TreeWAS – Variant ID: rs11121452

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Chapter XI Diseases of the digestive system	0.271	0.729	0.000
K55-K64 Other diseases of intestines	0.269	0.731	0.000
K62 Other diseases of anus and rectum	0.264	0.735	0.000
K90-K93 Other diseases of the digestive system	0.259	0.740	0.000
K62.5 Haemorrhage of anus and rectum	0.259	0.741	0.000
K92 Other diseases of digestive system	0.250	0.750	0.000
# Top node	0.250	0.750	0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.247	0.753	0.000
K70-K77 Diseases of liver	0.239	0.761	0.000
K63 Other diseases of intestine	0.236	0.764	0.000
K92.2 Gastro-intestinal haemorrhage, unspecified	0.234	0.766	0.000
Chapter V Mental and behavioural disorders	0.226	0.774	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.226	0.774	0.000
K80 Cholelithiasis	0.224	0.776	0.000
K92.0 Haematemesis	0.219	0.781	0.000
K60 Fissure and fistula of anal and rectal regions	0.218	0.782	0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.217	0.783	0.000
K76 Other diseases of liver	0.216	0.784	0.000
K61 Abscess of anal and rectal regions	0.214	0.786	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.214	0.786	0.000
K62.0 Anal polyp	0.212	0.787	0.000
K62.6 Ulcer of anus and rectum	0.211	0.789	0.000
K55 Vascular disorders of intestine	0.208	0.792	0.000
Chapter II Neoplasms	0.208	0.792	0.000
Chapter VI Diseases of the nervous system	0.206	0.794	0.000
K63.5 Polyp of colon	0.204	0.796	0.000
K65-K67 Diseases of peritoneum	0.201	0.799	0.000
K80.1 Calculus of gallbladder with other cholecystitis	0.200	0.800	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.197	0.802	0.000
Chapter I Certain infectious and parasitic diseases	0.197	0.803	0.000
K90 Intestinal malabsorption	0.196	0.804	0.000
K80.2 Calculus of gallbladder without cholecystitis	0.196	0.804	0.000
Chapter VIII Diseases of the ear and mastoid process	0.196	0.804	0.000
D10-D36 Benign neoplasms	0.195	0.805	0.000
K35-K38 Diseases of appendix	0.195	0.805	0.000
Chapter X Diseases of the respiratory system	0.194	0.806	0.000
K64 Haemorrhoids and perianal venous thrombosis	0.193	0.807	0.000
K62.9 Disease of anus and rectum, unspecified	0.190	0.810	0.000
K62.7 Radiation proctitis	0.190	0.810	0.000
K62.4 Stenosis of anus and rectum	0.190	0.810	0.000
K62.3 Rectal prolapse	0.190	0.810	0.000
K62.2 Anal prolapse	0.190	0.810	0.000
O60-O75 Complications of labour and delivery	0.189	0.811	0.000
K82 Other diseases of gallbladder	0.189	0.811	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.186	0.814	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.186	0.814	0.000
S60-S69 Injuries to the wrist and hand	0.186	0.814	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.184	0.816	0.000
K92.1 Melaena	0.184	0.816	0.000
K56 Paralytic ileus and intestinal obstruction without hernia	0.184	0.816	0.000
K62.1 Rectal polyp	0.184	0.816	0.000
K81 Cholecystitis	0.183	0.817	0.000
K76.9 Liver disease, unspecified	0.181	0.819	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.180	0.820	0.000
K92.9 Disease of digestive system, unspecified	0.180	0.820	0.000
K92.8 Other specified diseases of digestive system	0.180	0.820	0.000
Chapter XXII Codes for special purposes	0.179	0.820	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.179	0.820	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.179	0.820	0.000
K58 Irritable bowel syndrome	0.179	0.821	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.178	0.822	0.000
K63.9 Disease of intestine, unspecified	0.178	0.822	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.178	0.822	0.000
S00-S09 Injuries to the head	0.178	0.822	0.000
K76.8 Other specified diseases of liver	0.177	0.823	0.000
K62.8 Other specified diseases of anus and rectum	0.177	0.823	0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.177	0.823	0.000
K86 Other diseases of pancreas	0.177	0.823	0.000
K85 Acute pancreatitis	0.177	0.823	0.000
K83 Other diseases of biliary tract	0.177	0.823	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.177	0.823	0.000
K63.3 Ulcer of intestine	0.177	0.823	0.000
K60.2 Anal fissure, unspecified	0.176	0.824	0.000
F30-F39 Mood [affective] disorders	0.176	0.824	0.000
K61.0 Anal abscess	0.175	0.825	0.000
Chapter IX Diseases of the circulatory system	0.175	0.825	0.000
K14 Diseases of tongue	0.174	0.826	0.000
Chapter VII Diseases of the eye and adnexa	0.173	0.827	0.000
D22 Melanocytic naevi	0.171	0.828	0.000
K77 Liver disorders in diseases classified elsewhere	0.171	0.828	0.000
K75 Other inflammatory liver diseases	0.171	0.828	0.000
K74 Fibrosis and cirrhosis of liver	0.171	0.828	0.000
K73 Chronic hepatitis, not elsewhere classified	0.171	0.828	0.000
K72 Hepatic failure, not elsewhere classified	0.171	0.828	0.000
K71 Toxic liver disease	0.171	0.828	0.000
K70 Alcoholic liver disease	0.171	0.828	0.000
K63.8 Other specified diseases of intestine	0.171	0.829	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.171	0.829	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.170	0.830	0.000
K63.4 Enteroptosis	0.169	0.831	0.000
K63.2 Fistula of intestine	0.169	0.831	0.000
K63.1 Perforation of intestine (nontraumatic)	0.169	0.831	0.000
K63.0 Abscess of intestine	0.169	0.831	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.169	0.831	0.000
K08 Other disorders of teeth and supporting structures	0.169	0.831	0.000
O00-O08 Pregnancy with abortive outcome	0.168	0.832	0.000
B95-B98 Bacterial, viral and other infectious agents	0.167	0.833	0.000
J90-J94 Other diseases of pleura	0.166	0.833	0.000
K57 Diverticular disease of intestine	0.165	0.835	0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.165	0.835	0.000
K55.2 Angiodysplasia of colon	0.165	0.835	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.164	0.836	0.000
K60.3 Anal fistula	0.163	0.837	0.000
I30-I52 Other forms of heart disease	0.163	0.837	0.000
F99-F99 Unspecified mental disorder	0.162	0.838	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.162	0.838	0.000
F80-F89 Disorders of psychological development	0.162	0.838	0.000
F70-F79 Mental retardation	0.162	0.838	0.000
F60-F69 Disorders of adult personality and behaviour	0.162	0.838	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.162	0.838	0.000
O85-O92 Complications predominantly related to the puerperium	0.162	0.838	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.162	0.838	0.000
K80.3 Calculus of bile duct with cholangitis	0.161	0.839	0.000
K80.8 Other cholelithiasis	0.161	0.839	0.000
K80.4 Calculus of bile duct with cholecystitis	0.161	0.839	0.000
K02 Dental caries	0.160	0.840	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.160	0.840	0.000
G20-G26 Extrapyramidal and movement disorders	0.160	0.840	0.000
K50-K52 Noninfective enteritis and colitis	0.159	0.841	0.000
L60-L75 Disorders of skin appendages	0.158	0.842	0.000
O80-O84 Delivery	0.158	0.842	0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.158	0.842	0.000
G40-G47 Episodic and paroxysmal disorders	0.157	0.843	0.000
K04 Diseases of pulp and periapical tissues	0.157	0.843	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.156	0.843	0.001
Chapter XIV Diseases of the genitourinary system	0.156	0.844	0.000
K60.5 Anorectal fistula	0.156	0.844	0.000
K60.4 Rectal fistula	0.156	0.844	0.000
K60.1 Chronic anal fissure	0.156	0.844	0.000
K60.0 Acute anal fissure	0.156	0.844	0.000
K12 Stomatitis and related lesions	0.156	0.844	0.000
K11 Diseases of salivary glands	0.156	0.844	0.000
K10 Other diseases of jaws	0.156	0.844	0.000
K09 Cysts of oral region, not elsewhere classified	0.156	0.844	0.000
K07 Dentofacial anomalies [including malocclusion]	0.156	0.844	0.000
K06 Other disorders of gingiva and edentulous alveolar ridge	0.156	0.844	0.000
K05 Gingivitis and periodontal diseases	0.156	0.844	0.000
K03 Other diseases of hard tissues of teeth	0.156	0.844	0.000
K00 Disorders of tooth development and eruption	0.156	0.844	0.000
C15-C26 Malignant neoplasms of digestive organs	0.156	0.844	0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.156	0.844	0.000
D17 Benign lipomatous neoplasm	0.155	0.844	0.000
K76.7 Hepatorenal syndrome	0.155	0.845	0.000
K76.6 Portal hypertension	0.155	0.845	0.000
K76.5 Hepatic veno-occlusive disease	0.155	0.845	0.000
K76.4 Peliosis hepatis	0.155	0.845	0.000
K76.3 Infarction of liver	0.155	0.845	0.000
K76.2 Central haemorrhagic necrosis of liver	0.155	0.845	0.000
K76.1 Chronic passive congestion of liver	0.155	0.845	0.000
D23 Other benign neoplasms of skin	0.155	0.845	0.000
O68 Labour and delivery complicated by foetal stress [distress]	0.155	0.845	0.000
F03 Unspecified dementia	0.154	0.846	0.000
K61.4 Intrasphincteric abscess	0.154	0.846	0.000
K61.3 Ischiorectal abscess	0.154	0.846	0.000
K61.2 Anorectal abscess	0.154	0.846	0.000
K61.1 Rectal abscess	0.154	0.846	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.154	0.846	0.000
T79-T79 Certain early complications of trauma	0.154	0.846	0.000
T66-T78 Other and unspecified effects of external causes	0.154	0.846	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.154	0.846	0.000
T33-T35 Frostbite	0.154	0.846	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.154	0.846	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.154	0.846	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.154	0.846	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.154	0.846	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.154	0.846	0.000
T00-T07 Injuries involving multiple body regions	0.154	0.846	0.000
S90-S99 Injuries to the ankle and foot	0.154	0.846	0.000
S40-S49 Injuries to the shoulder and upper arm	0.154	0.846	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.154	0.846	0.000
S20-S29 Injuries to the thorax	0.154	0.846	0.000
S10-S19 Injuries to the neck	0.154	0.846	0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.153	0.847	0.000
D00-D09 In situ neoplasms	0.153	0.847	0.000
L20-L30 Dermatitis and eczema	0.153	0.847	0.000
K40-K46 Hernia	0.153	0.847	0.000
L00-L08 Infections of the skin and subcutaneous tissue	0.152	0.847	0.000
S70-S79 Injuries to the hip and thigh	0.152	0.848	0.000
S80-S89 Injuries to the knee and lower leg	0.152	0.848	0.000
H65-H75 Diseases of middle ear and mastoid	0.152	0.848	0.000
K13 Other diseases of lip and oral mucosa	0.151	0.849	0.000
K90.0 Coeliac disease	0.151	0.849	0.000
K66 Other disorders of peritoneum	0.151	0.849	0.000
K55.9 Vascular disorder of intestine, unspecified	0.149	0.850	0.000
K55.8 Other vascular disorders of intestine	0.149	0.850	0.000
K55.1 Chronic vascular disorders of intestine	0.149	0.850	0.000
K55.0 Acute vascular disorders of intestine	0.149	0.850	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.149	0.851	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.149	0.851	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.149	0.851	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.149	0.851	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.149	0.851	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.149	0.851	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.149	0.851	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.149	0.851	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.149	0.851	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.149	0.851	0.000
Chapter XX External causes of morbidity and mortality	0.149	0.851	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.149	0.851	0.000
J60-J70 Lung diseases due to external agents	0.148	0.852	0.000
C51-C58 Malignant neoplasms of female genital organs	0.148	0.852	0.000
B35-B49 Mycoses	0.148	0.852	0.000
K01 Embedded and impacted teeth	0.148	0.852	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.148	0.852	0.000
G70-G73 Diseases of myoneural junction and muscle	0.148	0.852	0.000
G30-G32 Other degenerative diseases of the nervous system	0.148	0.852	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.148	0.852	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.148	0.852	0.000
C50-C50 Malignant neoplasm of breast	0.148	0.852	0.000
K59 Other functional intestinal disorders	0.148	0.852	0.000
K82.8 Other specified diseases of gallbladder	0.148	0.852	0.000
G90-G99 Other disorders of the nervous system	0.147	0.852	0.000
S61 Open wound of wrist and hand	0.147	0.853	0.000
H55-H59 Other disorders of eye and adnexa	0.147	0.853	0.000
J90 Pleural effusion, not elsewhere classified	0.147	0.853	0.000
H90-H95 Other disorders of ear	0.146	0.853	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.146	0.854	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.146	0.854	0.000
S62 Fracture at wrist and hand level	0.145	0.854	0.000
D27 Benign neoplasm of ovary	0.145	0.855	0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.145	0.855	0.000
S01 Open wound of head	0.145	0.855	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.144	0.856	0.000
K67 Disorders of peritoneum in infectious diseases classified elsewhere	0.144	0.856	0.000
K65 Peritonitis	0.144	0.856	0.000
S50-S59 Injuries to the elbow and forearm	0.144	0.856	0.000
D22.5 Melanocytic naevi of trunk	0.144	0.856	0.000
O63 Long labour	0.144	0.856	0.000
K14.8 Other diseases of tongue	0.144	0.856	0.000
F20 Schizophrenia	0.143	0.857	0.000
C64-C68 Malignant neoplasms of urinary tract	0.142	0.858	0.000
N80-N98 Noninflammatory disorders of female genital tract	0.142	0.858	0.000
O16 Unspecified maternal hypertension	0.142	0.858	0.000
K56.5 Intestinal adhesions [bands] with obstruction	0.142	0.858	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.142	0.858	0.000
L50-L54 Urticaria and erythema	0.142	0.858	0.000
L10-L14 Bullous disorders	0.142	0.858	0.000
J95-J99 Other diseases of the respiratory system	0.142	0.858	0.000
K08.8 Other specified disorders of teeth and supporting structures	0.141	0.859	0.000
B99-B99 Other infectious diseases	0.141	0.859	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.141	0.859	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.141	0.859	0.000
B65-B83 Helminthiases	0.141	0.859	0.000
B50-B64 Protozoal diseases	0.141	0.859	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.141	0.859	0.000
B15-B19 Viral hepatitis	0.141	0.859	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.141	0.859	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.141	0.859	0.000
A80-A89 Viral infections of the central nervous system	0.141	0.859	0.000
A75-A79 Rickettsioses	0.141	0.859	0.000
A70-A74 Other diseases caused by chlamydiae	0.141	0.859	0.000
A65-A69 Other spirochaetal diseases	0.141	0.859	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.141	0.859	0.000
A20-A28 Certain zoonotic bacterial diseases	0.141	0.859	0.000
A15-A19 Tuberculosis	0.141	0.859	0.000
A30-A49 Other bacterial diseases	0.141	0.859	0.000
K90.9 Intestinal malabsorption, unspecified	0.141	0.859	0.000
K90.8 Other intestinal malabsorption	0.141	0.859	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.141	0.859	0.000
K90.3 Pancreatic steatorrhoea	0.141	0.859	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.141	0.859	0.000
K90.1 Tropical sprue	0.141	0.859	0.000
O70 Perineal laceration during delivery	0.141	0.859	0.000
H80-H83 Diseases of inner ear	0.140	0.859	0.000
H60-H62 Diseases of external ear	0.140	0.859	0.000
K35 Acute appendicitis	0.140	0.860	0.000
D36 Benign neoplasm of other and unspecified sites	0.140	0.860	0.000
D35 Benign neoplasm of other and unspecified endocrine glands	0.140	0.860	0.000
D33 Benign neoplasm of brain and other parts of central nervous system	0.140	0.860	0.000
D32 Benign neoplasm of meninges	0.140	0.860	0.000
D31 Benign neoplasm of eye and adnexa	0.140	0.860	0.000
D30 Benign neoplasm of urinary organs	0.140	0.860	0.000
D29 Benign neoplasm of male genital organs	0.140	0.860	0.000
D28 Benign neoplasm of other and unspecified female genital organs	0.140	0.860	0.000
D26 Other benign neoplasms of uterus	0.140	0.860	0.000
D21 Other benign neoplasms of connective and other soft tissue	0.140	0.860	0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.140	0.860	0.000
D19 Benign neoplasm of mesothelial tissue	0.140	0.860	0.000
D16 Benign neoplasm of bone and articular cartilage	0.140	0.860	0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.140	0.860	0.000
D14 Benign neoplasm of middle ear and respiratory system	0.140	0.860	0.000
D11 Benign neoplasm of major salivary glands	0.140	0.860	0.000
D10 Benign neoplasm of mouth and pharynx	0.140	0.860	0.000
D34 Benign neoplasm of thyroid gland	0.140	0.860	0.000
F32 Depressive episode	0.140	0.860	0.000
K38 Other diseases of appendix	0.140	0.860	0.000
K37 Unspecified appendicitis	0.140	0.860	0.000
K36 Other appendicitis	0.140	0.860	0.000
J30-J39 Other diseases of upper respiratory tract	0.139	0.861	0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.139	0.861	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.139	0.861	0.000
J00-J06 Acute upper respiratory infections	0.139	0.861	0.000
F40 Phobic anxiety disorders	0.139	0.861	0.000
K64.9 Haemorrhoids, unspecified	0.138	0.861	0.000
K64.8 Other specified haemorrhoids	0.138	0.861	0.000
K64.5 Perianal venous thrombosis	0.138	0.861	0.000
K64.4 Residual haemorrhoidal skin tags	0.138	0.861	0.000
K64.3 Fourth degree haemorrhoids	0.138	0.861	0.000
K64.2 Third degree haemorrhoids	0.138	0.861	0.000
K64.1 Second degree haemorrhoids	0.138	0.861	0.000
K64.0 First degree haemorrhoids	0.138	0.861	0.000
D24 Benign neoplasm of breast	0.138	0.861	0.000
F41 Other anxiety disorders	0.138	0.861	0.000
S00 Superficial injury of head	0.138	0.862	0.000
O72 Postpartum haemorrhage	0.138	0.862	0.000
Chapter XXI Factors influencing health status and contact with health services	0.138	0.862	0.000
M20-M25 Other joint disorders	0.138	0.862	0.000
K80.0 Calculus of gallbladder with acute cholecystitis	0.137	0.863	0.000
K81.1 Chronic cholecystitis	0.137	0.863	0.000
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess	0.137	0.863	0.000
H40-H42 Glaucoma	0.136	0.864	0.000
L40-L45 Papulosquamous disorders	0.136	0.864	0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.136	0.864	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.136	0.864	0.000
O74 Complications of anaesthesia during labour and delivery	0.136	0.864	0.000
O73 Retained placenta and membranes, without haemorrhage	0.136	0.864	0.000
O71 Other obstetric trauma	0.136	0.864	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.136	0.864	0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.136	0.864	0.000
O66 Other obstructed labour	0.136	0.864	0.000
O65 Obstructed labour due to maternal pelvic abnormality	0.136	0.864	0.000
O64 Obstructed labour due to malposition and malpresentation of foetus	0.136	0.864	0.000
O62 Abnormalities of forces of labour	0.136	0.864	0.000
O61 Failed induction of labour	0.136	0.864	0.000
O60 Preterm delivery	0.136	0.864	0.000
I44 Atrioventricular and left bundle-branch block	0.136	0.864	0.000
K82.9 Disease of gallbladder, unspecified	0.136	0.864	0.000
K82.4 Cholesterolosis of gallbladder	0.136	0.864	0.000
K82.3 Fistula of gallbladder	0.136	0.864	0.000
K82.2 Perforation of gallbladder	0.136	0.864	0.000
K82.1 Hydrops of gallbladder	0.136	0.864	0.000
K82.0 Obstruction of gallbladder	0.136	0.864	0.000
D22.7 Melanocytic naevi of lower limb, including hip	0.136	0.864	0.000
D60-D64 Aplastic and other anaemias	0.135	0.864	0.000
I35 Nonrheumatic aortic valve disorders	0.135	0.865	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.134	0.866	0.000
K91.9 Postprocedural disorder of digestive system, unspecified	0.134	0.866	0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.134	0.866	0.000
K91.5 Postcholecystectomy syndrome	0.134	0.866	0.000
K91.4 Colostomy and enterostomy malfunction	0.134	0.866	0.000
K91.3 Postoperative intestinal obstruction	0.134	0.866	0.000
K91.2 Postsurgical malabsorption, not elsewhere classified	0.134	0.866	0.000
K91.1 Postgastric surgery syndromes	0.134	0.866	0.000
K91.0 Vomiting following gastro-intestinal surgery	0.134	0.866	0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.134	0.866	0.000
K93.1 Megacolon in Chagas' disease	0.134	0.866	0.000
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.134	0.866	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.133	0.866	0.000
S69 Other and unspecified injuries of wrist and hand	0.133	0.867	0.000
S68 Traumatic amputation of wrist and hand	0.133	0.867	0.000
S67 Crushing injury of wrist and hand	0.133	0.867	0.000
S65 Injury of blood vessels at wrist and hand level	0.133	0.867	0.000
S64 Injury of nerves at wrist and hand level	0.133	0.867	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.133	0.867	0.000
S60 Superficial injury of wrist and hand	0.133	0.867	0.000
D18 Haemangioma and lymphangioma, any site	0.133	0.867	0.000
G50 Disorders of trigeminal nerve	0.133	0.867	0.000
I34 Nonrheumatic mitral valve disorders	0.133	0.867	0.000
D12.8 Rectum	0.132	0.868	0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.132	0.868	0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.132	0.868	0.000
F05 Delirium, not induced by alcohol and other psychoactive substances	0.132	0.868	0.000
F02 Dementia in other diseases classified elsewhere	0.132	0.868	0.000
F01 Vascular dementia	0.132	0.868	0.000
F00 Dementia in Alzheimer's disease	0.132	0.868	0.000
F09 Unspecified organic or symptomatic mental disorder	0.132	0.868	0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.132	0.868	0.000
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck	0.132	0.868	0.000
B25-B34 Other viral diseases	0.132	0.868	0.000
K56.7 Ileus, unspecified	0.132	0.868	0.000
K56.4 Other impaction of intestine	0.132	0.868	0.000
K56.3 Gallstone ileus	0.132	0.868	0.000
K56.2 Volvulus	0.132	0.868	0.000
K56.1 Intussusception	0.132	0.868	0.000
K56.0 Paralytic ileus	0.132	0.868	0.000
D12.3 Transverse colon	0.132	0.868	0.000
D22.3 Melanocytic naevi of other and unspecified parts of face	0.132	0.868	0.000
K81.9 Cholecystitis, unspecified	0.131	0.869	0.000
K81.8 Other cholecystitis	0.131	0.869	0.000
K81.0 Acute cholecystitis	0.131	0.869	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.131	0.869	0.000
O42 Premature rupture of membranes	0.130	0.869	0.000
J20-J22 Other acute lower respiratory infections	0.130	0.870	0.000
L72 Follicular cysts of skin and subcutaneous tissue	0.130	0.870	0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.130	0.870	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.129	0.870	0.000
J40-J47 Chronic lower respiratory diseases	0.129	0.871	0.000
L80-L99 Other disorders of the skin and subcutaneous tissue	0.129	0.871	0.000
F48 Other neurotic disorders	0.129	0.871	0.000
F45 Somatoform disorders	0.129	0.871	0.000
F44 Dissociative [conversion] disorders	0.129	0.871	0.000
F43 Reaction to severe stress, and adjustment disorders	0.129	0.871	0.000
F42 Obsessive-compulsive disorder	0.129	0.871	0.000
P90-P96 Other disorders originating in the perinatal period	0.129	0.871	0.000
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn	0.129	0.871	0.000
P75-P78 Digestive system disorders of fetus and newborn	0.129	0.871	0.000
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn	0.129	0.871	0.000
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn	0.129	0.871	0.000
P35-P39 Infections specific to the perinatal period	0.129	0.871	0.000
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period	0.129	0.871	0.000
P10-P15 Birth trauma	0.129	0.871	0.000
P05-P08 Disorders related to length of gestation and fetal growth	0.129	0.871	0.000
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery	0.129	0.871	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.129	0.871	0.000
Q80-Q89 Other congenital malformations	0.129	0.871	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.129	0.871	0.000
Q60-Q64 Congenital malformations of the urinary system	0.129	0.871	0.000
Q50-Q56 Congenital malformations of genital organs	0.129	0.871	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.129	0.871	0.000
Q35-Q37 Cleft lip and cleft palate	0.129	0.871	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.129	0.871	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.129	0.871	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.129	0.871	0.000
Q00-Q07 Congenital malformations of the nervous system	0.129	0.871	0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.129	0.871	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.129	0.871	0.000
H55 Nystagmus and other irregular eye movements	0.129	0.871	0.000
K58.0 Irritable bowel syndrome with diarrhoea	0.128	0.871	0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders	0.128	0.872	0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.128	0.872	0.000
O97 Death from sequelae of direct obstetric causes	0.128	0.872	0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.128	0.872	0.000
O95 Obstetric death of unspecified cause	0.128	0.872	0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.128	0.872	0.000
F25 Schizoaffective disorders	0.128	0.872	0.000
F23 Acute and transient psychotic disorders	0.128	0.872	0.000
F22 Persistent delusional disorders	0.128	0.872	0.000
F29 Unspecified nonorganic psychosis	0.128	0.872	0.000
F28 Other nonorganic psychotic disorders	0.128	0.872	0.000
F24 Induced delusional disorder	0.128	0.872	0.000
F21 Schizotypal disorder	0.128	0.872	0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.128	0.872	0.000
S08 Traumatic amputation of part of head	0.128	0.872	0.000
S07 Crushing injury of head	0.128	0.872	0.000
S06 Intracranial injury	0.128	0.872	0.000
S05 Injury of eye and orbit	0.128	0.872	0.000
S04 Injury of cranial nerves	0.128	0.872	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.128	0.872	0.000
S02 Fracture of skull and facial bones	0.128	0.872	0.000
K83.9 Disease of biliary tract, unspecified	0.127	0.873	0.000
K83.8 Other specified diseases of biliary tract	0.127	0.873	0.000
K83.5 Biliary cyst	0.127	0.873	0.000
K83.4 Spasm of sphincter of Oddi	0.127	0.873	0.000
K83.3 Fistula of bile duct	0.127	0.873	0.000
K83.2 Perforation of bile duct	0.127	0.873	0.000
K83.1 Obstruction of bile duct	0.127	0.873	0.000
K83.0 Cholangitis	0.127	0.873	0.000
K85.9 Acute pancreatitis, unspecified	0.127	0.873	0.000
K85.8 Other acute pancreatitis	0.127	0.873	0.000
K85.3 Drug-induced acute pancreatitis	0.127	0.873	0.000
K85.2 Alcohol-induced acute pancreatitis	0.127	0.873	0.000
K85.1 Biliary acute pancreatitis	0.127	0.873	0.000
K85.0 Idiopathic acute pancreatitis	0.127	0.873	0.000
K86.9 Disease of pancreas, unspecified	0.127	0.873	0.000
K86.8 Other specified diseases of pancreas	0.127	0.873	0.000
K86.3 Pseudocyst of pancreas	0.127	0.873	0.000
K86.2 Cyst of pancreas	0.127	0.873	0.000
K86.1 Other chronic pancreatitis	0.127	0.873	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.127	0.873	0.000
K87.1 Disorders of pancreas in diseases classified elsewhere	0.127	0.873	0.000
K87.0 Disorders of gallbladder and biliary tract in diseases classified elsewhere	0.127	0.873	0.000
O15 Eclampsia	0.127	0.873	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.127	0.873	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.127	0.873	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.127	0.873	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.127	0.873	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.127	0.873	0.000
N84 Polyp of female genital tract	0.127	0.873	0.000
S09 Other and unspecified injuries of head	0.127	0.873	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.127	0.873	0.000
A00-A09 Intestinal infectious diseases	0.126	0.873	0.000
G20 Parkinson's disease	0.126	0.873	0.000
I31 Other diseases of pericardium	0.126	0.874	0.000
F38 Other mood [affective] disorders	0.126	0.874	0.000
F34 Persistent mood [affective] disorders	0.126	0.874	0.000
F33 Recurrent depressive disorder	0.126	0.874	0.000
F31 Bipolar affective disorder	0.126	0.874	0.000
F30 Manic episode	0.126	0.874	0.000
F39 Unspecified mood [affective] disorder	0.126	0.874	0.000
I51 Complications and ill-defined descriptions of heart disease	0.125	0.875	0.000
I05-I09 Chronic rheumatic heart diseases	0.125	0.875	0.000
I00-I02 Acute rheumatic fever	0.125	0.875	0.000
K14.9 Disease of tongue, unspecified	0.125	0.875	0.000
K14.6 Glossodynia	0.125	0.875	0.000
K14.5 Plicated tongue	0.125	0.875	0.000
K14.4 Atrophy of tongue papillae	0.125	0.875	0.000
K14.3 Hypertrophy of tongue papillae	0.125	0.875	0.000
K14.2 Median rhomboid glossitis	0.125	0.875	0.000
K14.1 Geographic tongue	0.125	0.875	0.000
K14.0 Glossitis	0.125	0.875	0.000
G45 Transient cerebral ischaemic attacks and related syndromes	0.125	0.875	0.000
G57 Mononeuropathies of lower limb	0.125	0.875	0.000
O03 Spontaneous abortion	0.124	0.876	0.000
H53-H54 Visual disturbances and blindness	0.124	0.876	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.124	0.876	0.000
H43-H45 Disorders of vitreous body and globe	0.124	0.876	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.124	0.876	0.000
H10-H13 Disorders of conjunctiva	0.124	0.876	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.124	0.876	0.000
S61.9 Open wound of wrist and hand, part unspecified	0.124	0.876	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations