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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs115487786
log Bayes Factor = 14.3166
Chromosome 1   position 170,945,292  (GRCh37) Explore rs115487786 on Ensembl!
Variant rs115487786 is part of Cluster X0044

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
Chapter X Diseases of the respiratory system
0.999 0.001 0.000
Chapter II Neoplasms
0.998 0.002 0.000
J40-J47 Chronic lower respiratory diseases
0.992 0.008 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.984 0.016 0.000
E10-E14 Diabetes mellitus
0.981 0.019 0.000
I60-I69 Cerebrovascular diseases
0.979 0.021 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.974 0.026 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.970 0.030 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.970 0.030 0.000
E70-E90 Metabolic disorders
0.967 0.033 0.000
M70-M79 Other soft tissue disorders
0.962 0.038 0.000
I49 Other cardiac arrhythmias
0.960 0.040 0.000
M50-M54 Other dorsopathies
0.956 0.044 0.000
Chapter I Certain infectious and parasitic diseases
0.953 0.047 0.000
J44 Other chronic obstructive pulmonary disease
0.952 0.048 0.000
J90-J94 Other diseases of pleura
0.949 0.051 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.947 0.053 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.944 0.056 0.000
I50 Heart failure
0.942 0.058 0.000
Chapter XIV Diseases of the genitourinary system
0.942 0.058 0.000
I45 Other conduction disorders
0.941 0.059 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.932 0.068 0.000
L90 Atrophic disorders of skin
0.927 0.073 0.000
I35 Nonrheumatic aortic valve disorders
0.926 0.074 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.925 0.075 0.000
E11 Non-insulin-dependent diabetes mellitus
0.924 0.076 0.000
E14 Unspecified diabetes mellitus
0.922 0.078 0.000
M79.8 Other specified soft tissue disorders
0.921 0.079 0.000
J90 Pleural effusion, not elsewhere classified
0.917 0.083 0.000
M05-M14 Inflammatory polyarthropathies
0.917 0.083 0.000
Chapter VII Diseases of the eye and adnexa
0.916 0.084 0.000
M54 Dorsalgia
0.914 0.086 0.000
C78.0 Secondary malignant neoplasm of lung
0.913 0.087 0.000
E20-E35 Disorders of other endocrine glands
0.910 0.090 0.000
A00-A09 Intestinal infectious diseases
0.909 0.091 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.907 0.093 0.000
N40-N51 Diseases of male genital organs
0.906 0.094 0.000
J45 Asthma
0.901 0.099 0.000
D10-D36 Benign neoplasms
0.900 0.100 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.899 0.101 0.000
I45.1 Other and unspecified right bundle-branch block
0.898 0.102 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.898 0.102 0.000
J09-J18 Influenza and pneumonia
0.891 0.109 0.000
M20-M25 Other joint disorders
0.890 0.110 0.000
Chapter VI Diseases of the nervous system
0.887 0.113 0.000
D23 Other benign neoplasms of skin
0.886 0.114 0.000
L90.5 Scar conditions and fibrosis of skin
0.883 0.117 0.000
N48 Other disorders of penis
0.880 0.120 0.000
Chapter XX External causes of morbidity and mortality
0.879 0.121 0.000
I47 Paroxysmal tachycardia
0.874 0.126 0.000
I35.1 Aortic (valve) insufficiency
0.870 0.130 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.869 0.131 0.000
M25 Other joint disorders, not elsewhere classified
0.868 0.132 0.000
D00-D09 In situ neoplasms
0.868 0.132 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.865 0.135 0.000
M54.9 Dorsalgia, unspecified
0.861 0.139 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.860 0.140 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.859 0.141 0.000
E14.9 Without complications
0.859 0.141 0.000
M25.5 Pain in joint
0.858 0.142 0.000
D23.3 Skin of other and unspecified parts of face
0.855 0.145 0.000
H30-H36 Disorders of choroid and retina
0.854 0.146 0.000
J40 Bronchitis, not specified as acute or chronic
0.848 0.152 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.845 0.155 0.000
