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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs116144413
log Bayes Factor = 13.7612
Chromosome 4   position 946,403  (GRCh37) Explore rs116144413 on Ensembl!
Variant rs116144413 is part of Cluster X0069

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
S50-S59 Injuries to the elbow and forearm
0.999 0.001 0.000
I25 Chronic ischaemic heart disease
0.999 0.001 0.000
I21 Acute myocardial infarction
0.999 0.001 0.000
S52 Fracture of forearm
0.998 0.002 0.000
Chapter IX Diseases of the circulatory system
0.998 0.002 0.000
O60-O75 Complications of labour and delivery
0.997 0.003 0.000
I25.2 Old myocardial infarction
0.995 0.005 0.000
Chapter VII Diseases of the eye and adnexa
0.995 0.005 0.000
I20 Angina pectoris
0.994 0.006 0.000
S52.5 Fracture of lower end of radius
0.994 0.006 0.000
O63 Long labour
0.992 0.008 0.000
Chapter XX External causes of morbidity and mortality
0.991 0.009 0.000
S52.50 Fracture of lower end of radius (closed)
0.991 0.009 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.984 0.016 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.983 0.017 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.979 0.021 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.979 0.021 0.000
H30-H36 Disorders of choroid and retina
0.977 0.023 0.000
Chapter XXII Codes for special purposes
0.977 0.023 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.976 0.024 0.000
I21.9 Acute myocardial infarction, unspecified
0.975 0.025 0.000
H02 Other disorders of eyelid
0.966 0.034 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.964 0.036 0.000
I25.1 Atherosclerotic heart disease
0.963 0.037 0.000
I20.8 Other forms of angina pectoris
0.961 0.039 0.000
O63.1 Prolonged second stage (of labour)
0.959 0.041 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.955 0.045 0.000
H02.0 Entropion and trichiasis of eyelid
0.955 0.045 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.955 0.045 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.952 0.048 0.000
T90 Sequelae of injuries of head
0.952 0.048 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.951 0.049 0.000
M45-M49 Spondylopathies
0.948 0.052 0.000
O48 Prolonged pregnancy
0.948 0.052 0.000
S70-S79 Injuries to the hip and thigh
0.941 0.059 0.000
H33 Retinal detachments and breaks
0.935 0.065 0.000
Y86 Sequelae of other accidents
0.934 0.066 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.929 0.071 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.928 0.072 0.000
M48 Other spondylopathies
0.926 0.074 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.923 0.077 0.000
M50-M54 Other dorsopathies
0.919 0.081 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.918 0.082 0.000
E20-E35 Disorders of other endocrine glands
0.917 0.083 0.000
H34 Retinal vascular occlusions
0.916 0.084 0.000
O63.0 Prolonged first stage (of labour)
0.916 0.084 0.000
S52.0 Fracture of upper end of ulna
0.914 0.086 0.000
E10-E14 Diabetes mellitus
0.913 0.087 0.000
S51 Open wound of forearm
0.912 0.088 0.000
M48.0 Spinal stenosis
0.912 0.088 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.909 0.091 0.000
S80-S89 Injuries to the knee and lower leg
0.904 0.096 0.000
O00-O08 Pregnancy with abortive outcome
0.899 0.101 0.000
M48.06 Spinal stenosis (Lumbar region)
0.897 0.103 0.000
U80 Agent resistant to penicillin and related antibiotics
0.897 0.103 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.896 0.104 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.893 0.107 0.000
E10 Insulin-dependent diabetes mellitus
0.892 0.108 0.000
S40-S49 Injuries to the shoulder and upper arm
0.891 0.109 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.891 0.109 0.000
M50 Cervical disk disorders
0.891 0.109 0.000
T39.1 4-Aminophenol derivatives
0.888 0.112 0.000
I22 Subsequent myocardial infarction
0.888 0.112 0.000
S72 Fracture of femur
0.887 0.113 0.000
I20.0 Unstable angina
0.887 0.113 0.000
H33.3 Retinal breaks without detachment
0.886 0.114 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.885 0.115 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.883 0.117 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.883 0.117 0.000
O63.9 Long labour, unspecified
0.883 0.117 0.000
I20.9 Angina pectoris, unspecified
0.881 0.119 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.869 0.131 0.000
M50.3 Other cervical disk degeneration
0.869 0.131 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.867 0.133 0.000
O36 Maternal care for other known or suspected foetal problems
0.867 0.133 0.000
M86-M90 Other osteopathies
0.858 0.142 0.000
H33.0 Retinal detachment with retinal break
0.850 0.150 0.000
U80.1 Methicillin resistant agent
0.847 0.153 0.000
W20-W49 Exposure to inanimate mechanical forces
0.847 0.153 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.845 0.155 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.844 0.156 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.843 0.157 0.000
H34.2 Other retinal artery occlusions
0.840 0.160 0.000
T90.4 Sequelae of injury of eye and orbit
0.833 0.167 0.000
S52.00 Fracture of upper end of ulna (closed)
0.830 0.170 0.000
S42 Fracture of shoulder and upper arm
0.829 0.171 0.000
E10.9 Without complications
0.828 0.172 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.828 0.172 0.000
S10-S19 Injuries to the neck
0.827 0.173 0.000
V10-V19 Pedal cyclist injured in transport accident
0.825 0.175 0.000
T92 Sequelae of injuries of upper limb
0.825 0.175 0.000
M60-M63 Disorders of muscles
0.815 0.185 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.814 0.186 0.000
I24 Other acute ischaemic heart diseases
0.813 0.187 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.812 0.188 0.000
Chapter I Certain infectious and parasitic diseases
0.811 0.189 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.810 0.190 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.810 0.190 0.000
O61 Failed induction of labour
0.808 0.192 0.000
H02.4 Ptosis of eyelid
0.807 0.193 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.806 0.194 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.805 0.195 0.000
H05 Disorders of orbit
0.805 0.195 0.000
E21.3 Hyperparathyroidism, unspecified
0.798 0.202 0.000
T51 Toxic effect of alcohol
0.791 0.209 0.000
M48.02 Spinal stenosis (Cervical region)
0.791 0.209 0.000
S51.0 Open wound of elbow
0.789 0.211 0.000
O02 Other abnormal products of conception
0.789 0.211 0.000
I25.4 Coronary artery aneurysm
0.787 0.213 0.000
T87 Complications peculiar to reattachment and amputation
0.787 0.213 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.785 0.215 0.000
M05-M14 Inflammatory polyarthropathies
0.782 0.218 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.782 0.218 0.000
H02.9 Disorder of eyelid, unspecified
0.780 0.220 0.000
E22 Hyperfunction of pituitary gland
0.779 0.221 0.000
S56 Injury of muscle and tendon at forearm level
0.778 0.222 0.000
S72.0 Fracture of neck of femur
0.776 0.224 0.000
U88 Agent resistant to multiple antibiotics
0.776 0.224 0.000
H02.1 Ectropion of eyelid
0.774 0.226 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.773 0.226 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.772 0.228 0.000
B35-B49 Mycoses
0.770 0.230 0.000
S52.4 Fracture of shafts of both ulna and radius
0.770 0.230 0.000
H02.8 Other specified disorders of eyelid
0.768 0.232 0.000
U80.0 Penicillin resistant agent
0.768 0.232 0.000
E21.0 Primary hyperparathyroidism
0.768 0.232 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.768 0.232 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.767 0.233 0.000
Y84.0 Cardiac catheterisation
0.767 0.233 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.766 0.233 0.000
T90.5 Sequelae of intracranial injury
0.763 0.237 0.000
O04 Medical abortion
0.762 0.238 0.000
T39.0 Salicylates
0.762 0.238 0.000
S52.2 Fracture of shaft of ulna
0.761 0.239 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.760 0.240 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.759 0.241 0.000
O45 Premature separation of placenta [abruptio placentae]
0.758 0.242 0.000
S42.2 Fracture of upper end of humerus
0.757 0.242 0.000
I20.1 Angina pectoris with documented spasm
0.756 0.243 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.756 0.244 0.000
M45 Ankylosing spondylitis
0.756 0.244 0.000
S90-S99 Injuries to the ankle and foot
0.754 0.246 0.000
M91-M94 Chondropathies
0.754 0.246 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.753 0.247 0.000
T90.8 Sequelae of other specified injuries of head
0.753 0.247 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.752 0.248 0.000
O71 Other obstetric trauma
0.752 0.248 0.000
T93 Sequelae of injuries of lower limb
0.751 0.249 0.000
I95 Hypotension
0.751 0.249 0.000
S86 Injury of muscle and tendon at lower leg level
0.750 0.250 0.000
S52.6 Fracture of lower end of both ulna and radius
0.750 0.250 0.000
S80 Superficial injury of lower leg
0.750 0.250 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.749 0.251 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.748 0.252 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.748 0.252 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.747 0.253 0.000
E10.5 With peripheral circulatory complications
0.747 0.253 0.000
Y00-Y09 Assault
0.746 0.254 0.000
S51.9 Open wound of forearm, part unspecified
0.746 0.254 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.745 0.255 0.000
W22 Striking against or struck by other objects
0.744 0.256 0.000
O85-O92 Complications predominantly related to the puerperium
0.743 0.257 0.000
X10-X19 Contact with heat and hot substances
0.743 0.257 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.742 0.258 0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes
0.742 0.258 0.000
E50-E64 Other nutritional deficiencies
0.742 0.258 0.000
T81 Complications of procedures, not elsewhere classified
0.742 0.258 0.000
S72.4 Fracture of lower end of femur
0.741 0.258 0.000
M48.04 Spinal stenosis (Thoracic region)
0.741 0.259 0.000
S81 Open wound of lower leg
0.741 0.259 0.000
I60-I69 Cerebrovascular diseases
0.739 0.261 0.000
E10.1 With ketoacidosis
0.739 0.261 0.000
H49 Paralytic strabismus
0.739 0.261 0.000
T86 Failure and rejection of transplanted organs and tissues
0.737 0.263 0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
0.737 0.263 0.000
S79 Other and unspecified injuries of hip and thigh
0.736 0.264 0.000
T82.3 Mechanical complication of other vascular grafts
0.736 0.264 0.000
B37 Candidiasis
0.735 0.265 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.733 0.267 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.732 0.268 0.000
O66 Other obstructed labour
0.731 0.269 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.731 0.269 0.000
O36.8 Maternal care for other specified foetal problems
0.730 0.270 0.000
I95.9 Hypotension, unspecified
0.729 0.271 0.000
X50-X57 Overexertion, travel and privation
0.729 0.271 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.727 0.273 0.000
U89 Agent resistant to other and unspecified antibiotics
0.727 0.273 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.727 0.273 0.000
H34.1 Central retinal artery occlusion
0.727 0.273 0.000
O00 Ectopic pregnancy
0.727 0.273 0.000
O62 Abnormalities of forces of labour
0.726 0.274 0.000
S52.01 Fracture of upper end of ulna (open)
0.726 0.274 0.000
H31 Other disorders of choroid
0.726 0.274 0.000
O75.8 Other specified complications of labour and delivery
0.725 0.275 0.000
O75.2 Pyrexia during labour, not elsewhere classified
0.722 0.278 0.000
V20-V29 Motorcycle rider injured in transport accident
0.722 0.278 0.000
I22.8 Subsequent myocardial infarction of other sites
0.720 0.280 0.000
T92.1 Sequelae of fracture of arm
0.719 0.281 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.719 0.281 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
X20-X29 Contact with venomous animals and plants
0.717 0.283 0.000
S59 Other and unspecified injuries of forearm
0.716 0.283 0.000
S58 Traumatic amputation of forearm
0.716 0.283 0.000
S57 Crushing injury of forearm
0.716 0.283 0.000
S55 Injury of blood vessels at forearm level
0.716 0.283 0.000
S54 Injury of nerves at forearm level
0.716 0.283 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.716 0.283 0.000
S72.1 Pertrochanteric fracture
0.716 0.283 0.000
I25.6 Silent myocardial ischaemia
0.716 0.284 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.716 0.284 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.716 0.284 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.716 0.284 0.000
S52.9 Fracture of forearm, part unspecified
0.715 0.285 0.000
S52.7 Multiple fractures of forearm
0.715 0.285 0.000
S52.3 Fracture of shaft of radius
0.715 0.285 0.000
I00-I02 Acute rheumatic fever
0.715 0.285 0.000
T90.9 Sequelae of unspecified injury of head
0.715 0.285 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.715 0.285 0.000
O74 Complications of anaesthesia during labour and delivery
0.714 0.285 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.714 0.285 0.000
O60 Preterm delivery
0.714 0.285 0.000
H34.8 Other retinal vascular occlusions
0.714 0.286 0.000
M80-M85 Disorders of bone density and structure
0.714 0.286 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.714 0.286 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.713 0.287 0.000
S52.51 Fracture of lower end of radius (open)
0.712 0.287 0.000
H10-H13 Disorders of conjunctiva
0.712 0.288 0.000
O63.2 Delayed delivery of second twin, triplet, etc.
0.711 0.289 0.000
M70-M79 Other soft tissue disorders
0.711 0.289 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.711 0.289 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.711 0.289 0.000
Y35-Y36 Legal intervention and operations of war
0.711 0.289 0.000
Y10-Y34 Event of undetermined intent
0.711 0.289 0.000
X85-X99 Assault
0.711 0.289 0.000
X30-X39 Exposure to forces of nature
0.711 0.289 0.000
X00-X09 Exposure to smoke, fire and flames
0.711 0.289 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.711 0.289 0.000
W75-W84 Other accidental threats to breathing
0.711 0.289 0.000
W65-W74 Accidental drowning and submersion
0.711 0.289 0.000
W50-W64 Exposure to animate mechanical forces
0.711 0.289 0.000
V98-V99 Other and unspecified transport accidents
0.711 0.289 0.000
V95-V97 Air and space transport accidents
0.711 0.289 0.000
V90-V94 Water transport accidents
0.711 0.289 0.000
V70-V79 Bus occupant injured in transport accident
0.711 0.289 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.711 0.289 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.711 0.289 0.000
V40-V49 Car occupant injured in transport accident
0.711 0.289 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.711 0.289 0.000
V01-V09 Pedestrian injured in transport accident
0.711 0.289 0.000
S51.8 Open wound of other parts of forearm
0.710 0.289 0.000
O02.1 Missed abortion
0.709 0.291 0.000
M50.2 Other cervical disk displacement
0.708 0.292 0.000
X60-X84 Intentional self-harm
0.708 0.292 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.707 0.293 0.000
H43-H45 Disorders of vitreous body and globe
0.706 0.293 0.000
S42.20 Fracture of upper end of humerus (closed)
0.706 0.293 0.000
B37.0 Candidal stomatitis
0.706 0.294 0.000
O43 Placental disorders
0.706 0.294 0.000
I25.5 Ischaemic cardiomyopathy
0.704 0.295 0.000
T95 Sequelae of burns, corrosions and frostbite
0.704 0.295 0.000
T91 Sequelae of injuries of neck and trunk
0.704 0.295 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.704 0.295 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.704 0.295 0.000
M40-M43 Deforming dorsopathies
0.703 0.297 0.000
T59 Toxic effect of other gases, fumes and vapours
0.703 0.297 0.000
O75.7 Vaginal delivery following previous Caesarean section
0.703 0.297 0.000
O44 Placenta praevia
0.702 0.298 0.000
O33 Maternal care for known or suspected disproportion
0.702 0.298 0.000
O31 Complications specific to multiple gestation
0.702 0.298 0.000
E10.4 With neurological complications
0.701 0.299 0.000
S82 Fracture of lower leg, including ankle
0.701 0.299 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.700 0.299 0.000
H30 Chorioretinal inflammation
0.700 0.299 0.000
S41 Open wound of shoulder and upper arm
0.700 0.300 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.700 0.300 0.000
S52.8 Fracture of other parts of forearm
0.699 0.301 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.699 0.301 0.000
H55-H59 Other disorders of eye and adnexa
0.699 0.301 0.000
M50.0 Cervical disk disorder with myelopathy
0.698 0.302 0.000
O40 Polyhydramnios
0.698 0.302 0.000
S72.00 Fracture of neck of femur (closed)
0.697 0.303 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.696 0.304 0.000
S72.2 Subtrochanteric fracture
0.694 0.306 0.000
Y84.1 Kidney dialysis
0.694 0.306 0.000
H02.7 Other degenerative disorders of eyelid and periocular area
0.693 0.307 0.000
H02.2 Lagophthalmos
0.693 0.307 0.000
T98 Sequelae of other and unspecified effects of external causes
0.693 0.307 0.000
O36.5 Maternal care for poor foetal growth
0.692 0.308 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.691 0.309 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.691 0.309 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.691 0.309 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.691 0.309 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.691 0.309 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.691 0.309 0.000
T36 Poisoning by systemic antibiotics
0.691 0.309 0.000
E11 Non-insulin-dependent diabetes mellitus
0.691 0.309 0.000
E20 Hypoparathyroidism
0.690 0.310 0.000
O41 Other disorders of amniotic fluid and membranes
0.689 0.311 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.688 0.312 0.000
H02.6 Xanthelasma of eyelid
0.687 0.313 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.687 0.313 0.000
M89 Other disorders of bone
0.687 0.313 0.000
T51.0 Ethanol
0.686 0.314 0.000
O42 Premature rupture of membranes
0.686 0.314 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.686 0.314 0.000
H06.2 Dysthyroid exophthalmos
0.684 0.316 0.000
O73 Retained placenta and membranes, without haemorrhage
0.684 0.316 0.000
E27 Other disorders of adrenal gland
0.684 0.316 0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
0.683 0.316 0.000
O36.6 Maternal care for excessive foetal growth
0.683 0.317 0.000
M48.09 Spinal stenosis (Site unspecified)
0.683 0.317 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.683 0.317 0.000
O97 Death from sequelae of direct obstetric causes
0.683 0.317 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.683 0.317 0.000
O95 Obstetric death of unspecified cause
0.683 0.317 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.683 0.317 0.000
T90.3 Sequelae of injury of cranial nerves
0.683 0.317 0.000
T90.1 Sequelae of open wound of head
0.683 0.317 0.000
T90.0 Sequelae of superficial injury of head
0.683 0.317 0.000
Y89 Sequelae of other external causes
0.682 0.318 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.682 0.318 0.000
M86 Osteomyelitis
0.681 0.318 0.000
W25 Contact with sharp glass
0.681 0.319 0.000
M49 Spondylopathies in diseases classified elsewhere
0.680 0.320 0.000
S42.0 Fracture of clavicle
0.679 0.321 0.000
H05.0 Acute inflammation of orbit
0.678 0.322 0.000
Y48 Anaesthetics and therapeutic gases
0.678 0.322 0.000
V80-V89 Other land transport accidents
0.677 0.323 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.677 0.323 0.000
M06 Other rheumatoid arthritis
0.677 0.323 0.000
O75.0 Maternal distress during labour and delivery
0.676 0.324 0.000
H01 Other inflammation of eyelid
0.676 0.324 0.000
S78 Traumatic amputation of hip and thigh
0.675 0.325 0.000
S77 Crushing injury of hip and thigh
0.675 0.325 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.675 0.325 0.000
S75 Injury of blood vessels at hip and thigh level
0.675 0.325 0.000
S74 Injury of nerves at hip and thigh level
0.675 0.325 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.675 0.325 0.000
S71 Open wound of hip and thigh
0.675 0.325 0.000
M53 Other dorsopathies, not elsewhere classified
0.674 0.326 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.674 0.326 0.000
S50 Superficial injury of forearm
0.674 0.326 0.000
O61.0 Failed medical induction of labour
0.673 0.327 0.000
M51 Other intervertebral disk disorders
0.673 0.327 0.000
S70 Superficial injury of hip and thigh
0.673 0.327 0.000
W22.9 Unspecified place
0.671 0.329 0.000
M00-M03 Infectious arthropathies
0.670 0.330 0.000
H33.4 Traction detachment of retina
0.670 0.330 0.000
H33.1 Retinoschisis and retinal cysts
0.670 0.330 0.000
I61 Intracerebral haemorrhage
0.669 0.331 0.000
H33.5 Other retinal detachments
0.666 0.334 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.666 0.334 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.666 0.334 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.666 0.334 0.000
T39.4 Antirheumatics, not elsewhere classified
0.666 0.334 0.000
T39.2 Pyrazolone derivatives
0.666 0.334 0.000
E26 Hyperaldosteronism
0.666 0.334 0.000
U81 Agent resistant to vancomycin and related antibiotics
0.666 0.334 0.000
U50 Level of care administered to neonates
0.666 0.334 0.000
U07 Emergency use of U07
0.666 0.334 0.000
U06 Emergency use of U06
0.666 0.334 0.000
U04 Severe acute respiratory syndrome [SARS]
0.666 0.334 0.000
U52 First in a series of a regular day/night admissions
0.666 0.334 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.665 0.335 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.665 0.335 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.665 0.335 0.000
U80.8 Agent resistant to other penicillin-related antibiotic
0.665 0.335 0.000
M48.9 Spondylopathy, unspecified
0.664 0.336 0.000
M48.8 Other specified spondylopathies
0.664 0.336 0.000
M48.4 Fatigue fracture of vertebra
0.664 0.336 0.000
M48.3 Traumatic spondylopathy
0.664 0.336 0.000
M48.2 Kissing spine
0.664 0.336 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.664 0.336 0.000
E13 Other specified diabetes mellitus
0.662 0.338 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.661 0.338 0.000
M88 Paget's disease of bone [osteitis deformans]
0.660 0.340 0.000
O35.8 Maternal care for other (suspected) foetal abnormality and damage
0.659 0.341 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.659 0.341 0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium
0.658 0.341 0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium
0.658 0.341 0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
0.658 0.341 0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
0.658 0.341 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.658 0.342 0.000
E34 Other endocrine disorders
0.658 0.342 0.000
E32 Diseases of thymus
0.658 0.342 0.000
E31 Polyglandular dysfunction
0.658 0.342 0.000
E30 Disorders of puberty, not elsewhere classified
0.658 0.342 0.000
E25 Adrenogenital disorders
0.658 0.342 0.000
E24 Cushing's syndrome
0.658 0.342 0.000
Y52 Agents primarily affecting the cardiovascular system
0.658 0.342 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.658 0.342 0.000
H34.9 Retinal vascular occlusion, unspecified
0.657 0.343 0.000
H34.0 Transient retinal artery occlusion
0.657 0.343 0.000
E10.2 With renal complications
0.657 0.343 0.000
S10 Superficial injury of neck
0.656 0.344 0.000
E12 Malnutrition-related diabetes mellitus
0.655 0.345 0.000
S51.7 Multiple open wounds of forearm
0.654 0.346 0.000
B65-B83 Helminthiases
0.654 0.346 0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)
0.654 0.346 0.000
M48.05 Spinal stenosis (Thoracolumbar region)
0.654 0.346 0.000
M48.03 Spinal stenosis (Cervicothoracic region)
0.654 0.346 0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)
0.654 0.346 0.000
T79-T79 Certain early complications of trauma
0.653 0.347 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.653 0.347 0.000
E55 Vitamin D deficiency
0.653 0.347 0.000
O75.9 Complication of labour and delivery, unspecified
0.652 0.348 0.000
O75.5 Delayed delivery after artificial rupture of membranes
0.652 0.348 0.000
O75.4 Other complications of obstetric surgery and procedures
0.652 0.348 0.000
O75.3 Other infection during labour
0.652 0.348 0.000
O75.1 Shock during or following labour and delivery
0.652 0.348 0.000
H50 Other strabismus
0.652 0.348 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.651 0.349 0.000
M60 Myositis
0.651 0.349 0.000
E10.3 With ophthalmic complications
0.650 0.350 0.000
M62 Other disorders of muscle
0.649 0.351 0.000
S88 Traumatic amputation of lower leg
0.648 0.352 0.000
S87 Crushing injury of lower leg
0.648 0.352 0.000
S85 Injury of blood vessels at lower leg level
0.648 0.352 0.000
S84 Injury of nerves at lower leg level
0.648 0.352 0.000
Y88 Sequelae of surgical and medical care as external cause
0.647 0.353 0.000
I78 Diseases of capillaries
0.647 0.353 0.000
M46 Other inflammatory spondylopathies
0.646 0.354 0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
0.645 0.355 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.645 0.355 0.000
O07 Failed attempted abortion
0.645 0.355 0.000
O06 Unspecified abortion
0.645 0.355 0.000
O05 Other abortion
0.645 0.355 0.000
O01 Hydatidiform mole
0.645 0.355 0.000
U51 Admission status on psychiatric patients
0.642 0.358 0.000
H00 Hordeolum and chalazion
0.642 0.358 0.000
M90 Osteopathies in diseases classified elsewhere
0.641 0.359 0.000
Y84.6 Urinary catheterisation
0.641 0.359 0.000
T65 Toxic effect of other and unspecified substances
0.640 0.360 0.000
T62 Toxic effect of other noxious substances eaten as food
0.640 0.360 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.640 0.360 0.000
T60 Toxic effect of pesticides
0.640 0.360 0.000
T57 Toxic effect of other inorganic substances
0.640 0.360 0.000
T56 Toxic effect of metals
0.640 0.360 0.000
T54 Toxic effect of corrosive substances
0.640 0.360 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.640 0.360 0.000
T52 Toxic effect of organic solvents
0.640 0.360 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.640 0.360 0.000
T58 Toxic effect of carbon monoxide
0.640 0.360 0.000
T55 Toxic effect of soaps and detergents
0.640 0.360 0.000
T63 Toxic effect of contact with venomous animals
0.640 0.360 0.000
E29 Testicular dysfunction
0.640 0.360 0.000
E10.8 With unspecified complications
0.640 0.360 0.000
E10.7 With multiple complications
0.640 0.360 0.000
E10.6 With other specified complications
0.640 0.360 0.000
E10.0 With coma
0.640 0.360 0.000
B15-B19 Viral hepatitis
0.640 0.360 0.000
E40-E46 Malnutrition
0.639 0.361 0.000
S48 Traumatic amputation of shoulder and upper arm
0.639 0.361 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.639 0.361 0.000
S44 Injury of nerves at shoulder and upper arm level
0.639 0.361 0.000
S47 Crushing injury of shoulder and upper arm
0.639 0.361 0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus
0.639 0.361 0.000
M50.9 Cervical disk disorder, unspecified
0.639 0.361 0.000
M50.8 Other cervical disk disorders
0.639 0.361 0.000
T87.6 Other and unspecified complications of amputation stump
0.639 0.361 0.000
H36 Retinal disorders in diseases classified elsewhere
0.638 0.362 0.000
H35 Other retinal disorders
0.638 0.362 0.000
O69.1 Labour and delivery complicated by cord around neck, with compression
0.637 0.363 0.000
S72.40 Fracture of lower end of femur (closed)
0.637 0.363 0.000
S89 Other and unspecified injuries of lower leg
0.637 0.363 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.637 0.363 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.636 0.363 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.636 0.363 0.000
S72.9 Fracture of femur, part unspecified
0.636 0.364 0.000
S72.8 Fractures of other parts of femur
0.636 0.364 0.000
S72.7 Multiple fractures of femur
0.636 0.364 0.000
O30 Multiple gestation
0.635 0.364 0.000
T51.9 Alcohol, unspecified
0.636 0.364 0.000
Y59 Other and unspecified vaccines and biological substances
0.635 0.365 0.000
Y58 Bacterial vaccines
0.635 0.365 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.635 0.365 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.635 0.365 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.635 0.365 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.635 0.365 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.635 0.365 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.635 0.365 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.635 0.365 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.634 0.366 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.634 0.366 0.000
U84 Resistance to other antimicrobial drugs
0.633 0.367 0.000
U83 Resistance to other antibiotics
0.633 0.367 0.000
U82 Resistance to betalactam antibiotics
0.633 0.367 0.000
U85 Resistance to antineoplastic drugs
0.633 0.367 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.633 0.367 0.000
E21.4 Other specified disorders of parathyroid gland
0.633 0.367 0.000
E21.2 Other hyperparathyroidism
0.633 0.367 0.000
H49.1 Fourth [trochlear] nerve palsy
0.633 0.367 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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