TreeWAS – Variant ID: rs116155186

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.997	0.003
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.995	0.005
E70-E90 Metabolic disorders	0.976	0.024
Chapter XII Diseases of the skin and subcutaneous tissue	0.976	0.024
E65-E68 Obesity and other hyperalimentation	0.968	0.032
Chapter IX Diseases of the circulatory system	0.961	0.039
L00-L08 Infections of the skin and subcutaneous tissue	0.955	0.045
Chapter XIV Diseases of the genitourinary system	0.950	0.050
Chapter II Neoplasms	0.948	0.052
L03 Cellulitis	0.947	0.053
E66 Obesity	0.947	0.053
Chapter XV Pregnancy, childbirth and the puerperium	0.945	0.055
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.937	0.063
L03.1 Cellulitis of other parts of limb	0.933	0.067
E66.9 Obesity, unspecified	0.932	0.068
I30-I52 Other forms of heart disease	0.931	0.069
M20-M25 Other joint disorders	0.925	0.075
E87 Other disorders of fluid, electrolyte and acid-base balance	0.918	0.082
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.915	0.085
Chapter XXI Factors influencing health status and contact with health services	0.914	0.086
I70-I79 Diseases of arteries, arterioles and capillaries	0.906	0.094
M45-M49 Spondylopathies	0.901	0.099
Z40-Z54 Persons encountering health services for specific procedures and health care	0.894	0.106
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.890	0.110
Chapter VIII Diseases of the ear and mastoid process	0.882	0.118
Z53 Persons encountering health services for specifie procedures, not carried out	0.870	0.130
E87.5 Hyperkalaemia	0.868	0.132
M50-M54 Other dorsopathies	0.866	0.134
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.863	0.137
Chapter XX External causes of morbidity and mortality	0.860	0.140
M25 Other joint disorders, not elsewhere classified	0.860	0.140
M15-M19 Arthrosis	0.859	0.141
E10-E14 Diabetes mellitus	0.847	0.153
O20-O29 Other maternal disorders predominantly related to pregnancy	0.840	0.160
E86 Volume depletion	0.837	0.163
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.834	0.166
I05-I09 Chronic rheumatic heart diseases	0.831	0.169
I42 Cardiomyopathy	0.820	0.180
N80-N98 Noninflammatory disorders of female genital tract	0.820	0.180
C77.3 Axillary and upper limb lymph nodes	0.816	0.184
N25-N29 Other disorders of kidney and ureter	0.815	0.185
N60-N64 Disorders of breast	0.815	0.185
D50-D53 Nutritional anaemias	0.812	0.188
Z53.0 Procedure not carried out because of contraindication	0.802	0.198
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.802	0.198
Z53.8 Procedure not carried out for other reasons	0.797	0.203
O60-O75 Complications of labour and delivery	0.795	0.205
M47 Spondylosis	0.793	0.207
L80-L99 Other disorders of the skin and subcutaneous tissue	0.793	0.207
D37-D48 Neoplasms of uncertain or unknown behaviour	0.791	0.209
M80-M85 Disorders of bone density and structure	0.790	0.210
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.790	0.210
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.789	0.211
I74 Arterial embolism and thrombosis	0.788	0.212
L03.2 Cellulitis of face	0.786	0.214
N84 Polyp of female genital tract	0.785	0.215
Chapter VI Diseases of the nervous system	0.782	0.218
Chapter I Certain infectious and parasitic diseases	0.781	0.219
E87.1 Hypo-osmolality and hyponatraemia	0.781	0.219
N70-N77 Inflammatory diseases of female pelvic organs	0.780	0.220
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.780	0.220
M17 Gonarthrosis [arthrosis of knee]	0.780	0.220
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.776	0.223
N17-N19 Renal failure	0.775	0.225
I51 Complications and ill-defined descriptions of heart disease	0.775	0.225
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.771	0.229
O00-O08 Pregnancy with abortive outcome	0.771	0.229
I44 Atrioventricular and left bundle-branch block	0.768	0.232
Z50 Care involving use of rehabilitation procedures	0.767	0.233
D00-D09 In situ neoplasms	0.759	0.241
I50 Heart failure	0.757	0.243
M05-M14 Inflammatory polyarthropathies	0.756	0.244
Z47 Other orthopaedic follow-up care	0.754	0.246
E80 Disorders of porphyrin and bilirubin metabolism	0.751	0.249
N84.0 Polyp of corpus uteri	0.750	0.250
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.749	0.251
I77 Other disorders of arteries and arterioles	0.749	0.251
M23 Internal derangement of knee	0.746	0.254
L03.9 Cellulitis, unspecified	0.743	0.257
M25.5 Pain in joint	0.743	0.257
Z53.9 Procedure not carried out, unspecified reason	0.741	0.259
C77.4 Inguinal and lower limb lymph nodes	0.740	0.260
Z52 Donors of organs and tissues	0.740	0.260
D60-D64 Aplastic and other anaemias	0.740	0.260
I73 Other peripheral vascular diseases	0.739	0.261
I08 Multiple valve diseases	0.738	0.262
Y83.1 Surgical operation with implant of artificial internal device	0.738	0.262
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.737	0.263
N10-N16 Renal tubulo-interstitial diseases	0.737	0.263
D10-D36 Benign neoplasms	0.737	0.263
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.736	0.264
N00-N08 Glomerular diseases	0.735	0.265
M22 Disorders of patella	0.734	0.266
I34 Nonrheumatic mitral valve disorders	0.733	0.267
I49 Other cardiac arrhythmias	0.732	0.268
M65-M68 Disorders of synovium and tendon	0.731	0.269
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.729	0.271
L50-L54 Urticaria and erythema	0.728	0.272
Z33 Pregnant state, incidental	0.728	0.272
C51-C58 Malignant neoplasms of female genital organs	0.727	0.273
D70-D77 Other diseases of blood and blood-forming organs	0.726	0.274
D80-D89 Certain disorders involving the immune mechanism	0.725	0.275
H90-H95 Other disorders of ear	0.724	0.276
L60-L75 Disorders of skin appendages	0.723	0.277
M17.1 Other primary gonarthrosis	0.723	0.277
C77.0 Lymph nodes of head, face and neck	0.721	0.279
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.721	0.279
H65-H75 Diseases of middle ear and mastoid	0.720	0.280
M25.4 Effusion of joint	0.720	0.280
L03.3 Cellulitis of trunk	0.719	0.281
N28 Other disorders of kidney and ureter, not elsewhere classified	0.719	0.281
M48 Other spondylopathies	0.719	0.281
R19 Other symptoms and signs involving the digestive system and abdomen	0.718	0.282
M54 Dorsalgia	0.717	0.283
Chapter XXII Codes for special purposes	0.717	0.283
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
E50-E64 Other nutritional deficiencies	0.715	0.285
E40-E46 Malnutrition	0.715	0.285
E20-E35 Disorders of other endocrine glands	0.715	0.285
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.713	0.287
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.713	0.287
M91-M94 Chondropathies	0.713	0.287
M86-M90 Other osteopathies	0.713	0.287
M60-M63 Disorders of muscles	0.713	0.287
M00-M03 Infectious arthropathies	0.713	0.287
O20 Haemorrhage in early pregnancy	0.710	0.290
I42.9 Cardiomyopathy, unspecified	0.706	0.294
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.702	0.298
O26 Maternal care for other conditions predominantly related to pregnancy	0.701	0.299
E10 Insulin-dependent diabetes mellitus	0.700	0.300
E88 Other metabolic disorders	0.700	0.300
E85 Amyloidosis	0.700	0.300
E84 Cystic fibrosis	0.700	0.300
E79 Disorders of purine and pyrimidine metabolism	0.700	0.300
E77 Disorders of glycoprotein metabolism	0.700	0.300
E76 Disorders of glycosaminoglycan metabolism	0.700	0.300
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.700	0.300
E74 Other disorders of carbohydrate metabolism	0.700	0.300
E73 Lactose intolerance	0.700	0.300
E72 Other disorders of amino-acid metabolism	0.700	0.300
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.700	0.300
E70 Disorders of aromatic amino-acid metabolism	0.700	0.300
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.700	0.300
L10-L14 Bullous disorders	0.700	0.300
Z50.9 Care involving use of rehabilitation procedure, unspecified	0.700	0.300
N93 Other abnormal uterine and vaginal bleeding	0.699	0.301
C77.1 Intrathoracic lymph nodes	0.699	0.301
I45 Other conduction disorders	0.698	0.302
M40-M43 Deforming dorsopathies	0.698	0.302
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.697	0.303
I70 Atherosclerosis	0.695	0.305
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.694	0.306
E67 Other hyperalimentation	0.694	0.306
E68 Sequelae of hyperalimentation	0.694	0.306
E65 Localised adiposity	0.694	0.306
L40-L45 Papulosquamous disorders	0.693	0.307
I95-I99 Other and unspecified disorders of the circulatory system	0.693	0.307
I31 Other diseases of pericardium	0.693	0.307
M24 Other specific joint derangements	0.692	0.308
M25.7 Osteophyte	0.691	0.309
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified	0.691	0.309
I00-I02 Acute rheumatic fever	0.689	0.311
I46 Cardiac arrest	0.688	0.312
L20-L30 Dermatitis and eczema	0.687	0.313
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.685	0.315
L05 Pilonidal cyst	0.684	0.316
L04 Acute lymphadenitis	0.684	0.316
L01 Impetigo	0.684	0.316
L00 Staphylococcal scalded skin syndrome	0.684	0.316
M31 Other necrotising vasculopathies	0.684	0.316
H60-H62 Diseases of external ear	0.682	0.318
Y83.2 Surgical operation with anastomosis, bypass or graft	0.682	0.318
M45 Ankylosing spondylitis	0.681	0.319
E66.8 Other obesity	0.681	0.319
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.679	0.320
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.679	0.320
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.679	0.320
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.679	0.320
C40-C41 Malignant neoplasms of bone and articular cartilage	0.679	0.320
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.679	0.320
R94 Abnormal results of function studies	0.679	0.321
L03.8 Cellulitis of other sites	0.679	0.321
E66.2 Extreme obesity with alveolar hypoventilation	0.679	0.321
E66.1 Drug-induced obesity	0.679	0.321
E66.0 Obesity due to excess calories	0.679	0.321
D25 Leiomyoma of uterus	0.679	0.321
C77.9 Lymph node, unspecified	0.678	0.322
O85-O92 Complications predominantly related to the puerperium	0.678	0.322
R19.8 Other specified symptoms and signs involving the digestive system and abdomen	0.677	0.323
R20 Disturbances of skin sensation	0.676	0.324
I78 Diseases of capillaries	0.676	0.324
M50 Cervical disk disorders	0.675	0.325
Z31 Procreative management	0.673	0.327
C79 Secondary malignant neoplasm of other sites	0.672	0.328
D55-D59 Haemolytic anaemias	0.672	0.328
E83 Disorders of mineral metabolism	0.672	0.328
O80-O84 Delivery	0.671	0.328
L03.0 Cellulitis of finger and toe	0.671	0.329
I73.9 Peripheral vascular disease, unspecified	0.671	0.329
M51 Other intervertebral disk disorders	0.671	0.329
D50 Iron deficiency anaemia	0.669	0.331
D51 Vitamin B12 deficiency anaemia	0.668	0.331
I52 Other heart disorders in diseases classified elsewhere	0.667	0.332
I48 Atrial fibrillation and flutter	0.667	0.332
I43 Cardiomyopathy in diseases classified elsewhere	0.667	0.332
I41 Myocarditis in diseases classified elsewhere	0.667	0.332
I40 Acute myocarditis	0.667	0.332
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.667	0.332
I37 Pulmonary valve disorders	0.667	0.332
I36 Nonrheumatic tricuspid valve disorders	0.667	0.332
I33 Acute and subacute endocarditis	0.667	0.332
I32 Pericarditis in diseases classified elsewhere	0.667	0.332
I30 Acute pericarditis	0.667	0.332
I38 Endocarditis, valve unspecified	0.667	0.332
N99-N99 Other disorders of the genitourinary system	0.667	0.333
O94-O99 Other obstetric conditions, not elsewhere classified	0.667	0.333
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.666	0.334
Z34 Supervision of normal pregnancy	0.664	0.336
M47.8 Other spondylosis	0.663	0.337
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.663	0.337
M34 Systemic sclerosis	0.663	0.337
M33 Dermatopolymyositis	0.663	0.337
M32 Systemic lupus erythematosus	0.663	0.337
M30 Polyarteritis nodosa and related conditions	0.663	0.337
M21 Other acquired deformities of limbs	0.663	0.337
Z39 Postpartum care and examination	0.663	0.337
O72 Postpartum haemorrhage	0.663	0.337
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.660	0.340
M47.9 Spondylosis, unspecified	0.659	0.341
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.658	0.342
E87.4 Mixed disorder of acid-base balance	0.658	0.342
E87.3 Alkalosis	0.658	0.342
E87.0 Hyperosmolality and hypernatraemia	0.658	0.342
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.657	0.343
E87.7 Fluid overload	0.657	0.343
I42.0 Dilated cardiomyopathy	0.656	0.343
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.656	0.344
N62 Hypertrophy of breast	0.656	0.344
C80 Malignant neoplasm without specification of site	0.656	0.344
C76 Malignant neoplasm of other and ill-defined sites	0.656	0.344
E89.0 Postprocedural hypothyroidism	0.656	0.344
I10-I15 Hypertensive diseases	0.656	0.344
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.655	0.345
M70-M79 Other soft tissue disorders	0.652	0.348
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.652	0.348
N85 Other noninflammatory disorders of uterus, except cervix	0.651	0.349
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.651	0.349
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.650	0.350
I72 Other aneurysm	0.650	0.350
O03 Spontaneous abortion	0.650	0.350
C60-C63 Malignant neoplasms of male genital organs	0.649	0.351
C77.2 Intra-abdominal lymph nodes	0.647	0.353
E11 Non-insulin-dependent diabetes mellitus	0.647	0.353
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.647	0.353
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.646	0.354
M49 Spondylopathies in diseases classified elsewhere	0.646	0.354
M46 Other inflammatory spondylopathies	0.646	0.354
M81 Osteoporosis without pathological fracture	0.643	0.357
N73 Other female pelvic inflammatory diseases	0.642	0.357
M13 Other arthritis	0.642	0.358
L97 Ulcer of lower limb, not elsewhere classified	0.641	0.359
Z54 Convalescence	0.641	0.359
Z49 Care involving dialysis	0.641	0.359
Z44 Fitting and adjustment of external prosthetic device	0.641	0.359
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.641	0.359
Z36 Antenatal screening	0.640	0.360
I50.0 Congestive heart failure	0.640	0.360
N80 Endometriosis	0.639	0.361
C77.8 Lymph nodes of multiple regions	0.638	0.362
C77.5 Intrapelvic lymph nodes	0.638	0.362
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.636	0.364
I77.1 Stricture of artery	0.636	0.364
E14 Unspecified diabetes mellitus	0.635	0.365
C15-C26 Malignant neoplasms of digestive organs	0.635	0.365
O75 Other complications of labour and delivery, not elsewhere classified	0.635	0.365
I47 Paroxysmal tachycardia	0.634	0.366
N17 Acute renal failure	0.634	0.366
L08 Other local infections of skin and subcutaneous tissue	0.633	0.367
R90 Abnormal findings on diagnostic imaging of central nervous system	0.633	0.367
N84.1 Polyp of cervix uteri	0.633	0.367
G50-G59 Nerve, nerve root and plexus disorders	0.633	0.367
M18 Arthrosis of first carpometacarpal joint	0.632	0.368
Y60-Y69 Misadventures to patients during surgical and medical care	0.631	0.369
Z43 Attention to artificial openings	0.631	0.369
R21 Rash and other nonspecific skin eruption	0.631	0.369
Z52.4 Kidney donor	0.630	0.370
M16 Coxarthrosis [arthrosis of hip]	0.627	0.373
B95-B98 Bacterial, viral and other infectious agents	0.627	0.373
D25.1 Intramural leiomyoma of uterus	0.627	0.373
I08.1 Disorders of both mitral and tricuspid valves	0.626	0.374
E87.2 Acidosis	0.626	0.374
I50.9 Heart failure, unspecified	0.626	0.374
N61 Inflammatory disorders of breast	0.626	0.374
R93 Abnormal findings on diagnostic imaging of other body structures	0.626	0.374
I51.8 Other ill-defined heart diseases	0.625	0.375
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure	0.624	0.376
M23.8 Other internal derangements of knee	0.624	0.376
N86 Erosion and ectropion of cervix uteri	0.623	0.377
N28.8 Other specified disorders of kidney and ureter	0.623	0.377
I71 Aortic aneurysm and dissection	0.622	0.377
Z35 Supervision of high-risk pregnancy	0.622	0.378
H80-H83 Diseases of inner ear	0.622	0.378
N93.9 Abnormal uterine and vaginal bleeding, unspecified	0.621	0.379
N13 Obstructive and reflux uropathy	0.621	0.379
M53 Other dorsopathies, not elsewhere classified	0.621	0.379
N63 Unspecified lump in breast	0.621	0.379
D50.8 Other iron deficiency anaemias	0.621	0.379
M25.46 Effusion of joint (Lower leg)	0.620	0.380
R95-R99 Ill-defined and unknown causes of mortality	0.619	0.381
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.619	0.381
Z45 Adjustment and management of implanted device	0.619	0.381
S60-S69 Injuries to the wrist and hand	0.618	0.382
Z47.8 Other specified orthopaedic follow-up care	0.617	0.383
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.617	0.383
Y35-Y36 Legal intervention and operations of war	0.617	0.383
Y10-Y34 Event of undetermined intent	0.617	0.383
Y00-Y09 Assault	0.617	0.383
X85-X99 Assault	0.617	0.383
X60-X84 Intentional self-harm	0.617	0.383
X58-X59 Accidental exposure to other and unspecified factors	0.617	0.383
X50-X57 Overexertion, travel and privation	0.617	0.383
X40-X49 Accidental poisoning by and exposure to noxious substances	0.617	0.383
X30-X39 Exposure to forces of nature	0.617	0.383
X20-X29 Contact with venomous animals and plants	0.617	0.383
X10-X19 Contact with heat and hot substances	0.617	0.383
X00-X09 Exposure to smoke, fire and flames	0.617	0.383
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.617	0.383
W75-W84 Other accidental threats to breathing	0.617	0.383
W65-W74 Accidental drowning and submersion	0.617	0.383
W50-W64 Exposure to animate mechanical forces	0.617	0.383
W20-W49 Exposure to inanimate mechanical forces	0.617	0.383
V98-V99 Other and unspecified transport accidents	0.617	0.383
V95-V97 Air and space transport accidents	0.617	0.383
V90-V94 Water transport accidents	0.617	0.383
V80-V89 Other land transport accidents	0.617	0.383
V70-V79 Bus occupant injured in transport accident	0.617	0.383
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.617	0.383
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.617	0.383
V40-V49 Car occupant injured in transport accident	0.617	0.383
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.617	0.383
V20-V29 Motorcycle rider injured in transport accident	0.617	0.383
V10-V19 Pedal cyclist injured in transport accident	0.617	0.383
V01-V09 Pedestrian injured in transport accident	0.617	0.383
M25.9 Joint disorder, unspecified	0.616	0.383
M25.8 Other specified joint disorders	0.616	0.383
M25.6 Stiffness of joint, not elsewhere classified	0.616	0.383
M25.3 Other instability of joint	0.616	0.383
M25.2 Flail joint	0.616	0.383
M25.1 Fistula of joint	0.616	0.383
M25.0 Haemarthrosis	0.616	0.383
M15 Polyarthrosis	0.616	0.384
N90 Other noninflammatory disorders of vulva and perineum	0.615	0.385
M35 Other systemic involvement of connective tissue	0.614	0.386
N20-N23 Urolithiasis	0.614	0.386
O68 Labour and delivery complicated by foetal stress [distress]	0.613	0.386
A30-A49 Other bacterial diseases	0.612	0.387
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.611	0.389
I44.1 Atrioventricular block, second degree	0.610	0.390
I51.7 Cardiomegaly	0.610	0.390
E13 Other specified diabetes mellitus	0.607	0.393
E12 Malnutrition-related diabetes mellitus	0.607	0.393
R94.5 Abnormal results of liver function studies	0.607	0.393
N97 Female infertility	0.604	0.396
L98.9 Disorder of skin and subcutaneous tissue, unspecified	0.604	0.396
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.603	0.397
Chapter VII Diseases of the eye and adnexa	0.603	0.397
R47-R49 Symptoms and signs involving speech and voice	0.603	0.397
O26.8 Other specified pregnancy-related conditions	0.602	0.398
O29 Complications of anaesthesia during pregnancy	0.602	0.398
O28 Abnormal findings on antenatal screening of mother	0.602	0.398
O24 Diabetes mellitus in pregnancy	0.602	0.398
O23 Infections of genito-urinary tract in pregnancy	0.602	0.398
O22 Venous complications in pregnancy	0.602	0.398
O21 Excessive vomiting in pregnancy	0.602	0.398
O25 Malnutrition in pregnancy	0.602	0.398
M25.55 Pain in joint (Pelvic region and thigh)	0.600	0.399
E78.9 Disorder of lipoprotein metabolism, unspecified	0.600	0.400
Z42 Follow-up care involving plastic surgery	0.599	0.401
Z41 Procedures for purposes other than remedying health state	0.599	0.401
N64 Other disorders of breast	0.599	0.401
Z38 Liveborn infants according to place of birth	0.598	0.402
Z32 Pregnancy examination and test	0.598	0.402
R11 Nausea and vomiting	0.598	0.402
M22.4 Chondromalacia patellae	0.597	0.403
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device	0.597	0.403
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.597	0.403
Y83.4 Other reconstructive surgery	0.597	0.403
N60 Benign mammary dysplasia	0.597	0.403
I09 Other rheumatic heart diseases	0.596	0.404
I07 Rheumatic tricuspid valve diseases	0.596	0.404
I06 Rheumatic aortic valve diseases	0.596	0.404
I05 Rheumatic mitral valve diseases	0.596	0.404
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.596	0.404
Z50.0 Cardiac rehabilitation	0.596	0.404
E10.9 Without complications	0.595	0.405
I34.0 Mitral (valve) insufficiency	0.594	0.405
M25.51 Pain in joint (Shoulder region)	0.594	0.406
Z40 Prophylactic surgery	0.594	0.406
D69 Purpura and other haemorrhagic conditions	0.593	0.406
I44.2 Atrioventricular block, complete	0.593	0.407
G35-G37 Demyelinating diseases of the central nervous system	0.593	0.407
I49.0 Ventricular fibrillation and flutter	0.592	0.408
R19.4 Change in bowel habit	0.592	0.408
H71 Cholesteatoma of middle ear	0.592	0.408
C64-C68 Malignant neoplasms of urinary tract	0.591	0.409
R19.0 Intra-abdominal and pelvic swelling, mass and lump	0.591	0.409
D24 Benign neoplasm of breast	0.591	0.409
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.590	0.410
E80.4 Gilbert's syndrome	0.590	0.410
Z51 Other medical care	0.590	0.410
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.589	0.411
D05 Carcinoma in situ of breast	0.588	0.412
M54.3 Sciatica	0.588	0.412
M48.0 Spinal stenosis	0.588	0.412
D06 Carcinoma in situ of cervix uteri	0.588	0.412
I42.8 Other cardiomyopathies	0.588	0.412
I42.7 Cardiomyopathy due to drugs and other external agents	0.588	0.412
I42.6 Alcoholic cardiomyopathy	0.588	0.412
I42.5 Other restrictive cardiomyopathy	0.588	0.412
I42.4 Endocardial fibroelastosis	0.588	0.412
I42.3 Endomyocardial (eosinophilic) disease	0.588	0.412
I42.2 Other hypertrophic cardiomyopathy	0.588	0.412
I42.1 Obstructive hypertrophic cardiomyopathy	0.588	0.412
N98 Complications associated with artificial fertilisation	0.588	0.412
N91 Absent, scanty and rare menstruation	0.588	0.412
N82 Fistulae involving female genital tract	0.588	0.412
N96 Habitual aborter	0.588	0.412
Z70-Z76 Persons encountering health services in other circumstances	0.586	0.414
E78.0 Pure hypercholesterolaemia	0.586	0.414
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.586	0.414
G20-G26 Extrapyramidal and movement disorders	0.586	0.414
Z50.8 Care involving use of rehabilitation procedures	0.585	0.414
O42 Premature rupture of membranes	0.585	0.415
N29 Other disorders of kidney and ureter in diseases classified elsewhere	0.585	0.415
N27 Small kidney of unknown cause	0.585	0.415
N25 Disorders resulting from impaired renal tubular function	0.585	0.415
N26 Unspecified contracted kidney	0.585	0.415
C43-C44 Melanoma and other malignant neoplasms of skin	0.584	0.415
M47.96 Spondylosis, unspecified (Lumbar region)	0.585	0.415
N72 Inflammatory disease of cervix uteri	0.584	0.416
M25.75 Osteophyte (Pelvic region and thigh)	0.584	0.416
O20.9 Haemorrhage in early pregnancy, unspecified	0.584	0.416
Z48 Other surgical follow-up care	0.582	0.417
N87 Dysplasia of cervix uteri	0.582	0.417
D53 Other nutritional anaemias	0.582	0.418
D52 Folate deficiency anaemia	0.582	0.418
Z60 Problems related to social environment	0.582	0.418
A00-A09 Intestinal infectious diseases	0.582	0.418
R26 Abnormalities of gait and mobility	0.581	0.418
R12 Heartburn	0.580	0.420
M25.53 Pain in joint (Forearm)	0.579	0.421
R20.2 Paraesthesia of skin	0.579	0.421
N19 Unspecified renal failure	0.579	0.421
I44.7 Left bundle-branch block, unspecified	0.577	0.423
L71 Rosacea	0.577	0.423
G90-G99 Other disorders of the nervous system	0.575	0.424
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.575	0.425
N85.0 Endometrial glandular hyperplasia	0.575	0.425
H90 Conductive and sensorineural hearing loss	0.574	0.426
D61 Other aplastic anaemias	0.573	0.427
D86 Sarcoidosis	0.572	0.428
N28.1 Cyst of kidney, acquired	0.572	0.428
M17.0 Primary gonarthrosis, bilateral	0.572	0.428
M05 Seropositive rheumatoid arthritis	0.572	0.428
D25.0 Submucous leiomyoma of uterus	0.572	0.428
M54.5 Low back pain	0.572	0.428
S80-S89 Injuries to the knee and lower leg	0.571	0.428
M23.2 Derangement of meniscus due to old tear or injury	0.571	0.429
L90 Atrophic disorders of skin	0.571	0.429
O02 Other abnormal products of conception	0.571	0.429
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.571	0.429
I99 Other and unspecified disorders of circulatory system	0.571	0.429
D11 Benign neoplasm of major salivary glands	0.571	0.429
O74 Complications of anaesthesia during labour and delivery	0.570	0.430
O73 Retained placenta and membranes, without haemorrhage	0.570	0.430
O71 Other obstetric trauma	0.570	0.430
O69 Labour and delivery complicated by umbilical cord complications	0.570	0.430
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.570	0.430
O66 Other obstructed labour	0.570	0.430
O65 Obstructed labour due to maternal pelvic abnormality	0.570	0.430
O64 Obstructed labour due to malposition and malpresentation of foetus	0.570	0.430
O62 Abnormalities of forces of labour	0.570	0.430
O61 Failed induction of labour	0.570	0.430
O60 Preterm delivery	0.570	0.430
O70 Perineal laceration during delivery	0.570	0.430
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.570	0.430
M47.2 Other spondylosis with radiculopathy	0.568	0.431
M47.1 Other spondylosis with myelopathy	0.568	0.431
M47.0 Anterior spinal and vertebral artery compression syndromes	0.568	0.431
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.568	0.432
L95 Vasculitis limited to skin, not elsewhere classified	0.568	0.432
L94 Other localised connective tissue disorders	0.568	0.432
L93 Lupus erythematosus	0.568	0.432
L92 Granulomatous disorders of skin and subcutaneous tissue	0.568	0.432
L89 Decubitus ulcer	0.568	0.432
L87 Transepidermal elimination disorders	0.568	0.432
L85 Other epidermal thickening	0.568	0.432
L81 Other disorders of pigmentation	0.568	0.432

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations