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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs114659777
log Bayes Factor = 10.4967
Chromosome 5   position 146,011,408  (GRCh37) Explore rs114659777 on Ensembl!
Variant rs114659777 is part of Cluster X0076

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.999 0.001 0.000
C34 Malignant neoplasm of bronchus and lung
0.998 0.002 0.000
C34.9 Bronchus or lung, unspecified
0.995 0.005 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.987 0.013 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.987 0.013 0.000
Chapter XX External causes of morbidity and mortality
0.985 0.015 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.985 0.015 0.000
O60-O75 Complications of labour and delivery
0.981 0.019 0.000
S50-S59 Injuries to the elbow and forearm
0.981 0.019 0.000
Chapter VIII Diseases of the ear and mastoid process
0.979 0.021 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.973 0.027 0.000
C15-C26 Malignant neoplasms of digestive organs
0.970 0.030 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.967 0.033 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.965 0.035 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.961 0.039 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.956 0.044 0.000
C79 Secondary malignant neoplasm of other sites
0.951 0.049 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.948 0.052 0.000
S52 Fracture of forearm
0.944 0.056 0.000
H65-H75 Diseases of middle ear and mastoid
0.942 0.058 0.000
D69 Purpura and other haemorrhagic conditions
0.942 0.058 0.000
Chapter I Certain infectious and parasitic diseases
0.941 0.059 0.000
O72 Postpartum haemorrhage
0.939 0.061 0.000
S60-S69 Injuries to the wrist and hand
0.933 0.067 0.000
T66-T78 Other and unspecified effects of external causes
0.932 0.068 0.000
E00-E07 Disorders of thyroid gland
0.932 0.068 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.921 0.079 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.917 0.083 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.917 0.083 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.911 0.089 0.000
C15 Malignant neoplasm of oesophagus
0.909 0.091 0.000
S70-S79 Injuries to the hip and thigh
0.904 0.096 0.000
C18 Malignant neoplasm of colon
0.903 0.097 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.896 0.104 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.896 0.104 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.893 0.107 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.893 0.107 0.000
C64-C68 Malignant neoplasms of urinary tract
0.892 0.108 0.000
S51 Open wound of forearm
0.891 0.109 0.000
O32.1 Maternal care for breech presentation
0.890 0.110 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.884 0.116 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.884 0.116 0.000
E05.9 Thyrotoxicosis, unspecified
0.883 0.117 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.879 0.121 0.000
A30-A49 Other bacterial diseases
0.876 0.124 0.000
C34.3 Lower lobe, bronchus or lung
0.874 0.126 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.869 0.131 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.867 0.133 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.856 0.144 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.854 0.146 0.000
Y43 Primarily systemic agents
0.854 0.146 0.000
O42 Premature rupture of membranes
0.852 0.148 0.000
X60-X84 Intentional self-harm
0.852 0.148 0.000
C67 Malignant neoplasm of bladder
0.851 0.149 0.000
B15-B19 Viral hepatitis
0.846 0.154 0.000
Chapter X Diseases of the respiratory system
0.843 0.157 0.000
O43 Placental disorders
0.838 0.162 0.000
S52.1 Fracture of upper end of radius
0.836 0.164 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.836 0.164 0.000
H80-H83 Diseases of inner ear
0.832 0.168 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.832 0.168 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.828 0.172 0.000
S62 Fracture at wrist and hand level
0.827 0.173 0.000
O72.2 Delayed and secondary postpartum haemorrhage
0.825 0.175 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.822 0.178 0.000
O72.0 Third-stage haemorrhage
0.820 0.180 0.000
O62 Abnormalities of forces of labour
0.818 0.182 0.000
T68 Hypothermia
0.817 0.183 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.816 0.184 0.000
C15.5 Lower third of oesophagus
0.816 0.184 0.000
O16 Unspecified maternal hypertension
0.815 0.185 0.000
O47 False labour
0.813 0.187 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.812 0.188 0.000
D60-D64 Aplastic and other anaemias
0.811 0.189 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.809 0.191 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.808 0.192 0.000
H72 Perforation of tympanic membrane
0.807 0.193 0.000
C34.2 Middle lobe, bronchus or lung
0.807 0.193 0.000
C16 Malignant neoplasm of stomach
0.806 0.194 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.805 0.195 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.804 0.196 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.803 0.197 0.000
D69.4 Other primary thrombocytopenia
0.802 0.198 0.000
S67 Crushing injury of wrist and hand
0.801 0.199 0.000
C34.1 Upper lobe, bronchus or lung
0.801 0.199 0.000
H69 Other disorders of Eustachian tube
0.800 0.200 0.000
O73 Retained placenta and membranes, without haemorrhage
0.799 0.201 0.000
E20-E35 Disorders of other endocrine glands
0.797 0.202 0.000
Y43.3 Other antineoplastic drugs
0.797 0.203 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.796 0.204 0.000
C18.9 Colon, unspecified
0.794 0.205 0.000
H90-H95 Other disorders of ear
0.794 0.206 0.000
S72 Fracture of femur
0.794 0.206 0.000
J95-J99 Other diseases of the respiratory system
0.794 0.206 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.793 0.207 0.000
C18.0 Caecum
0.793 0.207 0.000
W20-W49 Exposure to inanimate mechanical forces
0.792 0.208 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.791 0.208 0.000
D69.6 Thrombocytopenia, unspecified
0.791 0.209 0.000
Chapter XXII Codes for special purposes
0.789 0.211 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.789 0.211 0.000
C15.9 Oesophagus, unspecified
0.788 0.212 0.000
H66 Suppurative and unspecified otitis media
0.788 0.212 0.000
O80-O84 Delivery
0.787 0.213 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.786 0.214 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.786 0.214 0.000
S52.8 Fracture of other parts of forearm
0.785 0.215 0.000
A49 Bacterial infection of unspecified site
0.783 0.217 0.000
O32.4 Maternal care for high head at term
0.783 0.217 0.000
S00-S09 Injuries to the head
0.783 0.217 0.000
E07 Other disorders of thyroid
0.783 0.217 0.000
O72.1 Other immediate postpartum haemorrhage
0.778 0.222 0.000
S51.9 Open wound of forearm, part unspecified
0.778 0.222 0.000
A41 Other septicaemia
0.777 0.223 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.776 0.224 0.000
C34.0 Main bronchus
0.776 0.224 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.775 0.225 0.000
E40-E46 Malnutrition
0.774 0.226 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.773 0.227 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.772 0.228 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.770 0.230 0.000
W50-W64 Exposure to animate mechanical forces
0.768 0.231 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.767 0.233 0.000
D45 Polycythaemia vera
0.767 0.233 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.767 0.233 0.000
S90-S99 Injuries to the ankle and foot
0.766 0.234 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.765 0.235 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.765 0.235 0.000
C67.9 Bladder, unspecified
0.764 0.236 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.764 0.236 0.000
T66 Unspecified effects of radiation
0.763 0.237 0.000
J98 Other respiratory disorders
0.763 0.237 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.763 0.237 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.762 0.238 0.000
O46.9 Antepartum haemorrhage, unspecified
0.762 0.238 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.761 0.239 0.000
E04 Other non-toxic goitre
0.760 0.240 0.000
O41 Other disorders of amniotic fluid and membranes
0.759 0.241 0.000
H65 Nonsuppurative otitis media
0.759 0.241 0.000
T78 Adverse effects, not elsewhere classified
0.759 0.241 0.000
S52.10 Fracture of upper end of radius (closed)
0.759 0.241 0.000
X10-X19 Contact with heat and hot substances
0.758 0.242 0.000
D75 Other diseases of blood and blood-forming organs
0.758 0.242 0.000
C18.2 Ascending colon
0.756 0.244 0.000
T00-T07 Injuries involving multiple body regions
0.756 0.244 0.000
H83 Other diseases of inner ear
0.756 0.244 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.756 0.244 0.000
D69.5 Secondary thrombocytopenia
0.756 0.244 0.000
V80-V89 Other land transport accidents
0.754 0.246 0.000
Q60-Q64 Congenital malformations of the urinary system
0.753 0.247 0.000
S52.5 Fracture of lower end of radius
0.752 0.248 0.000
D68 Other coagulation defects
0.752 0.248 0.000
S52.6 Fracture of lower end of both ulna and radius
0.750 0.250 0.000
B18 Chronic viral hepatitis
0.750 0.250 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.749 0.251 0.000
S51.0 Open wound of elbow
0.749 0.251 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.748 0.252 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.748 0.252 0.000
D66 Hereditary factor VIII deficiency
0.748 0.252 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.746 0.254 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.744 0.256 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.743 0.256 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.743 0.257 0.000
C32 Malignant neoplasm of larynx
0.743 0.257 0.000
O32.8 Maternal care for other malpresentation of foetus
0.742 0.257 0.000
T21 Burn and corrosion of trunk
0.742 0.258 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.741 0.259 0.000
O85-O92 Complications predominantly related to the puerperium
0.740 0.259 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.739 0.261 0.000
D69.9 Haemorrhagic condition, unspecified
0.738 0.262 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.737 0.263 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.737 0.263 0.000
T39.1 4-Aminophenol derivatives
0.736 0.264 0.000
S70 Superficial injury of hip and thigh
0.735 0.264 0.000
D80-D89 Certain disorders involving the immune mechanism
0.735 0.265 0.000
E16 Other disorders of pancreatic internal secretion
0.735 0.265 0.000
T85.2 Mechanical complication of intraocular lens
0.734 0.266 0.000
H71 Cholesteatoma of middle ear
0.733 0.266 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.732 0.268 0.000
S62.3 Fracture of other metacarpal bone
0.731 0.269 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.731 0.269 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.729 0.271 0.000
S52.0 Fracture of upper end of ulna
0.728 0.272 0.000
O43.8 Other placental disorders
0.727 0.273 0.000
T82.3 Mechanical complication of other vascular grafts
0.725 0.275 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.724 0.276 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.724 0.276 0.000
Y40 Systemic antibiotics
0.723 0.277 0.000
Y52 Agents primarily affecting the cardiovascular system
0.722 0.278 0.000
C77.1 Intrathoracic lymph nodes
0.722 0.278 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.721 0.279 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.721 0.279 0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.719 0.281 0.000
C21 Malignant neoplasm of anus and anal canal
0.719 0.281 0.000
S10-S19 Injuries to the neck
0.718 0.282 0.000
T79-T79 Certain early complications of trauma
0.717 0.282 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.716 0.284 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.716 0.284 0.000
C31 Malignant neoplasm of accessory sinuses
0.716 0.284 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.716 0.284 0.000
C37 Malignant neoplasm of thymus
0.716 0.284 0.000
C33 Malignant neoplasm of trachea
0.716 0.284 0.000
C34.8 Overlapping lesion of bronchus and lung
0.716 0.284 0.000
O44 Placenta praevia
0.716 0.284 0.000
A00-A09 Intestinal infectious diseases
0.715 0.285 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.713 0.287 0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours
0.713 0.287 0.000
O66 Other obstructed labour
0.712 0.288 0.000
A41.9 Septicaemia, unspecified
0.712 0.288 0.000
C78.7 Secondary malignant neoplasm of liver
