TreeWAS – Variant ID: rs11209718

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons	0.190	0.810	0.000
J90 Pleural effusion, not elsewhere classified	0.136	0.864	0.000
J90-J94 Other diseases of pleura	0.068	0.932	0.000
J93 Pneumothorax	0.061	0.939	0.000
J92 Pleural plaque	0.057	0.943	0.000
J92.9 Pleural plaque without asbestos	0.055	0.945	0.000
J93.8 Other pneumothorax	0.050	0.950	0.000
J93.9 Pneumothorax, unspecified	0.050	0.950	0.000
J93.0 Spontaneous tension pneumothorax	0.048	0.952	0.000
J93.1 Other spontaneous pneumothorax	0.043	0.957	0.000
J91 Pleural effusion in conditions classified elsewhere	0.040	0.960	0.000
D37.4 Colon	0.000	0.962	0.038
D37.0 Lip, oral cavity and pharynx	0.000	0.964	0.036
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.000	0.965	0.035
J94 Other pleural conditions	0.031	0.969	0.000
D37.7 Other digestive organs	0.000	0.971	0.029
D37.3 Appendix	0.000	0.971	0.029
D37.5 Rectum	0.000	0.973	0.027
D37.6 Liver, gallbladder and bile ducts	0.000	0.974	0.026
D37.2 Small intestine	0.000	0.976	0.024
J94.0 Chylous effusion	0.022	0.978	0.000
J94.1 Fibrothorax	0.022	0.978	0.000
J94.9 Pleural condition, unspecified	0.022	0.978	0.000
I20.9 Angina pectoris, unspecified	0.021	0.979	0.000
J94.2 Haemothorax	0.019	0.980	0.000
R45.8 Other symptoms and signs involving emotional state	0.019	0.981	0.000
D37.9 Digestive organ, unspecified	0.000	0.981	0.018
D37.1 Stomach	0.000	0.982	0.018
I20 Angina pectoris	0.018	0.982	0.000
R00.2 Palpitations	0.017	0.983	0.000
I20.0 Unstable angina	0.016	0.984	0.000
I20.1 Angina pectoris with documented spasm	0.016	0.984	0.000
C90.0 Multiple myeloma	0.000	0.985	0.015
N41.1 Chronic prostatitis	0.015	0.985	0.000
R45 Symptoms and signs involving emotional state	0.014	0.986	0.000
R45.4 Irritability and anger	0.013	0.987	0.000
R45.0 Nervousness	0.012	0.988	0.000
C83.3 Large cell (diffuse)	0.012	0.988	0.000
S32.10 Fracture of sacrum (closed)	0.000	0.988	0.012
R00.8 Other and unspecified abnormalities of heart beat	0.012	0.988	0.000
R45.6 Physical violence	0.011	0.989	0.000
J94.8 Other specified pleural conditions	0.011	0.989	0.000
R45.5 Hostility	0.011	0.989	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.011	0.989	0.000
S32.1 Fracture of sacrum	0.000	0.989	0.011
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters	0.011	0.989	0.000
I25 Chronic ischaemic heart disease	0.011	0.989	0.000
R45.1 Restlessness and agitation	0.010	0.990	0.000
J92.0 Pleural plaque with presence of asbestos	0.010	0.990	0.000
R45.3 Demoralisation and apathy	0.010	0.990	0.000
S32 Fracture of lumbar spine and pelvis	0.000	0.990	0.010
C90 Multiple myeloma and malignant plasma cell neoplasms	0.000	0.990	0.010
I20-I25 Ischaemic heart diseases	0.010	0.990	0.000
R00 Abnormalities of heart beat	0.010	0.990	0.000
I25.5 Ischaemic cardiomyopathy	0.010	0.990	0.000
C16.9 Stomach, unspecified	0.010	0.990	0.000
S32.0 Fracture of lumbar vertebra	0.000	0.990	0.010
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.010	0.990	0.000
S32.5 Fracture of pubis	0.000	0.990	0.010
S32.00 Fracture of lumbar vertebra (closed)	0.000	0.990	0.010
S32.4 Fracture of acetabulum	0.000	0.990	0.010
G12.2 Motor neuron disease	0.009	0.991	0.000
Z92.2 Personal history of long-term (current) use of other medicaments	0.009	0.991	0.000
S32.50 Fracture of pubis (closed)	0.000	0.991	0.009
I25.3 Aneurysm of heart	0.009	0.991	0.000
I25.1 Atherosclerotic heart disease	0.009	0.991	0.000
S32.40 Fracture of acetabulum (closed)	0.000	0.991	0.009
C90.1 Plasma cell leukaemia	0.000	0.991	0.009
R45.2 Unhappiness	0.009	0.991	0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.009	0.991	0.000
W19.2 School, other institution and public administrative area	0.008	0.992	0.000
R45.7 State of emotional shock and stress, unspecified	0.008	0.992	0.000
I23 Certain current complications following acute myocardial infarction	0.008	0.992	0.000
C16.3 Pyloric antrum	0.008	0.992	0.000
C90.3 Solitary plasmacytoma	0.000	0.992	0.008
S32.11 Fracture of sacrum (open)	0.000	0.992	0.008
I25.8 Other forms of chronic ischaemic heart disease	0.008	0.992	0.000
C90.2 Plasmacytoma, extramedullary	0.000	0.992	0.008
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.000	0.992	0.008
S62.20 Fracture of first metacarpal bone (closed)	0.000	0.992	0.008
I25.6 Silent myocardial ischaemia	0.008	0.992	0.000
C16 Malignant neoplasm of stomach	0.008	0.992	0.000
I24 Other acute ischaemic heart diseases	0.008	0.992	0.000
S32.7 Multiple fractures of lumbar spine and pelvis	0.000	0.992	0.008
S32.2 Fracture of coccyx	0.000	0.992	0.008
N92.3 Ovulation bleeding	0.007	0.993	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.007	0.993	0.000
S32.01 Fracture of lumbar vertebra (open)	0.000	0.993	0.007
S32.3 Fracture of ilium	0.000	0.993	0.007
S32.51 Fracture of pubis (open)	0.000	0.993	0.007
S32.41 Fracture of acetabulum (open)	0.000	0.993	0.007
Y51 Drugs primarily affecting the autonomic nervous system	0.007	0.993	0.000
R47.8 Other and unspecified speech disturbances	0.000	0.993	0.007
I23.8 Other current complications following acute myocardial infarction	0.007	0.993	0.000
C16.4 Pylorus	0.007	0.993	0.000
C16.0 Cardia	0.006	0.993	0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.000	0.994	0.006
C16.8 Overlapping lesion of stomach	0.006	0.994	0.000
G12 Spinal muscular atrophy and related syndromes	0.006	0.994	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.006	0.994	0.000
C16.1 Fundus of stomach	0.006	0.994	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.006	0.994	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.006	0.994	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.006	0.994	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.006	0.994	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.006	0.994	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.006	0.994	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.006	0.994	0.000
R00.1 Bradycardia, unspecified	0.006	0.994	0.000
C16.6 Greater curvature of stomach, unspecified	0.006	0.994	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.006	0.994	0.000
I24.1 Dressler's syndrome	0.006	0.994	0.000
I25.2 Old myocardial infarction	0.006	0.994	0.000
S32.21 Fracture of coccyx (open)	0.000	0.994	0.006
S32.20 Fracture of coccyx (closed)	0.000	0.994	0.006
S32.71 Multiple fractures of lumbar spine and pelvis (open)	0.000	0.994	0.006
I22 Subsequent myocardial infarction	0.006	0.994	0.000
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.000	0.994	0.006
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.006	0.994	0.000
M47.2 Other spondylosis with radiculopathy	0.006	0.994	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.006	0.994	0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome	0.006	0.994	0.000
I24.8 Other forms of acute ischaemic heart disease	0.006	0.994	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.005	0.994	0.000
S32.31 Fracture of ilium (open)	0.000	0.995	0.005
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.005	0.995	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.005	0.995	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.005	0.995	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.005	0.995	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.005	0.995	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.005	0.995	0.000
Y51.0 Anticholinesterase agents	0.005	0.995	0.000
S72.00 Fracture of neck of femur (closed)	0.005	0.995	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.005	0.995	0.000
E83.4 Disorders of magnesium metabolism	0.005	0.995	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.005	0.995	0.000
S32.30 Fracture of ilium (closed)	0.000	0.995	0.005
I20.8 Other forms of angina pectoris	0.005	0.995	0.000
S32.81 Fracture of other and unspecified parts of lumbar spine and pelvis (open)	0.000	0.995	0.005
G12.9 Spinal muscular atrophy, unspecified	0.005	0.995	0.000
G12.8 Other spinal muscular atrophies and related syndromes	0.005	0.995	0.000
G12.1 Other inherited spinal muscular atrophy	0.005	0.995	0.000
G12.0 Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]	0.005	0.995	0.000
N41 Inflammatory diseases of prostate	0.005	0.995	0.000
C16.2 Body of stomach	0.004	0.996	0.000
M47.29 Other spondylosis with radiculopathy (Site unspecified)	0.004	0.996	0.000
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)	0.004	0.996	0.000
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)	0.004	0.996	0.000
M47.24 Other spondylosis with radiculopathy (Thoracic region)	0.004	0.996	0.000
M47.23 Other spondylosis with radiculopathy (Cervicothoracic region)	0.004	0.996	0.000
M47.21 Other spondylosis with radiculopathy (Occipito-atlanto-axial region)	0.004	0.996	0.000
Y48 Anaesthetics and therapeutic gases	0.004	0.996	0.000
Y48.3 Local anaesthetics	0.004	0.996	0.000
N41.0 Acute prostatitis	0.004	0.996	0.000
Y49.5 Other antipsychotics and neuroleptics	0.004	0.996	0.000
I31.3 Pericardial effusion (noninflammatory)	0.004	0.996	0.000
M47.20 Other spondylosis with radiculopathy (Multiple sites in spine)	0.004	0.996	0.000
I25.4 Coronary artery aneurysm	0.004	0.996	0.001
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)	0.004	0.996	0.000
X49.9 Unspecified place	0.000	0.996	0.004
Y49 Psychotropic drugs, not elsewhere classified	0.004	0.996	0.000
I35.1 Aortic (valve) insufficiency	0.004	0.996	0.000
O14.9 Preeclampsia, unspecified	0.000	0.996	0.004
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.004	0.996	0.000
O14.0 Moderate preeclampsia	0.000	0.996	0.004
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.004	0.996	0.000
Y42.5 Other oestrogens and progestogens	0.004	0.996	0.000
N18.0 End-stage renal disease	0.004	0.996	0.000
Y48.2 Other and unspecified general anaesthetics	0.004	0.996	0.000
N41.8 Other inflammatory diseases of prostate	0.004	0.996	0.000
Y48.4 Anaesthetic, unspecified	0.004	0.996	0.000
G11 Hereditary ataxia	0.004	0.996	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.000	0.996	0.004
Y47 Sedatives, hypnotics and antianxiety drugs	0.004	0.996	0.000
S32.80 Fracture of other and unspecified parts of lumbar spine and pelvis (closed)	0.000	0.996	0.003
E10.4 With neurological complications	0.004	0.996	0.000
Y47.1 Benzodiazepines	0.004	0.996	0.000
G11.9 Hereditary ataxia, unspecified	0.004	0.996	0.000
Y52 Agents primarily affecting the cardiovascular system	0.004	0.996	0.000
I42.0 Dilated cardiomyopathy	0.004	0.996	0.000
N41.3 Prostatocystitis	0.003	0.996	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.004	0.996	0.000
M54.49 Lumbago with sciatica (Site unspecified)	0.000	0.996	0.004
E10.5 With peripheral circulatory complications	0.004	0.996	0.000
S62.2 Fracture of first metacarpal bone	0.000	0.996	0.003
C16.5 Lesser curvature of stomach, unspecified	0.003	0.997	0.000
I22.8 Subsequent myocardial infarction of other sites	0.003	0.997	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.003	0.997	0.000
Y42.1 Thyroid hormones and substitutes	0.003	0.997	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.003	0.997	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.003	0.997	0.000
S72.0 Fracture of neck of femur	0.003	0.997	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.003	0.997	0.000
Y48.5 Therapeutic gases	0.003	0.997	0.000
Y48.1 Parenteral anaesthetics	0.003	0.997	0.000
Y48.0 Inhaled anaesthetics	0.003	0.997	0.000
N41.2 Abscess of prostate	0.003	0.997	0.000
Y58 Bacterial vaccines	0.003	0.997	0.000
S61.9 Open wound of wrist and hand, part unspecified	0.000	0.997	0.003
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.003	0.997	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.003	0.997	0.000
D45 Polycythaemia vera	0.000	0.997	0.003
Y49.0 Tricyclic and tetracyclic antidepressants	0.003	0.997	0.000
C17.0 Duodenum	0.003	0.997	0.000
Q39 Congenital malformations of oesophagus	0.003	0.997	0.000
M35.0 Sicca syndrome [Sjogren]	0.000	0.997	0.003
Q39.4 Oesophageal web	0.003	0.997	0.000
D46.9 Myelodysplastic syndrome, unspecified	0.000	0.997	0.003
Y49.9 Psychotropic drug, unspecified	0.003	0.997	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.003	0.997	0.000
Y49.7 Psychostimulants with abuse potential	0.003	0.997	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.003	0.997	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.003	0.997	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.003	0.997	0.000
Y49.2 Other and unspecified antidepressants	0.003	0.997	0.000
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere	0.003	0.997	0.000
Y59 Other and unspecified vaccines and biological substances	0.003	0.997	0.000
E10 Insulin-dependent diabetes mellitus	0.003	0.997	0.000
E10.7 With multiple complications	0.003	0.997	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.003	0.997	0.000
D46 Myelodysplastic syndromes	0.000	0.997	0.003
Q38-Q45 Other congenital malformations of the digestive system	0.003	0.997	0.000
G11.1 Early-onset cerebellar ataxia	0.003	0.997	0.000
E10.1 With ketoacidosis	0.003	0.997	0.000
O14.1 Severe preeclampsia	0.000	0.997	0.003
H10.9 Conjunctivitis, unspecified	0.000	0.997	0.003
G14 Postpolio syndrome	0.003	0.997	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.003	0.997	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.000	0.997	0.003
K56.7 Ileus, unspecified	0.003	0.997	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.003	0.997	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.003	0.997	0.000
Y42.4 Oral contraceptives	0.003	0.997	0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.003	0.997	0.000
H52.0 Hypermetropia	0.000	0.997	0.003
C01 Malignant neoplasm of base of tongue	0.003	0.997	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.003	0.997	0.000
Y58.0 BCG vaccine	0.003	0.997	0.000
Q40 Other congenital malformations of upper alimentary tract	0.003	0.997	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.003	0.997	0.000
H10.4 Chronic conjunctivitis	0.000	0.997	0.003
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.003	0.997	0.000
G10 Huntington's disease	0.003	0.997	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.003	0.997	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.003	0.997	0.000
G11.8 Other hereditary ataxias	0.003	0.997	0.000
G11.3 Cerebellar ataxia with defective DNA repair	0.003	0.997	0.000
G11.2 Late-onset cerebellar ataxia	0.003	0.997	0.000
G11.0 Congenital nonprogressive ataxia	0.003	0.997	0.000
Y52.7 Peripheral vasodilators	0.003	0.997	0.000
Z53 Persons encountering health services for specifie procedures, not carried out	0.003	0.997	0.000
O14.2 HELLP syndrome	0.000	0.997	0.003
Y42.9 Other and unspecified hormone antagonists	0.003	0.997	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.003	0.997	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.003	0.997	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.003	0.997	0.000
Y47.4 Bromine compounds	0.003	0.997	0.000
Y47.3 Paraldehyde	0.003	0.997	0.000
Y47.2 Chloral derivatives	0.003	0.997	0.000
Y47.0 Barbiturates, not elsewhere classified	0.003	0.997	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.003	0.997	0.000
D46.2 Refractory anaemia with excess of blasts	0.000	0.997	0.003
I21.9 Acute myocardial infarction, unspecified	0.003	0.997	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.003	0.997	0.000
Q40.8 Other specified congenital malformations of upper alimentary tract	0.003	0.997	0.000
M96.8 Other postprocedural musculoskeletal disorders	0.003	0.997	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.003	0.997	0.000
E10.2 With renal complications	0.003	0.997	0.000
Y45.2 Propionic acid derivatives	0.003	0.997	0.000
C83.6 Undifferentiated (diffuse)	0.003	0.997	0.000
C83.5 Lymphoblastic (diffuse)	0.003	0.997	0.000
C83.4 Immunoblastic (diffuse)	0.003	0.997	0.000
C83.2 Mixed small and large cell (diffuse)	0.003	0.997	0.000
Y59.0 Viral vaccines	0.003	0.997	0.000
S72.30 Fracture of shaft of femur (closed)	0.003	0.997	0.000
Q39.6 Diverticulum of oesophagus	0.003	0.997	0.000
S62.21 Fracture of first metacarpal bone (open)	0.000	0.997	0.003
G11.4 Hereditary spastic paraplegia	0.003	0.997	0.000
E10.8 With unspecified complications	0.003	0.997	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.003	0.997	0.000
Y56.9 Topical agent, unspecified	0.003	0.997	0.000
Y56.8 Other topical agents	0.003	0.997	0.000
Y56.7 Dental drugs, topically applied	0.003	0.997	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.003	0.997	0.000
Y56.5 Ophthalmological drugs and preparations	0.003	0.997	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.003	0.997	0.000
Y56.2 Local astringents and local detergents	0.003	0.997	0.000
Y56.1 Antipruritics	0.003	0.997	0.000
Q45 Other congenital malformations of digestive system	0.003	0.997	0.000
S72.01 Fracture of neck of femur (open)	0.003	0.997	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.003	0.997	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.003	0.997	0.000
G13.0 Paraneoplastic neuromyopathy and neuropathy	0.003	0.997	0.000
Q38.0 Congenital malformations of lips, not elsewhere classified	0.003	0.997	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.003	0.997	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.000	0.997	0.003
D46.7 Other myelodysplastic syndromes	0.000	0.997	0.003
Y58.9 Other and unspecified bacterial vaccines	0.003	0.997	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.003	0.997	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.003	0.997	0.000
Y58.5 Diphtheria vaccine	0.003	0.997	0.000
Y58.4 Tetanus vaccine	0.003	0.997	0.000
Y58.3 Plague vaccine	0.003	0.997	0.000
Y58.2 Cholera vaccine	0.003	0.997	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.003	0.997	0.000
C83.1 Small cleaved cell (diffuse)	0.003	0.997	0.000
Q40.1 Congenital hiatus hernia	0.003	0.997	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.003	0.997	0.000
Q39.9 Congenital malformation of oesophagus, unspecified	0.003	0.997	0.000
C83.0 Small cell (diffuse)	0.003	0.997	0.000
I63.8 Other cerebral infarction	0.003	0.997	0.000
Q39.8 Other congenital malformations of oesophagus	0.002	0.997	0.000
Q39.5 Congenital dilatation of oesophagus	0.002	0.997	0.000
Q39.3 Congenital stenosis and stricture of oesophagus	0.002	0.997	0.000
Q39.2 Congenital tracheooesophageal fistula without atresia	0.002	0.997	0.000
Q39.1 Atresia of oesophagus with tracheooesophageal fistula	0.002	0.997	0.000
Q39.0 Atresia of oesophagus without fistula	0.002	0.997	0.000
Q44.6 Cystic disease of liver	0.003	0.997	0.000
Y44 Agents primarily affecting blood constituents	0.002	0.997	0.000
G13.8 Systemic atrophy primarily affecting central nervous system in other diseases classified elsewhere	0.002	0.997	0.000
G13.2 Systemic atrophy primarily affecting central nervous system in myxoedema	0.002	0.997	0.000
G13.1 Other systemic atrophy primarily affecting central nervous system in neoplastic disease	0.002	0.997	0.000
Y45.0 Opioids and related analgesics	0.003	0.997	0.000
Y59.9 Vaccine or biological substance, unspecified	0.002	0.997	0.000
Y59.8 Other specified vaccines and biological substances	0.002	0.997	0.000
Y59.2 Protozoal vaccines	0.002	0.997	0.000
Y59.1 Rickettsial vaccines	0.002	0.997	0.000
Q38.7 Pharyngeal pouch	0.003	0.997	0.000
Y42.2 Antithyroid drugs	0.002	0.997	0.000
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.000	0.997	0.002
D46.5 Refractory anaemia with multi-lineage dysplasia	0.000	0.997	0.002
D46.3 Refractory anaemia with excess of blasts with transformation	0.000	0.997	0.002
D46.0 Refractory anaemia without sideroblasts, so stated	0.000	0.997	0.002
Q24.8 Other specified congenital malformations of heart	0.003	0.997	0.000
E10.0 With coma	0.002	0.997	0.000
Q38.5 Congenital malformations of palate, not elsewhere classified	0.002	0.997	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.002	0.997	0.000
Y56.3 Emollients, demulcents and protectants	0.002	0.997	0.000
J80 Adult respiratory distress syndrome	0.000	0.997	0.003
Q42 Congenital absence, atresia and stenosis of large intestine	0.002	0.997	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.002	0.997	0.000
C02.1 Border of tongue	0.002	0.997	0.000
D46.1 Refractory anaemia with sideroblasts	0.000	0.997	0.002
Q44.7 Other congenital malformations of liver	0.002	0.997	0.000
Y41.5 Antiviral drugs	0.002	0.997	0.000
Y50.9 Central nervous system stimulant, unspecified	0.002	0.997	0.000
Y50.8 Other central nervous system stimulants	0.002	0.997	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.002	0.997	0.000
Y50.1 Opioid receptor antagonists	0.002	0.997	0.000
Y50.0 Analeptics	0.002	0.997	0.000
Q38.6 Other congenital malformations of mouth	0.002	0.998	0.000
Q45.3 Other congenital malformations of pancreas and pancreatic duct	0.002	0.998	0.000
S72.3 Fracture of shaft of femur	0.002	0.998	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.002	0.998	0.000
Y53.7 Emetics	0.002	0.998	0.000
Y53.6 Antidiarrhoeal drugs	0.002	0.998	0.000
Y53.5 Digestants	0.002	0.998	0.000
Y53.3 Saline and osmotic laxatives	0.002	0.998	0.000
Y53.2 Stimulant laxatives	0.002	0.998	0.000
Y53.0 Histamine H2-receptor antagonists	0.002	0.998	0.000
C07 Malignant neoplasm of parotid gland	0.002	0.998	0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.000	0.998	0.002
Y46 Antiepileptics and anti-Parkinsonism drugs	0.002	0.998	0.000
E27.8 Other specified disorders of adrenal gland	0.002	0.998	0.000
Q40.2 Other specified congenital malformations of stomach	0.002	0.998	0.000
O03.9 Complete or unspecified, without complication	0.000	0.998	0.002
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.002	0.998	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.002	0.998	0.000
Q44.5 Other congenital malformations of bile ducts	0.002	0.998	0.000
Y59.3 Immunoglobulin	0.002	0.998	0.000
H10 Conjunctivitis	0.000	0.998	0.002
M10.96 Gout, unspecified (Lower leg)	0.002	0.998	0.000
C83.7 Burkitt's tumour	0.002	0.998	0.000
Y52.1 Calcium-channel blockers	0.002	0.998	0.000
Q38.8 Other congenital malformations of pharynx	0.002	0.998	0.000
Q38.4 Congenital malformations of salivary glands and ducts	0.002	0.998	0.000
Q38.3 Other congenital malformations of tongue	0.002	0.998	0.000
Q38.2 Macroglossia	0.002	0.998	0.000
Y53.4 Other laxatives	0.002	0.998	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.002	0.998	0.000
Y55.5 Anticommon cold drugs	0.002	0.998	0.000
Y55.4 Expectorants	0.002	0.998	0.000
Y55.3 Antitussives	0.002	0.998	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.002	0.998	0.000
Y55.0 Oxytocic drugs	0.002	0.998	0.000
M47.99 Spondylosis, unspecified (Site unspecified)	0.002	0.998	0.000
Q44.3 Congenital stenosis and stricture of bile ducts	0.002	0.998	0.000
Q44.2 Atresia of bile ducts	0.002	0.998	0.000
Q44.1 Other congenital malformations of gallbladder	0.002	0.998	0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.002	0.998	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.002	0.998	0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters	0.002	0.998	0.000
J86.9 Pyothorax without fistula	0.002	0.998	0.000
O03.4 Incomplete, without complication	0.000	0.998	0.002
Q43 Other congenital malformations of intestine	0.002	0.998	0.000
Q44.4 Choledochal cyst	0.002	0.998	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.002	0.998	0.000
Z94.0 Kidney transplant status	0.002	0.998	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.002	0.998	0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
K72.9 Hepatic failure, unspecified	0.000	0.998	0.002
C12 Malignant neoplasm of pyriform sinus	0.002	0.998	0.000
S72.31 Fracture of shaft of femur (open)	0.002	0.998	0.000
Q45.9 Congenital malformation of digestive system, unspecified	0.002	0.998	0.000
Q45.8 Other specified congenital malformations of digestive system	0.002	0.998	0.000
Q45.2 Congenital pancreatic cyst	0.002	0.998	0.000
Q45.1 Annular pancreas	0.002	0.998	0.000
Q45.0 Agenesis, aplasia and hypoplasia of pancreas	0.002	0.998	0.000
Q40.3 Congenital malformation of stomach, unspecified	0.002	0.998	0.000
Y41.0 Sulphonamides	0.002	0.998	0.000
Y45.8 Other analgesics and antipyretics	0.002	0.998	0.000
Y45.4 Antirheumatics	0.002	0.998	0.000
C05 Malignant neoplasm of palate	0.002	0.998	0.000
C03 Malignant neoplasm of gum	0.002	0.998	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.002	0.998	0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.002	0.998	0.000
Y41.4 Anthelminthics	0.002	0.998	0.000
Y41.3 Other antiprotozoal drugs	0.002	0.998	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.002	0.998	0.000
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure	0.002	0.998	0.000
C05.9 Palate, unspecified	0.002	0.998	0.000
C03.1 Lower gum	0.002	0.998	0.000
D75.1 Secondary polycythaemia	0.000	0.998	0.002
F22.0 Delusional disorder	0.002	0.998	0.000
Q43.9 Congenital malformation of intestine, unspecified	0.002	0.998	0.000
E10.6 With other specified complications	0.002	0.998	0.000
Q38.1 Ankyloglossia	0.002	0.998	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.002	0.998	0.000
Y44.7 Plasma substitutes	0.002	0.998	0.000
Y44.6 Natural blood and blood products	0.002	0.998	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.002	0.998	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.002	0.998	0.000
Y45.5 4-Aminophenol derivatives	0.002	0.998	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.000	0.998	0.002
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.002	0.998	0.000
Q41.9 Congenital absence, atresia and stenosis of small intestine, part unspecified	0.002	0.998	0.000
Q41.8 Congenital absence, atresia and stenosis of other specified parts of small intestine	0.002	0.998	0.000
Q41.2 Congenital absence, atresia and stenosis of ileum	0.002	0.998	0.000
Q41.1 Congenital absence, atresia and stenosis of jejunum	0.002	0.998	0.000
Q41.0 Congenital absence, atresia and stenosis of duodenum	0.002	0.998	0.000
Q42.9 Congenital absence, atresia and stenosis of large intestine, part unspecified	0.002	0.998	0.000
Q42.8 Congenital absence, atresia and stenosis of other parts of large intestine	0.002	0.998	0.000
Q42.3 Congenital absence, atresia and stenosis of anus without fistula	0.002	0.998	0.000
Q42.2 Congenital absence, atresia and stenosis of anus with fistula	0.002	0.998	0.000
Q42.1 Congenital absence, atresia and stenosis of rectum without fistula	0.002	0.998	0.000
Q42.0 Congenital absence, atresia and stenosis of rectum with fistula	0.002	0.998	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.002	0.998	0.000
Y46.5 Valproic acid	0.002	0.998	0.000
Z01.7 Laboratory examination	0.002	0.998	0.000
D42.9 Meninges, unspecified	0.000	0.998	0.002
D42.1 Spinal meninges	0.000	0.998	0.002
D42.0 Cerebral meninges	0.000	0.998	0.002
D46.4 Refractory anaemia, unspecified	0.000	0.998	0.002
E28.2 Polycystic ovarian syndrome	0.002	0.998	0.000
Y46.8 Antispasticity drugs	0.002	0.998	0.000
Y46.3 Deoxybarbiturates	0.002	0.998	0.000
Y46.1 Oxazolidinediones	0.002	0.998	0.000
Y46.0 Succinimides	0.002	0.998	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.000	0.998	0.002
S82.70 Multiple fractures of lower leg (closed)	0.002	0.998	0.000
Y46.6 Other and unspecified antiepileptics	0.002	0.998	0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.002	0.998	0.000
H10.8 Other conjunctivitis	0.000	0.998	0.002
H10.5 Blepharoconjunctivitis	0.000	0.998	0.002
H10.3 Acute conjunctivitis, unspecified	0.000	0.998	0.002
H10.2 Other acute conjunctivitis	0.000	0.998	0.002
M96.1 Postlaminectomy syndrome, not elsewhere classified	0.002	0.998	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.002	0.998	0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.000	0.998	0.002
Q43.1 Hirschsprung's disease	0.002	0.998	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.002	0.998	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.000	0.998	0.002
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.000	0.998	0.002
C05.0 Hard palate	0.002	0.998	0.000
H10.1 Acute atopic conjunctivitis	0.000	0.998	0.002
Y41.1 Antimycobacterial drugs	0.002	0.998	0.000
Y46.7 Anti-Parkinsonism drugs	0.002	0.998	0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.002	0.998	0.000
F22 Persistent delusional disorders	0.002	0.998	0.000
S72 Fracture of femur	0.002	0.998	0.000
C03.9 Gum, unspecified	0.002	0.998	0.000
F20.0 Paranoid schizophrenia	0.002	0.998	0.000
Q43.7 Persistent cloaca	0.002	0.998	0.000
Q43.6 Congenital fistula of rectum and anus	0.002	0.998	0.000
Q43.5 Ectopic anus	0.002	0.998	0.000
Q43.4 Duplication of intestine	0.002	0.998	0.000
Q43.2 Other congenital functional disorders of colon	0.002	0.998	0.000
Q43.0 Meckel's diverticulum	0.002	0.998	0.000
Q60.2 Renal agenesis, unspecified	0.002	0.998	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.002	0.998	0.000
Q24 Other congenital malformations of heart	0.002	0.998	0.000
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances	0.000	0.998	0.002
F20.5 Residual schizophrenia	0.002	0.998	0.000
Q43.3 Congenital malformations of intestinal fixation	0.002	0.998	0.000
Q79.6 Ehlers-Danlos syndrome	0.002	0.998	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.998	0.002
B35.3 Tinea pedis	0.000	0.998	0.002
D44.8 Pluriglandular involvement	0.000	0.998	0.002
E27.4 Other and unspecified adrenocortical insufficiency	0.002	0.998	0.000
H10.0 Mucopurulent conjunctivitis	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations