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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs115747344
log Bayes Factor = 17.3341
Chromosome 5   position 79,807,322  (GRCh37) Explore rs115747344 on Ensembl!
Variant rs115747344 is part of Cluster X0145

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
0.999 0.001 0.000
Chapter I Certain infectious and parasitic diseases
0.995 0.005 0.000
Chapter II Neoplasms
0.993 0.007 0.000
B95-B98 Bacterial, viral and other infectious agents
0.993 0.007 0.000
N17-N19 Renal failure
0.992 0.008 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.992 0.008 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.991 0.009 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.990 0.010 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.990 0.010 0.000
K90-K93 Other diseases of the digestive system
0.987 0.013 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.984 0.016 0.000
H25-H28 Disorders of lens
0.980 0.020 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.980 0.020 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.977 0.023 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.974 0.026 0.000
M20-M25 Other joint disorders
0.973 0.027 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.972 0.028 0.000
Chapter XX External causes of morbidity and mortality
0.971 0.029 0.000
E10-E14 Diabetes mellitus
0.969 0.031 0.000
K92 Other diseases of digestive system
0.964 0.036 0.000
N18 Chronic renal failure
0.962 0.038 0.000
C79 Secondary malignant neoplasm of other sites
0.959 0.041 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.957 0.043 0.000
K04 Diseases of pulp and periapical tissues
0.957 0.043 0.000
M23 Internal derangement of knee
0.955 0.045 0.000
K29 Gastritis and duodenitis
0.955 0.045 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.950 0.050 0.000
H25 Senile cataract
0.950 0.050 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.949 0.051 0.000
H25.1 Senile nuclear cataract
0.940 0.060 0.000
N17 Acute renal failure
0.939 0.061 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.939 0.061 0.000
E14 Unspecified diabetes mellitus
0.930 0.070 0.000
K29.7 Gastritis, unspecified
0.926 0.074 0.000
R30-R39 Symptoms and signs involving the urinary system
0.922 0.078 0.000
K92.0 Haematemesis
0.922 0.078 0.000
Chapter X Diseases of the respiratory system
0.921 0.079 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.912 0.088 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.908 0.092 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.908 0.092 0.000
N40-N51 Diseases of male genital organs
0.906 0.094 0.000
S20-S29 Injuries to the thorax
0.906 0.094 0.000
R35 Polyuria
0.905 0.095 0.000
E14.9 Without complications
0.905 0.095 0.000
K04.7 Periapical abscess without sinus
0.903 0.097 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.902 0.098 0.000
N17.9 Acute renal failure, unspecified
0.901 0.099 0.000
N18.5 Chronic kidney disease, stage 5
0.900 0.100 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.899 0.100 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.899 0.101 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.899 0.101 0.000
H30-H36 Disorders of choroid and retina
0.897 0.103 0.000
H02 Other disorders of eyelid
0.897 0.103 0.000
Chapter IX Diseases of the circulatory system
0.895 0.105 0.000
M20 Acquired deformities of fingers and toes
0.894 0.106 0.000
D60-D64 Aplastic and other anaemias
0.892 0.108 0.000
J40-J47 Chronic lower respiratory diseases
0.889 0.111 0.000
E11 Non-insulin-dependent diabetes mellitus
0.883 0.117 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.881 0.119 0.000
C15-C26 Malignant neoplasms of digestive organs
0.881 0.119 0.000
N10-N16 Renal tubulo-interstitial diseases
0.881 0.119 0.000
Chapter V Mental and behavioural disorders
0.878 0.122 0.000
O60-O75 Complications of labour and delivery
0.878 0.122 0.000
J44 Other chronic obstructive pulmonary disease
0.876 0.124 0.000
K13 Other diseases of lip and oral mucosa
0.872 0.128 0.000
R47-R49 Symptoms and signs involving speech and voice
0.868 0.132 0.000
N18.9 Chronic renal failure, unspecified
0.865 0.135 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.862 0.138 0.000
J20-J22 Other acute lower respiratory infections
0.861 0.139 0.000
K27 Peptic ulcer, site unspecified
0.860 0.140 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.859 0.141 0.000
N20-N23 Urolithiasis
0.858 0.142 0.000
E70-E90 Metabolic disorders
0.854 0.146 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.853 0.147 0.000
H26 Other cataract
0.852 0.148 0.000
B35-B49 Mycoses
0.850 0.150 0.000
I30-I52 Other forms of heart disease
0.848 0.152 0.000
K70-K77 Diseases of liver
0.846 0.154 0.000
M25 Other joint disorders, not elsewhere classified
0.845 0.155 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.844 0.156 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.843 0.157 0.000
K29.0 Acute haemorrhagic gastritis
0.841 0.159 0.000
K80 Cholelithiasis
0.840 0.160 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.835 0.165 0.000
H40-H42 Glaucoma
0.834 0.166 0.000
M05-M14 Inflammatory polyarthropathies
0.833 0.167 0.000
K20 Oesophagitis
0.833 0.167 0.000
S00-S09 Injuries to the head
0.831 0.169 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.829 0.171 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.828 0.172 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.828 0.172 0.000
R39 Other symptoms and signs involving the urinary system
0.828 0.172 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.827 0.173 0.000
D64 Other anaemias
0.827 0.173 0.000
N48 Other disorders of penis
0.824 0.176 0.000
C78.2 Secondary malignant neoplasm of pleura
0.823 0.177 0.000
H02.4 Ptosis of eyelid
0.820 0.180 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.819 0.181 0.000
J22 Unspecified acute lower respiratory infection
0.819 0.181 0.000
S50-S59 Injuries to the elbow and forearm
0.817 0.183 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.815 0.185 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.812 0.188 0.000
K04.8 Radicular cyst
0.811 0.189 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.811 0.189 0.000
K02 Dental caries
0.810 0.190 0.000
E83 Disorders of mineral metabolism
0.806 0.194 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.805 0.195 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.805 0.195 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.805 0.195 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.804 0.196 0.000
H10-H13 Disorders of conjunctiva
0.800 0.200 0.000
K29.5 Chronic gastritis, unspecified
0.800 0.200 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.799 0.201 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.799 0.201 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.797 0.203 0.000
S40-S49 Injuries to the shoulder and upper arm
0.796 0.204 0.000
H35 Other retinal disorders
0.796 0.204 0.000
M23.9 Internal derangement of knee, unspecified
0.795 0.205 0.000
R49 Voice disturbances
0.794 0.206 0.000
I60-I69 Cerebrovascular diseases
0.794 0.206 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.794 0.206 0.000
W20-W49 Exposure to inanimate mechanical forces
0.794 0.206 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.793 0.207 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.793 0.207 0.000
K92.1 Melaena
0.792 0.208 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.788 0.212 0.000
M20.5 Other deformities of toe(s) (acquired)
0.787 0.213 0.000
D69 Purpura and other haemorrhagic conditions
0.786 0.214 0.000
K07 Dentofacial anomalies [including malocclusion]
0.786 0.214 0.000
E65-E68 Obesity and other hyperalimentation
0.785 0.214 0.000
C80 Malignant neoplasm without specification of site
0.783 0.216 0.000
H02.0 Entropion and trichiasis of eyelid
0.783 0.217 0.000
M23.0 Cystic meniscus
0.782 0.218 0.000
I31 Other diseases of pericardium
0.782 0.218 0.000
D64.9 Anaemia, unspecified
0.781 0.219 0.000
M23.3 Other meniscus derangements
0.779 0.221 0.000
N99-N99 Other disorders of the genitourinary system
0.779 0.221 0.000
S10-S19 Injuries to the neck
0.776 0.224 0.000
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.776 0.224 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.775 0.225 0.000
K92.2 Gastro-intestinal haemorrhage, unspecified
0.775 0.225 0.000
K11 Diseases of salivary glands
0.775 0.225 0.000
C77.0 Lymph nodes of head, face and neck
0.775 0.225 0.000
Chapter VI Diseases of the nervous system
0.774 0.226 0.000
C20 Malignant neoplasm of rectum
0.773 0.227 0.000
R39.8 Other and unspecified symptoms and signs involving the urinary system
0.772 0.228 0.000
X60-X84 Intentional self-harm
0.772 0.228 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.771 0.229 0.000
Chapter VIII Diseases of the ear and mastoid process
0.769 0.231 0.000
N50 Other disorders of male genital organs
0.767 0.233 0.000
Y42.5 Other oestrogens and progestogens
0.767 0.233 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.765 0.234 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.765 0.235 0.000
H00 Hordeolum and chalazion
0.764 0.236 0.000
C77.1 Intrathoracic lymph nodes
0.764 0.236 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.764 0.236 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.763 0.236 0.000
N13 Obstructive and reflux uropathy
0.761 0.239 0.000
E20-E35 Disorders of other endocrine glands
0.761 0.239 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.760 0.240 0.000
K25 Gastric ulcer
0.759 0.241 0.000
S02 Fracture of skull and facial bones
0.758 0.241 0.000
M86-M90 Other osteopathies
0.758 0.242 0.000
M25.5 Pain in joint
0.755 0.245 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.755 0.245 0.000
N19 Unspecified renal failure
0.755 0.245 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.755 0.245 0.000
O80-O84 Delivery
0.754 0.245 0.000
T66-T78 Other and unspecified effects of external causes
0.753 0.247 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.753 0.247 0.000
E11.3 With ophthalmic complications
0.752 0.248 0.000
V20-V29 Motorcycle rider injured in transport accident
0.752 0.248 0.000
C78.7 Secondary malignant neoplasm of liver
0.751 0.248 0.000
N48.6 Balanitis xerotica obliterans
0.751 0.249 0.000
H25.9 Senile cataract, unspecified
0.750 0.250 0.000
O72 Postpartum haemorrhage
0.749 0.251 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.748 0.252 0.000
B37 Candidiasis
0.746 0.254 0.000
R33 Retention of urine
0.746 0.254 0.000
K29.4 Chronic atrophic gastritis
0.745 0.254 0.000
E83.5 Disorders of calcium metabolism
0.744 0.256 0.000
H53-H54 Visual disturbances and blindness
0.744 0.256 0.000
K01 Embedded and impacted teeth
0.742 0.258 0.000
R49.0 Dysphonia
0.742 0.258 0.000
H04 Disorders of lachrymal system
0.740 0.260 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.739 0.261 0.000
K10 Other diseases of jaws
0.739 0.261 0.000
K04.5 Chronic apical periodontitis
0.739 0.261 0.000
K90 Intestinal malabsorption
0.738 0.262 0.000
N20 Calculus of kidney and ureter
0.738 0.262 0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.737 0.263 0.000
K13.0 Diseases of lips
0.736 0.264 0.000
N30-N39 Other diseases of urinary system
0.736 0.264 0.000
D00-D09 In situ neoplasms
0.735 0.265 0.000
N21 Calculus of lower urinary tract
0.735 0.265 0.000
C77.3 Axillary and upper limb lymph nodes
0.734 0.266 0.000
K05 Gingivitis and periodontal diseases
0.734 0.266 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.734 0.266 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.734 0.266 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.732 0.268 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.731 0.268 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.731 0.269 0.000
N18.3 Chronic kidney disease, stage 3
0.731 0.269 0.000
M20.0 Deformity of finger(s)
0.731 0.269 0.000
N25-N29 Other disorders of kidney and ureter
0.730 0.270 0.000
K92.9 Disease of digestive system, unspecified
0.729 0.271 0.000
K12 Stomatitis and related lesions
0.729 0.271 0.000
K80.8 Other cholelithiasis
0.728 0.272 0.000
M80-M85 Disorders of bone density and structure
0.726 0.274 0.000
H35.3 Degeneration of macula and posterior pole
0.726 0.274 0.000
D80-D89 Certain disorders involving the immune mechanism
0.725 0.275 0.000
E10 Insulin-dependent diabetes mellitus
0.725 0.275 0.000
M20.1 Hallux valgus (acquired)
0.724 0.276 0.000
S90-S99 Injuries to the ankle and foot
0.724 0.276 0.000
K22 Other diseases of oesophagus
0.723 0.277 0.000
K91.3 Postoperative intestinal obstruction
0.723 0.277 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.723 0.277 0.000
K30 Dyspepsia
0.723 0.277 0.000
M45-M49 Spondylopathies
0.720 0.280 0.000
C79.2 Secondary malignant neoplasm of skin
0.720 0.280 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.719 0.281 0.000
I31.3 Pericardial effusion (noninflammatory)
0.719 0.281 0.000
I85 Oesophageal varices
0.718 0.282 0.000
K13.7 Other and unspecified lesions of oral mucosa
0.718 0.282 0.000
N42 Other disorders of prostate
0.717 0.283 0.000
B15-B19 Viral hepatitis
0.717 0.283 0.000
Chapter XXII Codes for special purposes
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
H36 Retinal disorders in diseases classified elsewhere
0.717 0.283 0.000
H55-H59 Other disorders of eye and adnexa
0.717 0.283 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.717 0.283 0.000
S22.4 Multiple fractures of ribs
0.716 0.284 0.000
H40 Glaucoma
0.715 0.285 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.715 0.285 0.000
B99-B99 Other infectious diseases
0.714 0.286 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.714 0.286 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.714 0.286 0.000
B65-B83 Helminthiases
0.714 0.286 0.000
B50-B64 Protozoal diseases
0.714 0.286 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.714 0.286 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.714 0.286 0.000
A80-A89 Viral infections of the central nervous system
0.714 0.286 0.000
A75-A79 Rickettsioses
0.714 0.286 0.000
A70-A74 Other diseases caused by chlamydiae
0.714 0.286 0.000
A65-A69 Other spirochaetal diseases
0.714 0.286 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.714 0.286 0.000
A20-A28 Certain zoonotic bacterial diseases
0.714 0.286 0.000
A15-A19 Tuberculosis
0.714 0.286 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.713 0.287 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.712 0.288 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.712 0.288 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.712 0.288 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.711 0.289 0.000
T79-T79 Certain early complications of trauma
0.711 0.289 0.000
T33-T35 Frostbite
0.711 0.289 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.711 0.289 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.711 0.289 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.711 0.289 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.711 0.289 0.000
T00-T07 Injuries involving multiple body regions
0.711 0.289 0.000
M22 Disorders of patella
0.710 0.290 0.000
K09 Cysts of oral region, not elsewhere classified
0.710 0.290 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.710 0.290 0.000
K03 Other diseases of hard tissues of teeth
0.710 0.290 0.000
K00 Disorders of tooth development and eruption
0.710 0.290 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.710 0.290 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.710 0.290 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.710 0.290 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.710 0.290 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.708 0.292 0.000
S22.3 Fracture of rib
0.707 0.293 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.707 0.293 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.707 0.293 0.000
S27 Injury of other and unspecified intrathoracic organs
0.707 0.293 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.707 0.293 0.000
I34 Nonrheumatic mitral valve disorders
0.707 0.293 0.000
K85 Acute pancreatitis
0.706 0.294 0.000
E40-E46 Malnutrition
0.705 0.295 0.000
E11.4 With neurological complications
0.705 0.295 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.704 0.296 0.000
I67 Other cerebrovascular diseases
0.704 0.296 0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.704 0.296 0.000
K83 Other diseases of biliary tract
0.704 0.296 0.000
H26.8 Other specified cataract
0.703 0.297 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.703 0.297 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.703 0.297 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.703 0.297 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.703 0.297 0.000
H27 Other disorders of lens
0.703 0.297 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.702 0.298 0.000
M91-M94 Chondropathies
0.702 0.298 0.000
M65-M68 Disorders of synovium and tendon
0.702 0.298 0.000
M60-M63 Disorders of muscles
0.702 0.298 0.000
M00-M03 Infectious arthropathies
0.702 0.298 0.000
J60-J70 Lung diseases due to external agents
0.701 0.298 0.000
N50.8 Other specified disorders of male genital organs
0.701 0.299 0.000
K28 Gastrojejunal ulcer
0.701 0.299 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.701 0.299 0.000
K86 Other diseases of pancreas
0.699 0.301 0.000
M24 Other specific joint derangements
0.698 0.302 0.000
O47 False labour
0.698 0.302 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.698 0.302 0.000
M34 Systemic sclerosis
0.698 0.302 0.000
M33 Dermatopolymyositis
0.698 0.302 0.000
M32 Systemic lupus erythematosus
0.698 0.302 0.000
M30 Polyarteritis nodosa and related conditions
0.698 0.302 0.000
M21 Other acquired deformities of limbs
0.698 0.302 0.000
J42 Unspecified chronic bronchitis
0.697 0.303 0.000
Y57 Other and unspecified drugs and medicaments
0.697 0.303 0.000
M23.8 Other internal derangements of knee
0.697 0.303 0.000
V10-V19 Pedal cyclist injured in transport accident
0.697 0.303 0.000
O85-O92 Complications predominantly related to the puerperium
0.697 0.303 0.000
Y35-Y36 Legal intervention and operations of war
0.696 0.304 0.000
Y10-Y34 Event of undetermined intent
0.696 0.304 0.000
Y00-Y09 Assault
0.696 0.304 0.000
X85-X99 Assault
0.696 0.304 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.696 0.304 0.000
X50-X57 Overexertion, travel and privation
0.696 0.304 0.000
X30-X39 Exposure to forces of nature
0.696 0.304 0.000
X20-X29 Contact with venomous animals and plants
0.696 0.304 0.000
X10-X19 Contact with heat and hot substances
0.696 0.304 0.000
X00-X09 Exposure to smoke, fire and flames
0.696 0.304 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.696 0.304 0.000
W75-W84 Other accidental threats to breathing
0.696 0.304 0.000
W65-W74 Accidental drowning and submersion
0.696 0.304 0.000
W50-W64 Exposure to animate mechanical forces
0.696 0.304 0.000
V98-V99 Other and unspecified transport accidents
0.696 0.304 0.000
V95-V97 Air and space transport accidents
0.696 0.304 0.000
V90-V94 Water transport accidents
0.696 0.304 0.000
V80-V89 Other land transport accidents
0.696 0.304 0.000
V70-V79 Bus occupant injured in transport accident
0.696 0.304 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.696 0.304 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.696 0.304 0.000
V40-V49 Car occupant injured in transport accident
0.696 0.304 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.696 0.304 0.000
V01-V09 Pedestrian injured in transport accident
0.696 0.304 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.695 0.305 0.000
I46 Cardiac arrest
0.695 0.305 0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
0.695 0.305 0.000
E13 Other specified diabetes mellitus
0.695 0.305 0.000
E12 Malnutrition-related diabetes mellitus
0.695 0.305 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.694 0.306 0.000
E11.9 Without complications
0.694 0.306 0.000
S52 Fracture of forearm
0.693 0.307 0.000
H02.8 Other specified disorders of eyelid
0.692 0.308 0.000
R80 Isolated proteinuria
0.692 0.308 0.000
K92.8 Other specified diseases of digestive system
0.691 0.308 0.000
N18.8 Other chronic renal failure
0.690 0.310 0.000
N18.2 Chronic kidney disease, stage 2
0.690 0.310 0.000
N18.1 Chronic kidney disease, stage 1
0.690 0.310 0.000
F60-F69 Disorders of adult personality and behaviour
0.690 0.310 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.689 0.311 0.000
H02.6 Xanthelasma of eyelid
0.689 0.311 0.000
C79.6 Secondary malignant neoplasm of ovary
0.687 0.312 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.687 0.312 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.687 0.312 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.687 0.312 0.000
D55-D59 Haemolytic anaemias
0.686 0.314 0.000
K04.9 Other and unspecified diseases of pulp and periapical tissues
0.686 0.314 0.000
K04.6 Periapical abscess with sinus
0.686 0.314 0.000
K04.4 Acute apical periodontitis of pulpal origin
0.686 0.314 0.000
K04.3 Abnormal hard tissue formation in pulp
0.686 0.314 0.000
K04.2 Pulp degeneration
0.686 0.314 0.000
K04.1 Necrosis of pulp
0.686 0.314 0.000
K04.0 Pulpitis
0.686 0.314 0.000
Y95 Nosocomial condition
0.686 0.314 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.685 0.315 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.685 0.315 0.000
M23.5 Chronic instability of knee
0.685 0.315 0.000
M23.4 Loose body in knee
0.685 0.315 0.000
M23.1 Discoid meniscus (congenital)
0.685 0.315 0.000
K29.9 Gastroduodenitis, unspecified
0.685 0.315 0.000
K29.3 Chronic superficial gastritis
0.685 0.315 0.000
K29.2 Alcoholic gastritis
0.685 0.315 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.684 0.316 0.000
H26.2 Complicated cataract
0.683 0.317 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.683 0.317 0.000
N18.0 End-stage renal disease
0.682 0.318 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.681 0.319 0.000
H05 Disorders of orbit
0.681 0.319 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.681 0.319 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.681 0.319 0.000
H25.2 Senile cataract, morgagnian type
0.681 0.319 0.000
O36 Maternal care for other known or suspected foetal problems
0.681 0.319 0.000
C77.4 Inguinal and lower limb lymph nodes
0.681 0.319 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.680 0.319 0.000
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)
0.680 0.320 0.000
K02.9 Dental caries, unspecified
0.680 0.320 0.000
K74 Fibrosis and cirrhosis of liver
0.680 0.320 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.680 0.320 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.679 0.321 0.000
E11.2 With renal complications
0.679 0.321 0.000
S70-S79 Injuries to the hip and thigh
0.678 0.322 0.000
N41 Inflammatory diseases of prostate
0.678 0.322 0.000
O63 Long labour
0.678 0.322 0.000
I85.9 Oesophageal varices without bleeding
0.677 0.323 0.000
Y43 Primarily systemic agents
0.677 0.323 0.000
D69.6 Thrombocytopenia, unspecified
0.676 0.324 0.000
R47 Speech disturbances, not elsewhere classified
0.676 0.324 0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome
0.675 0.325 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.675 0.325 0.000
D61 Other aplastic anaemias
0.675 0.325 0.000
F30-F39 Mood [affective] disorders
0.674 0.326 0.000
N17.8 Other acute renal failure
0.673 0.327 0.000
N17.2 Acute renal failure with medullary necrosis
0.673 0.327 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.673 0.327 0.000
N17.0 Acute renal failure with tubular necrosis
0.673 0.327 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.673 0.327 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.673 0.327 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.673 0.327 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.673 0.327 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.673 0.327 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.673 0.327 0.000
Y86 Sequelae of other accidents
0.673 0.327 0.000
C78.0 Secondary malignant neoplasm of lung
0.672 0.328 0.000
K80.2 Calculus of gallbladder without cholecystitis
0.670 0.330 0.000
C34 Malignant neoplasm of bronchus and lung
0.670 0.330 0.000
O00-O08 Pregnancy with abortive outcome
0.670 0.330 0.000
M40-M43 Deforming dorsopathies
0.669 0.331 0.000
N60-N64 Disorders of breast
0.669 0.331 0.000
N18.4 Chronic kidney disease, stage 4
0.669 0.331 0.000
C77.5 Intrapelvic lymph nodes
0.667 0.332 0.000
E14.8 With unspecified complications
0.667 0.333 0.000
E14.7 With multiple complications
0.667 0.333 0.000
E14.6 With other specified complications
0.667 0.333 0.000
E14.5 With peripheral circulatory complications
0.667 0.333 0.000
E14.4 With neurological complications
0.667 0.333 0.000
E14.2 Withrenal complications
0.667 0.333 0.000
E14.1 With ketoacidosis
0.667 0.333 0.000
E14.0 With coma
0.667 0.333 0.000
W22 Striking against or struck by other objects
0.667 0.333 0.000
Y44 Agents primarily affecting blood constituents
0.666 0.334 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.666 0.334 0.000
E83.4 Disorders of magnesium metabolism
0.665 0.335 0.000
M06 Other rheumatoid arthritis
0.665 0.335 0.000
K26 Duodenal ulcer
0.663 0.337 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.662 0.338 0.000
E87.7 Fluid overload
0.662 0.338 0.000
R36 Urethral discharge
0.661 0.339 0.000
R34 Anuria and oliguria
0.661 0.339 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.661 0.339 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.660 0.339 0.000
K25.3 Acute without haemorrhage or perforation
0.660 0.340 0.000
N70 Salpingitis and oophoritis
0.659 0.341 0.000
M05 Seropositive rheumatoid arthritis
0.659 0.341 0.000
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)
0.658 0.341 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.658 0.341 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.658 0.342 0.000
H11 Other disorders of conjunctiva
0.657 0.343 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.657 0.343 0.000
H26.9 Cataract, unspecified
0.657 0.343 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.655 0.344 0.000
H33 Retinal detachments and breaks
0.654 0.345 0.000
Y59 Other and unspecified vaccines and biological substances
0.654 0.346 0.000
Y58 Bacterial vaccines
0.654 0.346 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.654 0.346 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.654 0.346 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.654 0.346 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.654 0.346 0.000
Y52 Agents primarily affecting the cardiovascular system
0.654 0.346 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.654 0.346 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.654 0.346 0.000
Y48 Anaesthetics and therapeutic gases
0.654 0.346 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.654 0.346 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.654 0.346 0.000
Y40 Systemic antibiotics
0.654 0.346 0.000
N39 Other disorders of urinary system
0.654 0.346 0.000
I38 Endocarditis, valve unspecified
0.653 0.347 0.000
H40.2 Primary angle-closure glaucoma
0.653 0.347 0.000
S06 Intracranial injury
0.653 0.347 0.000
H00.0 Hordeolum and other deep inflammation of eyelid
0.653 0.347 0.000
E83.3 Disorders of phosphorus metabolism
0.652 0.348 0.000
M25.7 Osteophyte
0.652 0.348 0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.652 0.348 0.000
H43-H45 Disorders of vitreous body and globe
0.651 0.349 0.000
J43 Emphysema
0.651 0.349 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.651 0.349 0.000
M20.4 Other hammer toe(s) (acquired)
0.651 0.349 0.000
C77.9 Lymph node, unspecified
0.651 0.349 0.000
C77.8 Lymph nodes of multiple regions
0.651 0.349 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.651 0.349 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.651 0.349 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.650 0.350 0.000
K76 Other diseases of liver
0.650 0.350 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.650 0.350 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.650 0.350 0.000
N46 Male infertility
0.650 0.350 0.000
N44 Torsion of testis
0.650 0.350 0.000
S29 Other and unspecified injuries of thorax
0.650 0.350 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.650 0.350 0.000
S26 Injury of heart
0.650 0.350 0.000
S25 Injury of blood vessels of thorax
0.650 0.350 0.000
S24 Injury of nerves and spinal cord at thorax level
0.650 0.350 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.650 0.350 0.000
S21 Open wound of thorax
0.650 0.350 0.000
S20 Superficial injury of thorax
0.650 0.350 0.000
H02.5 Other disorders affecting eyelid function
0.649 0.351 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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