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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs114450019
log Bayes Factor = 13.3669
Chromosome 1   position 185,420,876  (GRCh37) Explore rs114450019 on Ensembl!
Variant rs114450019 is part of Cluster X0140

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E70-E90 Metabolic disorders
0.999 0.001 0.000
I30-I52 Other forms of heart disease
0.997 0.003 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.996 0.004 0.000
I10-I15 Hypertensive diseases
0.993 0.007 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.988 0.012 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.986 0.014 0.000
N18 Chronic renal failure
0.982 0.018 0.000
N17-N19 Renal failure
0.982 0.018 0.000
I44 Atrioventricular and left bundle-branch block
0.981 0.019 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.980 0.020 0.000
Chapter XIV Diseases of the genitourinary system
0.980 0.020 0.000
I05-I09 Chronic rheumatic heart diseases
0.976 0.024 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.972 0.028 0.000
Chapter II Neoplasms
0.971 0.029 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.969 0.031 0.000
N18.9 Chronic renal failure, unspecified
0.966 0.034 0.000
I34 Nonrheumatic mitral valve disorders
0.965 0.035 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.964 0.036 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.960 0.040 0.000
C44 Other malignant neoplasms of skin
0.958 0.042 0.000
I12 Hypertensive renal disease
0.957 0.043 0.000
I44.7 Left bundle-branch block, unspecified
0.956 0.044 0.000
Chapter VII Diseases of the eye and adnexa
0.953 0.047 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.948 0.052 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.947 0.053 0.000
I10 Essential (primary) hypertension
0.946 0.054 0.000
T81 Complications of procedures, not elsewhere classified
0.943 0.057 0.000
I12.0 Hypertensive renal disease with renal failure
0.936 0.064 0.000
N00-N08 Glomerular diseases
0.934 0.066 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.932 0.068 0.000
W00-W19 Falls
0.930 0.070 0.000
I34.0 Mitral (valve) insufficiency
0.930 0.070 0.000
E78.0 Pure hypercholesterolaemia
0.928 0.072 0.000
I08 Multiple valve diseases
0.924 0.076 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.921 0.079 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.920 0.080 0.000
S80-S89 Injuries to the knee and lower leg
0.913 0.087 0.000
S60-S69 Injuries to the wrist and hand
0.910 0.090 0.000
N18.3 Chronic kidney disease, stage 3
0.907 0.093 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.904 0.096 0.000
Chapter X Diseases of the respiratory system
0.903 0.097 0.000
H53-H54 Visual disturbances and blindness
0.902 0.098 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.902 0.098 0.000
E86 Volume depletion
0.898 0.102 0.000
T39.1 4-Aminophenol derivatives
0.897 0.103 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.891 0.109 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.890 0.110 0.000
C44.6 Skin of upper limb, including shoulder
0.889 0.111 0.000
Chapter VIII Diseases of the ear and mastoid process
0.886 0.114 0.000
Y43 Primarily systemic agents
0.877 0.123 0.000
N18.5 Chronic kidney disease, stage 5
0.876 0.124 0.000
I05 Rheumatic mitral valve diseases
0.868 0.132 0.000
E20-E35 Disorders of other endocrine glands
0.868 0.132 0.000
I44.1 Atrioventricular block, second degree
0.867 0.133 0.000
C44.7 Skin of lower limb, including hip
0.866 0.134 0.000
Y83.4 Other reconstructive surgery
0.865 0.135 0.000
I20-I25 Ischaemic heart diseases
0.862 0.138 0.000
E87.5 Hyperkalaemia
0.858 0.142 0.000
N17 Acute renal failure
0.856 0.144 0.000
I47 Paroxysmal tachycardia
0.850 0.149 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.850 0.150 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.848 0.152 0.000
H55-H59 Other disorders of eye and adnexa
0.847 0.153 0.000
I50 Heart failure
0.845 0.155 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.843 0.157 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.841 0.159 0.000
C44.4 Skin of scalp and neck
0.837 0.163 0.000
E10-E14 Diabetes mellitus
0.836 0.164 0.000
E89.0 Postprocedural hypothyroidism
0.832 0.168 0.000
H54 Blindness and low vision
0.831 0.169 0.000
Y83.6 Removal of other organ (partial) (total)
0.828 0.172 0.000
C34 Malignant neoplasm of bronchus and lung
0.827 0.173 0.000
C44.3 Skin of other and unspecified parts of face
0.825 0.175 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.823 0.177 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.823 0.177 0.000
I08.0 Disorders of both mitral and aortic valves
0.821 0.179 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.820 0.180 0.000
S40-S49 Injuries to the shoulder and upper arm
0.818 0.182 0.000
J95-J99 Other diseases of the respiratory system
0.817 0.183 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.815 0.185 0.000
N03 Chronic nephritic syndrome
0.808 0.192 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.808 0.192 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.808 0.192 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.805 0.195 0.000
N18.4 Chronic kidney disease, stage 4
0.802 0.197 0.000
S90-S99 Injuries to the ankle and foot
0.802 0.198 0.000
C44.5 Skin of trunk
0.801 0.199 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.799 0.201 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.799 0.201 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.794 0.206 0.000
I47.1 Supraventricular tachycardia
0.794 0.206 0.000
Y83.9 Surgical procedure, unspecified
0.794 0.206 0.000
J90-J94 Other diseases of pleura
0.793 0.207 0.000
I34.1 Mitral (valve) prolapse
0.792 0.208 0.000
I83 Varicose veins of lower extremities
0.791 0.209 0.000
W19 Unspecified fall
0.791 0.209 0.000
S70-S79 Injuries to the hip and thigh
0.790 0.210 0.000
E87.6 Hypokalaemia
0.790 0.210 0.000
S64 Injury of nerves at wrist and hand level
0.789 0.211 0.000
C15-C26 Malignant neoplasms of digestive organs
0.787 0.213 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.785 0.215 0.000
Y83.3 Surgical operation with formation of external stoma
0.783 0.217 0.000
E87.7 Fluid overload
0.783 0.217 0.000
E88 Other metabolic disorders
0.782 0.218 0.000
S80 Superficial injury of lower leg
0.781 0.219 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.781 0.219 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.781 0.219 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.781 0.219 0.000
T79-T79 Certain early complications of trauma
0.781 0.219 0.000
E00-E07 Disorders of thyroid gland
0.780 0.220 0.000
I37 Pulmonary valve disorders
0.777 0.223 0.000
N02 Recurrent and persistent haematuria
0.777 0.223 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.776 0.224 0.000
Y57 Other and unspecified drugs and medicaments
0.776 0.224 0.000
I11 Hypertensive heart disease
0.773 0.227 0.000
H53 Visual disturbances
0.773 0.227 0.000
N19 Unspecified renal failure
0.773 0.227 0.000
C44.0 Skin of lip
0.772 0.228 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.771 0.229 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.770 0.230 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.768 0.232 0.000
E40-E46 Malnutrition
0.767 0.233 0.000
S50-S59 Injuries to the elbow and forearm
0.767 0.233 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.766 0.234 0.000
N17.9 Acute renal failure, unspecified
0.766 0.234 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.763 0.237 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.762 0.238 0.000
Y43.1 Antineoplastic antimetabolites
0.761 0.239 0.000
W13 Fall from, out of or through building or structure
0.761 0.239 0.000
H54.9 Unspecified visual impairment (binocular)
0.759 0.241 0.000
N18.2 Chronic kidney disease, stage 2
0.757 0.243 0.000
I05.0 Mitral stenosis
0.755 0.245 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.755 0.245 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.754 0.246 0.000
N18.0 End-stage renal disease
0.753 0.247 0.000
Y83.5 Amputation of limb(s)
0.752 0.248 0.000
T85.2 Mechanical complication of intraocular lens
0.751 0.249 0.000
I07 Rheumatic tricuspid valve diseases
0.750 0.250 0.000
T81.9 Unspecified complication of procedure
0.750 0.250 0.000
W08 Fall involving other furniture
0.749 0.251 0.000
S62 Fracture at wrist and hand level
0.747 0.253 0.000
E78.5 Hyperlipidaemia, unspecified
0.747 0.253 0.000
C15 Malignant neoplasm of oesophagus
0.746 0.254 0.000
C79 Secondary malignant neoplasm of other sites
0.746 0.254 0.000
Y83.0 Surgical operation with transplant of whole organ
0.744 0.256 0.000
C32 Malignant neoplasm of larynx
0.743 0.257 0.000
C43 Malignant melanoma of skin
0.742 0.258 0.000
Y52 Agents primarily affecting the cardiovascular system
0.740 0.260 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.739 0.260 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.739 0.261 0.000
C34.3 Lower lobe, bronchus or lung
0.739 0.261 0.000
Chapter XXII Codes for special purposes
0.739 0.261 0.000
I50.0 Congestive heart failure
0.738 0.262 0.000
H80-H83 Diseases of inner ear
0.738 0.262 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.737 0.263 0.000
J00-J06 Acute upper respiratory infections
0.737 0.263 0.000
Y44 Agents primarily affecting blood constituents
0.737 0.263 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.736 0.263 0.000
N04 Nephrotic syndrome
0.736 0.264 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.736 0.264 0.000
Y45.0 Opioids and related analgesics
0.734 0.266 0.000
W19.9 Unspecified place
0.732 0.268 0.000
H43-H45 Disorders of vitreous body and globe
0.730 0.270 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.730 0.270 0.000
I31 Other diseases of pericardium
0.729 0.271 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.729 0.271 0.000
S81 Open wound of lower leg
0.728 0.272 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.728 0.272 0.000
Y95 Nosocomial condition
0.727 0.273 0.000
H40-H42 Glaucoma
0.723 0.277 0.000
J98 Other respiratory disorders
0.723 0.277 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.722 0.278 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.722 0.278 0.000
H65-H75 Diseases of middle ear and mastoid
0.721 0.279 0.000
I35 Nonrheumatic aortic valve disorders
0.719 0.281 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.719 0.281 0.000
N03.9 Unspecified
0.718 0.282 0.000
W07 Fall involving chair
0.718 0.282 0.000
Y40 Systemic antibiotics
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.717 0.283 0.000
Y10-Y34 Event of undetermined intent
0.717 0.283 0.000
Y00-Y09 Assault
0.717 0.283 0.000
X85-X99 Assault
0.717 0.283 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.717 0.283 0.000
X50-X57 Overexertion, travel and privation
0.717 0.283 0.000
X30-X39 Exposure to forces of nature
0.717 0.283 0.000
X20-X29 Contact with venomous animals and plants
0.717 0.283 0.000
X10-X19 Contact with heat and hot substances
0.717 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.717 0.283 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.717 0.283 0.000
W75-W84 Other accidental threats to breathing
0.717 0.283 0.000
W65-W74 Accidental drowning and submersion
0.717 0.283 0.000
W50-W64 Exposure to animate mechanical forces
0.717 0.283 0.000
V98-V99 Other and unspecified transport accidents
0.717 0.283 0.000
V95-V97 Air and space transport accidents
0.717 0.283 0.000
V90-V94 Water transport accidents
0.717 0.283 0.000
V80-V89 Other land transport accidents
0.717 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.717 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.717 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.717 0.283 0.000
V40-V49 Car occupant injured in transport accident
0.717 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.717 0.283 0.000
V01-V09 Pedestrian injured in transport accident
0.717 0.283 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.717 0.283 0.000
E85 Amyloidosis
0.716 0.284 0.000
E84 Cystic fibrosis
0.716 0.284 0.000
E79 Disorders of purine and pyrimidine metabolism
0.716 0.284 0.000
E77 Disorders of glycoprotein metabolism
0.716 0.284 0.000
E76 Disorders of glycosaminoglycan metabolism
0.716 0.284 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.716 0.284 0.000
E74 Other disorders of carbohydrate metabolism
0.716 0.284 0.000
E73 Lactose intolerance
0.716 0.284 0.000
E72 Other disorders of amino-acid metabolism
0.716 0.284 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.716 0.284 0.000
E70 Disorders of aromatic amino-acid metabolism
0.716 0.284 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.716 0.284 0.000
D00-D09 In situ neoplasms
0.716 0.284 0.000
I50.9 Heart failure, unspecified
0.716 0.284 0.000
S20-S29 Injuries to the thorax
0.715 0.285 0.000
I52 Other heart disorders in diseases classified elsewhere
0.714 0.285 0.000
I48 Atrial fibrillation and flutter
0.714 0.285 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.714 0.285 0.000
I41 Myocarditis in diseases classified elsewhere
0.714 0.285 0.000
I40 Acute myocarditis
0.714 0.285 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.714 0.285 0.000
I36 Nonrheumatic tricuspid valve disorders
0.714 0.285 0.000
I33 Acute and subacute endocarditis
0.714 0.285 0.000
I32 Pericarditis in diseases classified elsewhere
0.714 0.285 0.000
I30 Acute pericarditis
0.714 0.285 0.000
T87 Complications peculiar to reattachment and amputation
0.714 0.286 0.000
T86 Failure and rejection of transplanted organs and tissues
0.714 0.286 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.714 0.286 0.000
H90-H95 Other disorders of ear
0.714 0.286 0.000
C34.9 Bronchus or lung, unspecified
0.713 0.287 0.000
H55 Nystagmus and other irregular eye movements
0.713 0.287 0.000
I15 Secondary hypertension
0.712 0.288 0.000
I13 Hypertensive heart and renal disease
0.712 0.288 0.000
I20 Angina pectoris
0.712 0.288 0.000
S89 Other and unspecified injuries of lower leg
0.712 0.288 0.000
Q60-Q64 Congenital malformations of the urinary system
0.710 0.290 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.709 0.291 0.000
J09-J18 Influenza and pneumonia
0.707 0.293 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.707 0.293 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.707 0.293 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.707 0.293 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.707 0.293 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.707 0.293 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.707 0.293 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.707 0.293 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.707 0.293 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.707 0.293 0.000
T36 Poisoning by systemic antibiotics
0.707 0.293 0.000
E11 Non-insulin-dependent diabetes mellitus
0.706 0.294 0.000
H10-H13 Disorders of conjunctiva
0.706 0.294 0.000
N18.8 Other chronic renal failure
0.704 0.296 0.000
N18.1 Chronic kidney disease, stage 1
0.704 0.296 0.000
I44.6 Other and unspecified fascicular block
0.703 0.297 0.000
I44.5 Left posterior fascicular block
0.703 0.297 0.000
I44.4 Left anterior fascicular block
0.703 0.297 0.000
I44.3 Other and unspecified atrioventricular block
0.703 0.297 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.703 0.297 0.000
X60-X84 Intentional self-harm
0.703 0.297 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.702 0.298 0.000
S64.4 Injury of digital nerve of other finger
0.702 0.298 0.000
I09 Other rheumatic heart diseases
0.700 0.300 0.000
I06 Rheumatic aortic valve diseases
0.700 0.300 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.699 0.301 0.000
I05.9 Mitral valve disease, unspecified
0.699 0.301 0.000
E78.8 Other disorders of lipoprotein metabolism
0.697 0.303 0.000
E78.6 Lipoprotein deficiency
0.697 0.303 0.000
E78.4 Other hyperlipidaemia
0.697 0.303 0.000
E78.3 Hyperchylomicronaemia
0.697 0.303 0.000
E78.2 Mixed hyperlipidaemia
0.697 0.303 0.000
E78.1 Pure hyperglyceridaemia
0.697 0.303 0.000
T66-T78 Other and unspecified effects of external causes
0.697 0.303 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.696 0.304 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.696 0.304 0.000
S32 Fracture of lumbar spine and pelvis
0.696 0.304 0.000
Y43.4 Immunosuppressive agents
0.695 0.305 0.000
Y59 Other and unspecified vaccines and biological substances
0.695 0.305 0.000
Y58 Bacterial vaccines
0.695 0.305 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.695 0.305 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.695 0.305 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.695 0.305 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.695 0.305 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.695 0.305 0.000
Y48 Anaesthetics and therapeutic gases
0.695 0.305 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.695 0.305 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.695 0.305 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.695 0.305 0.000
Q50-Q56 Congenital malformations of genital organs
0.694 0.306 0.000
I24 Other acute ischaemic heart diseases
0.693 0.307 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.692 0.308 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.692 0.308 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.692 0.308 0.000
I38 Endocarditis, valve unspecified
0.692 0.308 0.000
S42 Fracture of shoulder and upper arm
0.691 0.309 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.691 0.309 0.000
I44.0 Atrioventricular block, first degree
0.690 0.310 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.689 0.311 0.000
H57 Other disorders of eye and adnexa
0.688 0.312 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.688 0.312 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.688 0.312 0.000
T39.4 Antirheumatics, not elsewhere classified
0.688 0.312 0.000
T39.2 Pyrazolone derivatives
0.688 0.312 0.000
V20-V29 Motorcycle rider injured in transport accident
0.687 0.312 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.687 0.313 0.000
J20-J22 Other acute lower respiratory infections
0.687 0.313 0.000
C44.9 Malignant neoplasm of skin, unspecified
0.687 0.313 0.000
C44.8 Overlapping lesion of skin
0.687 0.313 0.000
M70-M79 Other soft tissue disorders
0.687 0.313 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.684 0.316 0.000
I44.2 Atrioventricular block, complete
0.684 0.316 0.000
N05 Unspecified nephritic syndrome
0.683 0.316 0.000
E27 Other disorders of adrenal gland
0.683 0.317 0.000
Y43.3 Other antineoplastic drugs
0.683 0.317 0.000
W20-W49 Exposure to inanimate mechanical forces
0.681 0.319 0.000
E87.0 Hyperosmolality and hypernatraemia
0.681 0.319 0.000
H54.7 Unspecified visual loss
0.681 0.319 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.680 0.319 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.680 0.320 0.000
E87.4 Mixed disorder of acid-base balance
0.680 0.320 0.000
E87.3 Alkalosis
0.680 0.320 0.000
E23 Hypofunction and other disorders of pituitary gland
0.679 0.321 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.678 0.321 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.678 0.322 0.000
J30-J39 Other diseases of upper respiratory tract
0.677 0.323 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.676 0.324 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.676 0.324 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.676 0.324 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.676 0.324 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.675 0.325 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.675 0.325 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.675 0.325 0.000
N02.8 Other
0.675 0.325 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.675 0.325 0.000
E80.4 Gilbert's syndrome
0.672 0.328 0.000
V10-V19 Pedal cyclist injured in transport accident
0.671 0.329 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.670 0.330 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.670 0.330 0.000
E83 Disorders of mineral metabolism
0.670 0.330 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.670 0.330 0.000
N06 Isolated proteinuria with specified morphological lesion
0.670 0.330 0.000
N01 Rapidly progressive nephritic syndrome
0.670 0.330 0.000
N00 Acute nephritic syndrome
0.670 0.330 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.669 0.331 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.669 0.331 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.668 0.331 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.668 0.331 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.668 0.331 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.668 0.332 0.000
C15.5 Lower third of oesophagus
0.668 0.332 0.000
W18 Other fall on same level
0.667 0.333 0.000
W17 Other fall from one level to another
0.667 0.333 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.667 0.333 0.000
W15 Fall from cliff
0.667 0.333 0.000
W14 Fall from tree
0.667 0.333 0.000
W12 Fall on and from scaffolding
0.667 0.333 0.000
W11 Fall on and from ladder
0.667 0.333 0.000
W10 Fall on and from stairs and steps
0.667 0.333 0.000
W09 Fall involving playground equipment
0.667 0.333 0.000
W06 Fall involving bed
0.667 0.333 0.000
W05 Fall involving wheelchair
0.667 0.333 0.000
W04 Fall while being carried or supported by other persons
0.667 0.333 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.667 0.333 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.667 0.333 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.667 0.333 0.000
W00 Fall on same level involving ice and snow
0.667 0.333 0.000
C15.9 Oesophagus, unspecified
0.667 0.333 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.666 0.334 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.664 0.336 0.000
N99-N99 Other disorders of the genitourinary system
0.662 0.337 0.000
I08.9 Multiple valve disease, unspecified
0.662 0.338 0.000
I08.8 Other multiple valve diseases
0.662 0.338 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.662 0.338 0.000
E28 Ovarian dysfunction
0.662 0.338 0.000
Q00-Q07 Congenital malformations of the nervous system
0.662 0.338 0.000
E29 Testicular dysfunction
0.662 0.338 0.000
E22 Hyperfunction of pituitary gland
0.661 0.339 0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft
0.660 0.339 0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract
0.660 0.339 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.660 0.339 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.660 0.339 0.000
T83.2 Mechanical complication of graft of urinary organ
0.660 0.339 0.000
S92 Fracture of foot, except ankle
0.660 0.340 0.000
I82 Other venous embolism and thrombosis
0.660 0.340 0.000
S60 Superficial injury of wrist and hand
0.659 0.340 0.000
I25 Chronic ischaemic heart disease
0.659 0.341 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.659 0.341 0.000
E14 Unspecified diabetes mellitus
0.658 0.342 0.000
I87 Other disorders of veins
0.657 0.343 0.000
M80-M85 Disorders of bone density and structure
0.657 0.343 0.000
E03 Other hypothyroidism
0.657 0.343 0.000
M79.6 Pain in limb
0.655 0.345 0.000
S88 Traumatic amputation of lower leg
0.654 0.345 0.000
S87 Crushing injury of lower leg
0.654 0.345 0.000
S86 Injury of muscle and tendon at lower leg level
0.654 0.345 0.000
S85 Injury of blood vessels at lower leg level
0.654 0.345 0.000
S84 Injury of nerves at lower leg level
0.654 0.345 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.653 0.346 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.653 0.347 0.000
S69 Other and unspecified injuries of wrist and hand
0.652 0.348 0.000
S67 Crushing injury of wrist and hand
0.652 0.348 0.000
S65 Injury of blood vessels at wrist and hand level
0.652 0.348 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.652 0.348 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.649 0.351 0.000
H52 Disorders of refraction and accommodation
0.649 0.351 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.648 0.352 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.648 0.352 0.000
C31 Malignant neoplasm of accessory sinuses
0.648 0.352 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.648 0.352 0.000
C37 Malignant neoplasm of thymus
0.648 0.352 0.000
C33 Malignant neoplasm of trachea
0.648 0.352 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.648 0.352 0.000
I25.1 Atherosclerotic heart disease
0.647 0.353 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.647 0.353 0.000
E89.8 Other postprocedural endocrine and metabolic disorders
0.647 0.353 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.647 0.353 0.000
E89.5 Postprocedural testicular hypofunction
0.647 0.353 0.000
E89.4 Postprocedural ovarian failure
0.647 0.353 0.000
E89.3 Postprocedural hypopituitarism
0.647 0.353 0.000
E89.2 Postprocedural hypoparathyroidism
0.647 0.353 0.000
E89.1 Postprocedural hypoinsulinaemia
0.647 0.353 0.000
C51-C58 Malignant neoplasms of female genital organs
0.646 0.353 0.000
H53.1 Subjective visual disturbances
0.645 0.355 0.000
J02 Acute pharyngitis
0.644 0.356 0.000
T82.3 Mechanical complication of other vascular grafts
0.643 0.357 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.642 0.358 0.000
T39.0 Salicylates
0.642 0.358 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.642 0.358 0.000
I12.9 Hypertensive renal disease without renal failure
0.640 0.360 0.000
S72 Fracture of femur
0.640 0.360 0.000
J91 Pleural effusion in conditions classified elsewhere
0.639 0.360 0.000
W13.9 Unspecified place
0.639 0.361 0.000
Y45.1 Salicylates
0.639 0.361 0.000
H30-H36 Disorders of choroid and retina
0.638 0.362 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.638 0.362 0.000
Q80-Q89 Other congenital malformations
0.638 0.362 0.000
Q35-Q37 Cleft lip and cleft palate
0.638 0.362 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.638 0.362 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.638 0.362 0.000
M79.66 Pain in limb (Lower leg)
0.638 0.362 0.000
M40-M43 Deforming dorsopathies
0.638 0.362 0.000
Y57.9 Drug or medicament, unspecified
0.637 0.362 0.000
H53.2 Diplopia
0.637 0.363 0.000
S80.8 Other superficial injuries of lower leg
0.637 0.363 0.000
T93 Sequelae of injuries of lower limb
0.636 0.364 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.636 0.364 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.636 0.364 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.633 0.367 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.631 0.369 0.000
I46 Cardiac arrest
0.631 0.369 0.000
Y86 Sequelae of other accidents
0.630 0.369 0.000
S68 Traumatic amputation of wrist and hand
0.630 0.370 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.629 0.371 0.000
Y43.9 Primarily systemic agent, unspecified
0.629 0.371 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.629 0.371 0.000
Y43.6 Enzymes, not elsewhere classified
0.629 0.371 0.000
Y43.5 Acidifying and alkalising agents
0.629 0.371 0.000
Y43.2 Antineoplastic natural products
0.629 0.371 0.000
Y43.0 Antiallergic and antiemetic drugs
0.629 0.371 0.000
S80.1 Contusion of other and unspecified parts of lower leg
0.628 0.372 0.000
J98.8 Other specified respiratory disorders
0.628 0.372 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.627 0.373 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.626 0.374 0.000
T91 Sequelae of injuries of neck and trunk
0.625 0.375 0.000
D55-D59 Haemolytic anaemias
0.625 0.375 0.000
S62.4 Multiple fractures of metacarpal bones
0.624 0.375 0.000
H71 Cholesteatoma of middle ear
0.624 0.376 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.623 0.376 0.000
J90 Pleural effusion, not elsewhere classified
0.623 0.377 0.000
I05.8 Other mitral valve diseases
0.622 0.378 0.000
I05.2 Mitral stenosis with insufficiency
0.622 0.378 0.000
I05.1 Rheumatic mitral insufficiency
0.622 0.378 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.622 0.378 0.000
E34 Other endocrine disorders
0.622 0.378 0.000
E32 Diseases of thymus
0.622 0.378 0.000
E31 Polyglandular dysfunction
0.622 0.378 0.000
E30 Disorders of puberty, not elsewhere classified
0.622 0.378 0.000
E26 Hyperaldosteronism
0.622 0.378 0.000
E25 Adrenogenital disorders
0.622 0.378 0.000
E24 Cushing's syndrome
0.622 0.378 0.000
E20 Hypoparathyroidism
0.622 0.378 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.621 0.379 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.621 0.379 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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