TreeWAS – Variant ID: rs116567155

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
# Top node	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
M20-M25 Other joint disorders	1.000	0.000
M25 Other joint disorders, not elsewhere classified	1.000	0.000
M15-M19 Arthrosis	0.996	0.004
M25.5 Pain in joint	0.995	0.005
M17 Gonarthrosis [arthrosis of knee]	0.992	0.008
Chapter XII Diseases of the skin and subcutaneous tissue	0.991	0.009
M65-M68 Disorders of synovium and tendon	0.991	0.009
M25.55 Pain in joint (Pelvic region and thigh)	0.982	0.018
M17.1 Other primary gonarthrosis	0.978	0.022
S60-S69 Injuries to the wrist and hand	0.975	0.025
M70-M79 Other soft tissue disorders	0.971	0.029
M45-M49 Spondylopathies	0.971	0.029
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.961	0.039
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.957	0.043
Chapter II Neoplasms	0.955	0.045
M25.56 Pain in joint (Lower leg)	0.953	0.047
M75 Shoulder lesions	0.952	0.048
M19 Other arthrosis	0.949	0.051
M86-M90 Other osteopathies	0.947	0.053
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.947	0.053
M67 Other disorders of synovium and tendon	0.946	0.054
D37-D48 Neoplasms of uncertain or unknown behaviour	0.946	0.054
S61 Open wound of wrist and hand	0.945	0.055
M65 Synovitis and tenosynovitis	0.945	0.055
D69 Purpura and other haemorrhagic conditions	0.944	0.056
M75.0 Adhesive capsulitis of shoulder	0.941	0.059
L00-L08 Infections of the skin and subcutaneous tissue	0.937	0.063
M25.7 Osteophyte	0.936	0.064
T36-T50 Poisoning by drugs, medicaments and biological substances	0.929	0.071
M17.9 Gonarthrosis, unspecified	0.927	0.073
D69.6 Thrombocytopenia, unspecified	0.925	0.075
S40-S49 Injuries to the shoulder and upper arm	0.925	0.075
L80-L99 Other disorders of the skin and subcutaneous tissue	0.913	0.087
Chapter VI Diseases of the nervous system	0.906	0.094
S61.0 Open wound of finger(s) without damage to nail	0.905	0.095
M67.8 Other specified disorders of synovium and tendon	0.898	0.102
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.893	0.107
M65.9 Synovitis and tenosynovitis, unspecified	0.889	0.111
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.889	0.111
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.888	0.112
M25.8 Other specified joint disorders	0.886	0.114
L60-L75 Disorders of skin appendages	0.884	0.116
D68 Other coagulation defects	0.884	0.116
M89 Other disorders of bone	0.882	0.118
M80-M85 Disorders of bone density and structure	0.881	0.119
M75.1 Rotator cuff syndrome	0.879	0.121
M48 Other spondylopathies	0.879	0.121
S80-S89 Injuries to the knee and lower leg	0.879	0.121
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.876	0.124
M19.9 Arthrosis, unspecified	0.875	0.125
S20-S29 Injuries to the thorax	0.872	0.128
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.871	0.129
L02 Cutaneous abscess, furuncle and carbuncle	0.863	0.137
M47 Spondylosis	0.862	0.138
C64-C68 Malignant neoplasms of urinary tract	0.857	0.143
M25.74 Osteophyte (Hand)	0.850	0.150
C90 Multiple myeloma and malignant plasma cell neoplasms	0.849	0.151
M19.0 Primary arthrosis of other joints	0.844	0.156
M24 Other specific joint derangements	0.844	0.156
S61.1 Open wound of finger(s) with damage to nail	0.843	0.157
M25.77 Osteophyte (Ankle and foot)	0.842	0.158
L03 Cellulitis	0.838	0.162
S43.0 Dislocation of shoulder joint	0.836	0.164
Q60-Q64 Congenital malformations of the urinary system	0.836	0.164
M25.57 Pain in joint (Ankle and foot)	0.834	0.166
M19.97 Arthrosis, unspecified (Ankle and foot)	0.833	0.167
M25.3 Other instability of joint	0.833	0.167
G90-G99 Other disorders of the nervous system	0.832	0.168
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.832	0.168
M25.6 Stiffness of joint, not elsewhere classified	0.827	0.172
M25.0 Haemarthrosis	0.826	0.174
L92 Granulomatous disorders of skin and subcutaneous tissue	0.825	0.175
M17.5 Other secondary gonarthrosis	0.824	0.176
L71 Rosacea	0.824	0.176
M21 Other acquired deformities of limbs	0.819	0.181
C90.0 Multiple myeloma	0.819	0.181
T46 Poisoning by agents primarily affecting the cardiovascular system	0.819	0.181
L81 Other disorders of pigmentation	0.818	0.182
M70 Soft tissue disorders related to use, overuse and pressure	0.817	0.183
Chapter XX External causes of morbidity and mortality	0.817	0.183
S64 Injury of nerves at wrist and hand level	0.816	0.183
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.814	0.186
M89.9 Disorder of bone, unspecified	0.809	0.191
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.806	0.194
M48.0 Spinal stenosis	0.804	0.196
L97 Ulcer of lower limb, not elsewhere classified	0.800	0.200
M23 Internal derangement of knee	0.798	0.202
S10-S19 Injuries to the neck	0.797	0.203
C50-C50 Malignant neoplasm of breast	0.795	0.205
T66-T78 Other and unspecified effects of external causes	0.792	0.208
G93 Other disorders of brain	0.791	0.209
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.790	0.210
M90 Osteopathies in diseases classified elsewhere	0.788	0.212
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.787	0.213
D37.4 Colon	0.783	0.217
S90-S99 Injuries to the ankle and foot	0.781	0.219
D45 Polycythaemia vera	0.779	0.221
Chapter IX Diseases of the circulatory system	0.778	0.222
M47.9 Spondylosis, unspecified	0.777	0.223
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.776	0.224
M46 Other inflammatory spondylopathies	0.772	0.228
M84 Disorders of continuity of bone	0.772	0.228
S60 Superficial injury of wrist and hand	0.769	0.231
W20-W49 Exposure to inanimate mechanical forces	0.769	0.231
G20-G26 Extrapyramidal and movement disorders	0.768	0.232
S43.1 Dislocation of acromioclavicular joint	0.767	0.233
M67.2 Synovial hypertrophy, not elsewhere classified	0.765	0.235
L91 Hypertrophic disorders of skin	0.765	0.235
L03.1 Cellulitis of other parts of limb	0.764	0.236
G70-G73 Diseases of myoneural junction and muscle	0.763	0.237
M05-M14 Inflammatory polyarthropathies	0.763	0.237
M49 Spondylopathies in diseases classified elsewhere	0.761	0.239
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.760	0.239
D69.4 Other primary thrombocytopenia	0.760	0.240
C81 Hodgkin's disease	0.759	0.240
M19.96 Arthrosis, unspecified-Lower leg	0.758	0.242
I25.8 Other forms of chronic ischaemic heart disease	0.757	0.243
I25 Chronic ischaemic heart disease	0.757	0.243
I20-I25 Ischaemic heart diseases	0.757	0.243
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.756	0.243
M30 Polyarteritis nodosa and related conditions	0.754	0.246
M88 Paget's disease of bone [osteitis deformans]	0.754	0.246
D68.5 Primary Thrombophilia	0.754	0.246
L71.9 Rosacea, unspecified	0.754	0.246
M19.93 Arthrosis, unspecified (Forearm)	0.752	0.248
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.751	0.249
C84 Peripheral and cutaneous T-cell lymphomas	0.751	0.249
L02.1 Cutaneous abscess, furuncle and carbuncle of neck	0.748	0.251
C64 Malignant neoplasm of kidney, except renal pelvis	0.748	0.252
M66 Spontaneous rupture of synovium and tendon	0.747	0.253
M24.2 Disorder of ligament	0.746	0.254
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)	0.746	0.254
D46 Myelodysplastic syndromes	0.745	0.255
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.743	0.257
M77 Other enthesopathies	0.743	0.257
M65.1 Other infective (teno)synovitis	0.740	0.260
Q20-Q28 Congenital malformations of the circulatory system	0.740	0.260
G00-G09 Inflammatory diseases of the central nervous system	0.739	0.260
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.739	0.261
T92 Sequelae of injuries of upper limb	0.739	0.261
L81.4 Other melanin hyperpigmentation	0.736	0.264
S65 Injury of blood vessels at wrist and hand level	0.735	0.265
M25.87 Other specified joint disorders (Ankle and foot)	0.735	0.265
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.733	0.267
M25.4 Effusion of joint	0.733	0.267
D68.6 Other Thrombophilia	0.731	0.269
Q38-Q45 Other congenital malformations of the digestive system	0.730	0.270
M25.76 Osteophyte (Lower leg)	0.730	0.270
D69.3 Idiopathic thrombocytopenic purpura	0.730	0.270
M91-M94 Chondropathies	0.730	0.270
D37.6 Liver, gallbladder and bile ducts	0.728	0.272
M60-M63 Disorders of muscles	0.728	0.272
T46.4 Angiotensin-converting-enzyme inhibitors	0.727	0.273
Q80-Q89 Other congenital malformations	0.727	0.273
T91 Sequelae of injuries of neck and trunk	0.726	0.274
M25.84 Other specified joint disorders (Hand)	0.725	0.275
D47.1 Chronic myeloproliferative disease	0.725	0.275
L73 Other follicular disorders	0.724	0.276
S70-S79 Injuries to the hip and thigh	0.723	0.277
M75.2 Bicipital tendinitis	0.722	0.277
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.722	0.278
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.722	0.278
D37.5 Rectum	0.722	0.278
M19.90 Arthrosis, unspecified (Multiple sites)	0.721	0.279
S66 Injury of muscle and tendon at wrist and hand level	0.721	0.279
M70.6 Trochanteric bursitis	0.721	0.279
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.720	0.280
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.719	0.281
M23.2 Derangement of meniscus due to old tear or injury	0.719	0.281
S80 Superficial injury of lower leg	0.718	0.282
M72 Fibroblastic disorders	0.718	0.282
L60 Nail disorders	0.717	0.282
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T20-T25 Burns and corrosions of external body surface, specified by site	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.717	0.283
M33 Dermatopolymyositis	0.717	0.283
M32 Systemic lupus erythematosus	0.717	0.283
M25.2 Flail joint	0.717	0.283
M25.1 Fistula of joint	0.717	0.283
G80-G83 Cerebral palsy and other paralytic syndromes	0.716	0.284
M65.4 Radial styloid tenosynovitis [de Quervain]	0.715	0.285
L85 Other epidermal thickening	0.715	0.285
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.715	0.285
T79-T79 Certain early complications of trauma	0.715	0.285
M15 Polyarthrosis	0.714	0.286
L05 Pilonidal cyst	0.714	0.286
M25.37 Other instability of joint (Ankle and foot)	0.714	0.286
M25.58 Pain in joint (Other)	0.713	0.286
M25.52 Pain in joint (Upper arm)	0.713	0.286
Q63 Other congenital malformations of kidney	0.712	0.288
Chapter XXI Factors influencing health status and contact with health services	0.712	0.288
M31 Other necrotising vasculopathies	0.711	0.289
M17.4 Other secondary gonarthrosis, bilateral	0.711	0.289
M17.2 Posttraumatic gonarthrosis, bilateral	0.711	0.289
M25.59 Pain in joint (Site unspecified)	0.711	0.289
L10-L14 Bullous disorders	0.711	0.289
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.710	0.289
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.710	0.290
Q50-Q56 Congenital malformations of genital organs	0.710	0.290
M48.00 Spinal stenosis (Multiple sites in spine)	0.709	0.291
D47.3 Essential (haemorrhagic) thrombocythaemia	0.708	0.292
L02.0 Cutaneous abscess, furuncle and carbuncle of face	0.707	0.293
D69.5 Secondary thrombocytopenia	0.705	0.295
Q00-Q07 Congenital malformations of the nervous system	0.705	0.295
M81 Osteoporosis without pathological fracture	0.704	0.296
M00-M03 Infectious arthropathies	0.704	0.296
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.703	0.297
S62 Fracture at wrist and hand level	0.703	0.297
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.702	0.298
M25.06 Haemarthrosis (Lower leg)	0.701	0.299
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.701	0.299
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.701	0.299
S20 Superficial injury of thorax	0.700	0.300
T39.0 Salicylates	0.700	0.300
M19.01 Primary arthrosis of other joints (Shoulder region)	0.699	0.301
S64.4 Injury of digital nerve of other finger	0.699	0.301
I25.2 Old myocardial infarction	0.699	0.301
D80-D89 Certain disorders involving the immune mechanism	0.699	0.301
I60-I69 Cerebrovascular diseases	0.698	0.302
L03.0 Cellulitis of finger and toe	0.698	0.302
G20 Parkinson's disease	0.697	0.303
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.697	0.303
S22 Fracture of rib(s), sternum and thoracic spine	0.697	0.303
M76 Enthesopathies of lower limb, excluding foot	0.696	0.303
M73 Soft tissue disorders in diseases classified elsewhere	0.696	0.303
M65.8 Other synovitis and tenosynovitis	0.696	0.304
D68.2 Hereditary deficiency of other clotting factors	0.694	0.306
G93.2 Benign intracranial hypertension	0.693	0.307
M19.03 Primary arthrosis of other joints (Forearm)	0.692	0.308
M71 Other bursopathies	0.692	0.308
S50-S59 Injuries to the elbow and forearm	0.691	0.309
S82 Fracture of lower leg, including ankle	0.691	0.309
T39.1 4-Aminophenol derivatives	0.690	0.310
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.690	0.310
M45 Ankylosing spondylitis	0.690	0.310
C66 Malignant neoplasm of ureter	0.689	0.311
M84.1 Nonunion of fracture [pseudarthrosis]	0.688	0.312
D67 Hereditary factor IX deficiency	0.686	0.314
D66 Hereditary factor VIII deficiency	0.686	0.314
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.686	0.314
M65.3 Trigger finger	0.686	0.314
S61.9 Open wound of wrist and hand, part unspecified	0.685	0.315
G93.5 Compression of brain	0.685	0.315
Q61 Cystic kidney disease	0.685	0.315
C40-C41 Malignant neoplasms of bone and articular cartilage	0.684	0.316
M25.9 Joint disorder, unspecified	0.684	0.316
Z70-Z76 Persons encountering health services in other circumstances	0.684	0.316
L92.3 Foreign body granuloma of skin and subcutaneous tissue	0.683	0.317
M75.8 Other shoulder lesions	0.682	0.317
M89.5 Osteolysis	0.682	0.318
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.682	0.318
S27 Injury of other and unspecified intrathoracic organs	0.682	0.318
S89 Other and unspecified injuries of lower leg	0.682	0.318
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.682	0.318
C50 Malignant neoplasm of breast	0.680	0.320
M19.8 Other specified arthrosis	0.680	0.320
M19.2 Other secondary arthrosis	0.680	0.320
M89.8 Other specified disorders of bone	0.680	0.320
L95 Vasculitis limited to skin, not elsewhere classified	0.679	0.321
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.679	0.321
Q35-Q37 Cleft lip and cleft palate	0.679	0.321
Q30-Q34 Congenital malformations of the respiratory system	0.679	0.321
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.679	0.321
M67.9 Disorder of synovium and tendon, unspecified	0.678	0.322
M67.4 Ganglion	0.678	0.322
M67.3 Transient synovitis	0.678	0.322
M67.1 Other contracture of tendon (sheath)	0.678	0.322
M67.0 Short Achilles tendon (acquired)	0.678	0.322
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.678	0.322
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.678	0.322
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.678	0.322
L71.1 Rhinophyma	0.678	0.322
M65.2 Calcific tendinitis	0.677	0.322
M65.0 Abscess of tendon sheath	0.677	0.322
S67 Crushing injury of wrist and hand	0.677	0.323
D69.9 Haemorrhagic condition, unspecified	0.677	0.323
D69.8 Other specified haemorrhagic conditions	0.677	0.323
D69.2 Other nonthrombocytopenic purpura	0.677	0.323
D69.1 Qualitative platelet defects	0.677	0.323
D69.0 Allergic purpura	0.677	0.323
T90 Sequelae of injuries of head	0.676	0.324
M90.7 Fracture of bone in neoplastic disease	0.674	0.326
D39.1 Ovary	0.673	0.326
M25.86 Other specified joint disorders (Lower leg)	0.673	0.327
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.673	0.327
L83 Acanthosis nigricans	0.673	0.327
L57 Skin changes due to chronic exposure to nonionising radiation	0.673	0.327
Z22 Carrier of infectious disease	0.672	0.328
T93 Sequelae of injuries of lower limb	0.672	0.328
L04 Acute lymphadenitis	0.672	0.328
L01 Impetigo	0.672	0.328
L00 Staphylococcal scalded skin syndrome	0.672	0.328
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.671	0.329
G93.0 Cerebral cysts	0.671	0.329
M25.79 Osteophyte (Site unspecified)	0.671	0.329
M25.73 Osteophyte (Forearm)	0.671	0.329
M25.72 Osteophyte (Upper arm)	0.671	0.329
M25.70 Osteophyte (Multiple sites)	0.671	0.329
L40-L45 Papulosquamous disorders	0.671	0.329
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.670	0.330
D68.9 Coagulation defect, unspecified	0.670	0.330
D68.8 Other specified coagulation defects	0.670	0.330
M23.8 Other internal derangements of knee	0.669	0.331
L84 Corns and callosities	0.669	0.331
T15-T19 Effects of foreign body entering through natural orifice	0.668	0.331
L50-L54 Urticaria and erythema	0.667	0.332
S41 Open wound of shoulder and upper arm	0.667	0.333
M89.98 Disorder of bone, unspecified (Other)	0.666	0.333
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.666	0.334
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.666	0.334
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.666	0.334
T41 Poisoning by anaesthetics and therapeutic gases	0.666	0.334
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.666	0.334
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.666	0.334
T36 Poisoning by systemic antibiotics	0.666	0.334
D55-D59 Haemolytic anaemias	0.666	0.334
S42 Fracture of shoulder and upper arm	0.666	0.334
M47.92 Spondylosis, unspecified (Cervical region)	0.665	0.335
C91 Lymphoid leukaemia	0.664	0.336
S48 Traumatic amputation of shoulder and upper arm	0.663	0.337
S45 Injury of blood vessels at shoulder and upper arm level	0.663	0.337
S44 Injury of nerves at shoulder and upper arm level	0.663	0.337
S47 Crushing injury of shoulder and upper arm	0.663	0.337
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.663	0.337
M86 Osteomyelitis	0.662	0.338
M48.5 Collapsed vertebra, not elsewhere classified	0.661	0.339
I95-I99 Other and unspecified disorders of the circulatory system	0.661	0.339
L89 Decubitus ulcer	0.660	0.340
M35 Other systemic involvement of connective tissue	0.660	0.340
Chapter VII Diseases of the eye and adnexa	0.659	0.341
L20-L30 Dermatitis and eczema	0.657	0.343
W29 Contact with other powered hand tools and household machinery	0.657	0.343
I60 Subarachnoid haemorrhage	0.657	0.343
Z75 Problems related to medical facilities and other health care	0.657	0.343
S46 Injury of muscle and tendon at shoulder and upper arm level	0.655	0.345
M47.8 Other spondylosis	0.655	0.345
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.655	0.345
M48.09 Spinal stenosis (Site unspecified)	0.655	0.345
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.654	0.346
L94 Other localised connective tissue disorders	0.654	0.346
L93 Lupus erythematosus	0.654	0.346
L87 Transepidermal elimination disorders	0.654	0.346
L88 Pyoderma gangrenosum	0.654	0.346
L86 Keratoderma in diseases classified elsewhere	0.654	0.346
L80 Vitiligo	0.654	0.346
G90 Disorders of autonomic nervous system	0.654	0.346
L92.0 Granuloma annulare	0.654	0.346
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.652	0.347
X60-X84 Intentional self-harm	0.652	0.348
M70.65 Trochanteric bursitis-Pelvic/Thigh	0.652	0.348
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.651	0.349
M25.54 Pain in joint (Hand)	0.651	0.349
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.650	0.350
M47.1 Other spondylosis with myelopathy	0.648	0.352
M34 Systemic sclerosis	0.648	0.352
C97 Malignant neoplasms of independent (primary) multiple sites	0.648	0.352
S69 Other and unspecified injuries of wrist and hand	0.647	0.353
S86 Injury of muscle and tendon at lower leg level	0.646	0.354
M48.07 Spinal stenosis (Lumbosacral region)	0.646	0.354
M21.0 Valgus deformity, not elsewhere classified	0.646	0.354
G91 Hydrocephalus	0.644	0.356
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.644	0.356
M22 Disorders of patella	0.644	0.356
M25.53 Pain in joint (Forearm)	0.643	0.356
G35-G37 Demyelinating diseases of the central nervous system	0.643	0.357
M25.51 Pain in joint (Shoulder region)	0.642	0.358
Z29 Need for other prophylactic measures	0.642	0.358
W22 Striking against or struck by other objects	0.642	0.358
L03.8 Cellulitis of other sites	0.640	0.360
T95 Sequelae of burns, corrosions and frostbite	0.640	0.360
T94 Sequelae of injuries involving multiple and unspecified body regions	0.640	0.360
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.640	0.360
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.640	0.360
M17.3 Other posttraumatic gonarthrosis	0.639	0.360
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.639	0.361
L92.8 Other granulomatous disorders of skin and subcutaneous tissue	0.639	0.361
M25.78 Osteophyte (Other)	0.638	0.362
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.638	0.362
W49 Exposure to other and unspecified inanimate mechanical forces	0.638	0.362
S30 Superficial injury of abdomen, lower back and pelvis	0.638	0.362
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)	0.638	0.362
M65.98 Synovitis and tenosynovitis, unspecified (Other)	0.638	0.362
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.638	0.362
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.638	0.362
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle	0.637	0.363
S43.6 Sprain and strain of sternoclavicular joint	0.637	0.363
S43.5 Sprain and strain of acromioclavicular joint	0.637	0.363
S43.4 Sprain and strain of shoulder joint	0.637	0.363
S43.3 Dislocation of other and unspecified parts of shoulder girdle	0.637	0.363
S43.2 Dislocation of sternoclavicular joint	0.637	0.363
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.637	0.363
T68 Hypothermia	0.637	0.363
T98 Sequelae of other and unspecified effects of external causes	0.637	0.363
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.636	0.363
C95 Leukaemia of unspecified cell type	0.636	0.363
C94 Other leukaemias of specified cell type	0.636	0.363
C93 Monocytic leukaemia	0.636	0.363
C88 Malignant immunoproliferative diseases	0.636	0.363
C86 Other specified types of T/NK-cell lymphoma	0.636	0.363
M25.89 Other specified joint disorders (Site unspecified)	0.635	0.365
M25.88 Other specified joint disorders (Other)	0.635	0.365
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.635	0.365
M25.83 Other specified joint disorders (Forearm)	0.635	0.365
M25.82 Other specified joint disorders (Upper arm)	0.635	0.365
M25.81 Other specified joint disorders (Shoulder region)	0.635	0.365
M25.80 Other specified joint disorders (Multiple sites)	0.635	0.365
S61.8 Open wound of other parts of wrist and hand	0.634	0.366
S31 Open wound of abdomen, lower back and pelvis	0.634	0.366
S10 Superficial injury of neck	0.634	0.366
L75 Apocrine sweat disorders	0.634	0.366
L74 Eccrine sweat disorders	0.634	0.366
L70 Acne	0.634	0.366
L68 Hypertrichosis	0.634	0.366
L67 Hair colour and hair shaft abnormalities	0.634	0.366
L66 Cicatricial alopecia [scarring hair loss]	0.634	0.366
L65 Other nonscarring hair loss	0.634	0.366
L64 Androgenic alopecia	0.634	0.366
L63 Alopecia areata	0.634	0.366
L62 Nail disorders in diseases classified elsewhere	0.634	0.366
D68.4 Acquired coagulation factor deficiency	0.634	0.366
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.634	0.366
D68.1 Hereditary factor XI deficiency	0.634	0.366
V40-V49 Car occupant injured in transport accident	0.633	0.367
S32 Fracture of lumbar spine and pelvis	0.633	0.367
M19.02 Primary arthrosis of other joints (Upper arm)	0.633	0.367
G72 Other myopathies	0.633	0.367
C67 Malignant neoplasm of bladder	0.633	0.367
M82 Osteoporosis in diseases classified elsewhere	0.633	0.367
M89.6 Osteopathy after poliomyelitis	0.632	0.368
M89.4 Other hypertrophic osteo-arthropathy	0.632	0.368
M89.3 Hypertrophy of bone	0.632	0.368
M89.2 Other disorders of bone development and growth	0.632	0.368
M89.1 Epiphyseal arrest	0.632	0.368
M89.0 Algoneurodystrophy	0.632	0.368
M83 Adult osteomalacia	0.632	0.368
M19.1 Posttraumatic arthrosis of other joints	0.631	0.368
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.631	0.369
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.630	0.369
M48.9 Spondylopathy, unspecified	0.630	0.370
M48.8 Other specified spondylopathies	0.630	0.370
M48.4 Fatigue fracture of vertebra	0.630	0.370
M48.3 Traumatic spondylopathy	0.630	0.370
M48.2 Kissing spine	0.630	0.370
M48.1 Ankylosing hyperostosis [Forestier]	0.630	0.370
S88 Traumatic amputation of lower leg	0.630	0.370
S87 Crushing injury of lower leg	0.630	0.370
S85 Injury of blood vessels at lower leg level	0.630	0.370
S84 Injury of nerves at lower leg level	0.630	0.370
S49 Other and unspecified injuries of shoulder and upper arm	0.630	0.370
S29 Other and unspecified injuries of thorax	0.629	0.371
M46.9 Inflammatory spondylopathy, unspecified	0.629	0.371
L81.9 Disorder of pigmentation, unspecified	0.629	0.371
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.628	0.371
D37.9 Digestive organ, unspecified	0.628	0.372
D37.3 Appendix	0.628	0.372
D37.2 Small intestine	0.628	0.372
D37.0 Lip, oral cavity and pharynx	0.628	0.372
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.628	0.372
S60.8 Other superficial injuries of wrist and hand	0.626	0.374
X20-X29 Contact with venomous animals and plants	0.626	0.374
G93.1 Anoxic brain damage, not elsewhere classified	0.626	0.374
S12 Fracture of neck	0.626	0.374
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.625	0.375
S26 Injury of heart	0.625	0.375
S25 Injury of blood vessels of thorax	0.625	0.375
S24 Injury of nerves and spinal cord at thorax level	0.625	0.375
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.625	0.375
S21 Open wound of thorax	0.625	0.375
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.625	0.375
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.625	0.375
T39.4 Antirheumatics, not elsewhere classified	0.625	0.375
T39.2 Pyrazolone derivatives	0.625	0.375
C81.1 Nodular sclerosis	0.624	0.376
M25.71 Osteophyte (Shoulder region)	0.623	0.376
M85 Other disorders of bone density and structure	0.623	0.377
M47.99 Spondylosis, unspecified (Site unspecified)	0.623	0.377
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.622	0.378
C90.2 Plasmacytoma, extramedullary	0.622	0.378
M19.95 Arthrosis, unspecified (Pelvic region and thigh)	0.621	0.378
Z22.3 Carrier of other specified bacterial diseases	0.621	0.379
M19.92 Arthrosis, unspecified (Upper arm)	0.621	0.379
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.621	0.379
S61.7 Multiple open wounds of wrist and hand	0.620	0.379
D37.1 Stomach	0.620	0.380
S99 Other and unspecified injuries of ankle and foot	0.620	0.380
C84.4 Peripheral T-cell lymphoma	0.620	0.380
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites	0.619	0.381
M19.04 Primary arthrosis of other joints (Hand)	0.618	0.382
W50-W64 Exposure to animate mechanical forces	0.618	0.382
M47.0 Anterior spinal and vertebral artery compression syndromes	0.618	0.382
G71 Primary disorders of muscles	0.618	0.382
S92 Fracture of foot, except ankle	0.617	0.383
Chapter XXII Codes for special purposes	0.617	0.383
M19.98 Arthrosis, unspecified (Other)	0.616	0.383

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations