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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs114927259
log Bayes Factor = 6.36727
Chromosome 2   position 108,678,685  (GRCh37) Explore rs114927259 on Ensembl!
Variant rs114927259 is part of Cluster X0221

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
Chapter II Neoplasms
0.997 0.003 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.996 0.004 0.000
D00-D09 In situ neoplasms
0.994 0.006 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.987 0.013 0.000
S60-S69 Injuries to the wrist and hand
0.984 0.016 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.982 0.018 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.980 0.020 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.979 0.021 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.973 0.027 0.000
M20-M25 Other joint disorders
0.970 0.030 0.000
T81 Complications of procedures, not elsewhere classified
0.970 0.030 0.000
Chapter IX Diseases of the circulatory system
0.968 0.032 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.967 0.033 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.963 0.037 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.963 0.037 0.000
D05 Carcinoma in situ of breast
0.963 0.037 0.000
T82.3 Mechanical complication of other vascular grafts
0.958 0.042 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.956 0.044 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.955 0.045 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.948 0.052 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.945 0.055 0.000
Q60-Q64 Congenital malformations of the urinary system
0.942 0.058 0.000
S60 Superficial injury of wrist and hand
0.942 0.058 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.938 0.062 0.000
M31 Other necrotising vasculopathies
0.928 0.072 0.000
D03 Melanoma in situ
0.928 0.072 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.923 0.077 0.000
I77 Other disorders of arteries and arterioles
0.922 0.078 0.000
D09 Carcinoma in situ of other and unspecified sites
0.916 0.084 0.000
I73 Other peripheral vascular diseases
0.914 0.086 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.913 0.087 0.000
Q61 Cystic kidney disease
0.907 0.093 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.902 0.098 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.900 0.100 0.000
S64 Injury of nerves at wrist and hand level
0.899 0.101 0.000
M25 Other joint disorders, not elsewhere classified
0.896 0.104 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.894 0.106 0.000
M31.6 Other giant cell arteritis
0.894 0.106 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.891 0.109 0.000
Y83.9 Surgical procedure, unspecified
0.891 0.109 0.000
S60.8 Other superficial injuries of wrist and hand
0.889 0.111 0.000
D60-D64 Aplastic and other anaemias
0.885 0.115 0.000
I73.9 Peripheral vascular disease, unspecified
0.885 0.115 0.000
S40-S49 Injuries to the shoulder and upper arm
0.882 0.118 0.000
V20-V29 Motorcycle rider injured in transport accident
0.881 0.119 0.000
M86-M90 Other osteopathies
0.880 0.120 0.000
T23 Burn and corrosion of wrist and hand
0.878 0.122 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.878 0.122 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.871 0.129 0.000
D69 Purpura and other haemorrhagic conditions
0.871 0.129 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.868 0.132 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.867 0.133 0.000
I74 Arterial embolism and thrombosis
0.864 0.136 0.000
Q61.3 Polycystic kidney, unspecified
0.862 0.138 0.000
D09.0 Bladder
0.860 0.140 0.000
M24 Other specific joint derangements
0.853 0.147 0.000
C51-C58 Malignant neoplasms of female genital organs
0.850 0.150 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.849 0.150 0.000
I77.1 Stricture of artery
0.849 0.151 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.848 0.152 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.844 0.156 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.842 0.158 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.837 0.163 0.000
S64.4 Injury of digital nerve of other finger
0.835 0.165 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.834 0.166 0.000
M22 Disorders of patella
0.831 0.169 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.829 0.171 0.000
D03.7 Melanoma in situ of lower limb, including hip
0.824 0.176 0.000
M21 Other acquired deformities of limbs
0.823 0.177 0.000
S70-S79 Injuries to the hip and thigh
0.822 0.178 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.817 0.183 0.000
M60-M63 Disorders of muscles
0.816 0.184 0.000
I70 Atherosclerosis
0.816 0.184 0.000
D63.0 Anaemia in neoplastic disease
0.812 0.188 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.812 0.188 0.000
Y57 Other and unspecified drugs and medicaments
0.811 0.188 0.000
M50-M54 Other dorsopathies
0.811 0.189 0.000
M65-M68 Disorders of synovium and tendon
0.808 0.192 0.000
W50-W64 Exposure to animate mechanical forces
0.807 0.192 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.806 0.194 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.804 0.196 0.000
S10-S19 Injuries to the neck
0.799 0.201 0.000
I30-I52 Other forms of heart disease
0.799 0.201 0.000
D80-D89 Certain disorders involving the immune mechanism
0.797 0.203 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.791 0.209 0.000
W00-W19 Falls
0.791 0.209 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.789 0.211 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.789 0.211 0.000
M00-M03 Infectious arthropathies
0.789 0.211 0.000
S20-S29 Injuries to the thorax
0.788 0.212 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.784 0.216 0.000
T23.2 Burn of second degree of wrist and hand
0.783 0.217 0.000
D03.3 Melanoma in situ of other and unspecified parts of face
0.780 0.220 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.780 0.220 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.777 0.223 0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract
0.776 0.224 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.775 0.225 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.774 0.226 0.000
T31 Burns classified according to extent of body surface involved
0.774 0.226 0.000
T00-T07 Injuries involving multiple body regions
0.772 0.228 0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van
0.772 0.228 0.000
D04 Carcinoma in situ of skin
0.771 0.229 0.000
M25.5 Pain in joint
0.770 0.230 0.000
Y43 Primarily systemic agents
0.768 0.232 0.000
V40-V49 Car occupant injured in transport accident
0.768 0.232 0.000
C85.1 B-cell lymphoma, unspecified
0.767 0.233 0.000
M25.9 Joint disorder, unspecified
0.767 0.233 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.767 0.233 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.766 0.234 0.000
Y83.4 Other reconstructive surgery
0.766 0.234 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.765 0.235 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.765 0.235 0.000
T20 Burn and corrosion of head and neck
0.762 0.238 0.000
Y48 Anaesthetics and therapeutic gases
0.762 0.238 0.000
X60-X84 Intentional self-harm
0.762 0.238 0.000
Y59 Other and unspecified vaccines and biological substances
0.759 0.241 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.758 0.242 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.757 0.243 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.757 0.243 0.000
Y52 Agents primarily affecting the cardiovascular system
0.756 0.244 0.000
I72 Other aneurysm
0.756 0.244 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.755 0.245 0.000
Y44 Agents primarily affecting blood constituents
0.754 0.246 0.000
Y83.0 Surgical operation with transplant of whole organ
0.754 0.246 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.753 0.247 0.000
S62 Fracture at wrist and hand level
0.753 0.247 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.751 0.248 0.000
S65 Injury of blood vessels at wrist and hand level
0.751 0.249 0.000
M91-M94 Chondropathies
0.749 0.250 0.000
Q43 Other congenital malformations of intestine
0.749 0.251 0.000
T86 Failure and rejection of transplanted organs and tissues
0.749 0.251 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.749 0.251 0.000
M89 Other disorders of bone
0.748 0.252 0.000
M90 Osteopathies in diseases classified elsewhere
0.748 0.252 0.000
M22.3 Other derangements of patella
0.747 0.252 0.000
T91 Sequelae of injuries of neck and trunk
0.745 0.255 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.745 0.255 0.000
T21 Burn and corrosion of trunk
0.745 0.255 0.000
Y00-Y09 Assault
0.744 0.256 0.000
S90-S99 Injuries to the ankle and foot
0.743 0.257 0.000
I78 Diseases of capillaries
0.742 0.258 0.000
C54 Malignant neoplasm of corpus uteri
0.741 0.259 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.736 0.264 0.000
T23.0 Burn of unspecified degree of wrist and hand
0.735 0.265 0.000
Y40 Systemic antibiotics
0.734 0.266 0.000
X20-X29 Contact with venomous animals and plants
0.733 0.267 0.000
Q61.2 Polycystic kidney, adult type
0.732 0.267 0.000
M45-M49 Spondylopathies
0.732 0.268 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.730 0.270 0.000
Q61.9 Cystic kidney disease, unspecified
0.730 0.270 0.000
Y84.8 Other medical procedures
0.729 0.271 0.000
S60.2 Contusion of other parts of wrist and hand
0.728 0.272 0.000
T90 Sequelae of injuries of head
0.728 0.272 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.727 0.273 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.727 0.273 0.000
I60-I69 Cerebrovascular diseases
0.726 0.274 0.000
S64.3 Injury of digital nerve of thumb
0.725 0.275 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.724 0.275 0.000
S40 Superficial injury of shoulder and upper arm
0.724 0.276 0.000
D05.0 Lobular carcinoma in situ
0.724 0.276 0.000
S60.0 Contusion of finger(s) without damage to nail
0.723 0.277 0.000
V80-V89 Other land transport accidents
0.722 0.277 0.000
Q61.5 Medullary cystic kidney
0.721 0.279 0.000
M22.2 Patellofemoral disorders
0.721 0.279 0.000
T79-T79 Certain early complications of trauma
0.720 0.280 0.000
M25.57 Pain in joint (Ankle and foot)
0.720 0.280 0.000
M35 Other systemic involvement of connective tissue
0.719 0.281 0.000
C60-C63 Malignant neoplasms of male genital organs
0.718 0.281 0.000
C64-C68 Malignant neoplasms of urinary tract
0.718 0.282 0.000
I35 Nonrheumatic aortic valve disorders
0.718 0.282 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.718 0.282 0.000
D69.9 Haemorrhagic condition, unspecified
0.717 0.282 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.717 0.283 0.000
Y10-Y34 Event of undetermined intent
0.717 0.283 0.000
X85-X99 Assault
0.717 0.283 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.717 0.283 0.000
X30-X39 Exposure to forces of nature
0.717 0.283 0.000
X10-X19 Contact with heat and hot substances
0.717 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.717 0.283 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.717 0.283 0.000
W75-W84 Other accidental threats to breathing
0.717 0.283 0.000
W65-W74 Accidental drowning and submersion
0.717 0.283 0.000
V98-V99 Other and unspecified transport accidents
0.717 0.283 0.000
V95-V97 Air and space transport accidents
0.717 0.283 0.000
V90-V94 Water transport accidents
0.717 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.717 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.717 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.717 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.717 0.283 0.000
V01-V09 Pedestrian injured in transport accident
0.717 0.283 0.000
M25.4 Effusion of joint
0.716 0.284 0.000
S60.9 Superficial injury of wrist and hand, unspecified
0.716 0.284 0.000
Q00-Q07 Congenital malformations of the nervous system
0.715 0.285 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.715 0.285 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.715 0.285 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.714 0.286 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.714 0.286 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.714 0.286 0.000
M25.0 Haemarthrosis
0.713 0.287 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.713 0.287 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.712 0.288 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.712 0.288 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.712 0.288 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.711 0.289 0.000
S72 Fracture of femur
0.710 0.290 0.000
V10-V19 Pedal cyclist injured in transport accident
0.710 0.290 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.709 0.291 0.000
T82.1 Mechanical complication of cardiac electronic device
0.709 0.291 0.000
D66 Hereditary factor VIII deficiency
0.708 0.292 0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft
0.708 0.292 0.000
T83.2 Mechanical complication of graft of urinary organ
0.708 0.292 0.000
S68 Traumatic amputation of wrist and hand
0.707 0.293 0.000
S67 Crushing injury of wrist and hand
0.707 0.293 0.000
Q63 Other congenital malformations of kidney
0.707 0.293 0.000
Y60.8 During other surgical and medical care
0.707 0.293 0.000
T31.0 Burns involving less than 10% of body surface
0.707 0.293 0.000
T14 Injury of unspecified body region
0.706 0.294 0.000
S69 Other and unspecified injuries of wrist and hand
0.704 0.296 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.702 0.298 0.000
Q35-Q37 Cleft lip and cleft palate
0.702 0.298 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.702 0.298 0.000
D03.5 Melanoma in situ of trunk
0.702 0.298 0.000
L20-L30 Dermatitis and eczema
0.702 0.298 0.000
I77.8 Other specified disorders of arteries and arterioles
0.699 0.301 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.698 0.302 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.698 0.302 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.695 0.304 0.000
M33 Dermatopolymyositis
0.695 0.304 0.000
M32 Systemic lupus erythematosus
0.695 0.304 0.000
M30 Polyarteritis nodosa and related conditions
0.695 0.304 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.695 0.305 0.000
Q80-Q89 Other congenital malformations
0.695 0.305 0.000
Y65 Other misadventures during surgical and medical care
0.695 0.305 0.000
C15-C26 Malignant neoplasms of digestive organs
0.694 0.306 0.000
I00-I02 Acute rheumatic fever
0.694 0.306 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.694 0.306 0.000
V23.4 Driver injured in traffic accident
0.694 0.306 0.000
Y84.1 Kidney dialysis
0.694 0.306 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.693 0.306 0.000
D69.5 Secondary thrombocytopenia
0.693 0.307 0.000
M31.3 Wegener's granulomatosis
0.693 0.307 0.000
Y45.0 Opioids and related analgesics
0.693 0.307 0.000
S41 Open wound of shoulder and upper arm
0.691 0.309 0.000
D61 Other aplastic anaemias
0.691 0.309 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.690 0.310 0.000
D55-D59 Haemolytic anaemias
0.690 0.310 0.000
D05.7 Other carcinoma in situ of breast
0.690 0.310 0.000
W20-W49 Exposure to inanimate mechanical forces
0.690 0.310 0.000
X50-X57 Overexertion, travel and privation
0.689 0.311 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.689 0.311 0.000
C97 Malignant neoplasms of independent (primary) multiple sites
0.688 0.312 0.000
V28 Motorcycle rider injured in noncollision transport accident
0.686 0.313 0.000
T25 Burn and corrosion of ankle and foot
0.685 0.315 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.685 0.315 0.000
Y58 Bacterial vaccines
0.685 0.315 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.685 0.315 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.685 0.315 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.685 0.315 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.685 0.315 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.685 0.315 0.000
M24.2 Disorder of ligament
0.685 0.315 0.000
M54 Dorsalgia
0.685 0.315 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.682 0.318 0.000
I44 Atrioventricular and left bundle-branch block
0.681 0.319 0.000
D03.6 Melanoma in situ of upper limb, including shoulder
0.681 0.319 0.000
D48.5 Skin
0.680 0.320 0.000
M60 Myositis
0.680 0.320 0.000
M25.3 Other instability of joint
0.680 0.320 0.000
D04.5 Skin of trunk
0.679 0.321 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.679 0.321 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.678 0.322 0.000
Q64 Other congenital malformations of urinary system
0.676 0.324 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.676 0.324 0.000
S60.7 Multiple superficial injuries of wrist and hand
0.676 0.324 0.000
S60.1 Contusion of finger(s) with damage to nail
0.676 0.324 0.000
D41.4 Bladder
0.675 0.325 0.000
I50 Heart failure
0.674 0.326 0.000
C09 Malignant neoplasm of tonsil
0.673 0.327 0.000
C82.0 Small cleaved cell, follicular
0.673 0.327 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.673 0.327 0.000
C95 Leukaemia of unspecified cell type
0.673 0.327 0.000
C94 Other leukaemias of specified cell type
0.673 0.327 0.000
C93 Monocytic leukaemia
0.673 0.327 0.000
C88 Malignant immunoproliferative diseases
0.673 0.327 0.000
C86 Other specified types of T/NK-cell lymphoma
0.673 0.327 0.000
M34 Systemic sclerosis
0.672 0.327 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.672 0.328 0.000
C15 Malignant neoplasm of oesophagus
0.672 0.328 0.000
T87 Complications peculiar to reattachment and amputation
0.671 0.329 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.671 0.329 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.671 0.329 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.670 0.330 0.000
I49 Other cardiac arrhythmias
0.670 0.330 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.669 0.331 0.000
D69.6 Thrombocytopenia, unspecified
0.669 0.331 0.000
S19 Other and unspecified injuries of neck
0.668 0.332 0.000
Y83.6 Removal of other organ (partial) (total)
0.668 0.332 0.000
Y79 Orthopaedic devices associated with adverse incidents
0.667 0.333 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.667 0.333 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.665 0.334 0.000
M31.9 Necrotising vasculopathy, unspecified
0.665 0.335 0.000
M31.8 Other specified necrotising vasculopathies
0.665 0.335 0.000
M31.7 Microscopic polyangiitis
0.665 0.335 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.665 0.335 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.665 0.335 0.000
M31.2 Lethal midline granuloma
0.665 0.335 0.000
M31.1 Thrombotic microangiopathy
0.665 0.335 0.000
M31.0 Hypersensitivity angiitis
0.665 0.335 0.000
D03.9 Melanoma in situ, unspecified
0.665 0.335 0.000
D03.8 Melanoma in situ of other sites
0.665 0.335 0.000
D03.4 Melanoma in situ of scalp and neck
0.665 0.335 0.000
D03.2 Melanoma in situ of ear and external auricular canal
0.665 0.335 0.000
D03.1 Melanoma in situ of eyelid, including canthus
0.665 0.335 0.000
D03.0 Melanoma in situ of lip
0.665 0.335 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.665 0.335 0.000
W57 Bitten or stung by non-venomous insect and other non-venomous arthropods
0.665 0.335 0.000
M67 Other disorders of synovium and tendon
0.664 0.336 0.000
C51 Malignant neoplasm of vulva
0.664 0.336 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.663 0.337 0.000
C54.1 Endometrium
0.663 0.337 0.000
Y60.0 During surgical operation
0.663 0.337 0.000
Y43.3 Other antineoplastic drugs
0.663 0.337 0.000
S42 Fracture of shoulder and upper arm
0.663 0.337 0.000
I74.8 Embolism and thrombosis of other arteries
0.662 0.338 0.000
S72.0 Fracture of neck of femur
0.661 0.339 0.000
I77.5 Necrosis of artery
0.661 0.339 0.000
I77.4 Coeliac artery compression syndrome
0.661 0.339 0.000
I77.3 Arterial fibromuscular dysplasia
0.661 0.339 0.000
I77.2 Rupture of artery
0.661 0.339 0.000
I77.0 Arteriovenous fistula, acquired
0.661 0.339 0.000
C53 Malignant neoplasm of cervix uteri
0.659 0.341 0.000
Y57.9 Drug or medicament, unspecified
0.657 0.343 0.000
D09.9 Carcinoma in situ, unspecified
0.656 0.343 0.000
D09.7 Carcinoma in situ of other specified sites
0.656 0.343 0.000
D09.3 Thyroid and other endocrine glands
0.656 0.343 0.000
D09.2 Eye
0.656 0.343 0.000
D09.1 Other and unspecified urinary organs
0.656 0.343 0.000
M25.59 Pain in joint (Site unspecified)
0.656 0.344 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.656 0.344 0.000
I73.8 Other specified peripheral vascular diseases
0.656 0.344 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.656 0.344 0.000
M21.6 Other acquired deformities of ankle and foot
0.655 0.345 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.654 0.345 0.000
D67 Hereditary factor IX deficiency
0.654 0.346 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.654 0.346 0.000
M90.7 Fracture of bone in neoplastic disease
0.654 0.346 0.000
T90.4 Sequelae of injury of eye and orbit
0.654 0.346 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.652 0.348 0.000
I77.6 Arteritis, unspecified
0.651 0.349 0.000
Q61.8 Other cystic kidney diseases
0.651 0.349 0.000
Q61.4 Renal dysplasia
0.651 0.349 0.000
Q61.1 Polycystic kidney, infantile type
0.651 0.349 0.000
M00 Pyogenic arthritis
0.650 0.349 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.650 0.350 0.000
M53 Other dorsopathies, not elsewhere classified
0.650 0.350 0.000
C15.5 Lower third of oesophagus
0.649 0.351 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.648 0.352 0.000
W18 Other fall on same level
0.647 0.353 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.646 0.354 0.000
Y84.2 Radiological procedure and radiotherapy
0.646 0.354 0.000
Q43.0 Meckel's diverticulum
0.646 0.354 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.646 0.354 0.000
Y64 Contaminated medical or biological substances
0.645 0.355 0.000
Y63 Failure in dosage during surgical and medical care
0.645 0.355 0.000
Y62 Failure of sterile precautions during surgical and medical care
0.645 0.355 0.000
Y61 Foreign object accidentally left in body during surgical and medical care
0.645 0.355 0.000
Y69 Unspecified misadventure during surgical and medical care
0.645 0.355 0.000
Y66 Nonadministration of surgical and medical care
0.645 0.355 0.000
S64.9 Injury of unspecified nerve at wrist and hand level
0.645 0.355 0.000
S64.8 Injury of other nerves at wrist and hand level
0.645 0.355 0.000
S64.7 Injury of multiple nerves at wrist and hand level
0.645 0.355 0.000
S64.1 Injury of median nerve at wrist and hand level
0.645 0.355 0.000
I71 Aortic aneurysm and dissection
0.644 0.356 0.000
Chapter VIII Diseases of the ear and mastoid process
0.644 0.356 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.643 0.357 0.000
Y57.5 X-ray contrast media
0.643 0.357 0.000
I37 Pulmonary valve disorders
0.643 0.357 0.000
M25.2 Flail joint
0.642 0.358 0.000
M25.1 Fistula of joint
0.642 0.358 0.000
D62 Acute posthaemorrhagic anaemia
0.642 0.358 0.000
Chapter I Certain infectious and parasitic diseases
0.642 0.358 0.000
I33 Acute and subacute endocarditis
0.641 0.359 0.000
M86 Osteomyelitis
0.640 0.360 0.000
M25.96 Joint disorder, unspecified (Lower leg)
0.640 0.360 0.000
M21.0 Valgus deformity, not elsewhere classified
0.640 0.360 0.000
T81.9 Unspecified complication of procedure
0.639 0.361 0.000
D84 Other immunodeficiencies
0.637 0.363 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.637 0.363 0.000
M89.9 Disorder of bone, unspecified
0.636 0.364 0.000
M46 Other inflammatory spondylopathies
0.636 0.364 0.000
D68 Other coagulation defects
0.635 0.365 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.634 0.365 0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level
0.634 0.366 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.633 0.366 0.000
I31 Other diseases of pericardium
0.633 0.367 0.000
M50 Cervical disk disorders
0.633 0.367 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.633 0.367 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.633 0.367 0.000
S29 Other and unspecified injuries of thorax
0.632 0.367 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.632 0.367 0.000
S48 Traumatic amputation of shoulder and upper arm
0.632 0.368 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.632 0.368 0.000
S44 Injury of nerves at shoulder and upper arm level
0.632 0.368 0.000
S47 Crushing injury of shoulder and upper arm
0.632 0.368 0.000
I30 Acute pericarditis
0.632 0.368 0.000
I35.9 Aortic valve disorder, unspecified
0.632 0.368 0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.632 0.368 0.000
V29 Motorcycle rider injured in other and unspecified transport accidents
0.632 0.368 0.000
V27 Motorcycle rider injured in collision with fixed or stationary object
0.632 0.368 0.000
V26 Motorcycle rider injured in collision with other nonmotor vehicle
0.632 0.368 0.000
V25 Motorcycle rider injured in collision with railway train or railway vehicle
0.632 0.368 0.000
V24 Motorcycle rider injured in collision with heavy transport vehicle or bus
0.632 0.368 0.000
V22 Motorcycle rider injured in collision with two- or three-wheeled motor vehicle
0.632 0.368 0.000
V21 Motorcycle rider injured in collision with pedal cycle
0.632 0.368 0.000
V20 Motorcycle rider injured in collision with pedestrian or animal
0.632 0.368 0.000
C45 Mesothelioma
0.631 0.368 0.000
M87 Osteonecrosis
0.631 0.369 0.000
M25.52 Pain in joint (Upper arm)
0.631 0.369 0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified
0.630 0.370 0.000
S62.6 Fracture of other finger
0.630 0.370 0.000
W07 Fall involving chair
0.630 0.370 0.000
T23.7 Corrosion of third degree of wrist and hand
0.630 0.370 0.000
T23.6 Corrosion of second degree of wrist and hand
0.630 0.370 0.000
T23.5 Corrosion of first degree of wrist and hand
0.630 0.370 0.000
T23.4 Corrosion of unspecified degree of wrist and hand
0.630 0.370 0.000
T23.3 Burn of third degree of wrist and hand
0.630 0.370 0.000
T23.1 Burn of first degree of wrist and hand
0.630 0.370 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.629 0.371 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.629 0.371 0.000
C85.0 Lymphosarcoma
0.629 0.371 0.000
I60 Subarachnoid haemorrhage
0.629 0.371 0.000
M21.3 Wrist or foot drop (acquired)
0.628 0.372 0.000
M45 Ankylosing spondylitis
0.628 0.372 0.000
S50-S59 Injuries to the elbow and forearm
0.627 0.372 0.000
Q12 Congenital lens malformations
0.627 0.373 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.627 0.373 0.000
I74.5 Embolism and thrombosis of iliac artery
0.627 0.373 0.000
S72.00 Fracture of neck of femur (closed)
0.626 0.373 0.000
L27 Dermatitis due to substances taken internally
0.625 0.375 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.625 0.375 0.000
D69.8 Other specified haemorrhagic conditions
0.624 0.376 0.000
D69.4 Other primary thrombocytopenia
0.624 0.376 0.000
D69.2 Other nonthrombocytopenic purpura
0.624 0.376 0.000
D69.1 Qualitative platelet defects
0.624 0.376 0.000
D69.0 Allergic purpura
0.624 0.376 0.000
T91.3 Sequelae of injury of spinal cord
0.624 0.376 0.000
T20.2 Burn of second degree of head and neck
0.624 0.376 0.000
Y48.3 Local anaesthetics
0.623 0.377 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.623 0.377 0.000
T32 Corrosions classified according to extent of body surface involved
0.623 0.377 0.000
T30 Burn and corrosion, body region unspecified
0.623 0.377 0.000
T29 Burns and corrosions of multiple body regions
0.623 0.377 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.621 0.379 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.621 0.379 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.621 0.379 0.000
M25.8 Other specified joint disorders
0.621 0.379 0.000
D63.8 Anaemia in other chronic diseases classified elsewhere
0.621 0.379 0.000
C91 Lymphoid leukaemia
0.621 0.379 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.619 0.380 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.619 0.380 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.619 0.380 0.000
W15 Fall from cliff
0.619 0.381 0.000
Y59.3 Immunoglobulin
0.618 0.382 0.000
M54.5 Low back pain
0.617 0.383 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.616 0.383 0.000
M62 Other disorders of muscle
0.616 0.384 0.000
D07.4 Penis
0.616 0.384 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.616 0.384 0.000
W08 Fall involving other furniture
0.616 0.384 0.000
Y84.6 Urinary catheterisation
0.615 0.385 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.615 0.385 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.614 0.386 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.614 0.386 0.000
M65 Synovitis and tenosynovitis
0.613 0.387 0.000
L91 Hypertrophic disorders of skin
0.613 0.387 0.000
M21.4 Flat foot [pes planus] (acquired)
0.612 0.388 0.000
L30 Other dermatitis
0.612 0.388 0.000
M24.9 Joint derangement, unspecified
0.612 0.388 0.000
M24.7 Protrusio acetabuli
0.612 0.388 0.000
M24.6 Ankylosis of joint
0.612 0.388 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.612 0.388 0.000
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand
0.611 0.389 0.000
M35.3 Polymyalgia rheumatica
0.610 0.390 0.000
Y44.2 Anticoagulants
0.610 0.390 0.000
C58 Malignant neoplasm of placenta
0.610 0.390 0.000
C52 Malignant neoplasm of vagina
0.610 0.390 0.000
S63.5 Sprain and strain of wrist
0.610 0.390 0.000
S12 Fracture of neck
0.610 0.390 0.000
T01 Open wounds involving multiple body regions
0.609 0.391 0.000
Q45 Other congenital malformations of digestive system
0.609 0.391 0.000
Q42 Congenital absence, atresia and stenosis of large intestine
0.609 0.391 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.609 0.391 0.000
Q40 Other congenital malformations of upper alimentary tract
0.609 0.391 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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