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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs115244944
log Bayes Factor = 18.0031
Chromosome 1   position 5,826,134  (GRCh37) Explore rs115244944 on Ensembl!
Variant rs115244944 is part of Cluster X0005

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.998 0.002 0.000
M05-M14 Inflammatory polyarthropathies
0.998 0.002 0.000
I30-I52 Other forms of heart disease
0.997 0.003 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.994 0.006 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.992 0.008 0.000
E11 Non-insulin-dependent diabetes mellitus
0.989 0.011 0.000
M06 Other rheumatoid arthritis
0.989 0.011 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.982 0.018 0.000
Chapter I Certain infectious and parasitic diseases
0.981 0.019 0.000
Z88.6 Personal history of allergy to analgesic agent
0.981 0.019 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.978 0.022 0.000
E10 Insulin-dependent diabetes mellitus
0.977 0.023 0.000
E11.9 Without complications
0.974 0.026 0.000
M06.9 Rheumatoid arthritis, unspecified
0.974 0.026 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.973 0.027 0.000
J95-J99 Other diseases of the respiratory system
0.969 0.031 0.000
Chapter VII Diseases of the eye and adnexa
0.969 0.031 0.000
I50 Heart failure
0.964 0.036 0.000
I20-I25 Ischaemic heart diseases
0.963 0.037 0.000
Z45 Adjustment and management of implanted device
0.951 0.049 0.000
J90-J94 Other diseases of pleura
0.949 0.051 0.000
J98 Other respiratory disorders
0.947 0.053 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.944 0.056 0.000
Z53.8 Procedure not carried out for other reasons
0.937 0.063 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.928 0.072 0.000
A30-A49 Other bacterial diseases
0.924 0.076 0.000
J30-J39 Other diseases of upper respiratory tract
0.918 0.082 0.000
Chapter XX External causes of morbidity and mortality
0.918 0.082 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.917 0.083 0.000
I10-I15 Hypertensive diseases
0.915 0.085 0.000
J00-J06 Acute upper respiratory infections
0.913 0.087 0.000
I50.0 Congestive heart failure
0.913 0.087 0.000
E14 Unspecified diabetes mellitus
0.913 0.087 0.000
S20-S29 Injuries to the thorax
0.912 0.088 0.000
E20-E35 Disorders of other endocrine glands
0.910 0.090 0.000
I42 Cardiomyopathy
0.909 0.091 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.907 0.093 0.000
M20-M25 Other joint disorders
0.907 0.093 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.906 0.094 0.000
H53-H54 Visual disturbances and blindness
0.897 0.103 0.000
B35-B49 Mycoses
0.894 0.106 0.000
J98.1 Pulmonary collapse
0.889 0.111 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.888 0.112 0.000
J40-J47 Chronic lower respiratory diseases
0.887 0.113 0.000
I20 Angina pectoris
0.884 0.116 0.000
Z51 Other medical care
0.882 0.118 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.882 0.118 0.000
M13 Other arthritis
0.880 0.120 0.000
M05 Seropositive rheumatoid arthritis
0.877 0.123 0.000
J09-J18 Influenza and pneumonia
0.874 0.126 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.871 0.129 0.000
I47 Paroxysmal tachycardia
0.871 0.129 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.870 0.130 0.000
M06.0 Seronegative rheumatoid arthritis
0.869 0.131 0.000
I50.9 Heart failure, unspecified
0.867 0.133 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.867 0.133 0.000
M70-M79 Other soft tissue disorders
0.863 0.137 0.000
Chapter VIII Diseases of the ear and mastoid process
0.863 0.137 0.000
E10.3 With ophthalmic complications
0.862 0.138 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.859 0.141 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.849 0.151 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.848 0.152 0.000
A49 Bacterial infection of unspecified site
0.847 0.152 0.000
Z80 Family history of malignant neoplasm
0.846 0.154 0.000
Chapter XI Diseases of the digestive system
0.846 0.154 0.000
Chapter XXII Codes for special purposes
0.845 0.155 0.000
S40-S49 Injuries to the shoulder and upper arm
0.843 0.157 0.000
J90 Pleural effusion, not elsewhere classified
0.841 0.159 0.000
Z45.1 Adjustment and management of infusion pump
0.838 0.162 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.836 0.163 0.000
Z97 Presence of other devices
0.835 0.164 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.835 0.165 0.000
Z86 Personal history of certain other diseases
0.834 0.166 0.000
B37 Candidiasis
0.832 0.168 0.000
E10.9 Without complications
0.832 0.168 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.828 0.172 0.000
Z94 Transplanted organ and tissue status
0.827 0.173 0.000
I12 Hypertensive renal disease
0.825 0.175 0.000
E11.4 With neurological complications
0.824 0.175 0.000
Z51.3 Blood transfusion without reported diagnosis
0.824 0.176 0.000
E14.9 Without complications
0.823 0.177 0.000
S80-S89 Injuries to the knee and lower leg
0.823 0.177 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.817 0.183 0.000
S60-S69 Injuries to the wrist and hand
0.816 0.184 0.000
Chapter VI Diseases of the nervous system
0.816 0.184 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.813 0.187 0.000
J93 Pneumothorax
0.810 0.190 0.000
I49 Other cardiac arrhythmias
0.808 0.192 0.000
I95 Hypotension
0.808 0.192 0.000
Z89 Acquired absence of limb
0.808 0.192 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.806 0.194 0.000
I46 Cardiac arrest
0.806 0.194 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.805 0.195 0.000
E10.5 With peripheral circulatory complications
0.804 0.196 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.803 0.197 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.803 0.197 0.000
E10.1 With ketoacidosis
0.801 0.199 0.000
J06.9 Acute upper respiratory infection, unspecified
0.801 0.199 0.000
I21 Acute myocardial infarction
0.801 0.199 0.000
H53 Visual disturbances
0.800 0.200 0.000
M14 Arthropathies in other diseases classified elsewhere
0.800 0.200 0.000
Z45.8 Adjustment and management of other implanted devices
0.799 0.201 0.000
D75 Other diseases of blood and blood-forming organs
0.796 0.204 0.000
Y43 Primarily systemic agents
0.796 0.204 0.000
Z92 Personal history of medical treatment
0.796 0.204 0.000
J30 Vasomotor and allergic rhinitis
0.795 0.205 0.000
I31 Other diseases of pericardium
0.793 0.206 0.000
H40-H42 Glaucoma
0.793 0.207 0.000
D70 Agranulocytosis
0.793 0.207 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.793 0.207 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.792 0.208 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.791 0.209 0.000
J44 Other chronic obstructive pulmonary disease
0.791 0.209 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.790 0.210 0.000
I44 Atrioventricular and left bundle-branch block
0.790 0.210 0.000
I20.0 Unstable angina
0.790 0.210 0.000
M07 Psoriatic and enteropathic arthropathies
0.789 0.211 0.000
M80-M85 Disorders of bone density and structure
0.788 0.212 0.000
S27 Injury of other and unspecified intrathoracic organs
0.788 0.212 0.000
E10.4 With neurological complications
0.787 0.213 0.000
B37.8 Candidiasis of other sites
0.785 0.215 0.000
Z49 Care involving dialysis
0.785 0.215 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.785 0.215 0.000
D60-D64 Aplastic and other anaemias
0.784 0.216 0.000
Z86.7 Personal history of diseases of the circulatory system
0.784 0.216 0.000
I24 Other acute ischaemic heart diseases
0.784 0.216 0.000
A41 Other septicaemia
0.783 0.217 0.000
A00-A09 Intestinal infectious diseases
0.781 0.219 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.779 0.221 0.000
E16 Other disorders of pancreatic internal secretion
0.779 0.221 0.000
Z03.8 Observation for other suspected diseases and conditions
0.778 0.222 0.000
E11.5 With peripheral circulatory complications
0.777 0.222 0.000
J32 Chronic sinusitis
0.775 0.225 0.000
Z52 Donors of organs and tissues
0.775 0.225 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.775 0.225 0.000
