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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs11634027
log Bayes Factor = 15.0934
Chromosome 15   position 26,637,415  (GRCh37) Explore rs11634027 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
0.999 0.001 0.000
Chapter V Mental and behavioural disorders
0.999 0.001 0.000
Chapter X Diseases of the respiratory system
0.998 0.002 0.000
M20-M25 Other joint disorders
0.998 0.002 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.998 0.002 0.000
Chapter IX Diseases of the circulatory system
0.997 0.003 0.000
Chapter VII Diseases of the eye and adnexa
0.997 0.003 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.997 0.003 0.000
I20-I25 Ischaemic heart diseases
0.996 0.004 0.000
M23 Internal derangement of knee
0.996 0.004 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.989 0.011 0.000
I20 Angina pectoris
0.989 0.011 0.000
J40-J47 Chronic lower respiratory diseases
0.989 0.011 0.000
M45-M49 Spondylopathies
0.986 0.014 0.000
N30-N39 Other diseases of urinary system
0.983 0.017 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.980 0.020 0.000
I20.0 Unstable angina
0.979 0.021 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.976 0.024 0.000
J44 Other chronic obstructive pulmonary disease
0.969 0.031 0.000
M70-M79 Other soft tissue disorders
0.968 0.032 0.000
Chapter VI Diseases of the nervous system
0.967 0.033 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.959 0.041 0.000
M47 Spondylosis
0.958 0.042 0.000
N39 Other disorders of urinary system
0.957 0.043 0.000
N93 Other abnormal uterine and vaginal bleeding
0.951 0.049 0.000
N93.9 Abnormal uterine and vaginal bleeding, unspecified
0.950 0.050 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.943 0.057 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.942 0.058 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.941 0.059 0.000
F30-F39 Mood [affective] disorders
0.938 0.062 0.000
T42.4 Benzodiazepines
0.933 0.067 0.000
H30-H36 Disorders of choroid and retina
0.933 0.067 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.932 0.068 0.000
Chapter I Certain infectious and parasitic diseases
0.932 0.068 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.930 0.070 0.000
J47 Bronchiectasis
0.928 0.072 0.000
I24 Other acute ischaemic heart diseases
0.924 0.076 0.000
F10.2 Dependence syndrome
0.923 0.077 0.000
J30-J39 Other diseases of upper respiratory tract
0.920 0.080 0.000
N39.4 Other specified urinary incontinence
0.917 0.083 0.000
H53-H54 Visual disturbances and blindness
0.916 0.084 0.000
M23.8 Other internal derangements of knee
0.916 0.084 0.000
S00-S09 Injuries to the head
0.915 0.085 0.000
N30 Cystitis
0.912 0.088 0.000
T43.2 Other and unspecified antidepressants
0.906 0.094 0.000
H33 Retinal detachments and breaks
0.903 0.097 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.899 0.101 0.000
M50-M54 Other dorsopathies
0.898 0.102 0.000
N80 Endometriosis
0.898 0.102 0.000
N10-N16 Renal tubulo-interstitial diseases
0.897 0.103 0.000
I77 Other disorders of arteries and arterioles
0.893 0.107 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.892 0.108 0.000
H43-H45 Disorders of vitreous body and globe
0.892 0.108 0.000
M47.8 Other spondylosis
0.890 0.110 0.000
F10.0 Acute intoxication
0.881 0.119 0.000
M23.3 Other meniscus derangements
0.879 0.121 0.000
F10.1 Harmful use
0.879 0.121 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.878 0.122 0.000
N39.3 Stress incontinence
0.877 0.123 0.000
B35-B49 Mycoses
0.876 0.124 0.000
M48 Other spondylopathies
0.876 0.124 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.874 0.126 0.000
M05-M14 Inflammatory polyarthropathies
0.872 0.128 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.871 0.129 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.871 0.129 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.867 0.133 0.000
A30-A49 Other bacterial diseases
0.866 0.134 0.000
