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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs113994472
log Bayes Factor = 15.0393
Chromosome 1   position 26,737,645  (GRCh37) Explore rs113994472 on Ensembl!
Variant rs113994472 is part of Cluster X0032

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E70-E90 Metabolic disorders
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E86 Volume depletion
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.997 0.003 0.000
M70-M79 Other soft tissue disorders
0.995 0.005 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.993 0.007 0.000
G40-G47 Episodic and paroxysmal disorders
0.988 0.012 0.000
I42 Cardiomyopathy
0.987 0.013 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.986 0.014 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.985 0.015 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.985 0.015 0.000
M79.6 Pain in limb
0.983 0.017 0.000
E00-E07 Disorders of thyroid gland
0.983 0.017 0.000
M80-M85 Disorders of bone density and structure
0.983 0.017 0.000
S60-S69 Injuries to the wrist and hand
0.979 0.021 0.000
I47 Paroxysmal tachycardia
0.977 0.023 0.000
I44 Atrioventricular and left bundle-branch block
0.977 0.023 0.000
M79.66 Pain in limb (Lower leg)
0.976 0.024 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.971 0.029 0.000
G47 Sleep disorders
0.966 0.034 0.000
M81 Osteoporosis without pathological fracture
0.964 0.036 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.963 0.037 0.000
S62 Fracture at wrist and hand level
0.956 0.044 0.000
I42.0 Dilated cardiomyopathy
0.954 0.046 0.000
M81.9 Osteoporosis, unspecified
0.947 0.053 0.000
M20-M25 Other joint disorders
0.945 0.055 0.000
M79.0 Rheumatism, unspecified
0.942 0.058 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.940 0.060 0.000
G47.3 Sleep apnoea
0.938 0.062 0.000
I44.7 Left bundle-branch block, unspecified
0.935 0.065 0.000
Chapter XX External causes of morbidity and mortality
0.934 0.066 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.928 0.072 0.000
S62.6 Fracture of other finger
0.926 0.074 0.000
E04 Other non-toxic goitre
0.923 0.077 0.000
E87.7 Fluid overload
0.919 0.081 0.000
E78.5 Hyperlipidaemia, unspecified
0.918 0.082 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.913 0.087 0.000
G43 Migraine
0.912 0.088 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.911 0.089 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.910 0.090 0.000
I42.9 Cardiomyopathy, unspecified
0.907 0.093 0.000
E87.5 Hyperkalaemia
0.906 0.094 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.904 0.096 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.902 0.098 0.000
M40-M43 Deforming dorsopathies
0.901 0.099 0.000
M79.69 Pain in limb (Site unspecified)
0.893 0.107 0.000
I47.2 Ventricular tachycardia
0.890 0.110 0.000
S70-S79 Injuries to the hip and thigh
0.883 0.117 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.883 0.117 0.000
E03 Other hypothyroidism
0.882 0.118 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.880 0.120 0.000
T87 Complications peculiar to reattachment and amputation
0.879 0.121 0.000
G20-G26 Extrapyramidal and movement disorders
0.878 0.122 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.875 0.125 0.000
Chapter VIII Diseases of the ear and mastoid process
0.873 0.127 0.000
R41.0 Disorientation, unspecified
0.868 0.132 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.868 0.132 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.868 0.132 0.000
I81 Portal vein thrombosis
0.867 0.133 0.000
M50-M54 Other dorsopathies
0.866 0.134 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.866 0.134 0.000
M86-M90 Other osteopathies
0.865 0.135 0.000
I50 Heart failure
0.864 0.136 0.000
E04.1 Non-toxic single thyroid nodule
0.862 0.138 0.000
I89.0 Lymphoedema, not elsewhere classified
0.862 0.138 0.000
T81 Complications of procedures, not elsewhere classified
0.861 0.139 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.861 0.139 0.000
