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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs113652541
log Bayes Factor = 18.6299
Chromosome 15   position 53,573,692  (GRCh37) Explore rs113652541 on Ensembl!
Variant rs113652541 is part of Cluster X0146

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.999 0.001 0.000
Z51 Other medical care
0.999 0.001 0.000
Z92 Personal history of medical treatment
0.998 0.002 0.000
Chapter VIII Diseases of the ear and mastoid process
0.998 0.002 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.998 0.002 0.000
Z51.2 Other chemotherapy
0.996 0.004 0.000
S60-S69 Injuries to the wrist and hand
0.994 0.006 0.000
H65-H75 Diseases of middle ear and mastoid
0.993 0.007 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.990 0.010 0.000
M70-M79 Other soft tissue disorders
0.987 0.013 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.986 0.014 0.000
I30-I52 Other forms of heart disease
0.986 0.014 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.984 0.016 0.000
Chapter XX External causes of morbidity and mortality
0.980 0.020 0.000
M45-M49 Spondylopathies
0.976 0.024 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.971 0.029 0.000
M65-M68 Disorders of synovium and tendon
0.964 0.036 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.961 0.039 0.000
M05-M14 Inflammatory polyarthropathies
0.960 0.040 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.958 0.042 0.000
M48 Other spondylopathies
0.955 0.045 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.954 0.046 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.952 0.048 0.000
Chapter VII Diseases of the eye and adnexa
0.950 0.050 0.000
I26 Pulmonary embolism
0.947 0.053 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.942 0.058 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.941 0.059 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.940 0.060 0.000
Z92.3 Personal history of irradiation
0.938 0.062 0.000
S62 Fracture at wrist and hand level
0.937 0.063 0.000
M48.0 Spinal stenosis
0.935 0.065 0.000
I49 Other cardiac arrhythmias
0.934 0.066 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.930 0.070 0.000
O60-O75 Complications of labour and delivery
0.922 0.078 0.000
M13 Other arthritis
0.920 0.080 0.000
M80-M85 Disorders of bone density and structure
0.920 0.080 0.000
T81 Complications of procedures, not elsewhere classified
0.915 0.085 0.000
M20-M25 Other joint disorders
0.915 0.085 0.000
Z51.5 Palliative care
0.914 0.086 0.000
Chapter X Diseases of the respiratory system
0.912 0.088 0.000
Y83.8 Other surgical procedures
0.910 0.090 0.000
I60-I69 Cerebrovascular diseases
0.910 0.090 0.000
H71 Cholesteatoma of middle ear
0.909 0.091 0.000
Z98 Other postsurgical states
0.909 0.091 0.000
Z94 Transplanted organ and tissue status
0.909 0.091 0.000
Chapter XIV Diseases of the genitourinary system
0.907 0.093 0.000
Z51.3 Blood transfusion without reported diagnosis
0.907 0.093 0.000
S20-S29 Injuries to the thorax
0.903 0.097 0.000
Z51.0 Radiotherapy session
0.902 0.098 0.000
M48.06 Spinal stenosis (Lumbar region)
0.902 0.098 0.000
H66 Suppurative and unspecified otitis media
0.895 0.105 0.000
Z99.2 Dependence on renal dialysis
0.895 0.105 0.000
M79.6 Pain in limb
0.893 0.107 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.892 0.108 0.000
Z45 Adjustment and management of implanted device
0.889 0.111 0.000
Y83.4 Other reconstructive surgery
0.887 0.113 0.000
M13.9 Arthritis, unspecified
0.884 0.116 0.000
M67 Other disorders of synovium and tendon
0.884 0.116 0.000
I35 Nonrheumatic aortic valve disorders
0.883 0.117 0.000
S62.3 Fracture of other metacarpal bone
0.881 0.119 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.881 0.119 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.879 0.121 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.879 0.121 0.000
M65 Synovitis and tenosynovitis
0.877 0.123 0.000
M75 Shoulder lesions
0.873 0.127 0.000
N30-N39 Other diseases of urinary system
0.871 0.129 0.000
M50-M54 Other dorsopathies
0.867 0.133 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.865 0.135 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.860 0.140 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.860 0.140 0.000
Z48 Other surgical follow-up care
0.857 0.143 0.000
S70-S79 Injuries to the hip and thigh
0.856 0.144 0.000
H74 Other disorders of middle ear and mastoid
0.856 0.144 0.000
Z43 Attention to artificial openings
0.855 0.145 0.000
H72 Perforation of tympanic membrane
0.854 0.146 0.000
Z99.8 Dependence on other enabling machines and devices
0.851 0.149 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.851 0.149 0.000
M86-M90 Other osteopathies
0.850 0.150 0.000
M79.8 Other specified soft tissue disorders
0.849 0.151 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.848 0.152 0.000
I44 Atrioventricular and left bundle-branch block
0.847 0.153 0.000
J90-J94 Other diseases of pleura
0.846 0.154 0.000
Z49 Care involving dialysis
0.844 0.156 0.000
S62.30 Fracture of other metacarpal bone (closed)
0.841 0.159 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.840 0.160 0.000
E70-E90 Metabolic disorders
0.838 0.162 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.837 0.163 0.000
I47 Paroxysmal tachycardia
0.836 0.164 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.836 0.164 0.000
H80-H83 Diseases of inner ear
0.836 0.164 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.834 0.166 0.000
M81 Osteoporosis without pathological fracture
0.832 0.168 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.832 0.168 0.000
I67 Other cerebrovascular diseases
0.829 0.171 0.000
O00-O08 Pregnancy with abortive outcome
0.828 0.172 0.000
Y83.6 Removal of other organ (partial) (total)
0.828 0.172 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.826 0.174 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.823 0.177 0.000
O36 Maternal care for other known or suspected foetal problems
0.822 0.178 0.000
Z94.0 Kidney transplant status
0.821 0.179 0.000
J90 Pleural effusion, not elsewhere classified
0.820 0.180 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.820 0.180 0.000
I45 Other conduction disorders
0.820 0.180 0.000
H30-H36 Disorders of choroid and retina
0.820 0.180 0.000
I49.0 Ventricular fibrillation and flutter
0.817 0.183 0.000
I87 Other disorders of veins
0.816 0.184 0.000
H55-H59 Other disorders of eye and adnexa
0.816 0.184 0.000
N00-N08 Glomerular diseases
0.814 0.186 0.000
I84 Haemorrhoids
0.812 0.188 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.811 0.189 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.810 0.190 0.000
Z52 Donors of organs and tissues
0.810 0.190 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.808 0.192 0.000
H73 Other disorders of tympanic membrane
0.807 0.193 0.000
H50 Other strabismus
0.807 0.193 0.000
I80 Phlebitis and thrombophlebitis
0.807 0.193 0.000
M20 Acquired deformities of fingers and toes
0.807 0.193 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.806 0.194 0.000
I63 Cerebral infarction
0.805 0.195 0.000
H60-H62 Diseases of external ear
0.805 0.195 0.000
Z45.2 Adjustment and management of vascular access device
0.803 0.197 0.000
I35.0 Aortic (valve) stenosis
0.802 0.198 0.000
Z98.8 Other specified postsurgical states
0.797 0.203 0.000
M65.3 Trigger finger
0.797 0.203 0.000
T86 Failure and rejection of transplanted organs and tissues
0.796 0.204 0.000
M91-M94 Chondropathies
0.796 0.204 0.000
S67 Crushing injury of wrist and hand
0.794 0.206 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.794 0.206 0.000
S00-S09 Injuries to the head
0.794 0.206 0.000
M24 Other specific joint derangements
0.793 0.207 0.000
S61 Open wound of wrist and hand
0.792 0.208 0.000
M79.2 Neuralgia and neuritis, unspecified
0.792 0.208 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.792 0.208 0.000
H90-H95 Other disorders of ear
0.790 0.210 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.789 0.211 0.000
I49.9 Cardiac arrhythmia, unspecified
0.789 0.211 0.000
I49.3 Ventricular premature depolarisation
0.787 0.213 0.000
M46 Other inflammatory spondylopathies
0.786 0.214 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.783 0.217 0.000
Z98.0 Intestinal bypass and anastomosis status
0.783 0.217 0.000
J09-J18 Influenza and pneumonia
0.782 0.217 0.000
M15-M19 Arthrosis
0.781 0.219 0.000
O04 Medical abortion
0.780 0.220 0.000
O71 Other obstetric trauma
0.780 0.220 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.780 0.220 0.000
O63 Long labour
0.779 0.221 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.778 0.222 0.000
Z93 Artificial opening status
0.777 0.223 0.000
Chapter XXII Codes for special purposes
0.776 0.224 0.000
I84.1 Internal haemorrhoids with other complications
0.776 0.224 0.000
S40-S49 Injuries to the shoulder and upper arm
0.776 0.224 0.000
H65 Nonsuppurative otitis media
0.775 0.225 0.000
E87.5 Hyperkalaemia
0.773 0.227 0.000
O40 Polyhydramnios
0.772 0.228 0.000
O66 Other obstructed labour
0.772 0.228 0.000
S20 Superficial injury of thorax
0.772 0.228 0.000
E83 Disorders of mineral metabolism
0.771 0.229 0.000
S60 Superficial injury of wrist and hand
0.771 0.229 0.000
M67.8 Other specified disorders of synovium and tendon
0.770 0.229 0.000
I47.2 Ventricular tachycardia
0.770 0.230 0.000
M81.9 Osteoporosis, unspecified
0.769 0.231 0.000
H66.3 Other chronic suppurative otitis media
0.769 0.231 0.000
V10-V19 Pedal cyclist injured in transport accident
0.769 0.231 0.000
S64 Injury of nerves at wrist and hand level
0.768 0.232 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.767 0.233 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.767 0.233 0.000
M79.60 Pain in limb (Multiple sites)
0.766 0.234 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.766 0.234 0.000
O85-O92 Complications predominantly related to the puerperium
0.764 0.236 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.763 0.237 0.000
M79.62 Pain in limb (Upper arm)
0.763 0.237 0.000
N17-N19 Renal failure
0.763 0.237 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.763 0.237 0.000
I86 Varicose veins of other sites
0.763 0.237 0.000
H83 Other diseases of inner ear
0.762 0.238 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.761 0.238 0.000
I34 Nonrheumatic mitral valve disorders
0.759 0.241 0.000
J00-J06 Acute upper respiratory infections
0.758 0.242 0.000
M67.1 Other contracture of tendon (sheath)
0.757 0.243 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.757 0.243 0.000
M22 Disorders of patella
0.757 0.243 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.757 0.243 0.000
H35 Other retinal disorders
0.756 0.244 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.755 0.245 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.755 0.245 0.000
H66.9 Otitis media, unspecified
0.754 0.246 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.753 0.247 0.000
N30 Cystitis
0.752 0.248 0.000
H50.1 Divergent concomitant strabismus
0.751 0.249 0.000
I44.0 Atrioventricular block, first degree
0.751 0.249 0.000
Z92.0 Personal history of contraception
0.748 0.252 0.000
N10-N16 Renal tubulo-interstitial diseases
0.748 0.252 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.747 0.253 0.000
J20-J22 Other acute lower respiratory infections
0.747 0.253 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.745 0.255 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.745 0.255 0.000
O04.9 Complete or unspecified, without complication
0.745 0.255 0.000
I82 Other venous embolism and thrombosis
0.744 0.256 0.000
M10 Gout
0.743 0.257 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.742 0.257 0.000
I49.4 Other and unspecified premature depolarisation
0.742 0.258 0.000
M05 Seropositive rheumatoid arthritis
0.741 0.259 0.000
E83.5 Disorders of calcium metabolism
0.741 0.259 0.000
E87.7 Fluid overload
0.741 0.259 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.741 0.259 0.000
M65.34 Trigger finger-Hand
0.740 0.260 0.000
Z96 Presence of other functional implants
0.740 0.260 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.740 0.260 0.000
M35 Other systemic involvement of connective tissue
0.739 0.261 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.739 0.261 0.000
W00-W19 Falls
0.739 0.261 0.000
Chapter I Certain infectious and parasitic diseases
0.738 0.262 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.738 0.262 0.000
S90-S99 Injuries to the ankle and foot
0.737 0.263 0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.737 0.263 0.000
I27 Other pulmonary heart diseases
0.735 0.265 0.000
M13.98 Arthritis, unspecified (Other)
0.733 0.267 0.000
Z99.1 Dependence on respirator
0.732 0.267 0.000
W20-W49 Exposure to inanimate mechanical forces
0.732 0.267 0.000
M75.1 Rotator cuff syndrome
0.731 0.269 0.000
M79.67 Pain in limb (Ankle and foot)
0.731 0.269 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.730 0.269 0.000
M40-M43 Deforming dorsopathies
0.730 0.270 0.000
T81.9 Unspecified complication of procedure
0.730 0.270 0.000
Z33 Pregnant state, incidental
0.729 0.271 0.000
O43 Placental disorders
0.727 0.273 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.726 0.274 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.726 0.274 0.000
Z94.8 Other transplanted organ and tissue status
0.725 0.275 0.000
M47 Spondylosis
0.725 0.275 0.000
N39 Other disorders of urinary system
0.724 0.276 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.722 0.278 0.000
I42 Cardiomyopathy
0.721 0.279 0.000
M20.1 Hallux valgus (acquired)
0.721 0.279 0.000
S62.6 Fracture of other finger
0.720 0.279 0.000
S71 Open wound of hip and thigh
0.720 0.280 0.000
Z48.8 Other specified surgical follow-up care
0.720 0.280 0.000
S27 Injury of other and unspecified intrathoracic organs
0.720 0.280 0.000
I44.2 Atrioventricular block, complete
0.719 0.281 0.000
M77 Other enthesopathies
0.718 0.282 0.000
Z43.3 Attention to colostomy
0.718 0.282 0.000
M79.5 Residual foreign body in soft tissue
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I51 Complications and ill-defined descriptions of heart disease
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
S69 Other and unspecified injuries of wrist and hand
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Z54 Convalescence
0.716 0.283 0.000
Z44 Fitting and adjustment of external prosthetic device
0.716 0.283 0.000
Z51.9 Medical care, unspecified
0.716 0.284 0.000
Z51.6 Desensitisation to allergens
0.716 0.284 0.000
I67.8 Other specified cerebrovascular diseases
0.716 0.284 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.716 0.284 0.000
Z92.9 Personal history of medical treatment, unspecified
0.716 0.284 0.000
Z92.8 Personal history of other medical treatment
0.716 0.284 0.000
Z92.5 Personal history of rehabilitation measures
0.716 0.284 0.000
M54 Dorsalgia
0.716 0.284 0.000
M80 Osteoporosis with pathological fracture
0.715 0.285 0.000
Z89 Acquired absence of limb
0.715 0.285 0.000
Z84 Family history of other conditions
0.715 0.285 0.000
Z81 Family history of mental and behavioural disorders
0.715 0.285 0.000
Z41 Procedures for purposes other than remedying health state
0.715 0.285 0.000
M51 Other intervertebral disk disorders
0.715 0.285 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.715 0.285 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.714 0.286 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.713 0.287 0.000
N18 Chronic renal failure
0.713 0.287 0.000
S65 Injury of blood vessels at wrist and hand level
0.712 0.287 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.712 0.288 0.000
H70 Mastoiditis and related conditions
0.712 0.288 0.000
H69 Other disorders of Eustachian tube
0.712 0.288 0.000
H68 Eustachian salpingitis and obstruction
0.712 0.288 0.000
H67 Otitis media in diseases classified elsewhere
0.712 0.288 0.000
M13.0 Polyarthritis, unspecified
0.712 0.288 0.000
H35.3 Degeneration of macula and posterior pole
0.711 0.289 0.000
H83.0 Labyrinthitis
0.709 0.291 0.000
H10-H13 Disorders of conjunctiva
0.708 0.292 0.000
S68 Traumatic amputation of wrist and hand
0.708 0.292 0.000
M76 Enthesopathies of lower limb, excluding foot
0.708 0.292 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.708 0.292 0.000
I52 Other heart disorders in diseases classified elsewhere
0.707 0.293 0.000
I48 Atrial fibrillation and flutter
0.707 0.293 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.707 0.293 0.000
I41 Myocarditis in diseases classified elsewhere
0.707 0.293 0.000
I40 Acute myocarditis
0.707 0.293 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.707 0.293 0.000
I37 Pulmonary valve disorders
0.707 0.293 0.000
I36 Nonrheumatic tricuspid valve disorders
0.707 0.293 0.000
I33 Acute and subacute endocarditis
0.707 0.293 0.000
I32 Pericarditis in diseases classified elsewhere
0.707 0.293 0.000
I30 Acute pericarditis
0.707 0.293 0.000
T87 Complications peculiar to reattachment and amputation
0.705 0.295 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.705 0.295 0.000
H52 Disorders of refraction and accommodation
0.705 0.295 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.705 0.295 0.000
O36.6 Maternal care for excessive foetal growth
0.705 0.295 0.000
H74.3 Other acquired abnormalities of ear ossicles
0.704 0.296 0.000
N34 Urethritis and urethral syndrome
0.704 0.296 0.000
Z35 Supervision of high-risk pregnancy
0.703 0.297 0.000
M13.93 Arthritis, unspecified (Forearm)
0.703 0.297 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.703 0.297 0.000
Y35-Y36 Legal intervention and operations of war
0.703 0.297 0.000
Y10-Y34 Event of undetermined intent
0.703 0.297 0.000
Y00-Y09 Assault
0.703 0.297 0.000
X85-X99 Assault
0.703 0.297 0.000
X60-X84 Intentional self-harm
0.703 0.297 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.703 0.297 0.000
X50-X57 Overexertion, travel and privation
0.703 0.297 0.000
X30-X39 Exposure to forces of nature
0.703 0.297 0.000
X20-X29 Contact with venomous animals and plants
0.703 0.297 0.000
X10-X19 Contact with heat and hot substances
0.703 0.297 0.000
X00-X09 Exposure to smoke, fire and flames
0.703 0.297 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.703 0.297 0.000
W75-W84 Other accidental threats to breathing
0.703 0.297 0.000
W65-W74 Accidental drowning and submersion
0.703 0.297 0.000
W50-W64 Exposure to animate mechanical forces
0.703 0.297 0.000
V98-V99 Other and unspecified transport accidents
0.703 0.297 0.000
V95-V97 Air and space transport accidents
0.703 0.297 0.000
V90-V94 Water transport accidents
0.703 0.297 0.000
V80-V89 Other land transport accidents
0.703 0.297 0.000
V70-V79 Bus occupant injured in transport accident
0.703 0.297 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.703 0.297 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.703 0.297 0.000
V40-V49 Car occupant injured in transport accident
0.703 0.297 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.703 0.297 0.000
V01-V09 Pedestrian injured in transport accident
0.703 0.297 0.000
H72.0 Central perforation of tympanic membrane
0.703 0.297 0.000
V20-V29 Motorcycle rider injured in transport accident
0.702 0.298 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.702 0.298 0.000
S62.5 Fracture of thumb
0.702 0.298 0.000
M84 Disorders of continuity of bone
0.701 0.299 0.000
Z71.8 Other specified counselling
0.701 0.299 0.000
M71 Other bursopathies
0.700 0.300 0.000
M49 Spondylopathies in diseases classified elsewhere
0.699 0.300 0.000
M75.4 Impingement syndrome of shoulder
0.699 0.301 0.000
H74.0 Tympanosclerosis
0.699 0.301 0.000
M89 Other disorders of bone
0.699 0.301 0.000
O48 Prolonged pregnancy
0.698 0.302 0.000
M18 Arthrosis of first carpometacarpal joint
0.697 0.303 0.000
H34 Retinal vascular occlusions
0.697 0.303 0.000
I28 Other diseases of pulmonary vessels
0.696 0.304 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.696 0.304 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.693 0.306 0.000
N40-N51 Diseases of male genital organs
0.693 0.307 0.000
O47 False labour
0.693 0.307 0.000
E00-E07 Disorders of thyroid gland
0.692 0.307 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.691 0.309 0.000
M66 Spontaneous rupture of synovium and tendon
0.691 0.309 0.000
O30 Multiple gestation
0.691 0.309 0.000
Y83.0 Surgical operation with transplant of whole organ
0.690 0.309 0.000
Z49.0 Preparatory care for dialysis
0.690 0.310 0.000
D68 Other coagulation defects
0.690 0.310 0.000
M31 Other necrotising vasculopathies
0.690 0.310 0.000
Z99.9 Dependence on unspecified enabling machine and device
0.689 0.311 0.000
Z99.4 Dependence on artificial heart
0.689 0.311 0.000
Z99.0 Dependence on aspirator
0.689 0.311 0.000
T79-T79 Certain early complications of trauma
0.689 0.311 0.000
J02 Acute pharyngitis
0.689 0.311 0.000
N35 Urethral stricture
0.689 0.311 0.000
I87.2 Venous insufficiency (chronic) (peripheral)
0.689 0.311 0.000
M14 Arthropathies in other diseases classified elsewhere
0.688 0.312 0.000
M12 Other specific arthropathies
0.688 0.312 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.688 0.312 0.000
M08 Juvenile arthritis
0.688 0.312 0.000
M75.3 Calcific tendinitis of shoulder
0.688 0.312 0.000
M07 Psoriatic and enteropathic arthropathies
0.687 0.313 0.000
M79.9 Soft tissue disorder, unspecified
0.687 0.313 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.687 0.313 0.000
M79.3 Panniculitis, unspecified
0.687 0.313 0.000
M79.1 Myalgia
0.687 0.313 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.686 0.314 0.000
M48.9 Spondylopathy, unspecified
0.685 0.315 0.000
M48.8 Other specified spondylopathies
0.685 0.315 0.000
M48.4 Fatigue fracture of vertebra
0.685 0.315 0.000
M48.3 Traumatic spondylopathy
0.685 0.315 0.000
M48.2 Kissing spine
0.685 0.315 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.685 0.315 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.684 0.316 0.000
I88 Nonspecific lymphadenitis
0.684 0.316 0.000
I81 Portal vein thrombosis
0.684 0.316 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.682 0.318 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.682 0.318 0.000
Z43.6 Attention to other artificial openings of urinary tract
0.682 0.318 0.000
M72 Fibroblastic disorders
0.681 0.319 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.681 0.319 0.000
Z45.8 Adjustment and management of other implanted devices
0.680 0.320 0.000
Y83.3 Surgical operation with formation of external stoma
0.680 0.320 0.000
Z52.3 Bone marrow donor
0.679 0.321 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.679 0.321 0.000
S01 Open wound of head
0.678 0.322 0.000
M21 Other acquired deformities of limbs
0.678 0.322 0.000
M86 Osteomyelitis
0.678 0.322 0.000
N30.2 Other chronic cystitis
0.678 0.322 0.000
O71.4 Obstetric high vaginal laceration alone
0.678 0.322 0.000
I84.3 External thrombosed haemorrhoids
0.677 0.323 0.000
S61.8 Open wound of other parts of wrist and hand
0.677 0.323 0.000
I67.2 Cerebral atherosclerosis
0.677 0.323 0.000
M11 Other crystal arthropathies
0.676 0.323 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.676 0.324 0.000
M75.5 Bursitis of shoulder
0.676 0.324 0.000
Z76 Persons encountering health services in other circumstances
0.676 0.324 0.000
Q60-Q64 Congenital malformations of the urinary system
0.675 0.324 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.675 0.324 0.000
O45 Premature separation of placenta [abruptio placentae]
0.675 0.325 0.000
O44 Placenta praevia
0.675 0.325 0.000
O41 Other disorders of amniotic fluid and membranes
0.675 0.325 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.675 0.325 0.000
O33 Maternal care for known or suspected disproportion
0.675 0.325 0.000
O31 Complications specific to multiple gestation
0.675 0.325 0.000
Y83.5 Amputation of limb(s)
0.674 0.326 0.000
H73.8 Other specified disorders of tympanic membrane
0.674 0.326 0.000
J18 Pneumonia, organism unspecified
0.674 0.326 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.673 0.326 0.000
M79.28 Neuralgia and neuritis, unspecified (Other)
0.673 0.327 0.000
S62.8 Fracture of other and unspecified parts of wrist and hand
0.672 0.328 0.000
S62.7 Multiple fractures of fingers
0.672 0.328 0.000
S62.4 Multiple fractures of metacarpal bones
0.672 0.328 0.000
S62.2 Fracture of first metacarpal bone
0.672 0.328 0.000
S62.1 Fracture of other carpal bone(s)
0.672 0.328 0.000
S62.0 Fracture of navicular [scaphoid] bone of hand
0.672 0.328 0.000
D80-D89 Certain disorders involving the immune mechanism
0.672 0.328 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.671 0.329 0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)
0.671 0.329 0.000
M48.05 Spinal stenosis (Thoracolumbar region)
0.671 0.329 0.000
M48.04 Spinal stenosis (Thoracic region)
0.671 0.329 0.000
M48.03 Spinal stenosis (Cervicothoracic region)
0.671 0.329 0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)
0.671 0.329 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.671 0.329 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.671 0.329 0.000
N99-N99 Other disorders of the genitourinary system
0.670 0.330 0.000
Z49.1 Extracorporeal dialysis
0.670 0.330 0.000
I44.3 Other and unspecified atrioventricular block
0.670 0.330 0.000
I49.2 Junctional premature depolarisation
0.670 0.330 0.000
I49.1 Atrial premature depolarisation
0.670 0.330 0.000
M06 Other rheumatoid arthritis
0.669 0.331 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.669 0.331 0.000
S20.2 Contusion of thorax
0.669 0.331 0.000
H21 Other disorders of iris and ciliary body
0.668 0.332 0.000
Z43.1 Attention to gastrostomy
0.668 0.332 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.668 0.332 0.000
I35.8 Other aortic valve disorders
0.668 0.332 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.668 0.332 0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified
0.667 0.333 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.667 0.333 0.000
D55-D59 Haemolytic anaemias
0.666 0.334 0.000
I45.3 Trifascicular block
0.665 0.335 0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified
0.665 0.335 0.000
J60-J70 Lung diseases due to external agents
0.664 0.336 0.000
H57 Other disorders of eye and adnexa
0.664 0.336 0.000
H65.3 Chronic mucoid otitis media
0.664 0.336 0.000
M22.4 Chondromalacia patellae
0.663 0.337 0.000
I63.9 Cerebral infarction, unspecified
0.663 0.337 0.000
Z93.6 Other artificial openings of urinary tract status
0.662 0.338 0.000
N36 Other disorders of urethra
0.661 0.339 0.000
T86.1 Kidney transplant failure and rejection
0.661 0.339 0.000
O74 Complications of anaesthesia during labour and delivery
0.661 0.339 0.000
O73 Retained placenta and membranes, without haemorrhage
0.661 0.339 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.661 0.339 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.661 0.339 0.000
O62 Abnormalities of forces of labour
0.661 0.339 0.000
O61 Failed induction of labour
0.661 0.339 0.000
O60 Preterm delivery
0.661 0.339 0.000
O75.7 Vaginal delivery following previous Caesarean section
0.660 0.339 0.000
S32 Fracture of lumbar spine and pelvis
0.660 0.340 0.000
N04 Nephrotic syndrome
0.660 0.340 0.000
I62 Other nontraumatic intracranial haemorrhage
0.660 0.340 0.000
S02 Fracture of skull and facial bones
0.660 0.340 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.660 0.340 0.000
M13.8 Other specified arthritis
0.659 0.340 0.000
M13.1 Monoarthritis, not elsewhere classified
0.659 0.340 0.000
M85 Other disorders of bone density and structure
0.659 0.341 0.000
M83 Adult osteomalacia
0.659 0.341 0.000
M82 Osteoporosis in diseases classified elsewhere
0.659 0.341 0.000
Z48.9 Surgical follow-up care, unspecified
0.659 0.341 0.000
Z86 Personal history of certain other diseases
0.658 0.342 0.000
Z46 Fitting and adjustment of other devices
0.658 0.342 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.657 0.343 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.656 0.344 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.656 0.344 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.656 0.344 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.656 0.344 0.000
M34 Systemic sclerosis
0.656 0.344 0.000
M33 Dermatopolymyositis
0.656 0.344 0.000
M32 Systemic lupus erythematosus
0.656 0.344 0.000
M30 Polyarteritis nodosa and related conditions
0.656 0.344 0.000
M13.94 Arthritis, unspecified (Hand)
0.655 0.345 0.000
M48.09 Spinal stenosis (Site unspecified)
0.653 0.346 0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)
0.653 0.347 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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