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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs114653669
log Bayes Factor = 13.949
Chromosome 1   position 222,548,555  (GRCh37) Explore rs114653669 on Ensembl!
Variant rs114653669 is part of Cluster X0145

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.999 0.001 0.000
K40-K46 Hernia
0.996 0.004 0.000
I21 Acute myocardial infarction
0.996 0.004 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.993 0.007 0.000
I20 Angina pectoris
0.992 0.008 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.986 0.014 0.000
M70-M79 Other soft tissue disorders
0.985 0.015 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.983 0.017 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.982 0.018 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.981 0.019 0.000
M79.8 Other specified soft tissue disorders
0.977 0.023 0.000
Chapter VI Diseases of the nervous system
0.974 0.026 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.973 0.027 0.000
I20.9 Angina pectoris, unspecified
0.972 0.028 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.971 0.029 0.000
M05-M14 Inflammatory polyarthropathies
0.970 0.030 0.000
Chapter V Mental and behavioural disorders
0.966 0.034 0.000
R20 Disturbances of skin sensation
0.963 0.037 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.959 0.041 0.000
K70-K77 Diseases of liver
0.959 0.041 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.956 0.044 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.955 0.045 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.954 0.046 0.000
Chapter X Diseases of the respiratory system
0.953 0.047 0.000
K44 Diaphragmatic hernia
0.952 0.048 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.951 0.049 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.949 0.051 0.000
K43 Ventral hernia
0.944 0.056 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.940 0.060 0.000
Chapter XX External causes of morbidity and mortality
0.937 0.063 0.000
M79.6 Pain in limb
0.927 0.073 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.926 0.074 0.000
K44.9 Diaphragmatic hernia without obstruction or gangrene
0.920 0.080 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.918 0.082 0.000
M06 Other rheumatoid arthritis
0.914 0.086 0.000
I25 Chronic ischaemic heart disease
0.910 0.090 0.000
I20.0 Unstable angina
0.909 0.091 0.000
K42 Umbilical hernia
0.909 0.091 0.000
G40-G47 Episodic and paroxysmal disorders
0.908 0.092 0.000
I80 Phlebitis and thrombophlebitis
0.903 0.097 0.000
R94 Abnormal results of function studies
0.896 0.104 0.000
K08 Other disorders of teeth and supporting structures
0.896 0.104 0.000
Chapter XXI Factors influencing health status and contact with health services
0.895 0.105 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.889 0.111 0.000
K43.9 Ventral hernia without obstruction or gangrene
0.885 0.115 0.000
F30-F39 Mood [affective] disorders
0.880 0.120 0.000
S60-S69 Injuries to the wrist and hand
0.876 0.124 0.000
Chapter VIII Diseases of the ear and mastoid process
0.875 0.125 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.874 0.126 0.000
Chapter XIV Diseases of the genitourinary system
0.873 0.127 0.000
N20-N23 Urolithiasis
0.863 0.137 0.000
K90-K93 Other diseases of the digestive system
0.859 0.141 0.000
N20 Calculus of kidney and ureter
0.858 0.142 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.857 0.143 0.000
I22 Subsequent myocardial infarction
0.855 0.145 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.854 0.146 0.000
J90-J94 Other diseases of pleura
0.853 0.147 0.000
R30-R39 Symptoms and signs involving the urinary system
0.853 0.147 0.000
M06.9 Rheumatoid arthritis, unspecified
0.852 0.148 0.000
G90-G99 Other disorders of the nervous system
0.852 0.148 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.849 0.151 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.846 0.154 0.000
I85 Oesophageal varices
0.845 0.155 0.000
G40 Epilepsy
0.843 0.157 0.000
L89 Decubitus ulcer
0.841 0.159 0.000
J40-J47 Chronic lower respiratory diseases
0.839 0.161 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.839 0.161 0.000
N17-N19 Renal failure
0.837 0.163 0.000
K08.3 Retained dental root
0.837 0.163 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.837 0.163 0.000
M40-M43 Deforming dorsopathies
0.836 0.164 0.000
M79.69 Pain in limb (Site unspecified)
0.833 0.167 0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.832 0.168 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.829 0.171 0.000
K50-K52 Noninfective enteritis and colitis
0.828 0.172 0.000
R25 Abnormal involuntary movements
0.828 0.172 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.825 0.175 0.000
K65-K67 Diseases of peritoneum
0.824 0.176 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.823 0.177 0.000
K76 Other diseases of liver
0.823 0.177 0.000
R26 Abnormalities of gait and mobility
0.820 0.180 0.000
J09-J18 Influenza and pneumonia
0.820 0.180 0.000
N20.0 Calculus of kidney
0.819 0.181 0.000
R94.5 Abnormal results of liver function studies
0.816 0.184 0.000
Chapter XXII Codes for special purposes
0.814 0.186 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.813 0.187 0.000
I05-I09 Chronic rheumatic heart diseases
0.813 0.187 0.000
M13 Other arthritis
0.812 0.188 0.000
M10 Gout
0.811 0.189 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.811 0.189 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.808 0.192 0.000
K42.0 Umbilical hernia with obstruction, without gangrene
0.806 0.194 0.000
K12 Stomatitis and related lesions
0.806 0.194 0.000
K11 Diseases of salivary glands
0.805 0.195 0.000
R42 Dizziness and giddiness
0.802 0.198 0.000
J90 Pleural effusion, not elsewhere classified
0.802 0.198 0.000
K75 Other inflammatory liver diseases
0.802 0.198 0.000
F31 Bipolar affective disorder
0.802 0.198 0.000
T66-T78 Other and unspecified effects of external causes
0.801 0.199 0.000
H65-H75 Diseases of middle ear and mastoid
0.801 0.199 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.800 0.200 0.000
J43 Emphysema
0.799 0.200 0.000
I25.2 Old myocardial infarction
0.798 0.202 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.795 0.205 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.795 0.205 0.000
K45 Other abdominal hernia
0.793 0.207 0.000
N20.1 Calculus of ureter
0.793 0.207 0.000
Z60 Problems related to social environment
0.792 0.208 0.000
S61 Open wound of wrist and hand
0.791 0.209 0.000
K22 Other diseases of oesophagus
0.791 0.209 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.791 0.209 0.000
M65-M68 Disorders of synovium and tendon
0.790 0.210 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.788 0.212 0.000
L82 Seborrhoeic keratosis
0.788 0.212 0.000
K74 Fibrosis and cirrhosis of liver
0.785 0.215 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.785 0.215 0.000
K72 Hepatic failure, not elsewhere classified
0.784 0.216 0.000
M79.66 Pain in limb (Lower leg)
0.783 0.217 0.000
G40.9 Epilepsy, unspecified
0.783 0.217 0.000
G93 Other disorders of brain
0.782 0.218 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.781 0.219 0.000
R21 Rash and other nonspecific skin eruption
0.781 0.219 0.000
M91-M94 Chondropathies
0.779 0.221 0.000
H72 Perforation of tympanic membrane
0.779 0.221 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.778 0.222 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.778 0.222 0.000
I85.9 Oesophageal varices without bleeding
0.777 0.223 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.777 0.223 0.000
M79.89 Other specified soft tissue disorders (Site unspecified)
0.775 0.224 0.000
K43.0 Ventral hernia with obstruction, without gangrene
0.772 0.228 0.000
R40 Somnolence, stupor and coma
0.772 0.228 0.000
J43.9 Emphysema, unspecified
0.771 0.229 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.769 0.231 0.000
K25 Gastric ulcer
0.768 0.232 0.000
N18 Chronic renal failure
0.768 0.232 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.767 0.233 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.766 0.234 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.765 0.235 0.000
Z29 Need for other prophylactic measures
0.765 0.235 0.000
G43 Migraine
0.764 0.236 0.000
Z74 Problems related to care-provider dependency
0.763 0.237 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.763 0.237 0.000
K22.1 Ulcer of oesophagus
0.763 0.237 0.000
J60-J70 Lung diseases due to external agents
0.762 0.238 0.000
R45 Symptoms and signs involving emotional state
0.762 0.238 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.762 0.238 0.000
H60-H62 Diseases of external ear
0.761 0.239 0.000
R94.3 Abnormal results of cardiovascular function studies
0.761 0.239 0.000
K10 Other diseases of jaws
0.761 0.239 0.000
I25.5 Ischaemic cardiomyopathy
0.761 0.239 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.759 0.241 0.000
R30 Pain associated with micturition
0.759 0.241 0.000
M79.63 Pain in limb (Forearm)
0.756 0.244 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.756 0.244 0.000
K65 Peritonitis
0.754 0.246 0.000
Z60.2 Living alone
0.754 0.246 0.000
K42.9 Umbilical hernia without obstruction or gangrene
0.753 0.247 0.000
L83 Acanthosis nigricans
0.751 0.249 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.750 0.250 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.750 0.250 0.000
N17 Acute renal failure
0.750 0.250 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.749 0.251 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.749 0.251 0.000
M06.0 Seronegative rheumatoid arthritis
0.749 0.251 0.000
M00-M03 Infectious arthropathies
0.748 0.252 0.000
G81 Hemiplegia
0.747 0.253 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.747 0.253 0.000
M77 Other enthesopathies
0.746 0.254 0.000
N20.2 Calculus of kidney with calculus of ureter
0.746 0.254 0.000
K07 Dentofacial anomalies [including malocclusion]
0.745 0.255 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.745 0.255 0.000
I86 Varicose veins of other sites
0.743 0.257 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.742 0.258 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.741 0.259 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.741 0.259 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.740 0.260 0.000
R31 Unspecified haematuria
0.739 0.261 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.737 0.263 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.736 0.264 0.000
S20-S29 Injuries to the thorax
0.736 0.264 0.000
M80-M85 Disorders of bone density and structure
0.735 0.265 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.735 0.265 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.734 0.265 0.000
T79-T79 Certain early complications of trauma
0.734 0.266 0.000
I20.1 Angina pectoris with documented spasm
0.731 0.268 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.731 0.269 0.000
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.731 0.269 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.731 0.269 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.731 0.269 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.731 0.269 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.728 0.272 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.728 0.272 0.000
K13 Other diseases of lip and oral mucosa
0.728 0.272 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.727 0.273 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.726 0.274 0.000
N18.3 Chronic kidney disease, stage 3
0.726 0.274 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.725 0.275 0.000
F31.9 Bipolar affective disorder, unspecified
0.725 0.275 0.000
S90-S99 Injuries to the ankle and foot
0.724 0.276 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.723 0.277 0.000
I87 Other disorders of veins
0.723 0.277 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.723 0.277 0.000
V20-V29 Motorcycle rider injured in transport accident
0.722 0.278 0.000
R35 Polyuria
0.721 0.279 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.719 0.281 0.000
G20-G26 Extrapyramidal and movement disorders
0.718 0.282 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.718 0.282 0.000
M11 Other crystal arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
M79.67 Pain in limb (Ankle and foot)
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.716 0.283 0.000
S70-S79 Injuries to the hip and thigh
