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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs115601504
log Bayes Factor = 13.331
Chromosome 4   position 120,816,223  (GRCh37) Explore rs115601504 on Ensembl!
Variant rs115601504 is part of Cluster X0039

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
0.999 0.001 0.000
Chapter XIV Diseases of the genitourinary system
0.999 0.001 0.000
I25.2 Old myocardial infarction
0.999 0.001 0.000
N17-N19 Renal failure
0.998 0.002 0.000
Chapter VII Diseases of the eye and adnexa
0.997 0.003 0.000
Chapter I Certain infectious and parasitic diseases
0.997 0.003 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.995 0.005 0.000
Chapter XX External causes of morbidity and mortality
0.991 0.009 0.000
N18 Chronic renal failure
0.988 0.012 0.000
Chapter VI Diseases of the nervous system
0.986 0.014 0.000
N10-N16 Renal tubulo-interstitial diseases
0.985 0.015 0.000
B95-B98 Bacterial, viral and other infectious agents
0.985 0.015 0.000
I21 Acute myocardial infarction
0.979 0.021 0.000
N19 Unspecified renal failure
0.979 0.021 0.000
N13 Obstructive and reflux uropathy
0.977 0.023 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.977 0.023 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.977 0.023 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.974 0.026 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.970 0.030 0.000
N18.3 Chronic kidney disease, stage 3
0.949 0.051 0.000
M20-M25 Other joint disorders
0.948 0.052 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.941 0.059 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.939 0.061 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.935 0.065 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.935 0.065 0.000
M25 Other joint disorders, not elsewhere classified
0.933 0.067 0.000
G90-G99 Other disorders of the nervous system
0.932 0.068 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.931 0.069 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.927 0.073 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.918 0.082 0.000
H10-H13 Disorders of conjunctiva
0.914 0.086 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.913 0.087 0.000
H30-H36 Disorders of choroid and retina
0.912 0.088 0.000
S70-S79 Injuries to the hip and thigh
0.909 0.091 0.000
M50-M54 Other dorsopathies
0.906 0.094 0.000
N20-N23 Urolithiasis
0.906 0.094 0.000
S00-S09 Injuries to the head
0.906 0.094 0.000
I30-I52 Other forms of heart disease
0.905 0.095 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.904 0.096 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.898 0.102 0.000
M23 Internal derangement of knee
0.897 0.103 0.000
M25.5 Pain in joint
0.893 0.107 0.000
B35-B49 Mycoses
0.889 0.111 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.888 0.112 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.883 0.117 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.882 0.118 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.882 0.118 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.881 0.119 0.000
Y42.7 Androgens and anabolic congeners
0.880 0.120 0.000
I77 Other disorders of arteries and arterioles
0.878 0.122 0.000
G62 Other polyneuropathies
0.875 0.125 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.873 0.127 0.000
A30-A49 Other bacterial diseases
0.870 0.130 0.000
H35 Other retinal disorders
0.870 0.130 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.865 0.135 0.000
N25-N29 Other disorders of kidney and ureter
0.863 0.137 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.861 0.139 0.000
Chapter V Mental and behavioural disorders
0.859 0.141 0.000
M86-M90 Other osteopathies
0.858 0.142 0.000
M25.56 Pain in joint (Lower leg)
0.856 0.144 0.000
I73 Other peripheral vascular diseases
0.852 0.148 0.000
I42 Cardiomyopathy
0.851 0.149 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.849 0.151 0.000
N00-N08 Glomerular diseases
0.848 0.152 0.000
H11 Other disorders of conjunctiva
0.843 0.157 0.000
I83 Varicose veins of lower extremities
0.837 0.163 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.832 0.168 0.000
N18.5 Chronic kidney disease, stage 5
0.832 0.168 0.000
N18.9 Chronic renal failure, unspecified
0.831 0.169 0.000
N13.3 Other and unspecified hydronephrosis
0.831 0.169 0.000
M50 Cervical disk disorders
0.831 0.169 0.000
G93 Other disorders of brain
0.824 0.176 0.000
S20-S29 Injuries to the thorax
0.824 0.176 0.000
H40-H42 Glaucoma
0.823 0.177 0.000
Chapter X Diseases of the respiratory system
0.823 0.177 0.000
G62.9 Polyneuropathy, unspecified
0.822 0.178 0.000
M25.7 Osteophyte
0.820 0.180 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.818 0.182 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.816 0.184 0.000
W00-W19 Falls
0.811 0.189 0.000
S09 Other and unspecified injuries of head
0.811 0.189 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.809 0.191 0.000
N18.4 Chronic kidney disease, stage 4
0.809 0.191 0.000
Chapter XXII Codes for special purposes
0.809 0.191 0.000
I71 Aortic aneurysm and dissection
0.806 0.194 0.000
I60-I69 Cerebrovascular diseases
0.806 0.194 0.000
S72 Fracture of femur
0.805 0.195 0.000
I31 Other diseases of pericardium
0.805 0.195 0.000
N13.6 Pyonephrosis
0.800 0.200 0.000
O00-O08 Pregnancy with abortive outcome
0.799 0.201 0.000
N13.4 Hydroureter
0.799 0.201 0.000
J09-J18 Influenza and pneumonia
0.798 0.202 0.000
H35.8 Other specified retinal disorders
0.797 0.203 0.000
H34 Retinal vascular occlusions
0.797 0.203 0.000
O60-O75 Complications of labour and delivery
0.797 0.203 0.000
H04 Disorders of lachrymal system
0.796 0.204 0.000
I95 Hypotension
0.796 0.204 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.796 0.204 0.000
N23 Unspecified renal colic
0.794 0.206 0.000
S50-S59 Injuries to the elbow and forearm
0.792 0.208 0.000
I74 Arterial embolism and thrombosis
0.792 0.208 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.791 0.209 0.000
M80-M85 Disorders of bone density and structure
0.790 0.210 0.000
S60-S69 Injuries to the wrist and hand
0.790 0.210 0.000
B49 Unspecified mycosis
0.789 0.211 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.787 0.213 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.786 0.214 0.000
A41 Other septicaemia
0.783 0.217 0.000
I81 Portal vein thrombosis
0.782 0.218 0.000
N18.0 End-stage renal disease
0.780 0.220 0.000
I82 Other venous embolism and thrombosis
0.777 0.223 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.776 0.224 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.775 0.225 0.000
S40-S49 Injuries to the shoulder and upper arm
0.775 0.225 0.000
I42.9 Cardiomyopathy, unspecified
0.773 0.227 0.000
H05 Disorders of orbit
0.771 0.229 0.000
Y42.5 Other oestrogens and progestogens
0.769 0.231 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.768 0.232 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.767 0.232 0.000
M51 Other intervertebral disk disorders
0.767 0.233 0.000
H20 Iridocyclitis
0.767 0.233 0.000
H35.0 Background retinopathy and retinal vascular changes
0.767 0.233 0.000
I49 Other cardiac arrhythmias
0.766 0.234 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.766 0.234 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.765 0.235 0.000
B15-B19 Viral hepatitis
0.765 0.235 0.000
H18 Other disorders of cornea
0.764 0.236 0.000
I95.1 Orthostatic hypotension
0.763 0.237 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.762 0.238 0.000
M91-M94 Chondropathies
0.761 0.239 0.000
M31 Other necrotising vasculopathies
0.759 0.241 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.759 0.241 0.000
N13.8 Other obstructive and reflux uropathy
0.758 0.242 0.000
I72 Other aneurysm
0.758 0.242 0.000
I85 Oesophageal varices
0.756 0.243 0.000
I70 Atherosclerosis
0.755 0.245 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.755 0.245 0.000
G95 Other diseases of spinal cord
0.754 0.246 0.000
D80-D89 Certain disorders involving the immune mechanism
0.753 0.247 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.753 0.247 0.000
I31.9 Disease of pericardium, unspecified
0.753 0.247 0.000
M23.8 Other internal derangements of knee
0.752 0.248 0.000
I22 Subsequent myocardial infarction
0.752 0.248 0.000
J20-J22 Other acute lower respiratory infections
0.752 0.248 0.000
M50.3 Other cervical disk degeneration
0.751 0.249 0.000
H11.4 Other conjunctival vascular disorders and cysts
0.751 0.249 0.000
Y45.0 Opioids and related analgesics
0.750 0.250 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.748 0.252 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.745 0.255 0.000
I25.5 Ischaemic cardiomyopathy
0.745 0.255 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.744 0.256 0.000
G81 Hemiplegia
0.744 0.256 0.000
H35.6 Retinal haemorrhage
0.742 0.258 0.000
H02 Other disorders of eyelid
0.742 0.258 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.741 0.259 0.000
Y52 Agents primarily affecting the cardiovascular system
0.740 0.260 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.739 0.261 0.000
S72.0 Fracture of neck of femur
0.739 0.261 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.738 0.262 0.000
M25.57 Pain in joint (Ankle and foot)
0.737 0.263 0.000
J18 Pneumonia, organism unspecified
0.737 0.263 0.000
N21 Calculus of lower urinary tract
0.737 0.263 0.000
I24 Other acute ischaemic heart diseases
0.735 0.265 0.000
S06 Intracranial injury
0.735 0.265 0.000
S20 Superficial injury of thorax
0.733 0.267 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.732 0.268 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.732 0.268 0.000
S71 Open wound of hip and thigh
0.732 0.268 0.000
M25.58 Pain in joint (Other)
0.731 0.269 0.000
S10-S19 Injuries to the neck
0.731 0.269 0.000
H55-H59 Other disorders of eye and adnexa
0.729 0.271 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.729 0.271 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.729 0.271 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.728 0.272 0.000
M23.3 Other meniscus derangements
0.728 0.272 0.000
V80-V89 Other land transport accidents
0.727 0.273 0.000
F10.3 Withdrawal state
0.727 0.273 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.725 0.275 0.000
I87 Other disorders of veins
0.724 0.275 0.000
M65-M68 Disorders of synovium and tendon
0.724 0.276 0.000
X60-X84 Intentional self-harm
0.723 0.276 0.000
G93.9 Disorder of brain, unspecified
0.723 0.277 0.000
M21 Other acquired deformities of limbs
0.722 0.277 0.000
Y40 Systemic antibiotics
0.721 0.279 0.000
I73.9 Peripheral vascular disease, unspecified
0.720 0.280 0.000
H00 Hordeolum and chalazion
0.720 0.280 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.719 0.281 0.000
I77.6 Arteritis, unspecified
0.718 0.281 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.716 0.283 0.000
I25.4 Coronary artery aneurysm
0.716 0.283 0.000
I25.3 Aneurysm of heart
0.716 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.716 0.283 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.716 0.283 0.000
N05 Unspecified nephritic syndrome
0.716 0.284 0.000
M34 Systemic sclerosis
0.715 0.284 0.000
Y44 Agents primarily affecting blood constituents
0.715 0.285 0.000
B99-B99 Other infectious diseases
0.715 0.285 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.715 0.285 0.000
B65-B83 Helminthiases
0.715 0.285 0.000
B50-B64 Protozoal diseases
0.715 0.285 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.715 0.285 0.000
A75-A79 Rickettsioses
0.715 0.285 0.000
A70-A74 Other diseases caused by chlamydiae
0.715 0.285 0.000
A65-A69 Other spirochaetal diseases
0.715 0.285 0.000
A20-A28 Certain zoonotic bacterial diseases
0.715 0.285 0.000
A15-A19 Tuberculosis
0.715 0.285 0.000
G61 Inflammatory polyneuropathy
0.714 0.286 0.000
B24 Unspecified human immunodeficiency virus [HIV] disease
0.714 0.286 0.000
M25.4 Effusion of joint
0.714 0.286 0.000
T33-T35 Frostbite
0.713 0.286 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.713 0.286 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.713 0.286 0.000
T00-T07 Injuries involving multiple body regions
0.713 0.286 0.000
T81 Complications of procedures, not elsewhere classified
0.713 0.287 0.000
M25.76 Osteophyte (Lower leg)
0.713 0.287 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.713 0.287 0.000
S79 Other and unspecified injuries of hip and thigh
0.712 0.287 0.000
G83 Other paralytic syndromes
0.712 0.288 0.000
I21.9 Acute myocardial infarction, unspecified
0.712 0.288 0.000
I21.4 Acute subendocardial myocardial infarction
0.712 0.288 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.711 0.289 0.000
M23.4 Loose body in knee
0.711 0.289 0.000
Y35-Y36 Legal intervention and operations of war
0.710 0.290 0.000
Y10-Y34 Event of undetermined intent
0.710 0.290 0.000
Y00-Y09 Assault
0.710 0.290 0.000
X85-X99 Assault
0.710 0.290 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.710 0.290 0.000
X50-X57 Overexertion, travel and privation
0.710 0.290 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.710 0.290 0.000
X30-X39 Exposure to forces of nature
0.710 0.290 0.000
X20-X29 Contact with venomous animals and plants
0.710 0.290 0.000
X10-X19 Contact with heat and hot substances
0.710 0.290 0.000
X00-X09 Exposure to smoke, fire and flames
0.710 0.290 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.710 0.290 0.000
W75-W84 Other accidental threats to breathing
0.710 0.290 0.000
W65-W74 Accidental drowning and submersion
0.710 0.290 0.000
W50-W64 Exposure to animate mechanical forces
0.710 0.290 0.000
V98-V99 Other and unspecified transport accidents
0.710 0.290 0.000
V95-V97 Air and space transport accidents
0.710 0.290 0.000
V90-V94 Water transport accidents
0.710 0.290 0.000
V70-V79 Bus occupant injured in transport accident
0.710 0.290 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.710 0.290 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.710 0.290 0.000
V40-V49 Car occupant injured in transport accident
0.710 0.290 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.710 0.290 0.000
V20-V29 Motorcycle rider injured in transport accident
0.710 0.290 0.000
V01-V09 Pedestrian injured in transport accident
0.710 0.290 0.000
M25.0 Haemarthrosis
0.710 0.290 0.000
D60-D64 Aplastic and other anaemias
0.710 0.290 0.000
J14 Pneumonia due to Haemophilus influenzae
0.709 0.291 0.000
H11.0 Pterygium
0.709 0.291 0.000
N18.8 Other chronic renal failure
0.708 0.291 0.000
N18.1 Chronic kidney disease, stage 1
0.708 0.291 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.708 0.291 0.000
M50.0 Cervical disk disorder with myelopathy
0.708 0.292 0.000
G70-G73 Diseases of myoneural junction and muscle
0.707 0.293 0.000
F10.2 Dependence syndrome
0.707 0.293 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.706 0.294 0.000
N15 Other renal tubulo-interstitial diseases
0.706 0.294 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.706 0.294 0.000
N11 Chronic tubulo-interstitial nephritis
0.706 0.294 0.000
B44 Aspergillosis
0.706 0.294 0.000
I42.2 Other hypertrophic cardiomyopathy
0.706 0.294 0.000
N02 Recurrent and persistent haematuria
0.705 0.295 0.000
S09.9 Unspecified injury of head
0.703 0.297 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.702 0.298 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.702 0.298 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.702 0.298 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.701 0.299 0.000
A80-A89 Viral infections of the central nervous system
0.701 0.299 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.700 0.299 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.700 0.299 0.000
M60-M63 Disorders of muscles
0.700 0.300 0.000
M00-M03 Infectious arthropathies
0.700 0.300 0.000
M25.8 Other specified joint disorders
0.700 0.300 0.000
H10 Conjunctivitis
0.700 0.300 0.000
T66-T78 Other and unspecified effects of external causes
0.699 0.301 0.000
H40 Glaucoma
0.699 0.301 0.000
Y59 Other and unspecified vaccines and biological substances
0.698 0.302 0.000
Y58 Bacterial vaccines
0.698 0.302 0.000
Y57 Other and unspecified drugs and medicaments
0.698 0.302 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.698 0.302 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.698 0.302 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.698 0.302 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.698 0.302 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.698 0.302 0.000
Y48 Anaesthetics and therapeutic gases
0.698 0.302 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.698 0.302 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.698 0.302 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.698 0.302 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.696 0.304 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.696 0.304 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.694 0.306 0.000
H43-H45 Disorders of vitreous body and globe
0.693 0.307 0.000
J22 Unspecified acute lower respiratory infection
0.693 0.307 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.693 0.307 0.000
S72.00 Fracture of neck of femur (closed)
0.692 0.308 0.000
Y45.2 Propionic acid derivatives
0.691 0.309 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.691 0.309 0.000
I44 Atrioventricular and left bundle-branch block
0.691 0.309 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.690 0.310 0.000
O70 Perineal laceration during delivery
0.689 0.311 0.000
J18.1 Lobar pneumonia, unspecified
0.689 0.311 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.688 0.311 0.000
N10 Acute tubulo-interstitial nephritis
0.688 0.312 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.688 0.312 0.000
S00 Superficial injury of head
0.688 0.312 0.000
W20-W49 Exposure to inanimate mechanical forces
0.687 0.312 0.000
I73.0 Raynaud's syndrome
0.687 0.313 0.000
T87 Complications peculiar to reattachment and amputation
0.687 0.313 0.000
T79-T79 Certain early complications of trauma
0.686 0.314 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.686 0.314 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.685 0.315 0.000
H01 Other inflammation of eyelid
0.685 0.315 0.000
M25.50 Pain in joint (Multiple sites)
0.684 0.316 0.000
I45 Other conduction disorders
0.684 0.316 0.000
I34 Nonrheumatic mitral valve disorders
0.683 0.317 0.000
O04 Medical abortion
0.683 0.317 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.682 0.318 0.000
M87 Osteonecrosis
0.682 0.318 0.000
V10-V19 Pedal cyclist injured in transport accident
0.682 0.318 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.680 0.320 0.000
M33 Dermatopolymyositis
0.680 0.320 0.000
M32 Systemic lupus erythematosus
0.680 0.320 0.000
M30 Polyarteritis nodosa and related conditions
0.680 0.320 0.000
H02.9 Disorder of eyelid, unspecified
0.680 0.320 0.000
S62 Fracture at wrist and hand level
0.680 0.320 0.000
N28.9 Disorder of kidney and ureter, unspecified
0.679 0.321 0.000
M90 Osteopathies in diseases classified elsewhere
0.679 0.321 0.000
M25.77 Osteophyte (Ankle and foot)
0.679 0.321 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.679 0.321 0.000
I77.8 Other specified disorders of arteries and arterioles
0.678 0.322 0.000
G30-G32 Other degenerative diseases of the nervous system
0.677 0.323 0.000
N20 Calculus of kidney and ureter
0.677 0.323 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.676 0.324 0.000
H04.2 Epiphora
0.676 0.324 0.000
Y60.0 During surgical operation
0.675 0.325 0.000
M86 Osteomyelitis
0.675 0.325 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.674 0.326 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.674 0.326 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.674 0.326 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.674 0.326 0.000
G96 Other disorders of central nervous system
0.674 0.326 0.000
G60 Hereditary and idiopathic neuropathy
0.673 0.327 0.000
G64 Other disorders of peripheral nervous system
0.673 0.327 0.000
I36 Nonrheumatic tricuspid valve disorders
0.673 0.327 0.000
O03 Spontaneous abortion
0.672 0.328 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.672 0.328 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.671 0.329 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.670 0.330 0.000
I88 Nonspecific lymphadenitis
0.670 0.330 0.000
I33 Acute and subacute endocarditis
0.669 0.330 0.000
M25.9 Joint disorder, unspecified
0.669 0.331 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.669 0.331 0.000
M25.3 Other instability of joint
0.669 0.331 0.000
M25.2 Flail joint
0.669 0.331 0.000
M25.1 Fistula of joint
0.669 0.331 0.000
H20.9 Iridocyclitis, unspecified
0.669 0.331 0.000
G91 Hydrocephalus
0.669 0.331 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.669 0.331 0.000
J95-J99 Other diseases of the respiratory system
0.668 0.332 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.668 0.332 0.000
G90 Disorders of autonomic nervous system
0.668 0.332 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.668 0.332 0.000
G92 Toxic encephalopathy
0.668 0.332 0.000
Q80-Q89 Other congenital malformations
0.668 0.332 0.000
H21 Other disorders of iris and ciliary body
0.668 0.332 0.000
Y42.9 Other and unspecified hormone antagonists
0.667 0.333 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.667 0.333 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.667 0.333 0.000
Y42.4 Oral contraceptives
0.667 0.333 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.667 0.333 0.000
Y42.2 Antithyroid drugs
0.667 0.333 0.000
Y42.1 Thyroid hormones and substitutes
0.667 0.333 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.667 0.333 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.667 0.333 0.000
S09.8 Other specified injuries of head
0.667 0.333 0.000
H34.8 Other retinal vascular occlusions
0.666 0.334 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.666 0.334 0.000
I30 Acute pericarditis
0.665 0.335 0.000
D68 Other coagulation defects
0.663 0.337 0.000
S02 Fracture of skull and facial bones
0.663 0.337 0.000
N04 Nephrotic syndrome
0.663 0.337 0.000
A41.9 Septicaemia, unspecified
0.663 0.337 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.663 0.337 0.000
F10.1 Harmful use
0.662 0.338 0.000
M51.2 Other specified intervertebral disk displacement
0.662 0.338 0.000
S80-S89 Injuries to the knee and lower leg
0.662 0.338 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.661 0.339 0.000
D86 Sarcoidosis
0.661 0.339 0.000
N26 Unspecified contracted kidney
0.661 0.339 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.660 0.340 0.000
I86 Varicose veins of other sites
0.660 0.340 0.000
G63.2 Diabetic polyneuropathy
0.660 0.340 0.000
H53-H54 Visual disturbances and blindness
0.659 0.341 0.000
G62.8 Other specified polyneuropathies
0.659 0.341 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.658 0.342 0.000
H16 Keratitis
0.658 0.342 0.000
S90-S99 Injuries to the ankle and foot
0.658 0.342 0.000
H13 Disorders of conjunctiva in diseases classified elsewhere
0.655 0.344 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.655 0.345 0.000
H05.2 Exophthalmic conditions
0.654 0.346 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.654 0.346 0.000
H31 Other disorders of choroid
0.654 0.346 0.000
H30 Chorioretinal inflammation
0.654 0.346 0.000
D69 Purpura and other haemorrhagic conditions
0.654 0.346 0.000
H34.2 Other retinal artery occlusions
0.654 0.346 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.654 0.346 0.000
N18.2 Chronic kidney disease, stage 2
0.654 0.346 0.000
Y43 Primarily systemic agents
0.654 0.346 0.000
S78 Traumatic amputation of hip and thigh
0.651 0.348 0.000
S77 Crushing injury of hip and thigh
0.651 0.348 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.651 0.348 0.000
S75 Injury of blood vessels at hip and thigh level
0.651 0.348 0.000
S74 Injury of nerves at hip and thigh level
0.651 0.348 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.651 0.348 0.000
G81.9 Hemiplegia, unspecified
0.651 0.349 0.000
W19 Unspecified fall
0.651 0.349 0.000
G97.8 Other postprocedural disorders of nervous system
0.651 0.349 0.000
M53 Other dorsopathies, not elsewhere classified
0.650 0.350 0.000
I67 Other cerebrovascular diseases
0.650 0.350 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.650 0.350 0.000
I80 Phlebitis and thrombophlebitis
0.650 0.350 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.650 0.350 0.000
S08 Traumatic amputation of part of head
0.649 0.350 0.000
S07 Crushing injury of head
0.649 0.350 0.000
S05 Injury of eye and orbit
0.649 0.350 0.000
S04 Injury of cranial nerves
0.649 0.350 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.649 0.350 0.000
G80 Infantile cerebral palsy
0.649 0.351 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.649 0.351 0.000
I52 Other heart disorders in diseases classified elsewhere
0.649 0.351 0.000
I48 Atrial fibrillation and flutter
0.649 0.351 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.649 0.351 0.000
I41 Myocarditis in diseases classified elsewhere
0.649 0.351 0.000
I40 Acute myocarditis
0.649 0.351 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.649 0.351 0.000
I37 Pulmonary valve disorders
0.649 0.351 0.000
I32 Pericarditis in diseases classified elsewhere
0.649 0.351 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.648 0.352 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.648 0.352 0.000
H17 Corneal scars and opacities
0.648 0.352 0.000
H15 Disorders of sclera
0.648 0.352 0.000
F10.9 Unspecified mental and behavioural disorder
0.647 0.352 0.000
I47 Paroxysmal tachycardia
0.647 0.353 0.000
M25.71 Osteophyte (Shoulder region)
0.647 0.353 0.000
M50.2 Other cervical disk displacement
0.646 0.354 0.000
S20.8 Superficial injuries of other and unspecified parts of thorax
0.646 0.354 0.000
I71.0 Dissection of aorta [any part]
0.646 0.354 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.645 0.355 0.000
N17 Acute renal failure
0.644 0.356 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.644 0.356 0.000
G93.6 Cerebral oedema
0.643 0.357 0.000
S60 Superficial injury of wrist and hand
0.643 0.357 0.000
M23.9 Internal derangement of knee, unspecified
0.643 0.357 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.643 0.357 0.000
M23.5 Chronic instability of knee
0.643 0.357 0.000
M23.1 Discoid meniscus (congenital)
0.643 0.357 0.000
M23.0 Cystic meniscus
0.643 0.357 0.000
I49.9 Cardiac arrhythmia, unspecified
0.642 0.358 0.000
G51 Facial nerve disorders
0.642 0.358 0.000
I46 Cardiac arrest
0.641 0.359 0.000
M25.59 Pain in joint (Site unspecified)
0.640 0.360 0.000
M25.52 Pain in joint (Upper arm)
0.640 0.360 0.000
N99-N99 Other disorders of the genitourinary system
0.640 0.360 0.000
T90 Sequelae of injuries of head
0.640 0.360 0.000
I82.9 Embolism and thrombosis of unspecified vein
0.640 0.360 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.639 0.361 0.000
H35.4 Peripheral retinal degeneration
0.639 0.361 0.000
Q60-Q64 Congenital malformations of the urinary system
0.638 0.361 0.000
F80-F89 Disorders of psychological development
0.638 0.362 0.000
M89 Other disorders of bone
0.637 0.363 0.000
B48 Other mycoses, not elsewhere classified
0.637 0.363 0.000
B47 Mycetoma
0.637 0.363 0.000
B46 Zygomycosis
0.637 0.363 0.000
B45 Cryptococcosis
0.637 0.363 0.000
B43 Chromomycosis and phaeomycotic abscess
0.637 0.363 0.000
B42 Sporotrichosis
0.637 0.363 0.000
B41 Paracoccidioidomycosis
0.637 0.363 0.000
B40 Blastomycosis
0.637 0.363 0.000
B39 Histoplasmosis
0.637 0.363 0.000
B38 Coccidioidomycosis
0.637 0.363 0.000
B36 Other superficial mycoses
0.637 0.363 0.000
D55-D59 Haemolytic anaemias
0.637 0.363 0.000
E70-E90 Metabolic disorders
0.636 0.364 0.000
F60-F69 Disorders of adult personality and behaviour
0.636 0.364 0.000
F99-F99 Unspecified mental disorder
0.635 0.365 0.000
I85.0 Oesophageal varices with bleeding
0.634 0.366 0.000
O85-O92 Complications predominantly related to the puerperium
0.633 0.367 0.000
H35.9 Retinal disorder, unspecified
0.632 0.368 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.632 0.368 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.632 0.368 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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