A04 Other bacterial intestinal infections
0.844 0.156 0.000
I50.0 Congestive heart failure
0.843 0.157 0.000
E83 Disorders of mineral metabolism
0.843 0.157 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.843 0.157 0.000
M06 Other rheumatoid arthritis
0.839 0.161 0.000
I49.8 Other specified cardiac arrhythmias
0.837 0.163 0.000
I49.5 Sick sinus syndrome
0.834 0.166 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.833 0.167 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.833 0.167 0.000
I42 Cardiomyopathy
0.833 0.167 0.000
I60 Subarachnoid haemorrhage
0.830 0.170 0.000
M79.6 Pain in limb
0.829 0.171 0.000
N30-N39 Other diseases of urinary system
0.829 0.171 0.000
M45-M49 Spondylopathies
0.826 0.174 0.000
E11.4 With neurological complications
0.825 0.175 0.000
M40-M43 Deforming dorsopathies
0.825 0.175 0.000
I46 Cardiac arrest
0.820 0.180 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.817 0.183 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.816 0.184 0.000
I67 Other cerebrovascular diseases
0.815 0.184 0.000
N48.6 Balanitis xerotica obliterans
0.815 0.185 0.000
J47 Bronchiectasis
0.814 0.186 0.000
L81 Other disorders of pigmentation
0.812 0.188 0.000
N00-N08 Glomerular diseases
0.811 0.189 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.809 0.191 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.808 0.192 0.000
I50.1 Left ventricular failure
0.806 0.194 0.000
D60-D64 Aplastic and other anaemias
0.805 0.195 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.802 0.198 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.800 0.200 0.000
J45.9 Asthma, unspecified
0.798 0.202 0.000
J18 Pneumonia, organism unspecified
0.797 0.203 0.000
E86 Volume depletion
0.796 0.204 0.000
M54.5 Low back pain
0.792 0.208 0.000
N35 Urethral stricture
0.791 0.209 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.789 0.211 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.788 0.212 0.000
M25.51 Pain in joint (Shoulder region)
0.787 0.213 0.000
C78.2 Secondary malignant neoplasm of pleura
0.785 0.215 0.000
E22 Hyperfunction of pituitary gland
0.785 0.215 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.784 0.216 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.782 0.218 0.000
E87.2 Acidosis
0.782 0.218 0.000
C78.7 Secondary malignant neoplasm of liver
0.779 0.221 0.000
M50 Cervical disk disorders
0.779 0.221 0.000
M80-M85 Disorders of bone density and structure
0.778 0.222 0.000
L20-L30 Dermatitis and eczema
0.777 0.223 0.000
I49.3 Ventricular premature depolarisation
0.775 0.225 0.000
M06.9 Rheumatoid arthritis, unspecified
0.775 0.225 0.000
I05-I09 Chronic rheumatic heart diseases
0.774 0.225 0.000
E87.7 Fluid overload
0.774 0.226 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.772 0.228 0.000
C80 Malignant neoplasm without specification of site
0.771 0.229 0.000
D23.6 Skin of upper limb, including shoulder
0.770 0.230 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.769 0.231 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.769 0.231 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.766 0.234 0.000
J30-J39 Other diseases of upper respiratory tract
0.765 0.235 0.000
D50-D53 Nutritional anaemias
0.764 0.236 0.000
N35.9 Urethral stricture, unspecified
0.764 0.236 0.000
A30-A49 Other bacterial diseases
0.761 0.239 0.000
J46 Status asthmaticus
0.760 0.239 0.000
E16 Other disorders of pancreatic internal secretion
0.760 0.239 0.000
E50-E64 Other nutritional deficiencies
0.759 0.241 0.000
E87.0 Hyperosmolality and hypernatraemia
0.758 0.241 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.756 0.244 0.000
I31 Other diseases of pericardium
0.755 0.244 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.755 0.245 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.755 0.245 0.000
M54.56 Low back pain (Lumbar region)
0.754 0.246 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.753 0.247 0.000
