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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs114623553
log Bayes Factor = 11.967
Chromosome 4   position 54,387,668  (GRCh37) Explore rs114623553 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
0.998 0.002 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.996 0.004 0.000
I20-I25 Ischaemic heart diseases
0.996 0.004 0.000
O60-O75 Complications of labour and delivery
0.995 0.005 0.000
M70-M79 Other soft tissue disorders
0.992 0.008 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.992 0.008 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.987 0.013 0.000
M75 Shoulder lesions
0.985 0.015 0.000
I21 Acute myocardial infarction
0.982 0.018 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.978 0.022 0.000
I77 Other disorders of arteries and arterioles
0.976 0.024 0.000
I73 Other peripheral vascular diseases
0.975 0.025 0.000
M45-M49 Spondylopathies
0.971 0.029 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.968 0.032 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.965 0.035 0.000
I25 Chronic ischaemic heart disease
0.965 0.035 0.000
I73.9 Peripheral vascular disease, unspecified
0.965 0.035 0.000
M05-M14 Inflammatory polyarthropathies
0.960 0.040 0.000
M65-M68 Disorders of synovium and tendon
0.951 0.049 0.000
I25.2 Old myocardial infarction
0.950 0.050 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.945 0.055 0.000
O63 Long labour
0.941 0.059 0.000
M75.4 Impingement syndrome of shoulder
0.939 0.061 0.000
M65 Synovitis and tenosynovitis
0.928 0.072 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.926 0.074 0.000
I60-I69 Cerebrovascular diseases
0.925 0.075 0.000
M50-M54 Other dorsopathies
0.920 0.080 0.000
M65.3 Trigger finger
0.917 0.083 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.915 0.085 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.914 0.086 0.000
M46 Other inflammatory spondylopathies
0.911 0.089 0.000
S20-S29 Injuries to the thorax
0.910 0.090 0.000
M65.34 Trigger finger-Hand
0.910 0.090 0.000
M80-M85 Disorders of bone density and structure
0.909 0.091 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.903 0.097 0.000
Chapter I Certain infectious and parasitic diseases
0.902 0.098 0.000
M75.1 Rotator cuff syndrome
0.899 0.101 0.000
W20-W49 Exposure to inanimate mechanical forces
0.894 0.106 0.000
Y45.0 Opioids and related analgesics
0.892 0.108 0.000
M10 Gout
0.890 0.109 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.889 0.111 0.000
O43 Placental disorders
0.887 0.113 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.885 0.115 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.884 0.116 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.881 0.119 0.000
Chapter V Mental and behavioural disorders
0.881 0.119 0.000
O70 Perineal laceration during delivery
0.878 0.122 0.000
I25.1 Atherosclerotic heart disease
0.875 0.125 0.000
M54 Dorsalgia
0.874 0.126 0.000
I67 Other cerebrovascular diseases
0.873 0.127 0.000
I24 Other acute ischaemic heart diseases
0.869 0.131 0.000
O47 False labour
0.868 0.132 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.868 0.132 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.867 0.133 0.000
M75.0 Adhesive capsulitis of shoulder
0.864 0.136 0.000
O63.9 Long labour, unspecified
0.863 0.137 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.862 0.138 0.000
B95-B98 Bacterial, viral and other infectious agents
0.862 0.138 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.861 0.139 0.000
I10-I15 Hypertensive diseases
0.861 0.139 0.000
M40-M43 Deforming dorsopathies
0.858 0.142 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.853 0.147 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.853 0.147 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.853 0.147 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.853 0.147 0.000
I77.1 Stricture of artery
0.849 0.151 0.000
O36 Maternal care for other known or suspected foetal problems
0.846 0.154 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.844 0.156 0.000
F30-F39 Mood [affective] disorders
0.842 0.158 0.000
M10.9 Gout, unspecified
0.841 0.159 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.841 0.159 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.839 0.161 0.000
T43.2 Other and unspecified antidepressants
0.839 0.161 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.837 0.163 0.000
Chapter XXI Factors influencing health status and contact with health services
0.836 0.164 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.831 0.169 0.000
O72 Postpartum haemorrhage
0.829 0.171 0.000
I67.8 Other specified cerebrovascular diseases
0.826 0.174 0.000
S90-S99 Injuries to the ankle and foot
0.825 0.175 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.824 0.176 0.000
M86-M90 Other osteopathies
0.823 0.177 0.000
S10-S19 Injuries to the neck
0.818 0.182 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.818 0.182 0.000
O40 Polyhydramnios
0.816 0.184 0.000
M45 Ankylosing spondylitis
0.813 0.187 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.812 0.188 0.000
M00-M03 Infectious arthropathies
0.812 0.188 0.000
M14 Arthropathies in other diseases classified elsewhere
0.812 0.188 0.000
Chapter XI Diseases of the digestive system
0.811 0.189 0.000
I21.9 Acute myocardial infarction, unspecified
0.810 0.190 0.000
I77.8 Other specified disorders of arteries and arterioles
0.810 0.190 0.000
M75.5 Bursitis of shoulder
0.809 0.191 0.000
T93 Sequelae of injuries of lower limb
0.808 0.192 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.808 0.192 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.807 0.193 0.000
Chapter XXII Codes for special purposes
0.804 0.196 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.804 0.196 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.801 0.199 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.796 0.203 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.796 0.204 0.000
I77.0 Arteriovenous fistula, acquired
0.795 0.205 0.000
K04 Diseases of pulp and periapical tissues
0.794 0.206 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.794 0.206 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.794 0.206 0.000
I24.8 Other forms of acute ischaemic heart disease
0.794 0.206 0.000
I77.6 Arteritis, unspecified
0.792 0.208 0.000
M77 Other enthesopathies
0.790 0.210 0.000
O43.1 Malformation of placenta
0.787 0.213 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.785 0.214 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.783 0.217 0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)
0.782 0.218 0.000
M48 Other spondylopathies
0.777 0.223 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.777 0.223 0.000
O34.4 Maternal care for other abnormalities of cervix
0.777 0.223 0.000
X60-X84 Intentional self-harm
0.776 0.224 0.000
O61 Failed induction of labour
0.776 0.224 0.000
M54.1 Radiculopathy
0.775 0.225 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.775 0.225 0.000
Y44 Agents primarily affecting blood constituents
0.772 0.228 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.771 0.229 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.769 0.231 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.768 0.232 0.000
M51 Other intervertebral disk disorders
0.768 0.232 0.000
T42.4 Benzodiazepines
0.768 0.232 0.000
M84 Disorders of continuity of bone
0.768 0.232 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.767 0.233 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.766 0.234 0.000
I72 Other aneurysm
0.765 0.235 0.000
Y52 Agents primarily affecting the cardiovascular system
0.765 0.235 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.764 0.236 0.000
O62 Abnormalities of forces of labour
0.764 0.236 0.000
F32 Depressive episode
0.763 0.237 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.762 0.238 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.761 0.239 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.758 0.242 0.000
I21.4 Acute subendocardial myocardial infarction
0.757 0.243 0.000
O63.0 Prolonged first stage (of labour)
0.756 0.244 0.000
M81 Osteoporosis without pathological fracture
0.756 0.244 0.000
O63.1 Prolonged second stage (of labour)
0.755 0.245 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.754 0.246 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.754 0.246 0.000
O70.1 Second degree perineal laceration during delivery
0.754 0.246 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.753 0.247 0.000
V80-V89 Other land transport accidents
0.752 0.248 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.752 0.248 0.000
M05 Seropositive rheumatoid arthritis
0.750 0.250 0.000
T87 Complications peculiar to reattachment and amputation
0.750 0.250 0.000
Y95 Nosocomial condition
0.749 0.251 0.000
M20-M25 Other joint disorders
0.748 0.252 0.000
I71 Aortic aneurysm and dissection
0.748 0.252 0.000
O42 Premature rupture of membranes
0.745 0.255 0.000
M10.99 Gout, unspecified (Site unspecified)
0.744 0.256 0.000
M07 Psoriatic and enteropathic arthropathies
0.743 0.257 0.000
M11 Other crystal arthropathies
0.742 0.258 0.000
S29 Other and unspecified injuries of thorax
0.742 0.258 0.000
M54.3 Sciatica
0.741 0.259 0.000
O73 Retained placenta and membranes, without haemorrhage
0.741 0.259 0.000
M75.9 Shoulder lesion, unspecified
0.741 0.259 0.000
M43 Other deforming dorsopathies
0.740 0.259 0.000
O70.0 First degree perineal laceration during delivery
0.740 0.260 0.000
W00-W19 Falls
0.739 0.261 0.000
T79-T79 Certain early complications of trauma
0.737 0.263 0.000
M76 Enthesopathies of lower limb, excluding foot
0.736 0.264 0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.736 0.264 0.000
M54.9 Dorsalgia, unspecified
0.734 0.266 0.000
M47 Spondylosis
0.733 0.267 0.000
M54.2 Cervicalgia
0.733 0.267 0.000
S32 Fracture of lumbar spine and pelvis
0.733 0.267 0.000
O72.1 Other immediate postpartum haemorrhage
0.731 0.269 0.000
K12 Stomatitis and related lesions
0.731 0.269 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.731 0.269 0.000
T40.2 Other opioids
0.730 0.269 0.000
O85-O92 Complications predominantly related to the puerperium
0.728 0.272 0.000
K05 Gingivitis and periodontal diseases
0.728 0.272 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.728 0.272 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.727 0.273 0.000
K90-K93 Other diseases of the digestive system
0.727 0.273 0.000
T86 Failure and rejection of transplanted organs and tissues
0.726 0.274 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.726 0.274 0.000
M72 Fibroblastic disorders
0.726 0.274 0.000
O47.9 False labour, unspecified
0.725 0.275 0.000
W21 Striking against or struck by sports equipment
0.725 0.275 0.000
F31 Bipolar affective disorder
0.725 0.275 0.000
B15-B19 Viral hepatitis
0.723 0.277 0.000
O80-O84 Delivery
0.722 0.278 0.000
L20-L30 Dermatitis and eczema
0.722 0.278 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.720 0.280 0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)
0.719 0.281 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.719 0.281 0.000
W20 Struck by thrown, projected or falling object
0.719 0.281 0.000
O34.1 Maternal care for tumour of corpus uteri
0.718 0.282 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.716 0.284 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.716 0.284 0.000
K90 Intestinal malabsorption
0.716 0.284 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.716 0.284 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.715 0.285 0.000
Y35-Y36 Legal intervention and operations of war
0.715 0.285 0.000
Y10-Y34 Event of undetermined intent
0.715 0.285 0.000
Y00-Y09 Assault
0.715 0.285 0.000
X85-X99 Assault
0.715 0.285 0.000
X50-X57 Overexertion, travel and privation
0.715 0.285 0.000
X30-X39 Exposure to forces of nature
0.715 0.285 0.000
X20-X29 Contact with venomous animals and plants
0.715 0.285 0.000
X10-X19 Contact with heat and hot substances
0.715 0.285 0.000
X00-X09 Exposure to smoke, fire and flames
0.715 0.285 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.715 0.285 0.000
W75-W84 Other accidental threats to breathing
0.715 0.285 0.000
W65-W74 Accidental drowning and submersion
0.715 0.285 0.000
W50-W64 Exposure to animate mechanical forces
0.715 0.285 0.000
V98-V99 Other and unspecified transport accidents
0.715 0.285 0.000
V95-V97 Air and space transport accidents
0.715 0.285 0.000
V90-V94 Water transport accidents
0.715 0.285 0.000
V70-V79 Bus occupant injured in transport accident
0.715 0.285 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.715 0.285 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.715 0.285 0.000
V40-V49 Car occupant injured in transport accident
0.715 0.285 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.715 0.285 0.000
V01-V09 Pedestrian injured in transport accident
0.715 0.285 0.000
M10.94 Gout, unspecified (Hand)
0.715 0.285 0.000
K04.7 Periapical abscess without sinus
0.714 0.286 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.714 0.286 0.000
I23 Certain current complications following acute myocardial infarction
0.714 0.286 0.000
O74 Complications of anaesthesia during labour and delivery
0.713 0.287 0.000
O71 Other obstetric trauma
0.713 0.287 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.713 0.287 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.713 0.287 0.000
O60 Preterm delivery
0.713 0.287 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.712 0.288 0.000
M91-M94 Chondropathies
0.712 0.288 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.711 0.289 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.711 0.289 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.711 0.289 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.711 0.289 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.711 0.289 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.711 0.289 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.711 0.289 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.711 0.289 0.000
T36 Poisoning by systemic antibiotics
0.711 0.289 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.711 0.289 0.000
T92 Sequelae of injuries of upper limb
0.710 0.290 0.000
T91 Sequelae of injuries of neck and trunk
0.709 0.291 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.709 0.291 0.000
O45 Premature separation of placenta [abruptio placentae]
0.708 0.292 0.000
O44 Placenta praevia
0.708 0.292 0.000
O33 Maternal care for known or suspected disproportion
0.708 0.292 0.000
O31 Complications specific to multiple gestation
0.708 0.292 0.000
V10-V19 Pedal cyclist injured in transport accident
0.707 0.293 0.000
O30 Multiple gestation
0.707 0.293 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.707 0.293 0.000
M75.8 Other shoulder lesions
0.706 0.294 0.000
Z35 Supervision of high-risk pregnancy
0.706 0.294 0.000
I10 Essential (primary) hypertension
0.706 0.294 0.000
M71 Other bursopathies
0.705 0.294 0.000
M14.6 Neuropathic arthropathy
0.705 0.295 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.704 0.296 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.704 0.296 0.000
O43.8 Other placental disorders
0.704 0.296 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.704 0.296 0.000
S50-S59 Injuries to the elbow and forearm
0.703 0.297 0.000
S20 Superficial injury of thorax
0.702 0.297 0.000
Y57 Other and unspecified drugs and medicaments
0.702 0.298 0.000
Y59 Other and unspecified vaccines and biological substances
0.701 0.299 0.000
Y58 Bacterial vaccines
0.701 0.299 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.701 0.299 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.701 0.299 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.701 0.299 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.701 0.299 0.000
Y48 Anaesthetics and therapeutic gases
0.701 0.299 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.701 0.299 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.701 0.299 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.701 0.299 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.700 0.300 0.000
I77.5 Necrosis of artery
0.700 0.300 0.000
I77.4 Coeliac artery compression syndrome
0.700 0.300 0.000
I77.3 Arterial fibromuscular dysplasia
0.700 0.300 0.000
I77.2 Rupture of artery
0.700 0.300 0.000
W29 Contact with other powered hand tools and household machinery
0.699 0.301 0.000
I73.8 Other specified peripheral vascular diseases
0.699 0.301 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.699 0.301 0.000
Y45.1 Salicylates
0.698 0.302 0.000
M85 Other disorders of bone density and structure
0.698 0.302 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.697 0.303 0.000
M49 Spondylopathies in diseases classified elsewhere
0.696 0.304 0.000
O47.0 False labour before 37 completed weeks of gestation
0.695 0.305 0.000
Y43 Primarily systemic agents
0.695 0.305 0.000
Z43 Attention to artificial openings
0.693 0.307 0.000
I70 Atherosclerosis
0.692 0.308 0.000
T43.9 Psychotropic drug, unspecified
0.692 0.308 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.692 0.308 0.000
T43.6 Psychostimulants with abuse potential
0.692 0.308 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.692 0.308 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.692 0.308 0.000
I25.6 Silent myocardial ischaemia
0.692 0.308 0.000
I25.4 Coronary artery aneurysm
0.692 0.308 0.000
I25.3 Aneurysm of heart
0.692 0.308 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.692 0.308 0.000
I67.1 Cerebral aneurysm, nonruptured
0.690 0.309 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.689 0.311 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.689 0.311 0.000
M12 Other specific arthropathies
0.688 0.312 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.688 0.312 0.000
M08 Juvenile arthritis
0.688 0.312 0.000
M23 Internal derangement of knee
0.688 0.312 0.000
K90.0 Coeliac disease
0.687 0.313 0.000
Z50 Care involving use of rehabilitation procedures
0.686 0.314 0.000
Z75 Problems related to medical facilities and other health care
0.683 0.317 0.000
T90 Sequelae of injuries of head
0.683 0.317 0.000
I12 Hypertensive renal disease
0.682 0.317 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.682 0.318 0.000
M66 Spontaneous rupture of synovium and tendon
0.682 0.318 0.000
O41 Other disorders of amniotic fluid and membranes
0.681 0.319 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.680 0.319 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.680 0.320 0.000
S27 Injury of other and unspecified intrathoracic organs
0.680 0.320 0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.678 0.322 0.000
Y45.8 Other analgesics and antipyretics
0.678 0.322 0.000
Y45.5 4-Aminophenol derivatives
0.678 0.322 0.000
Y45.4 Antirheumatics
0.678 0.322 0.000
Y45.2 Propionic acid derivatives
0.678 0.322 0.000
M00 Pyogenic arthritis
0.677 0.323 0.000
K70-K77 Diseases of liver
0.677 0.323 0.000
M75.2 Bicipital tendinitis
0.676 0.324 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.675 0.325 0.000
L27 Dermatitis due to substances taken internally
0.675 0.325 0.000
M10.97 Gout, unspecified (Ankle and foot)
0.675 0.325 0.000
O63.2 Delayed delivery of second twin, triplet, etc.
0.675 0.325 0.000
V20-V29 Motorcycle rider injured in transport accident
0.674 0.326 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.672 0.328 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.672 0.328 0.000
K09 Cysts of oral region, not elsewhere classified
0.672 0.328 0.000
M86 Osteomyelitis
0.671 0.328 0.000
O66 Other obstructed labour
0.671 0.329 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.670 0.330 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.670 0.330 0.000
L40-L45 Papulosquamous disorders
0.670 0.330 0.000
M80 Osteoporosis with pathological fracture
0.669 0.331 0.000
W22 Striking against or struck by other objects
0.669 0.331 0.000
F33 Recurrent depressive disorder
0.668 0.332 0.000
S70-S79 Injuries to the hip and thigh
0.666 0.333 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.666 0.334 0.000
F32.0 Mild depressive episode
0.666 0.334 0.000
K04.6 Periapical abscess with sinus
0.666 0.334 0.000
M65.8 Other synovitis and tenosynovitis
0.665 0.335 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.665 0.335 0.000
M65.2 Calcific tendinitis
0.665 0.335 0.000
M65.1 Other infective (teno)synovitis
0.665 0.335 0.000
M65.0 Abscess of tendon sheath
0.665 0.335 0.000
Z35.5 Supervision of elderly primigravida
0.665 0.335 0.000
Chapter VIII Diseases of the ear and mastoid process
0.664 0.336 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.664 0.336 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.664 0.336 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.664 0.336 0.000
T82.3 Mechanical complication of other vascular grafts
0.664 0.336 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.664 0.336 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.664 0.336 0.000
Z34 Supervision of normal pregnancy
0.664 0.336 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.663 0.337 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.663 0.337 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.663 0.337 0.000
K04.0 Pulpitis
0.662 0.338 0.000
I74 Arterial embolism and thrombosis
0.660 0.340 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.660 0.340 0.000
S91 Open wound of ankle and foot
0.659 0.340 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.659 0.341 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.658 0.341 0.000
M89 Other disorders of bone
0.658 0.342 0.000
Z39 Postpartum care and examination
0.658 0.342 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.658 0.342 0.000
T93.1 Sequelae of fracture of femur
0.658 0.342 0.000
T51 Toxic effect of alcohol
0.658 0.342 0.000
M65.39 Trigger finger-Site unspec
0.658 0.342 0.000
M65.38 Trigger finger-Other
0.658 0.342 0.000
M65.37 Trigger finger-Ankle/foot
0.658 0.342 0.000
M65.36 Trigger finger-Lower leg
0.658 0.342 0.000
M65.35 Trigger finger-Pelvic/thigh
0.658 0.342 0.000
M65.33 Trigger finger-Forearm
0.658 0.342 0.000
M65.32 Trigger finger-Upper arm
0.658 0.342 0.000
M65.31 Trigger finger-Shldr region
0.658 0.342 0.000
M65.30 Trigger finger-Mult sites
0.658 0.342 0.000
T98 Sequelae of other and unspecified effects of external causes
0.656 0.344 0.000
T95 Sequelae of burns, corrosions and frostbite
0.656 0.344 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.656 0.344 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.656 0.344 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.656 0.344 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.656 0.344 0.000
K90.9 Intestinal malabsorption, unspecified
0.656 0.344 0.000
S12 Fracture of neck
0.655 0.345 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.655 0.345 0.000
T85.2 Mechanical complication of intraocular lens
0.655 0.345 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.655 0.345 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.655 0.345 0.000
W44 Foreign body entering into or through eye or natural orifice
0.655 0.345 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.655 0.345 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.654 0.346 0.000
M46.8 Other specified inflammatory spondylopathies
0.653 0.347 0.000
M46.5 Other infective spondylopathies
0.653 0.347 0.000
M46.4 Discitis, unspecified
0.653 0.347 0.000
M46.3 Infection of intervertebral disk (pyogenic)
0.653 0.347 0.000
M46.2 Osteomyelitis of vertebra
0.653 0.347 0.000
M46.1 Sacro-iliitis, not elsewhere classified
0.653 0.347 0.000
M46.0 Spinal enthesopathy
0.653 0.347 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.653 0.347 0.000
S26 Injury of heart
0.653 0.347 0.000
S25 Injury of blood vessels of thorax
0.653 0.347 0.000
S24 Injury of nerves and spinal cord at thorax level
0.653 0.347 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.653 0.347 0.000
S21 Open wound of thorax
0.653 0.347 0.000
T45.0 Antiallergic and antiemetic drugs
0.652 0.348 0.000
M83 Adult osteomalacia
0.652 0.348 0.000
M82 Osteoporosis in diseases classified elsewhere
0.652 0.348 0.000
M54.16 Radiculopathy (Lumbar region)
0.652 0.348 0.000
M75.3 Calcific tendinitis of shoulder
0.651 0.349 0.000
S22.0 Fracture of thoracic vertebra
0.651 0.349 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.651 0.349 0.000
M06 Other rheumatoid arthritis
0.650 0.350 0.000
K04.8 Radicular cyst
0.650 0.350 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.650 0.350 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.649 0.350 0.000
M41 Scoliosis
0.648 0.352 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.648 0.352 0.000
I62 Other nontraumatic intracranial haemorrhage
0.647 0.353 0.000
M43.1 Spondylolisthesis
0.647 0.353 0.000
W25 Contact with sharp glass
0.647 0.353 0.000
B99-B99 Other infectious diseases
0.646 0.354 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.646 0.354 0.000
B65-B83 Helminthiases
0.646 0.354 0.000
B50-B64 Protozoal diseases
0.646 0.354 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.646 0.354 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.646 0.354 0.000
A75-A79 Rickettsioses
0.646 0.354 0.000
A70-A74 Other diseases caused by chlamydiae
0.646 0.354 0.000
A65-A69 Other spirochaetal diseases
0.646 0.354 0.000
A20-A28 Certain zoonotic bacterial diseases
0.646 0.354 0.000
A15-A19 Tuberculosis
0.646 0.354 0.000
M77.9 Enthesopathy, unspecified
0.646 0.354 0.000
I11 Hypertensive heart disease
0.646 0.354 0.000
M81.9 Osteoporosis, unspecified
0.645 0.355 0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)
0.643 0.357 0.000
I61 Intracerebral haemorrhage
0.643 0.357 0.000
K07 Dentofacial anomalies [including malocclusion]
0.642 0.357 0.000
W49 Exposure to other and unspecified inanimate mechanical forces
0.641 0.359 0.000
W46 Contact with hypodermic needle
0.641 0.359 0.000
W45 Foreign body or object entering through skin
0.641 0.359 0.000
W43 Exposure to vibration
0.641 0.359 0.000
W42 Exposure to noise
0.641 0.359 0.000
W41 Exposure to high-pressure jet
0.641 0.359 0.000
W40 Explosion of other materials
0.641 0.359 0.000
W39 Discharge of firework
0.641 0.359 0.000
W38 Explosion and rupture of other specified pressurised devices
0.641 0.359 0.000
W37 Explosion and rupture of pressurised tyre, pipe or hose
0.641 0.359 0.000
W36 Explosion and rupture of gas cylinder
0.641 0.359 0.000
W35 Explosion and rupture of boiler
0.641 0.359 0.000
W34 Discharge from other and unspecified firearms
0.641 0.359 0.000
W33 Rifle, shotgun and larger firearm discharge
0.641 0.359 0.000
W32 Handgun discharge
0.641 0.359 0.000
W31 Contact with other and unspecified machinery
0.641 0.359 0.000
W30 Contact with agricultural machinery
0.641 0.359 0.000
W28 Contact with powered lawn mower
0.641 0.359 0.000
W27 Contact with nonpowered hand tool
0.641 0.359 0.000
W26 Contact with knife, sword or dagger
0.641 0.359 0.000
W24 Contact with lifting and transmission devices, not elsewhere classified
0.641 0.359 0.000
W23 Caught, crushed, jammed or pinched in or between objects
0.641 0.359 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.640 0.360 0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium
0.639 0.360 0.000
Y40 Systemic antibiotics
0.639 0.361 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.638 0.361 0.000
M10.4 Other secondary gout
0.638 0.361 0.000
M10.3 Gout due to impairment of renal function
0.638 0.361 0.000
M10.2 Drug-induced gout
0.638 0.361 0.000
M10.1 Lead-induced gout
0.638 0.361 0.000
M10.0 Idiopathic gout
0.638 0.361 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.638 0.362 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.638 0.362 0.000
I05-I09 Chronic rheumatic heart diseases
0.638 0.362 0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified
0.637 0.363 0.000
S90 Superficial injury of ankle and foot
0.637 0.363 0.000
F80-F89 Disorders of psychological development
0.636 0.364 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.636 0.364 0.000
Z50.1 Other physical therapy
0.636 0.364 0.000
O43.9 Placental disorder, unspecified
0.636 0.364 0.000
O43.2 Morbidly adherent placenta
0.636 0.364 0.000
O43.0 Placental transfusion syndromes
0.636 0.364 0.000
M54.4 Lumbago with sciatica
0.636 0.364 0.000
L60-L75 Disorders of skin appendages
0.635 0.365 0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress
0.635 0.365 0.000
K04.5 Chronic apical periodontitis
0.635 0.365 0.000
M31 Other necrotising vasculopathies
0.634 0.366 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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