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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs114280567
log Bayes Factor = 5.46027
Chromosome 13   position 45,475,582  (GRCh37) Explore rs114280567 on Ensembl!
Variant rs114280567 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
0.997 0.003 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.989 0.011 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.980 0.020 0.000
Chapter XIV Diseases of the genitourinary system
0.973 0.027 0.000
Chapter II Neoplasms
0.967 0.033 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.966 0.034 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.964 0.036 0.000
Chapter XI Diseases of the digestive system
0.957 0.043 0.000
M15-M19 Arthrosis
0.937 0.063 0.000
N30-N39 Other diseases of urinary system
0.920 0.080 0.000
M20-M25 Other joint disorders
0.907 0.093 0.000
Z85 Personal history of malignant neoplasm
0.900 0.100 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.890 0.110 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.886 0.114 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.880 0.120 0.000
Chapter IX Diseases of the circulatory system
0.878 0.122 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.875 0.125 0.000
Z46 Fitting and adjustment of other devices
0.869 0.130 0.000
R30-R39 Symptoms and signs involving the urinary system
0.865 0.135 0.000
N39 Other disorders of urinary system
0.853 0.147 0.000
Z51 Other medical care
0.850 0.150 0.000
Z87 Personal history of other diseases and conditions
0.847 0.153 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.846 0.154 0.000
C60-C63 Malignant neoplasms of male genital organs
0.835 0.165 0.000
D10-D36 Benign neoplasms
0.830 0.170 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.829 0.171 0.000
K55-K64 Other diseases of intestines
0.827 0.172 0.000
N00-N08 Glomerular diseases
0.824 0.176 0.000
M16 Coxarthrosis [arthrosis of hip]
0.823 0.177 0.000
M17 Gonarthrosis [arthrosis of knee]
0.812 0.188 0.000
N39.0 Urinary tract infection, site not specified
0.803 0.197 0.000
Z46.6 Fitting and adjustment of urinary device
0.802 0.198 0.000
Chapter V Mental and behavioural disorders
0.799 0.201 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.795 0.205 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.793 0.207 0.000
Z80 Family history of malignant neoplasm
0.788 0.212 0.000
N32 Other disorders of bladder
0.785 0.215 0.000
Z50 Care involving use of rehabilitation procedures
0.778 0.222 0.000
L60-L75 Disorders of skin appendages
0.776 0.224 0.000
Chapter VI Diseases of the nervous system
0.775 0.225 0.000
M20 Acquired deformities of fingers and toes
0.775 0.225 0.000
E65-E68 Obesity and other hyperalimentation
0.772 0.228 0.000
Chapter VIII Diseases of the ear and mastoid process
0.770 0.230 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.770 0.230 0.000
M80-M85 Disorders of bone density and structure
0.769 0.231 0.000
K82 Other diseases of gallbladder
0.767 0.233 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.766 0.233 0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems
0.765 0.235 0.000
M45-M49 Spondylopathies
0.762 0.238 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.756 0.244 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.755 0.245 0.000
I30-I52 Other forms of heart disease
0.755 0.245 0.000
Chapter I Certain infectious and parasitic diseases
0.755 0.245 0.000
M19 Other arthrosis
0.754 0.246 0.000
R50-R69 General symptoms and signs
0.753 0.247 0.000
N25-N29 Other disorders of kidney and ureter
0.753 0.247 0.000
Z51.2 Other chemotherapy
0.752 0.248 0.000
Z96 Presence of other functional implants
0.751 0.249 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.747 0.252 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.747 0.253 0.000
M25 Other joint disorders, not elsewhere classified
0.746 0.253 0.000
M05-M14 Inflammatory polyarthropathies
0.746 0.254 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.744 0.256 0.000
C61 Malignant neoplasm of prostate
0.741 0.259 0.000
R11 Nausea and vomiting
0.741 0.259 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.741 0.259 0.000
K80 Cholelithiasis
0.739 0.261 0.000
M16.9 Coxarthrosis, unspecified
0.738 0.262 0.000
R32 Unspecified urinary incontinence
0.737 0.263 0.000
Z47 Other orthopaedic follow-up care
0.737 0.263 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.736 0.263 0.000
M50-M54 Other dorsopathies
0.734 0.266 0.000
Z85.5 Personal history of malignant neoplasm of urinary tract
0.734 0.266 0.000
M17.9 Gonarthrosis, unspecified
0.732 0.268 0.000
C15-C26 Malignant neoplasms of digestive organs
0.731 0.269 0.000
C64-C68 Malignant neoplasms of urinary tract
0.730 0.270 0.000
N60-N64 Disorders of breast
0.728 0.272 0.000
D00-D09 In situ neoplasms
0.727 0.273 0.000
Z98 Other postsurgical states
0.726 0.274 0.000
Chapter XX External causes of morbidity and mortality
0.725 0.275 0.000
N40-N51 Diseases of male genital organs
0.725 0.275 0.000
M23 Internal derangement of knee
0.723 0.277 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.718 0.282 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.718 0.282 0.000
N03 Chronic nephritic syndrome
0.717 0.282 0.000
Chapter XXII Codes for special purposes
0.717 0.283 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M70-M79 Other soft tissue disorders
0.716 0.284 0.000
K65-K67 Diseases of peritoneum
0.715 0.285 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.715 0.285 0.000
Z90.1 Acquired absence of breast(s)
0.715 0.285 0.000
K50-K52 Noninfective enteritis and colitis
0.713 0.287 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.712 0.288 0.000
Z87.4 Personal history of diseases of the genito-urinary system
0.710 0.290 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.709 0.291 0.000
M91-M94 Chondropathies
0.709 0.291 0.000
M86-M90 Other osteopathies
0.709 0.291 0.000
M65-M68 Disorders of synovium and tendon
0.709 0.291 0.000
M60-M63 Disorders of muscles
0.709 0.291 0.000
M40-M43 Deforming dorsopathies
0.709 0.291 0.000
M00-M03 Infectious arthropathies
0.709 0.291 0.000
Z51.0 Radiotherapy session
0.709 0.291 0.000
K90-K93 Other diseases of the digestive system
0.708 0.291 0.000
C50-C50 Malignant neoplasm of breast
0.708 0.292 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.706 0.294 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.706 0.294 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.703 0.297 0.000
Z97 Presence of other devices
0.703 0.297 0.000
Z94 Transplanted organ and tissue status
0.703 0.297 0.000
Z93 Artificial opening status
0.703 0.297 0.000
Z89 Acquired absence of limb
0.703 0.297 0.000
Z84 Family history of other conditions
0.703 0.297 0.000
Z83 Family history of other specific disorders
0.703 0.297 0.000
Z81 Family history of mental and behavioural disorders
0.703 0.297 0.000
O60-O75 Complications of labour and delivery
0.702 0.298 0.000
E00-E07 Disorders of thyroid gland
0.701 0.298 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.698 0.302 0.000
N99-N99 Other disorders of the genitourinary system
0.698 0.302 0.000
N10-N16 Renal tubulo-interstitial diseases
0.698 0.302 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.697 0.303 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.697 0.303 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.693 0.307 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.693 0.307 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.693 0.307 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.693 0.307 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.693 0.307 0.000
C51-C58 Malignant neoplasms of female genital organs
0.693 0.307 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.693 0.307 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.693 0.307 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.693 0.307 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.692 0.308 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.692 0.308 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.692 0.308 0.000
R47-R49 Symptoms and signs involving speech and voice
0.692 0.308 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.692 0.308 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.692 0.308 0.000
Z54 Convalescence
0.691 0.309 0.000
Z52 Donors of organs and tissues
0.691 0.309 0.000
Z49 Care involving dialysis
0.691 0.309 0.000
Z48 Other surgical follow-up care
0.691 0.309 0.000
Z45 Adjustment and management of implanted device
0.691 0.309 0.000
Z44 Fitting and adjustment of external prosthetic device
0.691 0.309 0.000
Z43 Attention to artificial openings
0.691 0.309 0.000
Z42 Follow-up care involving plastic surgery
0.691 0.309 0.000
Z41 Procedures for purposes other than remedying health state
0.691 0.309 0.000
Z40 Prophylactic surgery
0.691 0.309 0.000
L40-L45 Papulosquamous disorders
0.691 0.309 0.000
K82.8 Other specified diseases of gallbladder
0.689 0.311 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.689 0.311 0.000
K58 Irritable bowel syndrome
0.688 0.312 0.000
E66 Obesity
0.687 0.313 0.000
K70-K77 Diseases of liver
0.686 0.314 0.000
K35-K38 Diseases of appendix
0.686 0.314 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.686 0.314 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.685 0.315 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.683 0.317 0.000
E10-E14 Diabetes mellitus
0.683 0.317 0.000
R31 Unspecified haematuria
0.681 0.319 0.000
Z95.0 Presence of cardiac pacemaker
0.681 0.319 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.680 0.320 0.000
Z86 Personal history of certain other diseases
0.677 0.323 0.000
R35 Polyuria
0.675 0.325 0.000
N20-N23 Urolithiasis
0.673 0.327 0.000
N17-N19 Renal failure
0.673 0.327 0.000
M18 Arthrosis of first carpometacarpal joint
0.672 0.328 0.000
M15 Polyarthrosis
0.672 0.328 0.000
Z85.4 Personal history of malignant neoplasm of genital organs
0.667 0.333 0.000
N32.8 Other specified disorders of bladder
0.666 0.334 0.000
K62 Other diseases of anus and rectum
0.665 0.335 0.000
I50 Heart failure
0.665 0.335 0.000
Z90.7 Acquired absence of genital organ(s)
0.664 0.335 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.663 0.337 0.000
O00-O08 Pregnancy with abortive outcome
0.661 0.339 0.000
N37 Urethral disorders in diseases classified elsewhere
0.659 0.341 0.000
N36 Other disorders of urethra
0.659 0.341 0.000
N34 Urethritis and urethral syndrome
0.659 0.341 0.000
N33 Bladder disorders in diseases classified elsewhere
0.659 0.341 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.659 0.341 0.000
N30 Cystitis
0.659 0.341 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.658 0.342 0.000
Chapter VII Diseases of the eye and adnexa
0.658 0.342 0.000
D24 Benign neoplasm of breast
0.658 0.342 0.000
R15 Faecal incontinence
0.657 0.343 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.652 0.348 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.650 0.350 0.000
M35 Other systemic involvement of connective tissue
0.650 0.350 0.000
M34 Systemic sclerosis
0.650 0.350 0.000
M33 Dermatopolymyositis
0.650 0.350 0.000
M32 Systemic lupus erythematosus
0.650 0.350 0.000
M31 Other necrotising vasculopathies
0.650 0.350 0.000
M30 Polyarteritis nodosa and related conditions
0.650 0.350 0.000
M24 Other specific joint derangements
0.650 0.350 0.000
M22 Disorders of patella
0.650 0.350 0.000
M21 Other acquired deformities of limbs
0.650 0.350 0.000
Z80.0 Family history of malignant neoplasm of digestive organs
0.650 0.350 0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue
0.649 0.350 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.648 0.352 0.000
Z85.0 Personal history of malignant neoplasm of digestive organs
0.645 0.355 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.645 0.355 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.645 0.355 0.000
Z85.6 Personal history of leukaemia
0.645 0.355 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.645 0.355 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.645 0.355 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.645 0.355 0.000
Z50.1 Other physical therapy
0.645 0.355 0.000
Z87.1 Personal history of diseases of the digestive system
0.644 0.356 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.642 0.357 0.000
Chapter X Diseases of the respiratory system
0.642 0.358 0.000
N03.9 Unspecified
0.641 0.359 0.000
L72.1 Trichilemmal cyst
0.641 0.359 0.000
K40-K46 Hernia
0.638 0.362 0.000
E50-E64 Other nutritional deficiencies
0.638 0.362 0.000
E40-E46 Malnutrition
0.638 0.362 0.000
E20-E35 Disorders of other endocrine glands
0.638 0.362 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.638 0.362 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.635 0.364 0.000
L50-L54 Urticaria and erythema
0.635 0.364 0.000
L20-L30 Dermatitis and eczema
0.635 0.364 0.000
L10-L14 Bullous disorders
0.635 0.364 0.000
G20-G26 Extrapyramidal and movement disorders
0.633 0.367 0.000
I60-I69 Cerebrovascular diseases
0.632 0.368 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.632 0.368 0.000
Z90.8 Acquired absence of other organs
0.631 0.369 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.631 0.369 0.000
Z90.5 Acquired absence of kidney
0.631 0.369 0.000
Z90.3 Acquired absence of part of stomach
0.631 0.369 0.000
Z90.2 Acquired absence of lung [part of]
0.631 0.369 0.000
Z90.0 Acquired absence of part of head and neck
0.631 0.369 0.000
I05-I09 Chronic rheumatic heart diseases
0.629 0.370 0.000
I00-I02 Acute rheumatic fever
0.629 0.370 0.000
N39.3 Stress incontinence
0.628 0.372 0.000
R33 Retention of urine
0.627 0.373 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.627 0.373 0.000
K86 Other diseases of pancreas
0.627 0.373 0.000
K85 Acute pancreatitis
0.627 0.373 0.000
K83 Other diseases of biliary tract
0.627 0.373 0.000
K81 Cholecystitis
0.627 0.373 0.000
N35 Urethral stricture
0.626 0.374 0.000
E66.9 Obesity, unspecified
0.626 0.374 0.000
Z46.9 Fitting and adjustment of other unspecified device
0.623 0.376 0.000
Z46.8 Fitting and adjustment of other specified devices
0.623 0.376 0.000
Z46.7 Fitting and adjustment of orthopaedic device
0.623 0.376 0.000
Z46.5 Fitting and adjustment of ileostomy and other intestinal appliances
0.623 0.376 0.000
Z46.4 Fitting and adjustment of orthodontic device
0.623 0.376 0.000
Z46.3 Fitting and adjustment of dental prosthetic device
0.623 0.376 0.000
Z46.2 Fitting and adjustment of other devices related to nervous system and special senses
0.623 0.376 0.000
Z46.1 Fitting and adjustment of hearing aid
0.623 0.376 0.000
Z46.0 Fitting and adjustment of spectacles and contact lenses
0.623 0.376 0.000
M19.9 Arthrosis, unspecified
0.623 0.377 0.000
C44 Other malignant neoplasms of skin
0.623 0.377 0.000
K60 Fissure and fistula of anal and rectal regions
0.622 0.378 0.000
R39 Other symptoms and signs involving the urinary system
0.620 0.379 0.000
R30 Pain associated with micturition
0.620 0.380 0.000
R36 Urethral discharge
0.620 0.380 0.000
R34 Anuria and oliguria
0.620 0.380 0.000
E70-E90 Metabolic disorders
0.617 0.383 0.000
I10-I15 Hypertensive diseases
0.617 0.383 0.000
I84 Haemorrhoids
0.616 0.384 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.616 0.384 0.000
N39.9 Disorder of urinary system, unspecified
0.612 0.388 0.000
N39.8 Other specified disorders of urinary system
0.612 0.388 0.000
N39.4 Other specified urinary incontinence
0.612 0.388 0.000
N39.2 Orthostatic proteinuria, unspecified
0.612 0.388 0.000
N39.1 Persistent proteinuria, unspecified
0.612 0.388 0.000
K63 Other diseases of intestine
0.612 0.388 0.000
M81 Osteoporosis without pathological fracture
0.612 0.388 0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.611 0.388 0.000
M20.1 Hallux valgus (acquired)
0.611 0.389 0.000
Z51.1 Chemotherapy session for neoplasm
0.611 0.389 0.000
K21 Gastro-oesophageal reflux disease
0.610 0.390 0.000
M20.2 Hallux rigidus
0.610 0.390 0.000
Z51.9 Medical care, unspecified
0.609 0.391 0.000
Z51.8 Other specified medical care
0.609 0.391 0.000
Z51.6 Desensitisation to allergens
0.609 0.391 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.609 0.391 0.000
Z51.3 Blood transfusion without reported diagnosis
0.609 0.391 0.000
K80.1 Calculus of gallbladder with other cholecystitis
0.608 0.392 0.000
Z87.8 Personal history of other specified conditions
0.607 0.393 0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities
0.607 0.393 0.000
Z87.6 Personal history of certain conditions arising in the perinatal period
0.607 0.393 0.000
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium
0.607 0.393 0.000
Z87.2 Personal history of diseases of the skin and subcutaneous tissue
0.607 0.393 0.000
Z87.0 Personal history of diseases of the respiratory system
0.607 0.393 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.607 0.393 0.000
M20.4 Other hammer toe(s) (acquired)
0.607 0.393 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.606 0.394 0.000
O85-O92 Complications predominantly related to the puerperium
0.606 0.394 0.000
O80-O84 Delivery
0.606 0.394 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.606 0.394 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.606 0.394 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.606 0.394 0.000
H90-H95 Other disorders of ear
0.605 0.395 0.000
N32.0 Bladder-neck obstruction
0.604 0.396 0.000
R00 Abnormalities of heart beat
0.604 0.396 0.000
Z30 Contraceptive management
0.601 0.399 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.600 0.400 0.000
N95 Menopausal and other perimenopausal disorders
0.599 0.401 0.000
C63 Malignant neoplasm of other and unspecified male genital organs
0.599 0.401 0.000
C62 Malignant neoplasm of testis
0.599 0.401 0.000
C60 Malignant neoplasm of penis
0.599 0.401 0.000
M47 Spondylosis
0.598 0.402 0.000
R63 Symptoms and signs concerning food and fluid intake
0.597 0.402 0.000
N80 Endometriosis
0.597 0.403 0.000
R13 Dysphagia
0.596 0.404 0.000
Z96.6 Presence of orthopaedic joint implants
0.596 0.404 0.000
M16.1 Other primary coxarthrosis
0.596 0.404 0.000
D36 Benign neoplasm of other and unspecified sites
0.595 0.405 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.595 0.405 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.595 0.405 0.000
D32 Benign neoplasm of meninges
0.595 0.405 0.000
D31 Benign neoplasm of eye and adnexa
0.595 0.405 0.000
D30 Benign neoplasm of urinary organs
0.595 0.405 0.000
D29 Benign neoplasm of male genital organs
0.595 0.405 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.595 0.405 0.000
D26 Other benign neoplasms of uterus
0.595 0.405 0.000
D23 Other benign neoplasms of skin
0.595 0.405 0.000
D22 Melanocytic naevi
0.595 0.405 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.595 0.405 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.595 0.405 0.000
D19 Benign neoplasm of mesothelial tissue
0.595 0.405 0.000
D18 Haemangioma and lymphangioma, any site
0.595 0.405 0.000
D17 Benign lipomatous neoplasm
0.595 0.405 0.000
D16 Benign neoplasm of bone and articular cartilage
0.595 0.405 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.595 0.405 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.595 0.405 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.595 0.405 0.000
D11 Benign neoplasm of major salivary glands
0.595 0.405 0.000
D10 Benign neoplasm of mouth and pharynx
0.595 0.405 0.000
D34 Benign neoplasm of thyroid gland
0.595 0.405 0.000
D27 Benign neoplasm of ovary
0.595 0.405 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.594 0.406 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.594 0.406 0.000
R18 Ascites
0.594 0.406 0.000
R17 Unspecified jaundice
0.594 0.406 0.000
R14 Flatulence and related conditions
0.594 0.406 0.000
R12 Heartburn
0.594 0.406 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.594 0.406 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.593 0.407 0.000
K61 Abscess of anal and rectal regions
0.593 0.407 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.593 0.407 0.000
K55 Vascular disorders of intestine
0.593 0.407 0.000
A00-A09 Intestinal infectious diseases
0.593 0.407 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.592 0.407 0.000
M25.7 Osteophyte
0.591 0.409 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.591 0.409 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.591 0.409 0.000
N06 Isolated proteinuria with specified morphological lesion
0.591 0.409 0.000
N05 Unspecified nephritic syndrome
0.591 0.409 0.000
N04 Nephrotic syndrome
0.591 0.409 0.000
N02 Recurrent and persistent haematuria
0.591 0.409 0.000
N01 Rapidly progressive nephritic syndrome
0.591 0.409 0.000
N00 Acute nephritic syndrome
0.591 0.409 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.591 0.409 0.000
M25.5 Pain in joint
0.590 0.410 0.000
M16.7 Other secondary coxarthrosis
0.590 0.410 0.000
M16.6 Other secondary coxarthrosis, bilateral
0.590 0.410 0.000
M16.5 Other posttraumatic coxarthrosis
0.590 0.410 0.000
M16.4 Posttraumatic coxarthrosis, bilateral
0.590 0.410 0.000
M16.3 Other dysplastic coxarthrosis
0.590 0.410 0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral
0.590 0.410 0.000
M16.0 Primary coxarthrosis, bilateral
0.590 0.410 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.588 0.412 0.000
K58.9 Irritable bowel syndrome without diarrhoea
0.588 0.412 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.587 0.413 0.000
R79 Other abnormal findings of blood chemistry
0.585 0.415 0.000
R53 Malaise and fatigue
0.584 0.416 0.000
K59 Other functional intestinal disorders
0.583 0.417 0.000
I95 Hypotension
0.583 0.417 0.000
M17.5 Other secondary gonarthrosis
0.582 0.418 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.582 0.418 0.000
M17.3 Other posttraumatic gonarthrosis
0.582 0.418 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.582 0.418 0.000
M17.0 Primary gonarthrosis, bilateral
0.582 0.418 0.000
I50.1 Left ventricular failure
0.582 0.418 0.000
N50 Other disorders of male genital organs
0.580 0.419 0.000
C34 Malignant neoplasm of bronchus and lung
0.580 0.420 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.579 0.420 0.000
D25 Leiomyoma of uterus
0.576 0.423 0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device
0.574 0.426 0.000
F99-F99 Unspecified mental disorder
0.573 0.427 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.573 0.427 0.000
F80-F89 Disorders of psychological development
0.573 0.427 0.000
F70-F79 Mental retardation
0.573 0.427 0.000
F60-F69 Disorders of adult personality and behaviour
0.573 0.427 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.573 0.427 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.573 0.427 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.573 0.427 0.000
G40-G47 Episodic and paroxysmal disorders
0.571 0.429 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.570 0.430 0.000
Z95.4 Presence of other heart-valve replacement
0.570 0.430 0.000
Z95.3 Presence of xenogenic heart valve
0.570 0.430 0.000
Z95.2 Presence of prosthetic heart valve
0.570 0.430 0.000
Z92 Personal history of medical treatment
0.569 0.431 0.000
Z91.8 Personal history of other specified risk-factors, not elsewhere classified
0.568 0.431 0.000
Z91.7 Personal history of female genital mutilation
0.568 0.431 0.000
Z91.6 Personal history of other physical trauma
0.568 0.431 0.000
Z91.5 Personal history of self-harm
0.568 0.431 0.000
Z91.4 Personal history of psychological trauma, not elsewhere classified
0.568 0.431 0.000
Z91.3 Personal history of unhealthy sleep-wake schedule
0.568 0.431 0.000
Z91.2 Personal history of poor personal hygiene
0.568 0.431 0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen
0.568 0.431 0.000
D12.3 Transverse colon
0.568 0.432 0.000
M13 Other arthritis
0.567 0.433 0.000
R56 Convulsions, not elsewhere classified
0.567 0.433 0.000
E03 Other hypothyroidism
0.566 0.434 0.000
Z80.9 Family history of malignant neoplasm, unspecified
0.565 0.435 0.000
Z80.8 Family history of malignant neoplasm of other organs or systems
0.565 0.435 0.000
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues
0.565 0.435 0.000
Z80.6 Family history of leukaemia
0.565 0.435 0.000
Z80.5 Family history of malignant neoplasm of urinary tract
0.565 0.435 0.000
Z80.4 Family history of malignant neoplasm of genital organs
0.565 0.435 0.000
Z80.3 Family history of malignant neoplasm of breast
0.565 0.435 0.000
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs
0.565 0.435 0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
0.565 0.435 0.000
C20 Malignant neoplasm of rectum
0.563 0.437 0.000
N32.9 Bladder disorder, unspecified
0.562 0.437 0.000
N32.4 Rupture of bladder, nontraumatic
0.562 0.437 0.000
N32.3 Diverticulum of bladder
0.562 0.437 0.000
N32.2 Vesical fistula, not elsewhere classified
0.562 0.437 0.000
N32.1 Vesicointestinal fistula
0.562 0.437 0.000
K57 Diverticular disease of intestine
0.562 0.438 0.000
C67 Malignant neoplasm of bladder
0.561 0.439 0.000
R55 Syncope and collapse
0.560 0.440 0.000
Z37 Outcome of delivery
0.559 0.441 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.558 0.442 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.558 0.442 0.000
Z50.8 Care involving use of rehabilitation procedures
0.558 0.442 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.558 0.442 0.000
Z50.6 Orthoptic training
0.558 0.442 0.000
Z50.5 Speech therapy
0.558 0.442 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.558 0.442 0.000
Z50.3 Drug rehabilitation
0.558 0.442 0.000
Z50.2 Alcohol rehabilitation
0.558 0.442 0.000
Z50.0 Cardiac rehabilitation
0.558 0.442 0.000
K50 Crohn's disease [regional enteritis]
0.557 0.443 0.000
L75 Apocrine sweat disorders
0.556 0.443 0.000
L74 Eccrine sweat disorders
0.556 0.443 0.000
L73 Other follicular disorders
0.556 0.443 0.000
L71 Rosacea
0.556 0.443 0.000
L70 Acne
0.556 0.443 0.000
L68 Hypertrichosis
0.556 0.443 0.000
L67 Hair colour and hair shaft abnormalities
0.556 0.443 0.000
L66 Cicatricial alopecia [scarring hair loss]
0.556 0.443 0.000
L65 Other nonscarring hair loss
0.556 0.443 0.000
L64 Androgenic alopecia
0.556 0.443 0.000
L63 Alopecia areata
0.556 0.443 0.000
L62 Nail disorders in diseases classified elsewhere
0.556 0.443 0.000
L60 Nail disorders
0.556 0.443 0.000
G90-G99 Other disorders of the nervous system
0.556 0.444 0.000
G70-G73 Diseases of myoneural junction and muscle
0.556 0.444 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.556 0.444 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.556 0.444 0.000
G30-G32 Other degenerative diseases of the nervous system
0.556 0.444 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.556 0.444 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.556 0.444 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.556 0.444 0.000
M20.5 Other deformities of toe(s) (acquired)
0.556 0.444 0.000
M20.3 Other deformity of hallux (acquired)
0.556 0.444 0.000
M20.0 Deformity of finger(s)
0.556 0.444 0.000
I51 Complications and ill-defined descriptions of heart disease
0.555 0.444 0.000
D05 Carcinoma in situ of breast
0.555 0.445 0.000
N81 Female genital prolapse
0.555 0.445 0.000
M17.1 Other primary gonarthrosis
0.554 0.446 0.000
D12.6 Colon, unspecified
0.553 0.447 0.000
E67 Other hyperalimentation
0.553 0.447 0.000
E68 Sequelae of hyperalimentation
0.553 0.447 0.000
E65 Localised adiposity
0.553 0.447 0.000
H80-H83 Diseases of inner ear
0.552 0.448 0.000
H65-H75 Diseases of middle ear and mastoid
0.552 0.448 0.000
H60-H62 Diseases of external ear
0.552 0.448 0.000
Z39 Postpartum care and examination
0.552 0.448 0.000
Z38 Liveborn infants according to place of birth
0.552 0.448 0.000
Z36 Antenatal screening
0.552 0.448 0.000
Z35 Supervision of high-risk pregnancy
0.552 0.448 0.000
Z34 Supervision of normal pregnancy
0.552 0.448 0.000
Z32 Pregnancy examination and test
0.552 0.448 0.000
Z31 Procreative management
0.552 0.448 0.000
Z33 Pregnant state, incidental
0.552 0.448 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.552 0.448 0.000
M85 Other disorders of bone density and structure
0.552 0.448 0.000
M84 Disorders of continuity of bone
0.552 0.448 0.000
M83 Adult osteomalacia
0.552 0.448 0.000
M82 Osteoporosis in diseases classified elsewhere
0.552 0.448 0.000
M80 Osteoporosis with pathological fracture
0.552 0.448 0.000
S00-S09 Injuries to the head
0.552 0.448 0.000
Z02 Examination and encounter for administrative purposes
0.551 0.448 0.000
N63 Unspecified lump in breast
0.551 0.448 0.000
M54 Dorsalgia
0.551 0.449 0.000
L40 Psoriasis
0.551 0.449 0.000
K82.9 Disease of gallbladder, unspecified
0.550 0.450 0.000
K82.4 Cholesterolosis of gallbladder
0.550 0.450 0.000
K82.3 Fistula of gallbladder
0.550 0.450 0.000
K82.2 Perforation of gallbladder
0.550 0.450 0.000
K82.1 Hydrops of gallbladder
0.550 0.450 0.000
K82.0 Obstruction of gallbladder
0.550 0.450 0.000
C43 Malignant melanoma of skin
0.550 0.450 0.000
R07 Pain in throat and chest
0.549 0.451 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.548 0.452 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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