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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs111969502
log Bayes Factor = 5.3967
Chromosome 12   position 59,848,381  (GRCh37) Explore rs111969502 on Ensembl!
Variant rs111969502 is part of Cluster X0141

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
T36-T50 Poisoning by drugs, medicaments and biological substances
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
0.996 0.004 0.000
# Top node
0.995 0.005 0.000
F30-F39 Mood [affective] disorders
0.991 0.009 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.989 0.011 0.000
Chapter I Certain infectious and parasitic diseases
0.982 0.018 0.000
F31 Bipolar affective disorder
0.978 0.022 0.000
F33 Recurrent depressive disorder
0.963 0.037 0.000
Chapter XX External causes of morbidity and mortality
0.960 0.040 0.000
F31.9 Bipolar affective disorder, unspecified
0.959 0.041 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.957 0.043 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.951 0.049 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.946 0.054 0.000
A30-A49 Other bacterial diseases
0.940 0.060 0.000
Chapter X Diseases of the respiratory system
0.938 0.062 0.000
J44 Other chronic obstructive pulmonary disease
0.935 0.065 0.000
J40-J47 Chronic lower respiratory diseases
0.935 0.065 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.929 0.071 0.000
S90-S99 Injuries to the ankle and foot
0.929 0.071 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.929 0.071 0.000
F33.9 Recurrent depressive disorder, unspecified
0.928 0.072 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.923 0.077 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.920 0.080 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.918 0.082 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.913 0.087 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.909 0.091 0.000
S60-S69 Injuries to the wrist and hand
0.904 0.096 0.000
S40-S49 Injuries to the shoulder and upper arm
0.903 0.097 0.000
M70-M79 Other soft tissue disorders
0.897 0.103 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.896 0.104 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.896 0.104 0.000
T18 Foreign body in alimentary tract
0.895 0.105 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.889 0.111 0.000
M79.7 Fibromyalgia
0.886 0.114 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.886 0.114 0.000
T39.1 4-Aminophenol derivatives
0.884 0.116 0.000
J60-J70 Lung diseases due to external agents
0.882 0.118 0.000
M79.79 Fibromyalgia (Site unspecified)
0.879 0.121 0.000
A49 Bacterial infection of unspecified site
0.867 0.133 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.861 0.139 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.858 0.142 0.000
J69 Pneumonitis due to solids and liquids
0.857 0.143 0.000
M79.0 Rheumatism, unspecified
0.855 0.145 0.000
T39.0 Salicylates
0.854 0.146 0.000
T42.4 Benzodiazepines
0.851 0.149 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.849 0.151 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.847 0.153 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.846 0.154 0.000
S92 Fracture of foot, except ankle
0.845 0.155 0.000
X60-X84 Intentional self-harm
0.841 0.159 0.000
J45 Asthma
0.840 0.160 0.000
J69.0 Pneumonitis due to food and vomit
0.840 0.160 0.000
Chapter VIII Diseases of the ear and mastoid process
0.836 0.164 0.000
T43.2 Other and unspecified antidepressants
0.835 0.165 0.000
F45 Somatoform disorders
0.833 0.167 0.000
T18.1 Foreign body in oesophagus
0.833 0.167 0.000
M80-M85 Disorders of bone density and structure
0.829 0.171 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.825 0.175 0.000
M86-M90 Other osteopathies
0.824 0.175 0.000
S50-S59 Injuries to the elbow and forearm
0.823 0.177 0.000
W20-W49 Exposure to inanimate mechanical forces
0.823 0.177 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.821 0.179 0.000
B35-B49 Mycoses
0.820 0.180 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.819 0.181 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.818 0.182 0.000
T45.1 Antineoplastic and immunosuppressive drugs
0.817 0.183 0.000
X50-X57 Overexertion, travel and privation
0.814 0.186 0.000
F60-F69 Disorders of adult personality and behaviour
0.814 0.186 0.000
T46.5 Other antihypertensive drugs, not elsewhere classified
0.814 0.186 0.000
T00-T07 Injuries involving multiple body regions
0.813 0.187 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.811 0.189 0.000
M79.00 Rheumatism, unspecified (Multiple sites)
0.811 0.189 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.807 0.193 0.000
M40-M43 Deforming dorsopathies
0.807 0.193 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.807 0.193 0.000
F01 Vascular dementia
0.799 0.201 0.000
Y00-Y09 Assault
0.792 0.207 0.000
T46.1 Calcium-channel blockers
0.792 0.208 0.000
T17 Foreign body in respiratory tract
0.786 0.214 0.000
B50-B64 Protozoal diseases
0.785 0.215 0.000
S91 Open wound of ankle and foot
0.784 0.216 0.000
T45.2 Vitamins, not elsewhere classified
0.781 0.219 0.000
F44 Dissociative [conversion] disorders
0.779 0.221 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.778 0.222 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.776 0.224 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.776 0.224 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.775 0.225 0.000
T79-T79 Certain early complications of trauma
0.774 0.226 0.000
A00-A09 Intestinal infectious diseases
0.773 0.227 0.000
A65-A69 Other spirochaetal diseases
0.772 0.228 0.000
F45.8 Other somatoform disorders
0.771 0.228 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.771 0.229 0.000
V10-V19 Pedal cyclist injured in transport accident
0.769 0.231 0.000
M60-M63 Disorders of muscles
0.768 0.232 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.768 0.232 0.000
T45.0 Antiallergic and antiemetic drugs
0.767 0.232 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.766 0.234 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.764 0.236 0.000
F99-F99 Unspecified mental disorder
0.762 0.238 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.762 0.238 0.000
S20-S29 Injuries to the thorax
0.760 0.240 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.760 0.240 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.756 0.244 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.756 0.244 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.753 0.246 0.000
T45.5 Anticoagulants
0.753 0.247 0.000
A41 Other septicaemia
0.749 0.251 0.000
A49.8 Other bacterial infections of unspecified site
0.748 0.252 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.748 0.252 0.000
S43.0 Dislocation of shoulder joint
0.748 0.252 0.000
S64 Injury of nerves at wrist and hand level
0.747 0.253 0.000
W50-W64 Exposure to animate mechanical forces
0.745 0.255 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.745 0.255 0.000
B15-B19 Viral hepatitis
0.744 0.256 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.743 0.256 0.000
H90-H95 Other disorders of ear
0.742 0.258 0.000
S50 Superficial injury of forearm
0.741 0.259 0.000
F52 Sexual dysfunction, not caused by organic disorder or disease
0.741 0.259 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.741 0.259 0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.741 0.259 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.739 0.261 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.739 0.261 0.000
S00-S09 Injuries to the head
0.737 0.263 0.000
A46 Erysipelas
0.737 0.263 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.735 0.265 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.735 0.265 0.000
A40 Streptococcal septicaemia
0.733 0.267 0.000
J45.0 Predominantly allergic asthma
0.732 0.267 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.732 0.268 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.732 0.268 0.000
F01.9 Vascular dementia, unspecified
0.730 0.270 0.000
T18.5 Foreign body in anus and rectum
0.729 0.271 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.728 0.272 0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system
0.728 0.272 0.000
F42 Obsessive-compulsive disorder
0.727 0.273 0.000
V20-V29 Motorcycle rider injured in transport accident
0.725 0.275 0.000
S65 Injury of blood vessels at wrist and hand level
0.723 0.277 0.000
S92.0 Fracture of calcaneus
0.722 0.278 0.000
B99-B99 Other infectious diseases
0.722 0.278 0.000
J46 Status asthmaticus
0.721 0.279 0.000
R47-R49 Symptoms and signs involving speech and voice
0.720 0.280 0.000
X20-X29 Contact with venomous animals and plants
0.719 0.281 0.000
F30 Manic episode
0.718 0.282 0.000
F80-F89 Disorders of psychological development
0.718 0.282 0.000
V40-V49 Car occupant injured in transport accident
0.717 0.283 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.717 0.283 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.717 0.283 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.717 0.283 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.717 0.283 0.000
T36 Poisoning by systemic antibiotics
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
B37 Candidiasis
0.716 0.284 0.000
F02 Dementia in other diseases classified elsewhere
0.714 0.286 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.714 0.286 0.000
F70-F79 Mental retardation
0.714 0.286 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.713 0.287 0.000
Y48 Anaesthetics and therapeutic gases
0.711 0.289 0.000
F38 Other mood [affective] disorders
0.711 0.289 0.000
F34 Persistent mood [affective] disorders
0.711 0.289 0.000
M81 Osteoporosis without pathological fracture
0.710 0.290 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.709 0.291 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.709 0.291 0.000
T46.7 Peripheral vasodilators
0.709 0.291 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.709 0.291 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.709 0.291 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.709 0.291 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.708 0.292 0.000
R47 Speech disturbances, not elsewhere classified
0.708 0.292 0.000
F39 Unspecified mood [affective] disorder
0.707 0.293 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.707 0.293 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.707 0.293 0.000
M85 Other disorders of bone density and structure
0.707 0.293 0.000
H60-H62 Diseases of external ear
0.707 0.293 0.000
M89 Other disorders of bone
0.705 0.295 0.000
H92 Otalgia and effusion of ear
0.705 0.295 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.704 0.296 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.704 0.296 0.000
A75-A79 Rickettsioses
0.704 0.296 0.000
A70-A74 Other diseases caused by chlamydiae
0.704 0.296 0.000
A20-A28 Certain zoonotic bacterial diseases
0.704 0.296 0.000
A15-A19 Tuberculosis
0.704 0.296 0.000
F31.8 Other bipolar affective disorders
0.701 0.299 0.000
F31.7 Bipolar affective disorder, currently in remission
0.701 0.299 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.701 0.299 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.701 0.299 0.000
B65-B83 Helminthiases
0.701 0.299 0.000
S10-S19 Injuries to the neck
0.700 0.300 0.000
M79.1 Myalgia
0.700 0.300 0.000
S60 Superficial injury of wrist and hand
0.698 0.301 0.000
M79.6 Pain in limb
0.698 0.302 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.697 0.303 0.000
S92.1 Fracture of talus
0.697 0.303 0.000
Y42.5 Other oestrogens and progestogens
0.697 0.303 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.697 0.303 0.000
M77 Other enthesopathies
0.695 0.305 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.695 0.305 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.695 0.305 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.694 0.306 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.693 0.307 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.692 0.308 0.000
A41.9 Septicaemia, unspecified
0.692 0.308 0.000
M79.2 Neuralgia and neuritis, unspecified
0.692 0.308 0.000
W21 Striking against or struck by sports equipment
0.690 0.310 0.000
R45 Symptoms and signs involving emotional state
0.690 0.310 0.000
F33.8 Other recurrent depressive disorders
0.690 0.310 0.000
F33.4 Recurrent depressive disorder, currently in remission
0.690 0.310 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.690 0.310 0.000
M43 Other deforming dorsopathies
0.690 0.310 0.000
J45.9 Asthma, unspecified
0.690 0.310 0.000
Y35-Y36 Legal intervention and operations of war
0.688 0.311 0.000
Y10-Y34 Event of undetermined intent
0.688 0.311 0.000
X85-X99 Assault
0.688 0.311 0.000
X30-X39 Exposure to forces of nature
0.688 0.311 0.000
X10-X19 Contact with heat and hot substances
0.688 0.311 0.000
X00-X09 Exposure to smoke, fire and flames
0.688 0.311 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.688 0.311 0.000
W75-W84 Other accidental threats to breathing
0.688 0.311 0.000
W65-W74 Accidental drowning and submersion
0.688 0.311 0.000
V98-V99 Other and unspecified transport accidents
0.688 0.311 0.000
V95-V97 Air and space transport accidents
0.688 0.311 0.000
V90-V94 Water transport accidents
0.688 0.311 0.000
V70-V79 Bus occupant injured in transport accident
0.688 0.311 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.688 0.311 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.688 0.311 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.688 0.311 0.000
V01-V09 Pedestrian injured in transport accident
0.688 0.311 0.000
B00 Herpesviral [herpes simplex] infections
0.686 0.314 0.000
V80-V89 Other land transport accidents
0.686 0.314 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.686 0.314 0.000
T39.4 Antirheumatics, not elsewhere classified
0.686 0.314 0.000
T39.2 Pyrazolone derivatives
0.686 0.314 0.000
S92.3 Fracture of metatarsal bone
0.685 0.315 0.000
A49.9 Bacterial infection, unspecified
0.684 0.316 0.000
F60 Specific personality disorders
0.683 0.317 0.000
A08 Viral and other specified intestinal infections
0.683 0.317 0.000
S50.9 Superficial injury of forearm, unspecified
0.683 0.317 0.000
M87 Osteonecrosis
0.683 0.317 0.000
T19 Foreign body in genito-urinary tract
0.682 0.318 0.000
T15 Foreign body on external eye
0.682 0.318 0.000
T16 Foreign body in ear
0.682 0.318 0.000
A49.0 Staphylococcal infection, unspecified
0.682 0.318 0.000
T01 Open wounds involving multiple body regions
0.681 0.319 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.681 0.319 0.000
A80-A89 Viral infections of the central nervous system
0.680 0.319 0.000
T42.1 Iminostilbenes
0.680 0.320 0.000
T45.9 Primarily systemic and haematological agent, unspecified
0.679 0.321 0.000
T45.8 Other primarily systemic and haematological agents
0.679 0.321 0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.679 0.321 0.000
T45.6 Fibrinolysis-affecting drugs
0.679 0.321 0.000
T45.4 Iron and its compounds
0.679 0.321 0.000
T45.3 Enzymes, not elsewhere classified
0.679 0.321 0.000
R47.8 Other and unspecified speech disturbances
0.679 0.321 0.000
A49.1 Streptococcal infection, unspecified
0.678 0.322 0.000
S59 Other and unspecified injuries of forearm
0.677 0.323 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.676 0.324 0.000
A48 Other bacterial diseases, not elsewhere classified
0.674 0.326 0.000
A44 Bartonellosis
0.674 0.326 0.000
A43 Nocardiosis
0.674 0.326 0.000
A42 Actinomycosis
0.674 0.326 0.000
A39 Meningococcal infection
0.674 0.326 0.000
A37 Whooping cough
0.674 0.326 0.000
A36 Diphtheria
0.674 0.326 0.000
A32 Listeriosis
0.674 0.326 0.000
A31 Infection due to other mycobacteria
0.674 0.326 0.000
A30 Leprosy [Hansen's disease]
0.674 0.326 0.000
A38 Scarlet fever
0.674 0.326 0.000
A35 Other tetanus
0.674 0.326 0.000
A34 Obstetrical tetanus
0.674 0.326 0.000
A33 Tetanus neonatorum
0.674 0.326 0.000
M79.08 Rheumatism, unspecified (Other)
0.673 0.327 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.671 0.329 0.000
H92.0 Otalgia
0.671 0.329 0.000
S02 Fracture of skull and facial bones
0.671 0.329 0.000
J41 Simple and mucopurulent chronic bronchitis
0.670 0.329 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.670 0.330 0.000
T17.2 Foreign body in pharynx
0.670 0.330 0.000
J67 Hypersensitivity pneumonitis due to organic dust
0.670 0.330 0.000
T51 Toxic effect of alcohol
0.670 0.330 0.000
M79.9 Soft tissue disorder, unspecified
0.669 0.331 0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation
0.667 0.333 0.000
S98 Traumatic amputation of ankle and foot
0.666 0.334 0.000
S97 Crushing injury of ankle and foot
0.666 0.334 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.666 0.334 0.000
S95 Injury of blood vessels at ankle and foot level
0.666 0.334 0.000
S94 Injury of nerves at ankle and foot level
0.666 0.334 0.000
F41 Other anxiety disorders
0.665 0.335 0.000
F52.2 Failure of genital response
0.665 0.335 0.000
B25-B34 Other viral diseases
0.665 0.335 0.000
S05 Injury of eye and orbit
0.662 0.338 0.000
T43.9 Psychotropic drug, unspecified
0.662 0.338 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.662 0.338 0.000
T43.6 Psychostimulants with abuse potential
0.662 0.338 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.662 0.338 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.662 0.338 0.000
R42 Dizziness and giddiness
0.662 0.338 0.000
T13 Other injuries of lower limb, level unspecified
0.661 0.339 0.000
X78 Intentional self-harm by sharp object
0.661 0.339 0.000
X50 Overexertion and strenuous or repetitive movements
0.660 0.340 0.000
R45.8 Other symptoms and signs involving emotional state
0.660 0.340 0.000
F48 Other neurotic disorders
0.659 0.341 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.659 0.341 0.000
F00 Dementia in Alzheimer's disease
0.659 0.341 0.000
X51 Travel and motion
0.658 0.341 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.657 0.343 0.000
S91.1 Open wound of toe(s) without damage to nail
0.657 0.343 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.656 0.344 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.655 0.345 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.655 0.345 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.655 0.345 0.000
T42.3 Barbiturates
0.655 0.345 0.000
T42.2 Succinimides and oxazolidinediones
0.655 0.345 0.000
T42.0 Hydantoin derivatives
0.655 0.345 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.654 0.346 0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified
0.654 0.346 0.000
S54 Injury of nerves at forearm level
0.653 0.347 0.000
W44 Foreign body entering into or through eye or natural orifice
0.652 0.348 0.000
S63.6 Sprain and strain of finger(s)
0.652 0.348 0.000
J09-J18 Influenza and pneumonia
0.652 0.348 0.000
T59 Toxic effect of other gases, fumes and vapours
0.652 0.348 0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level
0.650 0.350 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.650 0.350 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.650 0.350 0.000
S68 Traumatic amputation of wrist and hand
0.649 0.351 0.000
S31 Open wound of abdomen, lower back and pelvis
0.649 0.351 0.000
M82 Osteoporosis in diseases classified elsewhere
0.649 0.351 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.649 0.351 0.000
S48 Traumatic amputation of shoulder and upper arm
0.647 0.352 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.647 0.352 0.000
S44 Injury of nerves at shoulder and upper arm level
0.647 0.352 0.000
S41 Open wound of shoulder and upper arm
0.647 0.352 0.000
S47 Crushing injury of shoulder and upper arm
0.647 0.352 0.000
X63.0 Home
0.647 0.353 0.000
B37.8 Candidiasis of other sites
0.647 0.353 0.000
F44.4 Dissociative motor disorders
0.645 0.355 0.000
M76 Enthesopathies of lower limb, excluding foot
0.643 0.356 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.643 0.357 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.643 0.357 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.643 0.357 0.000
F09 Unspecified organic or symptomatic mental disorder
0.643 0.357 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.643 0.357 0.000
M91-M94 Chondropathies
0.642 0.358 0.000
M79.3 Panniculitis, unspecified
0.642 0.358 0.000
M00-M03 Infectious arthropathies
0.642 0.358 0.000
T18.9 Foreign body in alimentary tract, part unspecified
0.641 0.358 0.000
T18.8 Foreign body in other and multiple parts of alimentary tract
0.641 0.358 0.000
T18.4 Foreign body in colon
0.641 0.358 0.000
T18.3 Foreign body in small intestine
0.641 0.358 0.000
T18.2 Foreign body in stomach
0.641 0.358 0.000
T18.0 Foreign body in mouth
0.641 0.358 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.641 0.358 0.000
M79.70 Fibromyalgia (Multiple sites)
0.641 0.359 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.640 0.359 0.000
Y40 Systemic antibiotics
0.640 0.360 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.640 0.360 0.000
Y04 Assault by bodily force
0.639 0.360 0.000
W25 Contact with sharp glass
0.638 0.362 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.637 0.363 0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.637 0.363 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.637 0.363 0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.637 0.363 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.637 0.363 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.637 0.363 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.637 0.363 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.637 0.363 0.000
T44.0 Anticholinesterase agents
0.637 0.363 0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system
0.636 0.364 0.000
S43.1 Dislocation of acromioclavicular joint
0.635 0.365 0.000
M79.78 Fibromyalgia (Other)
0.635 0.365 0.000
M79.77 Fibromyalgia (Ankle and foot)
0.635 0.365 0.000
M79.76 Fibromyalgia (Lower leg)
0.635 0.365 0.000
M79.75 Fibromyalgia (Pelvic region and thigh)
0.635 0.365 0.000
M79.74 Fibromyalgia (Hand)
0.635 0.365 0.000
M79.73 Fibromyalgia (Forearm)
0.635 0.365 0.000
M79.72 Fibromyalgia (Upper arm)
0.635 0.365 0.000
M79.71 Fibromyalgia (Shoulder region)
0.635 0.365 0.000
B01 Varicella [chickenpox]
0.634 0.366 0.000
S92.00 Fracture of calcaneus (closed)
0.633 0.367 0.000
B59 Pneumocystosis
0.633 0.367 0.000
J70 Respiratory conditions due to other external agents
0.633 0.367 0.000
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours
0.633 0.367 0.000
J66 Airway disease due to specific organic dust
0.633 0.367 0.000
J63 Pneumoconiosis due to other inorganic dusts
0.633 0.367 0.000
J62 Pneumoconiosis due to dust containing silica
0.633 0.367 0.000
J65 Pneumoconiosis associated with tuberculosis
0.633 0.367 0.000
J64 Unspecified pneumoconiosis
0.633 0.367 0.000
J60 Coalworker's pneumoconiosis
0.633 0.367 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.632 0.368 0.000
X60 Intentional self-poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics
0.630 0.370 0.000
S49.9 Unspecified injury of shoulder and upper arm
0.629 0.371 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.629 0.371 0.000
M50-M54 Other dorsopathies
0.629 0.371 0.000
B37.0 Candidal stomatitis
0.629 0.371 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.628 0.372 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.626 0.374 0.000
M60 Myositis
0.626 0.374 0.000
B02 Zoster [herpes zoster]
0.625 0.375 0.000
M40 Kyphosis and lordosis
0.624 0.376 0.000
M88 Paget's disease of bone [osteitis deformans]
0.624 0.376 0.000
S36 Injury of intra-abdominal organs
0.622 0.378 0.000
A69 Other spirochaetal infections
0.622 0.378 0.000
A49.3 Mycoplasma infection, unspecified
0.622 0.378 0.000
A49.2 Haemophilus influenzae infection, unspecified
0.622 0.378 0.000
S64.1 Injury of median nerve at wrist and hand level
0.622 0.378 0.000
B35 Dermatophytosis
0.621 0.379 0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level
0.621 0.379 0.000
S99 Other and unspecified injuries of ankle and foot
0.618 0.381 0.000
Q50-Q56 Congenital malformations of genital organs
0.618 0.382 0.000
M43.1 Spondylolisthesis
0.618 0.382 0.000
T38.9 Other and unspecified hormone antagonists
0.617 0.382 0.000
T38.8 Other and unspecified hormones and their synthetic substitutes
0.617 0.382 0.000
T38.7 Androgens and anabolic congeners
0.617 0.382 0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.617 0.382 0.000
T38.5 Other oestrogens and progestogens
0.617 0.382 0.000
T38.4 Oral contraceptives
0.617 0.382 0.000
T38.2 Antithyroid drugs
0.617 0.382 0.000
T38.1 Thyroid hormones and substitutes
0.617 0.382 0.000
T38.0 Glucocorticoids and synthetic analogues
0.617 0.382 0.000
W22 Striking against or struck by other objects
0.617 0.383 0.000
T56 Toxic effect of metals
0.617 0.383 0.000
M79.5 Residual foreign body in soft tissue
0.616 0.384 0.000
Y00 Assault by blunt object
0.616 0.384 0.000
M81.9 Osteoporosis, unspecified
0.616 0.384 0.000
T50.8 Diagnostic agents
0.615 0.385 0.000
T50.7 Analeptics and opioid receptor antagonists
0.615 0.385 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.615 0.385 0.000
T50.5 Appetite depressants
0.615 0.385 0.000
T50.4 Drugs affecting uric acid metabolism
0.615 0.385 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.615 0.385 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.615 0.385 0.000
T50.1 Loop [high-ceiling] diuretics
0.615 0.385 0.000
T50.0 Mineralocorticoids and their antagonists
0.615 0.385 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.615 0.385 0.000
J69.8 Pneumonitis due to other solids and liquids
0.615 0.385 0.000
J69.1 Pneumonitis due to oils and essences
0.615 0.385 0.000
R46 Symptoms and signs involving appearance and behaviour
0.615 0.385 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.614 0.386 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.614 0.386 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.614 0.386 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.614 0.386 0.000
F44.5 Dissociative convulsions
0.614 0.386 0.000
M41 Scoliosis
0.614 0.386 0.000
T66-T78 Other and unspecified effects of external causes
0.614 0.386 0.000
M79.07 Rheumatism, unspecified (Ankle and foot)
0.613 0.387 0.000
M79.06 Rheumatism, unspecified (Lower leg)
0.613 0.387 0.000
M79.05 Rheumatism, unspecified (Pelvic region and thigh)
0.613 0.387 0.000
M79.04 Rheumatism, unspecified (Hand)
0.613 0.387 0.000
M79.03 Rheumatism, unspecified (Forearm)
0.613 0.387 0.000
M79.02 Rheumatism, unspecified (Upper arm)
0.613 0.387 0.000
M79.01 Rheumatism, unspecified (Shoulder region)
0.613 0.387 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.612 0.388 0.000
M79.19 Myalgia (Site unspecified)
0.611 0.388 0.000
S93.3 Dislocation of other and unspecified parts of foot
0.611 0.389 0.000
F43 Reaction to severe stress, and adjustment disorders
0.611 0.389 0.000
H61 Other disorders of external ear
0.609 0.391 0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level
0.609 0.391 0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level
0.609 0.391 0.000
F53 Mental and behavioural disorders associated with the puerperium, not elsewhere classified
0.608 0.392 0.000
F51 Nonorganic sleep disorders
0.608 0.392 0.000
F50 Eating disorders
0.608 0.392 0.000
F59 Unspecified behavioural syndromes associated with physiological disturbances and physical factors
0.608 0.392 0.000
F55 Abuse of non-dependence-producing substances
0.608 0.392 0.000
F54 Psychological and behavioural factors associated with disorders or diseases classified elsewhere
0.608 0.392 0.000
T21 Burn and corrosion of trunk
0.608 0.392 0.000
T11 Other injuries of upper limb, level unspecified
0.606 0.393 0.000
Y59 Other and unspecified vaccines and biological substances
0.606 0.394 0.000
Y58 Bacterial vaccines
0.606 0.394 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.606 0.394 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.606 0.394 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.606 0.394 0.000
S92.9 Fracture of foot, unspecified
0.606 0.394 0.000
S92.7 Multiple fractures of foot
0.606 0.394 0.000
S92.5 Fracture of other toe
0.606 0.394 0.000
S92.4 Fracture of great toe
0.606 0.394 0.000
M77.9 Enthesopathy, unspecified
0.604 0.396 0.000
S91.3 Open wound of other parts of foot
0.604 0.396 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.603 0.396 0.000
M62 Other disorders of muscle
0.603 0.397 0.000
A02 Other Salmonella infections
0.603 0.397 0.000
S32 Fracture of lumbar spine and pelvis
0.603 0.397 0.000
X84 Intentional self-harm by unspecified means
0.603 0.397 0.000
X83 Intentional self-harm by other specified means
0.603 0.397 0.000
X82 Intentional self-harm by crashing of motor vehicle
0.603 0.397 0.000
X81 Intentional self-harm by jumping or lying before moving object
0.603 0.397 0.000
X80 Intentional self-harm by jumping from a high place
0.603 0.397 0.000
X79 Intentional self-harm by blunt object
0.603 0.397 0.000
X77 Intentional self-harm by steam, hot vapours and hot objects
0.603 0.397 0.000
X76 Intentional self-harm by smoke, fire and flames
0.603 0.397 0.000
X75 Intentional self-harm by explosive material
0.603 0.397 0.000
X74 Intentional self-harm by other and unspecified firearm discharge
0.603 0.397 0.000
X73 Intentional self-harm by rifle, shotgun and larger firearm discharge
0.603 0.397 0.000
X72 Intentional self-harm by handgun discharge
0.603 0.397 0.000
X71 Intentional self-harm by drowning and submersion
0.603 0.397 0.000
X70 Intentional self-harm by hanging, strangulation and suffocation
0.603 0.397 0.000
X69 Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
0.603 0.397 0.000
X68 Intentional self-poisoning by and exposure to pesticides
0.603 0.397 0.000
X67 Intentional self-poisoning by and exposure to other gases and vapours
0.603 0.397 0.000
X66 Intentional self-poisoning by and exposure to organic solvents and halogenated hydrocarbons and their vapours
0.603 0.397 0.000
X65 Intentional self-poisoning by and exposure to alcohol
0.603 0.397 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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