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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs11257655
log Bayes Factor = 4.88826
Chromosome 10   position 12,307,894  (GRCh37) Explore rs11257655 on Ensembl!
Variant rs11257655 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E11 Non-insulin-dependent diabetes mellitus
1.000 0.000 0.000
E11.9 Without complications
1.000 0.000 0.000
E11.4 With neurological complications
0.998 0.002 0.000
E10-E14 Diabetes mellitus
0.990 0.010 0.000
E10 Insulin-dependent diabetes mellitus
0.988 0.012 0.000
E10.9 Without complications
0.985 0.015 0.000
E11.3 With ophthalmic complications
0.970 0.030 0.000
E11.5 With peripheral circulatory complications
0.835 0.165 0.000
E10.3 With ophthalmic complications
0.812 0.188 0.000
E10.1 With ketoacidosis
0.806 0.194 0.000
E11.2 With renal complications
0.793 0.207 0.000
E14 Unspecified diabetes mellitus
0.777 0.223 0.000
E11.0 With coma
0.774 0.226 0.000
E11.8 With unspecified complications
0.771 0.229 0.000
E10.8 With unspecified complications
0.768 0.232 0.000
E10.5 With peripheral circulatory complications
0.764 0.236 0.000
E10.0 With coma
0.724 0.276 0.000
E11.6 With other specified complications
0.719 0.281 0.000
E11.7 With multiple complications
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.710 0.290 0.000
E10.7 With multiple complications
0.708 0.292 0.000
E10.2 With renal complications
0.681 0.319 0.000
E13 Other specified diabetes mellitus
0.677 0.323 0.000
E14.3 With ophthalmic complications
0.658 0.342 0.000
E10.4 With neurological complications
0.632 0.368 0.000
E14.8 With unspecified complications
0.583 0.417 0.000
E10.6 With other specified complications
0.581 0.419 0.000
E14.2 Withrenal complications
0.577 0.423 0.000
E14.4 With neurological complications
0.567 0.433 0.000
E11.1 With ketoacidosis
0.566 0.434 0.000
E14.7 With multiple complications
0.557 0.443 0.000
E14.6 With other specified complications
0.557 0.443 0.000
E14.0 With coma
0.557 0.443 0.000
E14.9 Without complications
0.535 0.465 0.000
E14.5 With peripheral circulatory complications
0.532 0.468 0.000
E13.3 With ophthalmic complications
0.517 0.483 0.000
E12.9 Without complications
0.509 0.491 0.000
E12.8 With unspecified complications
0.509 0.491 0.000
E12.7 With multiple complications
0.509 0.491 0.000
E12.6 With other specified complications
0.509 0.491 0.000
E12.5 With peripheral circulatory complications
0.509 0.491 0.000
E12.4 With neurological complications
0.509 0.491 0.000
E12.3 With ophthalmic complications
0.509 0.491 0.000
E12.2 With renal complications
0.509 0.491 0.000
E12.1 With ketoacidosis
0.509 0.491 0.000
E12.0 With coma
0.509 0.491 0.000
E13.8 With unspecified complications
0.485 0.514 0.000
E13.7 With multiple complications
0.485 0.514 0.000
E13.6 With other specified complications
0.485 0.514 0.000
E13.5 With peripheral circulatory complications
0.485 0.514 0.000
E13.4 With neurological complications
0.485 0.514 0.000
E13.2 With renal complications
0.485 0.514 0.000
E13.1 With ketoacidosis
0.485 0.514 0.000
E13.0 With coma
0.485 0.514 0.000
E14.1 With ketoacidosis
0.478 0.521 0.000
E13.9 Without complications
0.408 0.591 0.000
I25.1 Atherosclerotic heart disease
0.229 0.771 0.000
Z95.1 Presence of aortocoronary bypass graft
0.207 0.793 0.000
I25 Chronic ischaemic heart disease
0.165 0.835 0.000
I27 Other pulmonary heart diseases
0.162 0.838 0.000
I27.2 Other secondary pulmonary hypertension
0.159 0.841 0.000
I20-I25 Ischaemic heart diseases
0.156 0.844 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.151 0.849 0.000
I27.8 Other specified pulmonary heart diseases
0.150 0.850 0.000
I27.9 Pulmonary heart disease, unspecified
0.144 0.855 0.000
Chapter IX Diseases of the circulatory system
0.143 0.857 0.000
I22 Subsequent myocardial infarction
0.139 0.861 0.000
I30-I52 Other forms of heart disease
0.139 0.861 0.000
I25.4 Coronary artery aneurysm
0.139 0.861 0.000
I05-I09 Chronic rheumatic heart diseases
0.137 0.863 0.000
I33 Acute and subacute endocarditis
0.136 0.864 0.000
I33.0 Acute and subacute infective endocarditis
0.136 0.864 0.000
I50.0 Congestive heart failure
0.135 0.865 0.000
I51 Complications and ill-defined descriptions of heart disease
0.134 0.866 0.000
I50 Heart failure
0.134 0.866 0.000
I25.3 Aneurysm of heart
0.132 0.868 0.000
I51.7 Cardiomegaly
0.132 0.868 0.000
I24 Other acute ischaemic heart diseases
0.132 0.868 0.000
I28 Other diseases of pulmonary vessels
0.131 0.869 0.000
I08 Multiple valve diseases
0.128 0.872 0.000
I25.5 Ischaemic cardiomyopathy
0.127 0.873 0.000
I21 Acute myocardial infarction
0.124 0.876 0.000
I38 Endocarditis, valve unspecified
0.124 0.876 0.000
I07 Rheumatic tricuspid valve diseases
0.122 0.877 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.122 0.878 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.122 0.878 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.121 0.879 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.121 0.879 0.000
I35 Nonrheumatic aortic valve disorders
0.119 0.881 0.000
I25.6 Silent myocardial ischaemia
0.118 0.882 0.000
I27.1 Kyphoscoliotic heart disease
0.116 0.884 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.116 0.884 0.000
I28.8 Other specified diseases of pulmonary vessels
0.116 0.884 0.000
I23 Certain current complications following acute myocardial infarction
0.113 0.887 0.000
I06 Rheumatic aortic valve diseases
0.113 0.887 0.000
I27.0 Primary pulmonary hypertension
0.113 0.887 0.000
I35.9 Aortic valve disorder, unspecified
0.112 0.888 0.000
I30 Acute pericarditis
0.112 0.888 0.000
I07.1 Tricuspid insufficiency
0.112 0.888 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.110 0.890 0.000
I51.9 Heart disease, unspecified
0.110 0.890 0.000
I51.8 Other ill-defined heart diseases
0.109 0.891 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.108 0.892 0.000
I21.4 Acute subendocardial myocardial infarction
0.106 0.894 0.000
I21.9 Acute myocardial infarction, unspecified
0.106 0.894 0.000
I22.8 Subsequent myocardial infarction of other sites
0.105 0.895 0.000
I35.8 Other aortic valve disorders
0.104 0.896 0.000
I51.4 Myocarditis, unspecified
0.103 0.897 0.000
I37 Pulmonary valve disorders
0.102 0.898 0.000
I08.9 Multiple valve disease, unspecified
0.100 0.900 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.100 0.900 0.000
I00-I02 Acute rheumatic fever
0.100 0.900 0.000
I52 Other heart disorders in diseases classified elsewhere
0.100 0.900 0.000
I48 Atrial fibrillation and flutter
0.100 0.900 0.000
I41 Myocarditis in diseases classified elsewhere
0.100 0.900 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.100 0.900 0.000
I32 Pericarditis in diseases classified elsewhere
0.100 0.900 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.098 0.902 0.000
I24.1 Dressler's syndrome
0.097 0.902 0.000
I30.9 Acute pericarditis, unspecified
0.097 0.903 0.000
I50.1 Left ventricular failure
0.097 0.903 0.000
I51.5 Myocardial degeneration
0.096 0.903 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.096 0.903 0.000
I36 Nonrheumatic tricuspid valve disorders
0.096 0.904 0.000
I51.6 Cardiovascular disease, unspecified
0.096 0.904 0.000
I33.9 Acute endocarditis, unspecified
0.096 0.904 0.000
I06.0 Rheumatic aortic stenosis
0.096 0.904 0.000
I47 Paroxysmal tachycardia
0.094 0.906 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.094 0.906 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.094 0.906 0.000
I40 Acute myocarditis
0.094 0.906 0.000
I28.9 Disease of pulmonary vessels, unspecified
0.094 0.906 0.000
I28.1 Aneurysm of pulmonary artery
0.094 0.906 0.000
I28.0 Arteriovenous fistula of pulmonary vessels
0.094 0.906 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.093 0.907 0.000
I43.1 Cardiomyopathy in metabolic diseases
0.090 0.910 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.089 0.911 0.000
I47.2 Ventricular tachycardia
0.089 0.911 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.089 0.911 0.000
I07.9 Tricuspid valve disease, unspecified
0.088 0.912 0.000
I07.8 Other tricuspid valve diseases
0.088 0.912 0.000
I07.2 Tricuspid stenosis with insufficiency
0.088 0.912 0.000
I07.0 Tricuspid stenosis
0.088 0.912 0.000
I45 Other conduction disorders
0.086 0.914 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.085 0.915 0.000
I09 Other rheumatic heart diseases
0.084 0.915 0.000
I10-I15 Hypertensive diseases
0.083 0.917 0.000
I23.8 Other current complications following acute myocardial infarction
0.082 0.917 0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.081 0.918 0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.081 0.918 0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.081 0.918 0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.081 0.918 0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.081 0.918 0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.081 0.918 0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.081 0.918 0.000
I06.9 Rheumatic aortic valve disease, unspecified
0.081 0.919 0.000
I06.8 Other rheumatic aortic valve diseases
0.081 0.919 0.000
I06.2 Rheumatic aortic stenosis with insufficiency
0.081 0.919 0.000
I06.1 Rheumatic aortic insufficiency
0.081 0.919 0.000
I30.8 Other forms of acute pericarditis
0.081 0.919 0.000
I30.0 Acute nonspecific idiopathic pericarditis
0.081 0.919 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.079 0.920 0.000
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.079 0.921 0.000
I43.2 Cardiomyopathy in nutritional diseases
0.079 0.921 0.000
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.079 0.921 0.000
I15 Secondary hypertension
0.078 0.922 0.000
I37.1 Pulmonary valve insufficiency
0.076 0.924 0.000
I05 Rheumatic mitral valve diseases
0.075 0.925 0.000
I45.4 Nonspecific intraventricular block
0.074 0.926 0.000
I37.9 Pulmonary valve disorder, unspecified
0.073 0.926 0.000
I37.8 Other pulmonary valve disorders
0.073 0.926 0.000
I37.2 Pulmonary valve stenosis with insufficiency
0.073 0.926 0.000
I37.0 Pulmonary valve stenosis
0.073 0.926 0.000
I45.9 Conduction disorder, unspecified
0.073 0.927 0.000
I15.1 Hypertension secondary to other renal disorders
0.073 0.927 0.000
I42 Cardiomyopathy
0.073 0.927 0.000
I30.1 Infective pericarditis
0.072 0.927 0.000
I02 Rheumatic chorea
0.072 0.928 0.000
I01 Rheumatic fever with heart involvement
0.072 0.928 0.000
I32.8 Pericarditis in other diseases classified elsewhere
0.072 0.928 0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.072 0.928 0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.072 0.928 0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.072 0.928 0.000
I39.4 Multiple valve disorders in diseases classified elsewhere
0.072 0.928 0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.072 0.928 0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.072 0.928 0.000
I39.1 Aortic valve disorders in diseases classified elsewhere
0.072 0.928 0.000
I39.0 Mitral valve disorders in diseases classified elsewhere
0.072 0.928 0.000
I41.8 Myocarditis in other diseases classified elsewhere
0.072 0.928 0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.072 0.928 0.000
I41.1 Myocarditis in viral diseases classified elsewhere
0.072 0.928 0.000
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.072 0.928 0.000
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.072 0.928 0.000
I48.4 Atypical atrial flutter
0.072 0.928 0.000
I48.3 Typical atrial flutter
0.072 0.928 0.000
I48.2 Chronic atrial fibrillation
0.072 0.928 0.000
I48.1 Persistent atrial fibrillation
0.072 0.928 0.000
I48.0 Paroxysmal atrial fibrillation
0.072 0.928 0.000
I52.8 Other heart disorders in other diseases classified elsewhere
0.072 0.928 0.000
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.072 0.928 0.000
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.072 0.928 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.071 0.929 0.000
I51.0 Cardiac septal defect, acquired
0.070 0.929 0.000
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.069 0.931 0.000
I36.8 Other nonrheumatic tricuspid valve disorders
0.069 0.931 0.000
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.069 0.931 0.000
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.069 0.931 0.000
I00 Rheumatic fever without mention of heart involvement
0.069 0.931 0.000
I26 Pulmonary embolism
0.068 0.932 0.000
I40.9 Acute myocarditis, unspecified
0.067 0.932 0.000
I40.8 Other acute myocarditis
0.067 0.932 0.000
I40.1 Isolated myocarditis
0.067 0.932 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.068 0.932 0.000
I45.0 Right fascicular block
0.067 0.933 0.000
I47.0 Reentry ventricular arrhythmia
0.067 0.933 0.000
I46 Cardiac arrest
0.067 0.933 0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.065 0.935 0.000
I15.8 Other secondary hypertension
0.065 0.935 0.000
I45.3 Trifascicular block
0.065 0.935 0.000
I42.9 Cardiomyopathy, unspecified
0.064 0.936 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.064 0.936 0.000
I35.0 Aortic (valve) stenosis
0.062 0.938 0.000
I40.0 Infective myocarditis
0.062 0.938 0.000
I09.8 Other specified rheumatic heart diseases
0.061 0.939 0.000
I09.2 Chronic rheumatic pericarditis
0.061 0.939 0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.061 0.939 0.000
I09.0 Rheumatic myocarditis
0.061 0.939 0.000
I13 Hypertensive heart and renal disease
0.059 0.940 0.000
I11 Hypertensive heart disease
0.057 0.943 0.000
I15.2 Hypertension secondary to endocrine disorders
0.056 0.944 0.000
I15.0 Renovascular hypertension
0.056 0.944 0.000
I05.9 Mitral valve disease, unspecified
0.056 0.944 0.000
I45.6 Preexcitation syndrome
0.054 0.946 0.000
I05.8 Other mitral valve diseases
0.054 0.946 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.054 0.946 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.053 0.947 0.000
I08.8 Other multiple valve diseases
0.053 0.947 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.053 0.947 0.000
I42.5 Other restrictive cardiomyopathy
0.052 0.947 0.000
I42.4 Endocardial fibroelastosis
0.052 0.947 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.052 0.947 0.000
I42.6 Alcoholic cardiomyopathy
0.052 0.948 0.000
I15.9 Seconday hypertension, unspecified
0.052 0.948 0.000
I24.8 Other forms of acute ischaemic heart disease
0.052 0.948 0.000
I01.9 Acute rheumatic heart disease, unspecified
0.052 0.948 0.000
I01.8 Other acute rheumatic heart disease
0.052 0.948 0.000
I01.2 Acute rheumatic myocarditis
0.052 0.948 0.000
I01.1 Acute rheumatic endocarditis
0.052 0.948 0.000
I01.0 Acute rheumatic pericarditis
0.052 0.948 0.000
I02.9 Rheumatic chorea without heart involvement
0.052 0.948 0.000
I02.0 Rheumatic chorea with heart involvement
0.052 0.948 0.000
I45.5 Other specified heart block
0.052 0.948 0.000
I45.2 Bifascicular block
0.051 0.949 0.000
I45.8 Other specified conduction disorders
0.051 0.949 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.051 0.949 0.000
I42.0 Dilated cardiomyopathy
0.050 0.950 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.050 0.950 0.000
I05.0 Mitral stenosis
0.049 0.951 0.000
I50.9 Heart failure, unspecified
0.049 0.951 0.000
I05.2 Mitral stenosis with insufficiency
0.048 0.952 0.000
I46.1 Sudden cardiac death, so described
0.048 0.952 0.000
I46.0 Cardiac arrest with successful resuscitation
0.047 0.953 0.000
I09.9 Rheumatic heart disease, unspecified
0.047 0.953 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.045 0.955 0.000
I05.1 Rheumatic mitral insufficiency
0.045 0.955 0.000
I11.0 Hypertensive heart disease with (congestive) heart failure
0.044 0.956 0.000
I13.9 Hypertensive heart and renal disease, unspecified
0.043 0.957 0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.043 0.957 0.000
I13.1 Hypertensive heart and renal disease with renal failure
0.043 0.957 0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.043 0.957 0.000
I42.2 Other hypertrophic cardiomyopathy
0.043 0.957 0.000
I08.0 Disorders of both mitral and aortic valves
0.042 0.958 0.000
I45.1 Other and unspecified right bundle-branch block
0.040 0.960 0.000
I31 Other diseases of pericardium
0.040 0.960 0.000
I99 Other and unspecified disorders of circulatory system
0.040 0.960 0.000
I35.1 Aortic (valve) insufficiency
0.039 0.961 0.000
I42.8 Other cardiomyopathies
0.037 0.962 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.037 0.963 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.037 0.963 0.000
C79 Secondary malignant neoplasm of other sites
0.036 0.964 0.000
I11.9 Hypertensive heart disease without (congestive) heart failure
0.034 0.965 0.000
I12 Hypertensive renal disease
0.034 0.966 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.032 0.967 0.000
I31.1 Chronic constrictive pericarditis
0.031 0.969 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.030 0.970 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.030 0.970 0.000
I31.8 Other specified diseases of pericardium
0.029 0.971 0.000
I31.2 Haemopericardium, not elsewhere classified
0.029 0.971 0.000
I97.1 Other functional disturbances following cardiac surgery
0.028 0.971 0.000
I97.2 Postmastectomy lymphoedema syndrome
0.028 0.972 0.000
C79.6 Secondary malignant neoplasm of ovary
0.028 0.972 0.000
I31.0 Chronic adhesive pericarditis
0.028 0.972 0.000
I97.9 Postprocedural disorder of circulatory system, unspecified
0.027 0.973 0.000
I97.0 Postcardiotomy syndrome
0.027 0.973 0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.023 0.977 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.023 0.977 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.023 0.977 0.000
I34 Nonrheumatic mitral valve disorders
0.022 0.977 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.021 0.979 0.000
I20 Angina pectoris
0.021 0.979 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.020 0.980 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.019 0.981 0.000
E21.0 Primary hyperparathyroidism
0.019 0.981 0.000
I47.1 Supraventricular tachycardia
0.018 0.982 0.000
E21.3 Hyperparathyroidism, unspecified
0.018 0.982 0.000
C80 Malignant neoplasm without specification of site
0.018 0.982 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.018 0.982 0.000
C80.9 Malignant neoplasm, unspecified
0.018 0.982 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.017 0.983 0.000
E34 Other endocrine disorders
0.017 0.983 0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.016 0.983 0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.016 0.983 0.000
I98.0 Cardiovascular syphilis
0.016 0.983 0.000
E20-E35 Disorders of other endocrine glands
0.017 0.983 0.000
I12.9 Hypertensive renal disease without renal failure
0.017 0.983 0.000
I46.9 Cardiac arrest, unspecified
0.016 0.984 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.016 0.984 0.000
C79.2 Secondary malignant neoplasm of skin
0.016 0.984 0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.016 0.984 0.000
G59.0 Diabetic mononeuropathy
0.016 0.984 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.015 0.985 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.015 0.985 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.015 0.985 0.000
I12.0 Hypertensive renal disease with renal failure
0.015 0.985 0.000
E34.0 Carcinoid syndrome
0.015 0.985 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.015 0.985 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.014 0.986 0.000
I31.3 Pericardial effusion (noninflammatory)
0.014 0.986 0.000
I20.1 Angina pectoris with documented spasm
0.014 0.986 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.014 0.986 0.000
E34.9 Endocrine disorder, unspecified
0.014 0.986 0.000
E34.8 Other specified endocrine disorders
0.014 0.986 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.014 0.986 0.000
E21.4 Other specified disorders of parathyroid gland
0.014 0.986 0.000
E21.2 Other hyperparathyroidism
0.014 0.986 0.000
E34.3 Short stature, not elsewhere classified
0.014 0.986 0.000
E65-E68 Obesity and other hyperalimentation
0.014 0.986 0.000
Z95.4 Presence of other heart-valve replacement
0.014 0.986 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.013 0.987 0.000
E40-E46 Malnutrition
0.013 0.987 0.000
J35.0 Chronic tonsillitis
0.000 0.987 0.013
E20 Hypoparathyroidism
0.012 0.988 0.000
E34.5 Androgen resistance syndrome
0.012 0.988 0.000
E34.4 Constitutional tall stature
0.012 0.988 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.012 0.988 0.000
E34.1 Other hypersecretion of intestinal hormones
0.012 0.988 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.012 0.988 0.000
E32 Diseases of thymus
0.012 0.988 0.000
E31 Polyglandular dysfunction
0.012 0.988 0.000
E30 Disorders of puberty, not elsewhere classified
0.012 0.988 0.000
E25 Adrenogenital disorders
0.012 0.988 0.000
E65 Localised adiposity
0.012 0.988 0.000
C76.0 Head, face and neck
0.012 0.988 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.012 0.988 0.000
I20.8 Other forms of angina pectoris
0.011 0.989 0.000
Z95.3 Presence of xenogenic heart valve
0.011 0.989 0.000
E26 Hyperaldosteronism
0.011 0.989 0.000
E24 Cushing's syndrome
0.011 0.989 0.000
E29 Testicular dysfunction
0.011 0.989 0.000
C76.8 Overlapping lesion of other and ill-defined sites
0.010 0.990 0.000
C76.7 Other ill-defined sites
0.010 0.990 0.000
C76.5 Lower limb
0.010 0.990 0.000
C76.4 Upper limb
0.010 0.990 0.000
C76.2 Abdomen
0.010 0.990 0.000
C76.1 Thorax
0.010 0.990 0.000
E67 Other hyperalimentation
0.010 0.990 0.000
E68 Sequelae of hyperalimentation
0.010 0.990 0.000
Z95.0 Presence of cardiac pacemaker
0.010 0.990 0.000
C76.3 Pelvis
0.010 0.990 0.000
E28 Ovarian dysfunction
0.010 0.990 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.009 0.990 0.000
E45 Retarded development following protein-energy malnutrition
0.009 0.990 0.000
E43 Unspecified severe protein-energy malnutrition
0.009 0.990 0.000
E42 Marasmic kwashiorkor
0.009 0.990 0.000
E41 Nutritional marasmus
0.009 0.990 0.000
E40 Kwashiorkor
0.009 0.990 0.000
I25.2 Old myocardial infarction
0.009 0.991 0.000
E20.9 Hypoparathyroidism, unspecified
0.009 0.991 0.000
E20.8 Other hypoparathyroidism
0.009 0.991 0.000
E20.1 Pseudohypoparathyroidism
0.009 0.991 0.000
E20.0 Idiopathic hypoparathyroidism
0.009 0.991 0.000
E25.9 Adrenogenital disorder, unspecified
0.009 0.991 0.000
E25.8 Other adrenogenital disorders
0.009 0.991 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.009 0.991 0.000
E30.9 Disorder of puberty, unspecified
0.009 0.991 0.000
E30.8 Other disorders of puberty
0.009 0.991 0.000
E30.1 Precocious puberty
0.009 0.991 0.000
E30.0 Delayed puberty
0.009 0.991 0.000
E31.9 Polyglandular dysfunction, unspecified
0.009 0.991 0.000
E31.8 Other polyglandular dysfunction
0.009 0.991 0.000
E31.1 Polyglandular hyperfunction
0.009 0.991 0.000
E31.0 Autoimmune polyglandular failure
0.009 0.991 0.000
E32.9 Disease of thymus, unspecified
0.009 0.991 0.000
E32.8 Other diseases of thymus
0.009 0.991 0.000
E32.1 Abscess of thymus
0.009 0.991 0.000
E32.0 Persistent hyperplasia of thymus
0.009 0.991 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.009 0.991 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.009 0.991 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.009 0.991 0.000
E24.2 Drug-induced Cushing's syndrome
0.009 0.991 0.000
E15 Nondiabetic hypoglycaemic coma
0.009 0.991 0.000
H36.0 Diabetic retinopathy
0.009 0.991 0.000
E50-E64 Other nutritional deficiencies
0.008 0.992 0.000
E26.9 Hyperaldosteronism, unspecified
0.008 0.992 0.000
E26.8 Other hyperaldosteronism
0.008 0.992 0.000
E26.1 Secondary hyperaldosteronism
0.008 0.992 0.000
I44 Atrioventricular and left bundle-branch block
0.008 0.992 0.000
E24.8 Other Cushing's syndrome
0.008 0.992 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.008 0.992 0.000
E24.3 Ectopic ACTH syndrome
0.008 0.992 0.000
E24.1 Nelson's syndrome
0.008 0.992 0.000
E29.9 Testicular dysfunction, unspecified
0.008 0.992 0.000
E29.8 Other testicular dysfunction
0.008 0.992 0.000
E29.0 Testicular hyperfunction
0.008 0.992 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.008 0.992 0.000
E67.8 Other specified hyperalimentation
0.007 0.992 0.000
E67.3 Hypervitaminosis D
0.007 0.992 0.000
E67.2 Megavitamin-B6 syndrome
0.007 0.992 0.000
E67.1 Hypercarotenaemia
0.007 0.992 0.000
E67.0 Hypervitaminosis A
0.007 0.992 0.000
E46 Unspecified protein-energy malnutrition
0.007 0.993 0.000
I49 Other cardiac arrhythmias
0.007 0.993 0.000
Y83.4 Other reconstructive surgery
0.000 0.993 0.007
E28.9 Ovarian dysfunction, unspecified
0.007 0.993 0.000
E28.8 Other ovarian dysfunction
0.007 0.993 0.000
E28.1 Androgen excess
0.007 0.993 0.000
E28.0 Oestrogen excess
0.007 0.993 0.000
E44.1 Mild protein-energy malnutrition
0.007 0.993 0.000
E44.0 Moderate protein-energy malnutrition
0.007 0.993 0.000
I61 Intracerebral haemorrhage
0.007 0.993 0.000
E24.0 Pituitary-dependent Cushing's disease
0.007 0.993 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.007 0.993 0.000
I60-I69 Cerebrovascular diseases
0.007 0.993 0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.007 0.993 0.000
Z57.5 Occupational exposure to toxic agents in other industries
0.007 0.993 0.000
T91.8 Sequelae of other specified injuries of neck and trunk
0.000 0.993 0.007
I31.9 Disease of pericardium, unspecified
0.007 0.993 0.000
E26.0 Primary hyperaldosteronism
0.007 0.993 0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.007 0.993 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.007 0.993 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.007 0.993 0.000
E28.3 Primary ovarian failure
0.006 0.993 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.007 0.993 0.000
I95 Hypotension
0.007 0.993 0.000
T91 Sequelae of injuries of neck and trunk
0.000 0.993 0.007
F41.2 Mixed anxiety and depressive disorder
0.000 0.993 0.007
C77.4 Inguinal and lower limb lymph nodes
0.006 0.994 0.000
M47.86 Other spondylosis (Lumbar region)
0.006 0.994 0.000
E29.1 Testicular hypofunction
0.006 0.994 0.000
T91.2 Sequelae of other fracture of thorax and pelvis
0.000 0.994 0.006
E64 Sequelae of malnutrition and other nutritional deficiencies
0.006 0.994 0.000
E63 Other nutritional deficiencies
0.006 0.994 0.000
E56 Other vitamin deficiencies
0.006 0.994 0.000
E51 Thiamine deficiency
0.006 0.994 0.000
E50 Vitamin A deficiency
0.006 0.994 0.000
E60 Dietary zinc deficiency
0.006 0.994 0.000
E59 Dietary selenium deficiency
0.006 0.994 0.000
E58 Dietary calcium deficiency
0.006 0.994 0.000
E54 Ascorbic acid deficiency
0.006 0.994 0.000
E52 Niacin deficiency [pellagra]
0.006 0.994 0.000
I44.5 Left posterior fascicular block
0.006 0.994 0.000
I44.4 Left anterior fascicular block
0.006 0.994 0.000
E22 Hyperfunction of pituitary gland
0.006 0.994 0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.006 0.994 0.000
T91.3 Sequelae of injury of spinal cord
0.000 0.994 0.006
I44.6 Other and unspecified fascicular block
0.006 0.994 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.005 0.994 0.001
E27 Other disorders of adrenal gland
0.006 0.994 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.006 0.994 0.000
I49.3 Ventricular premature depolarisation
0.006 0.994 0.000
I49.2 Junctional premature depolarisation
0.005 0.994 0.000
Z57 Occupational exposure to risk-factors
0.006 0.994 0.000
E28.2 Polycystic ovarian syndrome
0.005 0.995 0.000
C77.8 Lymph nodes of multiple regions
0.005 0.995 0.000
E24.9 Cushing's syndrome, unspecified
0.005 0.995 0.000
I95.8 Other hypotension
0.005 0.995 0.000
I61.6 Intracerebral haemorrhage, multiple localised
0.005 0.995 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.005 0.995 0.000
C77.0 Lymph nodes of head, face and neck
0.005 0.995 0.000
E55 Vitamin D deficiency
0.005 0.995 0.000
E16 Other disorders of pancreatic internal secretion
0.005 0.995 0.000
I49.4 Other and unspecified premature depolarisation
0.005 0.995 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.005 0.995 0.000
Z03.3 Observation for suspected nervous system disorder
0.005 0.995 0.000
E00-E07 Disorders of thyroid gland
0.005 0.995 0.000
Y45.0 Opioids and related analgesics
0.005 0.995 0.000
I61.4 Intracerebral haemorrhage in cerebellum
0.005 0.995 0.000
G59.8 Other mononeuropathies in diseases classified elsewhere
0.005 0.995 0.000
I49.1 Atrial premature depolarisation
0.005 0.995 0.000
Z57.3 Occupational exposure to other air contaminants
0.005 0.995 0.000
T91.9 Sequelae of unspecified injury of neck and trunk
0.000 0.995 0.005
T91.5 Sequelae of injury of intra-abdominal and pelvic organs
0.000 0.995 0.005
T91.4 Sequelae of injury of intrathoracic organs
0.000 0.995 0.005
T91.0 Sequelae of superficial injury and open wound of neck and trunk
0.000 0.995 0.005
I68 Cerebrovascular disorders in diseases classified elsewhere
0.005 0.995 0.000
C77.1 Intrathoracic lymph nodes
0.005 0.995 0.000
E61 Deficiency of other nutrient elements
0.005 0.995 0.000
C77.5 Intrapelvic lymph nodes
0.005 0.995 0.000
Z57.2 Occupational exposure to dust
0.005 0.995 0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.005 0.995 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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