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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs116531279
log Bayes Factor = 19.1393
Chromosome 4   position 31,427,147  (GRCh37) Explore rs116531279 on Ensembl!
Variant rs116531279 is part of Cluster X0222

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
B95-B98 Bacterial, viral and other infectious agents
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Chapter VII Diseases of the eye and adnexa
0.997 0.003 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.997 0.003 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.993 0.007 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.988 0.012 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.987 0.013 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.982 0.018 0.000
H53-H54 Visual disturbances and blindness
0.980 0.020 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.977 0.023 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.977 0.023 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.976 0.024 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.967 0.033 0.000
J30-J39 Other diseases of upper respiratory tract
0.965 0.035 0.000
E70-E90 Metabolic disorders
0.964 0.036 0.000
H53 Visual disturbances
0.963 0.037 0.000
Y83.6 Removal of other organ (partial) (total)
0.963 0.037 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.962 0.038 0.000
Chapter IX Diseases of the circulatory system
0.957 0.043 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.956 0.044 0.000
E00-E07 Disorders of thyroid gland
0.955 0.045 0.000
Chapter XI Diseases of the digestive system
0.947 0.053 0.000
E65-E68 Obesity and other hyperalimentation
0.945 0.055 0.000
J40-J47 Chronic lower respiratory diseases
0.943 0.057 0.000
M20-M25 Other joint disorders
0.939 0.061 0.000
M65-M68 Disorders of synovium and tendon
0.935 0.065 0.000
S00-S09 Injuries to the head
0.932 0.068 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.930 0.070 0.000
B35-B49 Mycoses
0.925 0.075 0.000
J95-J99 Other diseases of the respiratory system
0.920 0.080 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.918 0.082 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.918 0.082 0.000
S70-S79 Injuries to the hip and thigh
0.915 0.085 0.000
W00-W19 Falls
0.914 0.086 0.000
R47-R49 Symptoms and signs involving speech and voice
0.914 0.086 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.911 0.089 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.911 0.089 0.000
J44 Other chronic obstructive pulmonary disease
0.911 0.089 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.911 0.089 0.000
O60-O75 Complications of labour and delivery
0.909 0.091 0.000
S20-S29 Injuries to the thorax
0.908 0.092 0.000
E66 Obesity
0.907 0.093 0.000
Chapter VI Diseases of the nervous system
0.907 0.093 0.000
K90-K93 Other diseases of the digestive system
0.901 0.099 0.000
I60-I69 Cerebrovascular diseases
0.901 0.099 0.000
J00-J06 Acute upper respiratory infections
0.899 0.101 0.000
R05 Cough
0.899 0.101 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.899 0.101 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.896 0.104 0.000
H53.9 Visual disturbance, unspecified
0.893 0.107 0.000
R00 Abnormalities of heart beat
0.892 0.108 0.000
J09-J18 Influenza and pneumonia
0.888 0.112 0.000
W20-W49 Exposure to inanimate mechanical forces
0.887 0.113 0.000
T66-T78 Other and unspecified effects of external causes
0.885 0.115 0.000
Chapter XXII Codes for special purposes
0.885 0.115 0.000
M24 Other specific joint derangements
0.885 0.115 0.000
Chapter XXI Factors influencing health status and contact with health services
0.883 0.117 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.877 0.123 0.000
M65 Synovitis and tenosynovitis
0.875 0.125 0.000
J33 Nasal polyp
0.875 0.125 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.872 0.128 0.000
K55-K64 Other diseases of intestines
0.868 0.132 0.000
J98 Other respiratory disorders
0.868 0.132 0.000
S60-S69 Injuries to the wrist and hand
0.862 0.138 0.000
H53.4 Visual field defects
0.861 0.139 0.000
H18 Other disorders of cornea
0.860 0.140 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.859 0.141 0.000
J33.0 Polyp of nasal cavity
0.857 0.143 0.000
Y40 Systemic antibiotics
0.850 0.149 0.000
I62 Other nontraumatic intracranial haemorrhage
0.850 0.150 0.000
H53.0 Amblyopia ex anopsia
0.849 0.151 0.000
O63 Long labour
0.849 0.151 0.000
B97.8 Other viral agents as the cause of diseases classified to other chapters
0.848 0.152 0.000
E66.8 Other obesity
0.848 0.152 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.848 0.152 0.000
R07 Pain in throat and chest
0.845 0.155 0.000
E20-E35 Disorders of other endocrine glands
0.844 0.156 0.000
J90-J94 Other diseases of pleura
0.842 0.158 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.840 0.160 0.000
M70-M79 Other soft tissue disorders
0.838 0.162 0.000
M23 Internal derangement of knee
0.836 0.164 0.000
H10-H13 Disorders of conjunctiva
0.836 0.164 0.000
T79-T79 Certain early complications of trauma
0.836 0.164 0.000
T90 Sequelae of injuries of head
0.835 0.165 0.000
W19 Unspecified fall
0.834 0.166 0.000
E87.7 Fluid overload
0.832 0.168 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.832 0.168 0.000
K59 Other functional intestinal disorders
0.832 0.168 0.000
B37 Candidiasis
0.830 0.170 0.000
H53.1 Subjective visual disturbances
0.830 0.170 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.830 0.170 0.000
E06 Thyroiditis
0.829 0.171 0.000
M05-M14 Inflammatory polyarthropathies
0.828 0.172 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.823 0.177 0.000
R07.3 Other chest pain
0.822 0.178 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.820 0.180 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.817 0.183 0.000
S06 Intracranial injury
0.817 0.183 0.000
Y83.9 Surgical procedure, unspecified
0.814 0.186 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.814 0.186 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.812 0.188 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.812 0.188 0.000
Y48 Anaesthetics and therapeutic gases
0.811 0.188 0.000
H40-H42 Glaucoma
0.811 0.189 0.000
J98.4 Other disorders of lung
0.810 0.190 0.000
E05.9 Thyrotoxicosis, unspecified
0.810 0.190 0.000
H43-H45 Disorders of vitreous body and globe
0.810 0.190 0.000
R47 Speech disturbances, not elsewhere classified
0.808 0.192 0.000
M24.1 Other articular cartilage disorders
0.804 0.196 0.000
E83 Disorders of mineral metabolism
0.804 0.196 0.000
K70-K77 Diseases of liver
0.804 0.196 0.000
K59.0 Constipation
0.804 0.196 0.000
I05-I09 Chronic rheumatic heart diseases
0.802 0.198 0.000
E04 Other non-toxic goitre
0.802 0.198 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.801 0.199 0.000
K55 Vascular disorders of intestine
0.801 0.199 0.000
K50-K52 Noninfective enteritis and colitis
0.798 0.202 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.798 0.202 0.000
J39 Other diseases of upper respiratory tract
0.798 0.202 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.795 0.205 0.000
K90 Intestinal malabsorption
0.795 0.205 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.792 0.208 0.000
J60-J70 Lung diseases due to external agents
0.791 0.208 0.000
J40 Bronchitis, not specified as acute or chronic
0.790 0.210 0.000
E66.9 Obesity, unspecified
0.790 0.210 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.790 0.210 0.000
H54 Blindness and low vision
0.788 0.212 0.000
J02 Acute pharyngitis
0.786 0.214 0.000
J03 Acute tonsillitis
0.785 0.215 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.784 0.216 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.783 0.216 0.000
R00.0 Tachycardia, unspecified
0.783 0.217 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.782 0.218 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.782 0.218 0.000
H25-H28 Disorders of lens
0.782 0.218 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.779 0.221 0.000
S09 Other and unspecified injuries of head
0.779 0.221 0.000
R02 Gangrene, not elsewhere classified
0.778 0.222 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.778 0.222 0.000
Chapter V Mental and behavioural disorders
0.776 0.224 0.000
I73 Other peripheral vascular diseases
0.776 0.224 0.000
T78 Adverse effects, not elsewhere classified
0.776 0.224 0.000
R49 Voice disturbances
0.775 0.224 0.000
J30 Vasomotor and allergic rhinitis
0.775 0.225 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.774 0.225 0.000
O66 Other obstructed labour
0.774 0.226 0.000
Y57 Other and unspecified drugs and medicaments
0.773 0.227 0.000
J43 Emphysema
0.773 0.227 0.000
M10 Gout
0.773 0.227 0.000
G90-G99 Other disorders of the nervous system
0.772 0.228 0.000
G20-G26 Extrapyramidal and movement disorders
0.771 0.229 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.771 0.229 0.000
M40-M43 Deforming dorsopathies
0.769 0.231 0.000
K35-K38 Diseases of appendix
0.769 0.231 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.768 0.232 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.767 0.233 0.000
V40-V49 Car occupant injured in transport accident
0.765 0.235 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.764 0.236 0.000
S68 Traumatic amputation of wrist and hand
0.764 0.236 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.764 0.236 0.000
M67 Other disorders of synovium and tendon
0.764 0.236 0.000
S00 Superficial injury of head
0.764 0.236 0.000
M23.5 Chronic instability of knee
0.763 0.237 0.000
W49 Exposure to other and unspecified inanimate mechanical forces
0.762 0.238 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.762 0.238 0.000
M21 Other acquired deformities of limbs
0.760 0.240 0.000
I85 Oesophageal varices
0.760 0.240 0.000
R80 Isolated proteinuria
0.759 0.241 0.000
O63.1 Prolonged second stage (of labour)
0.759 0.241 0.000
S20 Superficial injury of thorax
0.759 0.241 0.000
B02 Zoster [herpes zoster]
0.759 0.241 0.000
S72 Fracture of femur
0.758 0.242 0.000
S70 Superficial injury of hip and thigh
0.758 0.242 0.000
E86 Volume depletion
0.756 0.244 0.000
I63 Cerebral infarction
0.756 0.244 0.000
Y40.0 Penicillins
0.754 0.246 0.000
H18.8 Other specified disorders of cornea
0.753 0.247 0.000
E87.2 Acidosis
0.753 0.247 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.753 0.247 0.000
W19.9 Unspecified place
0.752 0.248 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.752 0.248 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.748 0.252 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.748 0.252 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.747 0.253 0.000
K50 Crohn's disease [regional enteritis]
0.746 0.254 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.746 0.254 0.000
Chapter VIII Diseases of the ear and mastoid process
0.745 0.255 0.000
I73.9 Peripheral vascular disease, unspecified
0.744 0.256 0.000
E87.3 Alkalosis
0.743 0.257 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.742 0.258 0.000
S27 Injury of other and unspecified intrathoracic organs
0.742 0.258 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.741 0.258 0.000
Y52 Agents primarily affecting the cardiovascular system
0.741 0.259 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.739 0.261 0.000
K55.2 Angiodysplasia of colon
0.738 0.262 0.000
E06.3 Autoimmune thyroiditis
0.738 0.262 0.000
M23.3 Other meniscus derangements
0.738 0.262 0.000
R25 Abnormal involuntary movements
0.737 0.263 0.000
E40-E46 Malnutrition
0.736 0.264 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.736 0.264 0.000
G30-G32 Other degenerative diseases of the nervous system
0.735 0.265 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.734 0.266 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.734 0.266 0.000
M10.9 Gout, unspecified
0.733 0.267 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.733 0.267 0.000
O63.0 Prolonged first stage (of labour)
0.733 0.267 0.000
M24.2 Disorder of ligament
0.732 0.268 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.732 0.268 0.000
B35 Dermatophytosis
0.732 0.268 0.000
K92 Other diseases of digestive system
0.732 0.268 0.000
H55-H59 Other disorders of eye and adnexa
0.730 0.269 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.730 0.270 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.730 0.270 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.729 0.271 0.000
B15-B19 Viral hepatitis
0.729 0.271 0.000
Z72 Problems related to lifestyle
0.728 0.272 0.000
T90.4 Sequelae of injury of eye and orbit
0.728 0.272 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.728 0.272 0.000
M75 Shoulder lesions
0.727 0.273 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.726 0.274 0.000
Z74 Problems related to care-provider dependency
0.726 0.274 0.000
Y83.3 Surgical operation with formation of external stoma
0.724 0.276 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.724 0.276 0.000
R07.0 Pain in throat
0.723 0.277 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.723 0.277 0.000
B49 Unspecified mycosis
0.722 0.278 0.000
M20 Acquired deformities of fingers and toes
0.721 0.279 0.000
J18 Pneumonia, organism unspecified
0.720 0.280 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.720 0.280 0.000
S79 Other and unspecified injuries of hip and thigh
0.720 0.280 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.719 0.281 0.000
V20-V29 Motorcycle rider injured in transport accident
0.719 0.281 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.719 0.281 0.000
O73 Retained placenta and membranes, without haemorrhage
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
B99-B99 Other infectious diseases
0.717 0.283 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.717 0.283 0.000
B65-B83 Helminthiases
0.717 0.283 0.000
B50-B64 Protozoal diseases
0.717 0.283 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.717 0.283 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.717 0.283 0.000
A80-A89 Viral infections of the central nervous system
0.717 0.283 0.000
A75-A79 Rickettsioses
0.717 0.283 0.000
A70-A74 Other diseases caused by chlamydiae
0.717 0.283 0.000
A65-A69 Other spirochaetal diseases
0.717 0.283 0.000
A20-A28 Certain zoonotic bacterial diseases
0.717 0.283 0.000
A15-A19 Tuberculosis
0.717 0.283 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.717 0.283 0.000
Y10-Y34 Event of undetermined intent
0.717 0.283 0.000
Y00-Y09 Assault
0.717 0.283 0.000
X85-X99 Assault
0.717 0.283 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.717 0.283 0.000
X50-X57 Overexertion, travel and privation
0.717 0.283 0.000
X30-X39 Exposure to forces of nature
0.717 0.283 0.000
X20-X29 Contact with venomous animals and plants
0.717 0.283 0.000
X10-X19 Contact with heat and hot substances
0.717 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.717 0.283 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.717 0.283 0.000
W75-W84 Other accidental threats to breathing
0.717 0.283 0.000
W65-W74 Accidental drowning and submersion
0.717 0.283 0.000
W50-W64 Exposure to animate mechanical forces
0.717 0.283 0.000
V98-V99 Other and unspecified transport accidents
0.717 0.283 0.000
V95-V97 Air and space transport accidents
0.717 0.283 0.000
V90-V94 Water transport accidents
0.717 0.283 0.000
V80-V89 Other land transport accidents
0.717 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.717 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.717 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.717 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.717 0.283 0.000
V01-V09 Pedestrian injured in transport accident
0.717 0.283 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.717 0.283 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
S10-S19 Injuries to the neck
0.716 0.284 0.000
V10-V19 Pedal cyclist injured in transport accident
0.715 0.285 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.715 0.285 0.000
G70-G73 Diseases of myoneural junction and muscle
0.715 0.285 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.714 0.286 0.000
W25 Contact with sharp glass
0.713 0.287 0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.713 0.287 0.000
M71 Other bursopathies
0.713 0.287 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.713 0.287 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.713 0.287 0.000
B91 Sequelae of poliomyelitis
0.712 0.288 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.712 0.288 0.000
R94 Abnormal results of function studies
0.711 0.289 0.000
H18.5 Hereditary corneal dystrophies
0.711 0.289 0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.711 0.289 0.000
M91-M94 Chondropathies
0.709 0.291 0.000
M60-M63 Disorders of muscles
0.709 0.291 0.000
M00-M03 Infectious arthropathies
0.709 0.291 0.000
Y48.3 Local anaesthetics
0.708 0.292 0.000
S90-S99 Injuries to the ankle and foot
0.708 0.292 0.000
I85.9 Oesophageal varices without bleeding
0.708 0.292 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.708 0.292 0.000
I30-I52 Other forms of heart disease
0.707 0.293 0.000
Chapter XIV Diseases of the genitourinary system
0.707 0.293 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.706 0.294 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.706 0.294 0.000
J38.3 Other diseases of vocal cords
0.706 0.294 0.000
R47.8 Other and unspecified speech disturbances
0.706 0.294 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.705 0.294 0.000
J34 Other disorders of nose and nasal sinuses
0.705 0.295 0.000
J02.9 Acute pharyngitis, unspecified
0.705 0.295 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.704 0.296 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.704 0.296 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.704 0.296 0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters
0.704 0.296 0.000
M10.99 Gout, unspecified (Site unspecified)
0.703 0.297 0.000
J03.9 Acute tonsillitis, unspecified
0.703 0.297 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.703 0.297 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.702 0.298 0.000
Q50-Q56 Congenital malformations of genital organs
0.701 0.299 0.000
H18.9 Disorder of cornea, unspecified
0.701 0.299 0.000
Y83.5 Amputation of limb(s)
0.701 0.299 0.000
Y83.0 Surgical operation with transplant of whole organ
0.701 0.299 0.000
I67 Other cerebrovascular diseases
0.701 0.299 0.000
S71 Open wound of hip and thigh
0.700 0.299 0.000
J38.7 Other diseases of larynx
0.700 0.300 0.000
W10 Fall on and from stairs and steps
0.700 0.300 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.700 0.300 0.000
S06.2 Diffuse brain injury
0.699 0.301 0.000
T68 Hypothermia
0.699 0.301 0.000
M23.8 Other internal derangements of knee
0.698 0.302 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.697 0.303 0.000
A30-A49 Other bacterial diseases
0.697 0.303 0.000
O00-O08 Pregnancy with abortive outcome
0.696 0.304 0.000
R29.6 Tendency to fall, not elsewhere classified
0.696 0.304 0.000
S50-S59 Injuries to the elbow and forearm
0.695 0.305 0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems
0.694 0.306 0.000
K50.9 Crohn's disease, unspecified
0.694 0.306 0.000
O85-O92 Complications predominantly related to the puerperium
0.694 0.306 0.000
J14 Pneumonia due to Haemophilus influenzae
0.694 0.306 0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)
0.693 0.306 0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.693 0.307 0.000
T92 Sequelae of injuries of upper limb
0.693 0.307 0.000
M45-M49 Spondylopathies
0.693 0.307 0.000
R23 Other skin changes
0.692 0.308 0.000
J10 Influenza due to identified influenza virus
0.692 0.308 0.000
E27 Other disorders of adrenal gland
0.692 0.308 0.000
J37 Chronic laryngitis and laryngotracheitis
0.692 0.308 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.691 0.308 0.000
E85 Amyloidosis
0.691 0.309 0.000
E84 Cystic fibrosis
0.691 0.309 0.000
E79 Disorders of purine and pyrimidine metabolism
0.691 0.309 0.000
E77 Disorders of glycoprotein metabolism
0.691 0.309 0.000
E76 Disorders of glycosaminoglycan metabolism
0.691 0.309 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.691 0.309 0.000
E74 Other disorders of carbohydrate metabolism
0.691 0.309 0.000
E73 Lactose intolerance
0.691 0.309 0.000
E72 Other disorders of amino-acid metabolism
0.691 0.309 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.691 0.309 0.000
E70 Disorders of aromatic amino-acid metabolism
0.691 0.309 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.691 0.309 0.000
O61 Failed induction of labour
0.691 0.309 0.000
H53.6 Night blindness
0.690 0.309 0.000
H53.5 Colour vision deficiencies
0.690 0.309 0.000
H53.3 Other disorders of binocular vision
0.690 0.309 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.690 0.310 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.690 0.310 0.000
W19.2 School, other institution and public administrative area
0.690 0.310 0.000
M86-M90 Other osteopathies
0.690 0.310 0.000
N17-N19 Renal failure
0.690 0.310 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.689 0.311 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.689 0.311 0.000
M65.3 Trigger finger
0.689 0.311 0.000
Y44 Agents primarily affecting blood constituents
0.689 0.311 0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.688 0.312 0.000
S01 Open wound of head
0.688 0.312 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.687 0.313 0.000
R00.1 Bradycardia, unspecified
0.687 0.313 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.687 0.313 0.000
I00-I02 Acute rheumatic fever
0.686 0.313 0.000
X60-X84 Intentional self-harm
0.686 0.314 0.000
Y59 Other and unspecified vaccines and biological substances
0.685 0.315 0.000
Y58 Bacterial vaccines
0.685 0.315 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.685 0.315 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.685 0.315 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.685 0.315 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.685 0.315 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.685 0.315 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.685 0.315 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.685 0.315 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.685 0.315 0.000
N10-N16 Renal tubulo-interstitial diseases
0.685 0.315 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.685 0.315 0.000
Z72.0 Tobacco use
0.685 0.315 0.000
H26 Other cataract
0.685 0.315 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.685 0.315 0.000
J93 Pneumothorax
0.685 0.315 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.685 0.315 0.000
E00 Congenital iodine-deficiency syndrome
0.685 0.315 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.685 0.315 0.000
E80.4 Gilbert's syndrome
0.684 0.316 0.000
R26 Abnormalities of gait and mobility
0.683 0.317 0.000
I80 Phlebitis and thrombophlebitis
0.682 0.318 0.000
T78.4 Allergy, unspecified
0.682 0.318 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.681 0.319 0.000
H54.0 Blindness, both eyes
0.681 0.319 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.680 0.320 0.000
T90.9 Sequelae of unspecified injury of head
0.680 0.320 0.000
H11 Other disorders of conjunctiva
0.680 0.320 0.000
R82 Other abnormal findings in urine
0.679 0.320 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.679 0.321 0.000
J32 Chronic sinusitis
0.679 0.321 0.000
S29 Other and unspecified injuries of thorax
0.679 0.321 0.000
O72 Postpartum haemorrhage
0.678 0.322 0.000
H40 Glaucoma
0.678 0.322 0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified
0.678 0.322 0.000
E67 Other hyperalimentation
0.677 0.323 0.000
E68 Sequelae of hyperalimentation
0.677 0.323 0.000
E65 Localised adiposity
0.677 0.323 0.000
M75.1 Rotator cuff syndrome
0.677 0.323 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.677 0.323 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.677 0.323 0.000
J91 Pleural effusion in conditions classified elsewhere
0.676 0.324 0.000
J41 Simple and mucopurulent chronic bronchitis
0.676 0.324 0.000
R49.0 Dysphonia
0.676 0.324 0.000
N17 Acute renal failure
0.676 0.324 0.000
J98.9 Respiratory disorder, unspecified
0.675 0.325 0.000
E23 Hypofunction and other disorders of pituitary gland
0.675 0.325 0.000
B07 Viral warts
0.674 0.326 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.673 0.326 0.000
M34 Systemic sclerosis
0.673 0.326 0.000
M33 Dermatopolymyositis
0.673 0.326 0.000
M32 Systemic lupus erythematosus
0.673 0.326 0.000
M30 Polyarteritis nodosa and related conditions
0.673 0.326 0.000
E88 Other metabolic disorders
0.673 0.327 0.000
W49.9 Unspecified place
0.673 0.327 0.000
H44 Disorders of globe
0.672 0.328 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.672 0.328 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.672 0.328 0.000
U88 Agent resistant to multiple antibiotics
0.671 0.329 0.000
E22 Hyperfunction of pituitary gland
0.671 0.329 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.671 0.329 0.000
B37.8 Candidiasis of other sites
0.671 0.329 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.670 0.330 0.000
M66 Spontaneous rupture of synovium and tendon
0.670 0.330 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.670 0.330 0.000
S09.9 Unspecified injury of head
0.669 0.331 0.000
O42 Premature rupture of membranes
0.669 0.331 0.000
E83.4 Disorders of magnesium metabolism
0.669 0.331 0.000
S08 Traumatic amputation of part of head
0.668 0.332 0.000
S07 Crushing injury of head
0.668 0.332 0.000
S05 Injury of eye and orbit
0.668 0.332 0.000
S04 Injury of cranial nerves
0.668 0.332 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.668 0.332 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.668 0.332 0.000
B37.3 Candidiasis of vulva and vagina
0.668 0.332 0.000
Y40.9 Systemic antibiotic, unspecified
0.668 0.332 0.000
S64 Injury of nerves at wrist and hand level
0.668 0.332 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.668 0.332 0.000
N17.9 Acute renal failure, unspecified
0.667 0.333 0.000
B37.0 Candidal stomatitis
0.667 0.333 0.000
J39.8 Other specified diseases of upper respiratory tract
0.666 0.334 0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified
0.665 0.335 0.000
M50-M54 Other dorsopathies
0.663 0.337 0.000
B48 Other mycoses, not elsewhere classified
0.663 0.337 0.000
B47 Mycetoma
0.663 0.337 0.000
B46 Zygomycosis
0.663 0.337 0.000
B45 Cryptococcosis
0.663 0.337 0.000
B44 Aspergillosis
0.663 0.337 0.000
B43 Chromomycosis and phaeomycotic abscess
0.663 0.337 0.000
B42 Sporotrichosis
0.663 0.337 0.000
B41 Paracoccidioidomycosis
0.663 0.337 0.000
B40 Blastomycosis
0.663 0.337 0.000
B39 Histoplasmosis
0.663 0.337 0.000
B38 Coccidioidomycosis
0.663 0.337 0.000
B36 Other superficial mycoses
0.663 0.337 0.000
J69 Pneumonitis due to solids and liquids
0.663 0.337 0.000
E04.2 Non-toxic multinodular goitre
0.662 0.338 0.000
H10 Conjunctivitis
0.661 0.339 0.000
K90.0 Coeliac disease
0.661 0.339 0.000
T93 Sequelae of injuries of lower limb
0.660 0.340 0.000
W29 Contact with other powered hand tools and household machinery
0.660 0.340 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.660 0.340 0.000
I61 Intracerebral haemorrhage
0.660 0.340 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.660 0.340 0.000
J96 Respiratory failure, not elsewhere classified
0.660 0.340 0.000
M31 Other necrotising vasculopathies
0.659 0.341 0.000
J42 Unspecified chronic bronchitis
0.659 0.341 0.000
K59.3 Megacolon, not elsewhere classified
0.659 0.341 0.000
B97.6 Parvovirus as the cause of diseases classified to other chapters
0.658 0.341 0.000
B97.5 Reovirus as the cause of diseases classified to other chapters
0.658 0.341 0.000
B97.4 Respiratory synctial virus as the cause of diseases classified to other chapters
0.658 0.341 0.000
B97.3 Retrovirus as the cause of diseases classified to other chapters
0.658 0.341 0.000
B97.2 Coronavirus as the cause of diseases classified to other chapters
0.658 0.341 0.000
B97.1 Enterovirus as the cause of diseases classified to other chapters
0.658 0.341 0.000
B97.0 Adenovirus as the cause of diseases classified to other chapters
0.658 0.341 0.000
S72.1 Pertrochanteric fracture
0.658 0.342 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.658 0.342 0.000
I60 Subarachnoid haemorrhage
0.658 0.342 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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