N13 Obstructive and reflux uropathy
0.865 0.135 0.000
G90-G99 Other disorders of the nervous system
0.864 0.136 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.863 0.137 0.000
H33.0 Retinal detachment with retinal break
0.861 0.139 0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.857 0.143 0.000
F32 Depressive episode
0.856 0.144 0.000
I77.1 Stricture of artery
0.855 0.145 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.854 0.146 0.000
I20.8 Other forms of angina pectoris
0.854 0.146 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.853 0.147 0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)
0.850 0.150 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.850 0.150 0.000
F17.1 Harmful use
0.849 0.151 0.000
N30.2 Other chronic cystitis
0.845 0.155 0.000
N83.2 Other and unspecified ovarian cysts
0.845 0.155 0.000
J46 Status asthmaticus
0.844 0.156 0.000
N80.9 Endometriosis, unspecified
0.844 0.156 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.842 0.158 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.842 0.158 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.839 0.161 0.000
M79.8 Other specified soft tissue disorders
0.837 0.163 0.000
I25 Chronic ischaemic heart disease
0.836 0.164 0.000
M76 Enthesopathies of lower limb, excluding foot
0.835 0.164 0.000
B37 Candidiasis
0.833 0.167 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.829 0.171 0.000
H40-H42 Glaucoma
0.828 0.172 0.000
F17.2 Dependence syndrome
0.825 0.175 0.000
I30-I52 Other forms of heart disease
0.825 0.175 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.823 0.177 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.822 0.178 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.822 0.178 0.000
H54 Blindness and low vision
0.819 0.181 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.818 0.182 0.000
M21 Other acquired deformities of limbs
0.817 0.183 0.000
S00 Superficial injury of head
0.814 0.186 0.000
F10.4 Withdrawal state with delirium
0.812 0.188 0.000
M80-M85 Disorders of bone density and structure
0.811 0.189 0.000
S40-S49 Injuries to the shoulder and upper arm
0.809 0.191 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.809 0.191 0.000
S60-S69 Injuries to the wrist and hand
0.807 0.193 0.000
M24 Other specific joint derangements
0.807 0.193 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.805 0.195 0.000
M47.9 Spondylosis, unspecified
0.804 0.196 0.000
J09-J18 Influenza and pneumonia
0.801 0.199 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.801 0.199 0.000
A41 Other septicaemia
0.800 0.200 0.000
S90-S99 Injuries to the ankle and foot
0.800 0.200 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.798 0.202 0.000
M48.0 Spinal stenosis
0.796 0.204 0.000
N60-N64 Disorders of breast
0.796 0.204 0.000
M47.86 Other spondylosis (Lumbar region)
0.793 0.207 0.000
M35 Other systemic involvement of connective tissue
0.790 0.210 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.790 0.210 0.000
J95-J99 Other diseases of the respiratory system
0.790 0.210 0.000
G37 Other demyelinating diseases of central nervous system
0.789 0.211 0.000
M47.2 Other spondylosis with radiculopathy
0.789 0.211 0.000
N00-N08 Glomerular diseases
0.785 0.215 0.000
M75 Shoulder lesions
0.785 0.215 0.000
H55-H59 Other disorders of eye and adnexa
0.784 0.216 0.000
S00.8 Superficial injury of other parts of head
0.784 0.216 0.000
H10-H13 Disorders of conjunctiva
0.782 0.218 0.000
N87 Dysplasia of cervix uteri
0.781 0.219 0.000
J33 Nasal polyp
0.780 0.220 0.000
S02 Fracture of skull and facial bones
0.780 0.220 0.000
Chapter XXII Codes for special purposes
0.779 0.221 0.000
N39.8 Other specified disorders of urinary system
0.777 0.223 0.000
M77 Other enthesopathies
0.776 0.224 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.776 0.224 0.000
M46 Other inflammatory spondylopathies
0.775 0.225 0.000
H25-H28 Disorders of lens
0.775 0.225 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.773 0.226 0.000
M51 Other intervertebral disk disorders
0.773 0.227 0.000
T51 Toxic effect of alcohol
0.772 0.228 0.000
J81 Pulmonary oedema
0.771 0.229 0.000
I73 Other peripheral vascular diseases
0.770 0.230 0.000
M31 Other necrotising vasculopathies
0.769 0.231 0.000
H43 Disorders of vitreous body
0.766 0.234 0.000
B37.8 Candidiasis of other sites
0.764 0.236 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.761 0.239 0.000
H53 Visual disturbances
0.761 0.239 0.000
I78 Diseases of capillaries
0.760 0.240 0.000
I50 Heart failure
0.758 0.242 0.000
F31 Bipolar affective disorder
0.758 0.242 0.000
I24.8 Other forms of acute ischaemic heart disease
0.757 0.243 0.000
J31.0 Chronic rhinitis
0.756 0.244 0.000
N99-N99 Other disorders of the genitourinary system
0.756 0.244 0.000
H34 Retinal vascular occlusions
0.755 0.245 0.000
N73 Other female pelvic inflammatory diseases
0.753 0.247 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.752 0.248 0.000
N80.2 Endometriosis of Fallopian tube
0.752 0.248 0.000
H33.3 Retinal breaks without detachment
0.750 0.250 0.000
I25.2 Old myocardial infarction
0.749 0.251 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.749 0.251 0.000
F10.3 Withdrawal state
0.749 0.251 0.000
M86-M90 Other osteopathies
0.748 0.252 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.746 0.254 0.000
I20.1 Angina pectoris with documented spasm
0.745 0.255 0.000
S70-S79 Injuries to the hip and thigh
0.744 0.256 0.000
M22 Disorders of patella
0.744 0.256 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.744 0.256 0.000
J33.8 Other polyp of sinus
0.741 0.259 0.000
B37.0 Candidal stomatitis
0.741 0.259 0.000
H44 Disorders of globe
0.739 0.261 0.000
I21 Acute myocardial infarction
0.739 0.261 0.000
N88 Other noninflammatory disorders of cervix uteri
0.739 0.261 0.000
M40-M43 Deforming dorsopathies
0.737 0.263 0.000
I05-I09 Chronic rheumatic heart diseases
0.737 0.263 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.736 0.264 0.000
S06 Intracranial injury
0.735 0.265 0.000
N80.8 Other endometriosis
0.735 0.265 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.734 0.266 0.000
T39.0 Salicylates
0.733 0.267 0.000
S20-S29 Injuries to the thorax
0.732 0.268 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.731 0.269 0.000
N13.3 Other and unspecified hydronephrosis
0.731 0.269 0.000
J38.3 Other diseases of vocal cords
0.731 0.269 0.000
F33 Recurrent depressive disorder
0.730 0.270 0.000
M50 Cervical disk disorders
0.730 0.270 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.729 0.271 0.000
J60-J70 Lung diseases due to external agents
0.729 0.271 0.000
G95 Other diseases of spinal cord
0.729 0.271 0.000
N76 Other inflammation of vagina and vulva
0.728 0.272 0.000
N97 Female infertility
0.727 0.273 0.000
M23.5 Chronic instability of knee
0.725 0.275 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.724 0.276 0.000
N39.9 Disorder of urinary system, unspecified
0.724 0.276 0.000
N30.1 Interstitial cystitis (chronic)
0.723 0.277 0.000
M47.82 Other spondylosis (Cervical region)
0.722 0.278 0.000
F32.1 Moderate depressive episode
0.722 0.278 0.000
M47.1 Other spondylosis with myelopathy
0.722 0.278 0.000
I42 Cardiomyopathy
0.721 0.279 0.000
N13.4 Hydroureter
0.721 0.279 0.000
I50.0 Congestive heart failure
0.720 0.280 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.719 0.281 0.000
M10 Gout
0.718 0.282 0.000
G57 Mononeuropathies of lower limb
0.717 0.283 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
F80-F89 Disorders of psychological development
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
M05 Seropositive rheumatoid arthritis
0.717 0.283 0.000
F99-F99 Unspecified mental disorder
0.716 0.284 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.716 0.284 0.000
F70-F79 Mental retardation
0.716 0.284 0.000
F60-F69 Disorders of adult personality and behaviour
0.716 0.284 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.716 0.284 0.000
M34 Systemic sclerosis
0.716 0.284 0.000
M33 Dermatopolymyositis
0.716 0.284 0.000
M32 Systemic lupus erythematosus
0.716 0.284 0.000
M30 Polyarteritis nodosa and related conditions
0.716 0.284 0.000
T91 Sequelae of injuries of neck and trunk
0.716 0.284 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.715 0.285 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.715 0.285 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.715 0.285 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.715 0.285 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.715 0.285 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.715 0.285 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.715 0.285 0.000
T36 Poisoning by systemic antibiotics
0.715 0.285 0.000
I00-I02 Acute rheumatic fever
0.715 0.285 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.715 0.285 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.715 0.285 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.715 0.285 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.715 0.285 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.715 0.285 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.715 0.285 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.715 0.285 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.715 0.285 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.715 0.285 0.000
F11 Mental and behavioural disorders due to use of opioids
0.715 0.285 0.000
I23 Certain current complications following acute myocardial infarction
0.714 0.286 0.000
M23.9 Internal derangement of knee, unspecified
0.714 0.286 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.714 0.286 0.000
M23.1 Discoid meniscus (congenital)
0.714 0.286 0.000
M23.0 Cystic meniscus
0.714 0.286 0.000
M48.06 Spinal stenosis (Lumbar region)
0.713 0.287 0.000
I72 Other aneurysm
0.710 0.290 0.000
B15-B19 Viral hepatitis
0.710 0.290 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.710 0.290 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.709 0.291 0.000
F10.9 Unspecified mental and behavioural disorder
0.709 0.291 0.000
F10.8 Other mental and behavioural disorders
0.709 0.291 0.000
F10.7 Residual and late-onset psychotic disorder
0.709 0.291 0.000
F10.6 Amnesic syndrome
0.709 0.291 0.000
F10.5 Psychotic disorder
0.709 0.291 0.000
J41 Simple and mucopurulent chronic bronchitis
0.709 0.291 0.000
N83.1 Corpus luteum cyst
0.708 0.292 0.000
M49 Spondylopathies in diseases classified elsewhere
0.707 0.293 0.000
H40 Glaucoma
0.707 0.293 0.000
A41.9 Septicaemia, unspecified
0.706 0.294 0.000
N37 Urethral disorders in diseases classified elsewhere
0.705 0.295 0.000
N34 Urethritis and urethral syndrome
0.705 0.295 0.000
N33 Bladder disorders in diseases classified elsewhere
0.705 0.295 0.000
T51.0 Ethanol
0.704 0.296 0.000
H50 Other strabismus
0.704 0.296 0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular
0.703 0.297 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.702 0.298 0.000
M72 Fibroblastic disorders
0.701 0.298 0.000
M76.8 Other enthesopathies of lower limb, excluding foot
0.700 0.300 0.000
N20-N23 Urolithiasis
0.700 0.300 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.700 0.300 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.700 0.300 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.700 0.300 0.000
T42.3 Barbiturates
0.700 0.300 0.000
T42.2 Succinimides and oxazolidinediones
0.700 0.300 0.000
T42.1 Iminostilbenes
0.700 0.300 0.000
T42.0 Hydantoin derivatives
0.700 0.300 0.000
M75.1 Rotator cuff syndrome
0.699 0.301 0.000
J40 Bronchitis, not specified as acute or chronic
0.698 0.302 0.000
I46 Cardiac arrest
0.697 0.303 0.000
I21.9 Acute myocardial infarction, unspecified
0.696 0.304 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.696 0.304 0.000
J43 Emphysema
0.695 0.305 0.000
N13.8 Other obstructive and reflux uropathy
0.695 0.305 0.000
J32 Chronic sinusitis
0.694 0.305 0.000
M51.2 Other specified intervertebral disk displacement
0.695 0.305 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.694 0.305 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.694 0.306 0.000
M71 Other bursopathies
0.694 0.306 0.000
H53.0 Amblyopia ex anopsia
0.694 0.306 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.693 0.307 0.000
N36 Other disorders of urethra
0.693 0.307 0.000
G70-G73 Diseases of myoneural junction and muscle
0.692 0.308 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.691 0.309 0.000
M20 Acquired deformities of fingers and toes
0.690 0.310 0.000
S68 Traumatic amputation of wrist and hand
0.689 0.311 0.000
G93 Other disorders of brain
0.689 0.311 0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified
0.688 0.312 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.688 0.312 0.000
N98 Complications associated with artificial fertilisation
0.687 0.312 0.000
N91 Absent, scanty and rare menstruation
0.687 0.312 0.000
N82 Fistulae involving female genital tract
0.687 0.312 0.000
N96 Habitual aborter
0.687 0.312 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.687 0.313 0.000
M13 Other arthritis
0.687 0.313 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.686 0.313 0.000
N39.2 Orthostatic proteinuria, unspecified
0.686 0.314 0.000
N39.1 Persistent proteinuria, unspecified
0.686 0.314 0.000
H33.2 Serous retinal detachment
0.686 0.314 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.684 0.316 0.000
M65-M68 Disorders of synovium and tendon
0.684 0.316 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.682 0.318 0.000
J39 Other diseases of upper respiratory tract
0.681 0.318 0.000
A46 Erysipelas
0.681 0.319 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.678 0.322 0.000
N30.0 Acute cystitis
0.677 0.322 0.000
N64 Other disorders of breast
0.676 0.324 0.000
T43.9 Psychotropic drug, unspecified
0.676 0.324 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.676 0.324 0.000
T43.6 Psychostimulants with abuse potential
0.676 0.324 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.676 0.324 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.676 0.324 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.676 0.324 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.676 0.324 0.000
M45 Ankylosing spondylitis
0.675 0.324 0.000
H54.9 Unspecified visual impairment (binocular)
0.675 0.324 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.675 0.325 0.000
H52 Disorders of refraction and accommodation
0.675 0.325 0.000
F17.9 Unspecified mental and behavioural disorder
0.675 0.325 0.000
F17.8 Other mental and behavioural disorders
0.675 0.325 0.000
F17.7 Residual and late-onset psychotic disorder
0.675 0.325 0.000
F17.6 Amnesic syndrome
0.675 0.325 0.000
F17.5 Psychotic disorder
0.675 0.325 0.000
F17.4 Withdrawal state with delirium
0.675 0.325 0.000
F17.3 Withdrawal state
0.675 0.325 0.000
F17.0 Acute intoxication
0.675 0.325 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.674 0.325 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.674 0.326 0.000
N30.8 Other cystitis
0.674 0.326 0.000
M23.4 Loose body in knee
0.674 0.326 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.674 0.326 0.000
T90 Sequelae of injuries of head
0.674 0.326 0.000
F38 Other mood [affective] disorders
0.673 0.327 0.000
F34 Persistent mood [affective] disorders
0.673 0.327 0.000
F30 Manic episode
0.673 0.327 0.000
F39 Unspecified mood [affective] disorder
0.673 0.327 0.000
H54.7 Unspecified visual loss
0.672 0.328 0.000
N30.3 Trigonitis
0.672 0.328 0.000
M54 Dorsalgia
0.672 0.328 0.000
J31.2 Chronic pharyngitis
0.672 0.328 0.000
J30 Vasomotor and allergic rhinitis
0.671 0.329 0.000
H26 Other cataract
0.671 0.329 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.670 0.330 0.000
I22 Subsequent myocardial infarction
0.670 0.330 0.000
M24.1 Other articular cartilage disorders
0.669 0.331 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.669 0.331 0.000
H31 Other disorders of choroid
0.669 0.331 0.000
H30 Chorioretinal inflammation
0.669 0.331 0.000
M76.6 Achilles tendinitis
0.669 0.331 0.000
M80 Osteoporosis with pathological fracture
0.669 0.331 0.000
T66-T78 Other and unspecified effects of external causes
0.668 0.331 0.000
B99-B99 Other infectious diseases
0.668 0.332 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.668 0.332 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.668 0.332 0.000
B65-B83 Helminthiases
0.668 0.332 0.000
B50-B64 Protozoal diseases
0.668 0.332 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.668 0.332 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.668 0.332 0.000
A80-A89 Viral infections of the central nervous system
0.668 0.332 0.000
A75-A79 Rickettsioses
0.668 0.332 0.000
A70-A74 Other diseases caused by chlamydiae
0.668 0.332 0.000
A65-A69 Other spirochaetal diseases
0.668 0.332 0.000
A20-A28 Certain zoonotic bacterial diseases
0.668 0.332 0.000
A15-A19 Tuberculosis
0.668 0.332 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.667 0.333 0.000
N75 Diseases of Bartholin's gland
0.667 0.333 0.000
T45.5 Anticoagulants
0.667 0.333 0.000
N83.9 Noninflammatory disorder of ovary, Fallopian tube and broad ligament, unspecified
0.667 0.333 0.000
N83.7 Haematoma of broad ligament
0.667 0.333 0.000
N83.6 Haematosalpinx
0.667 0.333 0.000
N83.5 Torsion of ovary, ovarian pedicle and Fallopian tube
0.667 0.333 0.000
N83.4 Prolapse and hernia of ovary and Fallopian tube
0.667 0.333 0.000
N83.3 Acquired atrophy of ovary and Fallopian tube
0.667 0.333 0.000
G35 Multiple sclerosis
0.666 0.334 0.000
G58 Other mononeuropathies
0.666 0.334 0.000
N40-N51 Diseases of male genital organs
0.665 0.335 0.000
I42.9 Cardiomyopathy, unspecified
0.665 0.335 0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)
0.665 0.335 0.000
Chapter VIII Diseases of the ear and mastoid process
0.665 0.335 0.000
N72 Inflammatory disease of cervix uteri
0.663 0.337 0.000
I24.1 Dressler's syndrome
0.663 0.337 0.000
Chapter XX External causes of morbidity and mortality
0.662 0.338 0.000
J90-J94 Other diseases of pleura
0.661 0.339 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.661 0.339 0.000
S01 Open wound of head
0.661 0.339 0.000
J37 Chronic laryngitis and laryngotracheitis
0.660 0.340 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.659 0.341 0.000
I70 Atherosclerosis
0.659 0.341 0.000
N71 Inflammatory disease of uterus, except cervix
0.657 0.343 0.000
M23.87 Other internal derangements of knee (Capsular ligament)
0.656 0.343 0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)
0.656 0.343 0.000
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)
0.656 0.343 0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.656 0.343 0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.656 0.343 0.000
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.656 0.343 0.000
M23.80 Other internal derangements of knee (Multiple sites)
0.656 0.343 0.000
N83.0 Follicular cyst of ovary
0.656 0.343 0.000
S08 Traumatic amputation of part of head
0.656 0.344 0.000
S07 Crushing injury of head
0.656 0.344 0.000
S05 Injury of eye and orbit
0.656 0.344 0.000
S04 Injury of cranial nerves
0.656 0.344 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.656 0.344 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.656 0.344 0.000
J38.4 Oedema of larynx
0.655 0.345 0.000
N30.4 Irradiation cystitis
0.654 0.346 0.000
G91 Hydrocephalus
0.653 0.347 0.000
T93 Sequelae of injuries of lower limb
0.652 0.348 0.000
B25-B34 Other viral diseases
0.652 0.348 0.000
H43.9 Disorder of vitreous body, unspecified
0.652 0.348 0.000
G51 Facial nerve disorders
0.651 0.348 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.651 0.349 0.000
I20.9 Angina pectoris, unspecified
0.651 0.349 0.000
N80.3 Endometriosis of pelvic peritoneum
0.650 0.349 0.000
G56 Mononeuropathies of upper limb
0.650 0.350 0.000
M35.0 Sicca syndrome [Sjogren]
0.650 0.350 0.000
H33.5 Other retinal detachments
0.647 0.352 0.000
H33.4 Traction detachment of retina
0.647 0.352 0.000
H33.1 Retinoschisis and retinal cysts
0.647 0.352 0.000
J84 Other interstitial pulmonary diseases
0.647 0.352 0.000
S50-S59 Injuries to the elbow and forearm
0.647 0.353 0.000
S67 Crushing injury of wrist and hand
0.645 0.355 0.000
J00-J06 Acute upper respiratory infections
0.645 0.355 0.000
J20-J22 Other acute lower respiratory infections
0.645 0.355 0.000
N87.2 Severe cervical dysplasia, not elsewhere classified
0.645 0.355 0.000
H43.3 Other vitreous opacities
0.644 0.356 0.000
M53 Other dorsopathies, not elsewhere classified
0.644 0.356 0.000
N80.6 Endometriosis in cutaneous scar
0.644 0.356 0.000
N80.5 Endometriosis of intestine
0.644 0.356 0.000
N80.4 Endometriosis of rectovaginal septum and vagina
0.644 0.356 0.000
B35 Dermatophytosis
0.643 0.356 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.643 0.357 0.000
N15 Other renal tubulo-interstitial diseases
0.643 0.357 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.643 0.357 0.000
N11 Chronic tubulo-interstitial nephritis
0.643 0.357 0.000
N10 Acute tubulo-interstitial nephritis
0.643 0.357 0.000
B37.3 Candidiasis of vulva and vagina
0.642 0.358 0.000
J42 Unspecified chronic bronchitis
0.641 0.358 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.642 0.358 0.000
G20-G26 Extrapyramidal and movement disorders
0.641 0.358 0.000
I77.8 Other specified disorders of arteries and arterioles
0.640 0.360 0.000
I77.5 Necrosis of artery
0.640 0.360 0.000
I77.4 Coeliac artery compression syndrome
0.640 0.360 0.000
I77.3 Arterial fibromuscular dysplasia
0.640 0.360 0.000
I77.2 Rupture of artery
0.640 0.360 0.000
I77.0 Arteriovenous fistula, acquired
0.640 0.360 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.640 0.360 0.000
N73.9 Female pelvic inflammatory disease, unspecified
0.640 0.360 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.639 0.361 0.000
N87.0 Mild cervical dysplasia
0.639 0.361 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.639 0.361 0.000
S32 Fracture of lumbar spine and pelvis
0.638 0.362 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.638 0.362 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.638 0.362 0.000
M47.84 Other spondylosis (Thoracic region)
0.638 0.362 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.638 0.362 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.638 0.362 0.000
G96 Other disorders of central nervous system
0.637 0.363 0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.637 0.363 0.000
M21.1 Varus deformity, not elsewhere classified
0.637 0.363 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.636 0.364 0.000
M21.6 Other acquired deformities of ankle and foot
0.635 0.365 0.000
G12 Spinal muscular atrophy and related syndromes
0.635 0.365 0.000
A49 Bacterial infection of unspecified site
0.634 0.366 0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)
0.633 0.367 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.632 0.368 0.000
G95.2 Cord compression, unspecified
0.631 0.369 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.630 0.369 0.000
M23.37 Other meniscus derangements-Capsular lig
0.630 0.369 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.630 0.369 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.630 0.369 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.630 0.369 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.630 0.370 0.000
I78.1 Naevus, nonneoplastic
0.630 0.370 0.000
M47.89 Other spondylosis (Site unspecified)
0.629 0.371 0.000
H34.8 Other retinal vascular occlusions
0.628 0.372 0.000
B48 Other mycoses, not elsewhere classified
0.628 0.372 0.000
B47 Mycetoma
0.628 0.372 0.000
B46 Zygomycosis
0.628 0.372 0.000
B45 Cryptococcosis
0.628 0.372 0.000
B44 Aspergillosis
0.628 0.372 0.000
B43 Chromomycosis and phaeomycotic abscess
0.628 0.372 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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