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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs115079764
log Bayes Factor = 11.3458
Chromosome 4   position 9,684,785  (GRCh37) Explore rs115079764 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.999 0.001 0.000
C15-C26 Malignant neoplasms of digestive organs
0.998 0.002 0.000
K70-K77 Diseases of liver
0.998 0.002 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.996 0.004 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.995 0.005 0.000
R50-R69 General symptoms and signs
0.991 0.009 0.000
I30-I52 Other forms of heart disease
0.990 0.010 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.989 0.011 0.000
K90-K93 Other diseases of the digestive system
0.986 0.014 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.986 0.014 0.000
C18 Malignant neoplasm of colon
0.984 0.016 0.000
C77.2 Intra-abdominal lymph nodes
0.984 0.016 0.000
C79 Secondary malignant neoplasm of other sites
0.978 0.022 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.977 0.023 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.976 0.024 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.975 0.025 0.000
K70 Alcoholic liver disease
0.975 0.025 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.973 0.027 0.000
K92 Other diseases of digestive system
0.972 0.028 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.971 0.029 0.000
I42 Cardiomyopathy
0.968 0.032 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.962 0.038 0.000
Chapter VI Diseases of the nervous system
0.959 0.041 0.000
R51 Headache
0.959 0.041 0.000
C77.9 Lymph node, unspecified
0.958 0.042 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.956 0.044 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.956 0.044 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.952 0.048 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.951 0.049 0.000
Chapter VIII Diseases of the ear and mastoid process
0.947 0.053 0.000
I73 Other peripheral vascular diseases
0.944 0.056 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.943 0.057 0.000
K92.1 Melaena
0.934 0.066 0.000
K92.2 Gastro-intestinal haemorrhage, unspecified
0.933 0.067 0.000
R63 Symptoms and signs concerning food and fluid intake
0.933 0.067 0.000
C78.2 Secondary malignant neoplasm of pleura
0.933 0.067 0.000
L03 Cellulitis
0.929 0.071 0.000
R50 Fever of unknown origin
0.926 0.074 0.000
I42.0 Dilated cardiomyopathy
0.926 0.074 0.000
C77.5 Intrapelvic lymph nodes
0.923 0.077 0.000
K70.3 Alcoholic cirrhosis of liver
0.921 0.079 0.000
G20-G26 Extrapyramidal and movement disorders
0.916 0.084 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.916 0.084 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.915 0.085 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.912 0.088 0.000
R63.0 Anorexia
0.909 0.091 0.000
K74 Fibrosis and cirrhosis of liver
0.907 0.093 0.000
K76 Other diseases of liver
0.905 0.095 0.000
H65-H75 Diseases of middle ear and mastoid
0.901 0.099 0.000
C18.2 Ascending colon
0.900 0.100 0.000
I05-I09 Chronic rheumatic heart diseases
0.900 0.100 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.898 0.101 0.000
C50-C50 Malignant neoplasm of breast
0.894 0.106 0.000
R29.6 Tendency to fall, not elsewhere classified
0.887 0.113 0.000
C18.7 Sigmoid colon
0.883 0.117 0.000
K81 Cholecystitis
0.882 0.118 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.880 0.120 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.880 0.120 0.000
L50-L54 Urticaria and erythema
0.880 0.120 0.000
R50.9 Fever, unspecified
0.879 0.121 0.000
I34 Nonrheumatic mitral valve disorders
0.876 0.124 0.000
G25 Other extrapyramidal and movement disorders
0.872 0.128 0.000
G90-G99 Other disorders of the nervous system
0.869 0.131 0.000
L03.9 Cellulitis, unspecified
0.869 0.131 0.000
K55-K64 Other diseases of intestines
0.868 0.132 0.000
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.867 0.133 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.865 0.135 0.000
K83 Other diseases of biliary tract
0.865 0.135 0.000
I42.9 Cardiomyopathy, unspecified
0.862 0.138 0.000
K81.9 Cholecystitis, unspecified
0.855 0.145 0.000
R25 Abnormal involuntary movements
0.854 0.146 0.000
R64 Cachexia
0.854 0.146 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.854 0.146 0.000
C79.6 Secondary malignant neoplasm of ovary
0.853 0.147 0.000
K85 Acute pancreatitis
0.853 0.147 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.853 0.147 0.000
C15 Malignant neoplasm of oesophagus
0.853 0.147 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.850 0.150 0.000
I73.0 Raynaud's syndrome
0.850 0.150 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.849 0.151 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.845 0.155 0.000
I73.9 Peripheral vascular disease, unspecified
0.843 0.157 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.842 0.158 0.000
T87 Complications peculiar to reattachment and amputation
0.842 0.158 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.839 0.161 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.838 0.162 0.000
R57 Shock, not elsewhere classified
0.837 0.163 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.837 0.163 0.000
R68 Other general symptoms and signs
0.836 0.164 0.000
I45 Other conduction disorders
0.834 0.166 0.000
K82 Other diseases of gallbladder
0.831 0.169 0.000
I47 Paroxysmal tachycardia
0.831 0.169 0.000
T79-T79 Certain early complications of trauma
0.828 0.172 0.000
K56.5 Intestinal adhesions [bands] with obstruction
0.827 0.173 0.000
I50 Heart failure
0.827 0.173 0.000
K70.0 Alcoholic fatty liver
0.826 0.174 0.000
I08 Multiple valve diseases
0.826 0.174 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.825 0.175 0.000
C25 Malignant neoplasm of pancreas
0.825 0.175 0.000
C79.2 Secondary malignant neoplasm of skin
0.824 0.176 0.000
K76.6 Portal hypertension
0.823 0.177 0.000
G25.8 Other specified extrapyramidal and movement disorders
0.821 0.179 0.000
C50 Malignant neoplasm of breast
0.818 0.182 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.817 0.183 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.815 0.185 0.000
I71 Aortic aneurysm and dissection
0.814 0.186 0.000
L53 Other erythematous conditions
0.810 0.190 0.000
K74.6 Other and unspecified cirrhosis of liver
0.809 0.191 0.000
K72 Hepatic failure, not elsewhere classified
0.809 0.191 0.000
S00-S09 Injuries to the head
0.804 0.196 0.000
I38 Endocarditis, valve unspecified
0.804 0.196 0.000
I51 Complications and ill-defined descriptions of heart disease
0.803 0.197 0.000
K59 Other functional intestinal disorders
0.801 0.199 0.000
L03.3 Cellulitis of trunk
0.801 0.199 0.000
C85.1 B-cell lymphoma, unspecified
0.801 0.199 0.000
K70.4 Alcoholic hepatic failure
0.800 0.200 0.000
I31 Other diseases of pericardium
0.798 0.202 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.798 0.202 0.000
K56.7 Ileus, unspecified
0.798 0.202 0.000
K65-K67 Diseases of peritoneum
0.798 0.202 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.796 0.204 0.000
C18.0 Caecum
0.796 0.204 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.794 0.206 0.000
H65 Nonsuppurative otitis media
0.793 0.207 0.000
C18.1 Appendix
0.789 0.211 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.789 0.211 0.000
I85 Oesophageal varices
0.787 0.213 0.000
K82.8 Other specified diseases of gallbladder
0.786 0.214 0.000
T86 Failure and rejection of transplanted organs and tissues
0.785 0.215 0.000
D00-D09 In situ neoplasms
0.785 0.215 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.780 0.220 0.000
K75 Other inflammatory liver diseases
0.779 0.221 0.000
K63 Other diseases of intestine
0.779 0.221 0.000
C18.9 Colon, unspecified
0.777 0.223 0.000
H80-H83 Diseases of inner ear
0.775 0.225 0.000
I80 Phlebitis and thrombophlebitis
0.775 0.225 0.000
C18.5 Splenic flexure
0.774 0.226 0.000
S10-S19 Injuries to the neck
0.774 0.226 0.000
I08.0 Disorders of both mitral and aortic valves
0.772 0.228 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.771 0.229 0.000
I73.8 Other specified peripheral vascular diseases
0.771 0.229 0.000
D60-D64 Aplastic and other anaemias
0.769 0.231 0.000
C50.8 Overlapping lesion of breast
0.769 0.231 0.000
I42.8 Other cardiomyopathies
0.765 0.235 0.000
G93 Other disorders of brain
0.763 0.237 0.000
S50-S59 Injuries to the elbow and forearm
0.763 0.237 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.763 0.237 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.762 0.238 0.000
K92.9 Disease of digestive system, unspecified
0.760 0.240 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.760 0.240 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.760 0.240 0.000
I45.6 Preexcitation syndrome
0.759 0.241 0.000
I34.1 Mitral (valve) prolapse
0.757 0.243 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.756 0.244 0.000
L03.8 Cellulitis of other sites
0.754 0.246 0.000
C18.6 Descending colon
0.753 0.247 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.753 0.247 0.000
K85.9 Acute pancreatitis, unspecified
0.752 0.248 0.000
L40-L45 Papulosquamous disorders
0.751 0.249 0.000
R25.3 Fasciculation
0.750 0.250 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.749 0.251 0.000
R53 Malaise and fatigue
0.748 0.252 0.000
C91 Lymphoid leukaemia
0.747 0.253 0.000
Chapter XX External causes of morbidity and mortality
0.747 0.253 0.000
R73 Elevated blood glucose level
0.746 0.254 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.742 0.258 0.000
I74 Arterial embolism and thrombosis
0.742 0.258 0.000
R61 Hyperhidrosis
0.742 0.258 0.000
S20-S29 Injuries to the thorax
0.741 0.259 0.000
K76.9 Liver disease, unspecified
0.741 0.259 0.000
H69 Other disorders of Eustachian tube
0.741 0.259 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.740 0.259 0.000
R63.3 Feeding difficulties and mismanagement
0.740 0.260 0.000
K59.0 Constipation
0.739 0.261 0.000
K83.8 Other specified diseases of biliary tract
0.737 0.263 0.000
L53.9 Erythematous condition, unspecified
0.737 0.263 0.000
L05 Pilonidal cyst
0.737 0.263 0.000
K86 Other diseases of pancreas
0.736 0.264 0.000
R50.8 Other specified fever
0.735 0.265 0.000
I87 Other disorders of veins
0.733 0.267 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.732 0.268 0.000
I37 Pulmonary valve disorders
0.731 0.269 0.000
K74.3 Primary biliary cirrhosis
0.729 0.270 0.000
R27 Other lack of coordination
0.727 0.273 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.727 0.273 0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.726 0.274 0.000
R57.2 Septic shock
0.726 0.274 0.000
I47.1 Supraventricular tachycardia
0.726 0.274 0.000
I33 Acute and subacute endocarditis
0.724 0.276 0.000
K70.9 Alcoholic liver disease, unspecified
0.724 0.276 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.723 0.277 0.000
R68.8 Other specified general symptoms and signs
0.723 0.277 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.723 0.277 0.000
G25.0 Essential tremor
0.722 0.278 0.000
G20 Parkinson's disease
0.722 0.278 0.000
T87.4 Infection of amputation stump
0.721 0.279 0.000
H66 Suppurative and unspecified otitis media
0.721 0.279 0.000
Chapter V Mental and behavioural disorders
0.721 0.279 0.000
C50.4 Upper-outer quadrant of breast
0.720 0.280 0.000
C16 Malignant neoplasm of stomach
0.719 0.281 0.000
H65.3 Chronic mucoid otitis media
0.718 0.282 0.000
C83.0 Small cell (diffuse)
0.718 0.282 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.716 0.283 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.716 0.284 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.716 0.284 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.715 0.284 0.000
C17 Malignant neoplasm of small intestine
0.715 0.284 0.000
C23 Malignant neoplasm of gallbladder
0.715 0.284 0.000
K77 Liver disorders in diseases classified elsewhere
0.715 0.284 0.000
K73 Chronic hepatitis, not elsewhere classified
0.715 0.284 0.000
K71 Toxic liver disease
0.715 0.284 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.715 0.285 0.000
C21 Malignant neoplasm of anus and anal canal
0.714 0.286 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.714 0.286 0.000
R23 Other skin changes
0.713 0.287 0.000
I72 Other aneurysm
0.713 0.287 0.000
K74.5 Biliary cirrhosis, unspecified
0.712 0.288 0.000
R59 Enlarged lymph nodes
0.711 0.289 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.711 0.289 0.000
R62 Lack of expected normal physiological development
0.711 0.289 0.000
C18.4 Transverse colon
0.710 0.290 0.000
C20 Malignant neoplasm of rectum
0.710 0.290 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.710 0.290 0.000
I52 Other heart disorders in diseases classified elsewhere
0.709 0.290 0.000
I48 Atrial fibrillation and flutter
0.709 0.290 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.709 0.290 0.000
I41 Myocarditis in diseases classified elsewhere
0.709 0.290 0.000
I40 Acute myocarditis
0.709 0.290 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.709 0.290 0.000
I36 Nonrheumatic tricuspid valve disorders
0.709 0.290 0.000
I32 Pericarditis in diseases classified elsewhere
0.709 0.290 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.707 0.293 0.000
S70-S79 Injuries to the hip and thigh
0.707 0.293 0.000
C18.8 Overlapping lesion of colon
0.705 0.294 0.000
S01 Open wound of head
0.705 0.295 0.000
H74 Other disorders of middle ear and mastoid
0.705 0.295 0.000
K83.1 Obstruction of bile duct
0.705 0.295 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.703 0.297 0.000
C50.5 Lower-outer quadrant of breast
0.703 0.297 0.000
H83 Other diseases of inner ear
0.702 0.298 0.000
S90-S99 Injuries to the ankle and foot
0.702 0.298 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.701 0.299 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.700 0.300 0.000
K56.6 Other and unspecified intestinal obstruction
0.699 0.301 0.000
R21 Rash and other nonspecific skin eruption
0.699 0.301 0.000
L10-L14 Bullous disorders
0.699 0.301 0.000
K70.2 Alcoholic fibrosis and sclerosis of liver
0.699 0.301 0.000
R63.5 Abnormal weight gain
0.698 0.302 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.698 0.302 0.000
R29.4 Clicking hip
0.698 0.302 0.000
R29.3 Abnormal posture
0.698 0.302 0.000
R29.2 Abnormal reflex
0.698 0.302 0.000
R29.1 Meningismus
0.698 0.302 0.000
R29.0 Tetany
0.698 0.302 0.000
I50.9 Heart failure, unspecified
0.698 0.302 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.697 0.303 0.000
K92.8 Other specified diseases of digestive system
0.697 0.303 0.000
K70.1 Alcoholic hepatitis
0.697 0.303 0.000
L04 Acute lymphadenitis
0.696 0.304 0.000
L01 Impetigo
0.696 0.304 0.000
L00 Staphylococcal scalded skin syndrome
0.696 0.304 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.696 0.304 0.000
H60-H62 Diseases of external ear
0.695 0.305 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.694 0.306 0.000
I42.6 Alcoholic cardiomyopathy
0.694 0.306 0.000
I42.5 Other restrictive cardiomyopathy
0.694 0.306 0.000
I42.4 Endocardial fibroelastosis
0.694 0.306 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.694 0.306 0.000
I70 Atherosclerosis
0.694 0.306 0.000
D80-D89 Certain disorders involving the immune mechanism
0.694 0.306 0.000
I88 Nonspecific lymphadenitis
0.693 0.307 0.000
C15.9 Oesophagus, unspecified
0.693 0.307 0.000
S60-S69 Injuries to the wrist and hand
0.693 0.307 0.000
L08 Other local infections of skin and subcutaneous tissue
0.691 0.309 0.000
R55 Syncope and collapse
0.691 0.309 0.000
G96 Other disorders of central nervous system
0.690 0.310 0.000
T33-T35 Frostbite
0.690 0.310 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.690 0.310 0.000
T00-T07 Injuries involving multiple body regions
0.690 0.310 0.000
I77 Other disorders of arteries and arterioles
0.690 0.310 0.000
K91.0 Vomiting following gastro-intestinal surgery
0.690 0.310 0.000
T82.1 Mechanical complication of cardiac electronic device
0.689 0.311 0.000
R58 Haemorrhage, not elsewhere classified
0.689 0.311 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.689 0.311 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.689 0.311 0.000
I99 Other and unspecified disorders of circulatory system
0.687 0.313 0.000
H73 Other disorders of tympanic membrane
0.686 0.314 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.683 0.316 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.682 0.318 0.000
C95 Leukaemia of unspecified cell type
0.682 0.318 0.000
C94 Other leukaemias of specified cell type
0.682 0.318 0.000
C93 Monocytic leukaemia
0.682 0.318 0.000
C88 Malignant immunoproliferative diseases
0.682 0.318 0.000
C86 Other specified types of T/NK-cell lymphoma
0.682 0.318 0.000
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified
0.682 0.318 0.000
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites
0.682 0.318 0.000
L02.0 Cutaneous abscess, furuncle and carbuncle of face
0.682 0.318 0.000
D68 Other coagulation defects
0.681 0.319 0.000
R73.9 Hyperglycaemia, unspecified
0.680 0.320 0.000
D69 Purpura and other haemorrhagic conditions
0.680 0.320 0.000
T87.6 Other and unspecified complications of amputation stump
0.680 0.320 0.000
I85.0 Oesophageal varices with bleeding
0.680 0.320 0.000
K75.9 Inflammatory liver disease, unspecified
0.679 0.321 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.679 0.321 0.000
C78.0 Secondary malignant neoplasm of lung
0.678 0.322 0.000
G70-G73 Diseases of myoneural junction and muscle
0.677 0.323 0.000
G24 Dystonia
0.677 0.323 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.677 0.323 0.000
G90 Disorders of autonomic nervous system
0.676 0.324 0.000
C77.8 Lymph nodes of multiple regions
0.676 0.324 0.000
G93.0 Cerebral cysts
0.675 0.325 0.000
C15.5 Lower third of oesophagus
0.675 0.325 0.000
T86.1 Kidney transplant failure and rejection
0.675 0.325 0.000
S05 Injury of eye and orbit
0.674 0.325 0.000
C25.9 Pancreas, unspecified
0.674 0.326 0.000
K55 Vascular disorders of intestine
0.673 0.327 0.000
K72.9 Hepatic failure, unspecified
0.673 0.327 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.673 0.327 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.672 0.328 0.000
I95 Hypotension
0.671 0.328 0.000
R26 Abnormalities of gait and mobility
0.671 0.329 0.000
I81 Portal vein thrombosis
0.670 0.330 0.000
Q80-Q89 Other congenital malformations
0.670 0.330 0.000
I85.9 Oesophageal varices without bleeding
0.669 0.331 0.000
R63.6 Insufficient intake of food and water due to self neglect
0.669 0.331 0.000
R63.2 Polyphagia
0.669 0.331 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.669 0.331 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.669 0.331 0.000
K63.1 Perforation of intestine (nontraumatic)
0.669 0.331 0.000
K91.4 Colostomy and enterostomy malfunction
0.668 0.332 0.000
I50.0 Congestive heart failure
0.667 0.333 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.667 0.333 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.667 0.333 0.000
T82.3 Mechanical complication of other vascular grafts
0.667 0.333 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.665 0.335 0.000
I07 Rheumatic tricuspid valve diseases
0.665 0.335 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.665 0.335 0.000
R50.2 Drug-induced fever
0.664 0.336 0.000
R50.1 Persistent fever
0.664 0.336 0.000
K65 Peritonitis
0.662 0.338 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.661 0.339 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.661 0.339 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.659 0.341 0.000
F30-F39 Mood [affective] disorders
0.658 0.342 0.000
T88.5 Other complications of anaesthesia
0.658 0.342 0.000
K63.2 Fistula of intestine
0.658 0.342 0.000
G23 Other degenerative diseases of basal ganglia
0.657 0.343 0.000
G21 Secondary Parkinsonism
0.657 0.343 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.657 0.343 0.000
G22 Parkinsonism in diseases classified elsewhere
0.657 0.343 0.000
T66-T78 Other and unspecified effects of external causes
0.657 0.343 0.000
C80 Malignant neoplasm without specification of site
0.657 0.343 0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck
0.657 0.343 0.000
R63.1 Polydipsia
0.656 0.344 0.000
I42.2 Other hypertrophic cardiomyopathy
0.655 0.345 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.655 0.345 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.654 0.346 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.654 0.346 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.653 0.347 0.000
D64 Other anaemias
0.653 0.347 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.653 0.347 0.000
Chapter XXII Codes for special purposes
0.653 0.347 0.000
L53.8 Other specified erythematous conditions
0.652 0.348 0.000
G00 Bacterial meningitis, not elsewhere classified
0.652 0.348 0.000
R25.1 Tremor, unspecified
0.652 0.348 0.000
C77.4 Inguinal and lower limb lymph nodes
0.651 0.349 0.000
K74.4 Secondary biliary cirrhosis
0.651 0.349 0.000
K74.2 Hepatic fibrosis with hepatic sclerosis
0.651 0.349 0.000
K74.1 Hepatic sclerosis
0.651 0.349 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.651 0.349 0.000
H83.0 Labyrinthitis
0.650 0.350 0.000
C51-C58 Malignant neoplasms of female genital organs
0.650 0.350 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.649 0.351 0.000
H72 Perforation of tympanic membrane
0.649 0.351 0.000
K76.7 Hepatorenal syndrome
0.649 0.351 0.000
K76.5 Hepatic veno-occlusive disease
0.649 0.351 0.000
K76.4 Peliosis hepatis
0.649 0.351 0.000
K76.3 Infarction of liver
0.649 0.351 0.000
K76.2 Central haemorrhagic necrosis of liver
0.649 0.351 0.000
K76.1 Chronic passive congestion of liver
0.649 0.351 0.000
K82.2 Perforation of gallbladder
0.649 0.351 0.000
T88.4 Failed or difficult intubation
0.648 0.352 0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified
0.647 0.353 0.000
I82 Other venous embolism and thrombosis
0.646 0.353 0.000
I30 Acute pericarditis
0.646 0.354 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.646 0.354 0.000
H70 Mastoiditis and related conditions
0.646 0.354 0.000
H68 Eustachian salpingitis and obstruction
0.646 0.354 0.000
H67 Otitis media in diseases classified elsewhere
0.646 0.354 0.000
G30-G32 Other degenerative diseases of the nervous system
0.646 0.354 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.646 0.354 0.000
I09 Other rheumatic heart diseases
0.645 0.355 0.000
I06 Rheumatic aortic valve diseases
0.645 0.355 0.000
S01.0 Open wound of scalp
0.645 0.355 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.645 0.355 0.000
I34.0 Mitral (valve) insufficiency
0.644 0.356 0.000
D05 Carcinoma in situ of breast
0.643 0.357 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.642 0.358 0.000
K85.1 Biliary acute pancreatitis
0.641 0.359 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.641 0.359 0.000
D55-D59 Haemolytic anaemias
0.640 0.360 0.000
C15.4 Middle third of oesophagus
0.639 0.361 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.638 0.362 0.000
L50 Urticaria
0.637 0.362 0.000
I78 Diseases of capillaries
0.637 0.363 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.637 0.363 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.636 0.364 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.635 0.365 0.000
L03.2 Cellulitis of face
0.635 0.365 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.634 0.366 0.000
I46 Cardiac arrest
0.634 0.366 0.000
R77 Other abnormalities of plasma proteins
0.633 0.367 0.000
I05 Rheumatic mitral valve diseases
0.633 0.367 0.000
K81.8 Other cholecystitis
0.632 0.367 0.000
C25.0 Head of pancreas
0.632 0.368 0.000
K83.0 Cholangitis
0.632 0.368 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.631 0.369 0.000
L54 Erythema in diseases classified elsewhere
0.631 0.369 0.000
L51 Erythema multiforme
0.631 0.369 0.000
L52 Erythema nodosum
0.631 0.369 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.630 0.370 0.000
H71 Cholesteatoma of middle ear
0.630 0.370 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.629 0.371 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.628 0.371 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.628 0.371 0.000
G40-G47 Episodic and paroxysmal disorders
0.628 0.372 0.000
S00 Superficial injury of head
0.628 0.372 0.000
G93.2 Benign intracranial hypertension
0.627 0.373 0.000
H69.9 Eustachian tube disorder, unspecified
0.626 0.374 0.000
K63.8 Other specified diseases of intestine
0.626 0.374 0.000
I08.8 Other multiple valve diseases
0.626 0.374 0.000
R54 Senility
0.626 0.374 0.000
I31.3 Pericardial effusion (noninflammatory)
0.626 0.374 0.000
G25.9 Extrapyramidal and movement disorder, unspecified
0.626 0.374 0.000
G25.6 Drug-induced tics and other tics of organic origin
0.626 0.374 0.000
G25.5 Other chorea
0.626 0.374 0.000
G25.4 Drug-induced chorea
0.626 0.374 0.000
G25.3 Myoclonus
0.626 0.374 0.000
G25.2 Other specified forms of tremor
0.626 0.374 0.000
G25.1 Drug-induced tremor
0.626 0.374 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.625 0.375 0.000
I51.0 Cardiac septal defect, acquired
0.625 0.375 0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.623 0.377 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.623 0.377 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.623 0.377 0.000
G92 Toxic encephalopathy
0.623 0.377 0.000
C71 Malignant neoplasm of brain
0.623 0.377 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.622 0.377 0.000
S12 Fracture of neck
0.622 0.377 0.000
D68.2 Hereditary deficiency of other clotting factors
0.622 0.378 0.000
Q00-Q07 Congenital malformations of the nervous system
0.622 0.378 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.622 0.378 0.000
K56.0 Paralytic ileus
0.622 0.378 0.000
D61 Other aplastic anaemias
0.621 0.379 0.000
K90 Intestinal malabsorption
0.621 0.379 0.000
K83.9 Disease of biliary tract, unspecified
0.620 0.380 0.000
K83.5 Biliary cyst
0.620 0.380 0.000
K83.4 Spasm of sphincter of Oddi
0.620 0.380 0.000
K83.3 Fistula of bile duct
0.620 0.380 0.000
K83.2 Perforation of bile duct
0.620 0.380 0.000
K55.0 Acute vascular disorders of intestine
0.620 0.380 0.000
C81 Hodgkin's disease
0.620 0.380 0.000
L03.0 Cellulitis of finger and toe
0.620 0.380 0.000
I31.9 Disease of pericardium, unspecified
0.619 0.381 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.618 0.382 0.000
I51.7 Cardiomegaly
0.618 0.382 0.000
I45.3 Trifascicular block
0.617 0.383 0.000
R71 Abnormality of red blood cells
0.617 0.383 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.617 0.383 0.000
S54 Injury of nerves at forearm level
0.617 0.383 0.000
L03.1 Cellulitis of other parts of limb
0.615 0.385 0.000
D09 Carcinoma in situ of other and unspecified sites
0.614 0.386 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.614 0.386 0.000
I45.1 Other and unspecified right bundle-branch block
0.614 0.386 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.614 0.386 0.000
T79.3 Post-traumatic wound infection, not elsewhere classified
0.613 0.387 0.000
D69.6 Thrombocytopenia, unspecified
0.613 0.387 0.000
R25.0 Abnormal head movements
0.612 0.388 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.612 0.388 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.612 0.388 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.612 0.388 0.000
C85.0 Lymphosarcoma
0.612 0.388 0.000
V80-V89 Other land transport accidents
0.612 0.388 0.000
K85.8 Other acute pancreatitis
0.612 0.388 0.000
K85.3 Drug-induced acute pancreatitis
0.612 0.388 0.000
K85.2 Alcohol-induced acute pancreatitis
0.612 0.388 0.000
K85.0 Idiopathic acute pancreatitis
0.612 0.388 0.000
K56.3 Gallstone ileus
0.611 0.388 0.000
C15.8 Overlapping lesion of oesophagus
0.611 0.389 0.000
C15.3 Upper third of oesophagus
0.611 0.389 0.000
C15.2 Abdominal part of oesophagus
0.611 0.389 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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