TreeWAS – Variant ID: rs115551283

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000
Chapter VII Diseases of the eye and adnexa	0.999	0.001
Chapter II Neoplasms	0.999	0.001
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.998	0.002
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.997	0.003
I20-I25 Ischaemic heart diseases	0.996	0.004
Chapter I Certain infectious and parasitic diseases	0.996	0.004
I30-I52 Other forms of heart disease	0.991	0.009
D10-D36 Benign neoplasms	0.988	0.012
I25 Chronic ischaemic heart disease	0.987	0.013
C50-C50 Malignant neoplasm of breast	0.986	0.014
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.982	0.018
I25.9 Chronic ischaemic heart disease, unspecified	0.981	0.019
C50 Malignant neoplasm of breast	0.976	0.024
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.976	0.024
I20 Angina pectoris	0.965	0.035
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.962	0.038
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.962	0.038
B95-B98 Bacterial, viral and other infectious agents	0.961	0.039
I20.9 Angina pectoris, unspecified	0.957	0.043
M20-M25 Other joint disorders	0.951	0.049
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.950	0.050
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.949	0.051
M70-M79 Other soft tissue disorders	0.939	0.061
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.939	0.061
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.938	0.062
M25 Other joint disorders, not elsewhere classified	0.935	0.065
C50.4 Upper-outer quadrant of breast	0.933	0.067
A30-A49 Other bacterial diseases	0.930	0.070
C15-C26 Malignant neoplasms of digestive organs	0.928	0.072
R13 Dysphagia	0.927	0.073
M25.5 Pain in joint	0.925	0.075
M65-M68 Disorders of synovium and tendon	0.924	0.076
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.923	0.077
C50.9 Breast, unspecified	0.922	0.078
Chapter VIII Diseases of the ear and mastoid process	0.920	0.080
D22 Melanocytic naevi	0.915	0.085
H25-H28 Disorders of lens	0.912	0.088
R12 Heartburn	0.910	0.090
B35-B49 Mycoses	0.910	0.090
D27 Benign neoplasm of ovary	0.908	0.092
I42 Cardiomyopathy	0.904	0.096
D23 Other benign neoplasms of skin	0.900	0.100
Chapter XII Diseases of the skin and subcutaneous tissue	0.898	0.102
C20 Malignant neoplasm of rectum	0.893	0.107
I49 Other cardiac arrhythmias	0.891	0.109
I70-I79 Diseases of arteries, arterioles and capillaries	0.884	0.116
Chapter IV Endocrine, nutritional and metabolic diseases	0.883	0.117
M65 Synovitis and tenosynovitis	0.882	0.118
M05-M14 Inflammatory polyarthropathies	0.881	0.119
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.880	0.120
H43-H45 Disorders of vitreous body and globe	0.879	0.121
M24 Other specific joint derangements	0.878	0.122
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.876	0.124
S00-S09 Injuries to the head	0.875	0.125
I38 Endocarditis, valve unspecified	0.874	0.126
H18 Other disorders of cornea	0.874	0.126
M25.57 Pain in joint (Ankle and foot)	0.874	0.126
M75 Shoulder lesions	0.873	0.127
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.871	0.129
I44 Atrioventricular and left bundle-branch block	0.870	0.130
T92 Sequelae of injuries of upper limb	0.869	0.131
I10-I15 Hypertensive diseases	0.868	0.132
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.868	0.132
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.863	0.137
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.861	0.139
H25 Senile cataract	0.860	0.140
C90 Multiple myeloma and malignant plasma cell neoplasms	0.857	0.143
H55-H59 Other disorders of eye and adnexa	0.856	0.143
D50-D53 Nutritional anaemias	0.851	0.149
I71 Aortic aneurysm and dissection	0.848	0.152
H25.1 Senile nuclear cataract	0.842	0.158
I50 Heart failure	0.841	0.159
H20 Iridocyclitis	0.840	0.160
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.839	0.161
T93 Sequelae of injuries of lower limb	0.836	0.164
H30-H36 Disorders of choroid and retina	0.835	0.165
M65.9 Synovitis and tenosynovitis, unspecified	0.835	0.165
I22 Subsequent myocardial infarction	0.834	0.166
M79 Other soft tissue disorders, not elsewhere classified	0.834	0.166
B37 Candidiasis	0.832	0.168
D23.7 Skin of lower limb, including hip	0.829	0.171
I25.8 Other forms of chronic ischaemic heart disease	0.828	0.172
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.828	0.172
R25 Abnormal involuntary movements	0.828	0.172
D22.5 Melanocytic naevi of trunk	0.827	0.173
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.827	0.173
M75.1 Rotator cuff syndrome	0.824	0.176
A49 Bacterial infection of unspecified site	0.823	0.177
S50-S59 Injuries to the elbow and forearm	0.822	0.178
H44 Disorders of globe	0.815	0.185
I49.0 Ventricular fibrillation and flutter	0.813	0.187
D60-D64 Aplastic and other anaemias	0.809	0.191
C50.5 Lower-outer quadrant of breast	0.805	0.195
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.803	0.197
L60-L75 Disorders of skin appendages	0.803	0.197
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.802	0.198
T88 Other complications of surgical and medical care, not elsewhere classified	0.802	0.198
S32 Fracture of lumbar spine and pelvis	0.801	0.199
D28 Benign neoplasm of other and unspecified female genital organs	0.800	0.200
I50.9 Heart failure, unspecified	0.799	0.201
T80 Complications following infusion, transfusion and therapeutic injection	0.797	0.203
Chapter XX External causes of morbidity and mortality	0.797	0.203
H10-H13 Disorders of conjunctiva	0.796	0.204
Chapter XXII Codes for special purposes	0.796	0.204
D14 Benign neoplasm of middle ear and respiratory system	0.795	0.205
L80-L99 Other disorders of the skin and subcutaneous tissue	0.795	0.205
T82.1 Mechanical complication of cardiac electronic device	0.794	0.206
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.793	0.207
I25.0 Atherosclerotic cardiovascular disease, so described	0.792	0.208
S70-S79 Injuries to the hip and thigh	0.791	0.209
H21 Other disorders of iris and ciliary body	0.790	0.210
M79.8 Other specified soft tissue disorders	0.790	0.210
H16 Keratitis	0.790	0.210
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.788	0.212
D11 Benign neoplasm of major salivary glands	0.788	0.212
R25.1 Tremor, unspecified	0.788	0.212
M25.56 Pain in joint (Lower leg)	0.788	0.212
A41 Other septicaemia	0.787	0.213
S01 Open wound of head	0.786	0.214
E10-E14 Diabetes mellitus	0.784	0.216
D50 Iron deficiency anaemia	0.784	0.216
I42.2 Other hypertrophic cardiomyopathy	0.784	0.216
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters	0.780	0.220
C50.1 Central portion of breast	0.778	0.222
H17 Corneal scars and opacities	0.774	0.226
I46 Cardiac arrest	0.774	0.226
M40-M43 Deforming dorsopathies	0.773	0.227
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.772	0.228
I10 Essential (primary) hypertension	0.771	0.229
M25.53 Pain in joint (Forearm)	0.771	0.229
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.769	0.231
T90 Sequelae of injuries of head	0.768	0.232
I25.3 Aneurysm of heart	0.768	0.232
M91-M94 Chondropathies	0.765	0.235
H46-H48 Disorders of optic nerve and visual pathways	0.764	0.235
R11 Nausea and vomiting	0.764	0.236
L20-L30 Dermatitis and eczema	0.764	0.236
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.762	0.238
H18.8 Other specified disorders of cornea	0.762	0.238
H60-H62 Diseases of external ear	0.762	0.238
B15-B19 Viral hepatitis	0.761	0.239
C90.0 Multiple myeloma	0.761	0.239
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.761	0.239
R73 Elevated blood glucose level	0.760	0.240
D50.9 Iron deficiency anaemia, unspecified	0.760	0.240
T86 Failure and rejection of transplanted organs and tissues	0.759	0.241
A00-A09 Intestinal infectious diseases	0.759	0.241
D25 Leiomyoma of uterus	0.758	0.242
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.758	0.242
D22.2 Melanocytic naevi of ear and external auricular canal	0.757	0.243
M25.51 Pain in joint (Shoulder region)	0.757	0.243
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.757	0.243
L72 Follicular cysts of skin and subcutaneous tissue	0.756	0.244
H65-H75 Diseases of middle ear and mastoid	0.755	0.245
E00-E07 Disorders of thyroid gland	0.755	0.245
H44.2 Degenerative myopia	0.755	0.245
D10 Benign neoplasm of mouth and pharynx	0.754	0.245
D29 Benign neoplasm of male genital organs	0.754	0.246
I37 Pulmonary valve disorders	0.754	0.246
C92 Myeloid leukaemia	0.753	0.247
H36 Retinal disorders in diseases classified elsewhere	0.753	0.247
C64-C68 Malignant neoplasms of urinary tract	0.751	0.249
R27 Other lack of coordination	0.751	0.249
C18 Malignant neoplasm of colon	0.751	0.249
M75.0 Adhesive capsulitis of shoulder	0.750	0.250
A49.0 Staphylococcal infection, unspecified	0.749	0.251
E14 Unspecified diabetes mellitus	0.749	0.251
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters	0.748	0.252
C19 Malignant neoplasm of rectosigmoid junction	0.748	0.252
B97 Viral agents as the cause of diseases classified to other chapters	0.747	0.253
M35 Other systemic involvement of connective tissue	0.745	0.255
I35 Nonrheumatic aortic valve disorders	0.744	0.256
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.743	0.257
D80-D89 Certain disorders involving the immune mechanism	0.743	0.257
H20.9 Iridocyclitis, unspecified	0.742	0.257
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.740	0.260
I44.7 Left bundle-branch block, unspecified	0.739	0.261
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.738	0.262
R15 Faecal incontinence	0.738	0.262
C90.2 Plasmacytoma, extramedullary	0.738	0.262
D22.7 Melanocytic naevi of lower limb, including hip	0.738	0.262
D24 Benign neoplasm of breast	0.738	0.262
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.737	0.263
I44.1 Atrioventricular block, second degree	0.737	0.263
E05 Thyrotoxicosis [hyperthyroidism]	0.737	0.263
M24.0 Loose body in joint	0.736	0.264
I42.1 Obstructive hypertrophic cardiomyopathy	0.736	0.264
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.735	0.265
T66-T78 Other and unspecified effects of external causes	0.735	0.265
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.734	0.266
H05 Disorders of orbit	0.734	0.266
M06 Other rheumatoid arthritis	0.733	0.267
H55 Nystagmus and other irregular eye movements	0.732	0.267
H01 Other inflammation of eyelid	0.732	0.268
A50-A64 Infections with a predominantly sexual mode of transmission	0.731	0.269
M25.0 Haemarthrosis	0.731	0.269
T91 Sequelae of injuries of neck and trunk	0.730	0.270
H80-H83 Diseases of inner ear	0.730	0.270
S10-S19 Injuries to the neck	0.730	0.270
D33 Benign neoplasm of brain and other parts of central nervous system	0.728	0.271
I20.0 Unstable angina	0.728	0.272
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.727	0.273
M25.3 Other instability of joint	0.726	0.274
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.726	0.274
D55-D59 Haemolytic anaemias	0.725	0.275
S80-S89 Injuries to the knee and lower leg	0.725	0.275
C51-C58 Malignant neoplasms of female genital organs	0.724	0.276
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.723	0.277
T92.1 Sequelae of fracture of arm	0.722	0.278
E05.9 Thyrotoxicosis, unspecified	0.722	0.278
M00-M03 Infectious arthropathies	0.721	0.279
M50-M54 Other dorsopathies	0.719	0.281
