TreeWAS – Variant ID: rs111969884

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
I25.2 Old myocardial infarction	1.000	0.000
I25 Chronic ischaemic heart disease	1.000	0.000
I20 Angina pectoris	1.000	0.000
I20-I25 Ischaemic heart diseases	1.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000
# Top node	1.000	0.000
I25.8 Other forms of chronic ischaemic heart disease	1.000	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	1.000	0.000
E70-E90 Metabolic disorders	1.000	0.000
I20.0 Unstable angina	1.000	0.000
I73 Other peripheral vascular diseases	0.998	0.002
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.998	0.002
I21 Acute myocardial infarction	0.997	0.003
E10-E14 Diabetes mellitus	0.997	0.003
I73.9 Peripheral vascular disease, unspecified	0.997	0.003
E78.5 Hyperlipidaemia, unspecified	0.996	0.004
Chapter XII Diseases of the skin and subcutaneous tissue	0.995	0.005
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.991	0.009
E14 Unspecified diabetes mellitus	0.991	0.009
L80-L99 Other disorders of the skin and subcutaneous tissue	0.990	0.010
I25.1 Atherosclerotic heart disease	0.988	0.012
M50-M54 Other dorsopathies	0.985	0.015
I74 Arterial embolism and thrombosis	0.980	0.020
I20.9 Angina pectoris, unspecified	0.980	0.020
I21.4 Acute subendocardial myocardial infarction	0.975	0.025
E14.9 Without complications	0.975	0.025
M51 Other intervertebral disk disorders	0.971	0.029
E87 Other disorders of fluid, electrolyte and acid-base balance	0.968	0.032
L90 Atrophic disorders of skin	0.961	0.039
M51.2 Other specified intervertebral disk displacement	0.958	0.042
L91 Hypertrophic disorders of skin	0.955	0.045
L89 Decubitus ulcer	0.953	0.047
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.947	0.053
E87.2 Acidosis	0.946	0.054
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.942	0.058
I20.8 Other forms of angina pectoris	0.940	0.060
I21.1 Acute transmural myocardial infarction of inferior wall	0.938	0.062
M86-M90 Other osteopathies	0.938	0.062
E10 Insulin-dependent diabetes mellitus	0.937	0.063
L90.5 Scar conditions and fibrosis of skin	0.936	0.064
L91.8 Other hypertrophic disorders of skin	0.917	0.083
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.913	0.087
E80 Disorders of porphyrin and bilirubin metabolism	0.910	0.090
S32 Fracture of lumbar spine and pelvis	0.906	0.094
E20-E35 Disorders of other endocrine glands	0.898	0.102
I25.9 Chronic ischaemic heart disease, unspecified	0.897	0.103
E87.5 Hyperkalaemia	0.895	0.105
I25.3 Aneurysm of heart	0.892	0.108
E87.6 Hypokalaemia	0.891	0.109
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.889	0.111
L00-L08 Infections of the skin and subcutaneous tissue	0.887	0.113
E14.3 With ophthalmic complications	0.887	0.113
Chapter XX External causes of morbidity and mortality	0.885	0.115
L97 Ulcer of lower limb, not elsewhere classified	0.879	0.121
I21.2 Acute transmural myocardial infarction of other sites	0.877	0.123
E10.9 Without complications	0.875	0.125
T20-T25 Burns and corrosions of external body surface, specified by site	0.874	0.126
L50-L54 Urticaria and erythema	0.874	0.126
I78 Diseases of capillaries	0.872	0.128
M54 Dorsalgia	0.871	0.129
S30 Superficial injury of abdomen, lower back and pelvis	0.866	0.134
Chapter X Diseases of the respiratory system	0.865	0.135
I74.5 Embolism and thrombosis of iliac artery	0.865	0.135
L89.1 Stage II decubitus ulcer	0.863	0.137
L89.0 Stage I decubitus ulcer and pressure area	0.858	0.142
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.855	0.145
Chapter XXII Codes for special purposes	0.854	0.146
J95-J99 Other diseases of the respiratory system	0.853	0.147
J98 Other respiratory disorders	0.848	0.152
M60-M63 Disorders of muscles	0.847	0.153
L03 Cellulitis	0.834	0.166
I20.1 Angina pectoris with documented spasm	0.826	0.174
S32.5 Fracture of pubis	0.819	0.181
S20-S29 Injuries to the thorax	0.815	0.185
E10.0 With coma	0.814	0.186
E88 Other metabolic disorders	0.811	0.189
M20-M25 Other joint disorders	0.811	0.189
E78.2 Mixed hyperlipidaemia	0.809	0.191
I73.0 Raynaud's syndrome	0.805	0.195
E80.4 Gilbert's syndrome	0.805	0.195
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.804	0.196
M50 Cervical disk disorders	0.801	0.199
J98.1 Pulmonary collapse	0.797	0.203
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.797	0.203
L94 Other localised connective tissue disorders	0.796	0.204
J60-J70 Lung diseases due to external agents	0.795	0.205
M90 Osteopathies in diseases classified elsewhere	0.793	0.207
J98.4 Other disorders of lung	0.792	0.208
L03.1 Cellulitis of other parts of limb	0.789	0.211
I25.5 Ischaemic cardiomyopathy	0.788	0.212
Chapter VI Diseases of the nervous system	0.787	0.213
I78.1 Naevus, nonneoplastic	0.780	0.220
E14.4 With neurological complications	0.779	0.220
M00-M03 Infectious arthropathies	0.779	0.221
L91.0 Keloid scar	0.778	0.222
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.777	0.223
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.776	0.224
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.773	0.227
M80-M85 Disorders of bone density and structure	0.773	0.227
M54.5 Low back pain	0.770	0.230
E23 Hypofunction and other disorders of pituitary gland	0.767	0.233
J40-J47 Chronic lower respiratory diseases	0.766	0.234
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.765	0.235
T92 Sequelae of injuries of upper limb	0.764	0.236
M54.59 Low back pain (Site unspecified)	0.761	0.239
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.761	0.239
E10.3 With ophthalmic complications	0.761	0.239
M89 Other disorders of bone	0.759	0.241
V10-V19 Pedal cyclist injured in transport accident	0.758	0.242
M88 Paget's disease of bone [osteitis deformans]	0.757	0.243
M87 Osteonecrosis	0.756	0.244
T91 Sequelae of injuries of neck and trunk	0.756	0.244
S32.50 Fracture of pubis (closed)	0.756	0.244
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.755	0.245
I73.8 Other specified peripheral vascular diseases	0.754	0.246
I74.8 Embolism and thrombosis of other arteries	0.753	0.247
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.752	0.248
E80.6 Other disorders of bilirubin metabolism	0.752	0.248
T98 Sequelae of other and unspecified effects of external causes	0.747	0.253
W20-W49 Exposure to inanimate mechanical forces	0.747	0.253
S30.0 Contusion of lower back and pelvis	0.746	0.254
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.746	0.254
S27 Injury of other and unspecified intrathoracic organs	0.744	0.256
M62 Other disorders of muscle	0.744	0.256
L52 Erythema nodosum	0.744	0.256
J69 Pneumonitis due to solids and liquids	0.743	0.257
M40-M43 Deforming dorsopathies	0.742	0.258
E85 Amyloidosis	0.742	0.258
G40-G47 Episodic and paroxysmal disorders	0.739	0.261
L89.9 Decubitus ulcer and pressure area, unspecified	0.738	0.261
L90.0 Lichen sclerosus et atrophicus	0.735	0.265
E78.0 Pure hypercholesterolaemia	0.735	0.265
S32.4 Fracture of acetabulum	0.734	0.266
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.732	0.268
S36 Injury of intra-abdominal organs	0.731	0.269
S31 Open wound of abdomen, lower back and pelvis	0.731	0.269
I21.9 Acute myocardial infarction, unspecified	0.730	0.270
W00-W19 Falls	0.728	0.272
E83 Disorders of mineral metabolism	0.728	0.272
I70 Atherosclerosis	0.728	0.272
E50-E64 Other nutritional deficiencies	0.727	0.273
W50-W64 Exposure to animate mechanical forces	0.727	0.273
S90-S99 Injuries to the ankle and foot	0.726	0.273
S70-S79 Injuries to the hip and thigh	0.726	0.274
M54.3 Sciatica	0.723	0.277
T15-T19 Effects of foreign body entering through natural orifice	0.722	0.278
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.721	0.279
S32.3 Fracture of ilium	0.721	0.279
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.721	0.279
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.720	0.280
E78.9 Disorder of lipoprotein metabolism, unspecified	0.720	0.280
I25.6 Silent myocardial ischaemia	0.717	0.283
I25.4 Coronary artery aneurysm	0.717	0.283
I25.0 Atherosclerotic cardiovascular disease, so described	0.717	0.283
I23 Certain current complications following acute myocardial infarction	0.717	0.283
I00-I02 Acute rheumatic fever	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
E84 Cystic fibrosis	0.717	0.283
E79 Disorders of purine and pyrimidine metabolism	0.717	0.283
E77 Disorders of glycoprotein metabolism	0.717	0.283
E76 Disorders of glycosaminoglycan metabolism	0.717	0.283
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.717	0.283
E74 Other disorders of carbohydrate metabolism	0.717	0.283
E72 Other disorders of amino-acid metabolism	0.717	0.283
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.717	0.283
E70 Disorders of aromatic amino-acid metabolism	0.717	0.283
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.717	0.283
I73.1 Thromboangiitis obliterans [Buerger]	0.716	0.284
E78.6 Lipoprotein deficiency	0.715	0.285
E78.3 Hyperchylomicronaemia	0.715	0.285
I21.X Presumed acute myicardial infaction (unconfirmed)	0.715	0.285
I21.3 Acute transmural myocardial infarction of unspecified site	0.715	0.285
E12 Malnutrition-related diabetes mellitus	0.715	0.285
I74.9 Embolism and thrombosis of unspecified artery	0.714	0.286
G35-G37 Demyelinating diseases of the central nervous system	0.714	0.286
L10-L14 Bullous disorders	0.713	0.287
M50.0 Cervical disk disorder with myelopathy	0.712	0.288
S32.1 Fracture of sacrum	0.712	0.288
L84 Corns and callosities	0.712	0.288
M86 Osteomyelitis	0.712	0.288
L93 Lupus erythematosus	0.712	0.288
E14.8 With unspecified complications	0.710	0.290
E14.7 With multiple complications	0.710	0.290
E14.6 With other specified complications	0.710	0.290
E14.5 With peripheral circulatory complications	0.710	0.290
E14.2 Withrenal complications	0.710	0.290
E14.1 With ketoacidosis	0.710	0.290
E14.0 With coma	0.710	0.290
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.710	0.290
L87 Transepidermal elimination disorders	0.710	0.290
L88 Pyoderma gangrenosum	0.710	0.290
L86 Keratoderma in diseases classified elsewhere	0.710	0.290
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.708	0.292
J98.9 Respiratory disorder, unspecified	0.708	0.292
E73 Lactose intolerance	0.706	0.294
G44 Other headache syndromes	0.706	0.294
J69.0 Pneumonitis due to food and vomit	0.706	0.294
E22 Hyperfunction of pituitary gland	0.704	0.296
M51.8 Other specified intervertebral disk disorders	0.703	0.297
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.703	0.297
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.703	0.297
I74.0 Embolism and thrombosis of abdominal aorta	0.703	0.297
T79-T79 Certain early complications of trauma	0.703	0.297
L95 Vasculitis limited to skin, not elsewhere classified	0.700	0.300
E21.0 Primary hyperparathyroidism	0.700	0.300
T00-T07 Injuries involving multiple body regions	0.697	0.303
M51.9 Intervertebral disk disorder, unspecified	0.697	0.303
T90 Sequelae of injuries of head	0.696	0.304
M51.3 Other specified intervertebral disk degeneration	0.696	0.304
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy	0.696	0.304
M51.4 Schmorl's nodes	0.696	0.304
Y88 Sequelae of surgical and medical care as external cause	0.696	0.304
J44 Other chronic obstructive pulmonary disease	0.695	0.305
E87.4 Mixed disorder of acid-base balance	0.694	0.306
J44.8 Other specified chronic obstructive pulmonary disease	0.694	0.306
L04 Acute lymphadenitis	0.694	0.306
G40 Epilepsy	0.691	0.309
L80 Vitiligo	0.691	0.309
L53 Other erythematous conditions	0.690	0.310
V40-V49 Car occupant injured in transport accident	0.690	0.310
L90.9 Atrophic disorder of skin, unspecified	0.689	0.311
L90.8 Other atrophic disorders of skin	0.689	0.311
L90.6 Striae atrophicae	0.689	0.311
L90.4 Acrodermatitis chronica atrophicans	0.689	0.311
L90.3 Atrophoderma of Pasini and Pierini	0.689	0.311
L90.2 Anetoderma of Jadassohn-Pellizzari	0.689	0.311
L90.1 Anetoderma of Schweninger-Buzzi	0.689	0.311
E34 Other endocrine disorders	0.686	0.314
M54.8 Other dorsalgia	0.686	0.314
L91.9 Hypertrophic disorder of skin, unspecified	0.685	0.315
E23.0 Hypopituitarism	0.685	0.315
M23 Internal derangement of knee	0.684	0.316
L89.3 Stage IV decubitus ulcer	0.683	0.317
M50.9 Cervical disk disorder, unspecified	0.683	0.317
S27.2 Traumatic heamopneumothorax	0.683	0.317
T20 Burn and corrosion of head and neck	0.682	0.318
T23 Burn and corrosion of wrist and hand	0.682	0.318
J67 Hypersensitivity pneumonitis due to organic dust	0.681	0.319
T14 Injury of unspecified body region	0.680	0.320
E10.5 With peripheral circulatory complications	0.679	0.321
T33-T35 Frostbite	0.679	0.321
T26-T28 Burns and corrosions confined to eye and internal organs	0.679	0.321
L03.9 Cellulitis, unspecified	0.679	0.321
E78.1 Pure hyperglyceridaemia	0.677	0.322
S32.80 Fracture of other and unspecified parts of lumbar spine and pelvis (closed)	0.678	0.322
W75-W84 Other accidental threats to breathing	0.677	0.323
J43 Emphysema	0.676	0.324
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.675	0.325
S37 Injury of urinary and pelvic organs	0.675	0.325
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.675	0.325
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.675	0.325
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.675	0.325
I21.0 Acute transmural myocardial infarction of anterior wall	0.675	0.325
J98.6 Disorders of diaphragm	0.674	0.326
M53 Other dorsopathies, not elsewhere classified	0.673	0.327
E10.8 With unspecified complications	0.672	0.328
E10.7 With multiple complications	0.672	0.328
E10.6 With other specified complications	0.672	0.328
E10.2 With renal complications	0.672	0.328
E78.4 Other hyperlipidaemia	0.671	0.329
J98.0 Diseases of bronchus, not elsewhere classified	0.671	0.329
M62.8 Other specified disorders of muscle	0.670	0.330
E27 Other disorders of adrenal gland	0.669	0.331
M21 Other acquired deformities of limbs	0.667	0.333
V18 Pedal cyclist injured in noncollision transport accident	0.666	0.334
G44.2 Tension-type headache	0.665	0.335
L89.2 Stage III decubitus ulcer	0.663	0.337
V80-V89 Other land transport accidents	0.662	0.338
X50-X57 Overexertion, travel and privation	0.660	0.340
M24 Other specific joint derangements	0.659	0.341
S30.1 Contusion of abdominal wall	0.658	0.342
L94.0 Localised scleroderma [morphea]	0.657	0.343
X40-X49 Accidental poisoning by and exposure to noxious substances	0.657	0.343
M65-M68 Disorders of synovium and tendon	0.655	0.344
X58-X59 Accidental exposure to other and unspecified factors	0.655	0.345
I77 Other disorders of arteries and arterioles	0.655	0.345
M89.3 Hypertrophy of bone	0.655	0.345
E26 Hyperaldosteronism	0.655	0.345
G35 Multiple sclerosis	0.655	0.345
M84 Disorders of continuity of bone	0.654	0.346
M31 Other necrotising vasculopathies	0.654	0.346
X60-X84 Intentional self-harm	0.653	0.347
E80.7 Disorder of bilirubin metabolism, unspecified	0.652	0.348
E80.5 Crigler-Najjar syndrome	0.652	0.348
E80.3 Defects of catalase and peroxydase	0.652	0.348
E80.2 Other porphyria	0.652	0.348
E80.1 Porphyria cutanea tarda	0.652	0.348
E80.0 Hereditary erythropoietic porphyria	0.652	0.348
M34 Systemic sclerosis	0.650	0.350
S32.2 Fracture of coccyx	0.650	0.350
Y00-Y09 Assault	0.648	0.352
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.648	0.352
M91-M94 Chondropathies	0.647	0.353
L51 Erythema multiforme	0.647	0.353
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.646	0.353
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.646	0.354
E88.2 Lipomatosis, not elsewhere classified	0.645	0.355
L92 Granulomatous disorders of skin and subcutaneous tissue	0.645	0.355
E35 Disorders of endocrine glands in diseases classified elsewhere	0.644	0.356
E32 Diseases of thymus	0.644	0.356
E31 Polyglandular dysfunction	0.644	0.356
E30 Disorders of puberty, not elsewhere classified	0.644	0.356
E25 Adrenogenital disorders	0.644	0.356
E20 Hypoparathyroidism	0.644	0.356
S30.2 Contusion of external genital organs	0.644	0.356
Chapter V Mental and behavioural disorders	0.643	0.357
M90.7 Fracture of bone in neoplastic disease	0.642	0.358
E40-E46 Malnutrition	0.639	0.360
M90.1 Periostitis in other infectious diseases classified elsewhere	0.639	0.361
E28 Ovarian dysfunction	0.639	0.361
E83.1 Disorders of iron metabolism	0.639	0.361
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure	0.639	0.361
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.639	0.361
L03.8 Cellulitis of other sites	0.638	0.361
G20-G26 Extrapyramidal and movement disorders	0.638	0.362
T95 Sequelae of burns, corrosions and frostbite	0.637	0.363
T94 Sequelae of injuries involving multiple and unspecified body regions	0.637	0.363
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.637	0.363
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.637	0.363
E13 Other specified diabetes mellitus	0.637	0.363
L01 Impetigo	0.636	0.364
L00 Staphylococcal scalded skin syndrome	0.636	0.364
E87.7 Fluid overload	0.635	0.365
I05-I09 Chronic rheumatic heart diseases	0.635	0.365
Y35-Y36 Legal intervention and operations of war	0.635	0.365
Y10-Y34 Event of undetermined intent	0.635	0.365
X85-X99 Assault	0.635	0.365
X30-X39 Exposure to forces of nature	0.635	0.365
X10-X19 Contact with heat and hot substances	0.635	0.365
X00-X09 Exposure to smoke, fire and flames	0.635	0.365
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.635	0.365
W65-W74 Accidental drowning and submersion	0.635	0.365
V98-V99 Other and unspecified transport accidents	0.635	0.365
V95-V97 Air and space transport accidents	0.635	0.365
V90-V94 Water transport accidents	0.635	0.365
V70-V79 Bus occupant injured in transport accident	0.635	0.365
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.635	0.365
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.635	0.365
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.635	0.365
V01-V09 Pedestrian injured in transport accident	0.635	0.365
J40 Bronchitis, not specified as acute or chronic	0.635	0.365
L50 Urticaria	0.634	0.366
M23.3 Other meniscus derangements	0.634	0.366
E78.8 Other disorders of lipoprotein metabolism	0.633	0.367
T91.9 Sequelae of unspecified injury of neck and trunk	0.632	0.367
L02 Cutaneous abscess, furuncle and carbuncle	0.632	0.368
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.632	0.368
L03.2 Cellulitis of face	0.631	0.369
J80-J84 Other respiratory diseases principally affecting the interstitium	0.630	0.370
J46 Status asthmaticus	0.630	0.370
S50-S59 Injuries to the elbow and forearm	0.630	0.370
L20-L30 Dermatitis and eczema	0.629	0.371
M88.9 Paget's disease of bone, unspecified	0.628	0.372
M00 Pyogenic arthritis	0.627	0.372
T25 Burn and corrosion of ankle and foot	0.627	0.373
T21 Burn and corrosion of trunk	0.627	0.373
L54 Erythema in diseases classified elsewhere	0.627	0.373
I78.9 Disease of capillaries, unspecified	0.625	0.375
I78.8 Other diseases of capillaries	0.625	0.375
I78.0 Hereditary haemorrhagic telangiectasia	0.625	0.375
M54.0 Panniculitis affecting regions of neck and back	0.624	0.375
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.624	0.376
M54.4 Lumbago with sciatica	0.624	0.376
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis	0.621	0.379
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.619	0.381
M54.6 Pain in thoracic spine	0.618	0.381
J99 Respiratory disorders in diseases classified elsewhere	0.617	0.383
X20-X29 Contact with venomous animals and plants	0.617	0.383
G41 Status epilepticus	0.615	0.385
E10.1 With ketoacidosis	0.615	0.385
M87.8 Other osteonecrosis	0.615	0.385
M54.39 Sciatica (Site unspecified)	0.614	0.386
V18.0 Driver injured in nontraffic accident	0.614	0.386
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.613	0.387
I79.1 Aortitis in diseases classified elsewhere	0.613	0.387
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.613	0.387
E65-E68 Obesity and other hyperalimentation	0.613	0.387
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.612	0.388
J96 Respiratory failure, not elsewhere classified	0.612	0.388
V20-V29 Motorcycle rider injured in transport accident	0.612	0.388
S32.40 Fracture of acetabulum (closed)	0.610	0.389
E11 Non-insulin-dependent diabetes mellitus	0.610	0.390
J43.9 Emphysema, unspecified	0.610	0.390
I27 Other pulmonary heart diseases	0.610	0.390
T92.2 Sequelae of fracture at wrist and hand level	0.609	0.391
M85 Other disorders of bone density and structure	0.609	0.391
J98.5 Diseases of mediastinum, not elsewhere classified	0.608	0.392
J98.3 Compensatory emphysema	0.608	0.392
J98.2 Interstitial emphysema	0.608	0.392
M63 Disorders of muscle in diseases classified elsewhere	0.607	0.392
M61 Calcification and ossification of muscle	0.607	0.392
M60 Myositis	0.607	0.392
M30 Polyarteritis nodosa and related conditions	0.605	0.395
I71 Aortic aneurysm and dissection	0.605	0.395
T18 Foreign body in alimentary tract	0.604	0.396
U88 Agent resistant to multiple antibiotics	0.603	0.397
L81 Other disorders of pigmentation	0.602	0.398
Y89 Sequelae of other external causes	0.602	0.398
T11 Other injuries of upper limb, level unspecified	0.601	0.398
M54.9 Dorsalgia, unspecified	0.601	0.399
Y86 Sequelae of other accidents	0.600	0.400
T22.0 Burn of unspecified degree of shoulder and upper limb, except wrist and hand	0.599	0.401
S32.0 Fracture of lumbar vertebra	0.598	0.402
S39.0 Injury of muscle and tendon of abdomen, lower back and pelvis	0.598	0.402
T14.0 Superficial injury of unspecified body region	0.597	0.403
M32 Systemic lupus erythematosus	0.596	0.404
E61 Deficiency of other nutrient elements	0.596	0.404
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.595	0.405
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.595	0.405
E83.3 Disorders of phosphorus metabolism	0.595	0.405
S27.3 Other injuries of lung	0.594	0.406
G44.4 Drug-induced headache, not elsewhere classified	0.594	0.406
L83 Acanthosis nigricans	0.594	0.406
T91.1 Sequelae of fracture of spine	0.593	0.407
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.593	0.407
M24.4 Recurrent dislocation and subluxation of joint	0.593	0.407
W57 Bitten or stung by non-venomous insect and other non-venomous arthropods	0.592	0.408
S91 Open wound of ankle and foot	0.591	0.409
U89 Agent resistant to other and unspecified antibiotics	0.591	0.409
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.590	0.410
T24.3 Burn of third degree of hip and lower limb, except ankle and foot	0.589	0.411
T92.1 Sequelae of fracture of arm	0.589	0.411
L85 Other epidermal thickening	0.589	0.411
S32.30 Fracture of ilium (closed)	0.588	0.412
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.587	0.412
S32.51 Fracture of pubis (open)	0.587	0.413
G40.7 Petit mal, unspecified, without grand mal seizures	0.586	0.414
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.585	0.415
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.585	0.415
S29 Other and unspecified injuries of thorax	0.585	0.415
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.584	0.415
S26 Injury of heart	0.584	0.415
S25 Injury of blood vessels of thorax	0.584	0.415
S24 Injury of nerves and spinal cord at thorax level	0.584	0.415
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.584	0.415
S21 Open wound of thorax	0.584	0.415
M54.50 Low back pain (Multiple sites in spine)	0.584	0.416
W22 Striking against or struck by other objects	0.583	0.416
M50.2 Other cervical disk displacement	0.583	0.417
W45 Foreign body or object entering through skin	0.583	0.417
S32.7 Multiple fractures of lumbar spine and pelvis	0.583	0.417
T91.8 Sequelae of other specified injuries of neck and trunk	0.582	0.418
E88.9 Metabolic disorder, unspecified	0.582	0.418
E88.8 Other specified metabolic disorders	0.582	0.418
E88.3 Tumour lysis syndrome	0.582	0.418
E88.1 Lipodystrophy, not elsewhere classified	0.582	0.418
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.581	0.418
M33 Dermatopolymyositis	0.581	0.418
S10-S19 Injuries to the neck	0.580	0.420
M89.37 Hypertrophy of bone (Ankle and foot)	0.580	0.420
S36.1 Injury of liver or gallbladder	0.580	0.420
S31.4 Open wound of vagina and vulva	0.579	0.421
Y60-Y69 Misadventures to patients during surgical and medical care	0.579	0.421
E22.0 Acromegaly and pituitary gigantism	0.578	0.422
J98.8 Other specified respiratory disorders	0.578	0.422
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.577	0.423
T92.8 Sequelae of other specified injuries of upper limb	0.577	0.423
W15 Fall from cliff	0.577	0.423
W02 Fall involving ice-skates, skis, roller-skates or skateboards	0.575	0.425
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.575	0.425
M82 Osteoporosis in diseases classified elsewhere	0.575	0.425
M50.8 Other cervical disk disorders	0.574	0.426
E24 Cushing's syndrome	0.573	0.426
M43 Other deforming dorsopathies	0.573	0.427
S32.10 Fracture of sacrum (closed)	0.573	0.427
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.573	0.427
T90.8 Sequelae of other specified injuries of head	0.573	0.427
W13 Fall from, out of or through building or structure	0.572	0.428
T09 Other injuries of spine and trunk, level unspecified	0.571	0.428
T12.X1 Fracture of lower limb, level unspecified (open)	0.571	0.428
T12.X0 Fracture of lower limb, level unspecified (closed)	0.571	0.428
T12 Fracture of lower limb, level unspecified	0.571	0.428
T10.X1 Fracture of upper limb, level unspecified (open)	0.571	0.428
T10.X0 Fracture of upper limb, level unspecified (closed)	0.571	0.428
T10 Fracture of upper limb, level unspecified	0.571	0.428
T08.X1 Fracture of spine, level unspecified (open)	0.571	0.428
T08.X0 Fracture of spine, level unspecified (closed)	0.571	0.428
T08 Fracture of spine, level unspecified	0.571	0.428
T92.0 Sequelae of open wound of upper limb	0.571	0.429
L94.9 Localised connective tissue disorder, unspecified	0.571	0.429
L94.8 Other specified localised connective tissue disorders	0.571	0.429
L94.6 Ainhum	0.571	0.429
L94.5 Poikiloderma vasculare atrophicans	0.571	0.429
L94.4 Gottron's papules	0.571	0.429
L94.3 Sclerodactyly	0.571	0.429
L94.2 Calcinosis cutis	0.571	0.429
L94.1 Linear scleroderma	0.571	0.429
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.571	0.429
J70 Respiratory conditions due to other external agents	0.570	0.430
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours	0.570	0.430
J66 Airway disease due to specific organic dust	0.570	0.430
J63 Pneumoconiosis due to other inorganic dusts	0.570	0.430
J62 Pneumoconiosis due to dust containing silica	0.570	0.430
J65 Pneumoconiosis associated with tuberculosis	0.570	0.430
J64 Unspecified pneumoconiosis	0.570	0.430
J60 Coalworker's pneumoconiosis	0.570	0.430
M87.2 Osteonecrosis due to previous trauma	0.569	0.431
M90.8 Osteopathy in other diseases classified elsewhere	0.569	0.431
M90.6 Osteitis deformans in neoplastic disease	0.569	0.431

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations