TreeWAS – Variant ID: rs115525301

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter X Diseases of the respiratory system	1.000	0.000
# Top node	1.000	0.000
J40-J47 Chronic lower respiratory diseases	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	1.000	0.000
Chapter VII Diseases of the eye and adnexa	0.999	0.001
Chapter XV Pregnancy, childbirth and the puerperium	0.999	0.001
J43 Emphysema	0.998	0.002
J43.9 Emphysema, unspecified	0.997	0.003
D70-D77 Other diseases of blood and blood-forming organs	0.997	0.003
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.997	0.003
H25-H28 Disorders of lens	0.994	0.006
Chapter VI Diseases of the nervous system	0.994	0.006
D70 Agranulocytosis	0.991	0.009
Chapter IV Endocrine, nutritional and metabolic diseases	0.987	0.013
J44 Other chronic obstructive pulmonary disease	0.987	0.013
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.985	0.015
H26 Other cataract	0.980	0.020
J44.9 Chronic obstructive pulmonary disease, unspecified	0.978	0.022
S00-S09 Injuries to the head	0.978	0.022
Chapter VIII Diseases of the ear and mastoid process	0.977	0.023
J90-J94 Other diseases of pleura	0.976	0.024
T81 Complications of procedures, not elsewhere classified	0.969	0.031
H26.4 After-cataract	0.967	0.033
J09-J18 Influenza and pneumonia	0.965	0.035
S01 Open wound of head	0.963	0.037
G90-G99 Other disorders of the nervous system	0.953	0.047
H90-H95 Other disorders of ear	0.949	0.051
J47 Bronchiectasis	0.942	0.058
J18 Pneumonia, organism unspecified	0.935	0.065
J95-J99 Other diseases of the respiratory system	0.930	0.070
S01.8 Open wound of other parts of head	0.930	0.070
E10-E14 Diabetes mellitus	0.927	0.073
G35-G37 Demyelinating diseases of the central nervous system	0.923	0.077
J93 Pneumothorax	0.920	0.080
T80 Complications following infusion, transfusion and therapeutic injection	0.920	0.080
O94-O99 Other obstetric conditions, not elsewhere classified	0.919	0.081
E20-E35 Disorders of other endocrine glands	0.913	0.087
H25 Senile cataract	0.906	0.094
H30-H36 Disorders of choroid and retina	0.906	0.094
E11 Non-insulin-dependent diabetes mellitus	0.905	0.095
H53-H54 Visual disturbances and blindness	0.903	0.097
T81.4 Infection following a procedure, not elsewhere classified	0.902	0.098
J18.1 Lobar pneumonia, unspecified	0.899	0.101
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.898	0.102
T85 Complications of other internal prosthetic devices, implants and grafts	0.893	0.107
D50-D53 Nutritional anaemias	0.893	0.107
D80-D89 Certain disorders involving the immune mechanism	0.893	0.107
Chapter XX External causes of morbidity and mortality	0.889	0.111
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.878	0.122
O60-O75 Complications of labour and delivery	0.877	0.123
O47 False labour	0.874	0.126
G91 Hydrocephalus	0.873	0.127
G00-G09 Inflammatory diseases of the central nervous system	0.869	0.131
H91 Other hearing loss	0.868	0.132
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.862	0.138
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.862	0.138
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.861	0.139
O48 Prolonged pregnancy	0.859	0.141
J60-J70 Lung diseases due to external agents	0.851	0.149
G35 Multiple sclerosis	0.849	0.151
E00-E07 Disorders of thyroid gland	0.847	0.153
G80-G83 Cerebral palsy and other paralytic syndromes	0.847	0.153
E11.2 With renal complications	0.846	0.154
J93.9 Pneumothorax, unspecified	0.844	0.156
O42 Premature rupture of membranes	0.844	0.156
H90 Conductive and sensorineural hearing loss	0.843	0.156
H35 Other retinal disorders	0.838	0.162
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.838	0.162
T79-T79 Certain early complications of trauma	0.835	0.165
H55-H59 Other disorders of eye and adnexa	0.833	0.167
J91 Pleural effusion in conditions classified elsewhere	0.828	0.172
O80-O84 Delivery	0.827	0.173
D73 Diseases of spleen	0.826	0.174
Chapter I Certain infectious and parasitic diseases	0.825	0.175
T80.2 Infections following infusion, transfusion and therapeutic injection	0.825	0.175
T82.1 Mechanical complication of cardiac electronic device	0.821	0.179
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.817	0.183
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.817	0.183
D86 Sarcoidosis	0.815	0.185
E21.3 Hyperparathyroidism, unspecified	0.810	0.190
H91.9 Hearing loss, unspecified	0.810	0.190
S01.9 Open wound of head, part unspecified	0.809	0.191
O30 Multiple gestation	0.808	0.192
D75 Other diseases of blood and blood-forming organs	0.807	0.193
E11.5 With peripheral circulatory complications	0.807	0.193
S01.1 Open wound of eyelid and periocular area	0.805	0.195
H25.8 Other senile cataract	0.803	0.197
G30-G32 Other degenerative diseases of the nervous system	0.802	0.198
E05 Thyrotoxicosis [hyperthyroidism]	0.800	0.200
J95 Postprocedural respiratory disorders, not elsewhere classified	0.799	0.201
D50 Iron deficiency anaemia	0.799	0.201
G91.9 Hydrocephalus, unspecified	0.798	0.202
O35 Maternal care for known or suspected foetal abnormality and damage	0.798	0.202
O47.1 False labour at or after 37 completed weeks of gestation	0.797	0.203
H26.9 Cataract, unspecified	0.797	0.203
J99 Respiratory disorders in diseases classified elsewhere	0.794	0.206
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.794	0.206
S01.2 Open wound of nose	0.791	0.209
J18.9 Pneumonia, unspecified	0.790	0.210
J94 Other pleural conditions	0.788	0.212
S01.3 Open wound of ear	0.787	0.213
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.786	0.214
H92 Otalgia and effusion of ear	0.783	0.217
O00-O08 Pregnancy with abortive outcome	0.782	0.218
H43-H45 Disorders of vitreous body and globe	0.781	0.219
G04 Encephalitis, myelitis and encephalomyelitis	0.780	0.220
H53 Visual disturbances	0.780	0.220
H25.9 Senile cataract, unspecified	0.779	0.221
H35.0 Background retinopathy and retinal vascular changes	0.773	0.227
S70-S79 Injuries to the hip and thigh	0.773	0.227
O44 Placenta praevia	0.771	0.229
T80.1 Vascular complications following infusion, transfusion and therapeutic injection	0.770	0.229
O34 Maternal care for known or suspected abnormality of pelvic organs	0.769	0.231
O85-O92 Complications predominantly related to the puerperium	0.767	0.233
S02 Fracture of skull and facial bones	0.767	0.233
H80-H83 Diseases of inner ear	0.766	0.234
J00-J06 Acute upper respiratory infections	0.765	0.235
S90-S99 Injuries to the ankle and foot	0.765	0.235
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.763	0.237
S05 Injury of eye and orbit	0.763	0.237
S40-S49 Injuries to the shoulder and upper arm	0.762	0.238
H54 Blindness and low vision	0.762	0.238
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.762	0.238
O43 Placental disorders	0.761	0.239
E11.4 With neurological complications	0.759	0.241
S10-S19 Injuries to the neck	0.759	0.241
H27 Other disorders of lens	0.758	0.242
T81.9 Unspecified complication of procedure	0.758	0.242
H65-H75 Diseases of middle ear and mastoid	0.756	0.244
E65-E68 Obesity and other hyperalimentation	0.755	0.245
J93.1 Other spontaneous pneumothorax	0.755	0.245
G93 Other disorders of brain	0.754	0.246
O63 Long labour	0.753	0.247
E05.0 Thyrotoxicosis with diffuse goitre	0.750	0.250
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.747	0.253
H46-H48 Disorders of optic nerve and visual pathways	0.747	0.253
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.746	0.254
H36 Retinal disorders in diseases classified elsewhere	0.745	0.255
G37 Other demyelinating diseases of central nervous system	0.745	0.255
G99 Other disorders of nervous system in diseases classified elsewhere	0.745	0.255
D60-D64 Aplastic and other anaemias	0.745	0.255
D50.9 Iron deficiency anaemia, unspecified	0.745	0.255
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.744	0.256
S06 Intracranial injury	0.743	0.257
J98 Other respiratory disorders	0.736	0.264
G96 Other disorders of central nervous system	0.735	0.265
G70-G73 Diseases of myoneural junction and muscle	0.734	0.266
E40-E46 Malnutrition	0.734	0.266
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.733	0.267
J90 Pleural effusion, not elsewhere classified	0.732	0.268
T81.8 Other complications of procedures, not elsewhere classified	0.731	0.269
T81.3 Disruption of operation wound, not elsewhere classified	0.730	0.270
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.729	0.271
E50-E64 Other nutritional deficiencies	0.729	0.271
D72 Other disorders of white blood cells	0.728	0.272
O20-O29 Other maternal disorders predominantly related to pregnancy	0.726	0.274
A30-A49 Other bacterial diseases	0.724	0.276
T81.7 Vascular complications following a procedure, not elsewhere classified	0.724	0.276
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.724	0.276
E11.3 With ophthalmic complications	0.724	0.276
H90.3 Sensorineural hearing loss, bilateral	0.724	0.276
J11 Influenza, virus not identified	0.723	0.277
J80-J84 Other respiratory diseases principally affecting the interstitium	0.723	0.277
J10 Influenza due to identified influenza virus	0.719	0.281
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
J41 Simple and mucopurulent chronic bronchitis	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T20-T25 Burns and corrosions of external body surface, specified by site	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
T79 Certain early complications of trauma, not elsewhere classified	0.717	0.283
D55-D59 Haemolytic anaemias	0.717	0.283
J14 Pneumonia due to Haemophilus influenzae	0.717	0.283
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.716	0.284
J43.8 Other emphysema	0.716	0.284
J43.2 Centrilobular emphysema	0.716	0.284
J43.1 Panlobular emphysema	0.716	0.284
J43.0 MacLeod's syndrome	0.716	0.284
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.716	0.284
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.715	0.285
D74 Methaemoglobinaemia	0.715	0.285
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.715	0.285
D71 Functional disorders of polymorphonuclear neutrophils	0.715	0.285
J92 Pleural plaque	0.715	0.285
T87 Complications peculiar to reattachment and amputation	0.715	0.285
H28 Cataract and other disorders of lens in diseases classified elsewhere	0.713	0.287
H60-H62 Diseases of external ear	0.712	0.288
T90 Sequelae of injuries of head	0.711	0.289
Chapter XXII Codes for special purposes	0.711	0.289
H90.5 Sensorineural hearing loss, unspecified	0.711	0.289
O42.9 Premature rupture of membranes, unspecified	0.711	0.289
H35.6 Retinal haemorrhage	0.707	0.293
O45 Premature separation of placenta [abruptio placentae]	0.706	0.294
O41 Other disorders of amniotic fluid and membranes	0.706	0.294
O33 Maternal care for known or suspected disproportion	0.706	0.294
O31 Complications specific to multiple gestation	0.706	0.294
O40 Polyhydramnios	0.706	0.294
E27 Other disorders of adrenal gland	0.704	0.296
J93.8 Other pneumothorax	0.704	0.296
H26.3 Drug-induced cataract	0.703	0.297
H26.2 Complicated cataract	0.703	0.297
H26.1 Traumatic cataract	0.703	0.297
H26.0 Infantile, juvenile and presenile cataract	0.703	0.297
H25.0 Senile incipient cataract	0.702	0.298
S08 Traumatic amputation of part of head	0.701	0.299
S07 Crushing injury of head	0.701	0.299
S04 Injury of cranial nerves	0.701	0.299
S03 Dislocation, sprain and strain of joints and ligaments of head	0.701	0.299
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.699	0.300
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.699	0.301
H35.4 Peripheral retinal degeneration	0.699	0.301
H57 Other disorders of eye and adnexa	0.698	0.301
T15-T19 Effects of foreign body entering through natural orifice	0.697	0.302
D80 Immunodeficiency with predominantly antibody defects	0.697	0.303
J99.8 Respiratory disorders in other diseases classified elsewhere	0.696	0.304
W00-W19 Falls	0.695	0.305
T81.6 Acute reaction to foreign substance accidentally left during a procedure	0.695	0.305
T81.1 Shock during or resulting from a procedure, not elsewhere classified	0.695	0.305
D51 Vitamin B12 deficiency anaemia	0.694	0.306
J02 Acute pharyngitis	0.694	0.306
J17 Pneumonia in diseases classified elsewhere	0.692	0.308
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.692	0.308
J15 Bacterial pneumonia, not elsewhere classified	0.692	0.308
J12 Viral pneumonia, not elsewhere classified	0.692	0.308
J09 Influenza due to certain identified influenza virus	0.692	0.308
J69 Pneumonitis due to solids and liquids	0.691	0.309
S80-S89 Injuries to the knee and lower leg	0.691	0.309
S01.7 Multiple open wounds of head	0.691	0.309
S01.4 Open wound of cheek and temporomandibular area	0.691	0.309
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.690	0.309
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.689	0.311
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.689	0.311
D76.3 Other histiocytosis syndromes	0.688	0.312
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.686	0.314
D86.0 Sarcoidosis of lung	0.686	0.314
E28 Ovarian dysfunction	0.686	0.314
H10-H13 Disorders of conjunctiva	0.686	0.314
G50-G59 Nerve, nerve root and plexus disorders	0.685	0.315
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.685	0.315
G91.1 Obstructive hydrocephalus	0.685	0.315
G94 Other disorders of brain in diseases classified elsewhere	0.683	0.317
G90 Disorders of autonomic nervous system	0.683	0.317
G98 Other disorders of nervous system, not elsewhere classified	0.683	0.317
G92 Toxic encephalopathy	0.683	0.317
E21.0 Primary hyperparathyroidism	0.683	0.317
H53.1 Subjective visual disturbances	0.682	0.317
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.682	0.318
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified	0.681	0.319
O30.0 Twin pregnancy	0.681	0.319
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.680	0.320
H94 Other disorders of ear in diseases classified elsewhere	0.680	0.320
T86 Failure and rejection of transplanted organs and tissues	0.678	0.322
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.677	0.323
O63.1 Prolonged second stage (of labour)	0.676	0.324
H26.8 Other specified cataract	0.675	0.324
O61 Failed induction of labour	0.675	0.325
G95 Other diseases of spinal cord	0.674	0.325
V40-V49 Car occupant injured in transport accident	0.674	0.325
T88 Other complications of surgical and medical care, not elsewhere classified	0.674	0.325
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.674	0.326
B35-B49 Mycoses	0.674	0.326
H93 Other disorders of ear, not elsewhere classified	0.673	0.326
G80 Infantile cerebral palsy	0.673	0.327
G83 Other paralytic syndromes	0.672	0.327
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.672	0.328
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.672	0.328
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.672	0.328
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.672	0.328
T82.3 Mechanical complication of other vascular grafts	0.671	0.329
J18.8 Other pneumonia, organism unspecified	0.670	0.330
J18.2 Hypostatic pneumonia, unspecified	0.670	0.330
O75 Other complications of labour and delivery, not elsewhere classified	0.670	0.330
D75.2 Essential thrombocytosis	0.669	0.331
J96 Respiratory failure, not elsewhere classified	0.667	0.333
D86.8 Sarcoidosis of other and combined sites	0.667	0.333
T92 Sequelae of injuries of upper limb	0.666	0.333
G20-G26 Extrapyramidal and movement disorders	0.666	0.334
D73.0 Hyposplenism	0.666	0.334
O00 Ectopic pregnancy	0.666	0.334
E12 Malnutrition-related diabetes mellitus	0.665	0.335
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.665	0.335
O47.9 False labour, unspecified	0.665	0.335
H43 Disorders of vitreous body	0.664	0.336
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.664	0.336
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.663	0.337
G36 Other acute disseminated demyelination	0.662	0.338
G82 Paraplegia and tetraplegia	0.661	0.339
J93.0 Spontaneous tension pneumothorax	0.660	0.340
D86.9 Sarcoidosis, unspecified	0.660	0.340
T80.9 Unspecified complication following infusion, transfusion and therapeutic injection	0.660	0.340
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.660	0.340
T80.6 Other serum reactions	0.660	0.340
T80.5 Anaphylactic shock due to serum	0.660	0.340
T80.4 Rh incompatibility reaction	0.660	0.340
T80.3 ABO incompatibility reaction	0.660	0.340
T80.0 Air embolism following infusion, transfusion and therapeutic injection	0.660	0.340
S30 Superficial injury of abdomen, lower back and pelvis	0.660	0.340
O80 Single spontaneous delivery	0.660	0.340
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.659	0.341
O97 Death from sequelae of direct obstetric causes	0.659	0.341
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.659	0.341
O95 Obstetric death of unspecified cause	0.659	0.341
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.659	0.341
J95.8 Other postprocedural respiratory disorders	0.659	0.341
O66 Other obstructed labour	0.658	0.341
J13 Pneumonia due to Streptococcus pneumoniae	0.658	0.342
O82 Single delivery by Caesarean section	0.656	0.344
E35 Disorders of endocrine glands in diseases classified elsewhere	0.655	0.345
E34 Other endocrine disorders	0.655	0.345
E32 Diseases of thymus	0.655	0.345
E31 Polyglandular dysfunction	0.655	0.345
E30 Disorders of puberty, not elsewhere classified	0.655	0.345
E26 Hyperaldosteronism	0.655	0.345
E25 Adrenogenital disorders	0.655	0.345
E24 Cushing's syndrome	0.655	0.345
E20 Hypoparathyroidism	0.655	0.345
O32 Maternal care for known or suspected malpresentation of foetus	0.654	0.346
J94.8 Other specified pleural conditions	0.654	0.346
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.653	0.347
E22 Hyperfunction of pituitary gland	0.652	0.348
H02 Other disorders of eyelid	0.652	0.348
G04.8 Other encephalitis, myelitis and encephalomyelitis	0.651	0.349
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.650	0.350
H25.2 Senile cataract, morgagnian type	0.650	0.350
H32 Chorioretinal disorders in diseases classified elsewhere	0.649	0.350
H31 Other disorders of choroid	0.649	0.350
H30 Chorioretinal inflammation	0.649	0.350
O62 Abnormalities of forces of labour	0.649	0.351
J95.0 Tracheostomy malfunction	0.649	0.351
E11.8 With unspecified complications	0.649	0.351
E11.7 With multiple complications	0.649	0.351
E11.6 With other specified complications	0.649	0.351
E11.1 With ketoacidosis	0.649	0.351
E11.0 With coma	0.649	0.351
J40 Bronchitis, not specified as acute or chronic	0.646	0.354
D73.5 Infarction of spleen	0.646	0.354
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.645	0.355
Y95 Nosocomial condition	0.645	0.355
V80-V89 Other land transport accidents	0.644	0.355
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.644	0.356
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.644	0.356
T82.4 Mechanical complication of vascular dialysis catheter	0.644	0.356
T82.0 Mechanical complication of heart valve prosthesis	0.644	0.356
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.644	0.356
J02.9 Acute pharyngitis, unspecified	0.643	0.357
J98.1 Pulmonary collapse	0.643	0.357
Y60-Y69 Misadventures to patients during surgical and medical care	0.642	0.358
H55 Nystagmus and other irregular eye movements	0.641	0.359
O36 Maternal care for other known or suspected foetal problems	0.641	0.359
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.640	0.359
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.640	0.359
T85.2 Mechanical complication of intraocular lens	0.640	0.359
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.640	0.359
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.640	0.359
H73 Other disorders of tympanic membrane	0.640	0.360
O64 Obstructed labour due to malposition and malpresentation of foetus	0.640	0.360
D53 Other nutritional anaemias	0.640	0.360
D84 Other immunodeficiencies	0.640	0.360
D83 Common variable immunodeficiency	0.640	0.360
D82 Immunodeficiency associated with other major defects	0.640	0.360
D81 Combined immunodeficiencies	0.640	0.360
H92.0 Otalgia	0.640	0.360
E03 Other hypothyroidism	0.639	0.361
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.639	0.361
O73 Retained placenta and membranes, without haemorrhage	0.638	0.362
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.637	0.362
Y35-Y36 Legal intervention and operations of war	0.637	0.362
Y10-Y34 Event of undetermined intent	0.637	0.362
Y00-Y09 Assault	0.637	0.362
X85-X99 Assault	0.637	0.362
X58-X59 Accidental exposure to other and unspecified factors	0.637	0.362
X50-X57 Overexertion, travel and privation	0.637	0.362
X40-X49 Accidental poisoning by and exposure to noxious substances	0.637	0.362
X30-X39 Exposure to forces of nature	0.637	0.362
X20-X29 Contact with venomous animals and plants	0.637	0.362
X10-X19 Contact with heat and hot substances	0.637	0.362
X00-X09 Exposure to smoke, fire and flames	0.637	0.362
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.637	0.362
W75-W84 Other accidental threats to breathing	0.637	0.362
W65-W74 Accidental drowning and submersion	0.637	0.362
W50-W64 Exposure to animate mechanical forces	0.637	0.362
V98-V99 Other and unspecified transport accidents	0.637	0.362
V95-V97 Air and space transport accidents	0.637	0.362
V90-V94 Water transport accidents	0.637	0.362
V70-V79 Bus occupant injured in transport accident	0.637	0.362
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.637	0.362
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.637	0.362
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.637	0.362
V01-V09 Pedestrian injured in transport accident	0.637	0.362
J18.0 Bronchopneumonia, unspecified	0.637	0.363
H53.4 Visual field defects	0.637	0.363
H80 Otosclerosis	0.636	0.364
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.634	0.366
H65 Nonsuppurative otitis media	0.634	0.366
J86 Pyothorax	0.633	0.367
E13 Other specified diabetes mellitus	0.632	0.368
D52 Folate deficiency anaemia	0.631	0.369
S60-S69 Injuries to the wrist and hand	0.631	0.369
J42 Unspecified chronic bronchitis	0.631	0.369
H36.0 Diabetic retinopathy	0.630	0.369
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.630	0.370
H53.8 Other visual disturbances	0.630	0.370
O72 Postpartum haemorrhage	0.630	0.370
O74 Complications of anaesthesia during labour and delivery	0.629	0.371
O71 Other obstetric trauma	0.629	0.371
O65 Obstructed labour due to maternal pelvic abnormality	0.629	0.371
O60 Preterm delivery	0.629	0.371
W20-W49 Exposure to inanimate mechanical forces	0.627	0.372
O34.7 Maternal care for abnormality of vulva and perineum	0.627	0.373
H54.7 Unspecified visual loss	0.626	0.374
G91.8 Other hydrocephalus	0.626	0.374
G91.3 Posttraumatic hydrocephalus, unspecified	0.626	0.374
G91.2 Normal-pressure hydrocephalus	0.626	0.374
G91.0 Communicating hydrocephalus	0.626	0.374
O46 Antepartum haemorrhage, not elsewhere classified	0.625	0.374
E05.9 Thyrotoxicosis, unspecified	0.625	0.375
H54.9 Unspecified visual impairment (binocular)	0.624	0.376
D75.9 Disease of blood and blood-forming organs, unspecified	0.624	0.376
Chapter XII Diseases of the skin and subcutaneous tissue	0.624	0.376
G06 Intracranial and intraspinal abscess and granuloma	0.623	0.377
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.623	0.377
G03 Meningitis due to other and unspecified causes	0.623	0.377
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.623	0.377
G00 Bacterial meningitis, not elsewhere classified	0.623	0.377
G09 Sequelae of inflammatory diseases of central nervous system	0.623	0.377
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.623	0.377
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.623	0.377
G01 Meningitis in bacterial diseases classified elsewhere	0.623	0.377
H91.8 Other specified hearing loss	0.622	0.378
H91.3 Deaf mutism, not elsewhere classified	0.622	0.378
H91.2 Sudden idiopathic hearing loss	0.622	0.378
H91.1 Presbycusis	0.622	0.378
H91.0 Ototoxic hearing loss	0.622	0.378
B95-B98 Bacterial, viral and other infectious agents	0.620	0.380
S80 Superficial injury of lower leg	0.620	0.380
O69 Labour and delivery complicated by umbilical cord complications	0.619	0.381
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.618	0.381
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.618	0.382
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.618	0.382
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.618	0.382
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.618	0.382
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.618	0.382
S46 Injury of muscle and tendon at shoulder and upper arm level	0.618	0.382
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.618	0.382
S37 Injury of urinary and pelvic organs	0.618	0.382
S36 Injury of intra-abdominal organs	0.618	0.382
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.618	0.382
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.618	0.382
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.618	0.382
S31 Open wound of abdomen, lower back and pelvis	0.618	0.382
O44.0 Placenta praevia specified as without haemorrhage	0.618	0.382
H35.9 Retinal disorder, unspecified	0.617	0.382
E21.5 Disorder of parathyroid gland, unspecified	0.617	0.383
E21.4 Other specified disorders of parathyroid gland	0.617	0.383
E21.2 Other hyperparathyroidism	0.617	0.383
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.617	0.383
S91 Open wound of ankle and foot	0.617	0.383
E14 Unspecified diabetes mellitus	0.616	0.384
E29 Testicular dysfunction	0.615	0.385
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.615	0.385
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.615	0.385
G30 Alzheimer's disease	0.611	0.389
J70 Respiratory conditions due to other external agents	0.610	0.390
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours	0.610	0.390
J67 Hypersensitivity pneumonitis due to organic dust	0.610	0.390
J66 Airway disease due to specific organic dust	0.610	0.390
J63 Pneumoconiosis due to other inorganic dusts	0.610	0.390
J62 Pneumoconiosis due to dust containing silica	0.610	0.390
J65 Pneumoconiosis associated with tuberculosis	0.610	0.390
J64 Unspecified pneumoconiosis	0.610	0.390
J60 Coalworker's pneumoconiosis	0.610	0.390
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.610	0.390
J80 Adult respiratory distress syndrome	0.610	0.390
S32 Fracture of lumbar spine and pelvis	0.609	0.391
V20-V29 Motorcycle rider injured in transport accident	0.609	0.391
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.608	0.392
E00 Congenital iodine-deficiency syndrome	0.608	0.392
E02 Subclinical iodine-deficiency hypothyroidism	0.608	0.392
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.607	0.392
Chapter V Mental and behavioural disorders	0.605	0.395
O42.2 Premature rupture of membranes, labour delayed by therapy	0.605	0.395
D61 Other aplastic anaemias	0.605	0.395
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.605	0.395
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.605	0.395
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.605	0.395
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.605	0.395
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.605	0.395
H90.0 Conductive hearing loss, bilateral	0.605	0.395
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.605	0.395
S40 Superficial injury of shoulder and upper arm	0.604	0.396
G93.1 Anoxic brain damage, not elsewhere classified	0.603	0.397
S01.5 Open wound of lip and oral cavity	0.602	0.398
O90 Complications of the puerperium, not elsewhere classified	0.601	0.398
E70-E90 Metabolic disorders	0.601	0.399
H35.7 Separation of retinal layers	0.601	0.399
H35.5 Hereditary retinal dystrophy	0.601	0.399
H35.2 Other proliferative retinopathy	0.601	0.399
H35.1 Retinopathy of prematurity	0.601	0.399

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations