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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs116527709
log Bayes Factor = 14.7969
Chromosome 1   position 87,398,673  (GRCh37) Explore rs116527709 on Ensembl!
Variant rs116527709 is part of Cluster X0072

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
0.998 0.002 0.000
Chapter VII Diseases of the eye and adnexa
0.994 0.006 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.992 0.008 0.000
Chapter XI Diseases of the digestive system
0.991 0.009 0.000
Chapter IX Diseases of the circulatory system
0.991 0.009 0.000
Chapter XIV Diseases of the genitourinary system
0.990 0.010 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.988 0.012 0.000
S00-S09 Injuries to the head
0.987 0.013 0.000
M05-M14 Inflammatory polyarthropathies
0.985 0.015 0.000
N30-N39 Other diseases of urinary system
0.981 0.019 0.000
N39 Other disorders of urinary system
0.980 0.020 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.980 0.020 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.976 0.024 0.000
M06 Other rheumatoid arthritis
0.973 0.027 0.000
S01 Open wound of head
0.972 0.028 0.000
N39.3 Stress incontinence
0.972 0.028 0.000
H30-H36 Disorders of choroid and retina
0.971 0.029 0.000
S60-S69 Injuries to the wrist and hand
0.969 0.031 0.000
K22 Other diseases of oesophagus
0.968 0.032 0.000
I60-I69 Cerebrovascular diseases
0.967 0.033 0.000
M06.9 Rheumatoid arthritis, unspecified
0.963 0.037 0.000
B95-B98 Bacterial, viral and other infectious agents
0.961 0.039 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.956 0.044 0.000
Chapter VI Diseases of the nervous system
0.953 0.047 0.000
K30 Dyspepsia
0.947 0.053 0.000
H35 Other retinal disorders
0.946 0.054 0.000
M20-M25 Other joint disorders
0.940 0.060 0.000
B07 Viral warts
0.939 0.061 0.000
S80-S89 Injuries to the knee and lower leg
0.936 0.064 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.932 0.068 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.931 0.069 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.927 0.073 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.925 0.075 0.000
S01.5 Open wound of lip and oral cavity
0.922 0.078 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.920 0.080 0.000
N39.0 Urinary tract infection, site not specified
0.914 0.086 0.000
K22.7 Barrett's oesophagus
0.912 0.088 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.910 0.090 0.000
H35.8 Other specified retinal disorders
0.908 0.092 0.000
S01.0 Open wound of scalp
0.905 0.095 0.000
M50-M54 Other dorsopathies
0.900 0.100 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.890 0.110 0.000
S62 Fracture at wrist and hand level
0.887 0.113 0.000
M80-M85 Disorders of bone density and structure
0.887 0.113 0.000
M70-M79 Other soft tissue disorders
0.886 0.114 0.000
M20 Acquired deformities of fingers and toes
0.886 0.114 0.000
M65-M68 Disorders of synovium and tendon
0.881 0.119 0.000
M45-M49 Spondylopathies
0.881 0.119 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.878 0.122 0.000
S09 Other and unspecified injuries of head
0.877 0.123 0.000
L40-L45 Papulosquamous disorders
0.877 0.123 0.000
N25-N29 Other disorders of kidney and ureter
0.876 0.124 0.000
I77 Other disorders of arteries and arterioles
0.873 0.127 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.873 0.127 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.872 0.128 0.000
K22.1 Ulcer of oesophagus
0.871 0.129 0.000
K26 Duodenal ulcer
0.865 0.135 0.000
I69 Sequelae of cerebrovascular disease
0.865 0.135 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.858 0.142 0.000
S82 Fracture of lower leg, including ankle
0.856 0.144 0.000
S50-S59 Injuries to the elbow and forearm
0.856 0.144 0.000
N00-N08 Glomerular diseases
0.854 0.146 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.854 0.146 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.852 0.148 0.000
Chapter XX External causes of morbidity and mortality
0.852 0.148 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.848 0.152 0.000
M20.4 Other hammer toe(s) (acquired)
0.845 0.155 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.844 0.156 0.000
N39.4 Other specified urinary incontinence
0.841 0.159 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.840 0.160 0.000
M54 Dorsalgia
0.839 0.161 0.000
H34 Retinal vascular occlusions
0.839 0.161 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.839 0.161 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.838 0.162 0.000
I30-I52 Other forms of heart disease
0.837 0.163 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.833 0.167 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.833 0.167 0.000
M25 Other joint disorders, not elsewhere classified
0.827 0.173 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.826 0.174 0.000
H53-H54 Visual disturbances and blindness
0.825 0.175 0.000
G90-G99 Other disorders of the nervous system
0.825 0.175 0.000
B35-B49 Mycoses
0.825 0.175 0.000
M54.5 Low back pain
0.822 0.178 0.000
S90-S99 Injuries to the ankle and foot
0.820 0.180 0.000
G20-G26 Extrapyramidal and movement disorders
0.819 0.181 0.000
H40-H42 Glaucoma
0.816 0.184 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.816 0.184 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.813 0.187 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.813 0.187 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.813 0.187 0.000
M86-M90 Other osteopathies
0.812 0.187 0.000
H36 Retinal disorders in diseases classified elsewhere
0.812 0.188 0.000
L05 Pilonidal cyst
0.810 0.190 0.000
K50-K52 Noninfective enteritis and colitis
0.808 0.192 0.000
M10 Gout
0.807 0.193 0.000
T93 Sequelae of injuries of lower limb
0.807 0.193 0.000
K29 Gastritis and duodenitis
0.806 0.194 0.000
B00 Herpesviral [herpes simplex] infections
0.806 0.194 0.000
K25 Gastric ulcer
0.802 0.198 0.000
M54.59 Low back pain (Site unspecified)
0.802 0.198 0.000
N17-N19 Renal failure
0.800 0.200 0.000
S01.8 Open wound of other parts of head
0.799 0.201 0.000
K70-K77 Diseases of liver
0.799 0.201 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.798 0.202 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.797 0.203 0.000
S62.6 Fracture of other finger
0.796 0.204 0.000
I63 Cerebral infarction
0.793 0.207 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.791 0.209 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.791 0.209 0.000
S64 Injury of nerves at wrist and hand level
0.790 0.209 0.000
M65 Synovitis and tenosynovitis
0.790 0.210 0.000
N10-N16 Renal tubulo-interstitial diseases
0.789 0.211 0.000
K40-K46 Hernia
0.788 0.212 0.000
I78 Diseases of capillaries
0.788 0.212 0.000
B02 Zoster [herpes zoster]
0.786 0.214 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.784 0.216 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.780 0.220 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.779 0.221 0.000
S70-S79 Injuries to the hip and thigh
0.779 0.221 0.000
H10-H13 Disorders of conjunctiva
0.774 0.225 0.000
S82.6 Fracture of lateral malleolus
0.774 0.226 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.774 0.226 0.000
I74 Arterial embolism and thrombosis
0.774 0.226 0.000
T43.2 Other and unspecified antidepressants
0.774 0.226 0.000
S01.7 Multiple open wounds of head
0.773 0.226 0.000
Chapter XXII Codes for special purposes
0.773 0.227 0.000
H35.2 Other proliferative retinopathy
0.773 0.227 0.000
A00-A09 Intestinal infectious diseases
0.773 0.227 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.773 0.227 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.772 0.228 0.000
K22.2 Oesophageal obstruction
0.769 0.231 0.000
K81 Cholecystitis
0.769 0.231 0.000
L50-L54 Urticaria and erythema
0.768 0.232 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.767 0.233 0.000
B15-B19 Viral hepatitis
0.766 0.234 0.000
H43-H45 Disorders of vitreous body and globe
0.766 0.234 0.000
K22.8 Other specified diseases of oesophagus
0.765 0.235 0.000
N30 Cystitis
0.761 0.239 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.761 0.239 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.761 0.239 0.000
I77.1 Stricture of artery
0.760 0.240 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.760 0.240 0.000
N20-N23 Urolithiasis
0.758 0.242 0.000
I73 Other peripheral vascular diseases
0.758 0.242 0.000
M79.1 Myalgia
0.758 0.242 0.000
M80 Osteoporosis with pathological fracture
0.757 0.243 0.000
H35.5 Hereditary retinal dystrophy
0.757 0.243 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.755 0.245 0.000
S60 Superficial injury of wrist and hand
0.751 0.249 0.000
S10-S19 Injuries to the neck
0.751 0.249 0.000
K86 Other diseases of pancreas
0.749 0.251 0.000
K29.8 Duodenitis
0.748 0.252 0.000
K44 Diaphragmatic hernia
0.747 0.253 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.746 0.254 0.000
S02 Fracture of skull and facial bones
0.745 0.255 0.000
L40 Psoriasis
0.743 0.257 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.743 0.257 0.000
I67 Other cerebrovascular diseases
0.742 0.257 0.000
M45 Ankylosing spondylitis
0.742 0.258 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.741 0.258 0.000
L08 Other local infections of skin and subcutaneous tissue
0.741 0.259 0.000
I72 Other aneurysm
0.741 0.259 0.000
M20.0 Deformity of finger(s)
0.741 0.259 0.000
M79.6 Pain in limb
0.740 0.260 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.740 0.260 0.000
I27 Other pulmonary heart diseases
0.739 0.261 0.000
T79-T79 Certain early complications of trauma
0.739 0.261 0.000
S89 Other and unspecified injuries of lower leg
0.738 0.261 0.000
S09.9 Unspecified injury of head
0.738 0.262 0.000
M91-M94 Chondropathies
0.737 0.263 0.000
H55-H59 Other disorders of eye and adnexa
0.737 0.263 0.000
S09.8 Other specified injuries of head
0.737 0.263 0.000
K35-K38 Diseases of appendix
0.736 0.264 0.000
L20-L30 Dermatitis and eczema
0.736 0.264 0.000
T92 Sequelae of injuries of upper limb
0.736 0.264 0.000
G40-G47 Episodic and paroxysmal disorders
0.734 0.266 0.000
K26.5 Chronic or unspecified with perforation
0.733 0.267 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.733 0.267 0.000
I62 Other nontraumatic intracranial haemorrhage
0.733 0.267 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.732 0.268 0.000
M07 Psoriatic and enteropathic arthropathies
0.732 0.268 0.000
S62.60 Fracture of other finger (closed)
0.731 0.269 0.000
L93 Lupus erythematosus
0.731 0.269 0.000
N04 Nephrotic syndrome
0.730 0.270 0.000
M11 Other crystal arthropathies
0.730 0.270 0.000
M06.0 Seronegative rheumatoid arthritis
0.730 0.270 0.000
M20.3 Other deformity of hallux (acquired)
0.730 0.270 0.000
S50 Superficial injury of forearm
0.726 0.274 0.000
K22.4 Dyskinesia of oesophagus
0.726 0.274 0.000
S68 Traumatic amputation of wrist and hand
0.725 0.275 0.000
N99-N99 Other disorders of the genitourinary system
0.725 0.275 0.000
M84 Disorders of continuity of bone
0.724 0.275 0.000
L85 Other epidermal thickening
0.724 0.276 0.000
G30-G32 Other degenerative diseases of the nervous system
0.724 0.276 0.000
S80 Superficial injury of lower leg
0.723 0.277 0.000
L43 Lichen planus
0.723 0.277 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.722 0.278 0.000
N39.9 Disorder of urinary system, unspecified
0.721 0.279 0.000
S06 Intracranial injury
0.719 0.280 0.000
T90 Sequelae of injuries of head
0.719 0.280 0.000
H18 Other disorders of cornea
0.719 0.281 0.000
M40-M43 Deforming dorsopathies
0.719 0.281 0.000
G82 Paraplegia and tetraplegia
0.718 0.282 0.000
K44.9 Diaphragmatic hernia without obstruction or gangrene
0.718 0.282 0.000
K26.0 Acute with haemorrhage
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
K27 Peptic ulcer, site unspecified
0.716 0.284 0.000
B99-B99 Other infectious diseases
0.716 0.284 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.716 0.284 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.716 0.284 0.000
B65-B83 Helminthiases
0.716 0.284 0.000
B50-B64 Protozoal diseases
0.716 0.284 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.716 0.284 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.716 0.284 0.000
A80-A89 Viral infections of the central nervous system
0.716 0.284 0.000
A75-A79 Rickettsioses
0.716 0.284 0.000
A70-A74 Other diseases caused by chlamydiae
0.716 0.284 0.000
A65-A69 Other spirochaetal diseases
0.716 0.284 0.000
A20-A28 Certain zoonotic bacterial diseases
0.716 0.284 0.000
A15-A19 Tuberculosis
0.716 0.284 0.000
S82.60 Fracture of lateral malleolus (closed)
0.716 0.284 0.000
S20-S29 Injuries to the thorax
0.715 0.285 0.000
I77.6 Arteritis, unspecified
0.715 0.285 0.000
L89 Decubitus ulcer
0.715 0.285 0.000
S40-S49 Injuries to the shoulder and upper arm
0.715 0.285 0.000
H34.8 Other retinal vascular occlusions
0.714 0.286 0.000
T91 Sequelae of injuries of neck and trunk
0.714 0.286 0.000
Q80-Q89 Other congenital malformations
0.713 0.287 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.713 0.287 0.000
H53 Visual disturbances
0.712 0.288 0.000
L10-L14 Bullous disorders
0.712 0.288 0.000
S82.5 Fracture of medial malleolus
0.711 0.289 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.711 0.289 0.000
G20 Parkinson's disease
0.711 0.289 0.000
I00-I02 Acute rheumatic fever
0.710 0.290 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.709 0.290 0.000
K28 Gastrojejunal ulcer
0.708 0.292 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.708 0.292 0.000
S08 Traumatic amputation of part of head
0.708 0.292 0.000
S07 Crushing injury of head
0.708 0.292 0.000
S05 Injury of eye and orbit
0.708 0.292 0.000
S04 Injury of cranial nerves
0.708 0.292 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.708 0.292 0.000
M05 Seropositive rheumatoid arthritis
0.707 0.293 0.000
M14 Arthropathies in other diseases classified elsewhere
0.706 0.293 0.000
M12 Other specific arthropathies
0.706 0.293 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.706 0.293 0.000
M08 Juvenile arthritis
0.706 0.293 0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
0.706 0.294 0.000
S69 Other and unspecified injuries of wrist and hand
0.705 0.295 0.000
I60 Subarachnoid haemorrhage
0.704 0.296 0.000
N37 Urethral disorders in diseases classified elsewhere
0.703 0.297 0.000
N34 Urethritis and urethral syndrome
0.703 0.297 0.000
N33 Bladder disorders in diseases classified elsewhere
0.703 0.297 0.000
N39.2 Orthostatic proteinuria, unspecified
0.703 0.297 0.000
N39.1 Persistent proteinuria, unspecified
0.703 0.297 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.703 0.297 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.703 0.297 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.703 0.297 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.703 0.297 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.703 0.297 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.703 0.297 0.000
T36 Poisoning by systemic antibiotics
0.703 0.297 0.000
S82.1 Fracture of upper end of tibia
0.702 0.298 0.000
M25.4 Effusion of joint
0.702 0.298 0.000
L05.9 Pilonidal cyst without abscess
0.701 0.299 0.000
N28.1 Cyst of kidney, acquired
0.701 0.299 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.700 0.300 0.000
B06 Rubella [German measles]
0.700 0.300 0.000
B05 Measles
0.700 0.300 0.000
B01 Varicella [chickenpox]
0.700 0.300 0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions
0.700 0.300 0.000
B04 Monkeypox
0.700 0.300 0.000
B03 Smallpox
0.700 0.300 0.000
M21 Other acquired deformities of limbs
0.700 0.300 0.000
H35.0 Background retinopathy and retinal vascular changes
0.699 0.301 0.000
H36.0 Diabetic retinopathy
0.698 0.302 0.000
M06.8 Other specified rheumatoid arthritis
0.697 0.302 0.000
M06.4 Inflammatory polyarthropathy
0.697 0.302 0.000
M06.3 Rheumatoid nodule
0.697 0.302 0.000
M06.2 Rheumatoid bursitis
0.697 0.302 0.000
M06.1 Adult-onset Still's disease
0.697 0.302 0.000
S01.4 Open wound of cheek and temporomandibular area
0.697 0.303 0.000
S01.3 Open wound of ear
0.697 0.303 0.000
S62.2 Fracture of first metacarpal bone
0.697 0.303 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.696 0.304 0.000
H31 Other disorders of choroid
0.696 0.304 0.000
H30 Chorioretinal inflammation
0.696 0.304 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.696 0.304 0.000
N19 Unspecified renal failure
0.696 0.304 0.000
K22.9 Disease of oesophagus, unspecified
0.696 0.304 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.696 0.304 0.000
S67 Crushing injury of wrist and hand
0.694 0.305 0.000
S65 Injury of blood vessels at wrist and hand level
0.694 0.305 0.000
S62.5 Fracture of thumb
0.694 0.306 0.000
K22.5 Diverticulum of oesophagus, acquired
0.694 0.306 0.000
K22.3 Perforation of oesophagus
0.694 0.306 0.000
K22.0 Achalasia of cardia
0.694 0.306 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.693 0.307 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.693 0.307 0.000
M54.57 Low back pain (Lumbosacral region)
0.693 0.307 0.000
M79.8 Other specified soft tissue disorders
0.693 0.307 0.000
N39.8 Other specified disorders of urinary system
0.692 0.308 0.000
M20.2 Hallux rigidus
0.692 0.308 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.690 0.310 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.690 0.310 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.690 0.310 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.690 0.310 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.690 0.310 0.000
K29.4 Chronic atrophic gastritis
0.690 0.310 0.000
H40 Glaucoma
0.689 0.311 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.689 0.311 0.000
S64.3 Injury of digital nerve of thumb
0.688 0.312 0.000
Chapter V Mental and behavioural disorders
0.688 0.312 0.000
M51 Other intervertebral disk disorders
0.688 0.312 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.688 0.312 0.000
M48 Other spondylopathies
0.687 0.313 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.687 0.313 0.000
Q60-Q64 Congenital malformations of the urinary system
0.687 0.313 0.000
G81 Hemiplegia
0.687 0.313 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.686 0.314 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.686 0.314 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.685 0.315 0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.685 0.315 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.684 0.316 0.000
I61 Intracerebral haemorrhage
0.684 0.316 0.000
B00.1 Herpesviral vesicular dermatitis
0.684 0.316 0.000
G70-G73 Diseases of myoneural junction and muscle
0.683 0.317 0.000
W00-W19 Falls
0.683 0.317 0.000
M79.18 Myalgia (Other)
0.682 0.318 0.000
M22 Disorders of patella
0.682 0.318 0.000
L98.8 Other specified disorders of skin and subcutaneous tissue
0.681 0.319 0.000
K81.9 Cholecystitis, unspecified
0.680 0.320 0.000
M85 Other disorders of bone density and structure
0.680 0.320 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.679 0.320 0.000
M10.9 Gout, unspecified
0.679 0.321 0.000
H35.9 Retinal disorder, unspecified
0.678 0.322 0.000
H35.7 Separation of retinal layers
0.678 0.322 0.000
H35.6 Retinal haemorrhage
0.678 0.322 0.000
H35.4 Peripheral retinal degeneration
0.678 0.322 0.000
H35.1 Retinopathy of prematurity
0.678 0.322 0.000
G95 Other diseases of spinal cord
0.677 0.323 0.000
N26 Unspecified contracted kidney
0.677 0.323 0.000
N73 Other female pelvic inflammatory diseases
0.677 0.323 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.676 0.324 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.676 0.324 0.000
L81 Other disorders of pigmentation
0.675 0.325 0.000
S63.6 Sprain and strain of finger(s)
0.675 0.325 0.000
T66-T78 Other and unspecified effects of external causes
0.675 0.325 0.000
G93 Other disorders of brain
0.675 0.325 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.674 0.326 0.000
M34 Systemic sclerosis
0.674 0.326 0.000
M33 Dermatopolymyositis
0.674 0.326 0.000
M32 Systemic lupus erythematosus
0.674 0.326 0.000
M30 Polyarteritis nodosa and related conditions
0.674 0.326 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.673 0.327 0.000
S82.4 Fracture of fibula alone
0.672 0.327 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.671 0.329 0.000
S88 Traumatic amputation of lower leg
0.671 0.329 0.000
S87 Crushing injury of lower leg
0.671 0.329 0.000
S86 Injury of muscle and tendon at lower leg level
0.671 0.329 0.000
S85 Injury of blood vessels at lower leg level
0.671 0.329 0.000
S84 Injury of nerves at lower leg level
0.671 0.329 0.000
G40 Epilepsy
0.671 0.329 0.000
S92 Fracture of foot, except ankle
0.670 0.329 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.670 0.330 0.000
I44 Atrioventricular and left bundle-branch block
0.670 0.330 0.000
M46 Other inflammatory spondylopathies
0.670 0.330 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.669 0.331 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.668 0.332 0.000
I78.0 Hereditary haemorrhagic telangiectasia
0.668 0.332 0.000
L04 Acute lymphadenitis
0.668 0.332 0.000
L01 Impetigo
0.668 0.332 0.000
L00 Staphylococcal scalded skin syndrome
0.668 0.332 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.668 0.332 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.668 0.332 0.000
L94 Other localised connective tissue disorders
0.668 0.332 0.000
L87 Transepidermal elimination disorders
0.668 0.332 0.000
L88 Pyoderma gangrenosum
0.668 0.332 0.000
L86 Keratoderma in diseases classified elsewhere
0.668 0.332 0.000
L83 Acanthosis nigricans
0.668 0.332 0.000
L80 Vitiligo
0.668 0.332 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.667 0.333 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.666 0.334 0.000
N30.2 Other chronic cystitis
0.666 0.334 0.000
N36 Other disorders of urethra
0.665 0.334 0.000
T93.2 Sequelae of other fractures of lower limb
0.665 0.334 0.000
S81 Open wound of lower leg
0.665 0.335 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.665 0.335 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.665 0.335 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.664 0.336 0.000
T42.4 Benzodiazepines
0.664 0.336 0.000
B37 Candidiasis
0.664 0.336 0.000
T98 Sequelae of other and unspecified effects of external causes
0.663 0.337 0.000
T95 Sequelae of burns, corrosions and frostbite
0.663 0.337 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.663 0.337 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.663 0.337 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.663 0.337 0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)
0.663 0.337 0.000
L91 Hypertrophic disorders of skin
0.663 0.337 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.663 0.337 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.662 0.338 0.000
T43.9 Psychotropic drug, unspecified
0.660 0.340 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.660 0.340 0.000
T43.6 Psychostimulants with abuse potential
0.660 0.340 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.660 0.340 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.660 0.340 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.660 0.340 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.660 0.340 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.659 0.341 0.000
S32 Fracture of lumbar spine and pelvis
0.659 0.341 0.000
H34.2 Other retinal artery occlusions
0.659 0.341 0.000
K50 Crohn's disease [regional enteritis]
0.659 0.341 0.000
A04 Other bacterial intestinal infections
0.659 0.341 0.000
M20.5 Other deformities of toe(s) (acquired)
0.658 0.342 0.000
I70 Atherosclerosis
0.658 0.342 0.000
N03 Chronic nephritic syndrome
0.657 0.343 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.657 0.343 0.000
M24 Other specific joint derangements
0.656 0.344 0.000
M25.8 Other specified joint disorders
0.656 0.344 0.000
K70 Alcoholic liver disease
0.656 0.344 0.000
I49 Other cardiac arrhythmias
0.656 0.344 0.000
S01.2 Open wound of nose
0.655 0.345 0.000
I47 Paroxysmal tachycardia
0.654 0.346 0.000
M77 Other enthesopathies
0.654 0.346 0.000
I31 Other diseases of pericardium
0.653 0.347 0.000
K74 Fibrosis and cirrhosis of liver
0.653 0.347 0.000
H53.0 Amblyopia ex anopsia
0.653 0.347 0.000
I20-I25 Ischaemic heart diseases
0.653 0.347 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.651 0.349 0.000
X60-X84 Intentional self-harm
0.651 0.349 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.650 0.350 0.000
B02.9 Zoster without complication
0.650 0.350 0.000
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.649 0.351 0.000
I71 Aortic aneurysm and dissection
0.649 0.351 0.000
S51 Open wound of forearm
0.648 0.352 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.648 0.352 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.648 0.352 0.000
M54.6 Pain in thoracic spine
0.647 0.353 0.000
M47 Spondylosis
0.647 0.353 0.000
M67 Other disorders of synovium and tendon
0.647 0.353 0.000
M53 Other dorsopathies, not elsewhere classified
0.645 0.355 0.000
K29.0 Acute haemorrhagic gastritis
0.645 0.355 0.000
K65-K67 Diseases of peritoneum
0.644 0.355 0.000
B35 Dermatophytosis
0.644 0.356 0.000
Q00-Q07 Congenital malformations of the nervous system
0.644 0.356 0.000
G80 Infantile cerebral palsy
0.643 0.356 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.643 0.357 0.000
L40.9 Psoriasis, unspecified
0.643 0.357 0.000
S01.9 Open wound of head, part unspecified
0.642 0.357 0.000
G83 Other paralytic syndromes
0.642 0.358 0.000
H18.5 Hereditary corneal dystrophies
0.642 0.358 0.000
K21 Gastro-oesophageal reflux disease
0.642 0.358 0.000
N04.9 Unspecified
0.642 0.358 0.000
H35.3 Degeneration of macula and posterior pole
0.641 0.359 0.000
S70 Superficial injury of hip and thigh
0.640 0.360 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.640 0.360 0.000
M87 Osteonecrosis
0.639 0.360 0.000
M25.5 Pain in joint
0.638 0.362 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.638 0.362 0.000
G91 Hydrocephalus
0.638 0.362 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.638 0.362 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.638 0.362 0.000
I46 Cardiac arrest
0.637 0.363 0.000
K26.4 Chronic or unspecified with haemorrhage
0.637 0.363 0.000
N20 Calculus of kidney and ureter
0.636 0.364 0.000
H40.9 Glaucoma, unspecified
0.636 0.364 0.000
K51 Ulcerative colitis
0.636 0.364 0.000
S62.8 Fracture of other and unspecified parts of wrist and hand
0.636 0.364 0.000
S62.7 Multiple fractures of fingers
0.636 0.364 0.000
S62.4 Multiple fractures of metacarpal bones
0.636 0.364 0.000
S62.1 Fracture of other carpal bone(s)
0.636 0.364 0.000
S62.0 Fracture of navicular [scaphoid] bone of hand
0.636 0.364 0.000
M83 Adult osteomalacia
0.636 0.364 0.000
M82 Osteoporosis in diseases classified elsewhere
0.636 0.364 0.000
M76 Enthesopathies of lower limb, excluding foot
0.635 0.364 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.635 0.364 0.000
M71 Other bursopathies
0.635 0.364 0.000
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.635 0.365 0.000
L84 Corns and callosities
0.635 0.365 0.000
Q50-Q56 Congenital malformations of genital organs
0.633 0.366 0.000
S50.9 Superficial injury of forearm, unspecified
0.633 0.367 0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck
0.633 0.367 0.000
N05 Unspecified nephritic syndrome
0.633 0.367 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.632 0.368 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.632 0.368 0.000
M66 Spontaneous rupture of synovium and tendon
0.632 0.368 0.000
M49 Spondylopathies in diseases classified elsewhere
0.631 0.368 0.000
S52 Fracture of forearm
0.630 0.370 0.000
I33 Acute and subacute endocarditis
0.630 0.370 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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