymus
0.716 0.284 0.000
E30 Disorders of puberty, not elsewhere classified
0.716 0.284 0.000
E25 Adrenogenital disorders
0.716 0.284 0.000
D37.2 Small intestine
0.716 0.284 0.000
D38.1 Trachea, bronchus and lung
0.716 0.284 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.716 0.284 0.000
I12.0 Hypertensive renal disease with renal failure
0.716 0.284 0.000
G90 Disorders of autonomic nervous system
0.716 0.284 0.000
M89.0 Algoneurodystrophy
0.715 0.285 0.000
H21.9 Disorder of iris and ciliary body, unspecified
0.715 0.285 0.000
M54.0 Panniculitis affecting regions of neck and back
0.714 0.286 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.714 0.286 0.000
I00-I02 Acute rheumatic fever
0.714 0.286 0.000
D37.0 Lip, oral cavity and pharynx
0.713 0.286 0.000
D35.9 Endocrine gland, unspecified
0.713 0.287 0.000
D35.8 Pluriglandular involvement
0.713 0.287 0.000
D35.7 Other specified endocrine glands
0.713 0.287 0.000
D35.6 Aortic body and other paraganglia
0.713 0.287 0.000
D35.5 Carotid body
0.713 0.287 0.000
D35.4 Pineal gland
0.713 0.287 0.000
D35.3 Craniopharyngeal duct
0.713 0.287 0.000
E28.2 Polycystic ovarian syndrome
0.713 0.287 0.000
Z94.7 Corneal transplant status
0.713 0.287 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.711 0.289 0.000
Z93 Artificial opening status
0.709 0.291 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.708 0.292 0.000
H16.0 Corneal ulcer
0.708 0.292 0.000
Z97.3 Presence of spectacles and contact lenses
0.708 0.292 0.000
Z94.1 Heart transplant status
0.708 0.292 0.000
G43.1 Migraine with aura [classical migraine]
0.706 0.294 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.705 0.294 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.705 0.295 0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.704 0.296 0.000
M13.1 Monoarthritis, not elsewhere classified
0.704 0.296 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.703 0.297 0.000
F79.9 Unspecified mental retardation (Without mention of impairment of behaviour)
0.703 0.297 0.000
E21.0 Primary hyperparathyroidism
0.702 0.298 0.000
F43 Reaction to severe stress, and adjustment disorders
0.702 0.298 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.701 0.299 0.000
I67.5 Moyamoya disease
0.701 0.299 0.000
I67.4 Hypertensive encephalopathy
0.701 0.299 0.000
I67.3 Progressive vascular leukoencephalopathy
0.701 0.299 0.000
E21.4 Other specified disorders of parathyroid gland
0.700 0.300 0.000
Z75.4 Unavailability and inaccessibility of other helping agencies
0.700 0.300 0.000
H18.8 Other specified disorders of cornea
0.700 0.300 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.699 0.300 0.000
Z57.2 Occupational exposure to dust
0.699 0.301 0.000
H21.2 Degeneration of iris and ciliary body
0.698 0.302 0.000
M62.9 Disorder of muscle, unspecified
0.698 0.302 0.000
C58 Malignant neoplasm of placenta
0.696 0.304 0.000
G60 Hereditary and idiopathic neuropathy
0.694 0.306 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.693 0.307 0.000
D30.4 Urethra
0.693 0.307 0.000
M87 Osteonecrosis
0.691 0.309 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.690 0.310 0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.690 0.310 0.000
I61 Intracerebral haemorrhage
0.689 0.311 0.000
C64-C68 Malignant neoplasms of urinary tract
0.687 0.313 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.687 0.313 0.000
H18.7 Other corneal deformities
0.686 0.313 0.000
F41.3 Other mixed anxiety disorders
0.685 0.315 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.685 0.315 0.000
E23.1 Drug-induced hypopituitarism
0.685 0.315 0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.684 0.316 0.000
G47.9 Sleep disorder, unspecified
0.683 0.317 0.000
Z75.2 Other waiting period for investigation and treatment
0.682 0.318 0.000
H16.2 Keratoconjunctivitis
0.681 0.319 0.000
Z60.9 Problem related to social environment, unspecified
0.681 0.319 0.000
H46 Optic neuritis
0.681 0.319 0.000
I62.1 Nontraumatic extradural haemorrhage
0.680 0.320 0.000
G47.8 Other sleep disorders
0.678 0.322 0.000
M12 Other specific arthropathies
0.677 0.323 0.000
H16.3 Interstitial and deep keratitis
0.676 0.324 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.676 0.324 0.000
U51.0 Not Previously admitted to a psyciatric hospital
0.674 0.326 0.000
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues
0.673 0.327 0.000
E29.9 Testicular dysfunction, unspecified
0.673 0.327 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.672 0.328 0.000
J95-J99 Other diseases of the respiratory system
0.671 0.329 0.000
D44.8 Pluriglandular involvement
0.671 0.329 0.000
Z93.6 Other artificial openings of urinary tract status
0.671 0.329 0.000
D44.5 Pineal gland
0.670 0.330 0.000
D44.2 Parathyroid gland
0.670 0.330 0.000
D44.6 Carotid body
0.670 0.330 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.670 0.330 0.000
E50 Vitamin A deficiency
0.670 0.330 0.000
E60 Dietary zinc deficiency
0.670 0.330 0.000
E59 Dietary selenium deficiency
0.670 0.330 0.000
E52 Niacin deficiency [pellagra]
0.670 0.330 0.000
M14 Arthropathies in other diseases classified elsewhere
0.669 0.330 0.000
I15.0 Renovascular hypertension
0.669 0.331 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.669 0.331 0.000
Z57.3 Occupational exposure to other air contaminants
0.669 0.331 0.000
E56 Other vitamin deficiencies
0.668 0.331 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.668 0.332 0.000
M61 Calcification and ossification of muscle
0.668 0.332 0.000
M10 Gout
0.668 0.332 0.000
G56 Mononeuropathies of upper limb
0.668 0.332 0.000
D11 Benign neoplasm of major salivary glands
0.667 0.333 0.000
Z72.2 Drug use
0.666 0.334 0.000
Z58.7 Exposure to tobacco smoke
0.666 0.334 0.000
E29.8 Other testicular dysfunction
0.664 0.335 0.000
E29.0 Testicular hyperfunction
0.664 0.335 0.000
G31.8 Other specified degenerative diseases of nervous system
0.664 0.335 0.000
C51.0 Labium majus
0.663 0.337 0.000
E54 Ascorbic acid deficiency
0.663 0.337 0.000
F44.5 Dissociative convulsions
0.663 0.337 0.000
H21.4 Pupillary membranes
0.663 0.337 0.000
Z80.6 Family history of leukaemia
0.662 0.337 0.000
G56.2 Lesion of ulnar nerve
0.662 0.338 0.000
G43.8 Other migraine
0.662 0.338 0.000
H18.3 Changes in corneal membranes
0.661 0.339 0.000
Z61 Problems related to negative life events in childhood
0.661 0.339 0.000
J40-J47 Chronic lower respiratory diseases
0.660 0.340 0.000
H16.8 Other keratitis
0.660 0.340 0.000
H20 Iridocyclitis
0.659 0.341 0.000
Z72.6 Gambling and betting
0.658 0.342 0.000
Z72.5 High-risk sexual behaviour
0.658 0.342 0.000
Z72.3 Lack of physical exercise
0.658 0.342 0.000
Z75.9 Unspecified problem related to medical facilities and other health care
0.657 0.343 0.000
Z75.0 Medical services not available in home
0.657 0.343 0.000
M89.09 Algoneurodystrophy (Site unspecified)
0.657 0.343 0.000
F31.7 Bipolar affective disorder, currently in remission
0.657 0.343 0.000
U89 Agent resistant to other and unspecified antibiotics
0.657 0.343 0.000
G62 Other polyneuropathies
0.655 0.345 0.000
G95 Other diseases of spinal cord
0.655 0.345 0.000
D05.7 Other carcinoma in situ of breast
0.655 0.345 0.000
Z74 Problems related to care-provider dependency
0.655 0.345 0.000
C54.8 Overlapping lesion of corpus uteri
0.654 0.346 0.000
C54.3 Fundus uteri
0.654 0.346 0.000
C54.2 Myometrium
0.654 0.346 0.000
C54.0 Isthmus uteri
0.654 0.346 0.000
E20 Hypoparathyroidism
0.653 0.347 0.000
H10 Conjunctivitis
0.652 0.347 0.000
H55 Nystagmus and other irregular eye movements
0.652 0.348 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.652 0.348 0.000
Z62 Other problems related to upbringing
0.652 0.348 0.000
Z55 Problems related to education and literacy
0.652 0.348 0.000
H13.3 Ocular pemphigoid
0.650 0.350 0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.650 0.350 0.000
E28.9 Ovarian dysfunction, unspecified
0.650 0.350 0.000
E28.8 Other ovarian dysfunction
0.650 0.350 0.000
E28.1 Androgen excess
0.650 0.350 0.000
E28.0 Oestrogen excess
0.650 0.350 0.000
H21.0 Hyphaema
0.649 0.351 0.000
F34 Persistent mood [affective] disorders
0.649 0.351 0.000
D44.0 Thyroid gland
0.649 0.351 0.000
D04 Carcinoma in situ of skin
0.649 0.351 0.000
D30.9 Urinary organ, unspecified
0.648 0.352 0.000
D30.7 Other urinary organs
0.648 0.352 0.000
D30.2 Ureter
0.648 0.352 0.000
D30.1 Renal pelvis
0.648 0.352 0.000
M62.4 Contracture of muscle
0.648 0.352 0.000
M62.3 Immobility syndrome (paraplegic)
0.648 0.352 0.000
M62.2 Ischaemic infarction of muscle
0.648 0.352 0.000
J46 Status asthmaticus
0.648 0.352 0.000
C43.1 Malignant melanoma of eyelid, including canthus
0.647 0.353 0.000
E61.9 Deficiency of nutrient element, unspecified
0.647 0.353 0.000
E61.8 Deficiency of other specified nutrient elements
0.647 0.353 0.000
E61.7 Deficiency of multiple nutrient elements
0.647 0.353 0.000
E61.6 Vanadium deficiency
0.647 0.353 0.000
E61.5 Molybdenum deficiency
0.647 0.353 0.000
E61.4 Chromium deficiency
0.647 0.353 0.000
E61.3 Manganese deficiency
0.647 0.353 0.000
E61.0 Copper deficiency
0.647 0.353 0.000
F53 Mental and behavioural disorders associated with the puerperium, not elsewhere classified
0.647 0.353 0.000
J93 Pneumothorax
0.647 0.353 0.000
M54.3 Sciatica
0.647 0.353 0.000
M54.84 Other dorsalgia (Thoracic region)
0.647 0.353 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.647 0.353 0.000
H17.1 Other central corneal opacity
0.646 0.354 0.000
H17.0 Adherent leukoma
0.646 0.354 0.000
C65 Malignant neoplasm of renal pelvis
0.646 0.354 0.000
G63.2 Diabetic polyneuropathy
0.646 0.354 0.000
U88 Agent resistant to multiple antibiotics
0.645 0.355 0.000
F51.5 Nightmares
0.645 0.355 0.000
Z97.1 Presence of artificial limb (complete)(partial)
0.644 0.356 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.644 0.356 0.000
M66 Spontaneous rupture of synovium and tendon
0.644 0.356 0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)
0.643 0.357 0.000
M89.06 Algoneurodystrophy (Lower leg)
0.642 0.358 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.642 0.358 0.000
M08 Juvenile arthritis
0.642 0.358 0.000
G90.0 Idiopathic peripheral autonomic neuropathy
0.642 0.358 0.000
M00-M03 Infectious arthropathies
0.641 0.359 0.000
D33.0 Brain, supratentorial
0.640 0.360 0.000
D37.7 Other digestive organs
0.640 0.360 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.638 0.362 0.000
M54.63 Pain in thoracic spine (Cervicothoracic region)
0.637 0.363 0.000
I15.2 Hypertension secondary to endocrine disorders
0.637 0.363 0.000
E34.9 Endocrine disorder, unspecified
0.637 0.363 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.637 0.363 0.000
G41 Status epilepticus
0.637 0.363 0.000
M13.87 Other specified arthritis (Ankle and foot)
0.636 0.363 0.000
M62.89 Other specified disorders of muscle (Site unspecified)
0.636 0.364 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.636 0.364 0.000
C43.4 Malignant melanoma of scalp and neck
0.636 0.364 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.636 0.364 0.000
F42.0 Predominantly obsessional thoughts or ruminations
0.636 0.364 0.000
F31.8 Other bipolar affective disorders
0.635 0.365 0.000
F80-F89 Disorders of psychological development
0.635 0.365 0.000
C43.8 Overlapping malignant melanoma of skin
0.634 0.366 0.000
C43.0 Malignant melanoma of lip
0.634 0.366 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.634 0.366 0.000
F40.1 Social phobias
0.634 0.366 0.000
M62.6 Muscle strain
0.633 0.366 0.000
Z58.1 Exposure to air pollution
0.633 0.367 0.000
M87.2 Osteonecrosis due to previous trauma
0.633 0.367 0.000
Z82.1 Family history of blindness and visual loss
0.633 0.367 0.000
G54 Nerve root and plexus disorders
0.632 0.367 0.000
D33.4 Spinal cord
0.631 0.368 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.631 0.369 0.000
D04.3 Skin of other and unspecified parts of face
0.631 0.369 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.631 0.369 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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