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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs116352995
log Bayes Factor = 14.9627
Chromosome 14   position 49,355,219  (GRCh37) Explore rs116352995 on Ensembl!
Variant rs116352995 is part of Cluster X0044

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
D10-D36 Benign neoplasms
0.997 0.003 0.000
Chapter XXI Factors influencing health status and contact with health services
0.996 0.004 0.000
Chapter X Diseases of the respiratory system
0.989 0.011 0.000
K90-K93 Other diseases of the digestive system
0.985 0.015 0.000
S00-S09 Injuries to the head
0.983 0.017 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.979 0.021 0.000
Chapter VI Diseases of the nervous system
0.972 0.028 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.972 0.028 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.969 0.031 0.000
M20-M25 Other joint disorders
0.963 0.037 0.000
D17 Benign lipomatous neoplasm
0.962 0.038 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.960 0.040 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.957 0.043 0.000
K80 Cholelithiasis
0.953 0.047 0.000
J95-J99 Other diseases of the respiratory system
0.951 0.049 0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
0.946 0.054 0.000
L60-L75 Disorders of skin appendages
0.945 0.055 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.940 0.060 0.000
Z51 Other medical care
0.938 0.062 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.936 0.064 0.000
M23 Internal derangement of knee
0.935 0.065 0.000
K55-K64 Other diseases of intestines
0.935 0.065 0.000
M05-M14 Inflammatory polyarthropathies
0.934 0.066 0.000
Chapter V Mental and behavioural disorders
0.933 0.067 0.000
K90 Intestinal malabsorption
0.932 0.068 0.000
S80-S89 Injuries to the knee and lower leg
0.932 0.068 0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.931 0.069 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.930 0.070 0.000
S20-S29 Injuries to the thorax
0.926 0.074 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.925 0.075 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.923 0.077 0.000
S60-S69 Injuries to the wrist and hand
0.923 0.077 0.000
J98 Other respiratory disorders
0.919 0.081 0.000
K57 Diverticular disease of intestine
0.914 0.086 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.908 0.092 0.000
K92 Other diseases of digestive system
0.905 0.095 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.902 0.098 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.902 0.098 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.902 0.098 0.000
M45-M49 Spondylopathies
0.898 0.102 0.000
M50-M54 Other dorsopathies
0.898 0.102 0.000
D00-D09 In situ neoplasms
0.894 0.106 0.000
K90.0 Coeliac disease
0.894 0.106 0.000
M13 Other arthritis
0.892 0.108 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.889 0.111 0.000
K70-K77 Diseases of liver
0.883 0.117 0.000
J98.1 Pulmonary collapse
0.881 0.119 0.000
Z50 Care involving use of rehabilitation procedures
0.881 0.119 0.000
S00 Superficial injury of head
0.880 0.120 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.879 0.121 0.000
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess
0.876 0.124 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.875 0.125 0.000
Z74 Problems related to care-provider dependency
0.870 0.130 0.000
S01 Open wound of head
0.869 0.131 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.868 0.132 0.000
Z60 Problems related to social environment
0.867 0.133 0.000
Z51.1 Chemotherapy session for neoplasm
0.866 0.134 0.000
Chapter XX External causes of morbidity and mortality
0.866 0.134 0.000
M13.9 Arthritis, unspecified
0.862 0.138 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.862 0.138 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.861 0.139 0.000
D24 Benign neoplasm of breast
0.860 0.140 0.000
J40-J47 Chronic lower respiratory diseases
0.856 0.144 0.000
Z72 Problems related to lifestyle
0.850 0.150 0.000
M80-M85 Disorders of bone density and structure
0.848 0.152 0.000
S02 Fracture of skull and facial bones
0.848 0.152 0.000
D32 Benign neoplasm of meninges
0.848 0.152 0.000
K35-K38 Diseases of appendix
0.848 0.152 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.844 0.155 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.843 0.157 0.000
J90-J94 Other diseases of pleura
0.841 0.159 0.000
M35 Other systemic involvement of connective tissue
0.840 0.160 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.839 0.161 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.838 0.162 0.000
D34 Benign neoplasm of thyroid gland
0.833 0.167 0.000
L72.1 Trichilemmal cyst
0.831 0.169 0.000
J00-J06 Acute upper respiratory infections
0.831 0.169 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.831 0.169 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.830 0.170 0.000
S81 Open wound of lower leg
0.829 0.171 0.000
M15-M19 Arthrosis
0.827 0.173 0.000
Chapter VII Diseases of the eye and adnexa
0.827 0.173 0.000
M50 Cervical disk disorders
0.823 0.177 0.000
Z60.2 Living alone
0.822 0.178 0.000
G20-G26 Extrapyramidal and movement disorders
0.820 0.180 0.000
S06 Intracranial injury
0.819 0.180 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.818 0.182 0.000
L71 Rosacea
0.817 0.183 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.814 0.186 0.000
K63 Other diseases of intestine
0.814 0.186 0.000
L60 Nail disorders
0.813 0.187 0.000
D12.3 Transverse colon
0.812 0.188 0.000
K92.2 Gastro-intestinal haemorrhage, unspecified
0.811 0.189 0.000
D12.8 Rectum
0.808 0.191 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.807 0.193 0.000
Z46 Fitting and adjustment of other devices
0.807 0.193 0.000
Z74.0 Reduced mobility
0.805 0.195 0.000
Z72.0 Tobacco use
0.805 0.195 0.000
Z48 Other surgical follow-up care
0.804 0.196 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.802 0.198 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.801 0.199 0.000
K50-K52 Noninfective enteritis and colitis
0.800 0.200 0.000
Chapter I Certain infectious and parasitic diseases
0.799 0.201 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.799 0.201 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.798 0.202 0.000
G90-G99 Other disorders of the nervous system
0.797 0.203 0.000
J60-J70 Lung diseases due to external agents
0.797 0.203 0.000
L40-L45 Papulosquamous disorders
0.796 0.204 0.000
R20 Disturbances of skin sensation
0.795 0.205 0.000
C79 Secondary malignant neoplasm of other sites
0.792 0.208 0.000
Z43 Attention to artificial openings
0.790 0.210 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.788 0.212 0.000
D17.6 Benign lipomatous neoplasm of spermatic cord
0.787 0.213 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.786 0.213 0.000
C78.7 Secondary malignant neoplasm of liver
0.786 0.213 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.786 0.214 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.786 0.214 0.000
M40-M43 Deforming dorsopathies
0.785 0.215 0.000
K85 Acute pancreatitis
0.784 0.216 0.000
K80.1 Calculus of gallbladder with other cholecystitis
0.784 0.216 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.784 0.216 0.000
M47 Spondylosis
0.783 0.217 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.783 0.217 0.000
M13.98 Arthritis, unspecified (Other)
0.782 0.218 0.000
D12.9 Anus and anal canal
0.781 0.219 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.780 0.220 0.000
Z51.8 Other specified medical care
0.778 0.222 0.000
L20-L30 Dermatitis and eczema
0.778 0.222 0.000
D22 Melanocytic naevi
0.775 0.225 0.000
R50-R69 General symptoms and signs
0.771 0.229 0.000
Chapter XXII Codes for special purposes
0.770 0.230 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.769 0.231 0.000
S20 Superficial injury of thorax
0.769 0.231 0.000
D12.4 Descending colon
0.769 0.231 0.000
J98.4 Other disorders of lung
0.769 0.231 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.768 0.232 0.000
K70 Alcoholic liver disease
0.767 0.233 0.000
K80.4 Calculus of bile duct with cholecystitis
0.767 0.233 0.000
K82 Other diseases of gallbladder
0.765 0.235 0.000
M24 Other specific joint derangements
0.759 0.241 0.000
M91-M94 Chondropathies
0.759 0.241 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.759 0.241 0.000
F30-F39 Mood [affective] disorders
0.758 0.242 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.756 0.244 0.000
D18 Haemangioma and lymphangioma, any site
0.756 0.244 0.000
Z73 Problems related to life-management difficulty
0.756 0.244 0.000
Z51.0 Radiotherapy session
0.756 0.244 0.000
R25 Abnormal involuntary movements
0.755 0.245 0.000
G30-G32 Other degenerative diseases of the nervous system
0.754 0.246 0.000
S82 Fracture of lower leg, including ankle
0.753 0.247 0.000
S32 Fracture of lumbar spine and pelvis
0.753 0.247 0.000
S00.0 Superficial injury of scalp
0.751 0.249 0.000
K63.3 Ulcer of intestine
0.750 0.250 0.000
M51 Other intervertebral disk disorders
0.750 0.250 0.000
K13 Other diseases of lip and oral mucosa
0.749 0.251 0.000
M65-M68 Disorders of synovium and tendon
0.748 0.252 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.748 0.252 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.747 0.253 0.000
M45 Ankylosing spondylitis
0.747 0.253 0.000
S40-S49 Injuries to the shoulder and upper arm
0.746 0.253 0.000
M23.4 Loose body in knee
0.746 0.254 0.000
Z41 Procedures for purposes other than remedying health state
0.746 0.254 0.000
K92.1 Melaena
0.745 0.255 0.000
S22.4 Multiple fractures of ribs
0.744 0.256 0.000
S90-S99 Injuries to the ankle and foot
0.742 0.257 0.000
K59 Other functional intestinal disorders
0.742 0.258 0.000
K35 Acute appendicitis
0.742 0.258 0.000
Z63 Other problems related to primary support group, including family circumstances
0.741 0.258 0.000
D32.0 Cerebral meninges
0.741 0.259 0.000
D05 Carcinoma in situ of breast
0.740 0.260 0.000
R23 Other skin changes
0.739 0.260 0.000
F10.0 Acute intoxication
0.739 0.261 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.738 0.262 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.738 0.262 0.000
G57 Mononeuropathies of lower limb
0.738 0.262 0.000
S89 Other and unspecified injuries of lower leg
0.738 0.262 0.000
K57.3 Diverticular disease of large intestine without perforation or abscess
0.737 0.263 0.000
S01.5 Open wound of lip and oral cavity
0.736 0.264 0.000
R30-R39 Symptoms and signs involving the urinary system
0.735 0.265 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.735 0.265 0.000
F99-F99 Unspecified mental disorder
0.734 0.266 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.734 0.266 0.000
T93 Sequelae of injuries of lower limb
0.733 0.267 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.733 0.267 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.732 0.268 0.000
Z49 Care involving dialysis
0.731 0.269 0.000
J43 Emphysema
0.731 0.269 0.000
S00.8 Superficial injury of other parts of head
0.730 0.270 0.000
R20.2 Paraesthesia of skin
0.729 0.271 0.000
A00-A09 Intestinal infectious diseases
0.728 0.272 0.000
M50.1 Cervical disk disorder with radiculopathy
0.727 0.273 0.000
C15-C26 Malignant neoplasms of digestive organs
0.727 0.273 0.000
L71.9 Rosacea, unspecified
0.726 0.274 0.000
Z51.3 Blood transfusion without reported diagnosis
0.726 0.274 0.000
Z50.8 Care involving use of rehabilitation procedures
0.726 0.274 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.724 0.275 0.000
K57.1 Diverticular disease of small intestine without perforation or abscess
0.723 0.277 0.000
S61 Open wound of wrist and hand
0.721 0.279 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.721 0.279 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.721 0.279 0.000
D36 Benign neoplasm of other and unspecified sites
0.720 0.280 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.720 0.280 0.000
L60.0 Ingrowing nail
0.719 0.281 0.000
W00-W19 Falls
0.718 0.282 0.000
Z75 Problems related to medical facilities and other health care
0.718 0.282 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.718 0.282 0.000
M23.8 Other internal derangements of knee
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.717 0.283 0.000
D27 Benign neoplasm of ovary
0.717 0.283 0.000
S50-S59 Injuries to the elbow and forearm
0.717 0.283 0.000
S62 Fracture at wrist and hand level
0.717 0.283 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.716 0.283 0.000
M60-M63 Disorders of muscles
0.716 0.283 0.000
M00-M03 Infectious arthropathies
0.716 0.283 0.000
D03 Melanoma in situ
0.716 0.284 0.000
S27 Injury of other and unspecified intrathoracic organs
0.716 0.284 0.000
K57.2 Diverticular disease of large intestine with perforation and abscess
0.716 0.284 0.000
C60-C63 Malignant neoplasms of male genital organs
0.715 0.285 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.715 0.285 0.000
D31 Benign neoplasm of eye and adnexa
0.715 0.285 0.000
D30 Benign neoplasm of urinary organs
0.715 0.285 0.000
D29 Benign neoplasm of male genital organs
0.715 0.285 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.715 0.285 0.000
D26 Other benign neoplasms of uterus
0.715 0.285 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.715 0.285 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.715 0.285 0.000
D19 Benign neoplasm of mesothelial tissue
0.715 0.285 0.000
D16 Benign neoplasm of bone and articular cartilage
0.715 0.285 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.715 0.285 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.715 0.285 0.000
D11 Benign neoplasm of major salivary glands
0.715 0.285 0.000
D10 Benign neoplasm of mouth and pharynx
0.715 0.285 0.000
M86-M90 Other osteopathies
0.714 0.286 0.000
R56 Convulsions, not elsewhere classified
0.713 0.287 0.000
S02.1 Fracture of base of skull
0.712 0.288 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.709 0.291 0.000
R51 Headache
0.709 0.291 0.000
D12.0 Caecum
0.707 0.292 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.707 0.293 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.707 0.293 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.707 0.293 0.000
S01.9 Open wound of head, part unspecified
0.706 0.294 0.000
S69 Other and unspecified injuries of wrist and hand
0.706 0.294 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.706 0.294 0.000
M50.0 Cervical disk disorder with myelopathy
0.705 0.295 0.000
M18 Arthrosis of first carpometacarpal joint
0.705 0.295 0.000
M35.0 Sicca syndrome [Sjogren]
0.705 0.295 0.000
S08 Traumatic amputation of part of head
0.704 0.295 0.000
S07 Crushing injury of head
0.704 0.295 0.000
S05 Injury of eye and orbit
0.704 0.295 0.000
S04 Injury of cranial nerves
0.704 0.295 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.704 0.295 0.000
F60-F69 Disorders of adult personality and behaviour
0.704 0.296 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.704 0.296 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.703 0.297 0.000
R45 Symptoms and signs involving emotional state
0.702 0.298 0.000
Z54 Convalescence
0.702 0.298 0.000
Z52 Donors of organs and tissues
0.702 0.298 0.000
Z44 Fitting and adjustment of external prosthetic device
0.702 0.298 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.702 0.298 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.701 0.299 0.000
M47.8 Other spondylosis
0.701 0.299 0.000
K75 Other inflammatory liver diseases
0.701 0.299 0.000
Chapter VIII Diseases of the ear and mastoid process
0.699 0.301 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.698 0.301 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.698 0.301 0.000
G20 Parkinson's disease
0.698 0.302 0.000
G70-G73 Diseases of myoneural junction and muscle
0.697 0.303 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.697 0.303 0.000
L10-L14 Bullous disorders
0.697 0.303 0.000
S60 Superficial injury of wrist and hand
0.696 0.304 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.696 0.304 0.000
M22 Disorders of patella
0.696 0.304 0.000
K50 Crohn's disease [regional enteritis]
0.696 0.304 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.695 0.305 0.000
S22.40 Multiple fractures of ribs (closed)
0.695 0.305 0.000
Z50.2 Alcohol rehabilitation
0.694 0.306 0.000
J09-J18 Influenza and pneumonia
0.694 0.306 0.000
J47 Bronchiectasis
0.693 0.307 0.000
K74 Fibrosis and cirrhosis of liver
0.692 0.308 0.000
Z45 Adjustment and management of implanted device
0.691 0.309 0.000
C85.1 B-cell lymphoma, unspecified
0.691 0.309 0.000
D22.5 Melanocytic naevi of trunk
0.691 0.309 0.000
R26 Abnormalities of gait and mobility
0.691 0.309 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.690 0.310 0.000
M34 Systemic sclerosis
0.690 0.310 0.000
M33 Dermatopolymyositis
0.690 0.310 0.000
M32 Systemic lupus erythematosus
0.690 0.310 0.000
M31 Other necrotising vasculopathies
0.690 0.310 0.000
M30 Polyarteritis nodosa and related conditions
0.690 0.310 0.000
M21 Other acquired deformities of limbs
0.690 0.310 0.000
S09 Other and unspecified injuries of head
0.690 0.310 0.000
D17.7 Benign lipomatous neoplasm of other sites
0.690 0.310 0.000
D17.5 Benign lipomatous neoplasm of intra-abdominal organs
0.690 0.310 0.000
D17.4 Benign lipomatous neoplasm of intrathoracic organs
0.690 0.310 0.000
Z76 Persons encountering health services in other circumstances
0.688 0.312 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.688 0.312 0.000
K63.9 Disease of intestine, unspecified
0.687 0.313 0.000
C78.0 Secondary malignant neoplasm of lung
0.687 0.313 0.000
Z50.0 Cardiac rehabilitation
0.687 0.313 0.000
J93 Pneumothorax
0.687 0.313 0.000
J42 Unspecified chronic bronchitis
0.686 0.314 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.686 0.314 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.686 0.314 0.000
K80.2 Calculus of gallbladder without cholecystitis
0.686 0.314 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.685 0.315 0.000
T66-T78 Other and unspecified effects of external causes
0.685 0.315 0.000
M35.3 Polymyalgia rheumatica
0.685 0.315 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.685 0.315 0.000
K70.9 Alcoholic liver disease, unspecified
0.684 0.315 0.000
S81.8 Open wound of other parts of lower leg
0.684 0.316 0.000
J46 Status asthmaticus
0.684 0.316 0.000
M81 Osteoporosis without pathological fracture
0.683 0.317 0.000
K80.3 Calculus of bile duct with cholangitis
0.683 0.317 0.000
K80.8 Other cholelithiasis
0.683 0.317 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.683 0.317 0.000
M06 Other rheumatoid arthritis
0.683 0.317 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.682 0.318 0.000
J96 Respiratory failure, not elsewhere classified
0.682 0.318 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.681 0.319 0.000
D17.9 Benign lipomatous neoplasm, unspecified
0.680 0.320 0.000
S81.0 Open wound of knee
0.679 0.321 0.000
R21 Rash and other nonspecific skin eruption
0.679 0.321 0.000
J90 Pleural effusion, not elsewhere classified
0.678 0.322 0.000
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk
0.678 0.322 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.678 0.322 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.678 0.322 0.000
M53 Other dorsopathies, not elsewhere classified
0.677 0.322 0.000
J84 Other interstitial pulmonary diseases
0.677 0.322 0.000
L75 Apocrine sweat disorders
0.677 0.323 0.000
L74 Eccrine sweat disorders
0.677 0.323 0.000
L73 Other follicular disorders
0.677 0.323 0.000
L70 Acne
0.677 0.323 0.000
L68 Hypertrichosis
0.677 0.323 0.000
L67 Hair colour and hair shaft abnormalities
0.677 0.323 0.000
L66 Cicatricial alopecia [scarring hair loss]
0.677 0.323 0.000
L65 Other nonscarring hair loss
0.677 0.323 0.000
L64 Androgenic alopecia
0.677 0.323 0.000
L63 Alopecia areata
0.677 0.323 0.000
L62 Nail disorders in diseases classified elsewhere
0.677 0.323 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.677 0.323 0.000
S01.0 Open wound of scalp
0.677 0.323 0.000
K12 Stomatitis and related lesions
0.676 0.324 0.000
S64 Injury of nerves at wrist and hand level
0.676 0.324 0.000
K86 Other diseases of pancreas
0.675 0.325 0.000
J44 Other chronic obstructive pulmonary disease
0.675 0.325 0.000
T43.2 Other and unspecified antidepressants
0.675 0.325 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.675 0.325 0.000
C64-C68 Malignant neoplasms of urinary tract
0.674 0.326 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.674 0.326 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.674 0.326 0.000
M46 Other inflammatory spondylopathies
0.674 0.326 0.000
Z51.9 Medical care, unspecified
0.672 0.327 0.000
Z51.6 Desensitisation to allergens
0.672 0.327 0.000
F10.3 Withdrawal state
0.672 0.328 0.000
R56.8 Other and unspecified convulsions
0.672 0.328 0.000
L50-L54 Urticaria and erythema
0.672 0.328 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.671 0.328 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.671 0.329 0.000
D12.1 Appendix
0.671 0.329 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.671 0.329 0.000
L40 Psoriasis
0.671 0.329 0.000
M23.9 Internal derangement of knee, unspecified
0.670 0.330 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.670 0.330 0.000
M23.5 Chronic instability of knee
0.670 0.330 0.000
M23.1 Discoid meniscus (congenital)
0.670 0.330 0.000
M23.0 Cystic meniscus
0.670 0.330 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.670 0.330 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.670 0.330 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.670 0.330 0.000
J02 Acute pharyngitis
0.670 0.330 0.000
M14 Arthropathies in other diseases classified elsewhere
0.670 0.330 0.000
M12 Other specific arthropathies
0.670 0.330 0.000
M11 Other crystal arthropathies
0.670 0.330 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.670 0.330 0.000
M08 Juvenile arthritis
0.670 0.330 0.000
M07 Psoriatic and enteropathic arthropathies
0.670 0.330 0.000
M05 Seropositive rheumatoid arthritis
0.670 0.330 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.669 0.331 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.669 0.331 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.669 0.331 0.000
F80-F89 Disorders of psychological development
0.669 0.331 0.000
F70-F79 Mental retardation
0.669 0.331 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.669 0.331 0.000
K90.9 Intestinal malabsorption, unspecified
0.668 0.332 0.000
K90.8 Other intestinal malabsorption
0.668 0.332 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.668 0.332 0.000
K90.3 Pancreatic steatorrhoea
0.668 0.332 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.668 0.332 0.000
K90.1 Tropical sprue
0.668 0.332 0.000
S88 Traumatic amputation of lower leg
0.668 0.332 0.000
S87 Crushing injury of lower leg
0.668 0.332 0.000
S86 Injury of muscle and tendon at lower leg level
0.668 0.332 0.000
S85 Injury of blood vessels at lower leg level
0.668 0.332 0.000
S84 Injury of nerves at lower leg level
0.668 0.332 0.000
S80 Superficial injury of lower leg
0.668 0.332 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.668 0.332 0.000
S02.2 Fracture of nasal bones
0.667 0.333 0.000
C18 Malignant neoplasm of colon
0.667 0.333 0.000
Z65 Problems related to other psychosocial circumstances
0.667 0.333 0.000
Z64 Problems related to certain psychosocial circumstances
0.667 0.333 0.000
Z62 Other problems related to upbringing
0.667 0.333 0.000
Z61 Problems related to negative life events in childhood
0.667 0.333 0.000
Z59 Problems related to housing and economic circumstances
0.667 0.333 0.000
Z58 Problems related to physical environment
0.667 0.333 0.000
Z56 Problems related to employment and unemployment
0.667 0.333 0.000
Z55 Problems related to education and literacy
0.667 0.333 0.000
S00.1 Contusion of eyelid and periocular area
0.667 0.333 0.000
C80 Malignant neoplasm without specification of site
0.667 0.333 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.666 0.334 0.000
L08 Other local infections of skin and subcutaneous tissue
0.664 0.336 0.000
J03 Acute tonsillitis
0.664 0.336 0.000
S29 Other and unspecified injuries of thorax
0.664 0.336 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.664 0.336 0.000
S26 Injury of heart
0.664 0.336 0.000
S25 Injury of blood vessels of thorax
0.664 0.336 0.000
S24 Injury of nerves and spinal cord at thorax level
0.664 0.336 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.664 0.336 0.000
S21 Open wound of thorax
0.664 0.336 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.663 0.337 0.000
G58 Other mononeuropathies
0.663 0.337 0.000
G54 Nerve root and plexus disorders
0.663 0.337 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.663 0.337 0.000
G52 Disorders of other cranial nerves
0.663 0.337 0.000
H53-H54 Visual disturbances and blindness
0.663 0.337 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.663 0.337 0.000
S32.0 Fracture of lumbar vertebra
0.663 0.337 0.000
D06 Carcinoma in situ of cervix uteri
0.662 0.338 0.000
M23.3 Other meniscus derangements
0.662 0.338 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.662 0.338 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.662 0.338 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.662 0.338 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.662 0.338 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.662 0.338 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.662 0.338 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.662 0.338 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.662 0.338 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.662 0.338 0.000
T36 Poisoning by systemic antibiotics
0.662 0.338 0.000
S67 Crushing injury of wrist and hand
0.662 0.338 0.000
S65 Injury of blood vessels at wrist and hand level
0.662 0.338 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.662 0.338 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.661 0.339 0.000
G50 Disorders of trigeminal nerve
0.660 0.339 0.000
J69 Pneumonitis due to solids and liquids
0.659 0.341 0.000
S70-S79 Injuries to the hip and thigh
0.659 0.341 0.000
J98.9 Respiratory disorder, unspecified
0.659 0.341 0.000
J98.8 Other specified respiratory disorders
0.659 0.341 0.000
J98.6 Disorders of diaphragm
0.659 0.341 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.659 0.341 0.000
J98.3 Compensatory emphysema
0.659 0.341 0.000
J98.2 Interstitial emphysema
0.659 0.341 0.000
R39 Other symptoms and signs involving the urinary system
0.658 0.342 0.000
S20.8 Superficial injuries of other and unspecified parts of thorax
0.657 0.342 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.657 0.343 0.000
K92.0 Haematemesis
0.656 0.344 0.000
D13.1 Stomach
0.656 0.344 0.000
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess
0.655 0.344 0.000
K57.5 Diverticular disease of both small and large intestine without perforation or abscess
0.655 0.344 0.000
K57.4 Diverticular disease of both small and large intestine with perforation and abscess
0.655 0.344 0.000
K57.0 Diverticular disease of small intestine with perforation and abscess
0.655 0.344 0.000
R27 Other lack of coordination
0.655 0.345 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.654 0.346 0.000
K58 Irritable bowel syndrome
0.654 0.346 0.000
Z46.8 Fitting and adjustment of other specified devices
0.654 0.346 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.653 0.347 0.000
Z22 Carrier of infectious disease
0.653 0.347 0.000
Z50.5 Speech therapy
0.652 0.348 0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere
0.651 0.349 0.000
G55.0 Nerve root and plexus compressions in neoplastic disease
0.651 0.349 0.000
Z57 Occupational exposure to risk-factors
0.651 0.349 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.650 0.350 0.000
R40 Somnolence, stupor and coma
0.649 0.351 0.000
K92.9 Disease of digestive system, unspecified
0.649 0.351 0.000
K92.8 Other specified diseases of digestive system
0.649 0.351 0.000
R47-R49 Symptoms and signs involving speech and voice
0.648 0.351 0.000
S06.5 Traumatic subdural haemorrhage
0.648 0.352 0.000
Z48.0 Attention to surgical dressings and sutures
0.648 0.352 0.000
K35.0 Acute appendicitis with generalised peritonitis
0.647 0.352 0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular
0.647 0.353 0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.647 0.353 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.647 0.353 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.647 0.353 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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