0.715 0.285 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.714 0.286 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.714 0.286 0.000
K05 Gingivitis and periodontal diseases
0.714 0.286 0.000
K76.6 Portal hypertension
0.713 0.287 0.000
M60-M63 Disorders of muscles
0.712 0.288 0.000
I20.8 Other forms of angina pectoris
0.711 0.289 0.000
J46 Status asthmaticus
0.711 0.289 0.000
K91.4 Colostomy and enterostomy malfunction
0.710 0.290 0.000
K70 Alcoholic liver disease
0.710 0.290 0.000
L81 Other disorders of pigmentation
0.709 0.291 0.000
M41 Scoliosis
0.708 0.292 0.000
G44 Other headache syndromes
0.707 0.293 0.000
M05 Seropositive rheumatoid arthritis
0.707 0.293 0.000
R73 Elevated blood glucose level
0.707 0.293 0.000
L98.4 Chronic ulcer of skin, not elsewhere classified
0.707 0.293 0.000
K08.9 Disorder of teeth and supporting structures, unspecified
0.707 0.293 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.706 0.294 0.000
M76 Enthesopathies of lower limb, excluding foot
0.706 0.294 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.706 0.294 0.000
R25.1 Tremor, unspecified
0.706 0.294 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.706 0.294 0.000
M79.9 Soft tissue disorder, unspecified
0.705 0.295 0.000
M79.7 Fibromyalgia
0.705 0.295 0.000
M79.5 Residual foreign body in soft tissue
0.705 0.295 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.705 0.295 0.000
M79.3 Panniculitis, unspecified
0.705 0.295 0.000
M79.2 Neuralgia and neuritis, unspecified
0.705 0.295 0.000
M79.1 Myalgia
0.705 0.295 0.000
W20-W49 Exposure to inanimate mechanical forces
0.705 0.295 0.000
M71 Other bursopathies
0.705 0.295 0.000
F60-F69 Disorders of adult personality and behaviour
0.704 0.296 0.000
T33-T35 Frostbite
0.704 0.296 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.704 0.296 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.704 0.296 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.704 0.296 0.000
T00-T07 Injuries involving multiple body regions
0.704 0.296 0.000
S10-S19 Injuries to the neck
0.704 0.296 0.000
R23 Other skin changes
0.703 0.297 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.703 0.297 0.000
I08 Multiple valve diseases
0.701 0.299 0.000
M79.88 Other specified soft tissue disorders (Other)
0.700 0.300 0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)
0.700 0.300 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.700 0.300 0.000
M79.83 Other specified soft tissue disorders (Forearm)
0.700 0.300 0.000
M79.82 Other specified soft tissue disorders (Upper arm)
0.700 0.300 0.000
M79.81 Other specified soft tissue disorders (Shoulder region)
0.700 0.300 0.000
M79.80 Other specified soft tissue disorders (Multiple sites)
0.700 0.300 0.000
Z22 Carrier of infectious disease
0.699 0.301 0.000
M13.9 Arthritis, unspecified
0.699 0.301 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.699 0.301 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.699 0.301 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.699 0.301 0.000
K01 Embedded and impacted teeth
0.698 0.301 0.000
M86-M90 Other osteopathies
0.698 0.302 0.000
Y48 Anaesthetics and therapeutic gases
0.698 0.302 0.000
L10-L14 Bullous disorders
0.698 0.302 0.000
J00-J06 Acute upper respiratory infections
0.697 0.303 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.697 0.303 0.000
M10.9 Gout, unspecified
0.697 0.303 0.000
M79.64 Pain in limb (Hand)
0.696 0.304 0.000
M14 Arthropathies in other diseases classified elsewhere
0.695 0.304 0.000
M12 Other specific arthropathies
0.695 0.304 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.695 0.304 0.000
M08 Juvenile arthritis
0.695 0.304 0.000
Z74.0 Reduced mobility
0.695 0.305 0.000
M07 Psoriatic and enteropathic arthropathies
0.693 0.307 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.692 0.307 0.000
F80-F89 Disorders of psychological development
0.692 0.307 0.000
F70-F79 Mental retardation
0.692 0.307 0.000
K50 Crohn's disease [regional enteritis]
0.692 0.308 0.000
R30.0 Dysuria
0.691 0.309 0.000
K41 Femoral hernia
0.691 0.309 0.000
K12.2 Cellulitis and abscess of mouth
0.690 0.310 0.000
S61.0 Open wound of finger(s) without damage to nail
0.690 0.310 0.000
R20.3 Hyperaesthesia
0.690 0.310 0.000
R20.1 Hypoaesthesia of skin
0.690 0.310 0.000
R20.0 Anaesthesia of skin
0.690 0.310 0.000
G70-G73 Diseases of myoneural junction and muscle
0.689 0.311 0.000
M79.0 Rheumatism, unspecified
0.688 0.312 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.688 0.312 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.688 0.312 0.000
L94 Other localised connective tissue disorders
0.688 0.312 0.000
L93 Lupus erythematosus
0.688 0.312 0.000
L87 Transepidermal elimination disorders
0.688 0.312 0.000
L88 Pyoderma gangrenosum
0.688 0.312 0.000
L86 Keratoderma in diseases classified elsewhere
0.688 0.312 0.000
L80 Vitiligo
0.688 0.312 0.000
N17.9 Acute renal failure, unspecified
0.688 0.312 0.000
K77 Liver disorders in diseases classified elsewhere
0.687 0.313 0.000
K73 Chronic hepatitis, not elsewhere classified
0.687 0.313 0.000
K71 Toxic liver disease
0.687 0.313 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.685 0.315 0.000
L03 Cellulitis
0.685 0.315 0.000
K09 Cysts of oral region, not elsewhere classified
0.684 0.316 0.000
K03 Other diseases of hard tissues of teeth
0.684 0.316 0.000
K00 Disorders of tooth development and eruption
0.684 0.316 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.684 0.316 0.000
L91 Hypertrophic disorders of skin
0.683 0.317 0.000
K44.1 Diaphragmatic hernia with gangrene
0.682 0.317 0.000
K44.0 Diaphragmatic hernia with obstruction, without gangrene
0.682 0.317 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.682 0.318 0.000
Z71.8 Other specified counselling
0.681 0.319 0.000
L60-L75 Disorders of skin appendages
0.680 0.320 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.678 0.322 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.678 0.322 0.000
F99-F99 Unspecified mental disorder
0.677 0.323 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.677 0.323 0.000
K43.7 Other and unspecified ventral hernia with gangrene
0.676 0.323 0.000
K43.6 Other and unspecified ventral hernia with obstruction, without gangrene
0.676 0.323 0.000
K43.5 Parastomal hernia without obstruction or gangrene
0.676 0.323 0.000
K43.4 Parastomal hernia with gangrene
0.676 0.323 0.000
K43.3 Parastomal hernia with obstruction, without gangrene
0.676 0.323 0.000
K43.2 Incisional hernia without obstruction or gangrene
0.676 0.323 0.000
K43.1 Ventral hernia with gangrene
0.676 0.323 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.676 0.324 0.000
S80-S89 Injuries to the knee and lower leg
0.676 0.324 0.000
K51 Ulcerative colitis
0.676 0.324 0.000
J18 Pneumonia, organism unspecified
0.675 0.325 0.000
L89.9 Decubitus ulcer and pressure area, unspecified
0.675 0.325 0.000
I88 Nonspecific lymphadenitis
0.674 0.326 0.000
I81 Portal vein thrombosis
0.674 0.326 0.000
I21.9 Acute myocardial infarction, unspecified
0.674 0.326 0.000
L89.0 Stage I decubitus ulcer and pressure area
0.673 0.327 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.672 0.328 0.000
Y35-Y36 Legal intervention and operations of war
0.672 0.328 0.000
Y10-Y34 Event of undetermined intent
0.672 0.328 0.000
Y00-Y09 Assault
0.672 0.328 0.000
X85-X99 Assault
0.672 0.328 0.000
X50-X57 Overexertion, travel and privation
0.672 0.328 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.672 0.328 0.000
X30-X39 Exposure to forces of nature
0.672 0.328 0.000
X20-X29 Contact with venomous animals and plants
0.672 0.328 0.000
X10-X19 Contact with heat and hot substances
0.672 0.328 0.000
X00-X09 Exposure to smoke, fire and flames
0.672 0.328 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.672 0.328 0.000
W75-W84 Other accidental threats to breathing
0.672 0.328 0.000
W65-W74 Accidental drowning and submersion
0.672 0.328 0.000
W50-W64 Exposure to animate mechanical forces
0.672 0.328 0.000
V98-V99 Other and unspecified transport accidents
0.672 0.328 0.000
V95-V97 Air and space transport accidents
0.672 0.328 0.000
V90-V94 Water transport accidents
0.672 0.328 0.000
V80-V89 Other land transport accidents
0.672 0.328 0.000
V70-V79 Bus occupant injured in transport accident
0.672 0.328 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.672 0.328 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.672 0.328 0.000
V40-V49 Car occupant injured in transport accident
0.672 0.328 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.672 0.328 0.000
V01-V09 Pedestrian injured in transport accident
0.672 0.328 0.000
T68 Hypothermia
0.672 0.328 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.672 0.328 0.000
Z29.0 Isolation
0.672 0.328 0.000
S64 Injury of nerves at wrist and hand level
0.671 0.329 0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.671 0.329 0.000
G81.9 Hemiplegia, unspecified
0.671 0.329 0.000
M79.60 Pain in limb (Multiple sites)
0.670 0.330 0.000
R20.2 Paraesthesia of skin
0.669 0.331 0.000
K40 Inguinal hernia
0.668 0.332 0.000
L89.1 Stage II decubitus ulcer
0.667 0.333 0.000
F33 Recurrent depressive disorder
0.667 0.333 0.000
S62 Fracture at wrist and hand level
0.666 0.334 0.000
N20.9 Urinary calculus, unspecified
0.666 0.334 0.000
M79.68 Pain in limb (Other)
0.665 0.335 0.000
M79.61 Pain in limb (Shoulder region)
0.665 0.335 0.000
T93 Sequelae of injuries of lower limb
0.665 0.335 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.665 0.335 0.000
G30-G32 Other degenerative diseases of the nervous system
0.664 0.335 0.000
R27 Other lack of coordination
0.664 0.336 0.000
R46 Symptoms and signs involving appearance and behaviour
0.664 0.336 0.000
R43 Disturbances of smell and taste
0.664 0.336 0.000
I82 Other venous embolism and thrombosis
0.662 0.338 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.662 0.338 0.000
K46 Unspecified abdominal hernia
0.661 0.338 0.000
G43.9 Migraine, unspecified
0.661 0.339 0.000
R25.2 Cramp and spasm
0.661 0.339 0.000
R40.2 Coma, unspecified
0.660 0.340 0.000
K72.9 Hepatic failure, unspecified
0.659 0.341 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.659 0.341 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.659 0.341 0.000
G93.3 Postviral fatigue syndrome
0.658 0.342 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.658 0.342 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.658 0.342 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.658 0.342 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.658 0.342 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.658 0.342 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.658 0.342 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.658 0.342 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.658 0.342 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.658 0.342 0.000
T36 Poisoning by systemic antibiotics
0.658 0.342 0.000
Z63 Other problems related to primary support group, including family circumstances
0.657 0.342 0.000
M06.8 Other specified rheumatoid arthritis
0.656 0.344 0.000
M06.4 Inflammatory polyarthropathy
0.656 0.344 0.000
M06.3 Rheumatoid nodule
0.656 0.344 0.000
M06.2 Rheumatoid bursitis
0.656 0.344 0.000
M06.1 Adult-onset Still's disease
0.656 0.344 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.655 0.345 0.000
J42 Unspecified chronic bronchitis
0.654 0.345 0.000
R18 Ascites
0.655 0.345 0.000
K11.5 Sialolithiasis
0.654 0.346 0.000
F17.2 Dependence syndrome
0.654 0.346 0.000
F32 Depressive episode
0.653 0.347 0.000
K08.8 Other specified disorders of teeth and supporting structures
0.653 0.347 0.000
K75.8 Other specified inflammatory liver diseases
0.653 0.347 0.000
I25.6 Silent myocardial ischaemia
0.652 0.348 0.000
I25.4 Coronary artery aneurysm
0.652 0.348 0.000
I25.3 Aneurysm of heart
0.652 0.348 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.652 0.348 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.652 0.348 0.000
K42.1 Umbilical hernia with gangrene
0.652 0.348 0.000
S40-S49 Injuries to the shoulder and upper arm
0.651 0.348 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.651 0.349 0.000
G41 Status epilepticus
0.651 0.349 0.000
T43.2 Other and unspecified antidepressants
0.651 0.349 0.000
G35 Multiple sclerosis
0.651 0.349 0.000
K74.0 Hepatic fibrosis
0.649 0.351 0.000
K45.8 Other specified abdominal hernia without obstruction or gangrene
0.648 0.352 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.648 0.352 0.000
I80.8 Phlebitis and thrombophlebitis of other sites
0.648 0.352 0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.648 0.352 0.000
V10-V19 Pedal cyclist injured in transport accident
0.646 0.354 0.000
H60 Otitis externa
0.645 0.355 0.000
J91 Pleural effusion in conditions classified elsewhere
0.644 0.355 0.000
Z57 Occupational exposure to risk-factors
0.644 0.356 0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum
0.644 0.356 0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome
0.644 0.356 0.000
G83 Other paralytic syndromes
0.643 0.357 0.000
R94.8 Abnormal results of function studies of other organs and systems
0.642 0.357 0.000
R94.7 Abnormal results of other endocrine function studies
0.642 0.357 0.000
R94.6 Abnormal results of thyroid function studies
0.642 0.357 0.000
R94.4 Abnormal results of kidney function studies
0.642 0.357 0.000
R94.2 Abnormal results of pulmonary function studies
0.642 0.357 0.000
R94.1 Abnormal results of function studies of peripheral nervous system and special senses
0.642 0.357 0.000
R94.0 Abnormal results of function studies of central nervous system
0.642 0.357 0.000
K08.2 Atrophy of edentulous alveolar ridge
0.642 0.358 0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease
0.642 0.358 0.000
K08.0 Exfoliation of teeth due to systemic causes
0.642 0.358 0.000
K12.0 Recurrent oral aphthae
0.642 0.358 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.641 0.359 0.000
N00-N08 Glomerular diseases
0.640 0.360 0.000
Z29.1 Prophylactic immunotherapy
0.640 0.360 0.000
K22.7 Barrett's oesophagus
0.640 0.360 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.639 0.361 0.000
M72 Fibroblastic disorders
0.639 0.361 0.000
L50-L54 Urticaria and erythema
0.639 0.361 0.000
L08 Other local infections of skin and subcutaneous tissue
0.638 0.362 0.000
K65.0 Acute peritonitis
0.638 0.362 0.000
L98.7 Excessive and redundant skin and subcutaneous tissue
0.638 0.362 0.000
L98.6 Other infiltrative disorders of skin and subcutaneous tissue
0.638 0.362 0.000
L98.5 Mucinosis of skin
0.638 0.362 0.000
L98.3 Eosinophilic cellulitis [Wells]
0.638 0.362 0.000
L98.2 Febrile neutrophilic dermatosis [Sweet]
0.638 0.362 0.000
L98.1 Factitial dermatitis
0.638 0.362 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.635 0.364 0.000
X60-X84 Intentional self-harm
0.635 0.365 0.000
R45.1 Restlessness and agitation
0.635 0.365 0.000
G93.8 Other specified disorders of brain
0.634 0.366 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.634 0.366 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.633 0.366 0.000
K35-K38 Diseases of appendix
0.633 0.367 0.000
G96 Other disorders of central nervous system
0.633 0.367 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.632 0.368 0.000
J10 Influenza due to identified influenza virus
0.631 0.369 0.000
F38 Other mood [affective] disorders
0.631 0.369 0.000
F34 Persistent mood [affective] disorders
0.631 0.369 0.000
F30 Manic episode
0.631 0.369 0.000
F39 Unspecified mood [affective] disorder
0.631 0.369 0.000
K75.9 Inflammatory liver disease, unspecified
0.631 0.369 0.000
G82 Paraplegia and tetraplegia
0.630 0.370 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.630 0.370 0.000
M43 Other deforming dorsopathies
0.629 0.370 0.000
H72.0 Central perforation of tympanic membrane
0.629 0.371 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.628 0.372 0.000
S69 Other and unspecified injuries of wrist and hand
0.628 0.372 0.000
S67 Crushing injury of wrist and hand
0.628 0.372 0.000
S65 Injury of blood vessels at wrist and hand level
0.628 0.372 0.000
S60 Superficial injury of wrist and hand
0.628 0.372 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.627 0.373 0.000
M65 Synovitis and tenosynovitis
0.626 0.374 0.000
M94 Other disorders of cartilage
0.626 0.374 0.000
Z74.2 Need for assistance at home and no other household member able to render care
0.626 0.374 0.000
K82 Other diseases of gallbladder
0.624 0.376 0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs
0.624 0.376 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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