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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs112469508
log Bayes Factor = 15.1969
Chromosome 7   position 153,176,649  (GRCh37) Explore rs112469508 on Ensembl!
Variant rs112469508 is part of Cluster X0220

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.999 0.001 0.000
M70-M79 Other soft tissue disorders
0.994 0.006 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.989 0.011 0.000
S00-S09 Injuries to the head
0.989 0.011 0.000
S60-S69 Injuries to the wrist and hand
0.988 0.012 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.983 0.017 0.000
Chapter VI Diseases of the nervous system
0.982 0.018 0.000
Chapter XI Diseases of the digestive system
0.978 0.022 0.000
I44 Atrioventricular and left bundle-branch block
0.977 0.023 0.000
M05-M14 Inflammatory polyarthropathies
0.976 0.024 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.976 0.024 0.000
S00 Superficial injury of head
0.970 0.030 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.970 0.030 0.000
M75 Shoulder lesions
0.963 0.037 0.000
I10-I15 Hypertensive diseases
0.962 0.038 0.000
E70-E90 Metabolic disorders
0.956 0.044 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.953 0.047 0.000
I12 Hypertensive renal disease
0.953 0.047 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.951 0.049 0.000
O00-O08 Pregnancy with abortive outcome
0.951 0.049 0.000
I05-I09 Chronic rheumatic heart diseases
0.946 0.054 0.000
Chapter XXI Factors influencing health status and contact with health services
0.945 0.055 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.945 0.055 0.000
O60-O75 Complications of labour and delivery
0.944 0.056 0.000
I42 Cardiomyopathy
0.941 0.059 0.000
Chapter V Mental and behavioural disorders
0.941 0.059 0.000
I12.0 Hypertensive renal disease with renal failure
0.937 0.063 0.000
M45-M49 Spondylopathies
0.937 0.063 0.000
I51 Complications and ill-defined descriptions of heart disease
0.934 0.066 0.000
I44.0 Atrioventricular block, first degree
0.931 0.069 0.000
M75.1 Rotator cuff syndrome
0.930 0.070 0.000
E83 Disorders of mineral metabolism
0.930 0.070 0.000
K04 Diseases of pulp and periapical tissues
0.928 0.072 0.000
S40-S49 Injuries to the shoulder and upper arm
0.928 0.072 0.000
K30 Dyspepsia
0.925 0.075 0.000
M06 Other rheumatoid arthritis
0.923 0.077 0.000
K14 Diseases of tongue
0.920 0.080 0.000
G40-G47 Episodic and paroxysmal disorders
0.914 0.086 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.908 0.092 0.000
E00-E07 Disorders of thyroid gland
0.905 0.095 0.000
K20 Oesophagitis
0.905 0.095 0.000
Chapter X Diseases of the respiratory system
0.902 0.098 0.000
I51.8 Other ill-defined heart diseases
0.901 0.099 0.000
O47 False labour
0.901 0.099 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.899 0.101 0.000
S80-S89 Injuries to the knee and lower leg
0.896 0.104 0.000
G40 Epilepsy
0.896 0.104 0.000
J30-J39 Other diseases of upper respiratory tract
0.895 0.105 0.000
O02 Other abnormal products of conception
0.894 0.106 0.000
M79.0 Rheumatism, unspecified
0.893 0.107 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.892 0.108 0.000
E83.5 Disorders of calcium metabolism
0.892 0.108 0.000
I34 Nonrheumatic mitral valve disorders
0.891 0.109 0.000
K07 Dentofacial anomalies [including malocclusion]
0.883 0.117 0.000
S00.8 Superficial injury of other parts of head
0.882 0.118 0.000
S61 Open wound of wrist and hand
0.876 0.124 0.000
G90-G99 Other disorders of the nervous system
0.875 0.125 0.000
M06.9 Rheumatoid arthritis, unspecified
0.875 0.125 0.000
M47 Spondylosis
0.874 0.126 0.000
J34 Other disorders of nose and nasal sinuses
0.870 0.130 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.867 0.133 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.865 0.135 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.863 0.137 0.000
K70-K77 Diseases of liver
0.862 0.138 0.000
M13 Other arthritis
0.861 0.139 0.000
K11 Diseases of salivary glands
0.859 0.141 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.856 0.144 0.000
E03 Other hypothyroidism
0.855 0.145 0.000
T39.1 4-Aminophenol derivatives
0.855 0.145 0.000
I42.0 Dilated cardiomyopathy
0.855 0.145 0.000
O03 Spontaneous abortion
0.853 0.147 0.000
M47.8 Other spondylosis
0.853 0.147 0.000
I44.7 Left bundle-branch block, unspecified
0.852 0.148 0.000
K04.5 Chronic apical periodontitis
0.850 0.150 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.849 0.151 0.000
K04.7 Periapical abscess without sinus
0.849 0.151 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.848 0.152 0.000
K22 Other diseases of oesophagus
0.848 0.152 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.848 0.152 0.000
I08 Multiple valve diseases
0.846 0.154 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.844 0.156 0.000
Z87 Personal history of other diseases and conditions
0.843 0.157 0.000
G20-G26 Extrapyramidal and movement disorders
0.840 0.160 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.839 0.161 0.000
O02.1 Missed abortion
0.838 0.162 0.000
G40.9 Epilepsy, unspecified
0.836 0.164 0.000
I12.9 Hypertensive renal disease without renal failure
0.835 0.165 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.832 0.168 0.000
K14.9 Disease of tongue, unspecified
0.832 0.168 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.824 0.176 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.824 0.176 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.824 0.176 0.000
S70-S79 Injuries to the hip and thigh
0.823 0.177 0.000
I95 Hypotension
0.821 0.179 0.000
E03.9 Hypothyroidism, unspecified
0.819 0.181 0.000
J39 Other diseases of upper respiratory tract
0.819 0.181 0.000
Z87.1 Personal history of diseases of the digestive system
0.818 0.182 0.000
I34.0 Mitral (valve) insufficiency
0.816 0.184 0.000
F30-F39 Mood [affective] disorders
0.814 0.186 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.813 0.187 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.811 0.189 0.000
Chapter VII Diseases of the eye and adnexa
0.809 0.191 0.000
Z35 Supervision of high-risk pregnancy
0.809 0.191 0.000
S69 Other and unspecified injuries of wrist and hand
0.808 0.192 0.000
S82 Fracture of lower leg, including ankle
0.807 0.193 0.000
M75.4 Impingement syndrome of shoulder
0.806 0.194 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.805 0.194 0.000
S64 Injury of nerves at wrist and hand level
0.805 0.195 0.000
J32 Chronic sinusitis
0.804 0.196 0.000
M79.6 Pain in limb
0.804 0.196 0.000
I05 Rheumatic mitral valve diseases
0.803 0.197 0.000
M91-M94 Chondropathies
0.801 0.199 0.000
S06 Intracranial injury
0.800 0.200 0.000
Z92 Personal history of medical treatment
0.800 0.200 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.800 0.200 0.000
S00.3 Superficial injury of nose
0.800 0.200 0.000
S62 Fracture at wrist and hand level
0.799 0.201 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.799 0.201 0.000
S09 Other and unspecified injuries of head
0.798 0.202 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.796 0.204 0.000
S00.1 Contusion of eyelid and periocular area
0.796 0.204 0.000
I50 Heart failure
0.795 0.205 0.000
I49 Other cardiac arrhythmias
0.794 0.206 0.000
M47.86 Other spondylosis (Lumbar region)
0.794 0.206 0.000
I33 Acute and subacute endocarditis
0.792 0.208 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.792 0.208 0.000
Chapter XX External causes of morbidity and mortality
0.791 0.209 0.000
E83.1 Disorders of iron metabolism
0.790 0.210 0.000
S65 Injury of blood vessels at wrist and hand level
0.790 0.210 0.000
K07.6 Temporomandibular joint disorders
0.789 0.211 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.788 0.212 0.000
E87.6 Hypokalaemia
0.787 0.213 0.000
I44.6 Other and unspecified fascicular block
0.786 0.214 0.000
M20-M25 Other joint disorders
0.783 0.217 0.000
Z94 Transplanted organ and tissue status
0.782 0.218 0.000
I51.9 Heart disease, unspecified
0.782 0.218 0.000
E87.2 Acidosis
0.781 0.219 0.000
S00.0 Superficial injury of scalp
0.780 0.220 0.000
G30-G32 Other degenerative diseases of the nervous system
0.779 0.221 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.778 0.222 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.778 0.222 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.778 0.222 0.000
O42 Premature rupture of membranes
0.777 0.223 0.000
M75.5 Bursitis of shoulder
0.776 0.224 0.000
M79.7 Fibromyalgia
0.770 0.230 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.770 0.230 0.000
E20-E35 Disorders of other endocrine glands
0.770 0.230 0.000
K14.0 Glossitis
0.770 0.230 0.000
M80-M85 Disorders of bone density and structure
0.768 0.232 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.767 0.233 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.765 0.235 0.000
I95.9 Hypotension, unspecified
0.764 0.236 0.000
I45 Other conduction disorders
0.763 0.237 0.000
I42.2 Other hypertrophic cardiomyopathy
0.762 0.238 0.000
M47.82 Other spondylosis (Cervical region)
0.762 0.238 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.762 0.238 0.000
T66-T78 Other and unspecified effects of external causes
0.761 0.239 0.000
O73 Retained placenta and membranes, without haemorrhage
0.761 0.239 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.761 0.239 0.000
O62 Abnormalities of forces of labour
0.760 0.240 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.760 0.240 0.000
G70-G73 Diseases of myoneural junction and muscle
0.757 0.243 0.000
O80-O84 Delivery
0.757 0.243 0.000
M79.1 Myalgia
0.755 0.245 0.000
J39.2 Other diseases of pharynx
0.755 0.245 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.754 0.246 0.000
Chapter XXII Codes for special purposes
0.752 0.247 0.000
M86-M90 Other osteopathies
0.752 0.248 0.000
M11 Other crystal arthropathies
0.752 0.248 0.000
S01 Open wound of head
0.752 0.248 0.000
I07 Rheumatic tricuspid valve diseases
0.751 0.249 0.000
T42.4 Benzodiazepines
0.750 0.250 0.000
S49.9 Unspecified injury of shoulder and upper arm
0.749 0.251 0.000
I38 Endocarditis, valve unspecified
0.748 0.252 0.000
I44.1 Atrioventricular block, second degree
0.747 0.253 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.747 0.253 0.000
S10-S19 Injuries to the neck
0.747 0.253 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.746 0.254 0.000
S82.5 Fracture of medial malleolus
0.745 0.255 0.000
O36 Maternal care for other known or suspected foetal problems
0.745 0.255 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.745 0.255 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.745 0.255 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.744 0.256 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.744 0.256 0.000
K09 Cysts of oral region, not elsewhere classified
0.743 0.257 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.741 0.259 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.741 0.259 0.000
M13.9 Arthritis, unspecified
0.741 0.259 0.000
O41 Other disorders of amniotic fluid and membranes
0.741 0.259 0.000
I47 Paroxysmal tachycardia
0.740 0.260 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.740 0.260 0.000
S67 Crushing injury of wrist and hand
0.739 0.261 0.000
K22.1 Ulcer of oesophagus
0.739 0.261 0.000
Z36 Antenatal screening
0.738 0.261 0.000
I50.0 Congestive heart failure
0.738 0.262 0.000
M75.9 Shoulder lesion, unspecified
0.738 0.262 0.000
O03.4 Incomplete, without complication
0.737 0.263 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.735 0.265 0.000
K70 Alcoholic liver disease
0.734 0.266 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.734 0.266 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.733 0.267 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.733 0.267 0.000
K11.8 Other diseases of salivary glands
0.733 0.267 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.732 0.268 0.000
J30 Vasomotor and allergic rhinitis
0.731 0.269 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.729 0.270 0.000
F32 Depressive episode
0.728 0.272 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.728 0.272 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.727 0.273 0.000
Z32 Pregnancy examination and test
0.727 0.273 0.000
S00.9 Superficial injury of head, part unspecified
0.726 0.274 0.000
M06.3 Rheumatoid nodule
0.726 0.274 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.726 0.274 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.724 0.275 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.724 0.276 0.000
S61.0 Open wound of finger(s) without damage to nail
0.724 0.276 0.000
M05 Seropositive rheumatoid arthritis
0.723 0.277 0.000
E04 Other non-toxic goitre
0.723 0.277 0.000
O72 Postpartum haemorrhage
0.723 0.277 0.000
Z34 Supervision of normal pregnancy
0.722 0.278 0.000
Z94.8 Other transplanted organ and tissue status
0.722 0.278 0.000
S90-S99 Injuries to the ankle and foot
0.721 0.279 0.000
Z87.0 Personal history of diseases of the respiratory system
0.721 0.279 0.000
M20 Acquired deformities of fingers and toes
0.720 0.280 0.000
M77 Other enthesopathies
0.720 0.280 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.719 0.281 0.000
K22.7 Barrett's oesophagus
0.718 0.282 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.717 0.282 0.000
K08 Other disorders of teeth and supporting structures
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I30 Acute pericarditis
0.717 0.283 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.716 0.284 0.000
O85-O92 Complications predominantly related to the puerperium
0.716 0.284 0.000
J32.0 Chronic maxillary sinusitis
0.716 0.284 0.000
G93 Other disorders of brain
0.715 0.285 0.000
K12 Stomatitis and related lesions
0.714 0.285 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.713 0.287 0.000
M76 Enthesopathies of lower limb, excluding foot
0.713 0.287 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.713 0.287 0.000
M71 Other bursopathies
0.713 0.287 0.000
K14.8 Other diseases of tongue
0.713 0.287 0.000
M46 Other inflammatory spondylopathies
0.712 0.288 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.711 0.289 0.000
M48 Other spondylopathies
0.711 0.289 0.000
M40-M43 Deforming dorsopathies
0.710 0.290 0.000
O02.0 Blighted ovum and nonhydatidiform mole
0.710 0.290 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.710 0.290 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.710 0.290 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.709 0.291 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.709 0.291 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.709 0.291 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.709 0.291 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.709 0.291 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.709 0.291 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.709 0.291 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.709 0.291 0.000
T36 Poisoning by systemic antibiotics
0.709 0.291 0.000
S08 Traumatic amputation of part of head
0.709 0.291 0.000
S07 Crushing injury of head
0.709 0.291 0.000
S05 Injury of eye and orbit
0.709 0.291 0.000
S04 Injury of cranial nerves
0.709 0.291 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.709 0.291 0.000
S60 Superficial injury of wrist and hand
0.709 0.291 0.000
O03.9 Complete or unspecified, without complication
0.708 0.292 0.000
Z39 Postpartum care and examination
0.708 0.292 0.000
K07.3 Anomalies of tooth position
0.707 0.293 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.707 0.293 0.000
S80 Superficial injury of lower leg
0.706 0.294 0.000
E40-E46 Malnutrition
0.705 0.295 0.000
S40 Superficial injury of shoulder and upper arm
0.705 0.295 0.000
F60-F69 Disorders of adult personality and behaviour
0.705 0.295 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.704 0.296 0.000
Z13 Special screening examination for other diseases and disorders
0.704 0.296 0.000
T39.0 Salicylates
0.703 0.297 0.000
F99-F99 Unspecified mental disorder
0.702 0.298 0.000
I11 Hypertensive heart disease
0.702 0.298 0.000
O70 Perineal laceration during delivery
0.701 0.299 0.000
Z92.0 Personal history of contraception
0.701 0.299 0.000
S82.50 Fracture of medial malleolus (closed)
0.701 0.299 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.701 0.299 0.000
I44.5 Left posterior fascicular block
0.700 0.300 0.000
I44.4 Left anterior fascicular block
0.700 0.300 0.000
I44.3 Other and unspecified atrioventricular block
0.700 0.300 0.000
K74 Fibrosis and cirrhosis of liver
0.700 0.300 0.000
O32.1 Maternal care for breech presentation
0.700 0.300 0.000
M14 Arthropathies in other diseases classified elsewhere
0.700 0.300 0.000
M12 Other specific arthropathies
0.700 0.300 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.700 0.300 0.000
M08 Juvenile arthritis
0.700 0.300 0.000
K10 Other diseases of jaws
0.700 0.300 0.000
K03 Other diseases of hard tissues of teeth
0.700 0.300 0.000
K00 Disorders of tooth development and eruption
0.700 0.300 0.000
S02 Fracture of skull and facial bones
0.699 0.301 0.000
M72 Fibroblastic disorders
0.699 0.301 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.698 0.301 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.698 0.302 0.000
K05 Gingivitis and periodontal diseases
0.698 0.302 0.000
M79.67 Pain in limb (Ankle and foot)
0.697 0.303 0.000
S00.7 Multiple superficial injuries of head
0.696 0.304 0.000
S00.5 Superficial injury of lip and oral cavity
0.696 0.304 0.000
S00.4 Superficial injury of ear
0.696 0.304 0.000
K27 Peptic ulcer, site unspecified
0.696 0.304 0.000
O45 Premature separation of placenta [abruptio placentae]
0.695 0.304 0.000
O44 Placenta praevia
0.695 0.304 0.000
O43 Placental disorders
0.695 0.304 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.695 0.304 0.000
O33 Maternal care for known or suspected disproportion
0.695 0.304 0.000
O31 Complications specific to multiple gestation
0.695 0.304 0.000
O40 Polyhydramnios
0.695 0.304 0.000
E83.3 Disorders of phosphorus metabolism
0.695 0.305 0.000
M13.0 Polyarthritis, unspecified
0.694 0.306 0.000
M10 Gout
0.694 0.306 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.692 0.308 0.000
G96 Other disorders of central nervous system
0.692 0.308 0.000
M07 Psoriatic and enteropathic arthropathies
0.691 0.309 0.000
Z35.1 Supervision of pregnancy with history of abortive outcome
0.691 0.309 0.000
M75.8 Other shoulder lesions
0.690 0.310 0.000
M75.2 Bicipital tendinitis
0.690 0.310 0.000
I15 Secondary hypertension
0.690 0.310 0.000
I13 Hypertensive heart and renal disease
0.690 0.310 0.000
I46 Cardiac arrest
0.689 0.311 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.689 0.311 0.000
Z37 Outcome of delivery
0.688 0.312 0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities
0.687 0.313 0.000
M50-M54 Other dorsopathies
0.687 0.313 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.686 0.314 0.000
M79.5 Residual foreign body in soft tissue
0.685 0.315 0.000
E85 Amyloidosis
0.685 0.315 0.000
E84 Cystic fibrosis
0.685 0.315 0.000
E79 Disorders of purine and pyrimidine metabolism
0.685 0.315 0.000
E77 Disorders of glycoprotein metabolism
0.685 0.315 0.000
E76 Disorders of glycosaminoglycan metabolism
0.685 0.315 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.685 0.315 0.000
E74 Other disorders of carbohydrate metabolism
0.685 0.315 0.000
E73 Lactose intolerance
0.685 0.315 0.000
E72 Other disorders of amino-acid metabolism
0.685 0.315 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.685 0.315 0.000
E70 Disorders of aromatic amino-acid metabolism
0.685 0.315 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.685 0.315 0.000
I42.9 Cardiomyopathy, unspecified
0.685 0.315 0.000
M79.9 Soft tissue disorder, unspecified
0.683 0.317 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.683 0.317 0.000
M79.3 Panniculitis, unspecified
0.683 0.317 0.000
M79.2 Neuralgia and neuritis, unspecified
0.683 0.317 0.000
K28 Gastrojejunal ulcer
0.682 0.318 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.682 0.318 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.681 0.318 0.000
O07 Failed attempted abortion
0.681 0.318 0.000
O06 Unspecified abortion
0.681 0.318 0.000
O05 Other abortion
0.681 0.318 0.000
O01 Hydatidiform mole
0.681 0.318 0.000
G20 Parkinson's disease
0.681 0.319 0.000
E87.3 Alkalosis
0.679 0.321 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.679 0.321 0.000
S61.8 Open wound of other parts of wrist and hand
0.679 0.321 0.000
S69.9 Unspecified injury of wrist and hand
0.679 0.321 0.000
I09 Other rheumatic heart diseases
0.678 0.322 0.000
I06 Rheumatic aortic valve diseases
0.678 0.322 0.000
H53-H54 Visual disturbances and blindness
0.678 0.322 0.000
G25 Other extrapyramidal and movement disorders
0.678 0.322 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.678 0.322 0.000
F10.0 Acute intoxication
0.678 0.322 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.677 0.323 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.677 0.323 0.000
T39.4 Antirheumatics, not elsewhere classified
0.677 0.323 0.000
T39.2 Pyrazolone derivatives
0.677 0.323 0.000
O74 Complications of anaesthesia during labour and delivery
0.677 0.323 0.000
O71 Other obstetric trauma
0.677 0.323 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.677 0.323 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.677 0.323 0.000
O61 Failed induction of labour
0.677 0.323 0.000
O60 Preterm delivery
0.677 0.323 0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome
0.677 0.323 0.000
K11.2 Sialoadenitis
0.677 0.323 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.676 0.323 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.676 0.324 0.000
S42 Fracture of shoulder and upper arm
0.676 0.324 0.000
K22.5 Diverticulum of oesophagus, acquired
0.676 0.324 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.675 0.325 0.000
I42.8 Other cardiomyopathies
0.675 0.325 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.675 0.325 0.000
I42.6 Alcoholic cardiomyopathy
0.675 0.325 0.000
I42.5 Other restrictive cardiomyopathy
0.675 0.325 0.000
I42.4 Endocardial fibroelastosis
0.675 0.325 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.675 0.325 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.675 0.325 0.000
F70-F79 Mental retardation
0.675 0.325 0.000
I05.9 Mitral valve disease, unspecified
0.675 0.325 0.000
E88 Other metabolic disorders
0.675 0.325 0.000
Z89 Acquired absence of limb
0.674 0.326 0.000
H10-H13 Disorders of conjunctiva
0.673 0.327 0.000
S64.4 Injury of digital nerve of other finger
0.673 0.327 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.672 0.328 0.000
M49 Spondylopathies in diseases classified elsewhere
0.671 0.328 0.000
M45 Ankylosing spondylitis
0.671 0.328 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.671 0.328 0.000
I51.6 Cardiovascular disease, unspecified
0.670 0.330 0.000
I51.5 Myocardial degeneration
0.670 0.330 0.000
I51.4 Myocarditis, unspecified
0.670 0.330 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.670 0.330 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.670 0.330 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.670 0.330 0.000
I51.0 Cardiac septal defect, acquired
0.670 0.330 0.000
F80-F89 Disorders of psychological development
0.670 0.330 0.000
Z97 Presence of other devices
0.670 0.330 0.000
S62.3 Fracture of other metacarpal bone
0.669 0.331 0.000
W20-W49 Exposure to inanimate mechanical forces
0.669 0.331 0.000
O66 Other obstructed labour
0.668 0.331 0.000
S82.6 Fracture of lateral malleolus
0.668 0.332 0.000
I49.8 Other specified cardiac arrhythmias
0.668 0.332 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.668 0.332 0.000
S32 Fracture of lumbar spine and pelvis
0.667 0.333 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.667 0.333 0.000
E83.8 Other disorders of mineral metabolism
0.667 0.333 0.000
E83.2 Disorders of zinc metabolism
0.667 0.333 0.000
E83.0 Disorders of copper metabolism
0.667 0.333 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.667 0.333 0.000
K04.9 Other and unspecified diseases of pulp and periapical tissues
0.666 0.334 0.000
K04.6 Periapical abscess with sinus
0.666 0.334 0.000
K04.4 Acute apical periodontitis of pulpal origin
0.666 0.334 0.000
K04.3 Abnormal hard tissue formation in pulp
0.666 0.334 0.000
K04.2 Pulp degeneration
0.666 0.334 0.000
K04.1 Necrosis of pulp
0.666 0.334 0.000
K04.0 Pulpitis
0.666 0.334 0.000
S48 Traumatic amputation of shoulder and upper arm
0.665 0.335 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.665 0.335 0.000
S44 Injury of nerves at shoulder and upper arm level
0.665 0.335 0.000
S41 Open wound of shoulder and upper arm
0.665 0.335 0.000
S47 Crushing injury of shoulder and upper arm
0.665 0.335 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.665 0.335 0.000
I35 Nonrheumatic aortic valve disorders
0.665 0.335 0.000
O47.0 False labour before 37 completed weeks of gestation
0.665 0.335 0.000
Z87.4 Personal history of diseases of the genito-urinary system
0.664 0.336 0.000
S68 Traumatic amputation of wrist and hand
0.664 0.336 0.000
E83.4 Disorders of magnesium metabolism
0.664 0.336 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.664 0.336 0.000
M06.8 Other specified rheumatoid arthritis
0.662 0.338 0.000
M06.4 Inflammatory polyarthropathy
0.662 0.338 0.000
M06.2 Rheumatoid bursitis
0.662 0.338 0.000
M06.1 Adult-onset Still's disease
0.662 0.338 0.000
M65-M68 Disorders of synovium and tendon
0.662 0.338 0.000
Z30 Contraceptive management
0.662 0.338 0.000
S09.9 Unspecified injury of head
0.661 0.339 0.000
Z13.6 Special screening examination for cardiovascular disorders
0.661 0.339 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.660 0.340 0.000
D68 Other coagulation defects
0.660 0.340 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.660 0.340 0.000
K14.6 Glossodynia
0.659 0.341 0.000
K14.5 Plicated tongue
0.659 0.341 0.000
K14.4 Atrophy of tongue papillae
0.659 0.341 0.000
K14.3 Hypertrophy of tongue papillae
0.659 0.341 0.000
K14.2 Median rhomboid glossitis
0.659 0.341 0.000
K14.1 Geographic tongue
0.659 0.341 0.000
E65-E68 Obesity and other hyperalimentation
0.659 0.341 0.000
E07 Other disorders of thyroid
0.659 0.341 0.000
T40.2 Other opioids
0.658 0.342 0.000
M06.0 Seronegative rheumatoid arthritis
0.658 0.342 0.000
J84 Other interstitial pulmonary diseases
0.658 0.342 0.000
T43.2 Other and unspecified antidepressants
0.658 0.342 0.000
G30 Alzheimer's disease
0.658 0.342 0.000
T40.4 Other synthetic narcotics
0.657 0.343 0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified
0.656 0.344 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.655 0.345 0.000
G41 Status epilepticus
0.655 0.345 0.000
T17 Foreign body in respiratory tract
0.655 0.345 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.654 0.346 0.000
E87.0 Hyperosmolality and hypernatraemia
0.653 0.347 0.000
F11 Mental and behavioural disorders due to use of opioids
0.653 0.347 0.000
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history
0.651 0.349 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.651 0.349 0.000
Z38 Liveborn infants according to place of birth
0.651 0.349 0.000
Z31 Procreative management
0.651 0.349 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.650 0.350 0.000
E89.0 Postprocedural hypothyroidism
0.650 0.350 0.000
M79.00 Rheumatism, unspecified (Multiple sites)
0.650 0.350 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.649 0.350 0.000
E06 Thyroiditis
0.649 0.351 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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