0.711 0.289 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.711 0.289 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.710 0.290 0.000
J81 Pulmonary oedema
0.709 0.291 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.709 0.291 0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level
0.708 0.292 0.000
E04.1 Non-toxic single thyroid nodule
0.708 0.292 0.000
O45 Premature separation of placenta [abruptio placentae]
0.708 0.292 0.000
O33 Maternal care for known or suspected disproportion
0.708 0.292 0.000
O31 Complications specific to multiple gestation
0.708 0.292 0.000
O40 Polyhydramnios
0.708 0.292 0.000
Chapter VI Diseases of the nervous system
0.708 0.292 0.000
S67.0 Crushing injury of thumb and other finger(s)
0.707 0.293 0.000
Y35-Y36 Legal intervention and operations of war
0.706 0.293 0.000
Y10-Y34 Event of undetermined intent
0.706 0.293 0.000
Y00-Y09 Assault
0.706 0.293 0.000
X85-X99 Assault
0.706 0.293 0.000
X50-X57 Overexertion, travel and privation
0.706 0.293 0.000
X30-X39 Exposure to forces of nature
0.706 0.293 0.000
X00-X09 Exposure to smoke, fire and flames
0.706 0.293 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.706 0.293 0.000
W75-W84 Other accidental threats to breathing
0.706 0.293 0.000
W65-W74 Accidental drowning and submersion
0.706 0.293 0.000
V98-V99 Other and unspecified transport accidents
0.706 0.293 0.000
V95-V97 Air and space transport accidents
0.706 0.293 0.000
V90-V94 Water transport accidents
0.706 0.293 0.000
V70-V79 Bus occupant injured in transport accident
0.706 0.293 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.706 0.293 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.706 0.293 0.000
V40-V49 Car occupant injured in transport accident
0.706 0.293 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.706 0.293 0.000
V01-V09 Pedestrian injured in transport accident
0.706 0.293 0.000
D55-D59 Haemolytic anaemias
0.706 0.294 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.706 0.294 0.000
W00-W19 Falls
0.706 0.294 0.000
H93 Other disorders of ear, not elsewhere classified
0.705 0.295 0.000
O74 Complications of anaesthesia during labour and delivery
0.704 0.296 0.000
O71 Other obstetric trauma
0.704 0.296 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.704 0.296 0.000
O60 Preterm delivery
0.704 0.296 0.000
X69 Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
0.704 0.296 0.000
S59 Other and unspecified injuries of forearm
0.703 0.297 0.000
S58 Traumatic amputation of forearm
0.703 0.297 0.000
S57 Crushing injury of forearm
0.703 0.297 0.000
S56 Injury of muscle and tendon at forearm level
0.703 0.297 0.000
S55 Injury of blood vessels at forearm level
0.703 0.297 0.000
S54 Injury of nerves at forearm level
0.703 0.297 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.703 0.297 0.000
B65-B83 Helminthiases
0.702 0.298 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.702 0.298 0.000
H83.0 Labyrinthitis
0.701 0.299 0.000
E22 Hyperfunction of pituitary gland
0.700 0.300 0.000
C51-C58 Malignant neoplasms of female genital organs
0.700 0.300 0.000
D63.0 Anaemia in neoplastic disease
0.699 0.301 0.000
H69.9 Eustachian tube disorder, unspecified
0.699 0.301 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.698 0.302 0.000
T87 Complications peculiar to reattachment and amputation
0.697 0.302 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.697 0.303 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.696 0.304 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.696 0.304 0.000
Q50-Q56 Congenital malformations of genital organs
0.696 0.304 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.696 0.304 0.000
C17 Malignant neoplasm of small intestine
0.696 0.304 0.000
C23 Malignant neoplasm of gallbladder
0.696 0.304 0.000
T31 Burns classified according to extent of body surface involved
0.695 0.305 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.693 0.307 0.000
O61 Failed induction of labour
0.693 0.307 0.000
C18.5 Splenic flexure
0.693 0.307 0.000
D67 Hereditary factor IX deficiency
0.692 0.308 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.692 0.308 0.000
C67.5 Bladder neck
0.692 0.308 0.000
T23 Burn and corrosion of wrist and hand
0.690 0.310 0.000
X20-X29 Contact with venomous animals and plants
0.690 0.310 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.689 0.311 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.689 0.311 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.689 0.311 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.689 0.311 0.000
A49.8 Other bacterial infections of unspecified site
0.689 0.311 0.000
B02 Zoster [herpes zoster]
0.687 0.313 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.686 0.313 0.000
C78.2 Secondary malignant neoplasm of pleura
0.686 0.314 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.686 0.314 0.000
H74 Other disorders of middle ear and mastoid
0.686 0.314 0.000
O62.2 Other uterine inertia
0.685 0.315 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.685 0.315 0.000
C79.2 Secondary malignant neoplasm of skin
0.684 0.316 0.000
Chapter XXI Factors influencing health status and contact with health services
0.683 0.317 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.682 0.318 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.682 0.318 0.000
Q80-Q89 Other congenital malformations
0.681 0.318 0.000
D38.1 Trachea, bronchus and lung
0.680 0.320 0.000
O32.9 Maternal care for malpresentation of foetus, unspecified
0.680 0.320 0.000
O32.6 Maternal care for compound presentation
0.680 0.320 0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more
0.680 0.320 0.000
O32.3 Maternal care for face, brow and chin presentation
0.680 0.320 0.000
O32.2 Maternal care for transverse and oblique lie
0.680 0.320 0.000
B16 Acute hepatitis B
0.679 0.321 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.679 0.321 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.679 0.321 0.000
O32.0 Maternal care for unstable lie
0.679 0.321 0.000
A80-A89 Viral infections of the central nervous system
0.677 0.323 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.677 0.323 0.000
S52.9 Fracture of forearm, part unspecified
0.676 0.323 0.000
S52.7 Multiple fractures of forearm
0.676 0.323 0.000
S52.4 Fracture of shafts of both ulna and radius
0.676 0.323 0.000
S52.3 Fracture of shaft of radius
0.676 0.323 0.000
S52.2 Fracture of shaft of ulna
0.676 0.323 0.000
B00 Herpesviral [herpes simplex] infections
0.676 0.324 0.000
E07.9 Disorder of thyroid, unspecified
0.676 0.324 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.675 0.325 0.000
H70 Mastoiditis and related conditions
0.675 0.325 0.000
H68 Eustachian salpingitis and obstruction
0.675 0.325 0.000
H67 Otitis media in diseases classified elsewhere
0.675 0.325 0.000
D69.8 Other specified haemorrhagic conditions
0.675 0.325 0.000
D69.2 Other nonthrombocytopenic purpura
0.675 0.325 0.000
D69.1 Qualitative platelet defects
0.675 0.325 0.000
D69.0 Allergic purpura
0.675 0.325 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.675 0.325 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.675 0.325 0.000
B50-B64 Protozoal diseases
0.675 0.325 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.675 0.325 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.675 0.325 0.000
A75-A79 Rickettsioses
0.675 0.325 0.000
A70-A74 Other diseases caused by chlamydiae
0.675 0.325 0.000
A65-A69 Other spirochaetal diseases
0.675 0.325 0.000
A20-A28 Certain zoonotic bacterial diseases
0.675 0.325 0.000
A15-A19 Tuberculosis
0.675 0.325 0.000
Y84.2 Radiological procedure and radiotherapy
0.674 0.326 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.674 0.326 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.673 0.327 0.000
E10-E14 Diabetes mellitus
0.673 0.327 0.000
O72.3 Postpartum coagulation defects
0.673 0.327 0.000
T20 Burn and corrosion of head and neck
0.673 0.327 0.000
D68.5 Primary Thrombophilia
0.671 0.329 0.000
S52.80 Fracture of other parts of forearm (closed)
0.671 0.329 0.000
S50 Superficial injury of forearm
0.670 0.330 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.670 0.330 0.000
C67.4 Posterior wall of bladder
0.670 0.330 0.000
S65 Injury of blood vessels at wrist and hand level
0.669 0.331 0.000
O73.0 Retained placenta, without haemorrhage
0.669 0.331 0.000
T75 Effects of other external causes
0.668 0.331 0.000
T74 Maltreatment syndromes
0.668 0.331 0.000
T73 Effects of other deprivation
0.668 0.331 0.000
T70 Effects of air pressure and water pressure
0.668 0.331 0.000
T69 Other effects of reduced temperature
0.668 0.331 0.000
T67 Effects of heat and light
0.668 0.331 0.000
T71 Asphyxiation
0.668 0.331 0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system
0.668 0.331 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.668 0.332 0.000
E00 Congenital iodine-deficiency syndrome
0.668 0.332 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.668 0.332 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.668 0.332 0.000
H66.9 Otitis media, unspecified
0.668 0.332 0.000
B18.2 Chronic viral hepatitis C
0.666 0.334 0.000
H72.0 Central perforation of tympanic membrane
0.666 0.334 0.000
S72.8 Fractures of other parts of femur
0.665 0.335 0.000
E16.2 Hypoglycaemia, unspecified
0.665 0.335 0.000
D47.1 Chronic myeloproliferative disease
0.664 0.336 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.664 0.336 0.000
C67.0 Trigone of bladder
0.664 0.336 0.000
Y84.8 Other medical procedures
0.664 0.336 0.000
B99-B99 Other infectious diseases
0.663 0.337 0.000
B35-B49 Mycoses
0.663 0.337 0.000
S00 Superficial injury of head
0.663 0.337 0.000
S62.30 Fracture of other metacarpal bone (closed)
0.662 0.338 0.000
C16.9 Stomach, unspecified
0.662 0.338 0.000
E23 Hypofunction and other disorders of pituitary gland
0.662 0.338 0.000
S40-S49 Injuries to the shoulder and upper arm
0.662 0.338 0.000
H66.4 Suppurative otitis media, unspecified
0.661 0.338 0.000
Q61 Cystic kidney disease
0.661 0.339 0.000
H90 Conductive and sensorineural hearing loss
0.661 0.339 0.000
C67.6 Ureteric orifice
0.660 0.340 0.000
S71 Open wound of hip and thigh
0.660 0.340 0.000
V10-V19 Pedal cyclist injured in transport accident
0.659 0.340 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.659 0.341 0.000
Y43.4 Immunosuppressive agents
0.659 0.341 0.000
C67.3 Anterior wall of bladder
0.658 0.342 0.000
O15 Eclampsia
0.658 0.342 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.658 0.342 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.658 0.342 0.000
Y59 Other and unspecified vaccines and biological substances
0.657 0.342 0.000
Y58 Bacterial vaccines
0.657 0.342 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.657 0.342 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.657 0.342 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.657 0.342 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.657 0.342 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.657 0.342 0.000
Y48 Anaesthetics and therapeutic gases
0.657 0.342 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.657 0.342 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.657 0.342 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.657 0.342 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.656 0.344 0.000
W49 Exposure to other and unspecified inanimate mechanical forces
0.656 0.344 0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head
0.655 0.345 0.000
H60-H62 Diseases of external ear
0.655 0.345 0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
0.655 0.345 0.000
O35.8 Maternal care for other (suspected) foetal abnormality and damage
0.654 0.346 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.653 0.347 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.653 0.347 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.653 0.347 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.653 0.347 0.000
J40-J47 Chronic lower respiratory diseases
0.653 0.347 0.000
C15.8 Overlapping lesion of oesophagus
0.652 0.348 0.000
C15.4 Middle third of oesophagus
0.652 0.348 0.000
C15.3 Upper third of oesophagus
0.652 0.348 0.000
C15.2 Abdominal part of oesophagus
0.652 0.348 0.000
C15.1 Thoracic part of oesophagus
0.652 0.348 0.000
C15.0 Cervical part of oesophagus
0.652 0.348 0.000
C18.3 Hepatic flexure
0.652 0.348 0.000
D75.8 Other specified diseases of blood and blood-forming organs
0.651 0.349 0.000
D48.1 Connective and other soft tissue
0.651 0.349 0.000
T86 Failure and rejection of transplanted organs and tissues
0.650 0.350 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.649 0.351 0.000
D75.1 Secondary polycythaemia
0.648 0.352 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.648 0.352 0.000
C66 Malignant neoplasm of ureter
0.648 0.352 0.000
S79 Other and unspecified injuries of hip and thigh
0.648 0.352 0.000
S78 Traumatic amputation of hip and thigh
0.648 0.352 0.000
S77 Crushing injury of hip and thigh
0.648 0.352 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.648 0.352 0.000
S75 Injury of blood vessels at hip and thigh level
0.648 0.352 0.000
S74 Injury of nerves at hip and thigh level
0.648 0.352 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.648 0.352 0.000
C18.8 Overlapping lesion of colon
0.648 0.352 0.000
C18.1 Appendix
0.648 0.352 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.647 0.353 0.000
S20-S29 Injuries to the thorax
0.646 0.354 0.000
S72.0 Fracture of neck of femur
0.646 0.354 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.646 0.354 0.000
V20-V29 Motorcycle rider injured in transport accident
0.645 0.354 0.000
C18.6 Descending colon
0.645 0.355 0.000
S62.6 Fracture of other finger
0.645 0.355 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.644 0.355 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.644 0.356 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.643 0.356 0.000
T21.0 Burn of unspecified degree of trunk
0.643 0.357 0.000
S06 Intracranial injury
0.643 0.357 0.000
E05.8 Other thyrotoxicosis
0.642 0.358 0.000
E05.5 Thyroid crisis or storm
0.642 0.358 0.000
E05.4 Thyrotoxicosis factitia
0.642 0.358 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.642 0.358 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.642 0.358 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.642 0.358 0.000
S72.4 Fracture of lower end of femur
0.642 0.358 0.000
W29 Contact with other powered hand tools and household machinery
0.640 0.360 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.640 0.360 0.000
O97 Death from sequelae of direct obstetric causes
0.640 0.360 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.640 0.360 0.000
O95 Obstetric death of unspecified cause
0.640 0.360 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.640 0.360 0.000
C77.0 Lymph nodes of head, face and neck
0.640 0.360 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.639 0.361 0.000
C65 Malignant neoplasm of renal pelvis
0.639 0.361 0.000
Y44 Agents primarily affecting blood constituents
0.639 0.361 0.000
C80 Malignant neoplasm without specification of site
0.639 0.361 0.000
S51.8 Open wound of other parts of forearm
0.639 0.361 0.000
S51.7 Multiple open wounds of forearm
0.639 0.361 0.000
O30 Multiple gestation
0.639 0.361 0.000
C77.5 Intrapelvic lymph nodes
0.636 0.364 0.000
E46 Unspecified protein-energy malnutrition
0.636 0.364 0.000
O63 Long labour
0.635 0.365 0.000
H65.4 Other chronic nonsuppurative otitis media
0.635 0.365 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.634 0.366 0.000
Q35-Q37 Cleft lip and cleft palate
0.634 0.366 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.634 0.366 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.634 0.366 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.634 0.366 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.634 0.366 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.634 0.366 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.634 0.366 0.000
T36 Poisoning by systemic antibiotics
0.634 0.366 0.000
S60 Superficial injury of wrist and hand
0.633 0.367 0.000
X78 Intentional self-harm by sharp object
0.632 0.368 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.632 0.368 0.000
A49.9 Bacterial infection, unspecified
0.632 0.368 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.631 0.368 0.000
Z22 Carrier of infectious disease
0.631 0.369 0.000
T25 Burn and corrosion of ankle and foot
0.630 0.370 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.630 0.370 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.630 0.370 0.000
E65-E68 Obesity and other hyperalimentation
0.629 0.371 0.000
C20 Malignant neoplasm of rectum
0.629 0.371 0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level
0.629 0.371 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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