S62.60 Fracture of other finger (closed)
0.860 0.140 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.855 0.145 0.000
M91-M94 Chondropathies
0.855 0.145 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.854 0.146 0.000
I49 Other cardiac arrhythmias
0.854 0.146 0.000
M24 Other specific joint derangements
0.853 0.147 0.000
Chapter V Mental and behavioural disorders
0.851 0.149 0.000
H90-H95 Other disorders of ear
0.850 0.150 0.000
E85 Amyloidosis
0.846 0.153 0.000
M34 Systemic sclerosis
0.845 0.155 0.000
S90-S99 Injuries to the ankle and foot
0.845 0.155 0.000
E06 Thyroiditis
0.844 0.156 0.000
G90-G99 Other disorders of the nervous system
0.842 0.158 0.000
I84 Haemorrhoids
0.840 0.160 0.000
G43.9 Migraine, unspecified
0.839 0.161 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.839 0.161 0.000
S62.61 Fracture of other finger (open)
0.838 0.162 0.000
I47.1 Supraventricular tachycardia
0.838 0.162 0.000
M79.64 Pain in limb (Hand)
0.836 0.164 0.000
G44 Other headache syndromes
0.836 0.164 0.000
H91 Other hearing loss
0.830 0.170 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.829 0.171 0.000
I10-I15 Hypertensive diseases
0.821 0.179 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.819 0.181 0.000
M54 Dorsalgia
0.818 0.182 0.000
G20 Parkinson's disease
0.817 0.183 0.000
H91.9 Hearing loss, unspecified
0.815 0.185 0.000
I84.6 Residual haemorrhoidal skin tags
0.813 0.187 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.813 0.187 0.000
E03.9 Hypothyroidism, unspecified
0.809 0.191 0.000
R45 Symptoms and signs involving emotional state
0.809 0.191 0.000
I85 Oesophageal varices
0.809 0.191 0.000
G47.9 Sleep disorder, unspecified
0.807 0.193 0.000
T86 Failure and rejection of transplanted organs and tissues
0.806 0.194 0.000
G70-G73 Diseases of myoneural junction and muscle
0.806 0.194 0.000
M21 Other acquired deformities of limbs
0.803 0.197 0.000
I49.3 Ventricular premature depolarisation
0.802 0.198 0.000
M23 Internal derangement of knee
0.801 0.199 0.000
S61 Open wound of wrist and hand
0.801 0.199 0.000
Chapter XIV Diseases of the genitourinary system
0.800 0.200 0.000
I82 Other venous embolism and thrombosis
0.800 0.200 0.000
I42.2 Other hypertrophic cardiomyopathy
0.797 0.203 0.000
S70 Superficial injury of hip and thigh
0.796 0.204 0.000
M15-M19 Arthrosis
0.796 0.204 0.000
I31 Other diseases of pericardium
0.795 0.205 0.000
E40-E46 Malnutrition
0.795 0.205 0.000
R50-R69 General symptoms and signs
0.792 0.208 0.000
I38 Endocarditis, valve unspecified
0.792 0.208 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.791 0.209 0.000
M89 Other disorders of bone
0.790 0.210 0.000
I12 Hypertensive renal disease
0.789 0.211 0.000
E10-E14 Diabetes mellitus
0.788 0.212 0.000
G30-G32 Other degenerative diseases of the nervous system
0.786 0.214 0.000
E65-E68 Obesity and other hyperalimentation
0.783 0.217 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.782 0.218 0.000
E20-E35 Disorders of other endocrine glands
0.782 0.218 0.000
E87.3 Alkalosis
0.782 0.218 0.000
E78.8 Other disorders of lipoprotein metabolism
0.782 0.218 0.000
E78.4 Other hyperlipidaemia
0.781 0.219 0.000
M41 Scoliosis
0.781 0.219 0.000
M79.7 Fibromyalgia
0.780 0.220 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.779 0.221 0.000
I44.2 Atrioventricular block, complete
0.778 0.222 0.000
S62.5 Fracture of thumb
0.778 0.222 0.000
M54.5 Low back pain
0.778 0.222 0.000
I44.0 Atrioventricular block, first degree
0.778 0.222 0.000
T87.6 Other and unspecified complications of amputation stump
0.777 0.223 0.000
W00-W19 Falls
0.775 0.225 0.000
N17-N19 Renal failure
0.775 0.225 0.000
I88 Nonspecific lymphadenitis
0.774 0.226 0.000
R27 Other lack of coordination
0.772 0.228 0.000
M79.8 Other specified soft tissue disorders
0.772 0.228 0.000
M80 Osteoporosis with pathological fracture
0.772 0.228 0.000
Y52 Agents primarily affecting the cardiovascular system
0.771 0.229 0.000
S60 Superficial injury of wrist and hand
0.771 0.229 0.000
M79.63 Pain in limb (Forearm)
0.770 0.230 0.000
M79.1 Myalgia
0.770 0.230 0.000
Y44 Agents primarily affecting blood constituents
0.769 0.231 0.000
G47.8 Other sleep disorders
0.768 0.232 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.767 0.233 0.000
S69 Other and unspecified injuries of wrist and hand
0.766 0.234 0.000
I12.0 Hypertensive renal disease with renal failure
0.765 0.235 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.763 0.237 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.763 0.237 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.760 0.240 0.000
N17 Acute renal failure
0.759 0.241 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.759 0.241 0.000
M54.56 Low back pain (Lumbar region)
0.759 0.241 0.000
V98-V99 Other and unspecified transport accidents
0.758 0.242 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.755 0.245 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.755 0.245 0.000
M60-M63 Disorders of muscles
0.755 0.245 0.000
R25 Abnormal involuntary movements
0.754 0.246 0.000
I05-I09 Chronic rheumatic heart diseases
0.754 0.246 0.000
T92 Sequelae of injuries of upper limb
0.754 0.246 0.000
I44.6 Other and unspecified fascicular block
0.753 0.247 0.000
M81.2 Osteoporosis of disuse
0.752 0.248 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.750 0.250 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.749 0.251 0.000
E78.1 Pure hyperglyceridaemia
0.748 0.251 0.000
M82 Osteoporosis in diseases classified elsewhere
0.748 0.252 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.748 0.252 0.000
N17.9 Acute renal failure, unspecified
0.747 0.253 0.000
R59 Enlarged lymph nodes
0.746 0.254 0.000
M77 Other enthesopathies
0.745 0.255 0.000
E06.3 Autoimmune thyroiditis
0.744 0.256 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.740 0.260 0.000
I80 Phlebitis and thrombophlebitis
0.738 0.262 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.738 0.262 0.000
M34.1 CR(E)ST syndrome
0.738 0.262 0.000
M71 Other bursopathies
0.736 0.264 0.000
M19 Other arthrosis
0.736 0.264 0.000
M72 Fibroblastic disorders
0.736 0.264 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.736 0.264 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.736 0.264 0.000
M84 Disorders of continuity of bone
0.735 0.265 0.000
S62.3 Fracture of other metacarpal bone
0.735 0.265 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.734 0.266 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.731 0.269 0.000
R59.0 Localised enlarged lymph nodes
0.731 0.269 0.000
Y43 Primarily systemic agents
0.730 0.270 0.000
G90 Disorders of autonomic nervous system
0.730 0.270 0.000
G37 Other demyelinating diseases of central nervous system
0.730 0.270 0.000
I50.0 Congestive heart failure
0.730 0.270 0.000
S67 Crushing injury of wrist and hand
0.730 0.270 0.000
N25-N29 Other disorders of kidney and ureter
0.730 0.270 0.000
M92 Other juvenile osteochondrosis
0.729 0.271 0.000
I84.3 External thrombosed haemorrhoids
0.728 0.272 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.727 0.273 0.000
Q50-Q56 Congenital malformations of genital organs
0.726 0.274 0.000
R45.1 Restlessness and agitation
0.726 0.274 0.000
S61.1 Open wound of finger(s) with damage to nail
0.726 0.274 0.000
S90 Superficial injury of ankle and foot
0.726 0.274 0.000
G44.0 Cluster headache syndrome
0.726 0.274 0.000
E04.2 Non-toxic multinodular goitre
0.725 0.275 0.000
E80.4 Gilbert's syndrome
0.724 0.276 0.000
M43 Other deforming dorsopathies
0.724 0.276 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.723 0.277 0.000
M31 Other necrotising vasculopathies
0.722 0.278 0.000
I84.7 Unspecified thrombosed haemorrhoids
0.722 0.278 0.000
I44.1 Atrioventricular block, second degree
0.721 0.279 0.000
I84.8 Unspecified haemorrhoids with other complications
0.719 0.281 0.000
M21.2 Flexion deformity
0.718 0.282 0.000
E84 Cystic fibrosis
0.717 0.283 0.000
E79 Disorders of purine and pyrimidine metabolism
0.717 0.283 0.000
E77 Disorders of glycoprotein metabolism
0.717 0.283 0.000
E76 Disorders of glycosaminoglycan metabolism
0.717 0.283 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.717 0.283 0.000
E74 Other disorders of carbohydrate metabolism
0.717 0.283 0.000
E72 Other disorders of amino-acid metabolism
0.717 0.283 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.717 0.283 0.000
E70 Disorders of aromatic amino-acid metabolism
0.717 0.283 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
N00-N08 Glomerular diseases
0.717 0.283 0.000
I30 Acute pericarditis
0.716 0.284 0.000
S62.4 Multiple fractures of metacarpal bones
0.716 0.284 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.716 0.284 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.715 0.285 0.000
T33-T35 Frostbite
0.714 0.285 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.714 0.285 0.000
T00-T07 Injuries involving multiple body regions
0.714 0.285 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.713 0.286 0.000
I34 Nonrheumatic mitral valve disorders
0.713 0.287 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.713 0.287 0.000
M79.9 Soft tissue disorder, unspecified
0.712 0.288 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.712 0.288 0.000
M79.3 Panniculitis, unspecified
0.712 0.288 0.000
M79.2 Neuralgia and neuritis, unspecified
0.712 0.288 0.000
M54.9 Dorsalgia, unspecified
0.712 0.288 0.000
M76 Enthesopathies of lower limb, excluding foot
0.711 0.289 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.710 0.290 0.000
V40-V49 Car occupant injured in transport accident
0.710 0.290 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.708 0.292 0.000
G41 Status epilepticus
0.708 0.292 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.707 0.292 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.708 0.292 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.707 0.292 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.707 0.293 0.000
I42.6 Alcoholic cardiomyopathy
0.707 0.293 0.000
I42.5 Other restrictive cardiomyopathy
0.707 0.293 0.000
I42.4 Endocardial fibroelastosis
0.707 0.293 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.707 0.293 0.000
S62.8 Fracture of other and unspecified parts of wrist and hand
0.707 0.293 0.000
E87.4 Mixed disorder of acid-base balance
0.706 0.294 0.000
M24.2 Disorder of ligament
0.705 0.294 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.705 0.295 0.000
M79.68 Pain in limb (Other)
0.705 0.295 0.000
M79.61 Pain in limb (Shoulder region)
0.705 0.295 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.705 0.295 0.000
E00 Congenital iodine-deficiency syndrome
0.705 0.295 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.705 0.295 0.000
M83 Adult osteomalacia
0.705 0.295 0.000
I86 Varicose veins of other sites
0.703 0.297 0.000
E88 Other metabolic disorders
0.703 0.297 0.000
S70.9 Superficial injury of hip and thigh, unspecified
0.703 0.297 0.000
S65 Injury of blood vessels at wrist and hand level
0.702 0.298 0.000
G35 Multiple sclerosis
0.702 0.298 0.000
X20-X29 Contact with venomous animals and plants
0.701 0.298 0.000
I47.0 Reentry ventricular arrhythmia
0.700 0.299 0.000
I44.5 Left posterior fascicular block
0.700 0.300 0.000
I44.4 Left anterior fascicular block
0.700 0.300 0.000
I31.3 Pericardial effusion (noninflammatory)
0.700 0.300 0.000
E85.9 Amyloidosis, unspecified
0.699 0.301 0.000
E78.6 Lipoprotein deficiency
0.696 0.304 0.000
E78.3 Hyperchylomicronaemia
0.696 0.304 0.000
F41 Other anxiety disorders
0.696 0.304 0.000
M41.9 Scoliosis, unspecified
0.694 0.306 0.000
I44.3 Other and unspecified atrioventricular block
0.694 0.306 0.000
T87.4 Infection of amputation stump
0.693 0.306 0.000
G47.4 Narcolepsy and cataplexy
0.693 0.307 0.000
G47.2 Disorders of the sleep-wake schedule
0.693 0.307 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.693 0.307 0.000
M81.8 Other osteoporosis
0.691 0.309 0.000
M81.6 Localised osteoporosis [Lequesne]
0.691 0.309 0.000
M81.5 Idiopathic osteoporosis
0.691 0.309 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.691 0.309 0.000
M81.1 Postoophorectomy osteoporosis
0.691 0.309 0.000
M81.0 Postmenopausal osteoporosis
0.691 0.309 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.691 0.309 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.691 0.309 0.000
G43.8 Other migraine
0.690 0.310 0.000
Y44.2 Anticoagulants
0.690 0.310 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.688 0.312 0.000
E78.0 Pure hypercholesterolaemia
0.688 0.312 0.000
S61.8 Open wound of other parts of wrist and hand
0.688 0.312 0.000
E73 Lactose intolerance
0.688 0.312 0.000
I87 Other disorders of veins
0.688 0.312 0.000
M00-M03 Infectious arthropathies
0.688 0.312 0.000
I85.9 Oesophageal varices without bleeding
0.687 0.313 0.000
E78.2 Mixed hyperlipidaemia
0.687 0.313 0.000
G43.1 Migraine with aura [classical migraine]
0.687 0.313 0.000
I50.1 Left ventricular failure
0.686 0.314 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.686 0.314 0.000
M34.9 Systemic sclerosis, unspecified
0.686 0.314 0.000
S62.7 Multiple fractures of fingers
0.685 0.314 0.000
S62.1 Fracture of other carpal bone(s)
0.685 0.314 0.000
S62.0 Fracture of navicular [scaphoid] bone of hand
0.685 0.314 0.000
M23.0 Cystic meniscus
0.685 0.315 0.000
M40 Kyphosis and lordosis
0.685 0.315 0.000
M81.4 Drug-induced osteoporosis
0.683 0.317 0.000
X60-X84 Intentional self-harm
0.682 0.318 0.000
M19.9 Arthrosis, unspecified
0.681 0.319 0.000
R27.8 Other and unspecified lack of coordination
0.681 0.319 0.000
E04.9 Non-toxic goitre, unspecified
0.680 0.319 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.680 0.320 0.000
T79-T79 Certain early complications of trauma
0.680 0.320 0.000
S99 Other and unspecified injuries of ankle and foot
0.679 0.321 0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)
0.679 0.321 0.000
M81.96 Osteoporosis, unspecified (Lower leg)
0.679 0.321 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.679 0.321 0.000
M81.94 Osteoporosis, unspecified (Hand)
0.679 0.321 0.000
M81.93 Osteoporosis, unspecified (Forearm)
0.679 0.321 0.000
M81.92 Osteoporosis, unspecified (Upper arm)
0.679 0.321 0.000
M81.91 Osteoporosis, unspecified (Shoulder region)
0.679 0.321 0.000
W19 Unspecified fall
0.678 0.322 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.678 0.322 0.000
M33 Dermatopolymyositis
0.678 0.322 0.000
M32 Systemic lupus erythematosus
0.678 0.322 0.000
M30 Polyarteritis nodosa and related conditions
0.678 0.322 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.677 0.322 0.000
W20-W49 Exposure to inanimate mechanical forces
0.677 0.323 0.000
S64 Injury of nerves at wrist and hand level
0.677 0.323 0.000
M79.08 Rheumatism, unspecified (Other)
0.675 0.325 0.000
M79.07 Rheumatism, unspecified (Ankle and foot)
0.675 0.325 0.000
M79.06 Rheumatism, unspecified (Lower leg)
0.675 0.325 0.000
M79.05 Rheumatism, unspecified (Pelvic region and thigh)
0.675 0.325 0.000
M79.04 Rheumatism, unspecified (Hand)
0.675 0.325 0.000
M79.03 Rheumatism, unspecified (Forearm)
0.675 0.325 0.000
M79.02 Rheumatism, unspecified (Upper arm)
0.675 0.325 0.000
M79.01 Rheumatism, unspecified (Shoulder region)
0.675 0.325 0.000
M24.1 Other articular cartilage disorders
0.675 0.325 0.000
R60 Oedema, not elsewhere classified
0.674 0.326 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.674 0.326 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.673 0.327 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.673 0.327 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.673 0.327 0.000
W50-W64 Exposure to animate mechanical forces
0.672 0.327 0.000
T86.8 Failure and rejection of other transplanted organs and tissues
0.672 0.328 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.672 0.328 0.000
M85 Other disorders of bone density and structure
0.671 0.328 0.000
Y48 Anaesthetics and therapeutic gases
0.670 0.330 0.000
T92.1 Sequelae of fracture of arm
0.670 0.330 0.000
Y35-Y36 Legal intervention and operations of war
0.670 0.330 0.000
Y10-Y34 Event of undetermined intent
0.670 0.330 0.000
Y00-Y09 Assault
0.670 0.330 0.000
X85-X99 Assault
0.670 0.330 0.000
X50-X57 Overexertion, travel and privation
0.670 0.330 0.000
X30-X39 Exposure to forces of nature
0.670 0.330 0.000
X10-X19 Contact with heat and hot substances
0.670 0.330 0.000
X00-X09 Exposure to smoke, fire and flames
0.670 0.330 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.670 0.330 0.000
W75-W84 Other accidental threats to breathing
0.670 0.330 0.000
W65-W74 Accidental drowning and submersion
0.670 0.330 0.000
V95-V97 Air and space transport accidents
0.670 0.330 0.000
V90-V94 Water transport accidents
0.670 0.330 0.000
V70-V79 Bus occupant injured in transport accident
0.670 0.330 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.670 0.330 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.670 0.330 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.670 0.330 0.000
V01-V09 Pedestrian injured in transport accident
0.670 0.330 0.000
S60.8 Other superficial injuries of wrist and hand
0.670 0.330 0.000
M79.89 Other specified soft tissue disorders (Site unspecified)
0.670 0.330 0.000
E11 Non-insulin-dependent diabetes mellitus
0.670 0.330 0.000
E85.4 Organ-limited amyloidosis
0.668 0.332 0.000
E87.0 Hyperosmolality and hypernatraemia
0.667 0.333 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.667 0.333 0.000
H92 Otalgia and effusion of ear
0.667 0.333 0.000
S71 Open wound of hip and thigh
0.667 0.333 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.665 0.335 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.665 0.335 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.663 0.337 0.000
S10-S19 Injuries to the neck
0.663 0.337 0.000
I42.8 Other cardiomyopathies
0.662 0.338 0.000
E04.8 Other specified non-toxic goitre
0.662 0.338 0.000
E04.0 Non-toxic diffuse goitre
0.662 0.338 0.000
T40.2 Other opioids
0.662 0.338 0.000
R42 Dizziness and giddiness
0.662 0.338 0.000
N28.1 Cyst of kidney, acquired
0.660 0.340 0.000
F99-F99 Unspecified mental disorder
0.659 0.341 0.000
T91 Sequelae of injuries of neck and trunk
0.658 0.342 0.000
S79 Other and unspecified injuries of hip and thigh
0.658 0.342 0.000
I51 Complications and ill-defined descriptions of heart disease
0.658 0.342 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.657 0.342 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.657 0.343 0.000
M89.3 Hypertrophy of bone
0.657 0.343 0.000
M94 Other disorders of cartilage
0.657 0.343 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.656 0.343 0.000
I36 Nonrheumatic tricuspid valve disorders
0.656 0.344 0.000
Y57 Other and unspecified drugs and medicaments
0.654 0.346 0.000
G43.3 Complicated migraine
0.654 0.346 0.000
G43.2 Status migrainosus
0.654 0.346 0.000
G43.0 Migraine without aura [common migraine]
0.654 0.346 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.654 0.346 0.000
Q60-Q64 Congenital malformations of the urinary system
0.654 0.346 0.000
M54.50 Low back pain (Multiple sites in spine)
0.653 0.347 0.000
R46 Symptoms and signs involving appearance and behaviour
0.653 0.347 0.000
R43 Disturbances of smell and taste
0.653 0.347 0.000
I82.8 Embolism and thrombosis of other specified veins
0.652 0.347 0.000
E50-E64 Other nutritional deficiencies
0.652 0.348 0.000
R51 Headache
0.652 0.348 0.000
S62.50 Fracture of thumb (closed)
0.651 0.349 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.650 0.350 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.649 0.351 0.000
E27 Other disorders of adrenal gland
0.649 0.351 0.000
G70 Myasthenia gravis and other myoneural disorders
0.649 0.351 0.000
R57 Shock, not elsewhere classified
0.648 0.352 0.000
I49.4 Other and unspecified premature depolarisation
0.648 0.352 0.000
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.648 0.352 0.000
M17 Gonarthrosis [arthrosis of knee]
0.648 0.352 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.648 0.352 0.000
E46 Unspecified protein-energy malnutrition
0.648 0.352 0.000
R54 Senility
0.648 0.352 0.000
M86 Osteomyelitis
0.647 0.353 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.647 0.353 0.000
T85.2 Mechanical complication of intraocular lens
0.647 0.353 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.646 0.353 0.000
M42 Spinal osteochondrosis
0.646 0.354 0.000
T88.5 Other complications of anaesthesia
0.646 0.354 0.000
T17 Foreign body in respiratory tract
0.646 0.354 0.000
S70.0 Contusion of hip
0.646 0.354 0.000
M23.3 Other meniscus derangements
0.645 0.355 0.000
M20 Acquired deformities of fingers and toes
0.645 0.355 0.000
R61 Hyperhidrosis
0.644 0.356 0.000
M79.62 Pain in limb (Upper arm)
0.643 0.357 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.643 0.357 0.000
R41.2 Retrograde amnesia
0.643 0.357 0.000
H60-H62 Diseases of external ear
0.643 0.357 0.000
E13 Other specified diabetes mellitus
0.642 0.358 0.000
I49.9 Cardiac arrhythmia, unspecified
0.642 0.358 0.000
V80-V89 Other land transport accidents
0.641 0.359 0.000
W19.9 Unspecified place
0.640 0.360 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.639 0.361 0.000
M24.0 Loose body in joint
0.637 0.363 0.000
Q80-Q89 Other congenital malformations
0.637 0.363 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.637 0.363 0.000
R21 Rash and other nonspecific skin eruption
0.636 0.364 0.000
R29.6 Tendency to fall, not elsewhere classified
0.636 0.364 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.636 0.364 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.636 0.364 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.635 0.365 0.000
G95 Other diseases of spinal cord
0.635 0.365 0.000
S78 Traumatic amputation of hip and thigh
0.633 0.367 0.000
S77 Crushing injury of hip and thigh
0.633 0.367 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.633 0.367 0.000
S75 Injury of blood vessels at hip and thigh level
0.633 0.367 0.000
S74 Injury of nerves at hip and thigh level
0.633 0.367 0.000
M89.8 Other specified disorders of bone
0.633 0.367 0.000
R41.1 Anterograde amnesia
0.633 0.367 0.000
T18 Foreign body in alimentary tract
0.633 0.367 0.000
M54.3 Sciatica
0.633 0.367 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.632 0.368 0.000
E03.8 Other specified hypothyroidism
0.632 0.368 0.000
E03.5 Myxoedema coma
0.632 0.368 0.000
E03.4 Atrophy of thyroid (acquired)
0.632 0.368 0.000
E03.3 Postinfectious hypothyroidism
0.632 0.368 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.632 0.368 0.000
E03.1 Congenital hypothyroidism without goitre
0.632 0.368 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.632 0.368 0.000
G30 Alzheimer's disease
0.632 0.368 0.000
V99 Unspecified transport accident
0.632 0.368 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.631 0.368 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.631 0.369 0.000
Y59 Other and unspecified vaccines and biological substances
0.631 0.369 0.000
Y58 Bacterial vaccines
0.631 0.369 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.631 0.369 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.631 0.369 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.631 0.369 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.631 0.369 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.631 0.369 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.631 0.369 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.631 0.369 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.631 0.369 0.000
M41.96 Scoliosis, unspecified (Lumbar region)
0.631 0.369 0.000
T87.5 Necrosis of amputation stump
0.631 0.369 0.000
T87.3 Neuroma of amputation stump
0.631 0.369 0.000
T87.2 Complications of other reattached body part
0.631 0.369 0.000
T87.1 Complications of reattached (part of) lower extremity
0.631 0.369 0.000
T87.0 Complications of reattached (part of) upper extremity
0.631 0.369 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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