TreeWAS – Variant ID: rs114266608

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
M20-M25 Other joint disorders	1.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
Chapter X Diseases of the respiratory system	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.999	0.001
M20 Acquired deformities of fingers and toes	0.999	0.001
J90-J94 Other diseases of pleura	0.997	0.003
M23 Internal derangement of knee	0.997	0.003
Chapter VII Diseases of the eye and adnexa	0.996	0.004
M23.2 Derangement of meniscus due to old tear or injury	0.995	0.005
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.992	0.008
Chapter XV Pregnancy, childbirth and the puerperium	0.987	0.013
Z50 Care involving use of rehabilitation procedures	0.986	0.014
Z50.1 Other physical therapy	0.984	0.016
J95-J99 Other diseases of the respiratory system	0.983	0.017
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.983	0.017
Chapter XXI Factors influencing health status and contact with health services	0.983	0.017
Z40-Z54 Persons encountering health services for specific procedures and health care	0.980	0.020
Chapter VI Diseases of the nervous system	0.977	0.023
M20.4 Other hammer toe(s) (acquired)	0.975	0.025
J98 Other respiratory disorders	0.973	0.027
O36 Maternal care for other known or suspected foetal problems	0.971	0.029
J98.1 Pulmonary collapse	0.965	0.035
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.960	0.040
H40-H42 Glaucoma	0.958	0.042
M80-M85 Disorders of bone density and structure	0.955	0.045
J90 Pleural effusion, not elsewhere classified	0.955	0.045
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified	0.944	0.056
Chapter XXII Codes for special purposes	0.943	0.057
H40 Glaucoma	0.931	0.069
S40-S49 Injuries to the shoulder and upper arm	0.926	0.074
O36.8 Maternal care for other specified foetal problems	0.921	0.079
M81 Osteoporosis without pathological fracture	0.919	0.081
Chapter XX External causes of morbidity and mortality	0.914	0.086
M20.3 Other deformity of hallux (acquired)	0.914	0.086
G50-G59 Nerve, nerve root and plexus disorders	0.903	0.097
Z46 Fitting and adjustment of other devices	0.903	0.097
M20.5 Other deformities of toe(s) (acquired)	0.900	0.100
M21 Other acquired deformities of limbs	0.899	0.101
M81.9 Osteoporosis, unspecified	0.893	0.107
Z50.5 Speech therapy	0.892	0.108
J93 Pneumothorax	0.890	0.110
T36-T50 Poisoning by drugs, medicaments and biological substances	0.889	0.111
Chapter II Neoplasms	0.889	0.111
S60-S69 Injuries to the wrist and hand	0.887	0.113
S20-S29 Injuries to the thorax	0.885	0.115
G40-G47 Episodic and paroxysmal disorders	0.885	0.115
H53-H54 Visual disturbances and blindness	0.884	0.116
O36.0 Maternal care for rhesus isoimmunisation	0.883	0.117
J91 Pleural effusion in conditions classified elsewhere	0.882	0.118
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.874	0.126
M81.99 Osteoporosis, unspecified (Site unspecified)	0.874	0.126
G90-G99 Other disorders of the nervous system	0.873	0.127
H40.9 Glaucoma, unspecified	0.871	0.129
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.866	0.134
H30-H36 Disorders of choroid and retina	0.863	0.137
J94 Other pleural conditions	0.861	0.139
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.860	0.140
G80-G83 Cerebral palsy and other paralytic syndromes	0.852	0.148
H10-H13 Disorders of conjunctiva	0.851	0.149
S70-S79 Injuries to the hip and thigh	0.850	0.150
S80-S89 Injuries to the knee and lower leg	0.840	0.160
Z46.6 Fitting and adjustment of urinary device	0.838	0.162
J80-J84 Other respiratory diseases principally affecting the interstitium	0.836	0.164
M20.1 Hallux valgus (acquired)	0.835	0.165
O41 Other disorders of amniotic fluid and membranes	0.835	0.165
H55-H59 Other disorders of eye and adnexa	0.833	0.167
Z50.0 Cardiac rehabilitation	0.831	0.169
M22 Disorders of patella	0.828	0.172
J20-J22 Other acute lower respiratory infections	0.826	0.174
O36.5 Maternal care for poor foetal growth	0.825	0.175
O47 False labour	0.825	0.175
J92 Pleural plaque	0.821	0.179
Chapter XI Diseases of the digestive system	0.821	0.179
J60-J70 Lung diseases due to external agents	0.816	0.184
M24 Other specific joint derangements	0.815	0.185
M23.5 Chronic instability of knee	0.811	0.188
J09-J18 Influenza and pneumonia	0.811	0.189
H40.0 Glaucoma suspect	0.811	0.189
U80 Agent resistant to penicillin and related antibiotics	0.810	0.190
H53 Visual disturbances	0.807	0.193
S42 Fracture of shoulder and upper arm	0.804	0.195
O20-O29 Other maternal disorders predominantly related to pregnancy	0.804	0.196
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.804	0.196
T15-T19 Effects of foreign body entering through natural orifice	0.803	0.197
O80-O84 Delivery	0.799	0.200
G57 Mononeuropathies of lower limb	0.799	0.201
M20.6 Acquired deformity of toe(s), unspecified	0.798	0.201
Chapter V Mental and behavioural disorders	0.796	0.204
J93.9 Pneumothorax, unspecified	0.795	0.205
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.792	0.208
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.789	0.211
J40-J47 Chronic lower respiratory diseases	0.788	0.212
X60-X84 Intentional self-harm	0.788	0.212
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.787	0.213
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.786	0.214
G45 Transient cerebral ischaemic attacks and related syndromes	0.785	0.215
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.784	0.216
J98.9 Respiratory disorder, unspecified	0.784	0.216
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.781	0.219
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.779	0.221
T79-T79 Certain early complications of trauma	0.778	0.222
G00-G09 Inflammatory diseases of the central nervous system	0.778	0.222
D00-D09 In situ neoplasms	0.778	0.222
T66-T78 Other and unspecified effects of external causes	0.776	0.224
M65-M68 Disorders of synovium and tendon	0.775	0.225
J44 Other chronic obstructive pulmonary disease	0.774	0.226
X40-X49 Accidental poisoning by and exposure to noxious substances	0.773	0.227
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.773	0.227
O35 Maternal care for known or suspected foetal abnormality and damage	0.772	0.228
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.771	0.229
O42 Premature rupture of membranes	0.771	0.229
M84 Disorders of continuity of bone	0.770	0.230
S22 Fracture of rib(s), sternum and thoracic spine	0.768	0.232
K50-K52 Noninfective enteritis and colitis	0.767	0.233
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.764	0.236
S50-S59 Injuries to the elbow and forearm	0.759	0.241
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.757	0.243
M60-M63 Disorders of muscles	0.757	0.243
C43-C44 Melanoma and other malignant neoplasms of skin	0.756	0.244
Y40 Systemic antibiotics	0.756	0.244
G93 Other disorders of brain	0.756	0.244
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.754	0.246
M20.0 Deformity of finger(s)	0.750	0.250
S10-S19 Injuries to the neck	0.749	0.251
M20.2 Hallux rigidus	0.747	0.253
S46 Injury of muscle and tendon at shoulder and upper arm level	0.746	0.254
Z49 Care involving dialysis	0.746	0.254
M21.3 Wrist or foot drop (acquired)	0.745	0.255
S49 Other and unspecified injuries of shoulder and upper arm	0.743	0.257
Y43 Primarily systemic agents	0.743	0.257
G44 Other headache syndromes	0.743	0.257
H35 Other retinal disorders	0.743	0.257
M86-M90 Other osteopathies	0.742	0.258
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.742	0.258
O32 Maternal care for known or suspected malpresentation of foetus	0.741	0.259
K51 Ulcerative colitis	0.741	0.259
S72 Fracture of femur	0.739	0.261
H43-H45 Disorders of vitreous body and globe	0.734	0.266
O46 Antepartum haemorrhage, not elsewhere classified	0.732	0.268
H25-H28 Disorders of lens	0.732	0.268
O48 Prolonged pregnancy	0.731	0.269
M91-M94 Chondropathies	0.731	0.269
H53.1 Subjective visual disturbances	0.730	0.270
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.729	0.271
S61 Open wound of wrist and hand	0.729	0.271
H40.8 Other glaucoma	0.728	0.272
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.727	0.273
M23.4 Loose body in knee	0.725	0.275
M81.98 Osteoporosis, unspecified (Other)	0.724	0.276
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.723	0.277
U80.1 Methicillin resistant agent	0.721	0.279
M34 Systemic sclerosis	0.720	0.280
C34 Malignant neoplasm of bronchus and lung	0.720	0.280
G59 Mononeuropathy in diseases classified elsewhere	0.720	0.280
M05-M14 Inflammatory polyarthropathies	0.719	0.281
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.719	0.281
Z54 Convalescence	0.719	0.281
W20-W49 Exposure to inanimate mechanical forces	0.718	0.282
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.718	0.282
K70-K77 Diseases of liver	0.718	0.282
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.717	0.283
M33 Dermatopolymyositis	0.717	0.283
M32 Systemic lupus erythematosus	0.717	0.283
M30 Polyarteritis nodosa and related conditions	0.717	0.283
M00-M03 Infectious arthropathies	0.717	0.283
T33-T35 Frostbite	0.716	0.284
T26-T28 Burns and corrosions confined to eye and internal organs	0.716	0.284
T20-T25 Burns and corrosions of external body surface, specified by site	0.716	0.284
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.716	0.284
T00-T07 Injuries involving multiple body regions	0.716	0.284
X20-X29 Contact with venomous animals and plants	0.715	0.285
M23.9 Internal derangement of knee, unspecified	0.714	0.285
M23.6 Other spontaneous disruption of ligament(s) of knee	0.714	0.285
M23.1 Discoid meniscus (congenital)	0.714	0.285
M23.0 Cystic meniscus	0.714	0.285
H46-H48 Disorders of optic nerve and visual pathways	0.714	0.286
J94.8 Other specified pleural conditions	0.714	0.286
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.714	0.286
M22.3 Other derangements of patella	0.713	0.287
C45 Mesothelioma	0.713	0.287
J69 Pneumonitis due to solids and liquids	0.710	0.290
S82 Fracture of lower leg, including ankle	0.710	0.290
K08 Other disorders of teeth and supporting structures	0.709	0.291
O85-O92 Complications predominantly related to the puerperium	0.708	0.292
G70-G73 Diseases of myoneural junction and muscle	0.707	0.293
Z50.6 Orthoptic training	0.707	0.293
Z50.4 Psychotherapy, not elsewhere classified	0.707	0.293
Z50.3 Drug rehabilitation	0.707	0.293
H11 Other disorders of conjunctiva	0.707	0.293
G58 Other mononeuropathies	0.707	0.293
Chapter I Certain infectious and parasitic diseases	0.706	0.294
G83 Other paralytic syndromes	0.706	0.294
M21.6 Other acquired deformities of ankle and foot	0.705	0.295
G43 Migraine	0.705	0.295
J99 Respiratory disorders in diseases classified elsewhere	0.705	0.295
J96 Respiratory failure, not elsewhere classified	0.705	0.295
O45 Premature separation of placenta [abruptio placentae]	0.705	0.295
O44 Placenta praevia	0.705	0.295
O43 Placental disorders	0.705	0.295
O33 Maternal care for known or suspected disproportion	0.705	0.295
O31 Complications specific to multiple gestation	0.705	0.295
O40 Polyhydramnios	0.705	0.295
H57 Other disorders of eye and adnexa	0.704	0.296
G54 Nerve root and plexus disorders	0.703	0.297
M21.0 Valgus deformity, not elsewhere classified	0.703	0.297
Z52 Donors of organs and tissues	0.702	0.297
Z44 Fitting and adjustment of external prosthetic device	0.702	0.297
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.702	0.298
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.701	0.299
Z36 Antenatal screening	0.699	0.301
G45.9 Transient cerebral ischaemic attack, unspecified	0.699	0.301
J98.6 Disorders of diaphragm	0.698	0.302
J98.5 Diseases of mediastinum, not elsewhere classified	0.698	0.302
J98.3 Compensatory emphysema	0.698	0.302
J98.2 Interstitial emphysema	0.698	0.302
J94.2 Haemothorax	0.698	0.302
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.696	0.304
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.696	0.304
O36.6 Maternal care for excessive foetal growth	0.696	0.304
O36.4 Maternal care for intra-uterine death	0.696	0.304
O36.3 Maternal care for signs of foetal hypoxia	0.696	0.304
O36.2 Maternal care for hydrops foetalis	0.696	0.304
O36.1 Maternal care for other isoimmunisation	0.696	0.304
J98.0 Diseases of bronchus, not elsewhere classified	0.696	0.304
M21.1 Varus deformity, not elsewhere classified	0.696	0.304
J84 Other interstitial pulmonary diseases	0.695	0.305
M35 Other systemic involvement of connective tissue	0.693	0.307
S64 Injury of nerves at wrist and hand level	0.692	0.308
S62 Fracture at wrist and hand level	0.691	0.309
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.691	0.309
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.689	0.311
J93.1 Other spontaneous pneumothorax	0.689	0.311
S42.2 Fracture of upper end of humerus	0.688	0.312
O41.0 Oligohydramnios	0.688	0.312
S60 Superficial injury of wrist and hand	0.688	0.312
H42 Glaucoma in diseases classified elsewhere	0.687	0.313
Q80-Q89 Other congenital malformations	0.686	0.314
Z50.8 Care involving use of rehabilitation procedures	0.685	0.315
K13 Other diseases of lip and oral mucosa	0.685	0.315
M83 Adult osteomalacia	0.684	0.315
M82 Osteoporosis in diseases classified elsewhere	0.684	0.315
Z46.8 Fitting and adjustment of other specified devices	0.684	0.315
H40.2 Primary angle-closure glaucoma	0.684	0.316
O36.9 Maternal care for foetal problem, unspecified	0.684	0.316
U80.0 Penicillin resistant agent	0.683	0.317
C51-C58 Malignant neoplasms of female genital organs	0.683	0.317
M24.1 Other articular cartilage disorders	0.683	0.317
J22 Unspecified acute lower respiratory infection	0.683	0.317
M40-M43 Deforming dorsopathies	0.679	0.320
J92.9 Pleural plaque without asbestos	0.679	0.321
Q38-Q45 Other congenital malformations of the digestive system	0.679	0.321
S90-S99 Injuries to the ankle and foot	0.679	0.321
M45-M49 Spondylopathies	0.679	0.321
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.679	0.321
O47.9 False labour, unspecified	0.678	0.321
S20 Superficial injury of thorax	0.678	0.322
G90 Disorders of autonomic nervous system	0.677	0.323
G81 Hemiplegia	0.676	0.324
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.676	0.324
H10 Conjunctivitis	0.676	0.324
J98.8 Other specified respiratory disorders	0.675	0.325
O30 Multiple gestation	0.675	0.325
Y51 Drugs primarily affecting the autonomic nervous system	0.675	0.325
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.674	0.326
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.673	0.327
S27 Injury of other and unspecified intrathoracic organs	0.673	0.327
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified	0.672	0.328
F30-F39 Mood [affective] disorders	0.672	0.328
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.671	0.329
J15 Bacterial pneumonia, not elsewhere classified	0.671	0.329
J44.9 Chronic obstructive pulmonary disease, unspecified	0.671	0.329
G57.1 Meralgia paraesthetica	0.671	0.329
J98.4 Other disorders of lung	0.670	0.330
G91 Hydrocephalus	0.669	0.331
H34 Retinal vascular occlusions	0.669	0.331
H40.6 Glaucoma secondary to drugs	0.667	0.333
H40.5 Glaucoma secondary to other eye disorders	0.667	0.333
H40.4 Glaucoma secondary to eye inflammation	0.667	0.333
H40.3 Glaucoma secondary to eye trauma	0.667	0.333
Z50.2 Alcohol rehabilitation	0.667	0.333
H40.1 Primary open-angle glaucoma	0.667	0.333
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.666	0.333
S82.6 Fracture of lateral malleolus	0.666	0.334
O20 Haemorrhage in early pregnancy	0.666	0.334
G57.6 Lesion of plantar nerve	0.666	0.334
G40 Epilepsy	0.665	0.335
S81 Open wound of lower leg	0.665	0.335
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.665	0.335
Z43 Attention to artificial openings	0.665	0.335
T18 Foreign body in alimentary tract	0.665	0.335
S48 Traumatic amputation of shoulder and upper arm	0.664	0.336
S45 Injury of blood vessels at shoulder and upper arm level	0.664	0.336
S44 Injury of nerves at shoulder and upper arm level	0.664	0.336
S41 Open wound of shoulder and upper arm	0.664	0.336
S40 Superficial injury of shoulder and upper arm	0.664	0.336
S47 Crushing injury of shoulder and upper arm	0.664	0.336
O41.8 Other specified disorders of amniotic fluid and membranes	0.663	0.337
J95 Postprocedural respiratory disorders, not elsewhere classified	0.662	0.338
D05 Carcinoma in situ of breast	0.661	0.339
Y52 Agents primarily affecting the cardiovascular system	0.661	0.339
C45.0 Mesothelioma of pleura	0.660	0.340
S61.8 Open wound of other parts of wrist and hand	0.660	0.340
H26 Other cataract	0.660	0.340
S42.0 Fracture of clavicle	0.660	0.340
U88 Agent resistant to multiple antibiotics	0.659	0.340
M81.8 Other osteoporosis	0.659	0.341
M81.6 Localised osteoporosis [Lequesne]	0.659	0.341
M81.5 Idiopathic osteoporosis	0.659	0.341
M81.4 Drug-induced osteoporosis	0.659	0.341
M81.3 Postsurgical malabsorption osteoporosis	0.659	0.341
M81.2 Osteoporosis of disuse	0.659	0.341
M81.1 Postoophorectomy osteoporosis	0.659	0.341
M81.0 Postmenopausal osteoporosis	0.659	0.341
O80 Single spontaneous delivery	0.659	0.341
K51.2 Ulcerative (chronic) proctitis	0.658	0.341
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.657	0.343
T43.0 Tricyclic and tetracyclic antidepressants	0.657	0.343
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.655	0.345
Y35-Y36 Legal intervention and operations of war	0.655	0.345
Y10-Y34 Event of undetermined intent	0.655	0.345
Y00-Y09 Assault	0.655	0.345
X85-X99 Assault	0.655	0.345
X58-X59 Accidental exposure to other and unspecified factors	0.655	0.345
X50-X57 Overexertion, travel and privation	0.655	0.345
X30-X39 Exposure to forces of nature	0.655	0.345
X10-X19 Contact with heat and hot substances	0.655	0.345
X00-X09 Exposure to smoke, fire and flames	0.655	0.345
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.655	0.345
W75-W84 Other accidental threats to breathing	0.655	0.345
W65-W74 Accidental drowning and submersion	0.655	0.345
W50-W64 Exposure to animate mechanical forces	0.655	0.345
V98-V99 Other and unspecified transport accidents	0.655	0.345
V95-V97 Air and space transport accidents	0.655	0.345
V90-V94 Water transport accidents	0.655	0.345
V80-V89 Other land transport accidents	0.655	0.345
V70-V79 Bus occupant injured in transport accident	0.655	0.345
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.655	0.345
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.655	0.345
V40-V49 Car occupant injured in transport accident	0.655	0.345
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.655	0.345
V20-V29 Motorcycle rider injured in transport accident	0.655	0.345
V01-V09 Pedestrian injured in transport accident	0.655	0.345
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.654	0.346
K51.9 Ulcerative colitis, unspecified	0.653	0.347
K35-K38 Diseases of appendix	0.652	0.348
S22.3 Fracture of rib	0.651	0.349
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.651	0.349
Y40.9 Systemic antibiotic, unspecified	0.649	0.350
Z48 Other surgical follow-up care	0.649	0.351
G51 Facial nerve disorders	0.648	0.352
D37-D48 Neoplasms of uncertain or unknown behaviour	0.648	0.352
G53 Cranial nerve disorders in diseases classified elsewhere	0.647	0.353
G52 Disorders of other cranial nerves	0.647	0.353
Z46.9 Fitting and adjustment of other unspecified device	0.647	0.353
Z46.7 Fitting and adjustment of orthopaedic device	0.647	0.353
Z46.5 Fitting and adjustment of ileostomy and other intestinal appliances	0.647	0.353
Z46.4 Fitting and adjustment of orthodontic device	0.647	0.353
Z46.3 Fitting and adjustment of dental prosthetic device	0.647	0.353
Z46.2 Fitting and adjustment of other devices related to nervous system and special senses	0.647	0.353
Z46.1 Fitting and adjustment of hearing aid	0.647	0.353
Z46.0 Fitting and adjustment of spectacles and contact lenses	0.647	0.353
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.647	0.353
C44 Other malignant neoplasms of skin	0.646	0.354
U89 Agent resistant to other and unspecified antibiotics	0.646	0.354
H35.2 Other proliferative retinopathy	0.646	0.354
M80 Osteoporosis with pathological fracture	0.645	0.355
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.645	0.355
M21.9 Acquired deformity of limb, unspecified	0.645	0.355
M21.8 Other specified acquired deformities of limbs	0.645	0.355
M21.7 Unequal limb length (acquired)	0.645	0.355
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.645	0.355
M21.4 Flat foot [pes planus] (acquired)	0.645	0.355
M21.2 Flexion deformity	0.645	0.355
Q60-Q64 Congenital malformations of the urinary system	0.644	0.355
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system	0.644	0.356
F99-F99 Unspecified mental disorder	0.643	0.357
H53.2 Diplopia	0.643	0.357
M85 Other disorders of bone density and structure	0.643	0.357
D03 Melanoma in situ	0.642	0.358
O47.1 False labour at or after 37 completed weeks of gestation	0.642	0.358
G44.2 Tension-type headache	0.641	0.359
G50 Disorders of trigeminal nerve	0.641	0.359
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.641	0.359
M81.96 Osteoporosis, unspecified (Lower leg)	0.641	0.359
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.641	0.359
M81.94 Osteoporosis, unspecified (Hand)	0.641	0.359
M81.93 Osteoporosis, unspecified (Forearm)	0.641	0.359
M81.92 Osteoporosis, unspecified (Upper arm)	0.641	0.359
M81.91 Osteoporosis, unspecified (Shoulder region)	0.641	0.359
Q20-Q28 Congenital malformations of the circulatory system	0.640	0.360
F60-F69 Disorders of adult personality and behaviour	0.640	0.360
Y57 Other and unspecified drugs and medicaments	0.640	0.360
G99 Other disorders of nervous system in diseases classified elsewhere	0.640	0.360
Z33 Pregnant state, incidental	0.640	0.360
S72.0 Fracture of neck of femur	0.639	0.361
G80 Infantile cerebral palsy	0.639	0.361
J93.8 Other pneumothorax	0.638	0.361
J93.0 Spontaneous tension pneumothorax	0.638	0.361
J81 Pulmonary oedema	0.638	0.362
J86 Pyothorax	0.638	0.362
M84.1 Nonunion of fracture [pseudarthrosis]	0.638	0.362
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.637	0.363
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.637	0.363
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.637	0.363
T46 Poisoning by agents primarily affecting the cardiovascular system	0.637	0.363
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.637	0.363
T41 Poisoning by anaesthetics and therapeutic gases	0.637	0.363
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.637	0.363
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.637	0.363
T36 Poisoning by systemic antibiotics	0.637	0.363
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.637	0.363
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.637	0.363
C40-C41 Malignant neoplasms of bone and articular cartilage	0.637	0.363
H53.9 Visual disturbance, unspecified	0.636	0.364
S69 Other and unspecified injuries of wrist and hand	0.636	0.364
S67 Crushing injury of wrist and hand	0.636	0.364
S65 Injury of blood vessels at wrist and hand level	0.636	0.364
Y44 Agents primarily affecting blood constituents	0.636	0.364
Z29 Need for other prophylactic measures	0.636	0.364
S82.60 Fracture of lateral malleolus (closed)	0.636	0.364
G04 Encephalitis, myelitis and encephalomyelitis	0.635	0.365
J69.0 Pneumonitis due to food and vomit	0.635	0.365
M31 Other necrotising vasculopathies	0.635	0.365
S29 Other and unspecified injuries of thorax	0.634	0.365
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.634	0.365
S26 Injury of heart	0.634	0.365
S25 Injury of blood vessels of thorax	0.634	0.365
S24 Injury of nerves and spinal cord at thorax level	0.634	0.365
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.634	0.365
S21 Open wound of thorax	0.634	0.365
G46 Vascular syndromes of brain in cerebrovascular diseases	0.634	0.366
G41 Status epilepticus	0.634	0.366
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.634	0.366
M23.8 Other internal derangements of knee	0.634	0.366
Z42 Follow-up care involving plastic surgery	0.634	0.366
H36 Retinal disorders in diseases classified elsewhere	0.633	0.367
K08.3 Retained dental root	0.631	0.369
T90 Sequelae of injuries of head	0.628	0.371
Q00-Q07 Congenital malformations of the nervous system	0.628	0.372
Y59 Other and unspecified vaccines and biological substances	0.627	0.373
Y58 Bacterial vaccines	0.627	0.373
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.627	0.373
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.627	0.373
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.627	0.373
Y53 Agents primarily affecting the gastro-intestinal system	0.627	0.373
Y50 Central nervous system stimulants, not elsewhere classified	0.627	0.373
Y49 Psychotropic drugs, not elsewhere classified	0.627	0.373
Y48 Anaesthetics and therapeutic gases	0.627	0.373
Y47 Sedatives, hypnotics and antianxiety drugs	0.627	0.373
Y46 Antiepileptics and anti-Parkinsonism drugs	0.627	0.373
Y41 Other systemic anti-infectives and antiparasitics	0.627	0.373
H20 Iridocyclitis	0.627	0.373
S68 Traumatic amputation of wrist and hand	0.626	0.374
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.626	0.374
G96 Other disorders of central nervous system	0.626	0.374
G94 Other disorders of brain in diseases classified elsewhere	0.626	0.374
G98 Other disorders of nervous system, not elsewhere classified	0.626	0.374
G92 Toxic encephalopathy	0.626	0.374
U80.8 Agent resistant to other penicillin-related antibiotic	0.624	0.376
J20 Acute bronchitis	0.623	0.376
H54 Blindness and low vision	0.622	0.378
G82 Paraplegia and tetraplegia	0.621	0.379
U81 Agent resistant to vancomycin and related antibiotics	0.621	0.379
U51 Admission status on psychiatric patients	0.621	0.379
U50 Level of care administered to neonates	0.621	0.379
U07 Emergency use of U07	0.621	0.379
U06 Emergency use of U06	0.621	0.379
U04 Severe acute respiratory syndrome [SARS]	0.621	0.379
U52 First in a series of a regular day/night admissions	0.621	0.379
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.620	0.379
G95 Other diseases of spinal cord	0.620	0.380
T79 Certain early complications of trauma, not elsewhere classified	0.619	0.381
H32 Chorioretinal disorders in diseases classified elsewhere	0.619	0.381
H31 Other disorders of choroid	0.619	0.381
H30 Chorioretinal inflammation	0.619	0.381
Z50.9 Care involving use of rehabilitation procedure, unspecified	0.618	0.382
K13.7 Other and unspecified lesions of oral mucosa	0.618	0.382
J18 Pneumonia, organism unspecified	0.618	0.382
J94.9 Pleural condition, unspecified	0.617	0.383
J94.1 Fibrothorax	0.617	0.383
J94.0 Chylous effusion	0.617	0.383
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.617	0.383
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.617	0.383
Q35-Q37 Cleft lip and cleft palate	0.617	0.383
Q30-Q34 Congenital malformations of the respiratory system	0.617	0.383
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.617	0.383
J10 Influenza due to identified influenza virus	0.616	0.383
S70 Superficial injury of hip and thigh	0.616	0.384
C15-C26 Malignant neoplasms of digestive organs	0.616	0.384
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.615	0.384
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.615	0.384
K12 Stomatitis and related lesions	0.615	0.385
K90-K93 Other diseases of the digestive system	0.615	0.385
C44.5 Skin of trunk	0.615	0.385
Q50-Q56 Congenital malformations of genital organs	0.614	0.386
H35.0 Background retinopathy and retinal vascular changes	0.614	0.386
M22.2 Patellofemoral disorders	0.613	0.387
J92.0 Pleural plaque with presence of asbestos	0.613	0.387

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations