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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs114609132
log Bayes Factor = 14.2901
Chromosome 2   position 1,551,467  (GRCh37) Explore rs114609132 on Ensembl!
Variant rs114609132 is part of Cluster X0176

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter II Neoplasms
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.998 0.002 0.000
Chapter X Diseases of the respiratory system
0.998 0.002 0.000
C15-C26 Malignant neoplasms of digestive organs
0.998 0.002 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.995 0.005 0.000
Chapter XIV Diseases of the genitourinary system
0.995 0.005 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.992 0.008 0.000
Chapter XX External causes of morbidity and mortality
0.991 0.009 0.000
J30-J39 Other diseases of upper respiratory tract
0.988 0.012 0.000
Chapter I Certain infectious and parasitic diseases
0.984 0.016 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.983 0.017 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.978 0.022 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.975 0.025 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.973 0.027 0.000
E00-E07 Disorders of thyroid gland
0.970 0.030 0.000
E70-E90 Metabolic disorders
0.969 0.031 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.964 0.036 0.000
J34 Other disorders of nose and nasal sinuses
0.950 0.050 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.948 0.052 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.947 0.053 0.000
Z51 Other medical care
0.943 0.057 0.000
S80-S89 Injuries to the knee and lower leg
0.942 0.058 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.938 0.062 0.000
E03 Other hypothyroidism
0.937 0.063 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.937 0.063 0.000
R50-R69 General symptoms and signs
0.935 0.065 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.935 0.065 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.931 0.069 0.000
B95-B98 Bacterial, viral and other infectious agents
0.926 0.074 0.000
A30-A49 Other bacterial diseases
0.926 0.074 0.000
Y43 Primarily systemic agents
0.923 0.077 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.923 0.077 0.000
Z51.1 Chemotherapy session for neoplasm
0.920 0.080 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.917 0.083 0.000
E03.9 Hypothyroidism, unspecified
0.915 0.085 0.000
J40-J47 Chronic lower respiratory diseases
0.914 0.086 0.000
J90-J94 Other diseases of pleura
0.913 0.087 0.000
C18 Malignant neoplasm of colon
0.912 0.088 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.911 0.089 0.000
N30-N39 Other diseases of urinary system
0.907 0.093 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.906 0.094 0.000
Z43 Attention to artificial openings
0.904 0.096 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.903 0.097 0.000
J44 Other chronic obstructive pulmonary disease
0.903 0.097 0.000
R50 Fever of unknown origin
0.902 0.098 0.000
R55 Syncope and collapse
0.899 0.101 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.897 0.103 0.000
N60-N64 Disorders of breast
0.894 0.106 0.000
C20 Malignant neoplasm of rectum
0.893 0.107 0.000
T81 Complications of procedures, not elsewhere classified
0.889 0.111 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.886 0.114 0.000
N93 Other abnormal uterine and vaginal bleeding
0.885 0.115 0.000
J34.2 Deviated nasal septum
0.884 0.116 0.000
Y43.3 Other antineoplastic drugs
0.884 0.116 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.881 0.119 0.000
R50.9 Fever, unspecified
0.878 0.122 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.877 0.123 0.000
D70 Agranulocytosis
0.876 0.124 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.873 0.127 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.873 0.127 0.000
J34.3 Hypertrophy of nasal turbinates
0.871 0.129 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.871 0.129 0.000
N87 Dysplasia of cervix uteri
0.867 0.133 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.866 0.134 0.000
Z72 Problems related to lifestyle
0.864 0.136 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.863 0.137 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.863 0.137 0.000
Chapter V Mental and behavioural disorders
0.854 0.146 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.851 0.149 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.851 0.149 0.000
N39 Other disorders of urinary system
0.851 0.149 0.000
J33 Nasal polyp
0.848 0.152 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.848 0.152 0.000
A41 Other septicaemia
0.848 0.152 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.848 0.152 0.000
E86 Volume depletion
0.843 0.157 0.000
Chapter XXII Codes for special purposes
0.842 0.158 0.000
Z46 Fitting and adjustment of other devices
0.842 0.158 0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm
0.842 0.158 0.000
Z72.0 Tobacco use
0.840 0.160 0.000
J90 Pleural effusion, not elsewhere classified
0.839 0.161 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.838 0.162 0.000
C45 Mesothelioma
0.834 0.166 0.000
S20-S29 Injuries to the thorax
0.832 0.168 0.000
E83 Disorders of mineral metabolism
0.832 0.168 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.830 0.170 0.000
R52 Pain, not elsewhere classified
0.827 0.173 0.000
S82 Fracture of lower leg, including ankle
0.827 0.173 0.000
Y40 Systemic antibiotics
0.826 0.174 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.825 0.175 0.000
R59 Enlarged lymph nodes
0.825 0.175 0.000
N80 Endometriosis
0.821 0.179 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.819 0.181 0.000
O60-O75 Complications of labour and delivery
0.816 0.184 0.000
Z43.2 Attention to ileostomy
0.816 0.184 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.815 0.185 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.815 0.185 0.000
C16 Malignant neoplasm of stomach
0.814 0.186 0.000
N85.8 Other specified noninflammatory disorders of uterus
0.814 0.186 0.000
Z45 Adjustment and management of implanted device
0.814 0.186 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.811 0.189 0.000
Y95 Nosocomial condition
0.811 0.189 0.000
C15 Malignant neoplasm of oesophagus
0.809 0.190 0.000
J35 Chronic diseases of tonsils and adenoids
0.809 0.191 0.000
N39.0 Urinary tract infection, site not specified
0.809 0.191 0.000
N25-N29 Other disorders of kidney and ureter
0.807 0.193 0.000
Z53.0 Procedure not carried out because of contraindication
0.807 0.193 0.000
Z09.8 Follow-up examination after other treatment for other conditions
0.806 0.194 0.000
C18.6 Descending colon
0.806 0.194 0.000
B35-B49 Mycoses
0.806 0.194 0.000
D00-D09 In situ neoplasms
0.805 0.195 0.000
Z53.8 Procedure not carried out for other reasons
0.803 0.197 0.000
A41.9 Septicaemia, unspecified
0.801 0.199 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.801 0.199 0.000
X60-X84 Intentional self-harm
0.800 0.200 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.798 0.202 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.798 0.202 0.000
N17-N19 Renal failure
0.798 0.202 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.795 0.205 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.793 0.207 0.000
N64 Other disorders of breast
0.792 0.208 0.000
D69 Purpura and other haemorrhagic conditions
0.791 0.209 0.000
D73 Diseases of spleen
0.790 0.210 0.000
T79-T79 Certain early complications of trauma
0.787 0.213 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.786 0.214 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.785 0.215 0.000
A49 Bacterial infection of unspecified site
0.784 0.216 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.783 0.217 0.000
Z51.2 Other chemotherapy
0.782 0.218 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.781 0.219 0.000
Z01.8 Other specified special examinations
0.779 0.221 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.778 0.221 0.000
Z71.9 Counselling, unspecified
0.775 0.225 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.774 0.226 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.774 0.226 0.000
N88 Other noninflammatory disorders of cervix uteri
0.774 0.226 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.774 0.226 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.773 0.227 0.000
V80-V89 Other land transport accidents
0.772 0.228 0.000
E87.7 Fluid overload
0.772 0.228 0.000
N99-N99 Other disorders of the genitourinary system
0.772 0.228 0.000
T66-T78 Other and unspecified effects of external causes
0.770 0.230 0.000
N30 Cystitis
0.770 0.230 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.769 0.231 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.768 0.232 0.000
D68 Other coagulation defects
0.768 0.232 0.000
N39.3 Stress incontinence
0.767 0.233 0.000
J30 Vasomotor and allergic rhinitis
0.766 0.234 0.000
N87.9 Dysplasia of cervix uteri, unspecified
0.766 0.234 0.000
F30-F39 Mood [affective] disorders
0.764 0.236 0.000
S90-S99 Injuries to the ankle and foot
0.764 0.236 0.000
C25 Malignant neoplasm of pancreas
0.763 0.237 0.000
R69 Unknown and unspecified causes of morbidity
0.762 0.238 0.000
Z53.9 Procedure not carried out, unspecified reason
0.762 0.238 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.760 0.240 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.759 0.241 0.000
N62 Hypertrophy of breast
0.759 0.241 0.000
N93.0 Postcoital and contact bleeding
0.756 0.244 0.000
Z13 Special screening examination for other diseases and disorders
0.753 0.247 0.000
J31.0 Chronic rhinitis
0.753 0.247 0.000
E04 Other non-toxic goitre
0.750 0.250 0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.750 0.250 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.750 0.250 0.000
Z02 Examination and encounter for administrative purposes
0.749 0.251 0.000
Z42 Follow-up care involving plastic surgery
0.749 0.251 0.000
D46 Myelodysplastic syndromes
0.746 0.254 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.746 0.254 0.000
E87.6 Hypokalaemia
0.746 0.254 0.000
E89.0 Postprocedural hypothyroidism
0.744 0.256 0.000
N19 Unspecified renal failure
0.743 0.257 0.000
C51-C58 Malignant neoplasms of female genital organs
0.741 0.259 0.000
E10-E14 Diabetes mellitus
0.740 0.260 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.739 0.260 0.000
C78.7 Secondary malignant neoplasm of liver
0.739 0.261 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.739 0.261 0.000
E20-E35 Disorders of other endocrine glands
0.739 0.261 0.000
C45.0 Mesothelioma of pleura
0.739 0.261 0.000
R63 Symptoms and signs concerning food and fluid intake
0.738 0.262 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.738 0.262 0.000
D72 Other disorders of white blood cells
0.738 0.262 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.737 0.263 0.000
Z41 Procedures for purposes other than remedying health state
0.737 0.263 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.736 0.263 0.000
S70-S79 Injuries to the hip and thigh
0.736 0.264 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.736 0.264 0.000
Y52 Agents primarily affecting the cardiovascular system
0.735 0.264 0.000
Z43.1 Attention to gastrostomy
0.734 0.266 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.732 0.268 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.732 0.268 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.732 0.268 0.000
Z49 Care involving dialysis
0.731 0.269 0.000
N80.1 Endometriosis of ovary
0.730 0.270 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.729 0.271 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.728 0.272 0.000
J09-J18 Influenza and pneumonia
0.728 0.272 0.000
Y44 Agents primarily affecting blood constituents
0.727 0.273 0.000
B15-B19 Viral hepatitis
0.726 0.274 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.725 0.275 0.000
M05-M14 Inflammatory polyarthropathies
0.724 0.276 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.723 0.277 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.722 0.278 0.000
N92 Excessive, frequent and irregular menstruation
0.721 0.279 0.000
T39.1 4-Aminophenol derivatives
0.720 0.280 0.000
J42 Unspecified chronic bronchitis
0.718 0.282 0.000
N93.9 Abnormal uterine and vaginal bleeding, unspecified
0.718 0.282 0.000
J95-J99 Other diseases of the respiratory system
0.718 0.282 0.000
Z73 Problems related to life-management difficulty
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
S80 Superficial injury of lower leg
0.716 0.283 0.000
Y40.0 Penicillins
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.716 0.284 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.716 0.284 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.284 0.000
C18.7 Sigmoid colon
0.716 0.284 0.000
O47 False labour
0.716 0.284 0.000
J33.9 Nasal polyp, unspecified
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
S10-S19 Injuries to the neck
0.716 0.284 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.715 0.285 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.715 0.285 0.000
C21 Malignant neoplasm of anus and anal canal
0.715 0.285 0.000
C17 Malignant neoplasm of small intestine
0.715 0.285 0.000
C23 Malignant neoplasm of gallbladder
0.715 0.285 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.715 0.285 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.714 0.286 0.000
E40-E46 Malnutrition
0.713 0.286 0.000
R57 Shock, not elsewhere classified
0.713 0.287 0.000
C45.9 Mesothelioma, unspecified
0.712 0.288 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.712 0.288 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.712 0.288 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.712 0.288 0.000
Z54 Convalescence
0.711 0.288 0.000
Z52 Donors of organs and tissues
0.711 0.288 0.000
Z44 Fitting and adjustment of external prosthetic device
0.711 0.288 0.000
S83.2 Tear of meniscus, current
0.711 0.289 0.000
R68 Other general symptoms and signs
0.711 0.289 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.711 0.289 0.000
Y35-Y36 Legal intervention and operations of war
0.711 0.289 0.000
Y10-Y34 Event of undetermined intent
0.711 0.289 0.000
Y00-Y09 Assault
0.711 0.289 0.000
X85-X99 Assault
0.711 0.289 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.711 0.289 0.000
X50-X57 Overexertion, travel and privation
0.711 0.289 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.711 0.289 0.000
X30-X39 Exposure to forces of nature
0.711 0.289 0.000
X20-X29 Contact with venomous animals and plants
0.711 0.289 0.000
X10-X19 Contact with heat and hot substances
0.711 0.289 0.000
X00-X09 Exposure to smoke, fire and flames
0.711 0.289 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.711 0.289 0.000
W75-W84 Other accidental threats to breathing
0.711 0.289 0.000
W65-W74 Accidental drowning and submersion
0.711 0.289 0.000
W50-W64 Exposure to animate mechanical forces
0.711 0.289 0.000
W20-W49 Exposure to inanimate mechanical forces
0.711 0.289 0.000
V98-V99 Other and unspecified transport accidents
0.711 0.289 0.000
V95-V97 Air and space transport accidents
0.711 0.289 0.000
V90-V94 Water transport accidents
0.711 0.289 0.000
V70-V79 Bus occupant injured in transport accident
0.711 0.289 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.711 0.289 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.711 0.289 0.000
V40-V49 Car occupant injured in transport accident
0.711 0.289 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.711 0.289 0.000
V20-V29 Motorcycle rider injured in transport accident
0.711 0.289 0.000
V01-V09 Pedestrian injured in transport accident
0.711 0.289 0.000
D69.6 Thrombocytopenia, unspecified
0.711 0.289 0.000
C80 Malignant neoplasm without specification of site
0.710 0.289 0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm
0.710 0.290 0.000
Z74 Problems related to care-provider dependency
0.710 0.290 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.710 0.290 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.709 0.290 0.000
J37 Chronic laryngitis and laryngotracheitis
0.709 0.291 0.000
J91 Pleural effusion in conditions classified elsewhere
0.708 0.292 0.000
N63 Unspecified lump in breast
0.708 0.292 0.000
Z13.6 Special screening examination for cardiovascular disorders
0.708 0.292 0.000
Z45.8 Adjustment and management of other implanted devices
0.707 0.293 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.706 0.294 0.000
Z46.6 Fitting and adjustment of urinary device
0.706 0.294 0.000
B99-B99 Other infectious diseases
0.706 0.294 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.706 0.294 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.706 0.294 0.000
B65-B83 Helminthiases
0.706 0.294 0.000
B50-B64 Protozoal diseases
0.706 0.294 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.706 0.294 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.706 0.294 0.000
A80-A89 Viral infections of the central nervous system
0.706 0.294 0.000
A75-A79 Rickettsioses
0.706 0.294 0.000
A70-A74 Other diseases caused by chlamydiae
0.706 0.294 0.000
A65-A69 Other spirochaetal diseases
0.706 0.294 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.706 0.294 0.000
A20-A28 Certain zoonotic bacterial diseases
0.706 0.294 0.000
A15-A19 Tuberculosis
0.706 0.294 0.000
Z10 Routine general health check-up of defined subpopulation
0.704 0.295 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.704 0.295 0.000
J00-J06 Acute upper respiratory infections
0.704 0.296 0.000
E83.4 Disorders of magnesium metabolism
0.704 0.296 0.000
M70-M79 Other soft tissue disorders
0.703 0.297 0.000
S82.8 Fractures of other parts of lower leg
0.702 0.298 0.000
Y59 Other and unspecified vaccines and biological substances
0.701 0.299 0.000
Y58 Bacterial vaccines
0.701 0.299 0.000
Y57 Other and unspecified drugs and medicaments
0.701 0.299 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.701 0.299 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.701 0.299 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.701 0.299 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.701 0.299 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.701 0.299 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.701 0.299 0.000
Y48 Anaesthetics and therapeutic gases
0.701 0.299 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.701 0.299 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.701 0.299 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.701 0.299 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.701 0.299 0.000
N98 Complications associated with artificial fertilisation
0.699 0.301 0.000
N91 Absent, scanty and rare menstruation
0.699 0.301 0.000
N82 Fistulae involving female genital tract
0.699 0.301 0.000
N96 Habitual aborter
0.699 0.301 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.699 0.301 0.000
S89 Other and unspecified injuries of lower leg
0.699 0.301 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.698 0.302 0.000
D55-D59 Haemolytic anaemias
0.697 0.303 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.697 0.303 0.000
N93.8 Other specified abnormal uterine and vaginal bleeding
0.697 0.303 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.696 0.303 0.000
N10-N16 Renal tubulo-interstitial diseases
0.696 0.304 0.000
C18.4 Transverse colon
0.696 0.304 0.000
E06 Thyroiditis
0.695 0.305 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.695 0.305 0.000
E00 Congenital iodine-deficiency syndrome
0.695 0.305 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.695 0.305 0.000
Z75 Problems related to medical facilities and other health care
0.695 0.305 0.000
E85 Amyloidosis
0.695 0.305 0.000
E84 Cystic fibrosis
0.695 0.305 0.000
E79 Disorders of purine and pyrimidine metabolism
0.695 0.305 0.000
E77 Disorders of glycoprotein metabolism
0.695 0.305 0.000
E76 Disorders of glycosaminoglycan metabolism
0.695 0.305 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.695 0.305 0.000
E74 Other disorders of carbohydrate metabolism
0.695 0.305 0.000
E73 Lactose intolerance
0.695 0.305 0.000
E72 Other disorders of amino-acid metabolism
0.695 0.305 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.695 0.305 0.000
E70 Disorders of aromatic amino-acid metabolism
0.695 0.305 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.695 0.305 0.000
J94 Other pleural conditions
0.694 0.306 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.694 0.306 0.000
Z04 Examination and observation for other reasons
0.694 0.306 0.000
N81 Female genital prolapse
0.694 0.306 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.692 0.308 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.691 0.309 0.000
E88 Other metabolic disorders
0.691 0.309 0.000
Y45.0 Opioids and related analgesics
0.691 0.309 0.000
Z76 Persons encountering health services in other circumstances
0.691 0.309 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.691 0.309 0.000
Z09.9 Follow-up examination after unspecified treatment for other conditions
0.690 0.310 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.688 0.312 0.000
S81 Open wound of lower leg
0.688 0.312 0.000
J92 Pleural plaque
0.688 0.312 0.000
R52.0 Acute pain
0.687 0.313 0.000
N00-N08 Glomerular diseases
0.687 0.313 0.000
M80-M85 Disorders of bone density and structure
0.686 0.314 0.000
D80-D89 Certain disorders involving the immune mechanism
0.685 0.314 0.000
C18.9 Colon, unspecified
0.685 0.315 0.000
N84 Polyp of female genital tract
0.684 0.316 0.000
S50-S59 Injuries to the elbow and forearm
0.684 0.316 0.000
D73.0 Hyposplenism
0.684 0.316 0.000
J60-J70 Lung diseases due to external agents
0.683 0.316 0.000
D75 Other diseases of blood and blood-forming organs
0.683 0.317 0.000
C64-C68 Malignant neoplasms of urinary tract
0.683 0.317 0.000
A49.0 Staphylococcal infection, unspecified
0.683 0.317 0.000
J34.1 Cyst and mucocele of nose and nasal sinus
0.681 0.319 0.000
J34.0 Abscess, furuncle and carbuncle of nose
0.681 0.319 0.000
R52.2 Other chronic pain
0.681 0.319 0.000
E07 Other disorders of thyroid
0.680 0.320 0.000
T87 Complications peculiar to reattachment and amputation
0.680 0.320 0.000
T86 Failure and rejection of transplanted organs and tissues
0.680 0.320 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.680 0.320 0.000
F31 Bipolar affective disorder
0.679 0.321 0.000
V10-V19 Pedal cyclist injured in transport accident
0.679 0.321 0.000
Z09.2 Follow-up examination after chemotherapy for other conditions
0.679 0.321 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.679 0.321 0.000
R59.1 Generalised enlarged lymph nodes
0.678 0.322 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.678 0.322 0.000
B37 Candidiasis
0.677 0.323 0.000
T40.2 Other opioids
0.677 0.323 0.000
N94.6 Dysmenorrhoea, unspecified
0.676 0.324 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.676 0.324 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.676 0.324 0.000
Z51.9 Medical care, unspecified
0.676 0.324 0.000
Z51.6 Desensitisation to allergens
0.676 0.324 0.000
S88 Traumatic amputation of lower leg
0.675 0.324 0.000
S87 Crushing injury of lower leg
0.675 0.324 0.000
S86 Injury of muscle and tendon at lower leg level
0.675 0.324 0.000
S85 Injury of blood vessels at lower leg level
0.675 0.324 0.000
S84 Injury of nerves at lower leg level
0.675 0.324 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.675 0.325 0.000
D68.2 Hereditary deficiency of other clotting factors
0.675 0.325 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.675 0.325 0.000
C16.0 Cardia
0.675 0.325 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.673 0.327 0.000
J35.8 Other chronic diseases of tonsils and adenoids
0.673 0.327 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.672 0.327 0.000
D74 Methaemoglobinaemia
0.672 0.327 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.672 0.327 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.672 0.327 0.000
Z71.8 Other specified counselling
0.672 0.328 0.000
Z01.5 Diagnostic skin and sensitisation tests
0.672 0.328 0.000
E03.8 Other specified hypothyroidism
0.672 0.328 0.000
E03.5 Myxoedema coma
0.672 0.328 0.000
E03.4 Atrophy of thyroid (acquired)
0.672 0.328 0.000
E03.3 Postinfectious hypothyroidism
0.672 0.328 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.672 0.328 0.000
E03.1 Congenital hypothyroidism without goitre
0.672 0.328 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.672 0.328 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.672 0.328 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.672 0.328 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.672 0.328 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.672 0.328 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.672 0.328 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.672 0.328 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.672 0.328 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.672 0.328 0.000
T36 Poisoning by systemic antibiotics
0.672 0.328 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.672 0.328 0.000
Z51.8 Other specified medical care
0.671 0.329 0.000
E05.9 Thyrotoxicosis, unspecified
0.671 0.329 0.000
W00-W19 Falls
0.671 0.329 0.000
Z71.1 Person with feared complaint in whom no diagnosis is made
0.671 0.329 0.000
D41.4 Bladder
0.671 0.329 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.670 0.330 0.000
R62 Lack of expected normal physiological development
0.670 0.330 0.000
R64 Cachexia
0.670 0.330 0.000
R58 Haemorrhage, not elsewhere classified
0.670 0.330 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.670 0.330 0.000
N87.0 Mild cervical dysplasia
0.669 0.331 0.000
J38.0 Paralysis of vocal cords and larynx
0.669 0.331 0.000
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure
0.668 0.332 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.667 0.333 0.000
N64.1 Fat necrosis of breast
0.667 0.333 0.000
C22.9 Liver, unspecified
0.667 0.333 0.000
R63.0 Anorexia
0.666 0.334 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.666 0.334 0.000
R59.0 Localised enlarged lymph nodes
0.664 0.335 0.000
E50-E64 Other nutritional deficiencies
0.664 0.336 0.000
A48 Other bacterial diseases, not elsewhere classified
0.664 0.336 0.000
A44 Bartonellosis
0.664 0.336 0.000
A43 Nocardiosis
0.664 0.336 0.000
A42 Actinomycosis
0.664 0.336 0.000
A40 Streptococcal septicaemia
0.664 0.336 0.000
A39 Meningococcal infection
0.664 0.336 0.000
A37 Whooping cough
0.664 0.336 0.000
A36 Diphtheria
0.664 0.336 0.000
A32 Listeriosis
0.664 0.336 0.000
A31 Infection due to other mycobacteria
0.664 0.336 0.000
A30 Leprosy [Hansen's disease]
0.664 0.336 0.000
A46 Erysipelas
0.664 0.336 0.000
A38 Scarlet fever
0.664 0.336 0.000
A35 Other tetanus
0.664 0.336 0.000
A34 Obstetrical tetanus
0.664 0.336 0.000
A33 Tetanus neonatorum
0.664 0.336 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.663 0.337 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.663 0.337 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.663 0.337 0.000
M79.6 Pain in limb
0.662 0.338 0.000
R61 Hyperhidrosis
0.662 0.338 0.000
Y43.9 Primarily systemic agent, unspecified
0.662 0.338 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.662 0.338 0.000
Y43.6 Enzymes, not elsewhere classified
0.662 0.338 0.000
Y43.5 Acidifying and alkalising agents
0.662 0.338 0.000
Y43.4 Immunosuppressive agents
0.662 0.338 0.000
Y43.2 Antineoplastic natural products
0.662 0.338 0.000
Y43.1 Antineoplastic antimetabolites
0.662 0.338 0.000
Y43.0 Antiallergic and antiemetic drugs
0.662 0.338 0.000
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm
0.662 0.338 0.000
J33.8 Other polyp of sinus
0.662 0.338 0.000
D06 Carcinoma in situ of cervix uteri
0.661 0.339 0.000
R53 Malaise and fatigue
0.661 0.339 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.660 0.340 0.000
Z71.3 Dietary counselling and surveillance
0.660 0.340 0.000
C18.2 Ascending colon
0.659 0.341 0.000
S82.5 Fracture of medial malleolus
0.659 0.341 0.000
N89 Other noninflammatory disorders of vagina
0.658 0.341 0.000
C22.1 Intrahepatic bile duct carcinoma
0.658 0.342 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.658 0.342 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.657 0.342 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.657 0.342 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.657 0.342 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.657 0.342 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.657 0.342 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.657 0.342 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.657 0.342 0.000
Z47 Other orthopaedic follow-up care
0.657 0.343 0.000
D60-D64 Aplastic and other anaemias
0.657 0.343 0.000
F60-F69 Disorders of adult personality and behaviour
0.656 0.344 0.000
J41 Simple and mucopurulent chronic bronchitis
0.655 0.345 0.000
J46 Status asthmaticus
0.655 0.345 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.654 0.346 0.000
C18.8 Overlapping lesion of colon
0.654 0.346 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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