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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs114383600
log Bayes Factor = 28.0206
Chromosome 5   position 58,193,856  (GRCh37) Explore rs114383600 on Ensembl!
Variant rs114383600 is part of Cluster X0152

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
Z86 Personal history of certain other diseases
0.999 0.001 0.000
Chapter VI Diseases of the nervous system
0.999 0.001 0.000
Chapter XIV Diseases of the genitourinary system
0.999 0.001 0.000
Z86.7 Personal history of diseases of the circulatory system
0.998 0.002 0.000
G40-G47 Episodic and paroxysmal disorders
0.997 0.003 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.996 0.004 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.996 0.004 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.994 0.006 0.000
Z92 Personal history of medical treatment
0.993 0.007 0.000
G47 Sleep disorders
0.991 0.009 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.989 0.011 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.988 0.012 0.000
N17-N19 Renal failure
0.987 0.013 0.000
R30-R39 Symptoms and signs involving the urinary system
0.986 0.014 0.000
E70-E90 Metabolic disorders
0.986 0.014 0.000
G47.3 Sleep apnoea
0.983 0.017 0.000
Chapter II Neoplasms
0.983 0.017 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.981 0.019 0.000
D60-D64 Aplastic and other anaemias
0.978 0.022 0.000
Chapter VII Diseases of the eye and adnexa
0.977 0.023 0.000
Chapter X Diseases of the respiratory system
0.976 0.024 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.971 0.029 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.970 0.030 0.000
R06 Abnormalities of breathing
0.969 0.031 0.000
K90-K93 Other diseases of the digestive system
0.968 0.032 0.000
K40-K46 Hernia
0.965 0.035 0.000
D64 Other anaemias
0.964 0.036 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.960 0.040 0.000
R79 Other abnormal findings of blood chemistry
0.959 0.041 0.000
R31 Unspecified haematuria
0.955 0.045 0.000
K44 Diaphragmatic hernia
0.955 0.045 0.000
D64.9 Anaemia, unspecified
0.955 0.045 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.952 0.048 0.000
J30-J39 Other diseases of upper respiratory tract
0.952 0.048 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.952 0.048 0.000
K44.9 Diaphragmatic hernia without obstruction or gangrene
0.949 0.051 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.949 0.051 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.944 0.056 0.000
N40-N51 Diseases of male genital organs
0.944 0.056 0.000
N17 Acute renal failure
0.941 0.059 0.000
K92 Other diseases of digestive system
0.940 0.060 0.000
I60-I69 Cerebrovascular diseases
0.935 0.065 0.000
J34 Other disorders of nose and nasal sinuses
0.935 0.065 0.000
S00-S09 Injuries to the head
0.934 0.066 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.930 0.070 0.000
G40 Epilepsy
0.928 0.072 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.924 0.076 0.000
E10-E14 Diabetes mellitus
0.922 0.078 0.000
R06.5 Mouth breathing
0.921 0.079 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.921 0.079 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.919 0.081 0.000
Z46 Fitting and adjustment of other devices
0.918 0.082 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.917 0.083 0.000
Z53.0 Procedure not carried out because of contraindication
0.914 0.086 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.913 0.087 0.000
I71 Aortic aneurysm and dissection
0.913 0.087 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.911 0.089 0.000
J34.2 Deviated nasal septum
0.910 0.090 0.000
N17.9 Acute renal failure, unspecified
0.909 0.091 0.000
N30-N39 Other diseases of urinary system
0.908 0.092 0.000
E87.6 Hypokalaemia
0.908 0.092 0.000
Z86.1 Personal history of infectious and parasitic diseases
0.907 0.093 0.000
Chapter I Certain infectious and parasitic diseases
0.906 0.094 0.000
H53-H54 Visual disturbances and blindness
0.903 0.097 0.000
N18 Chronic renal failure
0.895 0.105 0.000
R00 Abnormalities of heart beat
0.895 0.105 0.000
K08 Other disorders of teeth and supporting structures
0.888 0.112 0.000
T66-T78 Other and unspecified effects of external causes
0.887 0.113 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.886 0.114 0.000
C64-C68 Malignant neoplasms of urinary tract
0.885 0.115 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.885 0.115 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.884 0.116 0.000
I30-I52 Other forms of heart disease
0.882 0.118 0.000
K92.1 Melaena
0.878 0.122 0.000
R35 Polyuria
0.878 0.122 0.000
Chapter V Mental and behavioural disorders
0.876 0.124 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.875 0.125 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.875 0.125 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.875 0.125 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.873 0.127 0.000
K20 Oesophagitis
0.872 0.128 0.000
R50-R69 General symptoms and signs
0.869 0.131 0.000
N48 Other disorders of penis
0.868 0.132 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.861 0.139 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.859 0.141 0.000
E86 Volume depletion
0.859 0.141 0.000
C78.0 Secondary malignant neoplasm of lung
0.857 0.143 0.000
K55-K64 Other diseases of intestines
0.852 0.148 0.000
R06.0 Dyspnoea
0.851 0.149 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.848 0.152 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.846 0.154 0.000
R03.1 Nonspecific low blood-pressure reading
0.845 0.155 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.844 0.156 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.842 0.158 0.000
R00.1 Bradycardia, unspecified
0.842 0.158 0.000
C15-C26 Malignant neoplasms of digestive organs
0.841 0.159 0.000
B35-B49 Mycoses
0.841 0.159 0.000
K60 Fissure and fistula of anal and rectal regions
0.839 0.161 0.000
J34.3 Hypertrophy of nasal turbinates
0.839 0.161 0.000
Z88.2 Personal history of allergy to sulphonamides
0.838 0.162 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.837 0.162 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.837 0.163 0.000
Z60 Problems related to social environment
0.835 0.164 0.000
S09 Other and unspecified injuries of head
0.835 0.165 0.000
Z89 Acquired absence of limb
0.834 0.166 0.000
S01 Open wound of head
0.832 0.168 0.000
G40.9 Epilepsy, unspecified
0.832 0.168 0.000
H10-H13 Disorders of conjunctiva
0.829 0.171 0.000
Z46.6 Fitting and adjustment of urinary device
0.829 0.171 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.828 0.171 0.000
K14 Diseases of tongue
0.827 0.173 0.000
T39.0 Salicylates
0.826 0.174 0.000
N19 Unspecified renal failure
0.825 0.175 0.000
J95-J99 Other diseases of the respiratory system
0.825 0.175 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.825 0.175 0.000
K65-K67 Diseases of peritoneum
0.821 0.179 0.000
I61 Intracerebral haemorrhage
0.820 0.180 0.000
N35 Urethral stricture
0.820 0.180 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.818 0.181 0.000
N50 Other disorders of male genital organs
0.817 0.183 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.814 0.186 0.000
K21 Gastro-oesophageal reflux disease
0.814 0.186 0.000
J35 Chronic diseases of tonsils and adenoids
0.813 0.187 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.809 0.191 0.000
I05-I09 Chronic rheumatic heart diseases
0.808 0.191 0.000
Z97 Presence of other devices
0.808 0.192 0.000
Z46.5 Fitting and adjustment of ileostomy and other intestinal appliances
0.808 0.192 0.000
K92.0 Haematemesis
0.807 0.193 0.000
T78 Adverse effects, not elsewhere classified
0.807 0.193 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.807 0.193 0.000
J36 Peritonsillar abscess
0.806 0.194 0.000
E87.2 Acidosis
0.804 0.196 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.804 0.196 0.000
G35 Multiple sclerosis
0.804 0.196 0.000
N60-N64 Disorders of breast
0.803 0.197 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.802 0.197 0.000
E00-E07 Disorders of thyroid gland
0.802 0.198 0.000
K50-K52 Noninfective enteritis and colitis
0.800 0.200 0.000
S80-S89 Injuries to the knee and lower leg
0.800 0.200 0.000
Chapter VIII Diseases of the ear and mastoid process
0.799 0.200 0.000
K08.8 Other specified disorders of teeth and supporting structures
0.797 0.203 0.000
Z45 Adjustment and management of implanted device
0.797 0.203 0.000
N39 Other disorders of urinary system
0.796 0.204 0.000
Z86.5 Personal history of other mental and behavioural disorders
0.795 0.205 0.000
H53 Visual disturbances
0.794 0.206 0.000
B37 Candidiasis
0.794 0.206 0.000
D61 Other aplastic anaemias
0.794 0.206 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.793 0.207 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.793 0.207 0.000
K60.3 Anal fistula
0.792 0.208 0.000
I67 Other cerebrovascular diseases
0.791 0.209 0.000
K60.2 Anal fissure, unspecified
0.791 0.209 0.000
R63 Symptoms and signs concerning food and fluid intake
0.790 0.210 0.000
C18 Malignant neoplasm of colon
0.787 0.213 0.000
S70-S79 Injuries to the hip and thigh
0.786 0.214 0.000
C51-C58 Malignant neoplasms of female genital organs
0.785 0.215 0.000
T51 Toxic effect of alcohol
0.785 0.215 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.784 0.216 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.783 0.217 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.782 0.218 0.000
C67 Malignant neoplasm of bladder
0.781 0.219 0.000
H54 Blindness and low vision
0.781 0.219 0.000
Chapter XX External causes of morbidity and mortality
0.780 0.220 0.000
N40 Hyperplasia of prostate
0.780 0.220 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.779 0.221 0.000
Z48 Other surgical follow-up care
0.779 0.221 0.000
K02 Dental caries
0.778 0.222 0.000
E10 Insulin-dependent diabetes mellitus
0.778 0.222 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.777 0.223 0.000
R02 Gangrene, not elsewhere classified
0.777 0.223 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.777 0.223 0.000
Z94 Transplanted organ and tissue status
0.776 0.224 0.000
R05 Cough
0.774 0.226 0.000
R61 Hyperhidrosis
0.774 0.226 0.000
Z60.2 Living alone
0.772 0.228 0.000
K04 Diseases of pulp and periapical tissues
0.771 0.229 0.000
S60-S69 Injuries to the wrist and hand
0.771 0.229 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.771 0.229 0.000
Z92.0 Personal history of contraception
0.769 0.231 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.768 0.232 0.000
E11 Non-insulin-dependent diabetes mellitus
0.767 0.233 0.000
K92.2 Gastro-intestinal haemorrhage, unspecified
0.767 0.233 0.000
N10-N16 Renal tubulo-interstitial diseases
0.767 0.233 0.000
S20-S29 Injuries to the thorax
0.767 0.233 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.765 0.235 0.000
S09.9 Unspecified injury of head
0.765 0.235 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.764 0.236 0.000
K07 Dentofacial anomalies [including malocclusion]
0.762 0.238 0.000
Z54 Convalescence
0.761 0.239 0.000
E14 Unspecified diabetes mellitus
0.760 0.240 0.000
G20-G26 Extrapyramidal and movement disorders
0.758 0.242 0.000
R32 Unspecified urinary incontinence
0.758 0.242 0.000
T39.1 4-Aminophenol derivatives
0.758 0.242 0.000
T43.2 Other and unspecified antidepressants
0.757 0.243 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.757 0.243 0.000
N42 Other disorders of prostate
0.756 0.244 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.756 0.244 0.000
N35.9 Urethral stricture, unspecified
0.756 0.244 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.756 0.244 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.755 0.245 0.000
S90-S99 Injuries to the ankle and foot
0.754 0.246 0.000
G43 Migraine
0.753 0.247 0.000
H02 Other disorders of eyelid
0.753 0.247 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.752 0.248 0.000
R73 Elevated blood glucose level
0.750 0.250 0.000
H55-H59 Other disorders of eye and adnexa
0.748 0.252 0.000
E88 Other metabolic disorders
0.748 0.252 0.000
C77.3 Axillary and upper limb lymph nodes
0.748 0.252 0.000
K12 Stomatitis and related lesions
0.747 0.252 0.000
N18.3 Chronic kidney disease, stage 3
0.747 0.253 0.000
I44 Atrioventricular and left bundle-branch block
0.746 0.254 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.746 0.254 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.746 0.254 0.000
Z86.4 Personal history of psychoactive substance abuse
0.745 0.255 0.000
C79 Secondary malignant neoplasm of other sites
0.744 0.256 0.000
Z83 Family history of other specific disorders
0.744 0.256 0.000
K70-K77 Diseases of liver
0.744 0.256 0.000
I46 Cardiac arrest
0.744 0.256 0.000
Z93 Artificial opening status
0.742 0.258 0.000
I95 Hypotension
0.742 0.258 0.000
I63 Cerebral infarction
0.741 0.259 0.000
K10 Other diseases of jaws
0.740 0.260 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.740 0.260 0.000
R33 Retention of urine
0.740 0.260 0.000
G30-G32 Other degenerative diseases of the nervous system
0.740 0.260 0.000
G44 Other headache syndromes
0.740 0.260 0.000
E83 Disorders of mineral metabolism
0.740 0.260 0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension
0.739 0.261 0.000
E20-E35 Disorders of other endocrine glands
0.739 0.261 0.000
I62 Other nontraumatic intracranial haemorrhage
0.737 0.263 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.737 0.263 0.000
D80-D89 Certain disorders involving the immune mechanism
0.737 0.263 0.000
Z90.7 Acquired absence of genital organ(s)
0.737 0.263 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.737 0.263 0.000
C18.9 Colon, unspecified
0.735 0.265 0.000
I73 Other peripheral vascular diseases
0.735 0.265 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.734 0.266 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.733 0.267 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.732 0.268 0.000
Z57 Occupational exposure to risk-factors
0.731 0.269 0.000
I72 Other aneurysm
0.731 0.269 0.000
T78.4 Allergy, unspecified
0.731 0.269 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.731 0.269 0.000
G90-G99 Other disorders of the nervous system
0.731 0.269 0.000
J30 Vasomotor and allergic rhinitis
0.729 0.271 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.728 0.271 0.000
N18.4 Chronic kidney disease, stage 4
0.728 0.272 0.000
N60 Benign mammary dysplasia
0.727 0.273 0.000
R56 Convulsions, not elsewhere classified
0.724 0.276 0.000
I69 Sequelae of cerebrovascular disease
0.724 0.276 0.000
H43-H45 Disorders of vitreous body and globe
0.724 0.276 0.000
I47 Paroxysmal tachycardia
0.723 0.277 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.723 0.277 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.723 0.277 0.000
R63.4 Abnormal weight loss
0.723 0.277 0.000
K08.3 Retained dental root
0.723 0.277 0.000
J60-J70 Lung diseases due to external agents
0.723 0.277 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.722 0.278 0.000
S01.8 Open wound of other parts of head
0.721 0.279 0.000
T51.0 Ethanol
0.721 0.279 0.000
R39 Other symptoms and signs involving the urinary system
0.720 0.280 0.000
Z95.2 Presence of prosthetic heart valve
0.720 0.280 0.000
I85 Oesophageal varices
0.720 0.280 0.000
A00-A09 Intestinal infectious diseases
0.720 0.280 0.000
K35-K38 Diseases of appendix
0.719 0.281 0.000
R60 Oedema, not elsewhere classified
0.718 0.282 0.000
N48.6 Balanitis xerotica obliterans
0.718 0.282 0.000
E11.9 Without complications
0.718 0.282 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.718 0.282 0.000
J98 Other respiratory disorders
0.718 0.282 0.000
Chapter XXII Codes for special purposes
0.717 0.282 0.000
Z92.3 Personal history of irradiation
0.717 0.283 0.000
H50 Other strabismus
0.717 0.283 0.000
Z95.4 Presence of other heart-valve replacement
0.717 0.283 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
Z81 Family history of mental and behavioural disorders
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.716 0.283 0.000
I00-I02 Acute rheumatic fever
0.716 0.283 0.000
G70-G73 Diseases of myoneural junction and muscle
0.716 0.284 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.716 0.284 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.716 0.284 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.716 0.284 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.715 0.285 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.715 0.285 0.000
G41 Status epilepticus
0.715 0.285 0.000
N50.1 Vascular disorders of male genital organs
0.715 0.285 0.000
E40-E46 Malnutrition
0.714 0.286 0.000
E87.7 Fluid overload
0.714 0.286 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.713 0.287 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.712 0.288 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.712 0.288 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.712 0.288 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.712 0.288 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.712 0.288 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.712 0.288 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.712 0.288 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.712 0.288 0.000
T36 Poisoning by systemic antibiotics
0.712 0.288 0.000
E04 Other non-toxic goitre
0.712 0.288 0.000
Z92.9 Personal history of medical treatment, unspecified
0.712 0.288 0.000
Z92.8 Personal history of other medical treatment
0.712 0.288 0.000
Z92.5 Personal history of rehabilitation measures
0.712 0.288 0.000
R51 Headache
0.711 0.289 0.000
G47.8 Other sleep disorders
0.710 0.290 0.000
G47.4 Narcolepsy and cataplexy
0.710 0.290 0.000
G47.2 Disorders of the sleep-wake schedule
0.710 0.290 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.710 0.290 0.000
D55-D59 Haemolytic anaemias
0.709 0.291 0.000
Z47 Other orthopaedic follow-up care
0.708 0.292 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.708 0.292 0.000
Z63 Other problems related to primary support group, including family circumstances
0.708 0.292 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.707 0.292 0.000
R06.8 Other and unspecified abnormalities of breathing
0.707 0.293 0.000
R36 Urethral discharge
0.707 0.293 0.000
R34 Anuria and oliguria
0.707 0.293 0.000
E85 Amyloidosis
0.707 0.293 0.000
E84 Cystic fibrosis
0.707 0.293 0.000
E79 Disorders of purine and pyrimidine metabolism
0.707 0.293 0.000
E77 Disorders of glycoprotein metabolism
0.707 0.293 0.000
E76 Disorders of glycosaminoglycan metabolism
0.707 0.293 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.707 0.293 0.000
E74 Other disorders of carbohydrate metabolism
0.707 0.293 0.000
E73 Lactose intolerance
0.707 0.293 0.000
E72 Other disorders of amino-acid metabolism
0.707 0.293 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.707 0.293 0.000
E70 Disorders of aromatic amino-acid metabolism
0.707 0.293 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.707 0.293 0.000
J00-J06 Acute upper respiratory infections
0.707 0.293 0.000
R61.9 Hyperhidrosis, unspecified
0.706 0.294 0.000
K65 Peritonitis
0.705 0.295 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.705 0.295 0.000
K90 Intestinal malabsorption
0.705 0.295 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.704 0.295 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.704 0.295 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.704 0.295 0.000
D00-D09 In situ neoplasms
0.704 0.296 0.000
I27 Other pulmonary heart diseases
0.704 0.296 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.703 0.297 0.000
R77 Other abnormalities of plasma proteins
0.703 0.297 0.000
R76 Other abnormal immunological findings in serum
0.703 0.297 0.000
R74 Abnormal serum enzyme levels
0.703 0.297 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.703 0.297 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.703 0.297 0.000
R71 Abnormality of red blood cells
0.703 0.297 0.000
R07 Pain in throat and chest
0.703 0.297 0.000
S01.5 Open wound of lip and oral cavity
0.703 0.297 0.000
R23 Other skin changes
0.702 0.298 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.702 0.298 0.000
I10-I15 Hypertensive diseases
0.702 0.298 0.000
S50-S59 Injuries to the elbow and forearm
0.702 0.298 0.000
E10.9 Without complications
0.701 0.299 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.701 0.299 0.000
D62 Acute posthaemorrhagic anaemia
0.701 0.299 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.700 0.300 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.700 0.300 0.000
J35.1 Hypertrophy of tonsils
0.700 0.300 0.000
Z90.2 Acquired absence of lung [part of]
0.700 0.300 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.699 0.301 0.000
I20-I25 Ischaemic heart diseases
0.699 0.301 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.699 0.301 0.000
K26 Duodenal ulcer
0.699 0.301 0.000
Z40 Prophylactic surgery
0.699 0.301 0.000
K14.8 Other diseases of tongue
0.699 0.301 0.000
N18.5 Chronic kidney disease, stage 5
0.699 0.301 0.000
I33 Acute and subacute endocarditis
0.697 0.303 0.000
Z52 Donors of organs and tissues
0.696 0.303 0.000
Z49 Care involving dialysis
0.696 0.303 0.000
Z44 Fitting and adjustment of external prosthetic device
0.696 0.303 0.000
K29 Gastritis and duodenitis
0.696 0.304 0.000
N48.8 Other specified disorders of penis
0.696 0.304 0.000
K50 Crohn's disease [regional enteritis]
0.696 0.304 0.000
K11 Diseases of salivary glands
0.696 0.304 0.000
K09 Cysts of oral region, not elsewhere classified
0.696 0.304 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.696 0.304 0.000
K03 Other diseases of hard tissues of teeth
0.696 0.304 0.000
K00 Disorders of tooth development and eruption
0.696 0.304 0.000
K61 Abscess of anal and rectal regions
0.696 0.304 0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.695 0.305 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.694 0.305 0.000
R06.7 Sneezing
0.694 0.305 0.000
R06.6 Hiccough
0.694 0.305 0.000
R06.4 Hyperventilation
0.694 0.305 0.000
R06.3 Periodic breathing
0.694 0.305 0.000
R06.2 Wheezing
0.694 0.305 0.000
R06.1 Stridor
0.694 0.305 0.000
C77.0 Lymph nodes of head, face and neck
0.694 0.306 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.694 0.306 0.000
N48.1 Balanoposthitis
0.693 0.307 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.693 0.307 0.000
F30-F39 Mood [affective] disorders
0.693 0.307 0.000
J40-J47 Chronic lower respiratory diseases
0.693 0.307 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.692 0.308 0.000
K41 Femoral hernia
0.692 0.308 0.000
N00-N08 Glomerular diseases
0.692 0.308 0.000
K46 Unspecified abdominal hernia
0.691 0.308 0.000
K45 Other abdominal hernia
0.691 0.308 0.000
D64.8 Other specified anaemias
0.691 0.308 0.000
D64.4 Congenital dyserythropoietic anaemia
0.691 0.308 0.000
D64.3 Other sideroblastic anaemias
0.691 0.308 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.691 0.308 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.691 0.308 0.000
D64.0 Hereditary sideroblastic anaemia
0.691 0.308 0.000
N48.0 Leukoplakia of penis
0.691 0.309 0.000
I80 Phlebitis and thrombophlebitis
0.691 0.309 0.000
I42 Cardiomyopathy
0.691 0.309 0.000
N72 Inflammatory disease of cervix uteri
0.691 0.309 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.689 0.311 0.000
C77.5 Intrapelvic lymph nodes
0.689 0.311 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.689 0.311 0.000
C80 Malignant neoplasm without specification of site
0.688 0.312 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.688 0.312 0.000
K21.9 Gastro-oesophageal reflux disease without oesophagitis
0.688 0.312 0.000
J90-J94 Other diseases of pleura
0.688 0.312 0.000
R79.9 Abnormal finding of blood chemistry, unspecified
0.688 0.312 0.000
R79.0 Abnormal level of blood mineral
0.688 0.312 0.000
N32 Other disorders of bladder
0.687 0.313 0.000
I60 Subarachnoid haemorrhage
0.687 0.313 0.000
H11 Other disorders of conjunctiva
0.686 0.314 0.000
K44.1 Diaphragmatic hernia with gangrene
0.685 0.315 0.000
K44.0 Diaphragmatic hernia with obstruction, without gangrene
0.685 0.315 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.685 0.315 0.000
B37.0 Candidal stomatitis
0.684 0.316 0.000
N25-N29 Other disorders of kidney and ureter
0.683 0.317 0.000
H30-H36 Disorders of choroid and retina
0.683 0.317 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.683 0.317 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.683 0.317 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.683 0.317 0.000
J37 Chronic laryngitis and laryngotracheitis
0.682 0.318 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.682 0.318 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.682 0.318 0.000
I70 Atherosclerosis
0.682 0.318 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.682 0.318 0.000
C77.4 Inguinal and lower limb lymph nodes
0.682 0.318 0.000
T42.4 Benzodiazepines
0.682 0.318 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.680 0.320 0.000
E87.4 Mixed disorder of acid-base balance
0.680 0.320 0.000
E87.3 Alkalosis
0.680 0.320 0.000
E87.0 Hyperosmolality and hypernatraemia
0.680 0.320 0.000
B15-B19 Viral hepatitis
0.680 0.320 0.000
N18.9 Chronic renal failure, unspecified
0.679 0.321 0.000
N99-N99 Other disorders of the genitourinary system
0.678 0.321 0.000
N70 Salpingitis and oophoritis
0.678 0.322 0.000
Z89.5 Acquired absence of leg at or below knee
0.678 0.322 0.000
S40-S49 Injuries to the shoulder and upper arm
0.677 0.322 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.677 0.323 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.677 0.323 0.000
N46 Male infertility
0.677 0.323 0.000
N44 Torsion of testis
0.677 0.323 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.675 0.325 0.000
N17.8 Other acute renal failure
0.675 0.325 0.000
N17.2 Acute renal failure with medullary necrosis
0.675 0.325 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.675 0.325 0.000
N17.0 Acute renal failure with tubular necrosis
0.675 0.325 0.000
N36 Other disorders of urethra
0.674 0.326 0.000
K25 Gastric ulcer
0.674 0.326 0.000
K92.9 Disease of digestive system, unspecified
0.674 0.326 0.000
K92.8 Other specified diseases of digestive system
0.674 0.326 0.000
N76 Other inflammation of vagina and vulva
0.674 0.326 0.000
K55 Vascular disorders of intestine
0.673 0.327 0.000
I78 Diseases of capillaries
0.673 0.327 0.000
C77.9 Lymph node, unspecified
0.673 0.327 0.000
E50-E64 Other nutritional deficiencies
0.672 0.328 0.000
I86 Varicose veins of other sites
0.672 0.328 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.672 0.328 0.000
I08 Multiple valve diseases
0.671 0.329 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.670 0.330 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.670 0.330 0.000
R01 Cardiac murmurs and other cardiac sounds
0.670 0.330 0.000
J34.1 Cyst and mucocele of nose and nasal sinus
0.670 0.330 0.000
J34.0 Abscess, furuncle and carbuncle of nose
0.670 0.330 0.000
S08 Traumatic amputation of part of head
0.669 0.330 0.000
S07 Crushing injury of head
0.669 0.330 0.000
S06 Intracranial injury
0.669 0.330 0.000
S05 Injury of eye and orbit
0.669 0.330 0.000
S04 Injury of cranial nerves
0.669 0.330 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.669 0.330 0.000
K28 Gastrojejunal ulcer
0.667 0.333 0.000
K27 Peptic ulcer, site unspecified
0.667 0.333 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.667 0.333 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.667 0.333 0.000
N41 Inflammatory diseases of prostate
0.667 0.333 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.666 0.334 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.666 0.334 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.666 0.334 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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