TreeWAS – Variant ID: rs116226697

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
S60-S69 Injuries to the wrist and hand	1.000	0.000	0.000
S61 Open wound of wrist and hand	0.998	0.002	0.000
Chapter XIV Diseases of the genitourinary system	0.998	0.002	0.000
N20-N23 Urolithiasis	0.998	0.002	0.000
S61.0 Open wound of finger(s) without damage to nail	0.995	0.005	0.000
Chapter V Mental and behavioural disorders	0.995	0.005	0.000
N20 Calculus of kidney and ureter	0.995	0.005	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.994	0.006	0.000
E70-E90 Metabolic disorders	0.991	0.009	0.000
E83 Disorders of mineral metabolism	0.989	0.011	0.000
E83.1 Disorders of iron metabolism	0.988	0.012	0.000
Chapter VI Diseases of the nervous system	0.988	0.012	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.982	0.018	0.000
N17-N19 Renal failure	0.979	0.021	0.000
Chapter XX External causes of morbidity and mortality	0.979	0.021	0.000
Chapter IX Diseases of the circulatory system	0.975	0.025	0.000
J45.9 Asthma, unspecified	0.000	0.027	0.973
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.971	0.029	0.000
N23 Unspecified renal colic	0.965	0.035	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.962	0.038	0.000
N20.1 Calculus of ureter	0.960	0.040	0.000
I30-I52 Other forms of heart disease	0.960	0.040	0.000
I35 Nonrheumatic aortic valve disorders	0.954	0.046	0.000
N19 Unspecified renal failure	0.952	0.048	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.950	0.050	0.000
N20.0 Calculus of kidney	0.948	0.052	0.000
S61.8 Open wound of other parts of wrist and hand	0.947	0.053	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.939	0.061	0.000
E20-E35 Disorders of other endocrine glands	0.937	0.063	0.000
S00-S09 Injuries to the head	0.932	0.068	0.000
T66-T78 Other and unspecified effects of external causes	0.923	0.077	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.921	0.079	0.000
I35.0 Aortic (valve) stenosis	0.920	0.080	0.000
G40-G47 Episodic and paroxysmal disorders	0.920	0.080	0.000
F30-F39 Mood [affective] disorders	0.919	0.081	0.000
Chapter XXI Factors influencing health status and contact with health services	0.910	0.090	0.000
I71 Aortic aneurysm and dissection	0.910	0.090	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.907	0.093	0.000
Z00-Z13 Persons encountering health services for examination and investigation	0.902	0.098	0.000
Z13 Special screening examination for other diseases and disorders	0.899	0.101	0.000
N20.2 Calculus of kidney with calculus of ureter	0.899	0.101	0.000
G40 Epilepsy	0.894	0.106	0.000
T84.1 Mechanical complication of internal fixation device of bones of limb	0.893	0.107	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.890	0.110	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.887	0.113	0.000
G56 Mononeuropathies of upper limb	0.881	0.119	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.880	0.120	0.000
Z13.9 Special screening examination, unspecified	0.879	0.121	0.000
G40.9 Epilepsy, unspecified	0.872	0.128	0.000
S02 Fracture of skull and facial bones	0.871	0.129	0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.869	0.131	0.000
T78 Adverse effects, not elsewhere classified	0.868	0.132	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.864	0.136	0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.863	0.137	0.000
G56.0 Carpal tunnel syndrome	0.859	0.141	0.000
S06 Intracranial injury	0.855	0.145	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.855	0.145	0.000
S20-S29 Injuries to the thorax	0.849	0.151	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.849	0.151	0.000
N18 Chronic renal failure	0.848	0.152	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.847	0.153	0.000
Z08 Follow-up examination after treatment for malignant neoplasm	0.845	0.155	0.000
S64 Injury of nerves at wrist and hand level	0.844	0.156	0.000
Chapter VII Diseases of the eye and adnexa	0.844	0.156	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.840	0.160	0.000
I33 Acute and subacute endocarditis	0.838	0.162	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.835	0.165	0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.833	0.167	0.000
S90-S99 Injuries to the ankle and foot	0.832	0.168	0.000
W20-W49 Exposure to inanimate mechanical forces	0.829	0.171	0.000
Z60 Problems related to social environment	0.827	0.173	0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.824	0.176	0.000
T84.0 Mechanical complication of internal joint prosthesis	0.822	0.178	0.000
F80-F89 Disorders of psychological development	0.822	0.178	0.000
E21.3 Hyperparathyroidism, unspecified	0.820	0.180	0.000
F31 Bipolar affective disorder	0.820	0.180	0.000
S40-S49 Injuries to the shoulder and upper arm	0.815	0.185	0.000
I44 Atrioventricular and left bundle-branch block	0.815	0.185	0.000
F99-F99 Unspecified mental disorder	0.809	0.191	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.805	0.195	0.000
I05-I09 Chronic rheumatic heart diseases	0.805	0.195	0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.804	0.196	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.802	0.198	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.801	0.198	0.000
Z60.2 Living alone	0.801	0.199	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.800	0.200	0.000
S70-S79 Injuries to the hip and thigh	0.799	0.201	0.000
G51 Facial nerve disorders	0.790	0.210	0.000
T78.4 Allergy, unspecified	0.788	0.212	0.000
G20-G26 Extrapyramidal and movement disorders	0.787	0.213	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.785	0.215	0.000
I35.8 Other aortic valve disorders	0.783	0.217	0.000
T39.1 4-Aminophenol derivatives	0.783	0.217	0.000
Chapter VIII Diseases of the ear and mastoid process	0.782	0.218	0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.782	0.218	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.782	0.218	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.782	0.218	0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.780	0.220	0.000
N80-N98 Noninflammatory disorders of female genital tract	0.778	0.222	0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.777	0.223	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.776	0.223	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.776	0.224	0.000
H55-H59 Other disorders of eye and adnexa	0.775	0.225	0.000
S80-S89 Injuries to the knee and lower leg	0.774	0.226	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.772	0.228	0.000
T84.2 Mechanical complication of internal fixation device of other bones	0.772	0.228	0.000
Y57 Other and unspecified drugs and medicaments	0.772	0.228	0.000
G90-G99 Other disorders of the nervous system	0.772	0.228	0.000
I36 Nonrheumatic tricuspid valve disorders	0.771	0.229	0.000
G30-G32 Other degenerative diseases of the nervous system	0.770	0.230	0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms	0.768	0.232	0.000
Y40 Systemic antibiotics	0.768	0.232	0.000
I35.9 Aortic valve disorder, unspecified	0.767	0.232	0.000
N00-N08 Glomerular diseases	0.767	0.233	0.000
E21.0 Primary hyperparathyroidism	0.766	0.234	0.000
Y52 Agents primarily affecting the cardiovascular system	0.765	0.234	0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.765	0.235	0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.765	0.235	0.000
H40-H42 Glaucoma	0.764	0.236	0.000
T86 Failure and rejection of transplanted organs and tissues	0.764	0.236	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.764	0.236	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.762	0.238	0.000
I74 Arterial embolism and thrombosis	0.760	0.239	0.000
X20-X29 Contact with venomous animals and plants	0.760	0.240	0.000
S10-S19 Injuries to the neck	0.759	0.241	0.000
E73 Lactose intolerance	0.755	0.245	0.000
F60-F69 Disorders of adult personality and behaviour	0.753	0.247	0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.752	0.248	0.000
S60 Superficial injury of wrist and hand	0.752	0.248	0.000
F33 Recurrent depressive disorder	0.751	0.249	0.000
H53-H54 Visual disturbances and blindness	0.750	0.250	0.000
I33.0 Acute and subacute infective endocarditis	0.750	0.250	0.000
Z13.1 Special screening examination for diabetes mellitus	0.749	0.251	0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.749	0.251	0.000
V10-V19 Pedal cyclist injured in transport accident	0.746	0.253	0.000
Chapter II Neoplasms	0.746	0.254	0.000
I35.1 Aortic (valve) insufficiency	0.745	0.255	0.000
N80 Endometriosis	0.745	0.255	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.745	0.255	0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.745	0.255	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.744	0.256	0.000
F06.7 Mild cognitive disorder	0.744	0.256	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.744	0.256	0.000
T84.3 Mechanical complication of other bone devices, implants and grafts	0.740	0.259	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.741	0.259	0.000
Z09.9 Follow-up examination after unspecified treatment for other conditions	0.740	0.260	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.740	0.260	0.000
Chapter XXII Codes for special purposes	0.738	0.261	0.000
I42 Cardiomyopathy	0.738	0.262	0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.737	0.263	0.000
S61.7 Multiple open wounds of wrist and hand	0.735	0.265	0.000
E83.5 Disorders of calcium metabolism	0.734	0.266	0.000
J45 Asthma	0.014	0.266	0.720
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.734	0.266	0.000
I44.0 Atrioventricular block, first degree	0.732	0.268	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.731	0.269	0.000
I72 Other aneurysm	0.729	0.270	0.000
E29 Testicular dysfunction	0.729	0.271	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.727	0.273	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.724	0.275	0.000
W00-W19 Falls	0.724	0.276	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.723	0.276	0.000
S02.4 Fracture of malar and maxillary bones	0.723	0.277	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.723	0.277	0.000
E88 Other metabolic disorders	0.723	0.277	0.000
E40-E46 Malnutrition	0.723	0.277	0.000
N18.9 Chronic renal failure, unspecified	0.722	0.278	0.000
E78.0 Pure hypercholesterolaemia	0.722	0.278	0.000
F41 Other anxiety disorders	0.720	0.280	0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.719	0.280	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.719	0.281	0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.718	0.282	0.000
F43 Reaction to severe stress, and adjustment disorders	0.718	0.282	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.718	0.282	0.000
N99-N99 Other disorders of the genitourinary system	0.718	0.282	0.000
T79-T79 Certain early complications of trauma	0.717	0.283	0.000
T33-T35 Frostbite	0.717	0.283	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.717	0.283	0.000
T00-T07 Injuries involving multiple body regions	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
S69 Other and unspecified injuries of wrist and hand	0.717	0.283	0.000
S65 Injury of blood vessels at wrist and hand level	0.717	0.283	0.000
T78.0 Anaphylactic shock due to adverse food reaction	0.717	0.283	0.000
N80.0 Endometriosis of uterus	0.716	0.284	0.000
I51 Complications and ill-defined descriptions of heart disease	0.716	0.284	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.715	0.285	0.000
N22 Calculus of urinary tract in diseases classified elsewhere	0.715	0.285	0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.715	0.285	0.000
T78.1 Other adverse food reactions, not elsewhere classified	0.714	0.286	0.000
S64.0 Injury of ulnar nerve at wrist and hand level	0.714	0.286	0.000
S68 Traumatic amputation of wrist and hand	0.714	0.286	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.714	0.286	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.713	0.287	0.000
F70-F79 Mental retardation	0.713	0.287	0.000
N20.9 Urinary calculus, unspecified	0.713	0.287	0.000
X60-X84 Intentional self-harm	0.713	0.287	0.000
I46 Cardiac arrest	0.712	0.288	0.000
E85 Amyloidosis	0.711	0.289	0.000
E84 Cystic fibrosis	0.711	0.289	0.000
E79 Disorders of purine and pyrimidine metabolism	0.711	0.289	0.000
E77 Disorders of glycoprotein metabolism	0.711	0.289	0.000
E76 Disorders of glycosaminoglycan metabolism	0.711	0.289	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.711	0.289	0.000
E74 Other disorders of carbohydrate metabolism	0.711	0.289	0.000
E72 Other disorders of amino-acid metabolism	0.711	0.289	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.711	0.289	0.000
E70 Disorders of aromatic amino-acid metabolism	0.711	0.289	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.711	0.289	0.000
N18.3 Chronic kidney disease, stage 3	0.710	0.290	0.000
Z63 Other problems related to primary support group, including family circumstances	0.710	0.290	0.000
V20-V29 Motorcycle rider injured in transport accident	0.709	0.291	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.709	0.291	0.000
E83.8 Other disorders of mineral metabolism	0.709	0.291	0.000
E83.3 Disorders of phosphorus metabolism	0.709	0.291	0.000
E83.2 Disorders of zinc metabolism	0.709	0.291	0.000
E83.0 Disorders of copper metabolism	0.709	0.291	0.000
S06.5 Traumatic subdural haemorrhage	0.709	0.291	0.000
E50-E64 Other nutritional deficiencies	0.708	0.292	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.708	0.292	0.000
Z13.5 Special screening examination for eye and ear disorders	0.708	0.292	0.000
S06.3 Focal brain injury	0.707	0.293	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.707	0.293	0.000
S82 Fracture of lower leg, including ankle	0.707	0.293	0.000
G51.0 Bell's palsy	0.707	0.293	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.707	0.293	0.000
H40 Glaucoma	0.707	0.293	0.000
G54 Nerve root and plexus disorders	0.705	0.295	0.000
N92 Excessive, frequent and irregular menstruation	0.704	0.296	0.000
T87 Complications peculiar to reattachment and amputation	0.704	0.296	0.000
W29 Contact with other powered hand tools and household machinery	0.704	0.296	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.704	0.296	0.000
N25-N29 Other disorders of kidney and ureter	0.702	0.298	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.702	0.298	0.000
Y35-Y36 Legal intervention and operations of war	0.702	0.298	0.000
Y10-Y34 Event of undetermined intent	0.702	0.298	0.000
Y00-Y09 Assault	0.702	0.298	0.000
X85-X99 Assault	0.702	0.298	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.702	0.298	0.000
X50-X57 Overexertion, travel and privation	0.702	0.298	0.000
X30-X39 Exposure to forces of nature	0.702	0.298	0.000
X10-X19 Contact with heat and hot substances	0.702	0.298	0.000
X00-X09 Exposure to smoke, fire and flames	0.702	0.298	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.702	0.298	0.000
W75-W84 Other accidental threats to breathing	0.702	0.298	0.000
W65-W74 Accidental drowning and submersion	0.702	0.298	0.000
W50-W64 Exposure to animate mechanical forces	0.702	0.298	0.000
V98-V99 Other and unspecified transport accidents	0.702	0.298	0.000
V95-V97 Air and space transport accidents	0.702	0.298	0.000
V90-V94 Water transport accidents	0.702	0.298	0.000
V70-V79 Bus occupant injured in transport accident	0.702	0.298	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.702	0.298	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.702	0.298	0.000
V40-V49 Car occupant injured in transport accident	0.702	0.298	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.702	0.298	0.000
V01-V09 Pedestrian injured in transport accident	0.702	0.298	0.000
S67 Crushing injury of wrist and hand	0.701	0.299	0.000
S02.8 Fractures of other skull and facial bones	0.701	0.299	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.701	0.299	0.000
E65-E68 Obesity and other hyperalimentation	0.701	0.299	0.000
S62 Fracture at wrist and hand level	0.700	0.300	0.000
I00-I02 Acute rheumatic fever	0.699	0.301	0.000
I44.1 Atrioventricular block, second degree	0.699	0.301	0.000
F32 Depressive episode	0.698	0.302	0.000
H65-H75 Diseases of middle ear and mastoid	0.698	0.302	0.000
V80-V89 Other land transport accidents	0.697	0.302	0.000
F20 Schizophrenia	0.697	0.303	0.000
S42 Fracture of shoulder and upper arm	0.697	0.303	0.000
H53 Visual disturbances	0.697	0.303	0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.696	0.304	0.000
I78 Diseases of capillaries	0.696	0.304	0.000
G47 Sleep disorders	0.695	0.305	0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm	0.694	0.306	0.000
S02.0 Fracture of vault of skull	0.694	0.306	0.000
E28 Ovarian dysfunction	0.693	0.307	0.000
F40 Phobic anxiety disorders	0.693	0.307	0.000
I70 Atherosclerosis	0.693	0.307	0.000
N10-N16 Renal tubulo-interstitial diseases	0.691	0.309	0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.690	0.310	0.000
S66.8 Injury of other muscles and tendons at wrist and hand level	0.690	0.310	0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.690	0.310	0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.690	0.310	0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.690	0.310	0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.690	0.310	0.000
Y83.2 Surgical operation with anastomosis, bypass or graft	0.690	0.310	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.690	0.310	0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.689	0.311	0.000
I52 Other heart disorders in diseases classified elsewhere	0.688	0.312	0.000
I48 Atrial fibrillation and flutter	0.688	0.312	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.688	0.312	0.000
I41 Myocarditis in diseases classified elsewhere	0.688	0.312	0.000
I40 Acute myocarditis	0.688	0.312	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.688	0.312	0.000
I37 Pulmonary valve disorders	0.688	0.312	0.000
I32 Pericarditis in diseases classified elsewhere	0.688	0.312	0.000
Z04 Examination and observation for other reasons	0.688	0.312	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.687	0.313	0.000
S02.1 Fracture of base of skull	0.687	0.313	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.686	0.314	0.000
S61.1 Open wound of finger(s) with damage to nail	0.685	0.315	0.000
E78.5 Hyperlipidaemia, unspecified	0.684	0.316	0.000
Chapter X Diseases of the respiratory system	0.681	0.317	0.003
S02.3 Fracture of orbital floor	0.683	0.317	0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.682	0.318	0.000
T88.4 Failed or difficult intubation	0.682	0.318	0.000
O00-O08 Pregnancy with abortive outcome	0.682	0.318	0.000
S50-S59 Injuries to the elbow and forearm	0.682	0.318	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.681	0.319	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.681	0.319	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.681	0.319	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.681	0.319	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.681	0.319	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.681	0.319	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.681	0.319	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.681	0.319	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.681	0.319	0.000
T36 Poisoning by systemic antibiotics	0.681	0.319	0.000
I30 Acute pericarditis	0.679	0.321	0.000
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm	0.678	0.322	0.000
G70-G73 Diseases of myoneural junction and muscle	0.678	0.322	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.677	0.323	0.000
N17 Acute renal failure	0.677	0.323	0.000
F99 Mental disorder, not otherwise specified	0.676	0.324	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.673	0.326	0.000
N18.2 Chronic kidney disease, stage 2	0.673	0.327	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.672	0.328	0.000
E34 Other endocrine disorders	0.672	0.328	0.000
E32 Diseases of thymus	0.672	0.328	0.000
E31 Polyglandular dysfunction	0.672	0.328	0.000
E30 Disorders of puberty, not elsewhere classified	0.672	0.328	0.000
E27 Other disorders of adrenal gland	0.672	0.328	0.000
E26 Hyperaldosteronism	0.672	0.328	0.000
E25 Adrenogenital disorders	0.672	0.328	0.000
E24 Cushing's syndrome	0.672	0.328	0.000
E20 Hypoparathyroidism	0.672	0.328	0.000
N80.1 Endometriosis of ovary	0.671	0.329	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.669	0.331	0.000
S08 Traumatic amputation of part of head	0.668	0.332	0.000
S07 Crushing injury of head	0.668	0.332	0.000
S05 Injury of eye and orbit	0.668	0.332	0.000
S04 Injury of cranial nerves	0.668	0.332	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.668	0.332	0.000
T39.0 Salicylates	0.668	0.332	0.000
S91 Open wound of ankle and foot	0.667	0.332	0.000
Z13.6 Special screening examination for cardiovascular disorders	0.667	0.333	0.000
N70-N77 Inflammatory diseases of female pelvic organs	0.667	0.333	0.000
I47 Paroxysmal tachycardia	0.665	0.335	0.000
Y57.9 Drug or medicament, unspecified	0.665	0.335	0.000
N89 Other noninflammatory disorders of vagina	0.665	0.335	0.000
H57 Other disorders of eye and adnexa	0.664	0.336	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.663	0.337	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.662	0.338	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.662	0.338	0.000
T75 Effects of other external causes	0.662	0.338	0.000
T74 Maltreatment syndromes	0.662	0.338	0.000
T73 Effects of other deprivation	0.662	0.338	0.000
T70 Effects of air pressure and water pressure	0.662	0.338	0.000
T69 Other effects of reduced temperature	0.662	0.338	0.000
T67 Effects of heat and light	0.662	0.338	0.000
T71 Asphyxiation	0.662	0.338	0.000
T68 Hypothermia	0.662	0.338	0.000
T66 Unspecified effects of radiation	0.662	0.338	0.000
F45 Somatoform disorders	0.662	0.338	0.000
F25 Schizoaffective disorders	0.661	0.339	0.000
Y59 Other and unspecified vaccines and biological substances	0.660	0.340	0.000
Y58 Bacterial vaccines	0.660	0.340	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.660	0.340	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.660	0.340	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.660	0.340	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.660	0.340	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.660	0.340	0.000
Y48 Anaesthetics and therapeutic gases	0.660	0.340	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.660	0.340	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.660	0.340	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.660	0.340	0.000
E23 Hypofunction and other disorders of pituitary gland	0.660	0.340	0.000
G46 Vascular syndromes of brain in cerebrovascular diseases	0.659	0.340	0.000
G41 Status epilepticus	0.659	0.340	0.000
F38 Other mood [affective] disorders	0.659	0.341	0.000
F34 Persistent mood [affective] disorders	0.659	0.341	0.000
F30 Manic episode	0.659	0.341	0.000
F39 Unspecified mood [affective] disorder	0.659	0.341	0.000
F84 Pervasive developmental disorders	0.658	0.341	0.000
G56.2 Lesion of ulnar nerve	0.658	0.342	0.000
S01 Open wound of head	0.658	0.342	0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.657	0.343	0.000
I71.0 Dissection of aorta [any part]	0.656	0.344	0.000
Y44 Agents primarily affecting blood constituents	0.653	0.347	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.652	0.347	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.652	0.347	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.652	0.347	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.652	0.347	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.652	0.347	0.000
G58 Other mononeuropathies	0.650	0.349	0.000
G53 Cranial nerve disorders in diseases classified elsewhere	0.650	0.349	0.000
G52 Disorders of other cranial nerves	0.650	0.349	0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.650	0.350	0.000
N92.0 Excessive and frequent menstruation with regular cycle	0.650	0.350	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.649	0.351	0.000
I31 Other diseases of pericardium	0.647	0.353	0.000
H40.1 Primary open-angle glaucoma	0.647	0.353	0.000
Z10 Routine general health check-up of defined subpopulation	0.646	0.354	0.000
F81 Specific developmental disorders of scholastic skills	0.645	0.355	0.000
Z13.8 Special screening examination for other specified diseases and disorders	0.645	0.355	0.000
Z13.7 Special screening examination for congenital malformations, deformations and chromosomal abnormalities	0.645	0.355	0.000
Z13.4 Special screening examination for certain developmental disorders in childhood	0.645	0.355	0.000
Z13.3 Special screening examination for mental and behavioural disorders	0.645	0.355	0.000
Z13.2 Special screening examination for nutritional disorders	0.645	0.355	0.000
N95 Menopausal and other perimenopausal disorders	0.644	0.356	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.644	0.356	0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.643	0.357	0.000
I08 Multiple valve diseases	0.642	0.358	0.000
F22 Persistent delusional disorders	0.642	0.358	0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.641	0.359	0.000
T92 Sequelae of injuries of upper limb	0.641	0.359	0.000
G40.8 Other epilepsy	0.641	0.359	0.000
G40.7 Petit mal, unspecified, without grand mal seizures	0.641	0.359	0.000
G40.5 Special epileptic syndromes	0.641	0.359	0.000
G40.4 Other generalised epilepsy and epileptic syndromes	0.641	0.359	0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.641	0.359	0.000
Z11 Special screening examination for infectious and parasitic diseases	0.640	0.360	0.000
S99 Other and unspecified injuries of ankle and foot	0.640	0.360	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.640	0.360	0.000
S64.4 Injury of digital nerve of other finger	0.639	0.361	0.000
F33.9 Recurrent depressive disorder, unspecified	0.639	0.361	0.000
E22 Hyperfunction of pituitary gland	0.638	0.362	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.638	0.362	0.000
E21.4 Other specified disorders of parathyroid gland	0.638	0.362	0.000
E21.2 Other hyperparathyroidism	0.638	0.362	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.638	0.362	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.638	0.362	0.000
W22 Striking against or struck by other objects	0.637	0.362	0.000
S06.2 Diffuse brain injury	0.637	0.363	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.636	0.364	0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.636	0.364	0.000
F48 Other neurotic disorders	0.636	0.364	0.000
F44 Dissociative [conversion] disorders	0.636	0.364	0.000
F42 Obsessive-compulsive disorder	0.636	0.364	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.635	0.365	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.634	0.365	0.001
G44 Other headache syndromes	0.633	0.367	0.000
I44.3 Other and unspecified atrioventricular block	0.632	0.367	0.000
E89.2 Postprocedural hypoparathyroidism	0.632	0.368	0.000
G56.9 Mononeuropathy of upper limb, unspecified	0.631	0.369	0.000
G56.8 Other mononeuropathies of upper limb	0.631	0.369	0.000
G56.4 Causalgia	0.631	0.369	0.000
G56.3 Lesion of radial nerve	0.631	0.369	0.000
G56.1 Other lesions of median nerve	0.631	0.369	0.000
F41.2 Mixed anxiety and depressive disorder	0.631	0.369	0.000
N21 Calculus of lower urinary tract	0.631	0.369	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.631	0.369	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.631	0.369	0.000
T39.4 Antirheumatics, not elsewhere classified	0.631	0.369	0.000
T39.2 Pyrazolone derivatives	0.631	0.369	0.000
H53.0 Amblyopia ex anopsia	0.629	0.371	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.629	0.371	0.000
S02.2 Fracture of nasal bones	0.628	0.372	0.000
Z09.8 Follow-up examination after other treatment for other conditions	0.627	0.372	0.000
N03 Chronic nephritic syndrome	0.627	0.373	0.000
H10-H13 Disorders of conjunctiva	0.627	0.373	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.626	0.374	0.000
T23 Burn and corrosion of wrist and hand	0.625	0.375	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.624	0.375	0.000
S02.7 Multiple fractures involving skull and facial bones	0.624	0.375	0.000
S02.5 Fracture of tooth	0.624	0.375	0.000
I77 Other disorders of arteries and arterioles	0.624	0.376	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.624	0.376	0.000
C15-C26 Malignant neoplasms of digestive organs	0.624	0.376	0.000
Q60-Q64 Congenital malformations of the urinary system	0.624	0.376	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.624	0.376	0.000
T78.9 Adverse effect, unspecified	0.622	0.378	0.000
T78.8 Other adverse effects, not elsewhere classified	0.622	0.378	0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.622	0.378	0.000
H53.8 Other visual disturbances	0.622	0.378	0.000
S82.5 Fracture of medial malleolus	0.620	0.380	0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.620	0.380	0.000
T85.2 Mechanical complication of intraocular lens	0.620	0.380	0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.620	0.380	0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.620	0.380	0.000
N82 Fistulae involving female genital tract	0.620	0.380	0.000
Z65 Problems related to other psychosocial circumstances	0.619	0.381	0.000
Z64 Problems related to certain psychosocial circumstances	0.619	0.381	0.000
Z62 Other problems related to upbringing	0.619	0.381	0.000
Z61 Problems related to negative life events in childhood	0.619	0.381	0.000
Z59 Problems related to housing and economic circumstances	0.619	0.381	0.000
Z58 Problems related to physical environment	0.619	0.381	0.000
Z56 Problems related to employment and unemployment	0.619	0.381	0.000
Z55 Problems related to education and literacy	0.619	0.381	0.000
S92 Fracture of foot, except ankle	0.618	0.382	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.618	0.382	0.000
S70 Superficial injury of hip and thigh	0.618	0.382	0.000
E86 Volume depletion	0.618	0.382	0.000
F31.9 Bipolar affective disorder, unspecified	0.617	0.383	0.000
Y40.9 Systemic antibiotic, unspecified	0.617	0.383	0.000
C44 Other malignant neoplasms of skin	0.617	0.383	0.000
J30-J39 Other diseases of upper respiratory tract	0.616	0.383	0.000
S82.8 Fractures of other parts of lower leg	0.616	0.384	0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.616	0.384	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations