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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs112767144
log Bayes Factor = 30.2394
Chromosome 8   position 134,263,916  (GRCh37) Explore rs112767144 on Ensembl!
Variant rs112767144 is part of Cluster X0192

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
N17-N19 Renal failure
0.999 0.001 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.998 0.002 0.000
Chapter VI Diseases of the nervous system
0.998 0.002 0.000
Chapter VII Diseases of the eye and adnexa
0.998 0.002 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.997 0.003 0.000
D50-D53 Nutritional anaemias
0.996 0.004 0.000
I60-I69 Cerebrovascular diseases
0.996 0.004 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.995 0.005 0.000
D50 Iron deficiency anaemia
0.995 0.005 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.994 0.006 0.000
F30-F39 Mood [affective] disorders
0.993 0.007 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.991 0.009 0.000
H40-H42 Glaucoma
0.991 0.009 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.990 0.010 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.990 0.010 0.000
N19 Unspecified renal failure
0.988 0.012 0.000
H40 Glaucoma
0.986 0.014 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.986 0.014 0.000
D50.9 Iron deficiency anaemia, unspecified
0.985 0.015 0.000
J09-J18 Influenza and pneumonia
0.985 0.015 0.000
S00-S09 Injuries to the head
0.983 0.017 0.000
S60-S69 Injuries to the wrist and hand
0.981 0.019 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.981 0.019 0.000
F31 Bipolar affective disorder
0.979 0.021 0.000
H40.0 Glaucoma suspect
0.979 0.021 0.000
N94.6 Dysmenorrhoea, unspecified
0.977 0.023 0.000
J40-J47 Chronic lower respiratory diseases
0.976 0.024 0.000
F41 Other anxiety disorders
0.976 0.024 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.976 0.024 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.975 0.025 0.000
Chapter XX External causes of morbidity and mortality
0.975 0.025 0.000
G40-G47 Episodic and paroxysmal disorders
0.974 0.026 0.000
D50.8 Other iron deficiency anaemias
0.974 0.026 0.000
N18 Chronic renal failure
0.972 0.028 0.000
J18 Pneumonia, organism unspecified
0.970 0.030 0.000
E70-E90 Metabolic disorders
0.968 0.032 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.967 0.033 0.000
R79 Other abnormal findings of blood chemistry
0.966 0.034 0.000
I69 Sequelae of cerebrovascular disease
0.965 0.035 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.957 0.043 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.956 0.044 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.954 0.046 0.000
E10-E14 Diabetes mellitus
0.951 0.049 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.950 0.050 0.000
I63 Cerebral infarction
0.947 0.053 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.946 0.054 0.000
S61 Open wound of wrist and hand
0.945 0.055 0.000
R47-R49 Symptoms and signs involving speech and voice
0.943 0.057 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.942 0.058 0.000
S00 Superficial injury of head
0.941 0.059 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.940 0.060 0.000
H04 Disorders of lachrymal system
0.939 0.061 0.000
J95-J99 Other diseases of the respiratory system
0.938 0.062 0.000
J43 Emphysema
0.938 0.062 0.000
J60-J70 Lung diseases due to external agents
0.938 0.062 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.938 0.062 0.000
J18.9 Pneumonia, unspecified
0.935 0.065 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.934 0.066 0.000
Chapter VIII Diseases of the ear and mastoid process
0.929 0.071 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.927 0.073 0.000
N40-N51 Diseases of male genital organs
0.926 0.074 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.925 0.075 0.000
J44 Other chronic obstructive pulmonary disease
0.923 0.077 0.000
G47 Sleep disorders
0.921 0.079 0.000
S80-S89 Injuries to the knee and lower leg
0.920 0.080 0.000
W00-W19 Falls
0.919 0.081 0.000
M70-M79 Other soft tissue disorders
0.915 0.085 0.000
S01 Open wound of head
0.914 0.086 0.000
J43.9 Emphysema, unspecified
0.910 0.090 0.000
F41.9 Anxiety disorder, unspecified
0.910 0.090 0.000
G30-G32 Other degenerative diseases of the nervous system
0.908 0.092 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.907 0.093 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.903 0.097 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.902 0.098 0.000
N97 Female infertility
0.902 0.098 0.000
S00.8 Superficial injury of other parts of head
0.902 0.098 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.899 0.101 0.000
I67 Other cerebrovascular diseases
0.896 0.104 0.000
S64 Injury of nerves at wrist and hand level
0.896 0.104 0.000
G47.9 Sleep disorder, unspecified
0.890 0.110 0.000
F31.9 Bipolar affective disorder, unspecified
0.888 0.112 0.000
J69 Pneumonitis due to solids and liquids
0.885 0.115 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.883 0.117 0.000
H00 Hordeolum and chalazion
0.882 0.118 0.000
E78.0 Pure hypercholesterolaemia
0.880 0.120 0.000
Chapter XXII Codes for special purposes
0.879 0.121 0.000
N94.3 Premenstrual tension syndrome
0.877 0.123 0.000
G81 Hemiplegia
0.874 0.126 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.873 0.127 0.000
H65-H75 Diseases of middle ear and mastoid
0.873 0.127 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.871 0.129 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.870 0.130 0.000
E86 Volume depletion
0.870 0.130 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.869 0.131 0.000
N40 Hyperplasia of prostate
0.868 0.132 0.000
H04.2 Epiphora
0.867 0.133 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.867 0.133 0.000
F10.3 Withdrawal state
0.867 0.133 0.000
F10.2 Dependence syndrome
0.866 0.134 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.866 0.134 0.000
J84 Other interstitial pulmonary diseases
0.866 0.134 0.000
N17 Acute renal failure
0.864 0.136 0.000
N92 Excessive, frequent and irregular menstruation
0.863 0.137 0.000
S61.8 Open wound of other parts of wrist and hand
0.863 0.137 0.000
E14 Unspecified diabetes mellitus
0.861 0.139 0.000
H40.9 Glaucoma, unspecified
0.860 0.140 0.000
R22.9 Localised swelling, mass and lump, unspecified
0.859 0.141 0.000
E10 Insulin-dependent diabetes mellitus
0.858 0.142 0.000
N18.5 Chronic kidney disease, stage 5
0.857 0.143 0.000
R20 Disturbances of skin sensation
0.855 0.145 0.000
J98 Other respiratory disorders
0.853 0.147 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.852 0.148 0.000
R47 Speech disturbances, not elsewhere classified
0.851 0.149 0.000
R22.2 Localised swelling, mass and lump, trunk
0.850 0.149 0.000
G20-G26 Extrapyramidal and movement disorders
0.850 0.150 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.849 0.151 0.000
W19 Unspecified fall
0.849 0.151 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.848 0.152 0.000
J69.0 Pneumonitis due to food and vomit
0.848 0.152 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.847 0.153 0.000
F33 Recurrent depressive disorder
0.847 0.153 0.000
S61.0 Open wound of finger(s) without damage to nail
0.846 0.154 0.000
Chapter I Certain infectious and parasitic diseases
0.843 0.157 0.000
G40 Epilepsy
0.842 0.158 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.840 0.160 0.000
J18.0 Bronchopneumonia, unspecified
0.839 0.161 0.000
F00 Dementia in Alzheimer's disease
0.837 0.163 0.000
G81.9 Hemiplegia, unspecified
0.837 0.163 0.000
I26 Pulmonary embolism
0.837 0.163 0.000
S01.1 Open wound of eyelid and periocular area
0.834 0.166 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.833 0.167 0.000
N18.0 End-stage renal disease
0.831 0.169 0.000
R22.4 Localised swelling, mass and lump, lower limb
0.831 0.169 0.000
N93 Other abnormal uterine and vaginal bleeding
0.830 0.170 0.000
M77 Other enthesopathies
0.828 0.172 0.000
R49 Voice disturbances
0.828 0.172 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.828 0.172 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.827 0.173 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.827 0.173 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.827 0.173 0.000
F25 Schizoaffective disorders
0.826 0.173 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.826 0.174 0.000
F60-F69 Disorders of adult personality and behaviour
0.826 0.174 0.000
S81 Open wound of lower leg
0.825 0.175 0.000
N18.9 Chronic renal failure, unspecified
0.825 0.175 0.000
N97.9 Female infertility, unspecified
0.825 0.175 0.000
E20-E35 Disorders of other endocrine glands
0.824 0.176 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.822 0.178 0.000
R22.3 Localised swelling, mass and lump, upper limb
0.821 0.179 0.000
F43 Reaction to severe stress, and adjustment disorders
0.820 0.180 0.000
N92.1 Excessive and frequent menstruation with irregular cycle
0.820 0.180 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.819 0.181 0.000
N94.8 Other specified conditions associated with female genital organs and menstrual cycle
0.818 0.182 0.000
S10-S19 Injuries to the neck
0.816 0.183 0.000
F41.2 Mixed anxiety and depressive disorder
0.816 0.184 0.000
F99-F99 Unspecified mental disorder
0.816 0.184 0.000
D51 Vitamin B12 deficiency anaemia
0.815 0.185 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.814 0.186 0.000
I05-I09 Chronic rheumatic heart diseases
0.814 0.186 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.814 0.186 0.000
F22 Persistent delusional disorders
0.813 0.187 0.000
M86-M90 Other osteopathies
0.811 0.189 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.810 0.190 0.000
J98.1 Pulmonary collapse
0.810 0.190 0.000
I27 Other pulmonary heart diseases
0.808 0.192 0.000
E14.9 Without complications
0.807 0.193 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.806 0.194 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.805 0.195 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.804 0.196 0.000
H00.1 Chalazion
0.804 0.196 0.000
R79.0 Abnormal level of blood mineral
0.804 0.196 0.000
F32 Depressive episode
0.802 0.198 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.802 0.198 0.000
F03 Unspecified dementia
0.801 0.199 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.801 0.199 0.000
S64.4 Injury of digital nerve of other finger
0.800 0.200 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.799 0.201 0.000
F10.0 Acute intoxication
0.798 0.202 0.000
I63.9 Cerebral infarction, unspecified
0.798 0.202 0.000
F40 Phobic anxiety disorders
0.797 0.203 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.797 0.203 0.000
J18.1 Lobar pneumonia, unspecified
0.796 0.204 0.000
T86 Failure and rejection of transplanted organs and tissues
0.796 0.204 0.000
G30 Alzheimer's disease
0.795 0.205 0.000
J00-J06 Acute upper respiratory infections
0.794 0.206 0.000
N18.4 Chronic kidney disease, stage 4
0.794 0.206 0.000
I10-I15 Hypertensive diseases
0.794 0.206 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.793 0.207 0.000
I69.3 Sequelae of cerebral infarction
0.792 0.208 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.792 0.208 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.790 0.210 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.789 0.211 0.000
H01 Other inflammation of eyelid
0.788 0.212 0.000
S00.0 Superficial injury of scalp
0.788 0.212 0.000
H04.9 Disorder of lachrymal system, unspecified
0.785 0.214 0.000
E50-E64 Other nutritional deficiencies
0.785 0.215 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.784 0.216 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.782 0.218 0.000
I67.2 Cerebral atherosclerosis
0.781 0.219 0.000
J47 Bronchiectasis
0.780 0.220 0.000
I63.8 Other cerebral infarction
0.780 0.220 0.000
D60-D64 Aplastic and other anaemias
0.779 0.221 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.779 0.221 0.000
N41 Inflammatory diseases of prostate
0.779 0.221 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.779 0.221 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.778 0.222 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.778 0.222 0.000
Y95 Nosocomial condition
0.778 0.222 0.000
H53-H54 Visual disturbances and blindness
0.778 0.222 0.000
W19.9 Unspecified place
0.777 0.223 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.775 0.225 0.000
H90-H95 Other disorders of ear
0.774 0.225 0.000
N88 Other noninflammatory disorders of cervix uteri
0.770 0.230 0.000
N00-N08 Glomerular diseases
0.769 0.231 0.000
H04.1 Other disorders of lachrymal gland
0.768 0.232 0.000
G41 Status epilepticus
0.767 0.232 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.767 0.233 0.000
E10.1 With ketoacidosis
0.767 0.233 0.000
M79.0 Rheumatism, unspecified
0.767 0.233 0.000
R22.0 Localised swelling, mass and lump, head
0.766 0.234 0.000
S80 Superficial injury of lower leg
0.765 0.235 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.764 0.236 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.764 0.236 0.000
S90-S99 Injuries to the ankle and foot
0.763 0.236 0.000
M45-M49 Spondylopathies
0.763 0.237 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.762 0.238 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.759 0.241 0.000
F10.4 Withdrawal state with delirium
0.759 0.241 0.000
R21 Rash and other nonspecific skin eruption
0.759 0.241 0.000
N99-N99 Other disorders of the genitourinary system
0.757 0.243 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.756 0.244 0.000
H55-H59 Other disorders of eye and adnexa
0.756 0.244 0.000
J40 Bronchitis, not specified as acute or chronic
0.755 0.244 0.000
N94.1 Dyspareunia
0.755 0.245 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.755 0.245 0.000
H40.2 Primary angle-closure glaucoma
0.754 0.246 0.000
D55-D59 Haemolytic anaemias
0.754 0.246 0.000
F10.1 Harmful use
0.753 0.247 0.000
E83 Disorders of mineral metabolism
0.753 0.247 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.752 0.247 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.753 0.247 0.000
M77.9 Enthesopathy, unspecified
0.752 0.248 0.000
S01.9 Open wound of head, part unspecified
0.751 0.249 0.000
F00.9 Dementia in Alzheimer's disease, unspecified
0.751 0.249 0.000
G90-G99 Other disorders of the nervous system
0.751 0.249 0.000
N82 Fistulae involving female genital tract
0.750 0.249 0.000
S82 Fracture of lower leg, including ankle
0.750 0.250 0.000
N90.4 Leukoplakia of vulva
0.747 0.253 0.000
J81 Pulmonary oedema
0.747 0.253 0.000
R47.0 Dysphasia and aphasia
0.746 0.254 0.000
R49.0 Dysphonia
0.746 0.254 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.746 0.254 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.746 0.254 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.745 0.255 0.000
T87 Complications peculiar to reattachment and amputation
0.745 0.255 0.000
H10-H13 Disorders of conjunctiva
0.745 0.255 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.745 0.255 0.000
W06 Fall involving bed
0.744 0.255 0.000
F25.9 Schizoaffective disorder, unspecified
0.744 0.256 0.000
F20 Schizophrenia
0.743 0.257 0.000
J10 Influenza due to identified influenza virus
0.743 0.257 0.000
R22.1 Localised swelling, mass and lump, neck
0.742 0.258 0.000
E65-E68 Obesity and other hyperalimentation
0.742 0.258 0.000
R29.6 Tendency to fall, not elsewhere classified
0.741 0.259 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.739 0.261 0.000
I67.8 Other specified cerebrovascular diseases
0.739 0.261 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.737 0.263 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.737 0.263 0.000
S64.3 Injury of digital nerve of thumb
0.737 0.263 0.000
S05 Injury of eye and orbit
0.737 0.263 0.000
M40-M43 Deforming dorsopathies
0.736 0.264 0.000
H65 Nonsuppurative otitis media
0.736 0.264 0.000
N17.9 Acute renal failure, unspecified
0.736 0.264 0.000
N75 Diseases of Bartholin's gland
0.735 0.265 0.000
F05.9 Delirium, unspecified
0.734 0.266 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.734 0.266 0.000
V80-V89 Other land transport accidents
0.730 0.270 0.000
M79.8 Other specified soft tissue disorders
0.730 0.270 0.000
M80-M85 Disorders of bone density and structure
0.729 0.270 0.000
N80 Endometriosis
0.729 0.271 0.000
R23 Other skin changes
0.729 0.271 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.729 0.271 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.729 0.271 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.729 0.271 0.000
H72 Perforation of tympanic membrane
0.729 0.271 0.000
R41.0 Disorientation, unspecified
0.728 0.272 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.728 0.272 0.000
H74 Other disorders of middle ear and mastoid
0.727 0.273 0.000
N42 Other disorders of prostate
0.727 0.273 0.000
M91-M94 Chondropathies
0.727 0.273 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.727 0.273 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.726 0.274 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.726 0.274 0.000
N18.2 Chronic kidney disease, stage 2
0.726 0.274 0.000
Q80-Q89 Other congenital malformations
0.725 0.275 0.000
I61 Intracerebral haemorrhage
0.723 0.276 0.000
S00.1 Contusion of eyelid and periocular area
0.723 0.277 0.000
F01 Vascular dementia
0.723 0.277 0.000
U80 Agent resistant to penicillin and related antibiotics
0.722 0.278 0.000
D52 Folate deficiency anaemia
0.721 0.279 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.721 0.279 0.000
N93.9 Abnormal uterine and vaginal bleeding, unspecified
0.720 0.280 0.000
M05-M14 Inflammatory polyarthropathies
0.720 0.280 0.000
F22.0 Delusional disorder
0.720 0.280 0.000
E78.2 Mixed hyperlipidaemia
0.719 0.281 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.718 0.281 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.718 0.282 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.718 0.282 0.000
I74 Arterial embolism and thrombosis
0.718 0.282 0.000
S70-S79 Injuries to the hip and thigh
0.718 0.282 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
F80-F89 Disorders of psychological development
0.717 0.283 0.000
F70-F79 Mental retardation
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
J98.8 Other specified respiratory disorders
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
S81.9 Open wound of lower leg, part unspecified
0.716 0.284 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.715 0.285 0.000
S69 Other and unspecified injuries of wrist and hand
0.715 0.285 0.000
R47.1 Dysarthria and anarthria
0.715 0.285 0.000
D53 Other nutritional anaemias
0.714 0.286 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.714 0.286 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.714 0.286 0.000
G30.9 Alzheimer's disease, unspecified
0.714 0.286 0.000
E40-E46 Malnutrition
0.714 0.286 0.000
D50.1 Sideropenic dysphagia
0.714 0.286 0.000
N98 Complications associated with artificial fertilisation
0.713 0.287 0.000
N91 Absent, scanty and rare menstruation
0.713 0.287 0.000
N96 Habitual aborter
0.713 0.287 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.712 0.288 0.000
F38 Other mood [affective] disorders
0.712 0.288 0.000
F34 Persistent mood [affective] disorders
0.712 0.288 0.000
F30 Manic episode
0.712 0.288 0.000
F39 Unspecified mood [affective] disorder
0.712 0.288 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.712 0.288 0.000
W20-W49 Exposure to inanimate mechanical forces
0.711 0.289 0.000
F48 Other neurotic disorders
0.710 0.290 0.000
F44 Dissociative [conversion] disorders
0.710 0.290 0.000
F42 Obsessive-compulsive disorder
0.710 0.290 0.000
H42 Glaucoma in diseases classified elsewhere
0.710 0.290 0.000
N94.9 Unspecified condition associated with female genital organs and menstrual cycle
0.710 0.290 0.000
N94.5 Secondary dysmenorrhoea
0.710 0.290 0.000
N94.4 Primary dysmenorrhoea
0.710 0.290 0.000
N94.2 Vaginismus
0.710 0.290 0.000
N94.0 Mittelschmerz
0.710 0.290 0.000
S68 Traumatic amputation of wrist and hand
0.709 0.290 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.709 0.291 0.000
N92.6 Irregular menstruation, unspecified
0.707 0.293 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.707 0.293 0.000
G43 Migraine
0.707 0.293 0.000
H40.8 Other glaucoma
0.707 0.293 0.000
H40.6 Glaucoma secondary to drugs
0.707 0.293 0.000
H40.5 Glaucoma secondary to other eye disorders
0.707 0.293 0.000
H40.4 Glaucoma secondary to eye inflammation
0.707 0.293 0.000
H40.3 Glaucoma secondary to eye trauma
0.707 0.293 0.000
B95-B98 Bacterial, viral and other infectious agents
0.707 0.293 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.707 0.293 0.000
J17 Pneumonia in diseases classified elsewhere
0.706 0.294 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.706 0.294 0.000
J12 Viral pneumonia, not elsewhere classified
0.706 0.294 0.000
J11 Influenza, virus not identified
0.706 0.294 0.000
J14 Pneumonia due to Haemophilus influenzae
0.706 0.294 0.000
J09 Influenza due to certain identified influenza virus
0.706 0.294 0.000
J15.1 Pneumonia due to Pseudomonas
0.706 0.294 0.000
R73 Elevated blood glucose level
0.705 0.295 0.000
S08 Traumatic amputation of part of head
0.705 0.295 0.000
S07 Crushing injury of head
0.705 0.295 0.000
S06 Intracranial injury
0.705 0.295 0.000
S04 Injury of cranial nerves
0.705 0.295 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.705 0.295 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.704 0.296 0.000
S01.4 Open wound of cheek and temporomandibular area
0.704 0.296 0.000
R74 Abnormal serum enzyme levels
0.704 0.296 0.000
S67 Crushing injury of wrist and hand
0.703 0.297 0.000
S65 Injury of blood vessels at wrist and hand level
0.703 0.297 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.703 0.297 0.000
R77 Other abnormalities of plasma proteins
0.703 0.297 0.000
R76 Other abnormal immunological findings in serum
0.703 0.297 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.703 0.297 0.000
R71 Abnormality of red blood cells
0.703 0.297 0.000
N72 Inflammatory disease of cervix uteri
0.703 0.297 0.000
M00-M03 Infectious arthropathies
0.703 0.297 0.000
J30-J39 Other diseases of upper respiratory tract
0.702 0.298 0.000
F31.8 Other bipolar affective disorders
0.702 0.298 0.000
F31.7 Bipolar affective disorder, currently in remission
0.702 0.298 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.702 0.298 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.702 0.298 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.702 0.298 0.000
F60 Specific personality disorders
0.702 0.298 0.000
N45 Orchitis and epididymitis
0.701 0.299 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.700 0.300 0.000
J41 Simple and mucopurulent chronic bronchitis
0.700 0.300 0.000
F41.8 Other specified anxiety disorders
0.700 0.300 0.000
F41.3 Other mixed anxiety disorders
0.700 0.300 0.000
R22.7 Localised swelling, mass and lump, multiple sites
0.700 0.300 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.700 0.300 0.000
N87 Dysplasia of cervix uteri
0.700 0.300 0.000
D80-D89 Certain disorders involving the immune mechanism
0.700 0.300 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.699 0.301 0.000
H05 Disorders of orbit
0.699 0.301 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.699 0.301 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.699 0.301 0.000
Y35-Y36 Legal intervention and operations of war
0.699 0.301 0.000
Y10-Y34 Event of undetermined intent
0.699 0.301 0.000
Y00-Y09 Assault
0.699 0.301 0.000
X85-X99 Assault
0.699 0.301 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.699 0.301 0.000
X50-X57 Overexertion, travel and privation
0.699 0.301 0.000
X30-X39 Exposure to forces of nature
0.699 0.301 0.000
X20-X29 Contact with venomous animals and plants
0.699 0.301 0.000
X10-X19 Contact with heat and hot substances
0.699 0.301 0.000
X00-X09 Exposure to smoke, fire and flames
0.699 0.301 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.699 0.301 0.000
W75-W84 Other accidental threats to breathing
0.699 0.301 0.000
W65-W74 Accidental drowning and submersion
0.699 0.301 0.000
W50-W64 Exposure to animate mechanical forces
0.699 0.301 0.000
V98-V99 Other and unspecified transport accidents
0.699 0.301 0.000
V95-V97 Air and space transport accidents
0.699 0.301 0.000
V90-V94 Water transport accidents
0.699 0.301 0.000
V70-V79 Bus occupant injured in transport accident
0.699 0.301 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.699 0.301 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.699 0.301 0.000
V40-V49 Car occupant injured in transport accident
0.699 0.301 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.699 0.301 0.000
V01-V09 Pedestrian injured in transport accident
0.699 0.301 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.699 0.301 0.000
G44 Other headache syndromes
0.698 0.302 0.000
F43.2 Adjustment disorders
0.698 0.302 0.000
N18.8 Other chronic renal failure
0.697 0.303 0.000
N18.1 Chronic kidney disease, stage 1
0.697 0.303 0.000
S61.7 Multiple open wounds of wrist and hand
0.696 0.303 0.000
I12 Hypertensive renal disease
0.697 0.303 0.000
J80 Adult respiratory distress syndrome
0.696 0.304 0.000
F41.1 Generalised anxiety disorder
0.696 0.304 0.000
J18.8 Other pneumonia, organism unspecified
0.695 0.304 0.000
J18.2 Hypostatic pneumonia, unspecified
0.695 0.304 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.695 0.305 0.000
S20-S29 Injuries to the thorax
0.695 0.305 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.695 0.305 0.000
G24 Dystonia
0.695 0.305 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.695 0.305 0.000
E85 Amyloidosis
0.694 0.306 0.000
E84 Cystic fibrosis
0.694 0.306 0.000
E79 Disorders of purine and pyrimidine metabolism
0.694 0.306 0.000
E77 Disorders of glycoprotein metabolism
0.694 0.306 0.000
E76 Disorders of glycosaminoglycan metabolism
0.694 0.306 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.694 0.306 0.000
E74 Other disorders of carbohydrate metabolism
0.694 0.306 0.000
E73 Lactose intolerance
0.694 0.306 0.000
E72 Other disorders of amino-acid metabolism
0.694 0.306 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.694 0.306 0.000
E70 Disorders of aromatic amino-acid metabolism
0.694 0.306 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.694 0.306 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.693 0.306 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.693 0.307 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.693 0.307 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.693 0.307 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.693 0.307 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.693 0.307 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.693 0.307 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.693 0.307 0.000
F11 Mental and behavioural disorders due to use of opioids
0.693 0.307 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.692 0.308 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.692 0.308 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.692 0.308 0.000
S01.0 Open wound of scalp
0.692 0.308 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.691 0.309 0.000
O00-O08 Pregnancy with abortive outcome
0.691 0.309 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.690 0.310 0.000
G70-G73 Diseases of myoneural junction and muscle
0.688 0.312 0.000
N97.1 Female infertility of tubal origin
0.687 0.313 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.686 0.314 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.686 0.314 0.000
F02 Dementia in other diseases classified elsewhere
0.686 0.314 0.000
F09 Unspecified organic or symptomatic mental disorder
0.686 0.314 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.686 0.314 0.000
F45 Somatoform disorders
0.686 0.314 0.000
M60-M63 Disorders of muscles
0.685 0.315 0.000
F99 Mental disorder, not otherwise specified
0.684 0.315 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.684 0.316 0.000
F10.9 Unspecified mental and behavioural disorder
0.684 0.316 0.000
F10.8 Other mental and behavioural disorders
0.684 0.316 0.000
F10.7 Residual and late-onset psychotic disorder
0.684 0.316 0.000
F10.6 Amnesic syndrome
0.684 0.316 0.000
F10.5 Psychotic disorder
0.684 0.316 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.683 0.316 0.000
S01.8 Open wound of other parts of head
0.683 0.317 0.000
V20-V29 Motorcycle rider injured in transport accident
0.683 0.317 0.000
M89 Other disorders of bone
0.683 0.317 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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