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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs115310313
log Bayes Factor = 22.9207
Chromosome 3   position 51,811,751  (GRCh37) Explore rs115310313 on Ensembl!
Variant rs115310313 is part of Cluster X0047

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
J40-J47 Chronic lower respiratory diseases
0.999 0.001 0.000
Chapter XXI Factors influencing health status and contact with health services
0.998 0.002 0.000
J44 Other chronic obstructive pulmonary disease
0.997 0.003 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.996 0.004 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.995 0.005 0.000
I50 Heart failure
0.993 0.007 0.000
L03 Cellulitis
0.992 0.008 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.992 0.008 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.992 0.008 0.000
L03.1 Cellulitis of other parts of limb
0.990 0.010 0.000
Chapter XIV Diseases of the genitourinary system
0.988 0.012 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.987 0.013 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.986 0.014 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.983 0.017 0.000
Chapter XX External causes of morbidity and mortality
0.980 0.020 0.000
S00-S09 Injuries to the head
0.979 0.021 0.000
E70-E90 Metabolic disorders
0.977 0.023 0.000
I50.0 Congestive heart failure
0.976 0.024 0.000
Z45 Adjustment and management of implanted device
0.973 0.027 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.972 0.028 0.000
S60-S69 Injuries to the wrist and hand
0.969 0.031 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.965 0.035 0.000
Chapter V Mental and behavioural disorders
0.962 0.038 0.000
E86 Volume depletion
0.961 0.039 0.000
N30-N39 Other diseases of urinary system
0.960 0.040 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.958 0.042 0.000
J90-J94 Other diseases of pleura
0.958 0.042 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.958 0.042 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.957 0.043 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.956 0.044 0.000
S01 Open wound of head
0.955 0.045 0.000
Chapter VIII Diseases of the ear and mastoid process
0.955 0.045 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.951 0.049 0.000
I45 Other conduction disorders
0.951 0.049 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.948 0.052 0.000
Z60 Problems related to social environment
0.946 0.054 0.000
M20-M25 Other joint disorders
0.939 0.061 0.000
R79 Other abnormal findings of blood chemistry
0.938 0.062 0.000
W00-W19 Falls
0.930 0.070 0.000
Z46 Fitting and adjustment of other devices
0.928 0.072 0.000
Z60.2 Living alone
0.926 0.074 0.000
Z45.2 Adjustment and management of vascular access device
0.926 0.074 0.000
I50.1 Left ventricular failure
0.922 0.078 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.918 0.082 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.917 0.083 0.000
I83 Varicose veins of lower extremities
0.916 0.084 0.000
I45.1 Other and unspecified right bundle-branch block
0.916 0.084 0.000
N39 Other disorders of urinary system
0.915 0.085 0.000
I05-I09 Chronic rheumatic heart diseases
0.914 0.086 0.000
M80-M85 Disorders of bone density and structure
0.914 0.086 0.000
N17-N19 Renal failure
0.914 0.086 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.913 0.087 0.000
J90 Pleural effusion, not elsewhere classified
0.909 0.091 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.908 0.092 0.000
S62 Fracture at wrist and hand level
0.907 0.093 0.000
I35 Nonrheumatic aortic valve disorders
0.905 0.095 0.000
S00 Superficial injury of head
0.902 0.098 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.895 0.105 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.892 0.108 0.000
S80-S89 Injuries to the knee and lower leg
0.892 0.108 0.000
Chapter I Certain infectious and parasitic diseases
0.889 0.111 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.888 0.111 0.000
N18 Chronic renal failure
0.886 0.114 0.000
I49 Other cardiac arrhythmias
0.884 0.116 0.000
Z46.6 Fitting and adjustment of urinary device
0.883 0.117 0.000
I71 Aortic aneurysm and dissection
0.883 0.117 0.000
N10-N16 Renal tubulo-interstitial diseases
0.881 0.119 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.878 0.122 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.878 0.122 0.000
W19 Unspecified fall
0.876 0.124 0.000
S01.9 Open wound of head, part unspecified
0.876 0.124 0.000
I51 Complications and ill-defined descriptions of heart disease
0.875 0.125 0.000
N39.0 Urinary tract infection, site not specified
0.872 0.128 0.000
I80 Phlebitis and thrombophlebitis
0.871 0.129 0.000
N32 Other disorders of bladder
0.871 0.129 0.000
N25-N29 Other disorders of kidney and ureter
0.865 0.135 0.000
Z45.8 Adjustment and management of other implanted devices
0.864 0.136 0.000
J30-J39 Other diseases of upper respiratory tract
0.862 0.138 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.861 0.139 0.000
S01.0 Open wound of scalp
0.859 0.141 0.000
S50-S59 Injuries to the elbow and forearm
0.857 0.143 0.000
H60-H62 Diseases of external ear
0.857 0.143 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.856 0.144 0.000
S90-S99 Injuries to the ankle and foot
0.856 0.144 0.000
I33 Acute and subacute endocarditis
0.855 0.145 0.000
M81 Osteoporosis without pathological fracture
0.853 0.147 0.000
I42 Cardiomyopathy
0.853 0.147 0.000
Z47 Other orthopaedic follow-up care
0.851 0.149 0.000
R47-R49 Symptoms and signs involving speech and voice
0.848 0.152 0.000
S00.9 Superficial injury of head, part unspecified
0.844 0.156 0.000
J09-J18 Influenza and pneumonia
0.839 0.161 0.000
E65-E68 Obesity and other hyperalimentation
0.838 0.162 0.000
Z43 Attention to artificial openings
0.837 0.163 0.000
J40 Bronchitis, not specified as acute or chronic
0.835 0.165 0.000
H65-H75 Diseases of middle ear and mastoid
0.834 0.166 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.833 0.167 0.000
D60-D64 Aplastic and other anaemias
0.831 0.169 0.000
I08 Multiple valve diseases
0.830 0.170 0.000
E00-E07 Disorders of thyroid gland
0.829 0.170 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.829 0.171 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.826 0.174 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.825 0.175 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.824 0.176 0.000
S70-S79 Injuries to the hip and thigh
0.823 0.176 0.000
N99-N99 Other disorders of the genitourinary system
0.822 0.178 0.000
J60-J70 Lung diseases due to external agents
0.820 0.180 0.000
N35 Urethral stricture
0.820 0.180 0.000
I31 Other diseases of pericardium
0.818 0.182 0.000
D69 Purpura and other haemorrhagic conditions
0.817 0.183 0.000
S62.6 Fracture of other finger
0.814 0.186 0.000
Z22 Carrier of infectious disease
0.813 0.187 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.811 0.189 0.000
E50-E64 Other nutritional deficiencies
0.809 0.190 0.000
M21 Other acquired deformities of limbs
0.809 0.191 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.809 0.191 0.000
N39.4 Other specified urinary incontinence
0.808 0.192 0.000
I51.7 Cardiomegaly
0.808 0.192 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.807 0.193 0.000
I38 Endocarditis, valve unspecified
0.807 0.193 0.000
M24 Other specific joint derangements
0.807 0.193 0.000
J47 Bronchiectasis
0.805 0.195 0.000
M81.9 Osteoporosis, unspecified
0.804 0.196 0.000
H80-H83 Diseases of inner ear
0.804 0.196 0.000
J92 Pleural plaque
0.804 0.196 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.803 0.197 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.802 0.198 0.000
N18.3 Chronic kidney disease, stage 3
0.802 0.198 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.801 0.199 0.000
R71 Abnormality of red blood cells
0.797 0.203 0.000
L08 Other local infections of skin and subcutaneous tissue
0.796 0.204 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.796 0.204 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.795 0.205 0.000
I78 Diseases of capillaries
0.792 0.208 0.000
J45 Asthma
0.791 0.209 0.000
I82 Other venous embolism and thrombosis
0.791 0.209 0.000
S69 Other and unspecified injuries of wrist and hand
0.790 0.210 0.000
S82 Fracture of lower leg, including ankle
0.789 0.211 0.000
I77 Other disorders of arteries and arterioles
0.789 0.211 0.000
E83 Disorders of mineral metabolism
0.786 0.214 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.786 0.214 0.000
I46 Cardiac arrest
0.786 0.214 0.000
I47 Paroxysmal tachycardia
0.781 0.219 0.000
I86 Varicose veins of other sites
0.780 0.220 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.778 0.222 0.000
R50-R69 General symptoms and signs
0.778 0.222 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.777 0.222 0.000
S20-S29 Injuries to the thorax
0.777 0.223 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.777 0.223 0.000
Z63 Other problems related to primary support group, including family circumstances
0.777 0.223 0.000
L40-L45 Papulosquamous disorders
0.777 0.223 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.777 0.223 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.777 0.223 0.000
W50-W64 Exposure to animate mechanical forces
0.777 0.223 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.777 0.223 0.000
W19.9 Unspecified place
0.777 0.223 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.774 0.226 0.000
T66-T78 Other and unspecified effects of external causes
0.772 0.227 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.771 0.228 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.770 0.229 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.770 0.230 0.000
L03.2 Cellulitis of face
0.770 0.230 0.000
D50-D53 Nutritional anaemias
0.768 0.232 0.000
M31 Other necrotising vasculopathies
0.768 0.232 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.768 0.232 0.000
N32.3 Diverticulum of bladder
0.768 0.232 0.000
V10-V19 Pedal cyclist injured in transport accident
0.767 0.233 0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device
0.765 0.235 0.000
J95-J99 Other diseases of the respiratory system
0.764 0.236 0.000
I49.8 Other specified cardiac arrhythmias
0.764 0.236 0.000
S67 Crushing injury of wrist and hand
0.763 0.237 0.000
T86 Failure and rejection of transplanted organs and tissues
0.762 0.238 0.000
R79.0 Abnormal level of blood mineral
0.762 0.238 0.000
M23 Internal derangement of knee
0.762 0.238 0.000
S01.8 Open wound of other parts of head
0.762 0.238 0.000
M25 Other joint disorders, not elsewhere classified
0.762 0.238 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.761 0.239 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.759 0.241 0.000
F17.2 Dependence syndrome
0.758 0.242 0.000
W20-W49 Exposure to inanimate mechanical forces
0.758 0.242 0.000
Z41 Procedures for purposes other than remedying health state
0.757 0.243 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.757 0.243 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.755 0.245 0.000
J32 Chronic sinusitis
0.754 0.246 0.000
I33.0 Acute and subacute infective endocarditis
0.752 0.248 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.751 0.249 0.000
E87.7 Fluid overload
0.751 0.249 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.750 0.250 0.000
F60-F69 Disorders of adult personality and behaviour
0.749 0.251 0.000
Z22.3 Carrier of other specified bacterial diseases
0.749 0.251 0.000
R79.9 Abnormal finding of blood chemistry, unspecified
0.749 0.251 0.000
F10.0 Acute intoxication
0.749 0.251 0.000
X60-X84 Intentional self-harm
0.749 0.251 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.747 0.253 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.747 0.253 0.000
Z50 Care involving use of rehabilitation procedures
0.746 0.254 0.000
E20-E35 Disorders of other endocrine glands
0.745 0.255 0.000
N18.5 Chronic kidney disease, stage 5
0.745 0.255 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.744 0.256 0.000
W19.4 Street and highway
0.744 0.256 0.000
E88 Other metabolic disorders
0.741 0.259 0.000
Y52 Agents primarily affecting the cardiovascular system
0.740 0.260 0.000
D69.6 Thrombocytopenia, unspecified
0.740 0.260 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.739 0.261 0.000
H72 Perforation of tympanic membrane
0.739 0.261 0.000
L20-L30 Dermatitis and eczema
0.739 0.261 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.739 0.261 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.739 0.261 0.000
M65-M68 Disorders of synovium and tendon
0.738 0.262 0.000
J34 Other disorders of nose and nasal sinuses
0.737 0.263 0.000
L03.3 Cellulitis of trunk
0.736 0.264 0.000
H61 Other disorders of external ear
0.736 0.264 0.000
M86-M90 Other osteopathies
0.735 0.265 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.735 0.265 0.000
S01.3 Open wound of ear
0.735 0.265 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.734 0.266 0.000
S61 Open wound of wrist and hand
0.732 0.268 0.000
I30 Acute pericarditis
0.732 0.268 0.000
Z43.2 Attention to ileostomy
0.731 0.269 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.730 0.270 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.729 0.271 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.727 0.273 0.000
E66 Obesity
0.727 0.273 0.000
I05 Rheumatic mitral valve diseases
0.727 0.273 0.000
I42.0 Dilated cardiomyopathy
0.726 0.274 0.000
Z45.1 Adjustment and management of infusion pump
0.725 0.275 0.000
T82.1 Mechanical complication of cardiac electronic device
0.723 0.276 0.000
R60 Oedema, not elsewhere classified
0.723 0.277 0.000
N18.9 Chronic renal failure, unspecified
0.723 0.277 0.000
A30-A49 Other bacterial diseases
0.723 0.277 0.000
M40-M43 Deforming dorsopathies
0.723 0.277 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.722 0.278 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.722 0.278 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.721 0.279 0.000
Y44 Agents primarily affecting blood constituents
0.721 0.279 0.000
N39.3 Stress incontinence
0.720 0.280 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.720 0.280 0.000
I84 Haemorrhoids
0.720 0.280 0.000
S40-S49 Injuries to the shoulder and upper arm
0.719 0.280 0.000
N35.9 Urethral stricture, unspecified
0.719 0.281 0.000
M20 Acquired deformities of fingers and toes
0.719 0.281 0.000
S62.60 Fracture of other finger (closed)
0.718 0.282 0.000
I70 Atherosclerosis
0.717 0.282 0.000
J30 Vasomotor and allergic rhinitis
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I27 Other pulmonary heart diseases
0.717 0.283 0.000
I35.0 Aortic (valve) stenosis
0.717 0.283 0.000
R49 Voice disturbances
0.716 0.283 0.000
J41 Simple and mucopurulent chronic bronchitis
0.716 0.284 0.000
S52 Fracture of forearm
0.716 0.284 0.000
H60 Otitis externa
0.715 0.285 0.000
D68 Other coagulation defects
0.715 0.285 0.000
L10-L14 Bullous disorders
0.714 0.285 0.000
L04 Acute lymphadenitis
0.713 0.287 0.000
L01 Impetigo
0.713 0.287 0.000
L00 Staphylococcal scalded skin syndrome
0.713 0.287 0.000
Z57 Occupational exposure to risk-factors
0.713 0.287 0.000
I47.2 Ventricular tachycardia
0.712 0.287 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.712 0.288 0.000
M91-M94 Chondropathies
0.712 0.288 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.712 0.288 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.712 0.288 0.000
S62.5 Fracture of thumb
0.711 0.288 0.000
L03.8 Cellulitis of other sites
0.711 0.289 0.000
E40-E46 Malnutrition
0.711 0.289 0.000
Z54 Convalescence
0.711 0.289 0.000
Z52 Donors of organs and tissues
0.711 0.289 0.000
Z44 Fitting and adjustment of external prosthetic device
0.711 0.289 0.000
I49.3 Ventricular premature depolarisation
0.711 0.289 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.710 0.290 0.000
I35.1 Aortic (valve) insufficiency
0.710 0.290 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.710 0.290 0.000
S64 Injury of nerves at wrist and hand level
0.710 0.290 0.000
M82 Osteoporosis in diseases classified elsewhere
0.709 0.291 0.000
I89.0 Lymphoedema, not elsewhere classified
0.709 0.291 0.000
I72 Other aneurysm
0.709 0.291 0.000
V20-V29 Motorcycle rider injured in transport accident
0.708 0.291 0.000
T87 Complications peculiar to reattachment and amputation
0.707 0.293 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.707 0.293 0.000
E03 Other hypothyroidism
0.707 0.293 0.000
I88 Nonspecific lymphadenitis
0.707 0.293 0.000
I87 Other disorders of veins
0.707 0.293 0.000
I81 Portal vein thrombosis
0.707 0.293 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.707 0.293 0.000
Chapter XXII Codes for special purposes
0.707 0.293 0.000
Z49 Care involving dialysis
0.707 0.293 0.000
I49.1 Atrial premature depolarisation
0.705 0.295 0.000
R47 Speech disturbances, not elsewhere classified
0.705 0.295 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.704 0.296 0.000
M84 Disorders of continuity of bone
0.704 0.296 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.704 0.296 0.000
F10.4 Withdrawal state with delirium
0.704 0.296 0.000
N28.8 Other specified disorders of kidney and ureter
0.704 0.296 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.704 0.296 0.000
M23.3 Other meniscus derangements
0.704 0.296 0.000
J42 Unspecified chronic bronchitis
0.703 0.297 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.703 0.297 0.000
Y35-Y36 Legal intervention and operations of war
0.703 0.297 0.000
Y10-Y34 Event of undetermined intent
0.703 0.297 0.000
Y00-Y09 Assault
0.703 0.297 0.000
X85-X99 Assault
0.703 0.297 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.703 0.297 0.000
X50-X57 Overexertion, travel and privation
0.703 0.297 0.000
X30-X39 Exposure to forces of nature
0.703 0.297 0.000
X20-X29 Contact with venomous animals and plants
0.703 0.297 0.000
X10-X19 Contact with heat and hot substances
0.703 0.297 0.000
X00-X09 Exposure to smoke, fire and flames
0.703 0.297 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.703 0.297 0.000
W75-W84 Other accidental threats to breathing
0.703 0.297 0.000
W65-W74 Accidental drowning and submersion
0.703 0.297 0.000
V98-V99 Other and unspecified transport accidents
0.703 0.297 0.000
V95-V97 Air and space transport accidents
0.703 0.297 0.000
V90-V94 Water transport accidents
0.703 0.297 0.000
V80-V89 Other land transport accidents
0.703 0.297 0.000
V70-V79 Bus occupant injured in transport accident
0.703 0.297 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.703 0.297 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.703 0.297 0.000
V40-V49 Car occupant injured in transport accident
0.703 0.297 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.703 0.297 0.000
V01-V09 Pedestrian injured in transport accident
0.703 0.297 0.000
S90 Superficial injury of ankle and foot
0.703 0.297 0.000
S08 Traumatic amputation of part of head
0.702 0.298 0.000
S07 Crushing injury of head
0.702 0.298 0.000
S05 Injury of eye and orbit
0.702 0.298 0.000
S04 Injury of cranial nerves
0.702 0.298 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.702 0.298 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.702 0.298 0.000
S01.2 Open wound of nose
0.702 0.298 0.000
S62.3 Fracture of other metacarpal bone
0.701 0.298 0.000
E85 Amyloidosis
0.701 0.299 0.000
E84 Cystic fibrosis
0.701 0.299 0.000
E79 Disorders of purine and pyrimidine metabolism
0.701 0.299 0.000
E77 Disorders of glycoprotein metabolism
0.701 0.299 0.000
E76 Disorders of glycosaminoglycan metabolism
0.701 0.299 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.701 0.299 0.000
E74 Other disorders of carbohydrate metabolism
0.701 0.299 0.000
E73 Lactose intolerance
0.701 0.299 0.000
E72 Other disorders of amino-acid metabolism
0.701 0.299 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.701 0.299 0.000
E70 Disorders of aromatic amino-acid metabolism
0.701 0.299 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.701 0.299 0.000
W07 Fall involving chair
0.700 0.299 0.000
S01.1 Open wound of eyelid and periocular area
0.699 0.301 0.000
M22 Disorders of patella
0.698 0.302 0.000
J46 Status asthmaticus
0.698 0.302 0.000
Z45.9 Adjustment and management of unspecified implanted device
0.698 0.302 0.000
Z45.3 Adjustment and management of implanted hearing device
0.698 0.302 0.000
Z65 Problems related to other psychosocial circumstances
0.697 0.303 0.000
Z64 Problems related to certain psychosocial circumstances
0.697 0.303 0.000
Z62 Other problems related to upbringing
0.697 0.303 0.000
Z61 Problems related to negative life events in childhood
0.697 0.303 0.000
Z59 Problems related to housing and economic circumstances
0.697 0.303 0.000
Z58 Problems related to physical environment
0.697 0.303 0.000
Z56 Problems related to employment and unemployment
0.697 0.303 0.000
Z55 Problems related to education and literacy
0.697 0.303 0.000
I49.4 Other and unspecified premature depolarisation
0.695 0.305 0.000
S62.2 Fracture of first metacarpal bone
0.695 0.305 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.695 0.305 0.000
Q21 Congenital malformations of cardiac septa
0.695 0.305 0.000
S65 Injury of blood vessels at wrist and hand level
0.694 0.305 0.000
S60 Superficial injury of wrist and hand
0.694 0.306 0.000
Z40 Prophylactic surgery
0.694 0.306 0.000
W19.2 School, other institution and public administrative area
0.694 0.306 0.000
S72 Fracture of femur
0.694 0.306 0.000
I35.9 Aortic valve disorder, unspecified
0.693 0.307 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.693 0.307 0.000
J69 Pneumonitis due to solids and liquids
0.692 0.308 0.000
M60-M63 Disorders of muscles
0.691 0.308 0.000
M00-M03 Infectious arthropathies
0.691 0.308 0.000
M24.1 Other articular cartilage disorders
0.691 0.309 0.000
L50-L54 Urticaria and erythema
0.690 0.310 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.690 0.310 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.689 0.310 0.000
F99-F99 Unspecified mental disorder
0.689 0.310 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.689 0.310 0.000
F80-F89 Disorders of psychological development
0.689 0.310 0.000
F70-F79 Mental retardation
0.689 0.310 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.689 0.310 0.000
J93 Pneumothorax
0.689 0.311 0.000
I31.3 Pericardial effusion (noninflammatory)
0.689 0.311 0.000
N37 Urethral disorders in diseases classified elsewhere
0.688 0.311 0.000
N34 Urethritis and urethral syndrome
0.688 0.311 0.000
N33 Bladder disorders in diseases classified elsewhere
0.688 0.311 0.000
Q50-Q56 Congenital malformations of genital organs
0.688 0.311 0.000
R87 Abnormal findings in specimens from female genital organs
0.688 0.312 0.000
H81 Disorders of vestibular function
0.688 0.312 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.687 0.313 0.000
J94 Other pleural conditions
0.687 0.313 0.000
Z48 Other surgical follow-up care
0.687 0.313 0.000
D55-D59 Haemolytic anaemias
0.687 0.313 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.685 0.315 0.000
S01.7 Multiple open wounds of head
0.685 0.315 0.000
S01.4 Open wound of cheek and temporomandibular area
0.685 0.315 0.000
Z51 Other medical care
0.684 0.316 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.684 0.316 0.000
R56 Convulsions, not elsewhere classified
0.684 0.316 0.000
S81 Open wound of lower leg
0.683 0.317 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.683 0.317 0.000
I42.8 Other cardiomyopathies
0.683 0.317 0.000
N18.0 End-stage renal disease
0.683 0.317 0.000
Y57 Other and unspecified drugs and medicaments
0.682 0.317 0.000
I08.0 Disorders of both mitral and aortic valves
0.682 0.318 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.682 0.318 0.000
R77 Other abnormalities of plasma proteins
0.682 0.318 0.000
R76 Other abnormal immunological findings in serum
0.682 0.318 0.000
R74 Abnormal serum enzyme levels
0.682 0.318 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.682 0.318 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.682 0.318 0.000
I45.9 Conduction disorder, unspecified
0.682 0.318 0.000
I45.8 Other specified conduction disorders
0.682 0.318 0.000
I45.6 Preexcitation syndrome
0.682 0.318 0.000
I45.5 Other specified heart block
0.682 0.318 0.000
I45.4 Nonspecific intraventricular block
0.682 0.318 0.000
I45.3 Trifascicular block
0.682 0.318 0.000
I45.2 Bifascicular block
0.682 0.318 0.000
I45.0 Right fascicular block
0.682 0.318 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.682 0.318 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.681 0.319 0.000
I84.6 Residual haemorrhoidal skin tags
0.681 0.319 0.000
B25-B34 Other viral diseases
0.680 0.320 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.680 0.320 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.680 0.320 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.680 0.320 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.680 0.320 0.000
T82.3 Mechanical complication of other vascular grafts
0.680 0.320 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.680 0.320 0.000
Z60.9 Problem related to social environment, unspecified
0.678 0.322 0.000
Z60.8 Other problems related to social environment
0.678 0.322 0.000
Z60.5 Target of perceived adverse discrimination and persecution
0.678 0.322 0.000
Z60.4 Social exclusion and rejection
0.678 0.322 0.000
Z60.3 Acculturation difficulty
0.678 0.322 0.000
Z60.1 Atypical parenting situation
0.678 0.322 0.000
Z60.0 Problems of adjustment to life-cycle transitions
0.678 0.322 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.677 0.323 0.000
N11 Chronic tubulo-interstitial nephritis
0.675 0.325 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.675 0.325 0.000
R52 Pain, not elsewhere classified
0.675 0.325 0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.675 0.325 0.000
J32.9 Chronic sinusitis, unspecified
0.674 0.326 0.000
I78.1 Naevus, nonneoplastic
0.674 0.326 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.673 0.327 0.000
M34 Systemic sclerosis
0.673 0.327 0.000
M33 Dermatopolymyositis
0.673 0.327 0.000
M32 Systemic lupus erythematosus
0.673 0.327 0.000
M30 Polyarteritis nodosa and related conditions
0.673 0.327 0.000
S51 Open wound of forearm
0.673 0.327 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.673 0.327 0.000
N00-N08 Glomerular diseases
0.672 0.328 0.000
N18.2 Chronic kidney disease, stage 2
0.672 0.328 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.672 0.328 0.000
M21.1 Varus deformity, not elsewhere classified
0.672 0.328 0.000
M05-M14 Inflammatory polyarthropathies
0.671 0.329 0.000
M85 Other disorders of bone density and structure
0.671 0.329 0.000
S62.8 Fracture of other and unspecified parts of wrist and hand
0.670 0.330 0.000
J91 Pleural effusion in conditions classified elsewhere
0.668 0.332 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.668 0.332 0.000
L03.9 Cellulitis, unspecified
0.668 0.332 0.000
Q60-Q64 Congenital malformations of the urinary system
0.667 0.333 0.000
L03.0 Cellulitis of finger and toe
0.667 0.333 0.000
W18 Other fall on same level
0.667 0.333 0.000
W17 Other fall from one level to another
0.667 0.333 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.667 0.333 0.000
W15 Fall from cliff
0.667 0.333 0.000
W14 Fall from tree
0.667 0.333 0.000
W13 Fall from, out of or through building or structure
0.667 0.333 0.000
W12 Fall on and from scaffolding
0.667 0.333 0.000
W11 Fall on and from ladder
0.667 0.333 0.000
W10 Fall on and from stairs and steps
0.667 0.333 0.000
W09 Fall involving playground equipment
0.667 0.333 0.000
W08 Fall involving other furniture
0.667 0.333 0.000
W06 Fall involving bed
0.667 0.333 0.000
W05 Fall involving wheelchair
0.667 0.333 0.000
W04 Fall while being carried or supported by other persons
0.667 0.333 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.667 0.333 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.667 0.333 0.000
W00 Fall on same level involving ice and snow
0.667 0.333 0.000
I73 Other peripheral vascular diseases
0.666 0.334 0.000
Z46.9 Fitting and adjustment of other unspecified device
0.665 0.334 0.000
Z46.8 Fitting and adjustment of other specified devices
0.665 0.334 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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