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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs113040697
log Bayes Factor = 28.1855
Chromosome 8   position 118,185,308  (GRCh37) Explore rs113040697 on Ensembl!
Variant rs113040697 is part of Cluster X0049

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
0.999 0.001 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.999 0.001 0.000
I25 Chronic ischaemic heart disease
0.998 0.002 0.000
Chapter XX External causes of morbidity and mortality
0.998 0.002 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.997 0.003 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.996 0.004 0.000
I20 Angina pectoris
0.996 0.004 0.000
Chapter XIV Diseases of the genitourinary system
0.994 0.006 0.000
I60-I69 Cerebrovascular diseases
0.991 0.009 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.991 0.009 0.000
I51 Complications and ill-defined descriptions of heart disease
0.990 0.010 0.000
E10-E14 Diabetes mellitus
0.989 0.011 0.000
I20.0 Unstable angina
0.986 0.014 0.000
I50 Heart failure
0.985 0.015 0.000
I51.7 Cardiomegaly
0.985 0.015 0.000
R20 Disturbances of skin sensation
0.979 0.021 0.000
R00 Abnormalities of heart beat
0.976 0.024 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.976 0.024 0.000
Z51 Other medical care
0.976 0.024 0.000
H30-H36 Disorders of choroid and retina
0.971 0.029 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.965 0.035 0.000
Z53.0 Procedure not carried out because of contraindication
0.963 0.037 0.000
Chapter I Certain infectious and parasitic diseases
0.963 0.037 0.000
R00.2 Palpitations
0.959 0.041 0.000
I50.0 Congestive heart failure
0.958 0.042 0.000
R05 Cough
0.958 0.042 0.000
Z53.8 Procedure not carried out for other reasons
0.957 0.043 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.957 0.043 0.000
R07 Pain in throat and chest
0.953 0.047 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.948 0.052 0.000
W00-W19 Falls
0.944 0.055 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.944 0.056 0.000
R20.2 Paraesthesia of skin
0.943 0.057 0.000
I25.1 Atherosclerotic heart disease
0.943 0.057 0.000
E10 Insulin-dependent diabetes mellitus
0.941 0.059 0.000
E11 Non-insulin-dependent diabetes mellitus
0.938 0.062 0.000
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons
0.937 0.063 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.932 0.068 0.000
I34 Nonrheumatic mitral valve disorders
0.932 0.068 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.929 0.071 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.928 0.072 0.000
Z51.0 Radiotherapy session
0.926 0.074 0.000
Chapter VI Diseases of the nervous system
0.925 0.075 0.000
Z51.2 Other chemotherapy
0.924 0.076 0.000
H02 Other disorders of eyelid
0.923 0.077 0.000
N30-N39 Other diseases of urinary system
0.923 0.077 0.000
O60-O75 Complications of labour and delivery
0.920 0.080 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.920 0.080 0.000
I25.2 Old myocardial infarction
0.917 0.083 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.916 0.084 0.000
R02 Gangrene, not elsewhere classified
0.914 0.086 0.000
N10-N16 Renal tubulo-interstitial diseases
0.912 0.088 0.000
N17-N19 Renal failure
0.908 0.092 0.000
M50-M54 Other dorsopathies
0.908 0.092 0.000
N32 Other disorders of bladder
0.908 0.092 0.000
R03.1 Nonspecific low blood-pressure reading
0.905 0.095 0.000
R47-R49 Symptoms and signs involving speech and voice
0.902 0.098 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.901 0.099 0.000
E70-E90 Metabolic disorders
0.900 0.100 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.899 0.101 0.000
W19 Unspecified fall
0.898 0.102 0.000
I63 Cerebral infarction
0.898 0.102 0.000
Y45.0 Opioids and related analgesics
0.898 0.102 0.000
D50-D53 Nutritional anaemias
0.896 0.104 0.000
I20.9 Angina pectoris, unspecified
0.891 0.109 0.000
I34.0 Mitral (valve) insufficiency
0.891 0.109 0.000
Chapter XXII Codes for special purposes
0.890 0.110 0.000
H33 Retinal detachments and breaks
0.888 0.112 0.000
I38 Endocarditis, valve unspecified
0.886 0.114 0.000
O70 Perineal laceration during delivery
0.885 0.115 0.000
Z53.9 Procedure not carried out, unspecified reason
0.884 0.116 0.000
I50.9 Heart failure, unspecified
0.881 0.119 0.000
I61 Intracerebral haemorrhage
0.880 0.120 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.879 0.121 0.000
N18 Chronic renal failure
0.877 0.123 0.000
H04 Disorders of lachrymal system
0.875 0.125 0.000
H43-H45 Disorders of vitreous body and globe
0.873 0.127 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.872 0.128 0.000
I31 Other diseases of pericardium
0.870 0.130 0.000
Y45.2 Propionic acid derivatives
0.869 0.131 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.861 0.139 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.860 0.140 0.000
E10.9 Without complications
0.858 0.142 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.855 0.145 0.000
N99-N99 Other disorders of the genitourinary system
0.854 0.146 0.000
Chapter II Neoplasms
0.849 0.151 0.000
R47 Speech disturbances, not elsewhere classified
0.849 0.151 0.000
H33.2 Serous retinal detachment
0.848 0.152 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.848 0.152 0.000
Z92 Personal history of medical treatment
0.847 0.153 0.000
E00-E07 Disorders of thyroid gland
0.843 0.157 0.000
N32.8 Other specified disorders of bladder
0.842 0.158 0.000
Chapter VIII Diseases of the ear and mastoid process
0.842 0.158 0.000
Chapter XI Diseases of the digestive system
0.842 0.158 0.000
B95-B98 Bacterial, viral and other infectious agents
0.841 0.159 0.000
R21 Rash and other nonspecific skin eruption
0.841 0.159 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.839 0.161 0.000
I60 Subarachnoid haemorrhage
0.838 0.162 0.000
M51 Other intervertebral disk disorders
0.835 0.165 0.000
Z43 Attention to artificial openings
0.834 0.166 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.834 0.166 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.832 0.168 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.832 0.168 0.000
I45 Other conduction disorders
0.831 0.169 0.000
I67 Other cerebrovascular diseases
0.829 0.171 0.000
I37 Pulmonary valve disorders
0.827 0.173 0.000
Z60 Problems related to social environment
0.827 0.173 0.000
Z49 Care involving dialysis
0.826 0.174 0.000
H25-H28 Disorders of lens
0.825 0.175 0.000
W19.9 Unspecified place
0.824 0.176 0.000
N00-N08 Glomerular diseases
0.824 0.176 0.000
R07.3 Other chest pain
0.823 0.177 0.000
E10.4 With neurological complications
0.823 0.177 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.820 0.180 0.000
A30-A49 Other bacterial diseases
0.819 0.181 0.000
E14 Unspecified diabetes mellitus
0.818 0.182 0.000
K70-K77 Diseases of liver
0.816 0.184 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.815 0.185 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.814 0.186 0.000
Z97 Presence of other devices
0.813 0.187 0.000
H35 Other retinal disorders
0.813 0.187 0.000
G40-G47 Episodic and paroxysmal disorders
0.812 0.188 0.000
R07.2 Precordial pain
0.811 0.189 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.810 0.190 0.000
E11.9 Without complications
0.810 0.190 0.000
N32.0 Bladder-neck obstruction
0.809 0.191 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.805 0.195 0.000
N32.3 Diverticulum of bladder
0.805 0.195 0.000
Z63 Other problems related to primary support group, including family circumstances
0.803 0.197 0.000
I69 Sequelae of cerebrovascular disease
0.803 0.197 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.802 0.198 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.802 0.198 0.000
M54 Dorsalgia
0.802 0.198 0.000
O63 Long labour
0.802 0.198 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.801 0.199 0.000
B25-B34 Other viral diseases
0.799 0.201 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.799 0.201 0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension
0.798 0.202 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.796 0.204 0.000
H34 Retinal vascular occlusions
0.796 0.204 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.796 0.204 0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen
0.796 0.204 0.000
A00-A09 Intestinal infectious diseases
0.794 0.206 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.793 0.207 0.000
H36 Retinal disorders in diseases classified elsewhere
0.792 0.208 0.000
O70.0 First degree perineal laceration during delivery
0.792 0.208 0.000
I63.9 Cerebral infarction, unspecified
0.791 0.209 0.000
C15-C26 Malignant neoplasms of digestive organs
0.789 0.211 0.000
N81 Female genital prolapse
0.788 0.212 0.000
H10-H13 Disorders of conjunctiva
0.787 0.213 0.000
G20-G26 Extrapyramidal and movement disorders
0.786 0.214 0.000
Y52 Agents primarily affecting the cardiovascular system
0.785 0.215 0.000
N18.5 Chronic kidney disease, stage 5
0.785 0.215 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.784 0.216 0.000
Y43 Primarily systemic agents
0.783 0.217 0.000
C64-C68 Malignant neoplasms of urinary tract
0.783 0.217 0.000
E11.3 With ophthalmic complications
0.783 0.217 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.782 0.217 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.782 0.218 0.000
S80-S89 Injuries to the knee and lower leg
0.780 0.220 0.000
I24 Other acute ischaemic heart diseases
0.780 0.220 0.000
H02.6 Xanthelasma of eyelid
0.777 0.222 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.777 0.223 0.000
I33 Acute and subacute endocarditis
0.776 0.224 0.000
R23 Other skin changes
0.775 0.225 0.000
E11.2 With renal complications
0.775 0.225 0.000
W19.4 Street and highway
0.775 0.225 0.000
Z51.3 Blood transfusion without reported diagnosis
0.774 0.226 0.000
R47.8 Other and unspecified speech disturbances
0.774 0.226 0.000
Z86 Personal history of certain other diseases
0.774 0.226 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.773 0.227 0.000
H02.0 Entropion and trichiasis of eyelid
0.773 0.227 0.000
Z54 Convalescence
0.771 0.229 0.000
I20.8 Other forms of angina pectoris
0.771 0.229 0.000
D50 Iron deficiency anaemia
0.769 0.231 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.768 0.232 0.000
E11.4 With neurological complications
0.768 0.232 0.000
H25 Senile cataract
0.767 0.233 0.000
D51 Vitamin B12 deficiency anaemia
0.767 0.233 0.000
Z51.9 Medical care, unspecified
0.767 0.233 0.000
H43 Disorders of vitreous body
0.765 0.235 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.763 0.237 0.000
I51.9 Heart disease, unspecified
0.761 0.239 0.000
Z91.5 Personal history of self-harm
0.760 0.240 0.000
E86 Volume depletion
0.759 0.241 0.000
R01 Cardiac murmurs and other cardiac sounds
0.758 0.242 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.756 0.244 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.756 0.244 0.000
N60-N64 Disorders of breast
0.756 0.244 0.000
H55-H59 Other disorders of eye and adnexa
0.755 0.245 0.000
I30 Acute pericarditis
0.754 0.246 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.754 0.246 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.753 0.247 0.000
Z60.2 Living alone
0.753 0.247 0.000
H02.9 Disorder of eyelid, unspecified
0.753 0.247 0.000
M50 Cervical disk disorders
0.750 0.250 0.000
R22.0 Localised swelling, mass and lump, head
0.750 0.250 0.000
L20-L30 Dermatitis and eczema
0.750 0.250 0.000
D52 Folate deficiency anaemia
0.750 0.250 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.748 0.252 0.000
R22.2 Localised swelling, mass and lump, trunk
0.746 0.254 0.000
R07.4 Chest pain, unspecified
0.746 0.254 0.000
Z95.1 Presence of aortocoronary bypass graft
0.744 0.256 0.000
V80-V89 Other land transport accidents
0.743 0.257 0.000
E04 Other non-toxic goitre
0.743 0.257 0.000
R07.0 Pain in throat
0.742 0.258 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.741 0.259 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.741 0.259 0.000
Z51.5 Palliative care
0.740 0.260 0.000
N18.9 Chronic renal failure, unspecified
0.740 0.260 0.000
R45 Symptoms and signs involving emotional state
0.740 0.260 0.000
Z52 Donors of organs and tissues
0.739 0.261 0.000
H25.0 Senile incipient cataract
0.739 0.261 0.000
M51.2 Other specified intervertebral disk displacement
0.739 0.261 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.739 0.261 0.000
I05-I09 Chronic rheumatic heart diseases
0.739 0.261 0.000
N95 Menopausal and other perimenopausal disorders
0.738 0.262 0.000
E20-E35 Disorders of other endocrine glands
0.738 0.262 0.000
O70.9 Perineal laceration during delivery, unspecified
0.737 0.263 0.000
N35 Urethral stricture
0.737 0.263 0.000
Z92.3 Personal history of irradiation
0.736 0.264 0.000
R07.1 Chest pain on breathing
0.734 0.266 0.000
H01 Other inflammation of eyelid
0.734 0.266 0.000
O70.2 Third degree perineal laceration during delivery
0.733 0.267 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.733 0.267 0.000
R22.9 Localised swelling, mass and lump, unspecified
0.732 0.268 0.000
N18.4 Chronic kidney disease, stage 4
0.732 0.268 0.000
Z41 Procedures for purposes other than remedying health state
0.731 0.269 0.000
R22.4 Localised swelling, mass and lump, lower limb
0.731 0.269 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.729 0.271 0.000
M20-M25 Other joint disorders
0.728 0.272 0.000
M86-M90 Other osteopathies
0.727 0.273 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.726 0.274 0.000
H02.8 Other specified disorders of eyelid
0.726 0.274 0.000
I31.3 Pericardial effusion (noninflammatory)
0.726 0.274 0.000
I22 Subsequent myocardial infarction
0.726 0.274 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.725 0.275 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.725 0.275 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.725 0.275 0.000
Z40 Prophylactic surgery
0.723 0.277 0.000
K75 Other inflammatory liver diseases
0.723 0.277 0.000
Y44 Agents primarily affecting blood constituents
0.722 0.278 0.000
Z97.4 Presence of external hearing-aid
0.722 0.278 0.000
O66 Other obstructed labour
0.722 0.278 0.000
Y54.5 Other diuretics
0.721 0.279 0.000
W20-W49 Exposure to inanimate mechanical forces
0.720 0.280 0.000
N36 Other disorders of urethra
0.720 0.280 0.000
S20-S29 Injuries to the thorax
0.719 0.281 0.000
R47.0 Dysphasia and aphasia
0.719 0.281 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.719 0.281 0.000
N86 Erosion and ectropion of cervix uteri
0.719 0.281 0.000
Z84 Family history of other conditions
0.718 0.282 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
Z44 Fitting and adjustment of external prosthetic device
0.717 0.283 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.716 0.283 0.000
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure
0.716 0.284 0.000
A41 Other septicaemia
0.716 0.284 0.000
I25.6 Silent myocardial ischaemia
0.716 0.284 0.000
I25.4 Coronary artery aneurysm
0.716 0.284 0.000
I25.3 Aneurysm of heart
0.716 0.284 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.716 0.284 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.716 0.284 0.000
Y35-Y36 Legal intervention and operations of war
0.716 0.284 0.000
Y10-Y34 Event of undetermined intent
0.716 0.284 0.000
Y00-Y09 Assault
0.716 0.284 0.000
X85-X99 Assault
0.716 0.284 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.716 0.284 0.000
X50-X57 Overexertion, travel and privation
0.716 0.284 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.716 0.284 0.000
X30-X39 Exposure to forces of nature
0.716 0.284 0.000
X20-X29 Contact with venomous animals and plants
0.716 0.284 0.000
X10-X19 Contact with heat and hot substances
0.716 0.284 0.000
X00-X09 Exposure to smoke, fire and flames
0.716 0.284 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.716 0.284 0.000
W75-W84 Other accidental threats to breathing
0.716 0.284 0.000
W65-W74 Accidental drowning and submersion
0.716 0.284 0.000
W50-W64 Exposure to animate mechanical forces
0.716 0.284 0.000
V98-V99 Other and unspecified transport accidents
0.716 0.284 0.000
V95-V97 Air and space transport accidents
0.716 0.284 0.000
V90-V94 Water transport accidents
0.716 0.284 0.000
V70-V79 Bus occupant injured in transport accident
0.716 0.284 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.716 0.284 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.716 0.284 0.000
V40-V49 Car occupant injured in transport accident
0.716 0.284 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.716 0.284 0.000
V01-V09 Pedestrian injured in transport accident
0.716 0.284 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.716 0.284 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.716 0.284 0.000
I42 Cardiomyopathy
0.715 0.285 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.715 0.285 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.714 0.286 0.000
E40-E46 Malnutrition
0.714 0.286 0.000
I20.1 Angina pectoris with documented spasm
0.714 0.286 0.000
D50.9 Iron deficiency anaemia, unspecified
0.713 0.287 0.000
Y45.1 Salicylates
0.713 0.287 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.713 0.287 0.000
I31.9 Disease of pericardium, unspecified
0.711 0.289 0.000
N81.6 Rectocele
0.711 0.289 0.000
M80-M85 Disorders of bone density and structure
0.711 0.289 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.711 0.289 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.711 0.289 0.000
I62 Other nontraumatic intracranial haemorrhage
0.711 0.289 0.000
Y59 Other and unspecified vaccines and biological substances
0.711 0.289 0.000
Y58 Bacterial vaccines
0.711 0.289 0.000
Y57 Other and unspecified drugs and medicaments
0.711 0.289 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.711 0.289 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.711 0.289 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.711 0.289 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.711 0.289 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.711 0.289 0.000
Y48 Anaesthetics and therapeutic gases
0.711 0.289 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.711 0.289 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.711 0.289 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.711 0.289 0.000
I51.6 Cardiovascular disease, unspecified
0.710 0.290 0.000
I51.5 Myocardial degeneration
0.710 0.290 0.000
I51.4 Myocarditis, unspecified
0.710 0.290 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.710 0.290 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.710 0.290 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.710 0.290 0.000
I51.0 Cardiac septal defect, acquired
0.710 0.290 0.000
Y86 Sequelae of other accidents
0.710 0.290 0.000
I44 Atrioventricular and left bundle-branch block
0.710 0.290 0.000
M54.1 Radiculopathy
0.710 0.290 0.000
H00 Hordeolum and chalazion
0.710 0.290 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.710 0.290 0.000
E13 Other specified diabetes mellitus
0.709 0.291 0.000
E12 Malnutrition-related diabetes mellitus
0.709 0.291 0.000
Z48 Other surgical follow-up care
0.709 0.291 0.000
O63.1 Prolonged second stage (of labour)
0.709 0.291 0.000
S70-S79 Injuries to the hip and thigh
0.708 0.292 0.000
U88 Agent resistant to multiple antibiotics
0.707 0.292 0.000
V20-V29 Motorcycle rider injured in transport accident
0.707 0.293 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.705 0.295 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.704 0.296 0.000
H35.8 Other specified retinal disorders
0.704 0.296 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.703 0.297 0.000
I37.1 Pulmonary valve insufficiency
0.703 0.297 0.000
C50-C50 Malignant neoplasm of breast
0.702 0.298 0.000
R20.3 Hyperaesthesia
0.702 0.298 0.000
R20.1 Hypoaesthesia of skin
0.702 0.298 0.000
R20.0 Anaesthesia of skin
0.702 0.298 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.702 0.298 0.000
K70 Alcoholic liver disease
0.702 0.298 0.000
Z43.1 Attention to gastrostomy
0.701 0.299 0.000
Z91.6 Personal history of other physical trauma
0.701 0.299 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.700 0.300 0.000
H05 Disorders of orbit
0.700 0.300 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.700 0.300 0.000
H80-H83 Diseases of inner ear
0.700 0.300 0.000
Z51.6 Desensitisation to allergens
0.700 0.300 0.000
R40 Somnolence, stupor and coma
0.699 0.301 0.000
H02.5 Other disorders affecting eyelid function
0.698 0.301 0.000
N11 Chronic tubulo-interstitial nephritis
0.698 0.302 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.698 0.302 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.698 0.302 0.000
R22.3 Localised swelling, mass and lump, upper limb
0.698 0.302 0.000
H53-H54 Visual disturbances and blindness
0.698 0.302 0.000
C18 Malignant neoplasm of colon
0.697 0.303 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.696 0.304 0.000
H31 Other disorders of choroid
0.696 0.304 0.000
H30 Chorioretinal inflammation
0.696 0.304 0.000
V10-V19 Pedal cyclist injured in transport accident
0.695 0.305 0.000
H65-H75 Diseases of middle ear and mastoid
0.694 0.306 0.000
Y40 Systemic antibiotics
0.693 0.306 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.693 0.307 0.000
H02.4 Ptosis of eyelid
0.693 0.307 0.000
O70.1 Second degree perineal laceration during delivery
0.692 0.308 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.692 0.308 0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.692 0.308 0.000
Y45.8 Other analgesics and antipyretics
0.692 0.308 0.000
Y45.5 4-Aminophenol derivatives
0.692 0.308 0.000
Y45.4 Antirheumatics
0.692 0.308 0.000
R50-R69 General symptoms and signs
0.692 0.308 0.000
E10.3 With ophthalmic complications
0.690 0.310 0.000
B99-B99 Other infectious diseases
0.690 0.310 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.690 0.310 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.690 0.310 0.000
B65-B83 Helminthiases
0.690 0.310 0.000
B50-B64 Protozoal diseases
0.690 0.310 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.690 0.310 0.000
B15-B19 Viral hepatitis
0.690 0.310 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.690 0.310 0.000
A80-A89 Viral infections of the central nervous system
0.690 0.310 0.000
A75-A79 Rickettsioses
0.690 0.310 0.000
A70-A74 Other diseases caused by chlamydiae
0.690 0.310 0.000
A65-A69 Other spirochaetal diseases
0.690 0.310 0.000
A20-A28 Certain zoonotic bacterial diseases
0.690 0.310 0.000
A15-A19 Tuberculosis
0.690 0.310 0.000
E50-E64 Other nutritional deficiencies
0.689 0.311 0.000
N99.3 Prolapse of vaginal vault after hysterectomy
0.688 0.312 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.688 0.312 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.688 0.312 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.687 0.313 0.000
I47 Paroxysmal tachycardia
0.686 0.314 0.000
E14.9 Without complications
0.686 0.314 0.000
I50.1 Left ventricular failure
0.686 0.314 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.685 0.315 0.000
Y89 Sequelae of other external causes
0.685 0.315 0.000
I25.5 Ischaemic cardiomyopathy
0.684 0.316 0.000
N32.1 Vesicointestinal fistula
0.683 0.317 0.000
Z89 Acquired absence of limb
0.683 0.317 0.000
K90-K93 Other diseases of the digestive system
0.683 0.317 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.682 0.317 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.682 0.317 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.682 0.318 0.000
Z86.4 Personal history of psychoactive substance abuse
0.682 0.318 0.000
B34 Viral infection of unspecified site
0.681 0.318 0.000
A08 Viral and other specified intestinal infections
0.681 0.319 0.000
E88 Other metabolic disorders
0.680 0.319 0.000
Z45 Adjustment and management of implanted device
0.680 0.320 0.000
G47 Sleep disorders
0.680 0.320 0.000
D55-D59 Haemolytic anaemias
0.680 0.320 0.000
N25-N29 Other disorders of kidney and ureter
0.679 0.321 0.000
W18 Other fall on same level
0.677 0.323 0.000
W17 Other fall from one level to another
0.677 0.323 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.677 0.323 0.000
W15 Fall from cliff
0.677 0.323 0.000
W14 Fall from tree
0.677 0.323 0.000
W13 Fall from, out of or through building or structure
0.677 0.323 0.000
W12 Fall on and from scaffolding
0.677 0.323 0.000
W11 Fall on and from ladder
0.677 0.323 0.000
W10 Fall on and from stairs and steps
0.677 0.323 0.000
W09 Fall involving playground equipment
0.677 0.323 0.000
W08 Fall involving other furniture
0.677 0.323 0.000
W07 Fall involving chair
0.677 0.323 0.000
W06 Fall involving bed
0.677 0.323 0.000
W05 Fall involving wheelchair
0.677 0.323 0.000
W04 Fall while being carried or supported by other persons
0.677 0.323 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.677 0.323 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.677 0.323 0.000
W00 Fall on same level involving ice and snow
0.677 0.323 0.000
M91-M94 Chondropathies
0.677 0.323 0.000
Z63.8 Other specified problems related to primary support group
0.676 0.323 0.000
X60-X84 Intentional self-harm
0.676 0.324 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.676 0.324 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.675 0.325 0.000
E10.8 With unspecified complications
0.674 0.325 0.000
E10.7 With multiple complications
0.674 0.325 0.000
E10.6 With other specified complications
0.674 0.325 0.000
E10.5 With peripheral circulatory complications
0.674 0.325 0.000
E10.2 With renal complications
0.674 0.325 0.000
E10.1 With ketoacidosis
0.674 0.325 0.000
E10.0 With coma
0.674 0.325 0.000
M65-M68 Disorders of synovium and tendon
0.674 0.326 0.000
D69 Purpura and other haemorrhagic conditions
0.674 0.326 0.000
K73 Chronic hepatitis, not elsewhere classified
0.674 0.326 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.673 0.327 0.000
E11.8 With unspecified complications
0.673 0.327 0.000
E11.7 With multiple complications
0.673 0.327 0.000
E11.6 With other specified complications
0.673 0.327 0.000
E11.1 With ketoacidosis
0.673 0.327 0.000
E11.0 With coma
0.673 0.327 0.000
L60-L75 Disorders of skin appendages
0.672 0.328 0.000
Z97.8 Presence of other specified devices
0.672 0.328 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.671 0.329 0.000
K76 Other diseases of liver
0.671 0.329 0.000
I27 Other pulmonary heart diseases
0.669 0.331 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.669 0.331 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.669 0.331 0.000
M60-M63 Disorders of muscles
0.668 0.331 0.000
M00-M03 Infectious arthropathies
0.668 0.331 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.668 0.331 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.668 0.331 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.668 0.331 0.000
Chapter V Mental and behavioural disorders
0.667 0.333 0.000
R04 Haemorrhage from respiratory passages
0.667 0.333 0.000
G40 Epilepsy
0.667 0.333 0.000
Z65 Problems related to other psychosocial circumstances
0.666 0.334 0.000
Z64 Problems related to certain psychosocial circumstances
0.666 0.334 0.000
Z62 Other problems related to upbringing
0.666 0.334 0.000
Z61 Problems related to negative life events in childhood
0.666 0.334 0.000
Z59 Problems related to housing and economic circumstances
0.666 0.334 0.000
Z58 Problems related to physical environment
0.666 0.334 0.000
Z56 Problems related to employment and unemployment
0.666 0.334 0.000
Z55 Problems related to education and literacy
0.666 0.334 0.000
Z49.1 Extracorporeal dialysis
0.666 0.334 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.666 0.334 0.000
S10-S19 Injuries to the neck
0.666 0.334 0.000
T79-T79 Certain early complications of trauma
0.665 0.335 0.000
O85-O92 Complications predominantly related to the puerperium
0.665 0.335 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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