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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs112472535
log Bayes Factor = 16.0956
Chromosome 3   position 130,285,880  (GRCh37) Explore rs112472535 on Ensembl!
Variant rs112472535 is part of Cluster X0070

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.998 0.002 0.000
D10-D36 Benign neoplasms
0.997 0.003 0.000
F30-F39 Mood [affective] disorders
0.996 0.004 0.000
F32 Depressive episode
0.989 0.011 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.985 0.015 0.000
Chapter X Diseases of the respiratory system
0.981 0.019 0.000
E70-E90 Metabolic disorders
0.977 0.023 0.000
Chapter IX Diseases of the circulatory system
0.975 0.025 0.000
F32.9 Depressive episode, unspecified
0.975 0.025 0.000
Chapter XI Diseases of the digestive system
0.974 0.026 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.972 0.028 0.000
I20-I25 Ischaemic heart diseases
0.969 0.031 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.968 0.032 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.964 0.036 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.962 0.038 0.000
Chapter I Certain infectious and parasitic diseases
0.960 0.040 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.947 0.053 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.947 0.053 0.000
J40-J47 Chronic lower respiratory diseases
0.945 0.055 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.945 0.055 0.000
D22 Melanocytic naevi
0.942 0.058 0.000
B35-B49 Mycoses
0.940 0.060 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.935 0.065 0.000
K55-K64 Other diseases of intestines
0.932 0.068 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.932 0.068 0.000
D23 Other benign neoplasms of skin
0.931 0.069 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.928 0.072 0.000
I20 Angina pectoris
0.925 0.075 0.000
B37 Candidiasis
0.920 0.080 0.000
R26 Abnormalities of gait and mobility
0.919 0.081 0.000
E87.6 Hypokalaemia
0.918 0.082 0.000
S00-S09 Injuries to the head
0.918 0.082 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.918 0.082 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.917 0.083 0.000
Chapter XX External causes of morbidity and mortality
0.916 0.084 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.913 0.087 0.000
Chapter VIII Diseases of the ear and mastoid process
0.912 0.088 0.000
F41 Other anxiety disorders
0.911 0.089 0.000
K57 Diverticular disease of intestine
0.910 0.090 0.000
E87.2 Acidosis
0.900 0.100 0.000
S60-S69 Injuries to the wrist and hand
0.898 0.101 0.000
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess
0.896 0.104 0.000
I20.9 Angina pectoris, unspecified
0.894 0.106 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.891 0.109 0.000
B37.0 Candidal stomatitis
0.889 0.111 0.000
S40-S49 Injuries to the shoulder and upper arm
0.884 0.116 0.000
O00-O08 Pregnancy with abortive outcome
0.882 0.118 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.880 0.120 0.000
D70 Agranulocytosis
0.880 0.120 0.000
K70-K77 Diseases of liver
0.879 0.121 0.000
J47 Bronchiectasis
0.875 0.125 0.000
I25 Chronic ischaemic heart disease
0.873 0.127 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.871 0.129 0.000
E86 Volume depletion
0.867 0.133 0.000
J44 Other chronic obstructive pulmonary disease
0.866 0.134 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.862 0.138 0.000
D00-D09 In situ neoplasms
0.862 0.138 0.000
D23.6 Skin of upper limb, including shoulder
0.861 0.139 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.861 0.139 0.000
C91 Lymphoid leukaemia
0.860 0.140 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.858 0.142 0.000
J30-J39 Other diseases of upper respiratory tract
0.850 0.150 0.000
K82 Other diseases of gallbladder
0.849 0.151 0.000
A30-A49 Other bacterial diseases
0.848 0.152 0.000
R47-R49 Symptoms and signs involving speech and voice
0.845 0.155 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.843 0.157 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.843 0.157 0.000
