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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs115260498
log Bayes Factor = 11.5409
Chromosome 4   position 92,258,655  (GRCh37) Explore rs115260498 on Ensembl!
Variant rs115260498 is part of Cluster X0072

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.999 0.001 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
Chapter XX External causes of morbidity and mortality
0.994 0.006 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.992 0.008 0.000
I74 Arterial embolism and thrombosis
0.992 0.008 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.990 0.010 0.000
S00-S09 Injuries to the head
0.990 0.010 0.000
S09 Other and unspecified injuries of head
0.984 0.016 0.000
S09.9 Unspecified injury of head
0.980 0.020 0.000
Chapter VII Diseases of the eye and adnexa
0.975 0.025 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.974 0.026 0.000
E00-E07 Disorders of thyroid gland
0.969 0.031 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.968 0.032 0.000
M20-M25 Other joint disorders
0.958 0.042 0.000
M50-M54 Other dorsopathies
0.957 0.043 0.000
E10-E14 Diabetes mellitus
0.951 0.049 0.000
W00-W19 Falls
0.945 0.055 0.000
H25-H28 Disorders of lens
0.943 0.057 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.943 0.057 0.000
Chapter V Mental and behavioural disorders
0.940 0.060 0.000
S70-S79 Injuries to the hip and thigh
0.936 0.064 0.000
H25 Senile cataract
0.935 0.065 0.000
I73 Other peripheral vascular diseases
0.931 0.069 0.000
M54 Dorsalgia
0.928 0.072 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.925 0.075 0.000
R69 Unknown and unspecified causes of morbidity
0.924 0.076 0.000
R50-R69 General symptoms and signs
0.923 0.077 0.000
M70-M79 Other soft tissue disorders
0.920 0.080 0.000
H43-H45 Disorders of vitreous body and globe
0.917 0.083 0.000
E05.9 Thyrotoxicosis, unspecified
0.915 0.085 0.000
H25.9 Senile cataract, unspecified
0.910 0.090 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.901 0.099 0.000
I77 Other disorders of arteries and arterioles
0.899 0.101 0.000
R51 Headache
0.898 0.102 0.000
M54.9 Dorsalgia, unspecified
0.897 0.103 0.000
H25.8 Other senile cataract
0.896 0.104 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.896 0.104 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.896 0.104 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.893 0.107 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.890 0.110 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.888 0.112 0.000
W19 Unspecified fall
0.887 0.113 0.000
S80-S89 Injuries to the knee and lower leg
0.880 0.120 0.000
I73.9 Peripheral vascular disease, unspecified
0.878 0.122 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.875 0.125 0.000
E20-E35 Disorders of other endocrine glands
0.872 0.128 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.872 0.128 0.000
M25 Other joint disorders, not elsewhere classified
0.871 0.129 0.000
M45-M49 Spondylopathies
0.870 0.130 0.000
E10 Insulin-dependent diabetes mellitus
0.870 0.130 0.000
M86-M90 Other osteopathies
0.869 0.131 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.861 0.139 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.860 0.140 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.858 0.142 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.857 0.143 0.000
M34 Systemic sclerosis
0.856 0.144 0.000
H55-H59 Other disorders of eye and adnexa
0.848 0.152 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.845 0.155 0.000
I78 Diseases of capillaries
0.844 0.156 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.844 0.156 0.000
I72 Other aneurysm
0.841 0.159 0.000
S10-S19 Injuries to the neck
0.840 0.160 0.000
S90-S99 Injuries to the ankle and foot
0.836 0.164 0.000
M24 Other specific joint derangements
0.836 0.164 0.000
W19.4 Street and highway
0.835 0.165 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.835 0.165 0.000
R73 Elevated blood glucose level
0.830 0.170 0.000
Chapter X Diseases of the respiratory system
0.829 0.171 0.000
S32 Fracture of lumbar spine and pelvis
0.829 0.171 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.827 0.173 0.000
M79.6 Pain in limb
0.826 0.174 0.000
T79-T79 Certain early complications of trauma
0.823 0.177 0.000
H43 Disorders of vitreous body
0.817 0.183 0.000
Y44 Agents primarily affecting blood constituents
0.816 0.184 0.000
Chapter I Certain infectious and parasitic diseases
0.814 0.186 0.000
R79 Other abnormal findings of blood chemistry
0.814 0.186 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.813 0.187 0.000
R60 Oedema, not elsewhere classified
0.813 0.187 0.000
M21 Other acquired deformities of limbs
0.812 0.188 0.000
S79 Other and unspecified injuries of hip and thigh
0.811 0.189 0.000
H44 Disorders of globe
0.810 0.190 0.000
Y52 Agents primarily affecting the cardiovascular system
0.809 0.191 0.000
Chapter XXII Codes for special purposes
0.807 0.193 0.000
I77.6 Arteritis, unspecified
0.803 0.197 0.000
M45 Ankylosing spondylitis
0.803 0.197 0.000
M22 Disorders of patella
0.801 0.199 0.000
W20-W49 Exposure to inanimate mechanical forces
0.800 0.200 0.000
S72 Fracture of femur
0.799 0.201 0.000
I70 Atherosclerosis
0.798 0.202 0.000
S05 Injury of eye and orbit
0.798 0.202 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.796 0.204 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.795 0.205 0.000
M54.1 Radiculopathy
0.794 0.206 0.000
Y42.5 Other oestrogens and progestogens
0.792 0.208 0.000
M79.66 Pain in limb (Lower leg)
0.790 0.210 0.000
J20-J22 Other acute lower respiratory infections
0.787 0.213 0.000
E04 Other non-toxic goitre
0.784 0.216 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.784 0.216 0.000
I74.8 Embolism and thrombosis of other arteries
0.783 0.217 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.782 0.218 0.000
H25.0 Senile incipient cataract
0.782 0.218 0.000
M05-M14 Inflammatory polyarthropathies
0.781 0.218 0.000
S20-S29 Injuries to the thorax
0.781 0.219 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.781 0.219 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.780 0.220 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.780 0.220 0.000
Y43 Primarily systemic agents
0.778 0.222 0.000
I20-I25 Ischaemic heart diseases
0.777 0.223 0.000
M35 Other systemic involvement of connective tissue
0.776 0.224 0.000
W08 Fall involving other furniture
0.776 0.224 0.000
F30-F39 Mood [affective] disorders
0.774 0.226 0.000
S50-S59 Injuries to the elbow and forearm
0.774 0.226 0.000
S81 Open wound of lower leg
0.774 0.226 0.000
M80-M85 Disorders of bone density and structure
0.772 0.228 0.000
E22 Hyperfunction of pituitary gland
0.772 0.228 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.771 0.229 0.000
E14 Unspecified diabetes mellitus
0.769 0.231 0.000
R73.9 Hyperglycaemia, unspecified
0.769 0.231 0.000
I95 Hypotension
0.767 0.233 0.000
S00 Superficial injury of head
0.767 0.233 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.765 0.235 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.764 0.236 0.000
E40-E46 Malnutrition
0.764 0.236 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.763 0.237 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.763 0.237 0.000
I21 Acute myocardial infarction
0.762 0.238 0.000
I26 Pulmonary embolism
0.761 0.239 0.000
E07 Other disorders of thyroid
0.761 0.239 0.000
Chapter VI Diseases of the nervous system
0.761 0.239 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.760 0.240 0.000
R64 Cachexia
0.758 0.242 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.757 0.243 0.000
J22 Unspecified acute lower respiratory infection
0.757 0.243 0.000
E10.3 With ophthalmic complications
0.756 0.244 0.000
E11 Non-insulin-dependent diabetes mellitus
0.754 0.246 0.000
H43.3 Other vitreous opacities
0.753 0.247 0.000
I74.5 Embolism and thrombosis of iliac artery
0.753 0.247 0.000
F80-F89 Disorders of psychological development
0.752 0.248 0.000
T43.2 Other and unspecified antidepressants
0.752 0.248 0.000
I99 Other and unspecified disorders of circulatory system
0.752 0.248 0.000
M71 Other bursopathies
0.751 0.249 0.000
S70 Superficial injury of hip and thigh
0.750 0.250 0.000
E13 Other specified diabetes mellitus
0.750 0.250 0.000
M91-M94 Chondropathies
0.749 0.251 0.000
I95.9 Hypotension, unspecified
0.748 0.252 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.747 0.253 0.000
E06 Thyroiditis
0.747 0.253 0.000
M24.1 Other articular cartilage disorders
0.747 0.253 0.000
H10-H13 Disorders of conjunctiva
0.746 0.254 0.000
I21.9 Acute myocardial infarction, unspecified
0.746 0.254 0.000
S06 Intracranial injury
0.746 0.254 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.746 0.254 0.000
T66-T78 Other and unspecified effects of external causes
0.745 0.255 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.744 0.255 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.743 0.257 0.000
M10 Gout
0.741 0.259 0.000
M00-M03 Infectious arthropathies
0.741 0.259 0.000
M79.7 Fibromyalgia
0.740 0.260 0.000
M25.5 Pain in joint
0.740 0.260 0.000
M40-M43 Deforming dorsopathies
0.738 0.262 0.000
I78.0 Hereditary haemorrhagic telangiectasia
0.734 0.266 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.734 0.266 0.000
S72.1 Pertrochanteric fracture
0.734 0.266 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.733 0.267 0.000
E10.1 With ketoacidosis
0.730 0.270 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.729 0.271 0.000
Chapter II Neoplasms
0.728 0.272 0.000
M60-M63 Disorders of muscles
0.728 0.272 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.727 0.273 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.726 0.274 0.000
F20 Schizophrenia
0.726 0.274 0.000
M34.8 Other forms of systemic sclerosis
0.725 0.275 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.724 0.276 0.000
X60-X84 Intentional self-harm
0.723 0.277 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.723 0.277 0.000
X20-X29 Contact with venomous animals and plants
0.723 0.277 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.722 0.278 0.000
S79.9 Unspecified injury of hip and thigh
0.721 0.279 0.000
M34.9 Systemic sclerosis, unspecified
0.721 0.279 0.000
F29 Unspecified nonorganic psychosis
0.720 0.280 0.000
S19 Other and unspecified injuries of neck
0.720 0.280 0.000
X50-X57 Overexertion, travel and privation
0.718 0.282 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
H44.2 Degenerative myopia
0.716 0.283 0.000
I10-I15 Hypertensive diseases
0.716 0.284 0.000
I60-I69 Cerebrovascular diseases
0.716 0.284 0.000
M89 Other disorders of bone
0.715 0.285 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.715 0.285 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.715 0.285 0.000
M79.8 Other specified soft tissue disorders
0.714 0.286 0.000
F60-F69 Disorders of adult personality and behaviour
0.714 0.286 0.000
Y35-Y36 Legal intervention and operations of war
0.713 0.287 0.000
Y10-Y34 Event of undetermined intent
0.713 0.287 0.000
Y00-Y09 Assault
0.713 0.287 0.000
X85-X99 Assault
0.713 0.287 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.713 0.287 0.000
X30-X39 Exposure to forces of nature
0.713 0.287 0.000
X10-X19 Contact with heat and hot substances
0.713 0.287 0.000
X00-X09 Exposure to smoke, fire and flames
0.713 0.287 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.713 0.287 0.000
W75-W84 Other accidental threats to breathing
0.713 0.287 0.000
W65-W74 Accidental drowning and submersion
0.713 0.287 0.000
W50-W64 Exposure to animate mechanical forces
0.713 0.287 0.000
V98-V99 Other and unspecified transport accidents
0.713 0.287 0.000
V95-V97 Air and space transport accidents
0.713 0.287 0.000
V90-V94 Water transport accidents
0.713 0.287 0.000
V70-V79 Bus occupant injured in transport accident
0.713 0.287 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.713 0.287 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.713 0.287 0.000
V40-V49 Car occupant injured in transport accident
0.713 0.287 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.713 0.287 0.000
V01-V09 Pedestrian injured in transport accident
0.713 0.287 0.000
H27 Other disorders of lens
0.713 0.287 0.000
M10.9 Gout, unspecified
0.713 0.287 0.000
W19.9 Unspecified place
0.712 0.288 0.000
S91 Open wound of ankle and foot
0.711 0.289 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.711 0.289 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.711 0.289 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.711 0.289 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.710 0.290 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.710 0.290 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.710 0.290 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.710 0.290 0.000
T36 Poisoning by systemic antibiotics
0.710 0.290 0.000
S08 Traumatic amputation of part of head
0.710 0.290 0.000
S07 Crushing injury of head
0.710 0.290 0.000
S04 Injury of cranial nerves
0.710 0.290 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.710 0.290 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.709 0.291 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.709 0.291 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.708 0.292 0.000
Y44.2 Anticoagulants
0.707 0.293 0.000
T39.1 4-Aminophenol derivatives
0.706 0.294 0.000
M25.7 Osteophyte
0.706 0.294 0.000
S09.8 Other specified injuries of head
0.706 0.294 0.000
S09.7 Multiple injuries of head
0.706 0.294 0.000
S09.2 Traumatic rupture of ear drum
0.706 0.294 0.000
S09.1 Injury of muscle and tendon of head
0.706 0.294 0.000
S09.0 Injury of blood vessels of head, not elsewhere classified
0.706 0.294 0.000
M54.6 Pain in thoracic spine
0.705 0.295 0.000
E27 Other disorders of adrenal gland
0.704 0.296 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.703 0.297 0.000
V80-V89 Other land transport accidents
0.703 0.297 0.000
T39.0 Salicylates
0.703 0.297 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.702 0.298 0.000
S40-S49 Injuries to the shoulder and upper arm
0.702 0.298 0.000
S32.5 Fracture of pubis
0.701 0.299 0.000
B95-B98 Bacterial, viral and other infectious agents
0.701 0.299 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.701 0.299 0.000
W07 Fall involving chair
0.699 0.301 0.000
M79.9 Soft tissue disorder, unspecified
0.699 0.301 0.000
R60.0 Localised oedema
0.699 0.301 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.696 0.304 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.696 0.304 0.000
R60.1 Generalised oedema
0.695 0.305 0.000
M10.99 Gout, unspecified (Site unspecified)
0.695 0.305 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.695 0.305 0.000
E00 Congenital iodine-deficiency syndrome
0.695 0.305 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.695 0.305 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.695 0.305 0.000
Y59 Other and unspecified vaccines and biological substances
0.694 0.306 0.000
Y58 Bacterial vaccines
0.694 0.306 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.694 0.306 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.694 0.306 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.694 0.306 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.694 0.306 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.694 0.306 0.000
Y48 Anaesthetics and therapeutic gases
0.694 0.306 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.694 0.306 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.694 0.306 0.000
I77.1 Stricture of artery
0.694 0.306 0.000
M65-M68 Disorders of synovium and tendon
0.693 0.307 0.000
Y40 Systemic antibiotics
0.690 0.309 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.690 0.310 0.000
M79.1 Myalgia
0.690 0.310 0.000
E10.4 With neurological complications
0.690 0.310 0.000
Y83.6 Removal of other organ (partial) (total)
0.690 0.310 0.000
M53 Other dorsopathies, not elsewhere classified
0.689 0.311 0.000
M51 Other intervertebral disk disorders
0.689 0.311 0.000
G20-G26 Extrapyramidal and movement disorders
0.688 0.311 0.000
S36 Injury of intra-abdominal organs
0.688 0.312 0.000
S72.10 Pertrochanteric fracture (closed)
0.687 0.313 0.000
S32.0 Fracture of lumbar vertebra
0.687 0.313 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.687 0.313 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.687 0.313 0.000
M33 Dermatopolymyositis
0.687 0.313 0.000
M32 Systemic lupus erythematosus
0.687 0.313 0.000
M30 Polyarteritis nodosa and related conditions
0.687 0.313 0.000
I73.0 Raynaud's syndrome
0.686 0.314 0.000
J90-J94 Other diseases of pleura
0.685 0.315 0.000
M54.3 Sciatica
0.685 0.315 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.684 0.316 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.683 0.317 0.000
M35.0 Sicca syndrome [Sjogren]
0.683 0.317 0.000
E34 Other endocrine disorders
0.682 0.318 0.000
E12 Malnutrition-related diabetes mellitus
0.682 0.318 0.000
M54.2 Cervicalgia
0.681 0.319 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.681 0.319 0.000
M25.8 Other specified joint disorders
0.679 0.321 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.678 0.322 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.678 0.322 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.678 0.322 0.000
W18 Other fall on same level
0.678 0.322 0.000
W17 Other fall from one level to another
0.678 0.322 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.678 0.322 0.000
W15 Fall from cliff
0.678 0.322 0.000
W14 Fall from tree
0.678 0.322 0.000
W12 Fall on and from scaffolding
0.678 0.322 0.000
W11 Fall on and from ladder
0.678 0.322 0.000
W10 Fall on and from stairs and steps
0.678 0.322 0.000
W09 Fall involving playground equipment
0.678 0.322 0.000
W05 Fall involving wheelchair
0.678 0.322 0.000
W04 Fall while being carried or supported by other persons
0.678 0.322 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.678 0.322 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.678 0.322 0.000
W00 Fall on same level involving ice and snow
0.678 0.322 0.000
F17.1 Harmful use
0.678 0.322 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.677 0.323 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.676 0.324 0.000
E05.8 Other thyrotoxicosis
0.676 0.324 0.000
E05.5 Thyroid crisis or storm
0.676 0.324 0.000
E05.4 Thyrotoxicosis factitia
0.676 0.324 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.676 0.324 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.676 0.324 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.676 0.324 0.000
R57 Shock, not elsewhere classified
0.676 0.324 0.000
F31 Bipolar affective disorder
0.676 0.324 0.000
H55 Nystagmus and other irregular eye movements
0.675 0.325 0.000
M87 Osteonecrosis
0.675 0.325 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.674 0.325 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.674 0.326 0.000
F70-F79 Mental retardation
0.674 0.326 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.673 0.326 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.673 0.327 0.000
V20-V29 Motorcycle rider injured in transport accident
0.673 0.327 0.000
E10.5 With peripheral circulatory complications
0.673 0.327 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.673 0.327 0.000
S82 Fracture of lower leg, including ankle
0.672 0.328 0.000
I71 Aortic aneurysm and dissection
0.672 0.328 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.672 0.328 0.000
R73.0 Abnormal glucose tolerance test
0.671 0.329 0.000
S78 Traumatic amputation of hip and thigh
0.671 0.329 0.000
S77 Crushing injury of hip and thigh
0.671 0.329 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.671 0.329 0.000
S75 Injury of blood vessels at hip and thigh level
0.671 0.329 0.000
S74 Injury of nerves at hip and thigh level
0.671 0.329 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.671 0.329 0.000
S71 Open wound of hip and thigh
0.671 0.329 0.000
E11.5 With peripheral circulatory complications
0.671 0.329 0.000
H25.2 Senile cataract, morgagnian type
0.670 0.330 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.670 0.330 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.670 0.330 0.000
H20 Iridocyclitis
0.669 0.330 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.668 0.332 0.000
I73.8 Other specified peripheral vascular diseases
0.667 0.332 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.667 0.332 0.000
H21 Other disorders of iris and ciliary body
0.668 0.332 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.668 0.332 0.000
I72.0 Aneurysm of carotid artery
0.667 0.333 0.000
J95-J99 Other diseases of the respiratory system
0.667 0.333 0.000
E10.2 With renal complications
0.667 0.333 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.666 0.334 0.000
M22.4 Chondromalacia patellae
0.666 0.334 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.666 0.334 0.000
M54.8 Other dorsalgia
0.666 0.334 0.000
M54.0 Panniculitis affecting regions of neck and back
0.666 0.334 0.000
E29 Testicular dysfunction
0.666 0.334 0.000
S05.8 Other injuries of eye and orbit
0.665 0.334 0.000
M21.2 Flexion deformity
0.665 0.335 0.000
S80 Superficial injury of lower leg
0.664 0.336 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.664 0.336 0.000
S56 Injury of muscle and tendon at forearm level
0.664 0.336 0.000
S32.7 Multiple fractures of lumbar spine and pelvis
0.663 0.337 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.663 0.337 0.000
M50 Cervical disk disorders
0.663 0.337 0.000
C64-C68 Malignant neoplasms of urinary tract
0.663 0.337 0.000
R41.3 Other amnesia
0.662 0.338 0.000
M54.16 Radiculopathy (Lumbar region)
0.662 0.338 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.662 0.338 0.000
R62 Lack of expected normal physiological development
0.662 0.338 0.000
R58 Haemorrhage, not elsewhere classified
0.662 0.338 0.000
F22 Persistent delusional disorders
0.662 0.338 0.000
M76 Enthesopathies of lower limb, excluding foot
0.660 0.340 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.660 0.340 0.000
M79.0 Rheumatism, unspecified
0.659 0.341 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.659 0.341 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.659 0.341 0.000
W06 Fall involving bed
0.658 0.342 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.658 0.342 0.000
I12 Hypertensive renal disease
0.657 0.343 0.000
I72.4 Aneurysm of artery of lower extremity
0.656 0.344 0.000
M54.4 Lumbago with sciatica
0.656 0.344 0.000
R68 Other general symptoms and signs
0.656 0.344 0.000
M86 Osteomyelitis
0.656 0.344 0.000
S00.3 Superficial injury of nose
0.656 0.344 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.655 0.345 0.000
M79.5 Residual foreign body in soft tissue
0.655 0.345 0.000
W08.0 Home
0.655 0.345 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.654 0.346 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.653 0.347 0.000
M21.6 Other acquired deformities of ankle and foot
0.652 0.347 0.000
V10-V19 Pedal cyclist injured in transport accident
0.652 0.348 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.652 0.348 0.000
M25.4 Effusion of joint
0.651 0.349 0.000
G90-G99 Other disorders of the nervous system
0.651 0.349 0.000
W13 Fall from, out of or through building or structure
0.650 0.350 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.650 0.350 0.000
Q60-Q64 Congenital malformations of the urinary system
0.650 0.350 0.000
M85 Other disorders of bone density and structure
0.650 0.350 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.649 0.351 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.649 0.351 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.648 0.352 0.000
T42.4 Benzodiazepines
0.648 0.352 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.647 0.353 0.000
R40 Somnolence, stupor and coma
0.647 0.353 0.000
M88 Paget's disease of bone [osteitis deformans]
0.646 0.354 0.000
D10-D36 Benign neoplasms
0.646 0.354 0.000
T43.9 Psychotropic drug, unspecified
0.646 0.354 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.646 0.354 0.000
T43.6 Psychostimulants with abuse potential
0.646 0.354 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.646 0.354 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.646 0.354 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.645 0.355 0.000
I77.5 Necrosis of artery
0.645 0.355 0.000
I77.4 Coeliac artery compression syndrome
0.645 0.355 0.000
I77.3 Arterial fibromuscular dysplasia
0.645 0.355 0.000
I77.2 Rupture of artery
0.645 0.355 0.000
I77.0 Arteriovenous fistula, acquired
0.645 0.355 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.643 0.357 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.643 0.357 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.643 0.357 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.643 0.357 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.643 0.357 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.643 0.357 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.643 0.357 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.642 0.357 0.000
M79.3 Panniculitis, unspecified
0.642 0.357 0.000
M79.2 Neuralgia and neuritis, unspecified
0.642 0.357 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.642 0.357 0.000
S37 Injury of urinary and pelvic organs
0.642 0.357 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.642 0.357 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.642 0.357 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.642 0.357 0.000
S31 Open wound of abdomen, lower back and pelvis
0.642 0.357 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.642 0.358 0.000
M79.67 Pain in limb (Ankle and foot)
0.642 0.358 0.000
H57 Other disorders of eye and adnexa
0.641 0.359 0.000
I72.8 Aneurysm of other specified arteries
0.640 0.360 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.640 0.360 0.000
E14.9 Without complications
0.639 0.361 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.638 0.361 0.000
S81.0 Open wound of knee
0.638 0.362 0.000
W49 Exposure to other and unspecified inanimate mechanical forces
0.638 0.362 0.000
Y42.9 Other and unspecified hormone antagonists
0.638 0.362 0.000
Y42.4 Oral contraceptives
0.638 0.362 0.000
Y42.2 Antithyroid drugs
0.638 0.362 0.000
Y42.1 Thyroid hormones and substitutes
0.638 0.362 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.638 0.362 0.000
M79.61 Pain in limb (Shoulder region)
0.637 0.363 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.637 0.363 0.000
R77 Other abnormalities of plasma proteins
0.637 0.363 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.637 0.363 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.637 0.363 0.000
R71 Abnormality of red blood cells
0.637 0.363 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.637 0.363 0.000
W19.8 Other specified place
0.636 0.364 0.000
W19.5 Trade and service area
0.636 0.364 0.000
W19.0 Home
0.636 0.364 0.000
W19.7 Farm
0.636 0.364 0.000
W19.6 Industrial and construction area
0.636 0.364 0.000
W19.1 Residential institution
0.636 0.364 0.000
I77.8 Other specified disorders of arteries and arterioles
0.636 0.364 0.000
S27 Injury of other and unspecified intrathoracic organs
0.635 0.364 0.000
S19.9 Unspecified injury of neck
0.634 0.366 0.000
W19.3 Sports and athletics area
0.634 0.366 0.000
E04.9 Non-toxic goitre, unspecified
0.633 0.367 0.000
Q80-Q89 Other congenital malformations
0.633 0.367 0.000
S99 Other and unspecified injuries of ankle and foot
0.632 0.368 0.000
F20.9 Schizophrenia, unspecified
0.632 0.368 0.000
S88 Traumatic amputation of lower leg
0.631 0.369 0.000
S87 Crushing injury of lower leg
0.631 0.369 0.000
S86 Injury of muscle and tendon at lower leg level
0.631 0.369 0.000
S85 Injury of blood vessels at lower leg level
0.631 0.369 0.000
S84 Injury of nerves at lower leg level
0.631 0.369 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.631 0.369 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.630 0.370 0.000
M21.3 Wrist or foot drop (acquired)
0.630 0.370 0.000
E16 Other disorders of pancreatic internal secretion
0.630 0.370 0.000
T17 Foreign body in respiratory tract
0.629 0.371 0.000
M90 Osteopathies in diseases classified elsewhere
0.629 0.371 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.629 0.371 0.000
Chapter XI Diseases of the digestive system
0.628 0.372 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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