M13.9 Arthritis, unspecified
0.775 0.225 0.000
Z43 Attention to artificial openings
0.774 0.226 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.773 0.227 0.000
E23 Hypofunction and other disorders of pituitary gland
0.772 0.228 0.000
E40-E46 Malnutrition
0.770 0.230 0.000
H90-H95 Other disorders of ear
0.770 0.230 0.000
Z54 Convalescence
0.769 0.231 0.000
J18 Pneumonia, organism unspecified
0.768 0.232 0.000
M25 Other joint disorders, not elsewhere classified
0.767 0.233 0.000
K83 Other diseases of biliary tract
0.765 0.235 0.000
Z95.0 Presence of cardiac pacemaker
0.765 0.235 0.000
A49.0 Staphylococcal infection, unspecified
0.765 0.235 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.765 0.235 0.000
K70-K77 Diseases of liver
0.764 0.236 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.764 0.236 0.000
Z86.1 Personal history of infectious and parasitic diseases
0.763 0.237 0.000
H54 Blindness and low vision
0.763 0.237 0.000
J43 Emphysema
0.762 0.238 0.000
H55-H59 Other disorders of eye and adnexa
0.761 0.239 0.000
H10-H13 Disorders of conjunctiva
0.758 0.241 0.000
J92 Pleural plaque
0.758 0.242 0.000
E27 Other disorders of adrenal gland
0.755 0.245 0.000
J47 Bronchiectasis
0.753 0.247 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.753 0.247 0.000
I42.2 Other hypertrophic cardiomyopathy
0.752 0.248 0.000
I47.1 Supraventricular tachycardia
0.752 0.248 0.000
M11 Other crystal arthropathies
0.751 0.248 0.000
E13 Other specified diabetes mellitus
0.751 0.248 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.750 0.250 0.000
J33 Nasal polyp
0.749 0.251 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.745 0.255 0.000
I12.0 Hypertensive renal disease with renal failure
0.744 0.256 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.744 0.256 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.744 0.256 0.000
H25-H28 Disorders of lens
0.744 0.256 0.000
J98.8 Other specified respiratory disorders
0.743 0.257 0.000
L40-L45 Papulosquamous disorders
0.742 0.258 0.000
D69 Purpura and other haemorrhagic conditions
0.742 0.258 0.000
D50-D53 Nutritional anaemias
0.741 0.259 0.000
M79.6 Pain in limb
0.741 0.259 0.000
L60-L75 Disorders of skin appendages
0.740 0.260 0.000
I10 Essential (primary) hypertension
0.739 0.261 0.000
M86-M90 Other osteopathies
0.739 0.261 0.000
K86 Other diseases of pancreas
0.738 0.262 0.000
I42.8 Other cardiomyopathies
0.737 0.263 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.736 0.264 0.000
E14.3 With ophthalmic complications
0.735 0.265 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.735 0.265 0.000
M91-M94 Chondropathies
0.734 0.265 0.000
I20.9 Angina pectoris, unspecified
0.734 0.266 0.000
J60-J70 Lung diseases due to external agents
0.734 0.266 0.000
J39 Other diseases of upper respiratory tract
0.733 0.267 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.733 0.267 0.000
I25 Chronic ischaemic heart disease
0.733 0.267 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.731 0.269 0.000
O60-O75 Complications of labour and delivery
0.731 0.269 0.000
E70-E90 Metabolic disorders
0.730 0.270 0.000
Z93 Artificial opening status
0.730 0.270 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.730 0.270 0.000
Z80.3 Family history of malignant neoplasm of breast
0.729 0.271 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.729 0.271 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.728 0.272 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.726 0.274 0.000
E28 Ovarian dysfunction
0.724 0.276 0.000
M20 Acquired deformities of fingers and toes
0.724 0.276 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.723 0.277 0.000
M24 Other specific joint derangements
0.722 0.278 0.000
S70-S79 Injuries to the hip and thigh
0.722 0.278 0.000
G90-G99 Other disorders of the nervous system
0.719 0.280 0.000
Z97.4 Presence of external hearing-aid
0.719 0.281 0.000
D72 Other disorders of white blood cells
0.718 0.282 0.000
I35 Nonrheumatic aortic valve disorders
0.718 0.282 0.000
Z13 Special screening examination for other diseases and disorders
0.718 0.282 0.000
J98.4 Other disorders of lung
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
B25-B34 Other viral diseases
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.716 0.283 0.000
M60-M63 Disorders of muscles
0.716 0.283 0.000
M00-M03 Infectious arthropathies
0.716 0.283 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.717 0.283 0.000
Z84 Family history of other conditions
0.716 0.284 0.000
Z81 Family history of mental and behavioural disorders
0.716 0.284 0.000
M12 Other specific arthropathies
0.716 0.284 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.716 0.284 0.000
M08 Juvenile arthritis
0.716 0.284 0.000
M25.7 Osteophyte
0.715 0.285 0.000
E11.2 With renal complications
0.715 0.285 0.000
I52 Other heart disorders in diseases classified elsewhere
0.715 0.285 0.000
I48 Atrial fibrillation and flutter
0.715 0.285 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.715 0.285 0.000
I41 Myocarditis in diseases classified elsewhere
0.715 0.285 0.000
I40 Acute myocarditis
0.715 0.285 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.715 0.285 0.000
I37 Pulmonary valve disorders
0.715 0.285 0.000
I36 Nonrheumatic tricuspid valve disorders
0.715 0.285 0.000
I33 Acute and subacute endocarditis
0.715 0.285 0.000
I32 Pericarditis in diseases classified elsewhere
0.715 0.285 0.000
I30 Acute pericarditis
0.715 0.285 0.000
Z80.8 Family history of malignant neoplasm of other organs or systems
0.714 0.286 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.713 0.287 0.000
M65-M68 Disorders of synovium and tendon
0.713 0.287 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.713 0.287 0.000
E16.2 Hypoglycaemia, unspecified
0.713 0.287 0.000
Z44 Fitting and adjustment of external prosthetic device
0.711 0.288 0.000
M40-M43 Deforming dorsopathies
0.711 0.289 0.000
Z98 Other postsurgical states
0.711 0.289 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.710 0.290 0.000
M31 Other necrotising vasculopathies
0.709 0.290 0.000
E11.8 With unspecified complications
0.709 0.291 0.000
E11.7 With multiple complications
0.709 0.291 0.000
E11.6 With other specified complications
0.709 0.291 0.000
E11.1 With ketoacidosis
0.709 0.291 0.000
E11.0 With coma
0.709 0.291 0.000
M06.8 Other specified rheumatoid arthritis
0.709 0.291 0.000
M06.4 Inflammatory polyarthropathy
0.709 0.291 0.000
M06.3 Rheumatoid nodule
0.709 0.291 0.000
M06.2 Rheumatoid bursitis
0.709 0.291 0.000
M06.1 Adult-onset Still's disease
0.709 0.291 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.709 0.291 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.708 0.292 0.000
H53.8 Other visual disturbances
0.708 0.292 0.000
K85 Acute pancreatitis
0.707 0.293 0.000
J30.1 Allergic rhinitis due to pollen
0.707 0.293 0.000
V10-V19 Pedal cyclist injured in transport accident
0.707 0.293 0.000
J91 Pleural effusion in conditions classified elsewhere
0.706 0.293 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.706 0.294 0.000
H30-H36 Disorders of choroid and retina
0.704 0.296 0.000
T33-T35 Frostbite
0.704 0.296 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.704 0.296 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.704 0.296 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.704 0.296 0.000
T00-T07 Injuries involving multiple body regions
0.704 0.296 0.000
S10-S19 Injuries to the neck
0.704 0.296 0.000
D80-D89 Certain disorders involving the immune mechanism
0.704 0.296 0.000
B99-B99 Other infectious diseases
0.703 0.297 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.703 0.297 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.703 0.297 0.000
B65-B83 Helminthiases
0.703 0.297 0.000
B50-B64 Protozoal diseases
0.703 0.297 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.703 0.297 0.000
B15-B19 Viral hepatitis
0.703 0.297 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.703 0.297 0.000
A80-A89 Viral infections of the central nervous system
0.703 0.297 0.000
A75-A79 Rickettsioses
0.703 0.297 0.000
A70-A74 Other diseases caused by chlamydiae
0.703 0.297 0.000
A65-A69 Other spirochaetal diseases
0.703 0.297 0.000
A20-A28 Certain zoonotic bacterial diseases
0.703 0.297 0.000
A15-A19 Tuberculosis
0.703 0.297 0.000
D55-D59 Haemolytic anaemias
0.701 0.299 0.000
I49.0 Ventricular fibrillation and flutter
0.701 0.299 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.701 0.299 0.000
Z83 Family history of other specific disorders
0.701 0.299 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.701 0.299 0.000
E10.8 With unspecified complications
0.700 0.300 0.000
E10.7 With multiple complications
0.700 0.300 0.000
E10.6 With other specified complications
0.700 0.300 0.000
E10.2 With renal complications
0.700 0.300 0.000
E10.0 With coma
0.700 0.300 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.700 0.300 0.000
T79-T79 Certain early complications of trauma
0.700 0.300 0.000
I38 Endocarditis, valve unspecified
0.699 0.300 0.000
S27.0 Traumatic pneumothorax
0.699 0.300 0.000
K83.8 Other specified diseases of biliary tract
0.699 0.301 0.000
Z92.8 Personal history of other medical treatment
0.699 0.301 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.698 0.302 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.698 0.302 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.698 0.302 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.698 0.302 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.698 0.302 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.698 0.302 0.000
Y40 Systemic antibiotics
0.698 0.302 0.000
Z94.0 Kidney transplant status
0.698 0.302 0.000
H43-H45 Disorders of vitreous body and globe
0.696 0.304 0.000
I95.9 Hypotension, unspecified
0.696 0.304 0.000
W20-W49 Exposure to inanimate mechanical forces
0.696 0.304 0.000
M21 Other acquired deformities of limbs
0.696 0.304 0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
0.695 0.304 0.000
Y43.3 Other antineoplastic drugs
0.695 0.305 0.000
Z88.5 Personal history of allergy to narcotic agent
0.695 0.305 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.695 0.305 0.000
J96 Respiratory failure, not elsewhere classified
0.695 0.305 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.695 0.305 0.000
M45-M49 Spondylopathies
0.695 0.305 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.694 0.305 0.000
J34 Other disorders of nose and nasal sinuses
0.694 0.306 0.000
J93.8 Other pneumothorax
0.693 0.307 0.000
S90-S99 Injuries to the ankle and foot
0.693 0.307 0.000
I22 Subsequent myocardial infarction
0.693 0.307 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.693 0.307 0.000
M10 Gout
0.692 0.308 0.000
K82 Other diseases of gallbladder
0.692 0.308 0.000
Z87 Personal history of other diseases and conditions
0.692 0.308 0.000
I23 Certain current complications following acute myocardial infarction
0.691 0.309 0.000
J00 Acute nasopharyngitis [common cold]
0.690 0.310 0.000
A49.8 Other bacterial infections of unspecified site
0.689 0.311 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.689 0.311 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.688 0.312 0.000
M23 Internal derangement of knee
0.688 0.312 0.000
M77 Other enthesopathies
0.685 0.315 0.000
I47.2 Ventricular tachycardia
0.684 0.316 0.000
Z51.5 Palliative care
0.684 0.316 0.000
E11.3 With ophthalmic complications
0.684 0.316 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.683 0.317 0.000
I46.9 Cardiac arrest, unspecified
0.683 0.317 0.000
D68 Other coagulation defects
0.683 0.317 0.000
I80 Phlebitis and thrombophlebitis
0.683 0.317 0.000
Z45.9 Adjustment and management of unspecified implanted device
0.682 0.318 0.000
Z45.3 Adjustment and management of implanted hearing device
0.682 0.318 0.000
T66-T78 Other and unspecified effects of external causes
0.682 0.318 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.682 0.318 0.000
Z40 Prophylactic surgery
0.681 0.319 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.681 0.319 0.000
M13.0 Polyarthritis, unspecified
0.681 0.319 0.000
J94 Other pleural conditions
0.681 0.319 0.000
T93 Sequelae of injuries of lower limb
0.680 0.320 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.679 0.320 0.000
J98.9 Respiratory disorder, unspecified
0.679 0.321 0.000
J98.6 Disorders of diaphragm
0.679 0.321 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.679 0.321 0.000
J98.3 Compensatory emphysema
0.679 0.321 0.000
J98.2 Interstitial emphysema
0.679 0.321 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.678 0.322 0.000
B95-B98 Bacterial, viral and other infectious agents
0.678 0.322 0.000
K80 Cholelithiasis
0.678 0.322 0.000
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure
0.677 0.323 0.000
Z85 Personal history of malignant neoplasm
0.676 0.324 0.000
K70 Alcoholic liver disease
0.676 0.324 0.000
I34 Nonrheumatic mitral valve disorders
0.676 0.324 0.000
Z51.0 Radiotherapy session
0.675 0.325 0.000
I21.4 Acute subendocardial myocardial infarction
0.674 0.326 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.674 0.326 0.000
E23.0 Hypopituitarism
0.674 0.326 0.000
Z03.1 Observation for suspected malignant neoplasm
0.673 0.327 0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
0.673 0.327 0.000
L50-L54 Urticaria and erythema
0.672 0.328 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.672 0.328 0.000
J43.9 Emphysema, unspecified
0.671 0.328 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.671 0.329 0.000
Z89.4 Acquired absence of foot and ankle
0.671 0.329 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.671 0.329 0.000
V20-V29 Motorcycle rider injured in transport accident
0.671 0.329 0.000
L40 Psoriasis
0.670 0.330 0.000
Y44 Agents primarily affecting blood constituents
0.670 0.330 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.669 0.331 0.000
Z43.1 Attention to gastrostomy
0.669 0.331 0.000
I31.9 Disease of pericardium, unspecified
0.669 0.331 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.668 0.332 0.000
Z99.2 Dependence on renal dialysis
0.667 0.333 0.000
H40 Glaucoma
0.667 0.333 0.000
Y57 Other and unspecified drugs and medicaments
0.667 0.333 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.667 0.333 0.000
M25.77 Osteophyte (Ankle and foot)
0.667 0.333 0.000
J18.9 Pneumonia, unspecified
0.667 0.333 0.000
D61 Other aplastic anaemias
0.666 0.334 0.000
S64 Injury of nerves at wrist and hand level
0.666 0.334 0.000
Z42 Follow-up care involving plastic surgery
0.665 0.334 0.000
I95.1 Orthostatic hypotension
0.665 0.335 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.664 0.335 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.664 0.336 0.000
H00 Hordeolum and chalazion
0.664 0.336 0.000
H53.4 Visual field defects
0.664 0.336 0.000
D75.8 Other specified diseases of blood and blood-forming organs
0.664 0.336 0.000
S32 Fracture of lumbar spine and pelvis
0.663 0.337 0.000
A48 Other bacterial diseases, not elsewhere classified
0.662 0.338 0.000
A44 Bartonellosis
0.662 0.338 0.000
A43 Nocardiosis
0.662 0.338 0.000
A42 Actinomycosis
0.662 0.338 0.000
A40 Streptococcal septicaemia
0.662 0.338 0.000
A39 Meningococcal infection
0.662 0.338 0.000
A37 Whooping cough
0.662 0.338 0.000
A36 Diphtheria
0.662 0.338 0.000
A32 Listeriosis
0.662 0.338 0.000
A31 Infection due to other mycobacteria
0.662 0.338 0.000
A30 Leprosy [Hansen's disease]
0.662 0.338 0.000
A46 Erysipelas
0.662 0.338 0.000
A38 Scarlet fever
0.662 0.338 0.000
A35 Other tetanus
0.662 0.338 0.000
A34 Obstetrical tetanus
0.662 0.338 0.000
A33 Tetanus neonatorum
0.662 0.338 0.000
D73 Diseases of spleen
0.661 0.339 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.660 0.340 0.000
I42.9 Cardiomyopathy, unspecified
0.659 0.341 0.000
M14.6 Neuropathic arthropathy
0.659 0.341 0.000
S50-S59 Injuries to the elbow and forearm
0.658 0.341 0.000
J37 Chronic laryngitis and laryngotracheitis
0.658 0.342 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.658 0.342 0.000
Y35-Y36 Legal intervention and operations of war
0.658 0.342 0.000
Y10-Y34 Event of undetermined intent
0.658 0.342 0.000
Y00-Y09 Assault
0.658 0.342 0.000
X85-X99 Assault
0.658 0.342 0.000
X60-X84 Intentional self-harm
0.658 0.342 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.658 0.342 0.000
X50-X57 Overexertion, travel and privation
0.658 0.342 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.658 0.342 0.000
X30-X39 Exposure to forces of nature
0.658 0.342 0.000
X20-X29 Contact with venomous animals and plants
0.658 0.342 0.000
X10-X19 Contact with heat and hot substances
0.658 0.342 0.000
X00-X09 Exposure to smoke, fire and flames
0.658 0.342 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.658 0.342 0.000
W75-W84 Other accidental threats to breathing
0.658 0.342 0.000
W65-W74 Accidental drowning and submersion
0.658 0.342 0.000
W50-W64 Exposure to animate mechanical forces
0.658 0.342 0.000
V98-V99 Other and unspecified transport accidents
0.658 0.342 0.000
V95-V97 Air and space transport accidents
0.658 0.342 0.000
V90-V94 Water transport accidents
0.658 0.342 0.000
V80-V89 Other land transport accidents
0.658 0.342 0.000
V70-V79 Bus occupant injured in transport accident
0.658 0.342 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.658 0.342 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.658 0.342 0.000
V40-V49 Car occupant injured in transport accident
0.658 0.342 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.658 0.342 0.000
V01-V09 Pedestrian injured in transport accident
0.658 0.342 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.658 0.342 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.657 0.342 0.000
D74 Methaemoglobinaemia
0.657 0.342 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.657 0.342 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.657 0.342 0.000
I15 Secondary hypertension
0.656 0.344 0.000
I13 Hypertensive heart and renal disease
0.656 0.344 0.000
I11 Hypertensive heart disease
0.656 0.344 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.655 0.345 0.000
J04 Acute laryngitis and tracheitis
0.655 0.345 0.000
J01 Acute sinusitis
0.655 0.345 0.000
E14.8 With unspecified complications
0.655 0.345 0.000
E14.7 With multiple complications
0.655 0.345 0.000
E14.6 With other specified complications
0.655 0.345 0.000
E14.5 With peripheral circulatory complications
0.655 0.345 0.000
E14.4 With neurological complications
0.655 0.345 0.000
E14.2 Withrenal complications
0.655 0.345 0.000
E14.1 With ketoacidosis
0.655 0.345 0.000
E14.0 With coma
0.655 0.345 0.000
S81 Open wound of lower leg
0.655 0.345 0.000
I45 Other conduction disorders
0.654 0.345 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.654 0.345 0.000
S29 Other and unspecified injuries of thorax
0.654 0.346 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.654 0.346 0.000
S26 Injury of heart
0.654 0.346 0.000
S25 Injury of blood vessels of thorax
0.654 0.346 0.000
S24 Injury of nerves and spinal cord at thorax level
0.654 0.346 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.654 0.346 0.000
S21 Open wound of thorax
0.654 0.346 0.000
S20 Superficial injury of thorax
0.654 0.346 0.000
Z95.4 Presence of other heart-valve replacement
0.653 0.347 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.652 0.347 0.000
E34 Other endocrine disorders
0.652 0.347 0.000
E32 Diseases of thymus
0.652 0.347 0.000
E31 Polyglandular dysfunction
0.652 0.347 0.000
E30 Disorders of puberty, not elsewhere classified
0.652 0.347 0.000
E29 Testicular dysfunction
0.652 0.347 0.000
E26 Hyperaldosteronism
0.652 0.347 0.000
E25 Adrenogenital disorders
0.652 0.347 0.000
E24 Cushing's syndrome
0.652 0.347 0.000
E22 Hyperfunction of pituitary gland
0.652 0.347 0.000
E20 Hypoparathyroidism
0.652 0.347 0.000
Z80.5 Family history of malignant neoplasm of urinary tract
0.652 0.348 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.652 0.348 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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