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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs113203074
log Bayes Factor = 13.6298
Chromosome 6   position 31,387,875  (GRCh37) Explore rs113203074 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
C44 Other malignant neoplasms of skin
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
1.000 0.000 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.999 0.001 0.000
Chapter XI Diseases of the digestive system
0.999 0.001 0.000
K50-K52 Noninfective enteritis and colitis
0.999 0.001 0.000
K50 Crohn's disease [regional enteritis]
0.999 0.001 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.999 0.001 0.000
K50.9 Crohn's disease, unspecified
0.997 0.003 0.000
Chapter XX External causes of morbidity and mortality
0.997 0.003 0.000
S60-S69 Injuries to the wrist and hand
0.997 0.003 0.000
C44.3 Skin of other and unspecified parts of face
0.997 0.003 0.000
K70-K77 Diseases of liver
0.995 0.005 0.000
S61 Open wound of wrist and hand
0.994 0.006 0.000
C44.1 Skin of eyelid, including canthus
0.992 0.008 0.000
S70-S79 Injuries to the hip and thigh
0.992 0.008 0.000
S61.0 Open wound of finger(s) without damage to nail
0.978 0.022 0.000
D10-D36 Benign neoplasms
0.977 0.023 0.000
K74 Fibrosis and cirrhosis of liver
0.975 0.025 0.000
C44.4 Skin of scalp and neck
0.974 0.026 0.000
S72 Fracture of femur
0.974 0.026 0.000
I30-I52 Other forms of heart disease
0.973 0.027 0.000
Chapter IX Diseases of the circulatory system
0.972 0.028 0.000
D23 Other benign neoplasms of skin
0.968 0.032 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.962 0.038 0.000
I35 Nonrheumatic aortic valve disorders
0.960 0.040 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.952 0.048 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.948 0.052 0.000
K72 Hepatic failure, not elsewhere classified
0.945 0.055 0.000
K50.0 Crohn's disease of small intestine
0.939 0.061 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.933 0.067 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.932 0.068 0.000
S90-S99 Injuries to the ankle and foot
0.931 0.069 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.918 0.082 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.917 0.083 0.000
D23.1 Skin of eyelid, including canthus
0.916 0.084 0.000
S72.1 Pertrochanteric fracture
0.909 0.091 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.908 0.092 0.000
L40-L45 Papulosquamous disorders
0.908 0.092 0.000
K50.1 Crohn's disease of large intestine
0.908 0.092 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.906 0.094 0.000
I34 Nonrheumatic mitral valve disorders
0.906 0.094 0.000
K74.0 Hepatic fibrosis
0.903 0.097 0.000
S61.8 Open wound of other parts of wrist and hand
0.897 0.103 0.000
I42 Cardiomyopathy
0.894 0.106 0.000
S50-S59 Injuries to the elbow and forearm
0.894 0.106 0.000
D18 Haemangioma and lymphangioma, any site
0.887 0.113 0.000
C64-C68 Malignant neoplasms of urinary tract
0.885 0.115 0.000
S72.3 Fracture of shaft of femur
0.882 0.118 0.000
I44 Atrioventricular and left bundle-branch block
0.880 0.120 0.000
K70 Alcoholic liver disease
0.877 0.123 0.000
K72.9 Hepatic failure, unspecified
0.875 0.125 0.000
K51 Ulcerative colitis
0.874 0.126 0.000
I35.0 Aortic (valve) stenosis
0.870 0.130 0.000
L40 Psoriasis
0.866 0.134 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.866 0.134 0.000
S70 Superficial injury of hip and thigh
0.865 0.135 0.000
S72.10 Pertrochanteric fracture (closed)
0.863 0.137 0.000
I46 Cardiac arrest
0.862 0.138 0.000
S20-S29 Injuries to the thorax
0.862 0.138 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.858 0.142 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.858 0.142 0.000
K74.6 Other and unspecified cirrhosis of liver
0.858 0.142 0.000
I34.0 Mitral (valve) insufficiency
0.857 0.143 0.000
W20-W49 Exposure to inanimate mechanical forces
0.857 0.143 0.000
I44.0 Atrioventricular block, first degree
0.853 0.147 0.000
Chapter VII Diseases of the eye and adnexa
0.851 0.149 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.850 0.150 0.000
S61.1 Open wound of finger(s) with damage to nail
0.850 0.150 0.000
D23.5 Skin of trunk
0.849 0.151 0.000
D36 Benign neoplasm of other and unspecified sites
0.846 0.154 0.000
D30 Benign neoplasm of urinary organs
0.846 0.154 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.844 0.156 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.844 0.156 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.841 0.159 0.000
Chapter XXII Codes for special purposes
0.836 0.164 0.000
S52 Fracture of forearm
0.836 0.164 0.000
C44.2 Skin of ear and external auricular canal
0.834 0.166 0.000
L40.9 Psoriasis, unspecified
0.834 0.166 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.831 0.169 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.830 0.170 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.830 0.170 0.000
L50-L54 Urticaria and erythema
0.829 0.171 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.828 0.172 0.000
S10-S19 Injuries to the neck
0.828 0.172 0.000
W00-W19 Falls
0.826 0.174 0.000
T66-T78 Other and unspecified effects of external causes
0.824 0.176 0.000
S80-S89 Injuries to the knee and lower leg
0.822 0.178 0.000
D18.0 Haemangioma, any site
0.822 0.178 0.000
T92 Sequelae of injuries of upper limb
0.821 0.178 0.000
K74.3 Primary biliary cirrhosis
0.821 0.179 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.821 0.179 0.000
I47 Paroxysmal tachycardia
0.820 0.180 0.000
S64 Injury of nerves at wrist and hand level
0.819 0.181 0.000
I36 Nonrheumatic tricuspid valve disorders
0.818 0.182 0.000
S72.0 Fracture of neck of femur
0.817 0.183 0.000
Y57 Other and unspecified drugs and medicaments
0.816 0.184 0.000
S72.30 Fracture of shaft of femur (closed)
0.815 0.185 0.000
V20-V29 Motorcycle rider injured in transport accident
0.815 0.185 0.000
C44.6 Skin of upper limb, including shoulder
0.813 0.187 0.000
S00-S09 Injuries to the head
0.813 0.187 0.000
S67 Crushing injury of wrist and hand
0.812 0.188 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.811 0.189 0.000
I35.8 Other aortic valve disorders
0.810 0.190 0.000
K72.0 Acute and subacute hepatic failure
0.810 0.190 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.806 0.194 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.806 0.194 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.805 0.195 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.804 0.196 0.000
S92 Fracture of foot, except ankle
0.802 0.198 0.000
W50-W64 Exposure to animate mechanical forces
0.801 0.199 0.000
E83.1 Disorders of iron metabolism
0.800 0.200 0.000
D10 Benign neoplasm of mouth and pharynx
0.798 0.202 0.000
D23.7 Skin of lower limb, including hip
0.798 0.202 0.000
S40-S49 Injuries to the shoulder and upper arm
0.798 0.202 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.797 0.203 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.797 0.203 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.795 0.205 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.795 0.205 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.794 0.206 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.792 0.208 0.000
V80-V89 Other land transport accidents
0.791 0.209 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.791 0.209 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.790 0.210 0.000
I35.9 Aortic valve disorder, unspecified
0.790 0.210 0.000
C44.9 Malignant neoplasm of skin, unspecified
0.789 0.211 0.000
D23.6 Skin of upper limb, including shoulder
0.789 0.211 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.788 0.212 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.787 0.213 0.000
Y42.7 Androgens and anabolic congeners
0.787 0.213 0.000
K51.2 Ulcerative (chronic) proctitis
0.786 0.214 0.000
D32 Benign neoplasm of meninges
0.785 0.215 0.000
I35.1 Aortic (valve) insufficiency
0.784 0.216 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.782 0.218 0.000
I42.9 Cardiomyopathy, unspecified
0.780 0.219 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.779 0.221 0.000
S60 Superficial injury of wrist and hand
0.777 0.223 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.775 0.225 0.000
S70.9 Superficial injury of hip and thigh, unspecified
0.774 0.226 0.000
D23.3 Skin of other and unspecified parts of face
0.774 0.226 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.773 0.227 0.000
T87 Complications peculiar to reattachment and amputation
0.773 0.227 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.773 0.227 0.000
S02 Fracture of skull and facial bones
0.771 0.229 0.000
I33 Acute and subacute endocarditis
0.768 0.232 0.000
D16 Benign neoplasm of bone and articular cartilage
0.767 0.233 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.766 0.234 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.765 0.235 0.000
S99 Other and unspecified injuries of ankle and foot
0.763 0.237 0.000
S82 Fracture of lower leg, including ankle
0.763 0.237 0.000
H43-H45 Disorders of vitreous body and globe
0.762 0.238 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.761 0.239 0.000
D36.7 Other specified sites
0.760 0.240 0.000
C67 Malignant neoplasm of bladder
0.759 0.241 0.000
K70.4 Alcoholic hepatic failure
0.759 0.241 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.757 0.243 0.000
Y48 Anaesthetics and therapeutic gases
0.757 0.243 0.000
I30 Acute pericarditis
0.756 0.244 0.000
C50-C50 Malignant neoplasm of breast
0.754 0.246 0.000
H40-H42 Glaucoma
0.754 0.246 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.753 0.247 0.000
D30.3 Bladder
0.752 0.248 0.000
I46.0 Cardiac arrest with successful resuscitation
0.752 0.248 0.000
S71 Open wound of hip and thigh
0.751 0.248 0.000
V10-V19 Pedal cyclist injured in transport accident
0.751 0.249 0.000
E83 Disorders of mineral metabolism
0.750 0.250 0.000
L85 Other epidermal thickening
0.749 0.251 0.000
D24 Benign neoplasm of breast
0.749 0.251 0.000
I05-I09 Chronic rheumatic heart diseases
0.748 0.252 0.000
X20-X29 Contact with venomous animals and plants
0.748 0.252 0.000
S90 Superficial injury of ankle and foot
0.747 0.253 0.000
V40-V49 Car occupant injured in transport accident
0.746 0.254 0.000
D37.5 Rectum
0.746 0.254 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.746 0.254 0.000
E70-E90 Metabolic disorders
0.746 0.254 0.000
S22.3 Fracture of rib
0.744 0.256 0.000
K51.8 Other ulcerative colitis
0.743 0.257 0.000
S52.6 Fracture of lower end of both ulna and radius
0.742 0.258 0.000
K74.5 Biliary cirrhosis, unspecified
0.742 0.258 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.740 0.260 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.735 0.265 0.000
D23.4 Skin of scalp and neck
0.733 0.267 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.732 0.268 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.732 0.268 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.730 0.270 0.000
Chapter V Mental and behavioural disorders
0.730 0.270 0.000
L43 Lichen planus
0.729 0.271 0.000
Chapter VI Diseases of the nervous system
0.728 0.272 0.000
L53 Other erythematous conditions
0.728 0.272 0.000
D23.9 Skin, unspecified
0.728 0.272 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.726 0.273 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.726 0.274 0.000
T86 Failure and rejection of transplanted organs and tissues
0.725 0.275 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.723 0.277 0.000
Y52 Agents primarily affecting the cardiovascular system
0.723 0.277 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.723 0.277 0.000
L40.0 Psoriasis vulgaris
0.723 0.277 0.000
S61.7 Multiple open wounds of wrist and hand
0.720 0.280 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.720 0.280 0.000
C66 Malignant neoplasm of ureter
0.718 0.281 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.718 0.282 0.000
D37.4 Colon
0.718 0.282 0.000
K70.0 Alcoholic fatty liver
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C44.8 Overlapping lesion of skin
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.716 0.284 0.000
G35 Multiple sclerosis
0.716 0.284 0.000
Q80-Q89 Other congenital malformations
0.715 0.284 0.000
S50 Superficial injury of forearm
0.715 0.285 0.000
Q23 Congenital malformations of aortic and mitral valves
0.715 0.285 0.000
Y35-Y36 Legal intervention and operations of war
0.715 0.285 0.000
Y10-Y34 Event of undetermined intent
0.715 0.285 0.000
Y00-Y09 Assault
0.715 0.285 0.000
X85-X99 Assault
0.715 0.285 0.000
X50-X57 Overexertion, travel and privation
0.715 0.285 0.000
X30-X39 Exposure to forces of nature
0.715 0.285 0.000
X10-X19 Contact with heat and hot substances
0.715 0.285 0.000
X00-X09 Exposure to smoke, fire and flames
0.715 0.285 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.715 0.285 0.000
W75-W84 Other accidental threats to breathing
0.715 0.285 0.000
W65-W74 Accidental drowning and submersion
0.715 0.285 0.000
V98-V99 Other and unspecified transport accidents
0.715 0.285 0.000
V95-V97 Air and space transport accidents
0.715 0.285 0.000
V90-V94 Water transport accidents
0.715 0.285 0.000
V70-V79 Bus occupant injured in transport accident
0.715 0.285 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.715 0.285 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.715 0.285 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.715 0.285 0.000
V01-V09 Pedestrian injured in transport accident
0.715 0.285 0.000
S65 Injury of blood vessels at wrist and hand level
0.715 0.285 0.000
H20 Iridocyclitis
0.714 0.285 0.000
S79 Other and unspecified injuries of hip and thigh
0.714 0.286 0.000
Q28 Other congenital malformations of circulatory system
0.714 0.286 0.000
K77 Liver disorders in diseases classified elsewhere
0.713 0.287 0.000
K71 Toxic liver disease
0.713 0.287 0.000
Y57.9 Drug or medicament, unspecified
0.713 0.287 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.712 0.288 0.000
S78 Traumatic amputation of hip and thigh
0.711 0.289 0.000
S77 Crushing injury of hip and thigh
0.711 0.289 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.711 0.289 0.000
S75 Injury of blood vessels at hip and thigh level
0.711 0.289 0.000
S74 Injury of nerves at hip and thigh level
0.711 0.289 0.000
L89 Decubitus ulcer
0.711 0.289 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.710 0.290 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.710 0.290 0.000
S22.30 Fracture of rib (closed)
0.708 0.292 0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.708 0.292 0.000
T92.9 Sequelae of unspecified injury of upper limb
0.707 0.292 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.707 0.293 0.000
K50.8 Other Crohn's disease
0.706 0.294 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.706 0.294 0.000
T91 Sequelae of injuries of neck and trunk
0.706 0.294 0.000
K70.3 Alcoholic cirrhosis of liver
0.705 0.294 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.705 0.295 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.704 0.296 0.000
S72.00 Fracture of neck of femur (closed)
0.704 0.296 0.000
S02.8 Fractures of other skull and facial bones
0.702 0.298 0.000
W22 Striking against or struck by other objects
0.701 0.299 0.000
D31 Benign neoplasm of eye and adnexa
0.701 0.299 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.701 0.299 0.000
D19 Benign neoplasm of mesothelial tissue
0.701 0.299 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.701 0.299 0.000
S12 Fracture of neck
0.701 0.299 0.000
I42.0 Dilated cardiomyopathy
0.700 0.300 0.000
D26 Other benign neoplasms of uterus
0.700 0.300 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.699 0.300 0.000
K74.4 Secondary biliary cirrhosis
0.699 0.301 0.000
K74.2 Hepatic fibrosis with hepatic sclerosis
0.699 0.301 0.000
K74.1 Hepatic sclerosis
0.699 0.301 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.699 0.301 0.000
S72.9 Fracture of femur, part unspecified
0.698 0.301 0.000
S72.8 Fractures of other parts of femur
0.698 0.301 0.000
S72.7 Multiple fractures of femur
0.698 0.301 0.000
S72.4 Fracture of lower end of femur
0.698 0.301 0.000
S72.2 Subtrochanteric fracture
0.698 0.301 0.000
D21.1 Connective and other soft tissue of upper limb, including shoulder
0.698 0.302 0.000
H43 Disorders of vitreous body
0.698 0.302 0.000
I52 Other heart disorders in diseases classified elsewhere
0.697 0.303 0.000
I48 Atrial fibrillation and flutter
0.697 0.303 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.697 0.303 0.000
I41 Myocarditis in diseases classified elsewhere
0.697 0.303 0.000
I40 Acute myocarditis
0.697 0.303 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.697 0.303 0.000
I32 Pericarditis in diseases classified elsewhere
0.697 0.303 0.000
T78 Adverse effects, not elsewhere classified
0.697 0.303 0.000
I00-I02 Acute rheumatic fever
0.697 0.303 0.000
D29 Benign neoplasm of male genital organs
0.696 0.304 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.694 0.306 0.000
I44.1 Atrioventricular block, second degree
0.694 0.306 0.000
S52.4 Fracture of shafts of both ulna and radius
0.692 0.308 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.692 0.308 0.000
I37 Pulmonary valve disorders
0.691 0.309 0.000
Y59 Other and unspecified vaccines and biological substances
0.690 0.310 0.000
Y58 Bacterial vaccines
0.690 0.310 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.690 0.310 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.690 0.310 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.690 0.310 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.690 0.310 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.690 0.310 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.690 0.310 0.000
K73 Chronic hepatitis, not elsewhere classified
0.689 0.310 0.000
S91 Open wound of ankle and foot
0.689 0.310 0.000
W29 Contact with other powered hand tools and household machinery
0.689 0.311 0.000
I44.3 Other and unspecified atrioventricular block
0.689 0.311 0.000
D41.4 Bladder
0.688 0.312 0.000
I46.9 Cardiac arrest, unspecified
0.687 0.313 0.000
T23 Burn and corrosion of wrist and hand
0.687 0.313 0.000
H55-H59 Other disorders of eye and adnexa
0.687 0.313 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.686 0.314 0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van
0.684 0.315 0.000
H40 Glaucoma
0.684 0.316 0.000
T88.4 Failed or difficult intubation
0.683 0.317 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.683 0.317 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.683 0.317 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.683 0.317 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.683 0.317 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.682 0.318 0.000
L10-L14 Bullous disorders
0.680 0.320 0.000
X60-X84 Intentional self-harm
0.679 0.321 0.000
S67.0 Crushing injury of thumb and other finger(s)
0.679 0.321 0.000
Y40 Systemic antibiotics
0.679 0.321 0.000
I42.8 Other cardiomyopathies
0.679 0.321 0.000
C44.7 Skin of lower limb, including hip
0.678 0.322 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.678 0.322 0.000
K72.1 Chronic hepatic failure
0.678 0.322 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.677 0.322 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.677 0.323 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.677 0.323 0.000
I42.2 Other hypertrophic cardiomyopathy
0.677 0.323 0.000
I71 Aortic aneurysm and dissection
0.677 0.323 0.000
D35.1 Parathyroid gland
0.676 0.324 0.000
S52.60 Fracture of lower end of both ulna and radius (closed)
0.675 0.325 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.675 0.325 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.674 0.326 0.000
Y45.1 Salicylates
0.673 0.327 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.672 0.328 0.000
S31 Open wound of abdomen, lower back and pelvis
0.672 0.328 0.000
S64.1 Injury of median nerve at wrist and hand level
0.671 0.329 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.670 0.330 0.000
Q00-Q07 Congenital malformations of the nervous system
0.669 0.331 0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft
0.668 0.332 0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract
0.668 0.332 0.000
T83.2 Mechanical complication of graft of urinary organ
0.668 0.332 0.000
D43.2 Brain, unspecified
0.668 0.332 0.000
W18 Other fall on same level
0.668 0.332 0.000
T93 Sequelae of injuries of lower limb
0.668 0.332 0.000
S98 Traumatic amputation of ankle and foot
0.667 0.332 0.000
S97 Crushing injury of ankle and foot
0.667 0.332 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.667 0.332 0.000
S95 Injury of blood vessels at ankle and foot level
0.667 0.332 0.000
S94 Injury of nerves at ankle and foot level
0.667 0.332 0.000
H18 Other disorders of cornea
0.665 0.335 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.665 0.335 0.000
W13 Fall from, out of or through building or structure
0.665 0.335 0.000
D45 Polycythaemia vera
0.664 0.336 0.000
W10 Fall on and from stairs and steps
0.664 0.336 0.000
C65 Malignant neoplasm of renal pelvis
0.664 0.336 0.000
I47.2 Ventricular tachycardia
0.664 0.336 0.000
S05 Injury of eye and orbit
0.663 0.337 0.000
D48.1 Connective and other soft tissue
0.663 0.337 0.000
S92.3 Fracture of metatarsal bone
0.662 0.338 0.000
D23.0 Skin of lip
0.661 0.339 0.000
I42.6 Alcoholic cardiomyopathy
0.660 0.340 0.000
D37.2 Small intestine
0.660 0.340 0.000
S52.0 Fracture of upper end of ulna
0.659 0.341 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.659 0.341 0.000
S82.5 Fracture of medial malleolus
0.659 0.341 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.657 0.343 0.000
Q35-Q37 Cleft lip and cleft palate
0.657 0.343 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.657 0.343 0.000
D37.9 Digestive organ, unspecified
0.657 0.343 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.657 0.343 0.000
D23.2 Skin of ear and external auricular canal
0.657 0.343 0.000
T85.2 Mechanical complication of intraocular lens
0.656 0.344 0.000
L81 Other disorders of pigmentation
0.656 0.344 0.000
Y44 Agents primarily affecting blood constituents
0.656 0.344 0.000
D10.1 Tongue
0.655 0.344 0.000
H21 Other disorders of iris and ciliary body
0.655 0.345 0.000
L53.9 Erythematous condition, unspecified
0.655 0.345 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.654 0.346 0.000
S02.80 Fractures of other skull and facial bones (closed)
0.652 0.348 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.652 0.348 0.000
S42 Fracture of shoulder and upper arm
0.652 0.348 0.000
S72.11 Pertrochanteric fracture (open)
0.652 0.348 0.000
S64.0 Injury of ulnar nerve at wrist and hand level
0.652 0.348 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.652 0.348 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.652 0.348 0.000
T98 Sequelae of other and unspecified effects of external causes
0.651 0.349 0.000
T95 Sequelae of burns, corrosions and frostbite
0.651 0.349 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.651 0.349 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.651 0.349 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.651 0.349 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.651 0.349 0.000
L44 Other papulosquamous disorders
0.651 0.349 0.000
L41 Parapsoriasis
0.651 0.349 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.651 0.349 0.000
L42 Pityriasis rosea
0.651 0.349 0.000
Y42.9 Other and unspecified hormone antagonists
0.650 0.350 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.650 0.350 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.650 0.350 0.000
Y42.4 Oral contraceptives
0.650 0.350 0.000
Y42.2 Antithyroid drugs
0.650 0.350 0.000
Y42.1 Thyroid hormones and substitutes
0.650 0.350 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.649 0.351 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.649 0.351 0.000
I44.6 Other and unspecified fascicular block
0.649 0.351 0.000
D43.0 Brain, supratentorial
0.648 0.352 0.000
D10.0 Lip
0.648 0.352 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.648 0.352 0.000
S92.0 Fracture of calcaneus
0.648 0.352 0.000
T92.1 Sequelae of fracture of arm
0.647 0.353 0.000
D48.0 Bone and articular cartilage
0.647 0.353 0.000
T90 Sequelae of injuries of head
0.646 0.354 0.000
W08 Fall involving other furniture
0.646 0.354 0.000
D48.5 Skin
0.645 0.355 0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified
0.644 0.356 0.000
S99.9 Unspecified injury of ankle and foot
0.643 0.357 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.643 0.357 0.000
D37.0 Lip, oral cavity and pharynx
0.642 0.358 0.000
S68 Traumatic amputation of wrist and hand
0.642 0.358 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.641 0.359 0.000
I42.5 Other restrictive cardiomyopathy
0.641 0.359 0.000
I42.4 Endocardial fibroelastosis
0.641 0.359 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.641 0.359 0.000
S59 Other and unspecified injuries of forearm
0.641 0.359 0.000
S58 Traumatic amputation of forearm
0.641 0.359 0.000
S57 Crushing injury of forearm
0.641 0.359 0.000
S56 Injury of muscle and tendon at forearm level
0.641 0.359 0.000
S55 Injury of blood vessels at forearm level
0.641 0.359 0.000
S54 Injury of nerves at forearm level
0.641 0.359 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.641 0.359 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.641 0.359 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.641 0.359 0.000
K75 Other inflammatory liver diseases
0.640 0.360 0.000
I45 Other conduction disorders
0.639 0.361 0.000
L89.1 Stage II decubitus ulcer
0.639 0.361 0.000
W44 Foreign body entering into or through eye or natural orifice
0.638 0.362 0.000
T17 Foreign body in respiratory tract
0.637 0.363 0.000
S82.4 Fracture of fibula alone
0.637 0.363 0.000
T20 Burn and corrosion of head and neck
0.637 0.363 0.000
F99-F99 Unspecified mental disorder
0.637 0.363 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.636 0.364 0.000
W20 Struck by thrown, projected or falling object
0.636 0.364 0.000
D18.1 Lymphangioma, any site
0.636 0.364 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.634 0.365 0.000
L85.9 Epidermal thickening, unspecified
0.634 0.366 0.000
S22.2 Fracture of sternum
0.634 0.366 0.000
T92.2 Sequelae of fracture at wrist and hand level
0.634 0.366 0.000
H20.9 Iridocyclitis, unspecified
0.634 0.366 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.634 0.366 0.000
S72.31 Fracture of shaft of femur (open)
0.632 0.368 0.000
S10 Superficial injury of neck
0.632 0.368 0.000
L50 Urticaria
0.632 0.368 0.000
S82.2 Fracture of shaft of tibia
0.632 0.368 0.000
Q23.1 Congenital insufficiency of aortic valve
0.632 0.368 0.000
I44.5 Left posterior fascicular block
0.631 0.369 0.000
I44.4 Left anterior fascicular block
0.631 0.369 0.000
L90 Atrophic disorders of skin
0.630 0.370 0.000
Q28.2 Arteriovenous malformation of cerebral vessels
0.630 0.370 0.000
C67.9 Bladder, unspecified
0.630 0.370 0.000
D32.0 Cerebral meninges
0.629 0.371 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.629 0.371 0.000
H43.1 Vitreous haemorrhage
0.629 0.371 0.000
K70.2 Alcoholic fibrosis and sclerosis of liver
0.629 0.371 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.628 0.372 0.000
E40-E46 Malnutrition
0.627 0.373 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.627 0.373 0.000
S52.8 Fracture of other parts of forearm
0.627 0.373 0.000
S69 Other and unspecified injuries of wrist and hand
0.626 0.374 0.000
D48.7 Other specified sites
0.625 0.375 0.000
I05 Rheumatic mitral valve diseases
0.625 0.375 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.625 0.375 0.000
S02.3 Fracture of orbital floor
0.624 0.376 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.624 0.376 0.000
Q50-Q56 Congenital malformations of genital organs
0.623 0.377 0.000
W50 Hit, struck, kicked, twisted, bitten or scratched by another person
0.623 0.377 0.000
Q60-Q64 Congenital malformations of the urinary system
0.622 0.378 0.000
C67.5 Bladder neck
0.622 0.378 0.000
I33.0 Acute and subacute infective endocarditis
0.622 0.378 0.000
W55 Bitten or struck by other mammals
0.621 0.379 0.000
L40.8 Other psoriasis
0.621 0.379 0.000
L40.4 Guttate psoriasis
0.621 0.379 0.000
L40.3 Pustulosis palmaris et plantaris
0.621 0.379 0.000
L40.2 Acrodermatitis continua
0.621 0.379 0.000
L40.1 Generalised pustular psoriasis
0.621 0.379 0.000
D37.3 Appendix
0.621 0.379 0.000
D37.1 Stomach
0.621 0.379 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.620 0.380 0.000
S70.8 Other superficial injuries of hip and thigh
0.620 0.380 0.000
S70.7 Multiple superficial injuries of hip and thigh
0.620 0.380 0.000
S70.1 Contusion of thigh
0.620 0.380 0.000
S70.0 Contusion of hip
0.620 0.380 0.000
Y54.4 Loop [high-ceiling] diuretics
0.620 0.380 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.619 0.381 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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