TreeWAS – Variant ID: rs115089939

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
# Top node	1.000	0.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.999	0.001	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.993	0.007	0.000
Chapter IX Diseases of the circulatory system	0.990	0.010	0.000
Chapter X Diseases of the respiratory system	0.990	0.010	0.000
Chapter XX External causes of morbidity and mortality	0.989	0.011	0.000
M20-M25 Other joint disorders	0.988	0.012	0.000
I30-I52 Other forms of heart disease	0.981	0.019	0.000
Chapter V Mental and behavioural disorders	0.978	0.022	0.000
M25 Other joint disorders, not elsewhere classified	0.977	0.023	0.000
J30-J39 Other diseases of upper respiratory tract	0.968	0.032	0.000
M25.5 Pain in joint	0.963	0.037	0.000
I45 Other conduction disorders	0.957	0.043	0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.953	0.047	0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.948	0.052	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.942	0.058	0.000
J40-J47 Chronic lower respiratory diseases	0.941	0.059	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.940	0.060	0.000
M70-M79 Other soft tissue disorders	0.940	0.060	0.000
S60-S69 Injuries to the wrist and hand	0.939	0.061	0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.935	0.065	0.000
Chapter XXI Factors influencing health status and contact with health services	0.935	0.065	0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.933	0.067	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.928	0.072	0.000
Y83.8 Other surgical procedures	0.925	0.075	0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.917	0.083	0.000
M79 Other soft tissue disorders, not elsewhere classified	0.917	0.083	0.000
Z95 Presence of cardiac and vascular implants and grafts	0.914	0.086	0.000
J44 Other chronic obstructive pulmonary disease	0.912	0.088	0.000
I20-I25 Ischaemic heart diseases	0.912	0.088	0.000
F10 Mental and behavioural disorders due to use of alcohol	0.912	0.088	0.000
Z95.5 Presence of coronary angioplasty implant and graft	0.908	0.092	0.000
I45.1 Other and unspecified right bundle-branch block	0.906	0.094	0.000
M79.6 Pain in limb	0.900	0.100	0.000
S80-S89 Injuries to the knee and lower leg	0.895	0.105	0.000
M79.66 Pain in limb (Lower leg)	0.888	0.112	0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.885	0.115	0.000
O60-O75 Complications of labour and delivery	0.883	0.117	0.000
I27 Other pulmonary heart diseases	0.882	0.118	0.000
M25.56 Pain in joint (Lower leg)	0.880	0.120	0.000
S00-S09 Injuries to the head	0.874	0.126	0.000
I25 Chronic ischaemic heart disease	0.868	0.132	0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.867	0.133	0.000
Chapter I Certain infectious and parasitic diseases	0.865	0.135	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.864	0.136	0.000
F30-F39 Mood [affective] disorders	0.863	0.137	0.000
I35 Nonrheumatic aortic valve disorders	0.853	0.147	0.000
M35 Other systemic involvement of connective tissue	0.853	0.147	0.000
I51 Complications and ill-defined descriptions of heart disease	0.849	0.151	0.000
M25.57 Pain in joint (Ankle and foot)	0.844	0.156	0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.844	0.156	0.000
F10.2 Dependence syndrome	0.843	0.157	0.000
I25.2 Old myocardial infarction	0.838	0.162	0.000
Z88.1 Personal history of allergy to other antibiotic agents	0.834	0.166	0.000
J38.3 Other diseases of vocal cords	0.832	0.168	0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.830	0.170	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.830	0.170	0.000
T81 Complications of procedures, not elsewhere classified	0.827	0.173	0.000
J38.2 Nodules of vocal cords	0.826	0.174	0.000
I27.2 Other secondary pulmonary hypertension	0.824	0.176	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.823	0.177	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.822	0.178	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.819	0.181	0.000
M25.51 Pain in joint (Shoulder region)	0.814	0.186	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.812	0.188	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.808	0.192	0.000
S61 Open wound of wrist and hand	0.806	0.194	0.000
I45.8 Other specified conduction disorders	0.802	0.198	0.000
F10.0 Acute intoxication	0.798	0.202	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.798	0.202	0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.796	0.204	0.000
J44.8 Other specified chronic obstructive pulmonary disease	0.794	0.206	0.000
Z88.6 Personal history of allergy to analgesic agent	0.793	0.207	0.000
Z95.2 Presence of prosthetic heart valve	0.793	0.207	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.791	0.209	0.000
J38.7 Other diseases of larynx	0.791	0.209	0.000
M20 Acquired deformities of fingers and toes	0.790	0.210	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.790	0.210	0.000
I49 Other cardiac arrhythmias	0.789	0.211	0.000
J38.1 Polyp of vocal cord and larynx	0.787	0.213	0.000
S01 Open wound of head	0.784	0.216	0.000
J42 Unspecified chronic bronchitis	0.784	0.216	0.000
I21 Acute myocardial infarction	0.781	0.219	0.000
S20-S29 Injuries to the thorax	0.778	0.222	0.000
M25.4 Effusion of joint	0.776	0.224	0.000
X60-X84 Intentional self-harm	0.775	0.225	0.000
M25.59 Pain in joint (Site unspecified)	0.774	0.226	0.000
J33 Nasal polyp	0.773	0.227	0.000
I45.9 Conduction disorder, unspecified	0.772	0.228	0.000
Z37 Outcome of delivery	0.771	0.229	0.000
F32 Depressive episode	0.767	0.233	0.000
J30 Vasomotor and allergic rhinitis	0.766	0.234	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.766	0.234	0.000
B95-B98 Bacterial, viral and other infectious agents	0.765	0.234	0.000
O63 Long labour	0.763	0.237	0.000
J60-J70 Lung diseases due to external agents	0.763	0.237	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.763	0.237	0.000
M25.55 Pain in joint (Pelvic region and thigh)	0.763	0.237	0.000
O68 Labour and delivery complicated by foetal stress [distress]	0.760	0.240	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	0.760	0.240	0.000
F60-F69 Disorders of adult personality and behaviour	0.759	0.240	0.000
M25.7 Osteophyte	0.758	0.242	0.000
Z97 Presence of other devices	0.754	0.246	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.754	0.246	0.000
W00-W19 Falls	0.753	0.247	0.000
T81.4 Infection following a procedure, not elsewhere classified	0.750	0.250	0.000
I38 Endocarditis, valve unspecified	0.750	0.250	0.000
J36 Peritonsillar abscess	0.749	0.251	0.000
M21 Other acquired deformities of limbs	0.748	0.252	0.000
S70-S79 Injuries to the hip and thigh	0.747	0.253	0.000
I31 Other diseases of pericardium	0.746	0.254	0.000
F10.3 Withdrawal state	0.745	0.255	0.000
Y45.0 Opioids and related analgesics	0.743	0.256	0.000
J38.4 Oedema of larynx	0.743	0.257	0.000
J35 Chronic diseases of tonsils and adenoids	0.743	0.257	0.000
W20-W49 Exposure to inanimate mechanical forces	0.741	0.259	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.738	0.262	0.000
J40 Bronchitis, not specified as acute or chronic	0.737	0.263	0.000
I27.0 Primary pulmonary hypertension	0.737	0.263	0.000
S60 Superficial injury of wrist and hand	0.737	0.263	0.000
I35.0 Aortic (valve) stenosis	0.736	0.264	0.000
I33 Acute and subacute endocarditis	0.735	0.265	0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified	0.734	0.265	0.000
M79.0 Rheumatism, unspecified	0.734	0.266	0.000
I46 Cardiac arrest	0.733	0.267	0.000
Y83.4 Other reconstructive surgery	0.732	0.267	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.731	0.268	0.000
M35.3 Polymyalgia rheumatica	0.730	0.270	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.728	0.272	0.000
S82 Fracture of lower leg, including ankle	0.727	0.273	0.000
M22 Disorders of patella	0.725	0.275	0.000
S50-S59 Injuries to the elbow and forearm	0.719	0.281	0.000
M65-M68 Disorders of synovium and tendon	0.719	0.281	0.000
I51.7 Cardiomegaly	0.718	0.282	0.000
Z83 Family history of other specific disorders	0.718	0.282	0.000
M79.69 Pain in limb (Site unspecified)	0.717	0.282	0.000
J00-J06 Acute upper respiratory infections	0.717	0.283	0.000
Chapter XXII Codes for special purposes	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
O70 Perineal laceration during delivery	0.717	0.283	0.000
T79-T79 Certain early complications of trauma	0.716	0.284	0.000
T33-T35 Frostbite	0.716	0.284	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.716	0.284	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.716	0.284	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.716	0.284	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.716	0.284	0.000
T00-T07 Injuries involving multiple body regions	0.716	0.284	0.000
S10-S19 Injuries to the neck	0.716	0.284	0.000
M05-M14 Inflammatory polyarthropathies	0.715	0.285	0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.715	0.285	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.713	0.287	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.713	0.287	0.000
M31 Other necrotising vasculopathies	0.713	0.287	0.000
I45.6 Preexcitation syndrome	0.713	0.287	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.712	0.288	0.000
M91-M94 Chondropathies	0.712	0.288	0.000
M60-M63 Disorders of muscles	0.712	0.288	0.000
M00-M03 Infectious arthropathies	0.712	0.288	0.000
S90-S99 Injuries to the ankle and foot	0.712	0.288	0.000
I00-I02 Acute rheumatic fever	0.710	0.290	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.709	0.291	0.000
Y35-Y36 Legal intervention and operations of war	0.709	0.291	0.000
Y10-Y34 Event of undetermined intent	0.709	0.291	0.000
Y00-Y09 Assault	0.709	0.291	0.000
X85-X99 Assault	0.709	0.291	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.709	0.291	0.000
X50-X57 Overexertion, travel and privation	0.709	0.291	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.709	0.291	0.000
X30-X39 Exposure to forces of nature	0.709	0.291	0.000
X20-X29 Contact with venomous animals and plants	0.709	0.291	0.000
X10-X19 Contact with heat and hot substances	0.709	0.291	0.000
X00-X09 Exposure to smoke, fire and flames	0.709	0.291	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.709	0.291	0.000
W75-W84 Other accidental threats to breathing	0.709	0.291	0.000
W65-W74 Accidental drowning and submersion	0.709	0.291	0.000
W50-W64 Exposure to animate mechanical forces	0.709	0.291	0.000
V98-V99 Other and unspecified transport accidents	0.709	0.291	0.000
V95-V97 Air and space transport accidents	0.709	0.291	0.000
V90-V94 Water transport accidents	0.709	0.291	0.000
V80-V89 Other land transport accidents	0.709	0.291	0.000
V70-V79 Bus occupant injured in transport accident	0.709	0.291	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.709	0.291	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.709	0.291	0.000
V40-V49 Car occupant injured in transport accident	0.709	0.291	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.709	0.291	0.000
V20-V29 Motorcycle rider injured in transport accident	0.709	0.291	0.000
V01-V09 Pedestrian injured in transport accident	0.709	0.291	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.709	0.291	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.709	0.291	0.000
M34 Systemic sclerosis	0.709	0.291	0.000
M33 Dermatopolymyositis	0.709	0.291	0.000
M32 Systemic lupus erythematosus	0.709	0.291	0.000
M30 Polyarteritis nodosa and related conditions	0.709	0.291	0.000
M24 Other specific joint derangements	0.709	0.291	0.000
M40-M43 Deforming dorsopathies	0.708	0.292	0.000
O00-O08 Pregnancy with abortive outcome	0.708	0.292	0.000
F32.2 Severe depressive episode without psychotic symptoms	0.706	0.294	0.000
V10-V19 Pedal cyclist injured in transport accident	0.704	0.296	0.000
I52 Other heart disorders in diseases classified elsewhere	0.704	0.296	0.000
I48 Atrial fibrillation and flutter	0.704	0.296	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.704	0.296	0.000
I41 Myocarditis in diseases classified elsewhere	0.704	0.296	0.000
I40 Acute myocarditis	0.704	0.296	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.704	0.296	0.000
I37 Pulmonary valve disorders	0.704	0.296	0.000
I36 Nonrheumatic tricuspid valve disorders	0.704	0.296	0.000
I32 Pericarditis in diseases classified elsewhere	0.704	0.296	0.000
I30 Acute pericarditis	0.704	0.296	0.000
J95-J99 Other diseases of the respiratory system	0.703	0.297	0.000
I05-I09 Chronic rheumatic heart diseases	0.703	0.297	0.000
Y95 Nosocomial condition	0.702	0.298	0.000
I34 Nonrheumatic mitral valve disorders	0.702	0.298	0.000
F99-F99 Unspecified mental disorder	0.701	0.299	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.701	0.299	0.000
F80-F89 Disorders of psychological development	0.701	0.299	0.000
F70-F79 Mental retardation	0.701	0.299	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.701	0.299	0.000
M25.9 Joint disorder, unspecified	0.701	0.299	0.000
M25.8 Other specified joint disorders	0.701	0.299	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.701	0.299	0.000
M25.3 Other instability of joint	0.701	0.299	0.000
M25.2 Flail joint	0.701	0.299	0.000
M25.1 Fistula of joint	0.701	0.299	0.000
M25.0 Haemarthrosis	0.701	0.299	0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.700	0.300	0.000
M86-M90 Other osteopathies	0.700	0.300	0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.699	0.301	0.000
Z37.0 Single live birth	0.695	0.305	0.000
J37 Chronic laryngitis and laryngotracheitis	0.694	0.306	0.000
M25.50 Pain in joint (Multiple sites)	0.693	0.306	0.000
S40-S49 Injuries to the shoulder and upper arm	0.693	0.307	0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.693	0.307	0.000
S81 Open wound of lower leg	0.693	0.307	0.000
Z88.5 Personal history of allergy to narcotic agent	0.692	0.308	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.691	0.309	0.000
M25.58 Pain in joint (Other)	0.691	0.309	0.000
M25.54 Pain in joint (Hand)	0.691	0.309	0.000
M25.53 Pain in joint (Forearm)	0.691	0.309	0.000
M25.52 Pain in joint (Upper arm)	0.691	0.309	0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.690	0.310	0.000
M72 Fibroblastic disorders	0.690	0.310	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.689	0.311	0.000
I51.9 Heart disease, unspecified	0.689	0.311	0.000
F10.1 Harmful use	0.687	0.313	0.000
Z95.4 Presence of other heart-valve replacement	0.687	0.313	0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.687	0.313	0.000
I45.5 Other specified heart block	0.686	0.314	0.000
I45.4 Nonspecific intraventricular block	0.686	0.314	0.000
I45.3 Trifascicular block	0.686	0.314	0.000
I45.2 Bifascicular block	0.686	0.314	0.000
I45.0 Right fascicular block	0.686	0.314	0.000
S06 Intracranial injury	0.686	0.314	0.000
M77 Other enthesopathies	0.685	0.315	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.684	0.316	0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.684	0.316	0.000
S62 Fracture at wrist and hand level	0.684	0.316	0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances	0.684	0.316	0.000
T66-T78 Other and unspecified effects of external causes	0.682	0.318	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.682	0.318	0.000
I44 Atrioventricular and left bundle-branch block	0.681	0.319	0.000
J38.6 Stenosis of larynx	0.680	0.320	0.000
J38.5 Laryngeal spasm	0.680	0.320	0.000
J38.0 Paralysis of vocal cords and larynx	0.680	0.320	0.000
I26 Pulmonary embolism	0.678	0.322	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.678	0.322	0.000
O63.1 Prolonged second stage (of labour)	0.677	0.323	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.677	0.323	0.000
S61.8 Open wound of other parts of wrist and hand	0.676	0.324	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.676	0.324	0.000
O85-O92 Complications predominantly related to the puerperium	0.676	0.324	0.000
J41 Simple and mucopurulent chronic bronchitis	0.674	0.326	0.000
J46 Status asthmaticus	0.674	0.326	0.000
T87 Complications peculiar to reattachment and amputation	0.674	0.326	0.000
T86 Failure and rejection of transplanted organs and tissues	0.674	0.326	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.674	0.326	0.000
M76 Enthesopathies of lower limb, excluding foot	0.674	0.326	0.000
M73 Soft tissue disorders in diseases classified elsewhere	0.674	0.326	0.000
M71 Other bursopathies	0.674	0.326	0.000
M70 Soft tissue disorders related to use, overuse and pressure	0.674	0.326	0.000
I35.9 Aortic valve disorder, unspecified	0.674	0.326	0.000
S69 Other and unspecified injuries of wrist and hand	0.673	0.327	0.000
S68 Traumatic amputation of wrist and hand	0.673	0.327	0.000
S67 Crushing injury of wrist and hand	0.673	0.327	0.000
S65 Injury of blood vessels at wrist and hand level	0.673	0.327	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.673	0.327	0.000
S61.0 Open wound of finger(s) without damage to nail	0.672	0.328	0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.672	0.328	0.000
S80 Superficial injury of lower leg	0.671	0.329	0.000
J81 Pulmonary oedema	0.671	0.329	0.000
S01.0 Open wound of scalp	0.671	0.329	0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.670	0.329	0.000
F18 Mental and behavioural disorders due to use of volatile solvents	0.670	0.329	0.000
F16 Mental and behavioural disorders due to use of hallucinogens	0.670	0.329	0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.670	0.329	0.000
F14 Mental and behavioural disorders due to use of cocaine	0.670	0.329	0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.670	0.329	0.000
F12 Mental and behavioural disorders due to use of cannabinoids	0.670	0.329	0.000
F11 Mental and behavioural disorders due to use of opioids	0.670	0.329	0.000
J43 Emphysema	0.670	0.329	0.000
J39 Other diseases of upper respiratory tract	0.670	0.330	0.000
Y83.9 Surgical procedure, unspecified	0.669	0.331	0.000
Y83.5 Amputation of limb(s)	0.669	0.331	0.000
Y83.3 Surgical operation with formation of external stoma	0.669	0.331	0.000
Y83.0 Surgical operation with transplant of whole organ	0.669	0.331	0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system	0.668	0.332	0.000
Z85 Personal history of malignant neoplasm	0.668	0.332	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.666	0.334	0.000
J33.0 Polyp of nasal cavity	0.666	0.334	0.000
T85.4 Mechanical complication of breast prosthesis and implant	0.666	0.334	0.000
I28 Other diseases of pulmonary vessels	0.666	0.334	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.665	0.334	0.000
O47 False labour	0.665	0.335	0.000
J34 Other disorders of nose and nasal sinuses	0.665	0.335	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.665	0.335	0.000
Y52 Agents primarily affecting the cardiovascular system	0.663	0.337	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.663	0.337	0.000
M35.0 Sicca syndrome [Sjogren]	0.663	0.337	0.000
M20.4 Other hammer toe(s) (acquired)	0.663	0.337	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.662	0.338	0.000
F33 Recurrent depressive disorder	0.662	0.338	0.000
M80-M85 Disorders of bone density and structure	0.661	0.339	0.000
A30-A49 Other bacterial diseases	0.661	0.339	0.000
S02 Fracture of skull and facial bones	0.660	0.340	0.000
Y83.6 Removal of other organ (partial) (total)	0.660	0.340	0.000
B25-B34 Other viral diseases	0.660	0.340	0.000
I22 Subsequent myocardial infarction	0.659	0.340	0.000
J09-J18 Influenza and pneumonia	0.659	0.340	0.000
Z89 Acquired absence of limb	0.657	0.343	0.000
Z84 Family history of other conditions	0.657	0.343	0.000
Z81 Family history of mental and behavioural disorders	0.657	0.343	0.000
M79.9 Soft tissue disorder, unspecified	0.657	0.343	0.000
M79.5 Residual foreign body in soft tissue	0.657	0.343	0.000
M79.4 Hypertrophy of (infrapatellar) fat pad	0.657	0.343	0.000
M79.3 Panniculitis, unspecified	0.657	0.343	0.000
M79.2 Neuralgia and neuritis, unspecified	0.657	0.343	0.000
M79.1 Myalgia	0.657	0.343	0.000
I49.9 Cardiac arrhythmia, unspecified	0.657	0.343	0.000
Z95.3 Presence of xenogenic heart valve	0.655	0.345	0.000
I23 Certain current complications following acute myocardial infarction	0.654	0.346	0.000
F10.9 Unspecified mental and behavioural disorder	0.654	0.346	0.000
F10.8 Other mental and behavioural disorders	0.654	0.346	0.000
F10.7 Residual and late-onset psychotic disorder	0.654	0.346	0.000
F10.6 Amnesic syndrome	0.654	0.346	0.000
F10.5 Psychotic disorder	0.654	0.346	0.000
F10.4 Withdrawal state with delirium	0.654	0.346	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.653	0.347	0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.652	0.348	0.000
M23 Internal derangement of knee	0.652	0.348	0.000
S64 Injury of nerves at wrist and hand level	0.652	0.348	0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.651	0.349	0.000
I50 Heart failure	0.650	0.350	0.000
T81.3 Disruption of operation wound, not elsewhere classified	0.649	0.351	0.000
Z37.2 Twins, both liveborn	0.647	0.353	0.000
Z90 Acquired absence of organs, not elsewhere classified	0.647	0.353	0.000
Y44 Agents primarily affecting blood constituents	0.646	0.354	0.000
M79.68 Pain in limb (Other)	0.645	0.355	0.000
M79.64 Pain in limb (Hand)	0.645	0.355	0.000
M79.63 Pain in limb (Forearm)	0.645	0.355	0.000
M79.62 Pain in limb (Upper arm)	0.645	0.355	0.000
M79.61 Pain in limb (Shoulder region)	0.645	0.355	0.000
M79.60 Pain in limb (Multiple sites)	0.645	0.355	0.000
Z88.0 Personal history of allergy to penicillin	0.645	0.355	0.000
S01.8 Open wound of other parts of head	0.645	0.355	0.000
M45-M49 Spondylopathies	0.644	0.356	0.000
O64 Obstructed labour due to malposition and malpresentation of foetus	0.643	0.357	0.000
Z94 Transplanted organ and tissue status	0.643	0.357	0.000
Z88.4 Personal history of allergy to anaesthetic agent	0.642	0.357	0.000
S89 Other and unspecified injuries of lower leg	0.642	0.358	0.000
S88 Traumatic amputation of lower leg	0.642	0.358	0.000
S87 Crushing injury of lower leg	0.642	0.358	0.000
S86 Injury of muscle and tendon at lower leg level	0.642	0.358	0.000
S85 Injury of blood vessels at lower leg level	0.642	0.358	0.000
S84 Injury of nerves at lower leg level	0.642	0.358	0.000
Z33 Pregnant state, incidental	0.642	0.358	0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.641	0.359	0.000
Z88.2 Personal history of allergy to sulphonamides	0.640	0.359	0.000
Z70-Z76 Persons encountering health services in other circumstances	0.640	0.360	0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.638	0.361	0.000
O43 Placental disorders	0.637	0.363	0.000
I21.4 Acute subendocardial myocardial infarction	0.636	0.364	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.636	0.364	0.000
Z88.7 Personal history of allergy to serum and vaccine	0.634	0.366	0.000
Z88.3 Personal history of allergy to other anti-infective agents	0.634	0.366	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.633	0.367	0.000
O74 Complications of anaesthesia during labour and delivery	0.633	0.367	0.000
O73 Retained placenta and membranes, without haemorrhage	0.633	0.367	0.000
O71 Other obstetric trauma	0.633	0.367	0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.633	0.367	0.000
O66 Other obstructed labour	0.633	0.367	0.000
O65 Obstructed labour due to maternal pelvic abnormality	0.633	0.367	0.000
O62 Abnormalities of forces of labour	0.633	0.367	0.000
O61 Failed induction of labour	0.633	0.367	0.000
O60 Preterm delivery	0.633	0.367	0.000
M79.7 Fibromyalgia	0.633	0.367	0.000
I27.9 Pulmonary heart disease, unspecified	0.632	0.368	0.000
I27.8 Other specified pulmonary heart diseases	0.632	0.368	0.000
I27.1 Kyphoscoliotic heart disease	0.632	0.368	0.000
M25.46 Effusion of joint (Lower leg)	0.632	0.368	0.000
O70.0 First degree perineal laceration during delivery	0.632	0.368	0.000
I42 Cardiomyopathy	0.630	0.370	0.000
M20.3 Other deformity of hallux (acquired)	0.628	0.371	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.628	0.372	0.000
M25.74 Osteophyte (Hand)	0.628	0.372	0.000
S08 Traumatic amputation of part of head	0.627	0.373	0.000
S07 Crushing injury of head	0.627	0.373	0.000
S05 Injury of eye and orbit	0.627	0.373	0.000
S04 Injury of cranial nerves	0.627	0.373	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.627	0.373	0.000
Z97.8 Presence of other specified devices	0.627	0.373	0.000
Z39 Postpartum care and examination	0.626	0.373	0.000
Chapter VIII Diseases of the ear and mastoid process	0.625	0.374	0.001
Z36 Antenatal screening	0.623	0.376	0.000
I25.6 Silent myocardial ischaemia	0.623	0.377	0.000
I25.5 Ischaemic cardiomyopathy	0.623	0.377	0.000
I25.4 Coronary artery aneurysm	0.623	0.377	0.000
I25.3 Aneurysm of heart	0.623	0.377	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.623	0.377	0.000
J30.1 Allergic rhinitis due to pollen	0.622	0.378	0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.621	0.379	0.000
O80-O84 Delivery	0.621	0.379	0.000
B99-B99 Other infectious diseases	0.620	0.380	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.620	0.380	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.620	0.380	0.000
B65-B83 Helminthiases	0.620	0.380	0.000
B50-B64 Protozoal diseases	0.620	0.380	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.620	0.380	0.000
B15-B19 Viral hepatitis	0.620	0.380	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.620	0.380	0.000
A80-A89 Viral infections of the central nervous system	0.620	0.380	0.000
A75-A79 Rickettsioses	0.620	0.380	0.000
A70-A74 Other diseases caused by chlamydiae	0.620	0.380	0.000
A65-A69 Other spirochaetal diseases	0.620	0.380	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.620	0.380	0.000
A20-A28 Certain zoonotic bacterial diseases	0.620	0.380	0.000
A15-A19 Tuberculosis	0.620	0.380	0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.620	0.380	0.000
Y59 Other and unspecified vaccines and biological substances	0.619	0.381	0.000
Y58 Bacterial vaccines	0.619	0.381	0.000
Y57 Other and unspecified drugs and medicaments	0.619	0.381	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.619	0.381	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.619	0.381	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.619	0.381	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.619	0.381	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.619	0.381	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.619	0.381	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.619	0.381	0.000
Y48 Anaesthetics and therapeutic gases	0.619	0.381	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.619	0.381	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.619	0.381	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.619	0.381	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.619	0.381	0.000
Y40 Systemic antibiotics	0.619	0.381	0.000
F38 Other mood [affective] disorders	0.619	0.381	0.000
F34 Persistent mood [affective] disorders	0.619	0.381	0.000
F30 Manic episode	0.619	0.381	0.000
F39 Unspecified mood [affective] disorder	0.619	0.381	0.000
M79.65 Pain in limb (Pelvic region and thigh)	0.619	0.381	0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.619	0.381	0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.618	0.382	0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.617	0.383	0.000
T84.0 Mechanical complication of internal joint prosthesis	0.615	0.384	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.615	0.385	0.000
S29 Other and unspecified injuries of thorax	0.613	0.387	0.000
I35.8 Other aortic valve disorders	0.612	0.388	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.612	0.388	0.000
M35.8 Other specified systemic involvement of connective tissue	0.612	0.388	0.000
M35.7 Hypermobility syndrome	0.612	0.388	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.612	0.388	0.000
M35.5 Multifocal fibrosclerosis	0.612	0.388	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.612	0.388	0.000
M35.2 Behcet's disease	0.612	0.388	0.000
M35.1 Other overlap syndromes	0.612	0.388	0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.610	0.390	0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.609	0.391	0.000
I51.6 Cardiovascular disease, unspecified	0.609	0.391	0.000
I51.5 Myocardial degeneration	0.609	0.391	0.000
I51.4 Myocarditis, unspecified	0.609	0.391	0.000
I51.3 Intracardiac thrombosis, not elsewhere classified	0.609	0.391	0.000
I51.2 Rupture of papillary muscle, not elsewhere classified	0.609	0.391	0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.609	0.391	0.000
I51.0 Cardiac septal defect, acquired	0.609	0.391	0.000
F31 Bipolar affective disorder	0.608	0.392	0.000
J84 Other interstitial pulmonary diseases	0.605	0.394	0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified	0.605	0.395	0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities	0.605	0.395	0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue	0.605	0.395	0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases	0.605	0.395	0.000
Z82.2 Family history of deafness and hearing loss	0.605	0.395	0.000
Z82.1 Family history of blindness and visual loss	0.605	0.395	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.605	0.395	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.604	0.396	0.000
O30 Multiple gestation	0.603	0.397	0.000
F60 Specific personality disorders	0.603	0.397	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.602	0.398	0.000
I31.9 Disease of pericardium, unspecified	0.602	0.398	0.000
S00 Superficial injury of head	0.601	0.399	0.000
J69 Pneumonitis due to solids and liquids	0.601	0.399	0.000
Z95.1 Presence of aortocoronary bypass graft	0.600	0.400	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.600	0.400	0.000
R41 Other symptoms and signs involving cognitive functions and awareness	0.595	0.405	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations