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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs112242463
log Bayes Factor = 13.4022
Chromosome 2   position 45,808,479  (GRCh37) Explore rs112242463 on Ensembl!
Variant rs112242463 is part of Cluster X0070

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.999 0.001 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.997 0.003 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.995 0.005 0.000
Chapter XI Diseases of the digestive system
0.993 0.007 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.993 0.007 0.000
Chapter XX External causes of morbidity and mortality
0.993 0.007 0.000
M50-M54 Other dorsopathies
0.992 0.008 0.000
K80 Cholelithiasis
0.992 0.008 0.000
M54 Dorsalgia
0.991 0.009 0.000
Chapter X Diseases of the respiratory system
0.990 0.010 0.000
M54.5 Low back pain
0.988 0.012 0.000
K80.1 Calculus of gallbladder with other cholecystitis
0.986 0.014 0.000
Chapter XIV Diseases of the genitourinary system
0.985 0.015 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.985 0.015 0.000
N30-N39 Other diseases of urinary system
0.982 0.018 0.000
O80-O84 Delivery
0.975 0.025 0.000
E70-E90 Metabolic disorders
0.973 0.027 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.972 0.028 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.967 0.033 0.000
J09-J18 Influenza and pneumonia
0.965 0.035 0.000
O80 Single spontaneous delivery
0.959 0.041 0.000
N35 Urethral stricture
0.959 0.041 0.000
Y95 Nosocomial condition
0.957 0.043 0.000
K80.2 Calculus of gallbladder without cholecystitis
0.945 0.055 0.000
M54.56 Low back pain (Lumbar region)
0.945 0.055 0.000
K82 Other diseases of gallbladder
0.944 0.056 0.000
N39 Other disorders of urinary system
0.943 0.057 0.000
E65-E68 Obesity and other hyperalimentation
0.942 0.058 0.000
O80.0 Spontaneous vertex delivery
0.938 0.062 0.000
K70-K77 Diseases of liver
0.938 0.062 0.000
N39.0 Urinary tract infection, site not specified
0.937 0.063 0.000
N35.9 Urethral stricture, unspecified
0.933 0.067 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.930 0.070 0.000
Chapter VII Diseases of the eye and adnexa
0.930 0.070 0.000
Chapter II Neoplasms
0.926 0.074 0.000
O60-O75 Complications of labour and delivery
0.924 0.076 0.000
D50-D53 Nutritional anaemias
0.923 0.077 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.922 0.078 0.000
M54.59 Low back pain (Site unspecified)
0.922 0.078 0.000
J18 Pneumonia, organism unspecified
0.921 0.079 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.909 0.091 0.000
Chapter I Certain infectious and parasitic diseases
0.904 0.096 0.000
E66 Obesity
0.902 0.098 0.000
S20-S29 Injuries to the thorax
0.902 0.098 0.000
N30 Cystitis
0.901 0.099 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.899 0.101 0.000
E87.2 Acidosis
0.895 0.105 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.894 0.106 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.889 0.111 0.000
D50 Iron deficiency anaemia
0.884 0.116 0.000
K81 Cholecystitis
0.878 0.122 0.000
K82.8 Other specified diseases of gallbladder
0.877 0.123 0.000
C79 Secondary malignant neoplasm of other sites
0.876 0.124 0.000
E66.9 Obesity, unspecified
0.876 0.124 0.000
E20-E35 Disorders of other endocrine glands
0.875 0.125 0.000
O00-O08 Pregnancy with abortive outcome
0.871 0.129 0.000
B95-B98 Bacterial, viral and other infectious agents
0.870 0.130 0.000
E00-E07 Disorders of thyroid gland
0.866 0.134 0.000
M54.57 Low back pain (Lumbosacral region)
0.865 0.135 0.000
M54.2 Cervicalgia
0.864 0.136 0.000
J90-J94 Other diseases of pleura
0.861 0.139 0.000
J40-J47 Chronic lower respiratory diseases
0.858 0.142 0.000
J18.1 Lobar pneumonia, unspecified
0.858 0.142 0.000
K72 Hepatic failure, not elsewhere classified
0.857 0.143 0.000
Chapter XXII Codes for special purposes
0.855 0.145 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.853 0.147 0.000
S40-S49 Injuries to the shoulder and upper arm
0.853 0.147 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.852 0.148 0.000
E87.0 Hyperosmolality and hypernatraemia
0.845 0.155 0.000
K85 Acute pancreatitis
0.843 0.157 0.000
D50.8 Other iron deficiency anaemias
0.842 0.158 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.840 0.160 0.000
S00-S09 Injuries to the head
0.838 0.162 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.837 0.163 0.000
K76 Other diseases of liver
0.837 0.163 0.000
D80-D89 Certain disorders involving the immune mechanism
0.836 0.164 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.836 0.164 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.834 0.166 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.832 0.168 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.826 0.174 0.000
M50 Cervical disk disorders
0.826 0.174 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.823 0.177 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.823 0.177 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.822 0.178 0.000
N30.9 Cystitis, unspecified
0.822 0.178 0.000
O80.9 Single spontaneous delivery, unspecified
0.821 0.179 0.000
S10-S19 Injuries to the neck
0.819 0.181 0.000
M51 Other intervertebral disk disorders
0.817 0.183 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.814 0.186 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.814 0.186 0.000
E87.6 Hypokalaemia
0.809 0.191 0.000
O02 Other abnormal products of conception
0.808 0.192 0.000
E10-E14 Diabetes mellitus
0.807 0.193 0.000
J44 Other chronic obstructive pulmonary disease
0.807 0.193 0.000
M54.55 Low back pain (Thoracolumbar region)
0.804 0.196 0.000
K82.4 Cholesterolosis of gallbladder
0.802 0.198 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.801 0.199 0.000
N30.8 Other cystitis
0.800 0.200 0.000
H53-H54 Visual disturbances and blindness
0.799 0.201 0.000
K81.0 Acute cholecystitis
0.797 0.203 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.796 0.204 0.000
N35.8 Other urethral stricture
0.791 0.209 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.790 0.209 0.000
O26.8 Other specified pregnancy-related conditions
0.790 0.210 0.000
Chapter IX Diseases of the circulatory system
0.789 0.211 0.000
D69 Purpura and other haemorrhagic conditions
0.781 0.219 0.000
T81 Complications of procedures, not elsewhere classified
0.776 0.224 0.000
C60-C63 Malignant neoplasms of male genital organs
0.776 0.224 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.775 0.225 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.774 0.226 0.000
M54.22 Cervicalgia (Cervical region)
0.774 0.226 0.000
H52 Disorders of refraction and accommodation
0.773 0.227 0.000
N17-N19 Renal failure
0.773 0.227 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.772 0.228 0.000
K72.9 Hepatic failure, unspecified
0.771 0.229 0.000
Y00-Y09 Assault
0.770 0.230 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.769 0.231 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.769 0.231 0.000
J90 Pleural effusion, not elsewhere classified
0.768 0.232 0.000
J18.0 Bronchopneumonia, unspecified
0.766 0.234 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.765 0.235 0.000
K80.4 Calculus of bile duct with cholecystitis
0.762 0.238 0.000
M54.6 Pain in thoracic spine
0.761 0.239 0.000
S50-S59 Injuries to the elbow and forearm
0.761 0.239 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.761 0.239 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.760 0.240 0.000
V10-V19 Pedal cyclist injured in transport accident
0.758 0.242 0.000
O61 Failed induction of labour
0.758 0.242 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.757 0.242 0.000
O85-O92 Complications predominantly related to the puerperium
0.757 0.243 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.756 0.244 0.000
S27 Injury of other and unspecified intrathoracic organs
0.755 0.245 0.000
O02.1 Missed abortion
0.755 0.245 0.000
M60-M63 Disorders of muscles
0.754 0.246 0.000
N60-N64 Disorders of breast
0.754 0.246 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.753 0.246 0.000
M54.4 Lumbago with sciatica
0.753 0.247 0.000
Chapter VIII Diseases of the ear and mastoid process
0.750 0.250 0.000
J60-J70 Lung diseases due to external agents
0.750 0.250 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.749 0.251 0.000
T86 Failure and rejection of transplanted organs and tissues
0.748 0.252 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.748 0.252 0.000
S70-S79 Injuries to the hip and thigh
0.746 0.253 0.000
N40-N51 Diseases of male genital organs
0.746 0.254 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.745 0.255 0.000
D50.9 Iron deficiency anaemia, unspecified
0.742 0.258 0.000
W00-W19 Falls
0.742 0.258 0.000
D60-D64 Aplastic and other anaemias
0.740 0.259 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.740 0.260 0.000
J14 Pneumonia due to Haemophilus influenzae
0.740 0.260 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.740 0.260 0.000
T92 Sequelae of injuries of upper limb
0.740 0.260 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.739 0.261 0.000
M86-M90 Other osteopathies
0.739 0.261 0.000
K11 Diseases of salivary glands
0.738 0.262 0.000
H54 Blindness and low vision
0.736 0.264 0.000
M65-M68 Disorders of synovium and tendon
0.735 0.265 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.735 0.265 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.734 0.266 0.000
E86 Volume depletion
0.732 0.268 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.731 0.269 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.729 0.270 0.000
N00-N08 Glomerular diseases
0.729 0.271 0.000
M91-M94 Chondropathies
0.729 0.271 0.000
K86 Other diseases of pancreas
0.728 0.272 0.000
N50 Other disorders of male genital organs
0.728 0.272 0.000
D68 Other coagulation defects
0.728 0.272 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.727 0.273 0.000
H55-H59 Other disorders of eye and adnexa
0.724 0.276 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.723 0.277 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.723 0.277 0.000
H52.1 Myopia
0.722 0.278 0.000
J10 Influenza due to identified influenza virus
0.722 0.278 0.000
O66 Other obstructed labour
0.722 0.278 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.721 0.279 0.000
I30-I52 Other forms of heart disease
0.721 0.279 0.000
J43 Emphysema
0.721 0.279 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.720 0.280 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.720 0.280 0.000
Y52 Agents primarily affecting the cardiovascular system
0.719 0.281 0.000
S80-S89 Injuries to the knee and lower leg
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M40-M43 Deforming dorsopathies
0.716 0.284 0.000
T33-T35 Frostbite
0.715 0.285 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.715 0.285 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.715 0.285 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.715 0.285 0.000
T00-T07 Injuries involving multiple body regions
0.715 0.285 0.000
S90-S99 Injuries to the ankle and foot
0.715 0.285 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.713 0.287 0.000
M51.2 Other specified intervertebral disk displacement
0.713 0.287 0.000
E87.7 Fluid overload
0.712 0.287 0.000
Chapter V Mental and behavioural disorders
0.712 0.288 0.000
M00-M03 Infectious arthropathies
0.712 0.288 0.000
K85.9 Acute pancreatitis, unspecified
0.712 0.288 0.000
Y35-Y36 Legal intervention and operations of war
0.712 0.288 0.000
Y10-Y34 Event of undetermined intent
0.712 0.288 0.000
X85-X99 Assault
0.712 0.288 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.712 0.288 0.000
X50-X57 Overexertion, travel and privation
0.712 0.288 0.000
X30-X39 Exposure to forces of nature
0.712 0.288 0.000
X20-X29 Contact with venomous animals and plants
0.712 0.288 0.000
X10-X19 Contact with heat and hot substances
0.712 0.288 0.000
X00-X09 Exposure to smoke, fire and flames
0.712 0.288 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.712 0.288 0.000
W75-W84 Other accidental threats to breathing
0.712 0.288 0.000
W65-W74 Accidental drowning and submersion
0.712 0.288 0.000
W50-W64 Exposure to animate mechanical forces
0.712 0.288 0.000
V98-V99 Other and unspecified transport accidents
0.712 0.288 0.000
V95-V97 Air and space transport accidents
0.712 0.288 0.000
V90-V94 Water transport accidents
0.712 0.288 0.000
V80-V89 Other land transport accidents
0.712 0.288 0.000
V70-V79 Bus occupant injured in transport accident
0.712 0.288 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.712 0.288 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.712 0.288 0.000
V40-V49 Car occupant injured in transport accident
0.712 0.288 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.712 0.288 0.000
V01-V09 Pedestrian injured in transport accident
0.712 0.288 0.000
D69.6 Thrombocytopenia, unspecified
0.712 0.288 0.000
M53 Other dorsopathies, not elsewhere classified
0.711 0.288 0.000
K80.3 Calculus of bile duct with cholangitis
0.711 0.289 0.000
K80.8 Other cholelithiasis
0.711 0.289 0.000
E40-E46 Malnutrition
0.710 0.290 0.000
M54.8 Other dorsalgia
0.710 0.290 0.000
M54.0 Panniculitis affecting regions of neck and back
0.710 0.290 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.710 0.290 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.709 0.291 0.000
V20-V29 Motorcycle rider injured in transport accident
0.709 0.291 0.000
E27 Other disorders of adrenal gland
0.709 0.291 0.000
M54.54 Low back pain-Thoracic
0.708 0.291 0.000
M54.53 Low back pain-Cervicothoracic
0.708 0.291 0.000
M54.52 Low back pain-Cervical
0.708 0.291 0.000
M54.51 Low back pain-Occipit-atl-axl
0.708 0.291 0.000
M54.50 Low back pain (Multiple sites in spine)
0.708 0.291 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.708 0.292 0.000
J81 Pulmonary oedema
0.708 0.292 0.000
D55-D59 Haemolytic anaemias
0.706 0.294 0.000
C77.9 Lymph node, unspecified
0.706 0.294 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.705 0.295 0.000
O23 Infections of genito-urinary tract in pregnancy
0.704 0.296 0.000
N37 Urethral disorders in diseases classified elsewhere
0.704 0.296 0.000
N34 Urethritis and urethral syndrome
0.704 0.296 0.000
N33 Bladder disorders in diseases classified elsewhere
0.704 0.296 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.704 0.296 0.000
M50.2 Other cervical disk displacement
0.704 0.296 0.000
A30-A49 Other bacterial diseases
0.704 0.296 0.000
J18.9 Pneumonia, unspecified
0.703 0.297 0.000
C51-C58 Malignant neoplasms of female genital organs
0.701 0.299 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.701 0.299 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.701 0.299 0.000
N50.1 Vascular disorders of male genital organs
0.700 0.300 0.000
T91 Sequelae of injuries of neck and trunk
0.700 0.300 0.000
K12 Stomatitis and related lesions
0.700 0.300 0.000
O84 Multiple delivery
0.699 0.301 0.000
O83 Other assisted single delivery
0.699 0.301 0.000
O81 Single delivery by forceps and vacuum extractor
0.699 0.301 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.699 0.301 0.000
I35 Nonrheumatic aortic valve disorders
0.698 0.302 0.000
E85 Amyloidosis
0.698 0.302 0.000
E84 Cystic fibrosis
0.698 0.302 0.000
E79 Disorders of purine and pyrimidine metabolism
0.698 0.302 0.000
E77 Disorders of glycoprotein metabolism
0.698 0.302 0.000
E76 Disorders of glycosaminoglycan metabolism
0.698 0.302 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.698 0.302 0.000
E74 Other disorders of carbohydrate metabolism
0.698 0.302 0.000
E73 Lactose intolerance
0.698 0.302 0.000
E72 Other disorders of amino-acid metabolism
0.698 0.302 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.698 0.302 0.000
E70 Disorders of aromatic amino-acid metabolism
0.698 0.302 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.698 0.302 0.000
T79-T79 Certain early complications of trauma
0.697 0.302 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.697 0.303 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.697 0.303 0.000
Y98 Lifestyle-related condition
0.697 0.303 0.000
Y97 Environmental-pollution-related condition
0.697 0.303 0.000
Y96 Work-related condition
0.697 0.303 0.000
N39.8 Other specified disorders of urinary system
0.697 0.303 0.000
K72.0 Acute and subacute hepatic failure
0.696 0.304 0.000
T90 Sequelae of injuries of head
0.696 0.304 0.000
E11 Non-insulin-dependent diabetes mellitus
0.695 0.305 0.000
D84 Other immunodeficiencies
0.694 0.306 0.000
E88 Other metabolic disorders
0.693 0.307 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.693 0.307 0.000
E87.4 Mixed disorder of acid-base balance
0.693 0.307 0.000
E87.3 Alkalosis
0.693 0.307 0.000
H10-H13 Disorders of conjunctiva
0.692 0.307 0.000
O63 Long labour
0.692 0.308 0.000
J17 Pneumonia in diseases classified elsewhere
0.692 0.308 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.692 0.308 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.692 0.308 0.000
J12 Viral pneumonia, not elsewhere classified
0.692 0.308 0.000
J11 Influenza, virus not identified
0.692 0.308 0.000
J09 Influenza due to certain identified influenza virus
0.692 0.308 0.000
S00 Superficial injury of head
0.692 0.308 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.692 0.308 0.000
M54.3 Sciatica
0.691 0.309 0.000
S02 Fracture of skull and facial bones
0.690 0.310 0.000
M45-M49 Spondylopathies
0.690 0.310 0.000
T93 Sequelae of injuries of lower limb
0.689 0.310 0.000
O48 Prolonged pregnancy
0.689 0.311 0.000
N10-N16 Renal tubulo-interstitial diseases
0.689 0.311 0.000
O73 Retained placenta and membranes, without haemorrhage
0.689 0.311 0.000
S06 Intracranial injury
0.688 0.312 0.000
O80.8 Other single spontaneous delivery
0.688 0.312 0.000
O80.1 Spontaneous breech delivery
0.688 0.312 0.000
N35.1 Postinfective urethral stricture, not elsewhere classified
0.688 0.312 0.000
N35.0 Posttraumatic urethral stricture
0.688 0.312 0.000
K81.9 Cholecystitis, unspecified
0.688 0.312 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.687 0.313 0.000
S60-S69 Injuries to the wrist and hand
0.687 0.313 0.000
S40 Superficial injury of shoulder and upper arm
0.685 0.315 0.000
N30.0 Acute cystitis
0.685 0.315 0.000
K65-K67 Diseases of peritoneum
0.684 0.316 0.000
K76.8 Other specified diseases of liver
0.684 0.316 0.000
S19 Other and unspecified injuries of neck
0.684 0.316 0.000
H50 Other strabismus
0.683 0.316 0.000
K09 Cysts of oral region, not elsewhere classified
0.683 0.317 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.683 0.317 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.683 0.317 0.000
C77.0 Lymph nodes of head, face and neck
0.682 0.318 0.000
K74 Fibrosis and cirrhosis of liver
0.682 0.318 0.000
E28 Ovarian dysfunction
0.681 0.319 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.680 0.320 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.679 0.321 0.000
Y84.6 Urinary catheterisation
0.679 0.321 0.000
B35-B49 Mycoses
0.679 0.321 0.000
T66-T78 Other and unspecified effects of external causes
0.679 0.321 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.679 0.321 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.678 0.322 0.000
N99-N99 Other disorders of the genitourinary system
0.677 0.323 0.000
K82.9 Disease of gallbladder, unspecified
0.677 0.323 0.000
K82.3 Fistula of gallbladder
0.677 0.323 0.000
K82.2 Perforation of gallbladder
0.677 0.323 0.000
K82.1 Hydrops of gallbladder
0.677 0.323 0.000
K82.0 Obstruction of gallbladder
0.677 0.323 0.000
N39.2 Orthostatic proteinuria, unspecified
0.676 0.324 0.000
N39.1 Persistent proteinuria, unspecified
0.676 0.324 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.676 0.324 0.000
E67 Other hyperalimentation
0.675 0.324 0.000
E68 Sequelae of hyperalimentation
0.675 0.324 0.000
E65 Localised adiposity
0.675 0.324 0.000
E03 Other hypothyroidism
0.675 0.325 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.675 0.325 0.000
C77.3 Axillary and upper limb lymph nodes
0.673 0.327 0.000
K77 Liver disorders in diseases classified elsewhere
0.672 0.328 0.000
K73 Chronic hepatitis, not elsewhere classified
0.672 0.328 0.000
K71 Toxic liver disease
0.672 0.328 0.000
K04 Diseases of pulp and periapical tissues
0.671 0.329 0.000
J95-J99 Other diseases of the respiratory system
0.670 0.329 0.000
H54.0 Blindness, both eyes
0.670 0.330 0.000
A80-A89 Viral infections of the central nervous system
0.670 0.330 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.668 0.332 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.668 0.332 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.668 0.332 0.000
J46 Status asthmaticus
0.667 0.333 0.000
E05.9 Thyrotoxicosis, unspecified
0.667 0.333 0.000
T87 Complications peculiar to reattachment and amputation
0.667 0.333 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.667 0.333 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.666 0.334 0.000
S29 Other and unspecified injuries of thorax
0.665 0.335 0.000
D00-D09 In situ neoplasms
0.665 0.335 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.664 0.336 0.000
O82 Single delivery by Caesarean section
0.664 0.336 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.664 0.336 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.664 0.336 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.663 0.337 0.000
M50.3 Other cervical disk degeneration
0.663 0.337 0.000
O74 Complications of anaesthesia during labour and delivery
0.662 0.338 0.000
O71 Other obstetric trauma
0.662 0.338 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.662 0.338 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.662 0.338 0.000
O60 Preterm delivery
0.662 0.338 0.000
W20-W49 Exposure to inanimate mechanical forces
0.662 0.338 0.000
D53 Other nutritional anaemias
0.662 0.338 0.000
D52 Folate deficiency anaemia
0.662 0.338 0.000
E23 Hypofunction and other disorders of pituitary gland
0.662 0.338 0.000
K08 Other disorders of teeth and supporting structures
0.662 0.338 0.000
S20 Superficial injury of thorax
0.661 0.339 0.000
J00-J06 Acute upper respiratory infections
0.661 0.339 0.000
J18.8 Other pneumonia, organism unspecified
0.660 0.339 0.000
J18.2 Hypostatic pneumonia, unspecified
0.660 0.339 0.000
X60-X84 Intentional self-harm
0.660 0.340 0.000
N25-N29 Other disorders of kidney and ureter
0.660 0.340 0.000
I27 Other pulmonary heart diseases
0.658 0.342 0.000
J94 Other pleural conditions
0.657 0.343 0.000
M80-M85 Disorders of bone density and structure
0.657 0.343 0.000
E29 Testicular dysfunction
0.656 0.344 0.000
C77.5 Intrapelvic lymph nodes
0.656 0.344 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.655 0.345 0.000
C61 Malignant neoplasm of prostate
0.654 0.346 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.654 0.346 0.000
K70 Alcoholic liver disease
0.654 0.346 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.653 0.347 0.000
I35.0 Aortic (valve) stenosis
0.652 0.348 0.000
Chapter VI Diseases of the nervous system
0.652 0.348 0.000
O29 Complications of anaesthesia during pregnancy
0.652 0.348 0.000
O28 Abnormal findings on antenatal screening of mother
0.652 0.348 0.000
O24 Diabetes mellitus in pregnancy
0.652 0.348 0.000
O22 Venous complications in pregnancy
0.652 0.348 0.000
O21 Excessive vomiting in pregnancy
0.652 0.348 0.000
O25 Malnutrition in pregnancy
0.652 0.348 0.000
M05-M14 Inflammatory polyarthropathies
0.652 0.348 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.651 0.349 0.000
C64-C68 Malignant neoplasms of urinary tract
0.651 0.349 0.000
S42 Fracture of shoulder and upper arm
0.649 0.351 0.000
S22.4 Multiple fractures of ribs
0.649 0.351 0.000
N36 Other disorders of urethra
0.648 0.351 0.000
B99-B99 Other infectious diseases
0.648 0.352 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.648 0.352 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.648 0.352 0.000
B65-B83 Helminthiases
0.648 0.352 0.000
B50-B64 Protozoal diseases
0.648 0.352 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.648 0.352 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.648 0.352 0.000
A75-A79 Rickettsioses
0.648 0.352 0.000
A70-A74 Other diseases caused by chlamydiae
0.648 0.352 0.000
A65-A69 Other spirochaetal diseases
0.648 0.352 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.648 0.352 0.000
A20-A28 Certain zoonotic bacterial diseases
0.648 0.352 0.000
A15-A19 Tuberculosis
0.648 0.352 0.000
K07 Dentofacial anomalies [including malocclusion]
0.647 0.353 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.647 0.353 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.646 0.353 0.000
E66.1 Drug-induced obesity
0.646 0.353 0.000
E66.0 Obesity due to excess calories
0.646 0.353 0.000
K85.1 Biliary acute pancreatitis
0.646 0.353 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.646 0.353 0.000
S26 Injury of heart
0.646 0.353 0.000
S25 Injury of blood vessels of thorax
0.646 0.353 0.000
S24 Injury of nerves and spinal cord at thorax level
0.646 0.353 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.646 0.353 0.000
S21 Open wound of thorax
0.646 0.353 0.000
O62 Abnormalities of forces of labour
0.646 0.354 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.646 0.354 0.000
N30.4 Irradiation cystitis
0.646 0.354 0.000
O75.8 Other specified complications of labour and delivery
0.646 0.354 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.645 0.355 0.000
B15-B19 Viral hepatitis
0.645 0.355 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.642 0.358 0.000
T98 Sequelae of other and unspecified effects of external causes
0.641 0.359 0.000
T95 Sequelae of burns, corrosions and frostbite
0.641 0.359 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.641 0.359 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.641 0.359 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.641 0.359 0.000
O20 Haemorrhage in early pregnancy
0.641 0.359 0.000
C15-C26 Malignant neoplasms of digestive organs
0.640 0.360 0.000
M54.1 Radiculopathy
0.640 0.360 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.639 0.360 0.000
I49 Other cardiac arrhythmias
0.639 0.360 0.000
N42 Other disorders of prostate
0.639 0.361 0.000
O00 Ectopic pregnancy
0.639 0.361 0.000
H00 Hordeolum and chalazion
0.639 0.361 0.000
O61.0 Failed medical induction of labour
0.638 0.361 0.000
D67 Hereditary factor IX deficiency
0.637 0.363 0.000
D66 Hereditary factor VIII deficiency
0.637 0.363 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.637 0.363 0.000
J92 Pleural plaque
0.637 0.363 0.000
Y57 Other and unspecified drugs and medicaments
0.637 0.363 0.000
K83 Other diseases of biliary tract
0.636 0.364 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.636 0.364 0.000
N17 Acute renal failure
0.635 0.365 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.634 0.366 0.000
D50.1 Sideropenic dysphagia
0.634 0.366 0.000
C34 Malignant neoplasm of bronchus and lung
0.634 0.366 0.000
Q60-Q64 Congenital malformations of the urinary system
0.633 0.367 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.632 0.368 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.632 0.368 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.632 0.368 0.000
M54.9 Dorsalgia, unspecified
0.631 0.369 0.000
D51 Vitamin B12 deficiency anaemia
0.630 0.370 0.000
K81.8 Other cholecystitis
0.629 0.370 0.000
E04 Other non-toxic goitre
0.629 0.371 0.000
C79.6 Secondary malignant neoplasm of ovary
0.628 0.372 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.628 0.372 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.628 0.372 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.628 0.372 0.000
S27.0 Traumatic pneumothorax
0.627 0.373 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.627 0.373 0.000
E34 Other endocrine disorders
0.627 0.373 0.000
E32 Diseases of thymus
0.627 0.373 0.000
E31 Polyglandular dysfunction
0.627 0.373 0.000
E30 Disorders of puberty, not elsewhere classified
0.627 0.373 0.000
E26 Hyperaldosteronism
0.627 0.373 0.000
E25 Adrenogenital disorders
0.627 0.373 0.000
E24 Cushing's syndrome
0.627 0.373 0.000
E20 Hypoparathyroidism
0.627 0.373 0.000
K76.9 Liver disease, unspecified
0.627 0.373 0.000
O69.2 Labour and delivery complicated by other cord entanglement
0.626 0.373 0.000
Y43 Primarily systemic agents
0.626 0.374 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.625 0.375 0.000
O07 Failed attempted abortion
0.625 0.375 0.000
O06 Unspecified abortion
0.625 0.375 0.000
O05 Other abortion
0.625 0.375 0.000
O01 Hydatidiform mole
0.625 0.375 0.000
U80 Agent resistant to penicillin and related antibiotics
0.624 0.376 0.000
H21 Other disorders of iris and ciliary body
0.624 0.376 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.623 0.377 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.623 0.377 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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