T82.3 Mechanical complication of other vascular grafts	0.719	0.281
I49.1 Atrial premature depolarisation	0.718	0.282
M13 Other arthritis	0.718	0.282
M34 Systemic sclerosis	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
I00-I02 Acute rheumatic fever	0.717	0.283
C40-C41 Malignant neoplasms of bone and articular cartilage	0.717	0.283
M10 Gout	0.716	0.283
T33-T35 Frostbite	0.715	0.285
T26-T28 Burns and corrosions confined to eye and internal organs	0.715	0.285
T20-T25 Burns and corrosions of external body surface, specified by site	0.715	0.285
T00-T07 Injuries involving multiple body regions	0.715	0.285
D23.3 Skin of other and unspecified parts of face	0.715	0.285
M60-M63 Disorders of muscles	0.715	0.285
S00 Superficial injury of head	0.715	0.285
I23 Certain current complications following acute myocardial infarction	0.714	0.286
B99-B99 Other infectious diseases	0.714	0.286
B90-B94 Sequelae of infectious and parasitic diseases	0.714	0.286
B85-B89 Pediculosis, acariasis and other infestations	0.714	0.286
B65-B83 Helminthiases	0.714	0.286
B50-B64 Protozoal diseases	0.714	0.286
B20-B24 Human immunodeficiency virus [HIV] disease	0.714	0.286
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.714	0.286
A80-A89 Viral infections of the central nervous system	0.714	0.286
A75-A79 Rickettsioses	0.714	0.286
A70-A74 Other diseases caused by chlamydiae	0.714	0.286
A65-A69 Other spirochaetal diseases	0.714	0.286
A20-A28 Certain zoonotic bacterial diseases	0.714	0.286
A15-A19 Tuberculosis	0.714	0.286
A40 Streptococcal septicaemia	0.713	0.286
H90-H95 Other disorders of ear	0.713	0.287
R47-R49 Symptoms and signs involving speech and voice	0.713	0.287
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.713	0.287
M24.8 Other specific joint derangements, not elsewhere classified	0.712	0.288
I51 Complications and ill-defined descriptions of heart disease	0.712	0.288
M25.55 Pain in joint (Pelvic region and thigh)	0.711	0.289
M70 Soft tissue disorders related to use, overuse and pressure	0.711	0.289
H34 Retinal vascular occlusions	0.711	0.289
I52 Other heart disorders in diseases classified elsewhere	0.711	0.289
I48 Atrial fibrillation and flutter	0.711	0.289
I43 Cardiomyopathy in diseases classified elsewhere	0.711	0.289
I41 Myocarditis in diseases classified elsewhere	0.711	0.289
I40 Acute myocarditis	0.711	0.289
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.711	0.289
I36 Nonrheumatic tricuspid valve disorders	0.711	0.289
I32 Pericarditis in diseases classified elsewhere	0.711	0.289
H25.0 Senile incipient cataract	0.710	0.290
I05-I09 Chronic rheumatic heart diseases	0.709	0.291
D31 Benign neoplasm of eye and adnexa	0.709	0.291
D30 Benign neoplasm of urinary organs	0.709	0.291
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.709	0.291
D19 Benign neoplasm of mesothelial tissue	0.709	0.291
D16 Benign neoplasm of bone and articular cartilage	0.709	0.291
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.709	0.291
I25.6 Silent myocardial ischaemia	0.708	0.292
I25.4 Coronary artery aneurysm	0.708	0.292
I42.0 Dilated cardiomyopathy	0.707	0.293
C81 Hodgkin's disease	0.707	0.293
M25.6 Stiffness of joint, not elsewhere classified	0.706	0.294
M79.86 Other specified soft tissue disorders (Lower leg)	0.706	0.294
D25.0 Submucous leiomyoma of uterus	0.705	0.295
T87 Complications peculiar to reattachment and amputation	0.704	0.296
L89 Decubitus ulcer	0.703	0.297
M86-M90 Other osteopathies	0.703	0.297
I30 Acute pericarditis	0.702	0.298
C50.3 Lower-inner quadrant of breast	0.702	0.298
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified	0.701	0.299
D17 Benign lipomatous neoplasm	0.700	0.300
Chapter X Diseases of the respiratory system	0.700	0.300
C50.6 Axillary tail of breast	0.700	0.300
C50.0 Nipple and areola	0.700	0.300
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.700	0.300
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.700	0.300
H15 Disorders of sclera	0.700	0.300
B37.8 Candidiasis of other sites	0.700	0.300
S20-S29 Injuries to the thorax	0.700	0.300
I34 Nonrheumatic mitral valve disorders	0.700	0.300
H18.6 Keratoconus	0.699	0.301
R16.0 Hepatomegaly, not elsewhere classified	0.697	0.303
D70-D77 Other diseases of blood and blood-forming organs	0.697	0.303
L72.1 Trichilemmal cyst	0.696	0.304
T15-T19 Effects of foreign body entering through natural orifice	0.695	0.305
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.695	0.305
D23.9 Skin, unspecified	0.695	0.305
B37.3 Candidiasis of vulva and vagina	0.695	0.305
H36.0 Diabetic retinopathy	0.694	0.306
I47 Paroxysmal tachycardia	0.693	0.307
M24.4 Recurrent dislocation and subluxation of joint	0.692	0.308
R79 Other abnormal findings of blood chemistry	0.692	0.308
I33 Acute and subacute endocarditis	0.691	0.309
H00 Hordeolum and chalazion	0.691	0.309
T98 Sequelae of other and unspecified effects of external causes	0.689	0.310
T95 Sequelae of burns, corrosions and frostbite	0.689	0.310
T94 Sequelae of injuries involving multiple and unspecified body regions	0.689	0.310
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.689	0.310
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.689	0.310
D00-D09 In situ neoplasms	0.689	0.311
M65.4 Radial styloid tenosynovitis [de Quervain]	0.689	0.311
D23.4 Skin of scalp and neck	0.689	0.311
M21 Other acquired deformities of limbs	0.688	0.312
M25.8 Other specified joint disorders	0.688	0.312
D26 Other benign neoplasms of uterus	0.688	0.312
T92.9 Sequelae of unspecified injury of upper limb	0.688	0.312
J20-J22 Other acute lower respiratory infections	0.688	0.312
L50-L54 Urticaria and erythema	0.687	0.313
E14.3 With ophthalmic complications	0.686	0.314
A41.0 Septicaemia due to Staphylococcus aureus	0.686	0.314
D34 Benign neoplasm of thyroid gland	0.686	0.314
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.686	0.314
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.685	0.315
S01.8 Open wound of other parts of head	0.685	0.315
I44.3 Other and unspecified atrioventricular block	0.684	0.315
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.684	0.316
H18.4 Corneal degeneration	0.684	0.316
B44 Aspergillosis	0.683	0.317
S90-S99 Injuries to the ankle and foot	0.682	0.317
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.682	0.318
M33 Dermatopolymyositis	0.682	0.318
M32 Systemic lupus erythematosus	0.682	0.318
M30 Polyarteritis nodosa and related conditions	0.682	0.318
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.682	0.318
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.681	0.319
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.681	0.319
T82.4 Mechanical complication of vascular dialysis catheter	0.681	0.319
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.681	0.319
T82.0 Mechanical complication of heart valve prosthesis	0.681	0.319
Chapter VI Diseases of the nervous system	0.681	0.319
M25.54 Pain in joint (Hand)	0.681	0.319
R95-R99 Ill-defined and unknown causes of mortality	0.681	0.319
M79.83 Other specified soft tissue disorders (Forearm)	0.680	0.320
J22 Unspecified acute lower respiratory infection	0.679	0.321
D62 Acute posthaemorrhagic anaemia	0.679	0.321
R74 Abnormal serum enzyme levels	0.678	0.322
D21 Other benign neoplasms of connective and other soft tissue	0.678	0.322
B35 Dermatophytosis	0.677	0.323
M25.50 Pain in joint (Multiple sites)	0.676	0.324
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.676	0.324
T93.2 Sequelae of other fractures of lower limb	0.674	0.326
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.674	0.326
D35 Benign neoplasm of other and unspecified endocrine glands	0.674	0.326
M76 Enthesopathies of lower limb, excluding foot	0.674	0.326
M73 Soft tissue disorders in diseases classified elsewhere	0.674	0.326
M71 Other bursopathies	0.674	0.326
S32.0 Fracture of lumbar vertebra	0.673	0.327
T84.0 Mechanical complication of internal joint prosthesis	0.673	0.327
T85 Complications of other internal prosthetic devices, implants and grafts	0.673	0.327
D69 Purpura and other haemorrhagic conditions	0.672	0.328
M65.3 Trigger finger	0.671	0.328
M75.3 Calcific tendinitis of shoulder	0.671	0.329
I72 Other aneurysm	0.671	0.329
A41.9 Septicaemia, unspecified	0.671	0.329
M25.9 Joint disorder, unspecified	0.670	0.329
M25.2 Flail joint	0.670	0.329
M25.1 Fistula of joint	0.670	0.329
E20-E35 Disorders of other endocrine glands	0.668	0.332
I49.3 Ventricular premature depolarisation	0.667	0.332
T84.2 Mechanical complication of internal fixation device of other bones	0.667	0.332
R80 Isolated proteinuria	0.667	0.333
S40-S49 Injuries to the shoulder and upper arm	0.667	0.333
A48 Other bacterial diseases, not elsewhere classified	0.667	0.333
A44 Bartonellosis	0.667	0.333
A43 Nocardiosis	0.667	0.333
A42 Actinomycosis	0.667	0.333
A39 Meningococcal infection	0.667	0.333
A37 Whooping cough	0.667	0.333
A36 Diphtheria	0.667	0.333
A32 Listeriosis	0.667	0.333
A31 Infection due to other mycobacteria	0.667	0.333
A30 Leprosy [Hansen's disease]	0.667	0.333
A46 Erysipelas	0.667	0.333
A38 Scarlet fever	0.667	0.333
A35 Other tetanus	0.667	0.333
A34 Obstetrical tetanus	0.667	0.333
A33 Tetanus neonatorum	0.667	0.333
T92.2 Sequelae of fracture at wrist and hand level	0.666	0.334
M24.2 Disorder of ligament	0.665	0.334
C26 Malignant neoplasm of other and ill-defined digestive organs	0.665	0.335
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.665	0.335
C21 Malignant neoplasm of anus and anal canal	0.665	0.335
C17 Malignant neoplasm of small intestine	0.665	0.335
C23 Malignant neoplasm of gallbladder	0.665	0.335
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.664	0.336
D28.2 Uterine tubes and ligaments	0.664	0.336
S32.4 Fracture of acetabulum	0.664	0.336
M25.58 Pain in joint (Other)	0.663	0.337
M25.52 Pain in joint (Upper arm)	0.663	0.337
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.662	0.337
M66 Spontaneous rupture of synovium and tendon	0.662	0.337
M25.59 Pain in joint (Site unspecified)	0.662	0.338
S30 Superficial injury of abdomen, lower back and pelvis	0.662	0.338
M24.1 Other articular cartilage disorders	0.662	0.338
I25.2 Old myocardial infarction	0.662	0.338
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.661	0.338
C95 Leukaemia of unspecified cell type	0.661	0.338
C94 Other leukaemias of specified cell type	0.661	0.338
C93 Monocytic leukaemia	0.661	0.338
C88 Malignant immunoproliferative diseases	0.661	0.338
C86 Other specified types of T/NK-cell lymphoma	0.661	0.338
C84 Peripheral and cutaneous T-cell lymphomas	0.661	0.338
E14.9 Without complications	0.661	0.339
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters	0.661	0.339
R27.0 Ataxia, unspecified	0.661	0.339
B97.8 Other viral agents as the cause of diseases classified to other chapters	0.661	0.339
D23.6 Skin of upper limb, including shoulder	0.661	0.339
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.661	0.339
T79-T79 Certain early complications of trauma	0.660	0.339
C91 Lymphoid leukaemia	0.660	0.340
T84.1 Mechanical complication of internal fixation device of bones of limb	0.660	0.340
C50.2 Upper-inner quadrant of breast	0.660	0.340
I49.5 Sick sinus syndrome	0.659	0.341
I71.0 Dissection of aorta [any part]	0.657	0.343
M51 Other intervertebral disk disorders	0.657	0.343
S52 Fracture of forearm	0.657	0.343
D14.0 Middle ear, nasal cavity and accessory sinuses	0.656	0.343
H16.0 Corneal ulcer	0.656	0.344
D22.9 Melanocytic naevi, unspecified	0.656	0.344
D22.0 Melanocytic naevi of lip	0.656	0.344
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.656	0.344
E70-E90 Metabolic disorders	0.656	0.344
I22.0 Subsequent myocardial infarction of anterior wall	0.655	0.344
A04 Other bacterial intestinal infections	0.655	0.345
H28 Cataract and other disorders of lens in diseases classified elsewhere	0.654	0.346
H27 Other disorders of lens	0.654	0.346
B37.0 Candidal stomatitis	0.653	0.347
B48 Other mycoses, not elsewhere classified	0.652	0.348
B47 Mycetoma	0.652	0.348
B46 Zygomycosis	0.652	0.348
B45 Cryptococcosis	0.652	0.348
B43 Chromomycosis and phaeomycotic abscess	0.652	0.348
B42 Sporotrichosis	0.652	0.348
B41 Paracoccidioidomycosis	0.652	0.348
B40 Blastomycosis	0.652	0.348
B39 Histoplasmosis	0.652	0.348
B38 Coccidioidomycosis	0.652	0.348
B36 Other superficial mycoses	0.652	0.348
B49 Unspecified mycosis	0.652	0.348
I25.5 Ischaemic cardiomyopathy	0.651	0.349
D61 Other aplastic anaemias	0.651	0.349
R14 Flatulence and related conditions	0.651	0.349
H11 Other disorders of conjunctiva	0.651	0.349
H04 Disorders of lachrymal system	0.651	0.349
M35.0 Sicca syndrome [Sjogren]	0.650	0.350
R72 Abnormality of white blood cells, not elsewhere classified	0.650	0.350
I42.8 Other cardiomyopathies	0.648	0.352
I42.7 Cardiomyopathy due to drugs and other external agents	0.648	0.352
I42.6 Alcoholic cardiomyopathy	0.648	0.352
I42.5 Other restrictive cardiomyopathy	0.648	0.352
I42.4 Endocardial fibroelastosis	0.648	0.352
I42.3 Endomyocardial (eosinophilic) disease	0.648	0.352
X20-X29 Contact with venomous animals and plants	0.648	0.352
M79.2 Neuralgia and neuritis, unspecified	0.648	0.352
C18.6 Descending colon	0.648	0.352
D22.4 Melanocytic naevi of scalp and neck	0.647	0.353
D23.2 Skin of ear and external auricular canal	0.645	0.355
D23.0 Skin of lip	0.645	0.355
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.645	0.355
I22.1 Subsequent myocardial infarction of inferior wall	0.645	0.355
I49.8 Other specified cardiac arrhythmias	0.644	0.356
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.644	0.356
D11.0 Parotid gland	0.644	0.356
I42.9 Cardiomyopathy, unspecified	0.644	0.356
L10-L14 Bullous disorders	0.644	0.356
M80-M85 Disorders of bone density and structure	0.644	0.356
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.643	0.357
I22.9 Subsequent myocardial infarction of unspecified site	0.642	0.358
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.642	0.358
H53-H54 Visual disturbances and blindness	0.641	0.359
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.641	0.359
R73.0 Abnormal glucose tolerance test	0.641	0.359
D22.3 Melanocytic naevi of other and unspecified parts of face	0.640	0.360
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.640	0.360
D32 Benign neoplasm of meninges	0.640	0.360
I49.2 Junctional premature depolarisation	0.639	0.361
L82 Seborrhoeic keratosis	0.639	0.361
D36 Benign neoplasm of other and unspecified sites	0.637	0.363
D23.1 Skin of eyelid, including canthus	0.637	0.363
D22.6 Melanocytic naevi of upper limb, including shoulder	0.637	0.363
H44.0 Purulent endophthalmitis	0.637	0.363
D64 Other anaemias	0.635	0.365
M75.5 Bursitis of shoulder	0.635	0.365
H01.0 Blepharitis	0.634	0.366
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.634	0.366
C83 Diffuse non-Hodgkin's lymphoma	0.634	0.366
C43-C44 Melanoma and other malignant neoplasms of skin	0.633	0.367
E40-E46 Malnutrition	0.633	0.367
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified	0.633	0.367

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations