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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs113070825
log Bayes Factor = 18.5714
Chromosome 7   position 17,430,916  (GRCh37) Explore rs113070825 on Ensembl!
Variant rs113070825 is part of Cluster X0246

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
R50-R69 General symptoms and signs
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
0.999 0.001 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.998 0.002 0.000
N30-N39 Other diseases of urinary system
0.997 0.003 0.000
I95 Hypotension
0.997 0.003 0.000
I95.9 Hypotension, unspecified
0.995 0.005 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.994 0.006 0.000
R50 Fever of unknown origin
0.991 0.009 0.000
S00-S09 Injuries to the head
0.990 0.010 0.000
I25 Chronic ischaemic heart disease
0.989 0.011 0.000
S40-S49 Injuries to the shoulder and upper arm
0.987 0.013 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.984 0.016 0.000
S00 Superficial injury of head
0.981 0.019 0.000
R50.9 Fever, unspecified
0.979 0.021 0.000
N40-N51 Diseases of male genital organs
0.978 0.022 0.000
I50 Heart failure
0.976 0.024 0.000
I49 Other cardiac arrhythmias
0.974 0.026 0.000
N39 Other disorders of urinary system
0.968 0.032 0.000
N10-N16 Renal tubulo-interstitial diseases
0.967 0.033 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.962 0.038 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.956 0.044 0.000
S00.9 Superficial injury of head, part unspecified
0.953 0.047 0.000
I21 Acute myocardial infarction
0.952 0.048 0.000
N40 Hyperplasia of prostate
0.949 0.051 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.947 0.053 0.000
S42 Fracture of shoulder and upper arm
0.947 0.053 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.945 0.055 0.000
I77 Other disorders of arteries and arterioles
0.943 0.057 0.000
Chapter I Certain infectious and parasitic diseases
0.942 0.058 0.000
R30-R39 Symptoms and signs involving the urinary system
0.941 0.059 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.939 0.061 0.000
N32 Other disorders of bladder
0.937 0.063 0.000
I45 Other conduction disorders
0.930 0.070 0.000
R55 Syncope and collapse
0.925 0.075 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.924 0.076 0.000
I73 Other peripheral vascular diseases
0.917 0.083 0.000
I47 Paroxysmal tachycardia
0.917 0.083 0.000
M20-M25 Other joint disorders
0.912 0.088 0.000
N45 Orchitis and epididymitis
0.905 0.095 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.904 0.096 0.000
N39.3 Stress incontinence
0.902 0.098 0.000
I95.1 Orthostatic hypotension
0.902 0.098 0.000
I50.9 Heart failure, unspecified
0.902 0.098 0.000
R35 Polyuria
0.897 0.103 0.000
I44 Atrioventricular and left bundle-branch block
0.896 0.104 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.896 0.104 0.000
S42.2 Fracture of upper end of humerus
0.896 0.104 0.000
S00.8 Superficial injury of other parts of head
0.893 0.107 0.000
R63 Symptoms and signs concerning food and fluid intake
0.893 0.107 0.000
I77.1 Stricture of artery
0.893 0.107 0.000
I49.5 Sick sinus syndrome
0.890 0.110 0.000
I47.2 Ventricular tachycardia
0.889 0.111 0.000
I50.0 Congestive heart failure
0.888 0.112 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.885 0.115 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.883 0.117 0.000
I31 Other diseases of pericardium
0.883 0.117 0.000
N39.9 Disorder of urinary system, unspecified
0.877 0.123 0.000
N39.8 Other specified disorders of urinary system
0.877 0.123 0.000
I49.0 Ventricular fibrillation and flutter
0.875 0.125 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.869 0.131 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.869 0.131 0.000
T66-T78 Other and unspecified effects of external causes
0.865 0.135 0.000
I25.1 Atherosclerotic heart disease
0.864 0.136 0.000
I45.1 Other and unspecified right bundle-branch block
0.861 0.139 0.000
R41.0 Disorientation, unspecified
0.861 0.139 0.000
M65-M68 Disorders of synovium and tendon
0.860 0.140 0.000
S42.20 Fracture of upper end of humerus (closed)
0.859 0.141 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.858 0.142 0.000
I20 Angina pectoris
0.857 0.143 0.000
S80-S89 Injuries to the knee and lower leg
0.856 0.144 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.854 0.146 0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.853 0.147 0.000
S10-S19 Injuries to the neck
0.852 0.148 0.000
R07.3 Other chest pain
0.852 0.148 0.000
E70-E90 Metabolic disorders
0.852 0.148 0.000
S01 Open wound of head
0.851 0.149 0.000
I72 Other aneurysm
0.851 0.149 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.851 0.149 0.000
R07 Pain in throat and chest
0.851 0.149 0.000
R30 Pain associated with micturition
0.849 0.151 0.000
Chapter XX External causes of morbidity and mortality
0.843 0.157 0.000
D80-D89 Certain disorders involving the immune mechanism
0.842 0.158 0.000
E10-E14 Diabetes mellitus
0.842 0.158 0.000
R53 Malaise and fatigue
0.839 0.161 0.000
I05-I09 Chronic rheumatic heart diseases
0.839 0.161 0.000
R51 Headache
0.837 0.163 0.000
N32.8 Other specified disorders of bladder
0.837 0.163 0.000
I73.9 Peripheral vascular disease, unspecified
0.834 0.166 0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified
0.833 0.167 0.000
S43.0 Dislocation of shoulder joint
0.831 0.169 0.000
N30 Cystitis
0.827 0.173 0.000
N60-N64 Disorders of breast
0.825 0.175 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.825 0.175 0.000
M70-M79 Other soft tissue disorders
0.824 0.176 0.000
N32.9 Bladder disorder, unspecified
0.822 0.178 0.000
M21 Other acquired deformities of limbs
0.821 0.179 0.000
I42 Cardiomyopathy
0.818 0.182 0.000
A30-A49 Other bacterial diseases
0.811 0.189 0.000
I78 Diseases of capillaries
0.809 0.191 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.809 0.191 0.000
S42.1 Fracture of scapula
0.808 0.192 0.000
I71 Aortic aneurysm and dissection
0.802 0.198 0.000
M25 Other joint disorders, not elsewhere classified
0.802 0.198 0.000
N99-N99 Other disorders of the genitourinary system
0.800 0.200 0.000
R50.8 Other specified fever
0.798 0.202 0.000
B35-B49 Mycoses
0.798 0.202 0.000
R59 Enlarged lymph nodes
0.798 0.202 0.000
E20-E35 Disorders of other endocrine glands
0.796 0.204 0.000
I22 Subsequent myocardial infarction
0.795 0.205 0.000
I20.9 Angina pectoris, unspecified
0.793 0.207 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.791 0.209 0.000
D86 Sarcoidosis
0.790 0.210 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.789 0.211 0.000
Chapter V Mental and behavioural disorders
0.785 0.215 0.000
E65-E68 Obesity and other hyperalimentation
0.784 0.216 0.000
R30.0 Dysuria
0.783 0.217 0.000
N42 Other disorders of prostate
0.782 0.218 0.000
Q21 Congenital malformations of cardiac septa
0.781 0.219 0.000
M23 Internal derangement of knee
0.781 0.219 0.000
S00.1 Contusion of eyelid and periocular area
0.781 0.219 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.780 0.220 0.000
M60-M63 Disorders of muscles
0.780 0.220 0.000
I50.1 Left ventricular failure
0.779 0.221 0.000
S40 Superficial injury of shoulder and upper arm
0.779 0.221 0.000
I25.2 Old myocardial infarction
0.779 0.221 0.000
R63.0 Anorexia
0.778 0.222 0.000
R50.0 Fever with chills
0.777 0.223 0.000
I77.6 Arteritis, unspecified
0.777 0.223 0.000
N63 Unspecified lump in breast
0.775 0.225 0.000
I25.5 Ischaemic cardiomyopathy
0.775 0.225 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.774 0.226 0.000
M34 Systemic sclerosis
0.774 0.226 0.000
M65 Synovitis and tenosynovitis
0.773 0.227 0.000
M86-M90 Other osteopathies
0.772 0.227 0.000
I49.3 Ventricular premature depolarisation
0.772 0.228 0.000
E10 Insulin-dependent diabetes mellitus
0.772 0.228 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.771 0.229 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.771 0.229 0.000
N32.1 Vesicointestinal fistula
0.770 0.230 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.770 0.230 0.000
I33 Acute and subacute endocarditis
0.768 0.232 0.000
M25.7 Osteophyte
0.767 0.233 0.000
R61 Hyperhidrosis
0.767 0.233 0.000
I44.0 Atrioventricular block, first degree
0.764 0.236 0.000
S82 Fracture of lower leg, including ankle
0.763 0.237 0.000
Chapter VIII Diseases of the ear and mastoid process
0.757 0.243 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.756 0.243 0.000
I37 Pulmonary valve disorders
0.756 0.244 0.000
I49.8 Other specified cardiac arrhythmias
0.755 0.245 0.000
Z95.1 Presence of aortocoronary bypass graft
0.755 0.245 0.000
S09 Other and unspecified injuries of head
0.754 0.246 0.000
I36 Nonrheumatic tricuspid valve disorders
0.754 0.246 0.000
R01 Cardiac murmurs and other cardiac sounds
0.753 0.247 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.753 0.247 0.000
R52 Pain, not elsewhere classified
0.752 0.248 0.000
I31.9 Disease of pericardium, unspecified
0.751 0.248 0.000
D50-D53 Nutritional anaemias
0.750 0.250 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.750 0.250 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.749 0.251 0.000
M91-M94 Chondropathies
0.747 0.253 0.000
I73.0 Raynaud's syndrome
0.747 0.253 0.000
R40 Somnolence, stupor and coma
0.746 0.254 0.000
E83 Disorders of mineral metabolism
0.746 0.254 0.000
R57 Shock, not elsewhere classified
0.745 0.254 0.000
D60-D64 Aplastic and other anaemias
0.745 0.255 0.000
Z95.0 Presence of cardiac pacemaker
0.743 0.257 0.000
B15-B19 Viral hepatitis
0.742 0.258 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.742 0.258 0.000
Q50-Q56 Congenital malformations of genital organs
0.741 0.259 0.000
R47-R49 Symptoms and signs involving speech and voice
0.741 0.259 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.741 0.259 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.740 0.259 0.000
A41 Other septicaemia
0.739 0.261 0.000
R54 Senility
0.738 0.262 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.736 0.264 0.000
M31 Other necrotising vasculopathies
0.736 0.264 0.000
B07 Viral warts
0.736 0.264 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.734 0.266 0.000
R46 Symptoms and signs involving appearance and behaviour
0.734 0.266 0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified
0.734 0.266 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.734 0.266 0.000
I25.3 Aneurysm of heart
0.732 0.268 0.000
T79-T79 Certain early complications of trauma
0.732 0.268 0.000
I45.3 Trifascicular block
0.730 0.269 0.000
S01.8 Open wound of other parts of head
0.728 0.272 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.728 0.272 0.000
R68 Other general symptoms and signs
0.725 0.275 0.000
R63.1 Polydipsia
0.724 0.276 0.000
I45.5 Other specified heart block
0.724 0.276 0.000
I31.3 Pericardial effusion (noninflammatory)
0.724 0.276 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.724 0.276 0.000
I42.9 Cardiomyopathy, unspecified
0.723 0.277 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.723 0.277 0.000
I21.9 Acute myocardial infarction, unspecified
0.722 0.278 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.722 0.278 0.000
N35 Urethral stricture
0.722 0.278 0.000
S01.9 Open wound of head, part unspecified
0.718 0.282 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.718 0.282 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M80-M85 Disorders of bone density and structure
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I30 Acute pericarditis
0.717 0.283 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.717 0.283 0.000
R62 Lack of expected normal physiological development
0.717 0.283 0.000
R64 Cachexia
0.717 0.283 0.000
R58 Haemorrhage, not elsewhere classified
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.716 0.284 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.716 0.284 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.715 0.284 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.715 0.285 0.000
R42 Dizziness and giddiness
0.715 0.285 0.000
N37 Urethral disorders in diseases classified elsewhere
0.715 0.285 0.000
N34 Urethritis and urethral syndrome
0.715 0.285 0.000
N33 Bladder disorders in diseases classified elsewhere
0.715 0.285 0.000
I95.8 Other hypotension
0.715 0.285 0.000
I95.0 Idiopathic hypotension
0.715 0.285 0.000
I44.2 Atrioventricular block, complete
0.714 0.286 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.714 0.286 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.713 0.287 0.000
S42.3 Fracture of shaft of humerus
0.712 0.287 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.712 0.288 0.000
E10.9 Without complications
0.712 0.288 0.000
Q23 Congenital malformations of aortic and mitral valves
0.711 0.289 0.000
S42.4 Fracture of lower end of humerus
0.711 0.289 0.000
R50.2 Drug-induced fever
0.710 0.289 0.000
R50.1 Persistent fever
0.710 0.289 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.710 0.290 0.000
S08 Traumatic amputation of part of head
0.710 0.290 0.000
S07 Crushing injury of head
0.710 0.290 0.000
S05 Injury of eye and orbit
0.710 0.290 0.000
S04 Injury of cranial nerves
0.710 0.290 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.710 0.290 0.000
M40-M43 Deforming dorsopathies
0.709 0.290 0.000
I20.1 Angina pectoris with documented spasm
0.709 0.291 0.000
N32.0 Bladder-neck obstruction
0.709 0.291 0.000
I25.6 Silent myocardial ischaemia
0.709 0.291 0.000
I25.4 Coronary artery aneurysm
0.709 0.291 0.000
I08 Multiple valve diseases
0.708 0.291 0.000
R33 Retention of urine
0.708 0.292 0.000
S42.10 Fracture of scapula (closed)
0.708 0.292 0.000
R45 Symptoms and signs involving emotional state
0.708 0.292 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.708 0.292 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.708 0.292 0.000
S48 Traumatic amputation of shoulder and upper arm
0.708 0.292 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.708 0.292 0.000
S44 Injury of nerves at shoulder and upper arm level
0.708 0.292 0.000
S41 Open wound of shoulder and upper arm
0.708 0.292 0.000
S47 Crushing injury of shoulder and upper arm
0.708 0.292 0.000
N17-N19 Renal failure
0.708 0.292 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.707 0.293 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.707 0.293 0.000
N48 Other disorders of penis
0.707 0.293 0.000
N30.2 Other chronic cystitis
0.707 0.293 0.000
Q00-Q07 Congenital malformations of the nervous system
0.706 0.294 0.000
Chapter XXII Codes for special purposes
0.705 0.294 0.000
S70-S79 Injuries to the hip and thigh
0.705 0.295 0.000
M00-M03 Infectious arthropathies
0.705 0.295 0.000
I99 Other and unspecified disorders of circulatory system
0.704 0.296 0.000
S00.7 Multiple superficial injuries of head
0.703 0.296 0.000
S00.5 Superficial injury of lip and oral cavity
0.703 0.296 0.000
S00.4 Superficial injury of ear
0.703 0.296 0.000
S00.3 Superficial injury of nose
0.703 0.296 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.703 0.296 0.000
S81 Open wound of lower leg
0.702 0.298 0.000
T70 Effects of air pressure and water pressure
0.702 0.298 0.000
Y40 Systemic antibiotics
0.701 0.298 0.000
I49.9 Cardiac arrhythmia, unspecified
0.701 0.299 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.701 0.299 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.701 0.299 0.000
N46 Male infertility
0.701 0.299 0.000
N44 Torsion of testis
0.701 0.299 0.000
R32 Unspecified urinary incontinence
0.701 0.299 0.000
T78 Adverse effects, not elsewhere classified
0.701 0.299 0.000
E16 Other disorders of pancreatic internal secretion
0.699 0.301 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.699 0.301 0.000
M21.1 Varus deformity, not elsewhere classified
0.699 0.301 0.000
I49.2 Junctional premature depolarisation
0.699 0.301 0.000
I49.1 Atrial premature depolarisation
0.698 0.302 0.000
B00 Herpesviral [herpes simplex] infections
0.697 0.303 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.696 0.304 0.000
I78.0 Hereditary haemorrhagic telangiectasia
0.696 0.304 0.000
D86.8 Sarcoidosis of other and combined sites
0.696 0.304 0.000
S00.0 Superficial injury of scalp
0.694 0.306 0.000
N39.2 Orthostatic proteinuria, unspecified
0.694 0.306 0.000
N39.1 Persistent proteinuria, unspecified
0.694 0.306 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.693 0.307 0.000
N15 Other renal tubulo-interstitial diseases
0.693 0.307 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.693 0.307 0.000
N11 Chronic tubulo-interstitial nephritis
0.693 0.307 0.000
N10 Acute tubulo-interstitial nephritis
0.693 0.307 0.000
I10-I15 Hypertensive diseases
0.693 0.307 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.692 0.307 0.000
S90-S99 Injuries to the ankle and foot
0.692 0.307 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.692 0.308 0.000
M45-M49 Spondylopathies
0.692 0.308 0.000
D86.9 Sarcoidosis, unspecified
0.691 0.309 0.000
B01 Varicella [chickenpox]
0.691 0.309 0.000
I49.4 Other and unspecified premature depolarisation
0.690 0.310 0.000
R34 Anuria and oliguria
0.690 0.310 0.000
S82.8 Fractures of other parts of lower leg
0.689 0.311 0.000
I44.1 Atrioventricular block, second degree
0.689 0.311 0.000
Q21.1 Atrial septal defect
0.689 0.311 0.000
R00 Abnormalities of heart beat
0.688 0.312 0.000
W00-W19 Falls
0.687 0.313 0.000
E78.5 Hyperlipidaemia, unspecified
0.686 0.314 0.000
R43 Disturbances of smell and taste
0.685 0.315 0.000
M25.78 Osteophyte (Other)
0.685 0.315 0.000
N13 Obstructive and reflux uropathy
0.684 0.316 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.684 0.316 0.000
R63.8 Other symptoms and signs concerning food and fluid intake
0.683 0.317 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.683 0.317 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.683 0.317 0.000
R60 Oedema, not elsewhere classified
0.682 0.318 0.000
E22 Hyperfunction of pituitary gland
0.682 0.318 0.000
B25-B34 Other viral diseases
0.681 0.319 0.000
M15-M19 Arthrosis
0.680 0.320 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.680 0.320 0.000
S06 Intracranial injury
0.679 0.320 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.679 0.321 0.000
Q80-Q89 Other congenital malformations
0.679 0.321 0.000
Q35-Q37 Cleft lip and cleft palate
0.679 0.321 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.679 0.321 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.679 0.321 0.000
I72.3 Aneurysm of iliac artery
0.679 0.321 0.000
I38 Endocarditis, valve unspecified
0.679 0.321 0.000
S42.9 Fracture of shoulder girdle, part unspecified
0.679 0.321 0.000
S42.8 Fracture of other parts of shoulder and upper arm
0.679 0.321 0.000
S42.7 Multiple fractures of clavicle, scapula and humerus
0.679 0.321 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.679 0.321 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.678 0.322 0.000
R59.1 Generalised enlarged lymph nodes
0.678 0.322 0.000
B35 Dermatophytosis
0.678 0.322 0.000
S01.5 Open wound of lip and oral cavity
0.677 0.323 0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified
0.677 0.323 0.000
Q60-Q64 Congenital malformations of the urinary system
0.677 0.323 0.000
R10 Abdominal and pelvic pain
0.676 0.324 0.000
I77.8 Other specified disorders of arteries and arterioles
0.676 0.324 0.000
I77.5 Necrosis of artery
0.676 0.324 0.000
I77.4 Coeliac artery compression syndrome
0.676 0.324 0.000
I77.3 Arterial fibromuscular dysplasia
0.676 0.324 0.000
I77.2 Rupture of artery
0.676 0.324 0.000
I77.0 Arteriovenous fistula, acquired
0.676 0.324 0.000
B99-B99 Other infectious diseases
0.675 0.325 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.675 0.325 0.000
B65-B83 Helminthiases
0.675 0.325 0.000
B50-B64 Protozoal diseases
0.675 0.325 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.675 0.325 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.675 0.325 0.000
A80-A89 Viral infections of the central nervous system
0.675 0.325 0.000
A75-A79 Rickettsioses
0.675 0.325 0.000
A70-A74 Other diseases caused by chlamydiae
0.675 0.325 0.000
A65-A69 Other spirochaetal diseases
0.675 0.325 0.000
A20-A28 Certain zoonotic bacterial diseases
0.675 0.325 0.000
A15-A19 Tuberculosis
0.675 0.325 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.675 0.325 0.000
R36 Urethral discharge
0.675 0.325 0.000
E83.5 Disorders of calcium metabolism
0.675 0.325 0.000
I24 Other acute ischaemic heart diseases
0.674 0.326 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.673 0.327 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.673 0.327 0.000
N32.4 Rupture of bladder, nontraumatic
0.672 0.328 0.000
N32.2 Vesical fistula, not elsewhere classified
0.672 0.328 0.000
A41.9 Septicaemia, unspecified
0.671 0.329 0.000
M77 Other enthesopathies
0.671 0.329 0.000
S86 Injury of muscle and tendon at lower leg level
0.671 0.329 0.000
R10.3 Pain localised to other parts of lower abdomen
0.670 0.330 0.000
N30.8 Other cystitis
0.670 0.330 0.000
I44.3 Other and unspecified atrioventricular block
0.670 0.330 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.669 0.331 0.000
I45.8 Other specified conduction disorders
0.667 0.333 0.000
I45.4 Nonspecific intraventricular block
0.667 0.333 0.000
I45.2 Bifascicular block
0.667 0.333 0.000
I45.0 Right fascicular block
0.667 0.333 0.000
I72.4 Aneurysm of artery of lower extremity
0.666 0.334 0.000
S12 Fracture of neck
0.666 0.334 0.000
I72.8 Aneurysm of other specified arteries
0.663 0.337 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.662 0.337 0.000
T91 Sequelae of injuries of neck and trunk
0.661 0.339 0.000
W20-W49 Exposure to inanimate mechanical forces
0.661 0.339 0.000
I21.4 Acute subendocardial myocardial infarction
0.660 0.340 0.000
S60-S69 Injuries to the wrist and hand
0.660 0.340 0.000
M23.8 Other internal derangements of knee
0.659 0.341 0.000
I73.8 Other specified peripheral vascular diseases
0.658 0.342 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.658 0.342 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.657 0.342 0.000
I47.0 Reentry ventricular arrhythmia
0.657 0.342 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.658 0.342 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.657 0.343 0.000
E66 Obesity
0.657 0.343 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.656 0.343 0.000
E40-E46 Malnutrition
0.656 0.344 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.656 0.344 0.000
N19 Unspecified renal failure
0.656 0.344 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.655 0.345 0.000
M21.3 Wrist or foot drop (acquired)
0.655 0.345 0.000
N36 Other disorders of urethra
0.655 0.345 0.000
Z95.4 Presence of other heart-valve replacement
0.655 0.345 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.654 0.346 0.000
M33 Dermatopolymyositis
0.654 0.346 0.000
M32 Systemic lupus erythematosus
0.654 0.346 0.000
M30 Polyarteritis nodosa and related conditions
0.654 0.346 0.000
N30.3 Trigonitis
0.653 0.347 0.000
H90-H95 Other disorders of ear
0.650 0.349 0.000
T68 Hypothermia
0.649 0.351 0.000
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess
0.649 0.351 0.000
I45.6 Preexcitation syndrome
0.648 0.351 0.000
D55-D59 Haemolytic anaemias
0.648 0.351 0.000
M21.0 Valgus deformity, not elsewhere classified
0.647 0.353 0.000
Y52 Agents primarily affecting the cardiovascular system
0.646 0.354 0.000
I70 Atherosclerosis
0.645 0.355 0.000
S01.7 Multiple open wounds of head
0.645 0.355 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.645 0.355 0.000
E88 Other metabolic disorders
0.643 0.357 0.000
I44.6 Other and unspecified fascicular block
0.642 0.357 0.000
I44.5 Left posterior fascicular block
0.642 0.357 0.000
I44.4 Left anterior fascicular block
0.642 0.357 0.000
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle
0.642 0.358 0.000
S43.6 Sprain and strain of sternoclavicular joint
0.642 0.358 0.000
S43.5 Sprain and strain of acromioclavicular joint
0.642 0.358 0.000
S43.4 Sprain and strain of shoulder joint
0.642 0.358 0.000
S43.3 Dislocation of other and unspecified parts of shoulder girdle
0.642 0.358 0.000
S43.2 Dislocation of sternoclavicular joint
0.642 0.358 0.000
S43.1 Dislocation of acromioclavicular joint
0.642 0.358 0.000
S42.21 Fracture of upper end of humerus (open)
0.642 0.358 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.642 0.358 0.000
M72 Fibroblastic disorders
0.641 0.359 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.640 0.359 0.000
R63.6 Insufficient intake of food and water due to self neglect
0.640 0.360 0.000
R63.5 Abnormal weight gain
0.640 0.360 0.000
R63.3 Feeding difficulties and mismanagement
0.640 0.360 0.000
R63.2 Polyphagia
0.640 0.360 0.000
H80-H83 Diseases of inner ear
0.639 0.361 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.638 0.362 0.000
M25.8 Other specified joint disorders
0.637 0.363 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.636 0.364 0.000
S82.80 Fractures of other parts of lower leg (closed)
0.636 0.364 0.000
X60-X84 Intentional self-harm
0.636 0.364 0.000
R56 Convulsions, not elsewhere classified
0.636 0.364 0.000
M62 Other disorders of muscle
0.634 0.366 0.000
N31.1 Reflex neuropathic bladder, not elsewhere classified
0.634 0.366 0.000
N31.0 Uninhibited neuropathic bladder, not elsewhere classified
0.634 0.366 0.000
R41.2 Retrograde amnesia
0.633 0.367 0.000
R41.1 Anterograde amnesia
0.633 0.367 0.000
I31.8 Other specified diseases of pericardium
0.633 0.367 0.000
I31.2 Haemopericardium, not elsewhere classified
0.633 0.367 0.000
I31.1 Chronic constrictive pericarditis
0.633 0.367 0.000
I31.0 Chronic adhesive pericarditis
0.633 0.367 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.633 0.367 0.000
M34.1 CR(E)ST syndrome
0.632 0.368 0.000
E10.5 With peripheral circulatory complications
0.632 0.368 0.000
Q21.0 Ventricular septal defect
0.632 0.368 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.630 0.370 0.000
N64 Other disorders of breast
0.630 0.370 0.000
D64 Other anaemias
0.629 0.371 0.000
I45.9 Conduction disorder, unspecified
0.629 0.371 0.000
I07 Rheumatic tricuspid valve diseases
0.628 0.372 0.000
M22 Disorders of patella
0.627 0.373 0.000
B44 Aspergillosis
0.627 0.373 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.626 0.374 0.000
N42.9 Disorder of prostate, unspecified
0.626 0.374 0.000
I20.8 Other forms of angina pectoris
0.626 0.374 0.000
E50-E64 Other nutritional deficiencies
0.625 0.375 0.000
R01.0 Benign and innocent cardiac murmurs
0.625 0.375 0.000
M96.0 Pseudarthrosis after fusion or arthrodesis
0.625 0.375 0.000
Chapter X Diseases of the respiratory system
0.623 0.377 0.000
I44.7 Left bundle-branch block, unspecified
0.623 0.377 0.000
Q28 Other congenital malformations of circulatory system
0.623 0.377 0.000
Q27 Other congenital malformations of peripheral vascular system
0.623 0.377 0.000
Q26 Congenital malformations of great veins
0.623 0.377 0.000
Q25 Congenital malformations of great arteries
0.623 0.377 0.000
Q24 Other congenital malformations of heart
0.623 0.377 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.623 0.377 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.623 0.377 0.000
M34.9 Systemic sclerosis, unspecified
0.622 0.377 0.000
I95.2 Hypotension due to drugs
0.621 0.379 0.000
R40.2 Coma, unspecified
0.621 0.379 0.000
E16.2 Hypoglycaemia, unspecified
0.621 0.379 0.000
T75 Effects of other external causes
0.620 0.380 0.000
T74 Maltreatment syndromes
0.620 0.380 0.000
T73 Effects of other deprivation
0.620 0.380 0.000
T69 Other effects of reduced temperature
0.620 0.380 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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