E10-E14 Diabetes mellitus
0.843 0.157 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.842 0.158 0.000
I24 Other acute ischaemic heart diseases
0.841 0.159 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.841 0.159 0.000
K81 Cholecystitis
0.839 0.161 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.839 0.161 0.000
F33 Recurrent depressive disorder
0.838 0.162 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.835 0.165 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.834 0.166 0.000
H65-H75 Diseases of middle ear and mastoid
0.826 0.174 0.000
I74 Arterial embolism and thrombosis
0.825 0.175 0.000
R79 Other abnormal findings of blood chemistry
0.822 0.178 0.000
J60-J70 Lung diseases due to external agents
0.822 0.178 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.820 0.180 0.000
D17 Benign lipomatous neoplasm
0.820 0.180 0.000
F31 Bipolar affective disorder
0.819 0.181 0.000
O60-O75 Complications of labour and delivery
0.818 0.182 0.000
Chapter XXII Codes for special purposes
0.816 0.184 0.000
R73 Elevated blood glucose level
0.816 0.184 0.000
D80-D89 Certain disorders involving the immune mechanism
0.811 0.189 0.000
F60-F69 Disorders of adult personality and behaviour
0.811 0.189 0.000
C44 Other malignant neoplasms of skin
0.809 0.191 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.809 0.191 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.805 0.195 0.000
D23.5 Skin of trunk
0.804 0.196 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.801 0.198 0.000
D11 Benign neoplasm of major salivary glands
0.801 0.198 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.797 0.203 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.796 0.204 0.000
S80-S89 Injuries to the knee and lower leg
0.795 0.205 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.795 0.205 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.795 0.205 0.000
D26 Other benign neoplasms of uterus
0.794 0.206 0.000
D22.9 Melanocytic naevi, unspecified
0.793 0.207 0.000
T42.4 Benzodiazepines
0.793 0.207 0.000
J95-J99 Other diseases of the respiratory system
0.793 0.207 0.000
O04 Medical abortion
0.793 0.207 0.000
D18 Haemangioma and lymphangioma, any site
0.793 0.207 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.791 0.209 0.000
D22.3 Melanocytic naevi of other and unspecified parts of face
0.791 0.209 0.000
K63 Other diseases of intestine
0.786 0.214 0.000
K70 Alcoholic liver disease
0.786 0.214 0.000
I72 Other aneurysm
0.786 0.214 0.000
K59 Other functional intestinal disorders
0.786 0.214 0.000
K81.9 Cholecystitis, unspecified
0.785 0.215 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.784 0.215 0.000
E87.0 Hyperosmolality and hypernatraemia
0.783 0.217 0.000
D24 Benign neoplasm of breast
0.782 0.218 0.000
F40 Phobic anxiety disorders
0.782 0.218 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.781 0.219 0.000
E14 Unspecified diabetes mellitus
0.781 0.219 0.000
C91.1 Chronic lymphocytic leukaemia
0.780 0.220 0.000
J09-J18 Influenza and pneumonia
0.779 0.221 0.000
F41.9 Anxiety disorder, unspecified
0.777 0.223 0.000
Chapter XIV Diseases of the genitourinary system
0.777 0.223 0.000
F32.0 Mild depressive episode
0.776 0.224 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.774 0.226 0.000
F80-F89 Disorders of psychological development
0.774 0.226 0.000
D75 Other diseases of blood and blood-forming organs
0.773 0.227 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.773 0.227 0.000
S01 Open wound of head
0.771 0.229 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.769 0.231 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.769 0.231 0.000
D32 Benign neoplasm of meninges
0.768 0.232 0.000
I21 Acute myocardial infarction
0.768 0.232 0.000
J43 Emphysema
0.768 0.232 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.768 0.232 0.000
K50-K52 Noninfective enteritis and colitis
0.768 0.232 0.000
L50-L54 Urticaria and erythema
0.766 0.234 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.765 0.235 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.763 0.237 0.000
F41.2 Mixed anxiety and depressive disorder
0.763 0.237 0.000
I60-I69 Cerebrovascular diseases
0.762 0.238 0.000
C34 Malignant neoplasm of bronchus and lung
0.761 0.238 0.000
S70-S79 Injuries to the hip and thigh
0.761 0.239 0.000
C79 Secondary malignant neoplasm of other sites
0.761 0.239 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.759 0.241 0.000
D22.6 Melanocytic naevi of upper limb, including shoulder
0.759 0.241 0.000
F32.1 Moderate depressive episode
0.759 0.241 0.000
E40-E46 Malnutrition
0.758 0.241 0.000
S90-S99 Injuries to the ankle and foot
0.758 0.242 0.000
K35-K38 Diseases of appendix
0.758 0.242 0.000
K80 Cholelithiasis
0.757 0.243 0.000
D23.4 Skin of scalp and neck
0.756 0.244 0.000
O02 Other abnormal products of conception
0.755 0.245 0.000
S02 Fracture of skull and facial bones
0.754 0.246 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.754 0.246 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.754 0.246 0.000
V10-V19 Pedal cyclist injured in transport accident
0.753 0.247 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.753 0.247 0.000
R26.3 Immobility
0.753 0.247 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.753 0.247 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.752 0.248 0.000
D22.2 Melanocytic naevi of ear and external auricular canal
0.752 0.248 0.000
B37.3 Candidiasis of vulva and vagina
0.751 0.249 0.000
L40-L45 Papulosquamous disorders
0.750 0.250 0.000
S20-S29 Injuries to the thorax
0.749 0.250 0.000
D36 Benign neoplasm of other and unspecified sites
0.749 0.251 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.748 0.252 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.747 0.253 0.000
B35 Dermatophytosis
0.747 0.253 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.745 0.254 0.000
I20.0 Unstable angina
0.745 0.255 0.000
D10 Benign neoplasm of mouth and pharynx
0.744 0.256 0.000
F43 Reaction to severe stress, and adjustment disorders
0.742 0.257 0.000
E20-E35 Disorders of other endocrine glands
0.742 0.258 0.000
S68 Traumatic amputation of wrist and hand
0.741 0.259 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.741 0.259 0.000
I21.9 Acute myocardial infarction, unspecified
0.740 0.260 0.000
A41 Other septicaemia
0.739 0.261 0.000
C15-C26 Malignant neoplasms of digestive organs
0.738 0.262 0.000
K63.9 Disease of intestine, unspecified
0.736 0.264 0.000
R25 Abnormal involuntary movements
0.736 0.264 0.000
F20 Schizophrenia
0.735 0.265 0.000
E80.4 Gilbert's syndrome
0.734 0.266 0.000
R47 Speech disturbances, not elsewhere classified
0.734 0.266 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.733 0.266 0.000
I70 Atherosclerosis
0.732 0.268 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.731 0.269 0.000
C50-C50 Malignant neoplasm of breast
0.731 0.269 0.000
C81 Hodgkin's disease
0.730 0.269 0.000
O04.9 Complete or unspecified, without complication
0.729 0.271 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.728 0.272 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.728 0.272 0.000
E14.9 Without complications
0.727 0.273 0.000
D22.4 Melanocytic naevi of scalp and neck
0.727 0.273 0.000
H60-H62 Diseases of external ear
0.726 0.274 0.000
J33 Nasal polyp
0.726 0.274 0.000
I22 Subsequent myocardial infarction
0.725 0.275 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.725 0.275 0.000
F33.9 Recurrent depressive disorder, unspecified
0.724 0.276 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.724 0.276 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.724 0.276 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.722 0.278 0.000
F99-F99 Unspecified mental disorder
0.722 0.278 0.000
S00 Superficial injury of head
0.721 0.279 0.000
K85 Acute pancreatitis
0.721 0.279 0.000
S06 Intracranial injury
0.721 0.279 0.000
R73.0 Abnormal glucose tolerance test
0.720 0.280 0.000
C44.2 Skin of ear and external auricular canal
0.719 0.281 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.718 0.282 0.000
J46 Status asthmaticus
0.718 0.282 0.000
C64-C68 Malignant neoplasms of urinary tract
0.718 0.282 0.000
N20-N23 Urolithiasis
0.717 0.283 0.000
T66-T78 Other and unspecified effects of external causes
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
F70-F79 Mental retardation
0.717 0.283 0.000
W20-W49 Exposure to inanimate mechanical forces
0.717 0.283 0.000
B37.9 Candidiasis, unspecified
0.716 0.284 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.716 0.284 0.000
C92 Myeloid leukaemia
0.715 0.284 0.000
M45-M49 Spondylopathies
0.715 0.284 0.000
T79-T79 Certain early complications of trauma
0.715 0.285 0.000
T33-T35 Frostbite
0.715 0.285 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.715 0.285 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.715 0.285 0.000
T00-T07 Injuries involving multiple body regions
0.715 0.285 0.000
S10-S19 Injuries to the neck
0.715 0.285 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.715 0.285 0.000
D31 Benign neoplasm of eye and adnexa
0.715 0.285 0.000
D30 Benign neoplasm of urinary organs
0.715 0.285 0.000
D29 Benign neoplasm of male genital organs
0.715 0.285 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.715 0.285 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.715 0.285 0.000
D19 Benign neoplasm of mesothelial tissue
0.715 0.285 0.000
D16 Benign neoplasm of bone and articular cartilage
0.715 0.285 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.715 0.285 0.000
F38 Other mood [affective] disorders
0.714 0.286 0.000
F34 Persistent mood [affective] disorders
0.714 0.286 0.000
F30 Manic episode
0.714 0.286 0.000
F39 Unspecified mood [affective] disorder
0.714 0.286 0.000
S42 Fracture of shoulder and upper arm
0.713 0.287 0.000
J30 Vasomotor and allergic rhinitis
0.713 0.287 0.000
D45 Polycythaemia vera
0.713 0.287 0.000
H65 Nonsuppurative otitis media
0.713 0.287 0.000
D86 Sarcoidosis
0.711 0.289 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.711 0.289 0.000
F32.8 Other depressive episodes
0.709 0.291 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.709 0.291 0.000
J69 Pneumonitis due to solids and liquids
0.708 0.292 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.706 0.294 0.000
Y43 Primarily systemic agents
0.706 0.294 0.000
Chapter XXI Factors influencing health status and contact with health services
0.705 0.295 0.000
K82.1 Hydrops of gallbladder
0.704 0.296 0.000
D22.0 Melanocytic naevi of lip
0.702 0.297 0.000
O63 Long labour
0.702 0.298 0.000
C44.4 Skin of scalp and neck
0.702 0.298 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.701 0.299 0.000
M47 Spondylosis
0.701 0.299 0.000
K82.8 Other specified diseases of gallbladder
0.701 0.299 0.000
E88 Other metabolic disorders
0.701 0.299 0.000
E85 Amyloidosis
0.701 0.299 0.000
E84 Cystic fibrosis
0.701 0.299 0.000
E79 Disorders of purine and pyrimidine metabolism
0.701 0.299 0.000
E77 Disorders of glycoprotein metabolism
0.701 0.299 0.000
E76 Disorders of glycosaminoglycan metabolism
0.701 0.299 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.701 0.299 0.000
E74 Other disorders of carbohydrate metabolism
0.701 0.299 0.000
E73 Lactose intolerance
0.701 0.299 0.000
E72 Other disorders of amino-acid metabolism
0.701 0.299 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.701 0.299 0.000
E70 Disorders of aromatic amino-acid metabolism
0.701 0.299 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.701 0.299 0.000
R82 Other abnormal findings in urine
0.700 0.300 0.000
E87.5 Hyperkalaemia
0.699 0.300 0.000
I00-I02 Acute rheumatic fever
0.699 0.301 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.698 0.302 0.000
C51-C58 Malignant neoplasms of female genital organs
0.698 0.302 0.000
D12.2 Ascending colon
0.698 0.302 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.697 0.303 0.000
C95 Leukaemia of unspecified cell type
0.697 0.303 0.000
C94 Other leukaemias of specified cell type
0.697 0.303 0.000
C93 Monocytic leukaemia
0.697 0.303 0.000
C88 Malignant immunoproliferative diseases
0.697 0.303 0.000
C86 Other specified types of T/NK-cell lymphoma
0.697 0.303 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.697 0.303 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.696 0.304 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.696 0.304 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.695 0.305 0.000
I23 Certain current complications following acute myocardial infarction
0.695 0.305 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.694 0.306 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.693 0.306 0.000
R80 Isolated proteinuria
0.693 0.307 0.000
K65-K67 Diseases of peritoneum
0.693 0.307 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.692 0.308 0.000
D03 Melanoma in situ
0.692 0.308 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.691 0.309 0.000
E87.4 Mixed disorder of acid-base balance
0.691 0.309 0.000
E87.3 Alkalosis
0.691 0.309 0.000
F41.1 Generalised anxiety disorder
0.690 0.309 0.000
K60 Fissure and fistula of anal and rectal regions
0.690 0.310 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.690 0.310 0.000
S64 Injury of nerves at wrist and hand level
0.690 0.310 0.000
H72 Perforation of tympanic membrane
0.690 0.310 0.000
F48 Other neurotic disorders
0.690 0.310 0.000
F45 Somatoform disorders
0.690 0.310 0.000
F44 Dissociative [conversion] disorders
0.690 0.310 0.000
F42 Obsessive-compulsive disorder
0.690 0.310 0.000
B99-B99 Other infectious diseases
0.688 0.311 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.688 0.311 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.688 0.311 0.000
B65-B83 Helminthiases
0.688 0.311 0.000
B50-B64 Protozoal diseases
0.688 0.311 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.688 0.311 0.000
B15-B19 Viral hepatitis
0.688 0.311 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.688 0.311 0.000
A80-A89 Viral infections of the central nervous system
0.688 0.311 0.000
A75-A79 Rickettsioses
0.688 0.311 0.000
A70-A74 Other diseases caused by chlamydiae
0.688 0.311 0.000
A65-A69 Other spirochaetal diseases
0.688 0.311 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.688 0.311 0.000
A20-A28 Certain zoonotic bacterial diseases
0.688 0.311 0.000
A15-A19 Tuberculosis
0.688 0.311 0.000
J35 Chronic diseases of tonsils and adenoids
0.688 0.312 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.688 0.312 0.000
F29 Unspecified nonorganic psychosis
0.687 0.313 0.000
C44.5 Skin of trunk
0.687 0.313 0.000
K74 Fibrosis and cirrhosis of liver
0.686 0.314 0.000
K82.4 Cholesterolosis of gallbladder
0.686 0.314 0.000
R76 Other abnormal immunological findings in serum
0.685 0.315 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.685 0.315 0.000
O03 Spontaneous abortion
0.685 0.315 0.000
K72 Hepatic failure, not elsewhere classified
0.684 0.316 0.000
D25 Leiomyoma of uterus
0.682 0.318 0.000
I77 Other disorders of arteries and arterioles
0.682 0.318 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.679 0.321 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.679 0.321 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.679 0.321 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.679 0.321 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.679 0.321 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.679 0.321 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.679 0.321 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.679 0.321 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.679 0.321 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.679 0.321 0.000
T36 Poisoning by systemic antibiotics
0.679 0.321 0.000
D55-D59 Haemolytic anaemias
0.679 0.321 0.000
I71 Aortic aneurysm and dissection
0.679 0.321 0.000
K75 Other inflammatory liver diseases
0.678 0.322 0.000
B37.8 Candidiasis of other sites
0.678 0.322 0.000
J41 Simple and mucopurulent chronic bronchitis
0.678 0.322 0.000
R27 Other lack of coordination
0.677 0.323 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.677 0.323 0.000
T43.2 Other and unspecified antidepressants
0.676 0.324 0.000
F60 Specific personality disorders
0.675 0.325 0.000
D22.7 Melanocytic naevi of lower limb, including hip
0.675 0.325 0.000
D22.1 Melanocytic naevi of eyelid, including canthus
0.675 0.325 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.675 0.325 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.675 0.325 0.000
K59.0 Constipation
0.675 0.325 0.000
B48 Other mycoses, not elsewhere classified
0.674 0.326 0.000
B47 Mycetoma
0.674 0.326 0.000
B46 Zygomycosis
0.674 0.326 0.000
B45 Cryptococcosis
0.674 0.326 0.000
B44 Aspergillosis
0.674 0.326 0.000
B43 Chromomycosis and phaeomycotic abscess
0.674 0.326 0.000
B42 Sporotrichosis
0.674 0.326 0.000
B41 Paracoccidioidomycosis
0.674 0.326 0.000
B40 Blastomycosis
0.674 0.326 0.000
B39 Histoplasmosis
0.674 0.326 0.000
B38 Coccidioidomycosis
0.674 0.326 0.000
B36 Other superficial mycoses
0.674 0.326 0.000
B49 Unspecified mycosis
0.674 0.326 0.000
C85.1 B-cell lymphoma, unspecified
0.674 0.326 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.673 0.327 0.000
W00-W19 Falls
0.673 0.327 0.000
I25.2 Old myocardial infarction
0.673 0.327 0.000
M47.8 Other spondylosis
0.672 0.328 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.670 0.329 0.000
A49 Bacterial infection of unspecified site
0.670 0.329 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.670 0.330 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.669 0.330 0.000
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck
0.669 0.331 0.000
D73 Diseases of spleen
0.669 0.331 0.000
D04 Carcinoma in situ of skin
0.669 0.331 0.000
D75.1 Secondary polycythaemia
0.669 0.331 0.000
H90-H95 Other disorders of ear
0.669 0.331 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.668 0.331 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.668 0.332 0.000
O85-O92 Complications predominantly related to the puerperium
0.668 0.332 0.000
J32 Chronic sinusitis
0.668 0.332 0.000
D09 Carcinoma in situ of other and unspecified sites
0.668 0.332 0.000
D23.9 Skin, unspecified
0.668 0.332 0.000
D23.2 Skin of ear and external auricular canal
0.668 0.332 0.000
D23.0 Skin of lip
0.668 0.332 0.000
E50-E64 Other nutritional deficiencies
0.667 0.333 0.000
F31.9 Bipolar affective disorder, unspecified
0.667 0.333 0.000
N10-N16 Renal tubulo-interstitial diseases
0.667 0.333 0.000
L10-L14 Bullous disorders
0.665 0.334 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.665 0.335 0.000
R18 Ascites
0.665 0.335 0.000
L03 Cellulitis
0.664 0.336 0.000
I20.1 Angina pectoris with documented spasm
0.663 0.337 0.000
J42 Unspecified chronic bronchitis
0.663 0.337 0.000
R74 Abnormal serum enzyme levels
0.662 0.338 0.000
X60-X84 Intentional self-harm
0.662 0.338 0.000
D11.0 Parotid gland
0.661 0.339 0.000
D23.1 Skin of eyelid, including canthus
0.661 0.339 0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level
0.660 0.340 0.000
D34 Benign neoplasm of thyroid gland
0.660 0.340 0.000
B37.7 Candidal septicaemia
0.659 0.340 0.000
B37.6 Candidal endocarditis
0.659 0.340 0.000
B37.5 Candidal meningitis
0.659 0.340 0.000
B37.4 Candidiasis of other urogenital sites
0.659 0.340 0.000
B37.2 Candidiasis of skin and nail
0.659 0.340 0.000
B37.1 Pulmonary candidiasis
0.659 0.340 0.000
K57.3 Diverticular disease of large intestine without perforation or abscess
0.659 0.341 0.000
R26.2 Difficulty in walking, not elsewhere classified
0.659 0.341 0.000
R26.1 Paralytic gait
0.659 0.341 0.000
R26.0 Ataxic gait
0.659 0.341 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.659 0.341 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.658 0.342 0.000
S08 Traumatic amputation of part of head
0.658 0.342 0.000
S07 Crushing injury of head
0.658 0.342 0.000
S05 Injury of eye and orbit
0.658 0.342 0.000
S04 Injury of cranial nerves
0.658 0.342 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.658 0.342 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.658 0.342 0.000
D74 Methaemoglobinaemia
0.658 0.342 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.658 0.342 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.658 0.342 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.658 0.342 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.658 0.342 0.000
R77 Other abnormalities of plasma proteins
0.658 0.342 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.658 0.342 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.658 0.342 0.000
R71 Abnormality of red blood cells
0.658 0.342 0.000
C34.0 Main bronchus
0.657 0.343 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.656 0.343 0.000
Y35-Y36 Legal intervention and operations of war
0.656 0.343 0.000
Y10-Y34 Event of undetermined intent
0.656 0.343 0.000
Y00-Y09 Assault
0.656 0.343 0.000
X85-X99 Assault
0.656 0.343 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.656 0.343 0.000
X50-X57 Overexertion, travel and privation
0.656 0.343 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.656 0.343 0.000
X30-X39 Exposure to forces of nature
0.656 0.343 0.000
X20-X29 Contact with venomous animals and plants
0.656 0.343 0.000
X10-X19 Contact with heat and hot substances
0.656 0.343 0.000
X00-X09 Exposure to smoke, fire and flames
0.656 0.343 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.656 0.343 0.000
W75-W84 Other accidental threats to breathing
0.656 0.343 0.000
W65-W74 Accidental drowning and submersion
0.656 0.343 0.000
W50-W64 Exposure to animate mechanical forces
0.656 0.343 0.000
V98-V99 Other and unspecified transport accidents
0.656 0.343 0.000
V95-V97 Air and space transport accidents
0.656 0.343 0.000
V90-V94 Water transport accidents
0.656 0.343 0.000
V80-V89 Other land transport accidents
0.656 0.343 0.000
V70-V79 Bus occupant injured in transport accident
0.656 0.343 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.656 0.343 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.656 0.343 0.000
V40-V49 Car occupant injured in transport accident
0.656 0.343 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.656 0.343 0.000
V20-V29 Motorcycle rider injured in transport accident
0.656 0.343 0.000
V01-V09 Pedestrian injured in transport accident
0.656 0.343 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.656 0.344 0.000
J36 Peritonsillar abscess
0.656 0.344 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.656 0.344 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.656 0.344 0.000
C80 Malignant neoplasm without specification of site
0.655 0.345 0.000
R49 Voice disturbances
0.655 0.345 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.655 0.345 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.655 0.345 0.000
Y95 Nosocomial condition
0.654 0.346 0.000
F41.8 Other specified anxiety disorders
0.653 0.347 0.000
F41.3 Other mixed anxiety disorders
0.653 0.347 0.000
F40.2 Specific (isolated) phobias
0.653 0.347 0.000
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess
0.652 0.348 0.000
K57.5 Diverticular disease of both small and large intestine without perforation or abscess
0.652 0.348 0.000
K57.4 Diverticular disease of both small and large intestine with perforation and abscess
0.652 0.348 0.000
K57.0 Diverticular disease of small intestine with perforation and abscess
0.652 0.348 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.652 0.348 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.651 0.349 0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.651 0.349 0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck
0.650 0.350 0.000
K70.9 Alcoholic liver disease, unspecified
0.650 0.350 0.000
S01.1 Open wound of eyelid and periocular area
0.650 0.350 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.649 0.351 0.000
Chapter VI Diseases of the nervous system
0.649 0.351 0.000
R47.0 Dysphasia and aphasia
0.647 0.353 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.646 0.354 0.000
D18.0 Haemangioma, any site
0.646 0.354 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.646 0.354 0.000
F22 Persistent delusional disorders
0.646 0.354 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.644 0.355 0.000
E87.7 Fluid overload
0.644 0.356 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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