E87.6 Hypokalaemia
0.753 0.247 0.000
E13 Other specified diabetes mellitus
0.752 0.248 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.752 0.248 0.000
A04.8 Other specified bacterial intestinal infections
0.751 0.249 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.750 0.250 0.000
C79 Secondary malignant neoplasm of other sites
0.749 0.251 0.000
I69 Sequelae of cerebrovascular disease
0.749 0.251 0.000
N30 Cystitis
0.749 0.251 0.000
E14.3 With ophthalmic complications
0.749 0.251 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.749 0.251 0.000
L82 Seborrhoeic keratosis
0.747 0.253 0.000
L91 Hypertrophic disorders of skin
0.746 0.254 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.746 0.254 0.000
J45.0 Predominantly allergic asthma
0.742 0.258 0.000
H35 Other retinal disorders
0.741 0.259 0.000
E11.2 With renal complications
0.740 0.260 0.000
I49.0 Ventricular fibrillation and flutter
0.740 0.260 0.000
L90.0 Lichen sclerosus et atrophicus
0.740 0.260 0.000
R50-R69 General symptoms and signs
0.739 0.261 0.000
N10-N16 Renal tubulo-interstitial diseases
0.739 0.261 0.000
I61 Intracerebral haemorrhage
0.738 0.262 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.737 0.262 0.000
N17-N19 Renal failure
0.738 0.262 0.000
L50-L54 Urticaria and erythema
0.737 0.263 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.737 0.263 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.736 0.264 0.000
E87.5 Hyperkalaemia
0.735 0.265 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.734 0.266 0.000
D23.4 Skin of scalp and neck
0.734 0.266 0.000
I47.2 Ventricular tachycardia
0.733 0.267 0.000
C34 Malignant neoplasm of bronchus and lung
0.732 0.268 0.000
N48.8 Other specified disorders of penis
0.729 0.271 0.000
N48.1 Balanoposthitis
0.729 0.271 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.728 0.272 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.728 0.272 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.728 0.272 0.000
G20-G26 Extrapyramidal and movement disorders
0.728 0.272 0.000
M79.66 Pain in limb (Lower leg)
0.727 0.273 0.000
D36 Benign neoplasm of other and unspecified sites
0.726 0.274 0.000
M25.56 Pain in joint (Lower leg)
0.726 0.274 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.725 0.275 0.000
I50.9 Heart failure, unspecified
0.725 0.275 0.000
N60-N64 Disorders of breast
0.724 0.275 0.000
J00-J06 Acute upper respiratory infections
0.723 0.277 0.000
J18.1 Lobar pneumonia, unspecified
0.723 0.277 0.000
C15-C26 Malignant neoplasms of digestive organs
0.722 0.278 0.000
A08 Viral and other specified intestinal infections
0.722 0.278 0.000
M72 Fibroblastic disorders
0.717 0.283 0.000
Chapter XXII Codes for special purposes
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
I33 Acute and subacute endocarditis
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I30 Acute pericarditis
0.717 0.283 0.000
E40-E46 Malnutrition
0.717 0.283 0.000
M91-M94 Chondropathies
0.716 0.283 0.000
M60-M63 Disorders of muscles
0.716 0.283 0.000
M00-M03 Infectious arthropathies
0.716 0.283 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.716 0.284 0.000
M13 Other arthritis
0.716 0.284 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.716 0.284 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.716 0.284 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.716 0.284 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.284 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.716 0.284 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.715 0.285 0.000
J93 Pneumothorax
0.714 0.286 0.000
I47.1 Supraventricular tachycardia
0.714 0.286 0.000
N30.9 Cystitis, unspecified
0.714 0.286 0.000
I10-I15 Hypertensive diseases
0.714 0.286 0.000
M79.7 Fibromyalgia
0.713 0.287 0.000
D10 Benign neoplasm of mouth and pharynx
0.712 0.288 0.000
E11.5 With peripheral circulatory complications
0.712 0.288 0.000
J41 Simple and mucopurulent chronic bronchitis
0.711 0.289 0.000
J42 Unspecified chronic bronchitis
0.711 0.289 0.000
L85 Other epidermal thickening
0.711 0.289 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.708 0.292 0.000
E11.9 Without complications
0.708 0.292 0.000
T66-T78 Other and unspecified effects of external causes
0.708 0.292 0.000
A04.5 Campylobacter enteritis
0.707 0.293 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.707 0.293 0.000
I49.4 Other and unspecified premature depolarisation
0.707 0.293 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.705 0.295 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.705 0.295 0.000
N42 Other disorders of prostate
0.704 0.295 0.000
I44 Atrioventricular and left bundle-branch block
0.704 0.296 0.000
I46.0 Cardiac arrest with successful resuscitation
0.704 0.296 0.000
M77 Other enthesopathies
0.704 0.296 0.000
E12 Malnutrition-related diabetes mellitus
0.703 0.296 0.000
H34 Retinal vascular occlusions
0.703 0.297 0.000
M65-M68 Disorders of synovium and tendon
0.702 0.297 0.000
J20-J22 Other acute lower respiratory infections
0.703 0.297 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.702 0.298 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.702 0.298 0.000
I38 Endocarditis, valve unspecified
0.702 0.298 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.702 0.298 0.000
I65.2 Occlusion and stenosis of carotid artery
0.701 0.299 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.701 0.299 0.000
C81 Hodgkin's disease
0.700 0.300 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.700 0.300 0.000
E88 Other metabolic disorders
0.699 0.300 0.000
L10-L14 Bullous disorders
0.698 0.302 0.000
L81.4 Other melanin hyperpigmentation
0.698 0.302 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.697 0.303 0.000
I62 Other nontraumatic intracranial haemorrhage
0.696 0.303 0.000
I51 Complications and ill-defined descriptions of heart disease
0.696 0.304 0.000
E00-E07 Disorders of thyroid gland
0.696 0.304 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.696 0.304 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.696 0.304 0.000
L94 Other localised connective tissue disorders
0.696 0.304 0.000
L93 Lupus erythematosus
0.696 0.304 0.000
L87 Transepidermal elimination disorders
0.696 0.304 0.000
L88 Pyoderma gangrenosum
0.696 0.304 0.000
L86 Keratoderma in diseases classified elsewhere
0.696 0.304 0.000
L83 Acanthosis nigricans
0.696 0.304 0.000
L80 Vitiligo
0.696 0.304 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.695 0.305 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.695 0.305 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.695 0.305 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.695 0.305 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.695 0.305 0.000
M86-M90 Other osteopathies
0.695 0.305 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.695 0.305 0.000
I67.8 Other specified cerebrovascular diseases
0.695 0.305 0.000
D80-D89 Certain disorders involving the immune mechanism
0.694 0.306 0.000
E85 Amyloidosis
0.693 0.307 0.000
E84 Cystic fibrosis
0.693 0.307 0.000
E79 Disorders of purine and pyrimidine metabolism
0.693 0.307 0.000
E77 Disorders of glycoprotein metabolism
0.693 0.307 0.000
E76 Disorders of glycosaminoglycan metabolism
0.693 0.307 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.693 0.307 0.000
E74 Other disorders of carbohydrate metabolism
0.693 0.307 0.000
E73 Lactose intolerance
0.693 0.307 0.000
E72 Other disorders of amino-acid metabolism
0.693 0.307 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.693 0.307 0.000
E70 Disorders of aromatic amino-acid metabolism
0.693 0.307 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.693 0.307 0.000
M43 Other deforming dorsopathies
0.691 0.309 0.000
M34 Systemic sclerosis
0.691 0.309 0.000
C85.1 B-cell lymphoma, unspecified
0.690 0.309 0.000
M24 Other specific joint derangements
0.690 0.310 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.690 0.310 0.000
E11.3 With ophthalmic complications
0.690 0.310 0.000
M76 Enthesopathies of lower limb, excluding foot
0.689 0.310 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.689 0.310 0.000
M71 Other bursopathies
0.689 0.310 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.689 0.310 0.000
H55-H59 Other disorders of eye and adnexa
0.689 0.311 0.000
I42.0 Dilated cardiomyopathy
0.689 0.311 0.000
I49.9 Cardiac arrhythmia, unspecified
0.689 0.311 0.000
E16.2 Hypoglycaemia, unspecified
0.689 0.311 0.000
I49.2 Junctional premature depolarisation
0.688 0.312 0.000
I49.1 Atrial premature depolarisation
0.688 0.312 0.000
E27 Other disorders of adrenal gland
0.687 0.313 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.687 0.313 0.000
D23.5 Skin of trunk
0.687 0.313 0.000
B35-B49 Mycoses
0.686 0.313 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.686 0.314 0.000
M53 Other dorsopathies, not elsewhere classified
0.685 0.315 0.000
L89 Decubitus ulcer
0.685 0.315 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.684 0.315 0.000
D17 Benign lipomatous neoplasm
0.684 0.316 0.000
B99-B99 Other infectious diseases
0.684 0.316 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.684 0.316 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.684 0.316 0.000
B65-B83 Helminthiases
0.684 0.316 0.000
B50-B64 Protozoal diseases
0.684 0.316 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.684 0.316 0.000
B15-B19 Viral hepatitis
0.684 0.316 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.684 0.316 0.000
A80-A89 Viral infections of the central nervous system
0.684 0.316 0.000
A75-A79 Rickettsioses
0.684 0.316 0.000
A70-A74 Other diseases caused by chlamydiae
0.684 0.316 0.000
A65-A69 Other spirochaetal diseases
0.684 0.316 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.684 0.316 0.000
A20-A28 Certain zoonotic bacterial diseases
0.684 0.316 0.000
A15-A19 Tuberculosis
0.684 0.316 0.000
I45.6 Preexcitation syndrome
0.684 0.316 0.000
N48.4 Impotence of organic origin
0.683 0.317 0.000
D04 Carcinoma in situ of skin
0.683 0.317 0.000
E65-E68 Obesity and other hyperalimentation
0.682 0.317 0.000
D05 Carcinoma in situ of breast
0.681 0.319 0.000
H36 Retinal disorders in diseases classified elsewhere
0.681 0.319 0.000
J94 Other pleural conditions
0.681 0.319 0.000
J91 Pleural effusion in conditions classified elsewhere
0.681 0.319 0.000
C91 Lymphoid leukaemia
0.680 0.320 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.679 0.321 0.000
E83.5 Disorders of calcium metabolism
0.679 0.321 0.000
M79.9 Soft tissue disorder, unspecified
0.679 0.321 0.000
M79.5 Residual foreign body in soft tissue
0.679 0.321 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.679 0.321 0.000
M79.3 Panniculitis, unspecified
0.679 0.321 0.000
M79.2 Neuralgia and neuritis, unspecified
0.679 0.321 0.000
M79.1 Myalgia
0.679 0.321 0.000
D24 Benign neoplasm of breast
0.677 0.323 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.677 0.323 0.000
E87.4 Mixed disorder of acid-base balance
0.677 0.323 0.000
E87.3 Alkalosis
0.677 0.323 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.676 0.324 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.676 0.324 0.000
I45.9 Conduction disorder, unspecified
0.675 0.325 0.000
I45.8 Other specified conduction disorders
0.675 0.325 0.000
I45.5 Other specified heart block
0.675 0.325 0.000
I45.4 Nonspecific intraventricular block
0.675 0.325 0.000
I45.3 Trifascicular block
0.675 0.325 0.000
I45.2 Bifascicular block
0.675 0.325 0.000
I45.0 Right fascicular block
0.675 0.325 0.000
N36 Other disorders of urethra
0.675 0.325 0.000
I35.0 Aortic (valve) stenosis
0.674 0.326 0.000
J95-J99 Other diseases of the respiratory system
0.674 0.326 0.000
N25-N29 Other disorders of kidney and ureter
0.674 0.326 0.000
D32 Benign neoplasm of meninges
0.673 0.327 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.673 0.327 0.000
E21.3 Hyperparathyroidism, unspecified
0.672 0.328 0.000
E83.1 Disorders of iron metabolism
0.670 0.330 0.000
S10-S19 Injuries to the neck
0.670 0.330 0.000
L84 Corns and callosities
0.670 0.330 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.669 0.331 0.000
I26 Pulmonary embolism
0.669 0.331 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.668 0.332 0.000
C95 Leukaemia of unspecified cell type
0.668 0.332 0.000
C94 Other leukaemias of specified cell type
0.668 0.332 0.000
C93 Monocytic leukaemia
0.668 0.332 0.000
C88 Malignant immunoproliferative diseases
0.668 0.332 0.000
C86 Other specified types of T/NK-cell lymphoma
0.668 0.332 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.668 0.332 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.668 0.332 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.668 0.332 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.667 0.333 0.000
S20-S29 Injuries to the thorax
0.666 0.334 0.000
N43 Hydrocele and spermatocele
0.666 0.334 0.000
H10-H13 Disorders of conjunctiva
0.666 0.334 0.000
E83.4 Disorders of magnesium metabolism
0.665 0.335 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.665 0.335 0.000
M54.4 Lumbago with sciatica
0.665 0.335 0.000
M10 Gout
0.665 0.335 0.000
C92 Myeloid leukaemia
0.665 0.335 0.000
L90.9 Atrophic disorder of skin, unspecified
0.665 0.335 0.000
L90.8 Other atrophic disorders of skin
0.665 0.335 0.000
L90.6 Striae atrophicae
0.665 0.335 0.000
L90.4 Acrodermatitis chronica atrophicans
0.665 0.335 0.000
L90.3 Atrophoderma of Pasini and Pierini
0.665 0.335 0.000
L90.2 Anetoderma of Jadassohn-Pellizzari
0.665 0.335 0.000
L90.1 Anetoderma of Schweninger-Buzzi
0.665 0.335 0.000
M25.8 Other specified joint disorders
0.664 0.335 0.000
E23 Hypofunction and other disorders of pituitary gland
0.664 0.336 0.000
I35.9 Aortic valve disorder, unspecified
0.664 0.336 0.000
I35.8 Other aortic valve disorders
0.664 0.336 0.000
D55-D59 Haemolytic anaemias
0.663 0.337 0.000
W20-W49 Exposure to inanimate mechanical forces
0.663 0.337 0.000
E11.8 With unspecified complications
0.662 0.338 0.000
E11.7 With multiple complications
0.662 0.338 0.000
E11.6 With other specified complications
0.662 0.338 0.000
E11.1 With ketoacidosis
0.662 0.338 0.000
E11.0 With coma
0.662 0.338 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.662 0.338 0.000
E14.8 With unspecified complications
0.661 0.339 0.000
E14.7 With multiple complications
0.661 0.339 0.000
E14.6 With other specified complications
0.661 0.339 0.000
E14.5 With peripheral circulatory complications
0.661 0.339 0.000
E14.4 With neurological complications
0.661 0.339 0.000
E14.2 Withrenal complications
0.661 0.339 0.000
E14.1 With ketoacidosis
0.661 0.339 0.000
E14.0 With coma
0.661 0.339 0.000
M79.0 Rheumatism, unspecified
0.661 0.339 0.000
M79.89 Other specified soft tissue disorders (Site unspecified)
0.660 0.340 0.000
M79.88 Other specified soft tissue disorders (Other)
0.660 0.340 0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)
0.660 0.340 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.660 0.340 0.000
M79.83 Other specified soft tissue disorders (Forearm)
0.660 0.340 0.000
M79.82 Other specified soft tissue disorders (Upper arm)
0.660 0.340 0.000
M79.81 Other specified soft tissue disorders (Shoulder region)
0.660 0.340 0.000
M79.80 Other specified soft tissue disorders (Multiple sites)
0.660 0.340 0.000
M07 Psoriatic and enteropathic arthropathies
0.660 0.340 0.000
M54.1 Radiculopathy
0.660 0.340 0.000
M47 Spondylosis
0.660 0.340 0.000
M54.3 Sciatica
0.659 0.341 0.000
D23.7 Skin of lower limb, including hip
0.658 0.342 0.000
M14 Arthropathies in other diseases classified elsewhere
0.657 0.342 0.000
M12 Other specific arthropathies
0.657 0.342 0.000
M11 Other crystal arthropathies
0.657 0.342 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.657 0.342 0.000
M08 Juvenile arthritis
0.657 0.342 0.000
S50-S59 Injuries to the elbow and forearm
0.657 0.343 0.000
I95 Hypotension
0.657 0.343 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.656 0.343 0.000
V20-V29 Motorcycle rider injured in transport accident
0.656 0.344 0.000
D34 Benign neoplasm of thyroid gland
0.656 0.344 0.000
H43-H45 Disorders of vitreous body and globe
0.655 0.345 0.000
M54.8 Other dorsalgia
0.655 0.345 0.000
M54.6 Pain in thoracic spine
0.655 0.345 0.000
M54.0 Panniculitis affecting regions of neck and back
0.655 0.345 0.000
M05 Seropositive rheumatoid arthritis
0.654 0.345 0.000
D50 Iron deficiency anaemia
0.654 0.346 0.000
S00-S09 Injuries to the head
0.654 0.346 0.000
D11 Benign neoplasm of major salivary glands
0.653 0.347 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.653 0.347 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.652 0.348 0.000
E34 Other endocrine disorders
0.652 0.348 0.000
E32 Diseases of thymus
0.652 0.348 0.000
E31 Polyglandular dysfunction
0.652 0.348 0.000
E30 Disorders of puberty, not elsewhere classified
0.652 0.348 0.000
E29 Testicular dysfunction
0.652 0.348 0.000
E28 Ovarian dysfunction
0.652 0.348 0.000
E26 Hyperaldosteronism
0.652 0.348 0.000
E25 Adrenogenital disorders
0.652 0.348 0.000
E24 Cushing's syndrome
0.652 0.348 0.000
E20 Hypoparathyroidism
0.652 0.348 0.000
H25-H28 Disorders of lens
0.652 0.348 0.000
A07 Other protozoal intestinal diseases
0.652 0.348 0.000
A06 Amoebiasis
0.652 0.348 0.000
A05 Other bacterial foodborne intoxications
0.652 0.348 0.000
A03 Shigellosis
0.652 0.348 0.000
A02 Other Salmonella infections
0.652 0.348 0.000
A01 Typhoid and paratyphoid fevers
0.652 0.348 0.000
A00 Cholera
0.652 0.348 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.650 0.350 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.650 0.350 0.000
N46 Male infertility
0.650 0.350 0.000
N44 Torsion of testis
0.650 0.350 0.000
R25 Abnormal involuntary movements
0.649 0.351 0.000
R55 Syncope and collapse
0.649 0.351 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.647 0.353 0.000
R52 Pain, not elsewhere classified
0.647 0.353 0.000
N03 Chronic nephritic syndrome
0.646 0.353 0.000
J45.8 Mixed asthma
0.646 0.354 0.000
J45.1 Nonallergic asthma
0.646 0.354 0.000
M51 Other intervertebral disk disorders
0.646 0.354 0.000
D31 Benign neoplasm of eye and adnexa
0.645 0.355 0.000
D30 Benign neoplasm of urinary organs
0.645 0.355 0.000
D29 Benign neoplasm of male genital organs
0.645 0.355 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.645 0.355 0.000
D26 Other benign neoplasms of uterus
0.645 0.355 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.645 0.355 0.000
D19 Benign neoplasm of mesothelial tissue
0.645 0.355 0.000
D16 Benign neoplasm of bone and articular cartilage
0.645 0.355 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.645 0.355 0.000
I12 Hypertensive renal disease
0.644 0.356 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.643 0.357 0.000
S80-S89 Injuries to the knee and lower leg
0.643 0.357 0.000
G30-G32 Other degenerative diseases of the nervous system
0.643 0.357 0.000
H33 Retinal detachments and breaks
0.642 0.358 0.000
N02 Recurrent and persistent haematuria
0.641 0.359 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.641 0.359 0.000
J32 Chronic sinusitis
0.640 0.359 0.000
J17 Pneumonia in diseases classified elsewhere
0.639 0.361 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.639 0.361 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.639 0.361 0.000
J12 Viral pneumonia, not elsewhere classified
0.639 0.361 0.000
J11 Influenza, virus not identified
0.639 0.361 0.000
J10 Influenza due to identified influenza virus
0.639 0.361 0.000
J14 Pneumonia due to Haemophilus influenzae
0.639 0.361 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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