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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs116570129
log Bayes Factor = 18.625
Chromosome 1   position 171,808,179  (GRCh37) Explore rs116570129 on Ensembl!
Variant rs116570129 is part of Cluster X0045

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
R10-R19 Symptoms and signs involving the digestive system and abdomen
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
1.000 0.000 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
1.000 0.000 0.000
R10 Abdominal and pelvic pain
0.999 0.001 0.000
K20 Oesophagitis
0.999 0.001 0.000
R19.4 Change in bowel habit
0.998 0.002 0.000
R10.1 Pain localised to upper abdomen
0.990 0.010 0.000
Chapter VI Diseases of the nervous system
0.989 0.011 0.000
Chapter I Certain infectious and parasitic diseases
0.988 0.012 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.987 0.013 0.000
Chapter XIV Diseases of the genitourinary system
0.984 0.016 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.981 0.019 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.971 0.029 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.969 0.031 0.000
R19.5 Other fecal abnormalities
0.969 0.031 0.000
Chapter XXI Factors influencing health status and contact with health services
0.965 0.035 0.000
R10.4 Other and unspecified abdominal pain
0.964 0.036 0.000
B35-B49 Mycoses
0.964 0.036 0.000
K40-K46 Hernia
0.964 0.036 0.000
R13 Dysphagia
0.963 0.037 0.000
N17-N19 Renal failure
0.961 0.039 0.000
K44 Diaphragmatic hernia
0.949 0.051 0.000
K22 Other diseases of oesophagus
0.945 0.055 0.000
M20-M25 Other joint disorders
0.942 0.058 0.000
B37 Candidiasis
0.940 0.060 0.000
K44.9 Diaphragmatic hernia without obstruction or gangrene
0.939 0.061 0.000
Chapter XX External causes of morbidity and mortality
0.936 0.064 0.000
K50-K52 Noninfective enteritis and colitis
0.934 0.066 0.000
Chapter V Mental and behavioural disorders
0.934 0.066 0.000
E70-E90 Metabolic disorders
0.933 0.067 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.933 0.067 0.000
A00-A09 Intestinal infectious diseases
0.929 0.071 0.000
N10-N16 Renal tubulo-interstitial diseases
0.928 0.072 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.921 0.079 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.920 0.080 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.920 0.080 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.918 0.082 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.914 0.086 0.000
K65-K67 Diseases of peritoneum
0.911 0.089 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.908 0.092 0.000
N18 Chronic renal failure
0.908 0.092 0.000
M23 Internal derangement of knee
0.906 0.094 0.000
K31 Other diseases of stomach and duodenum
0.900 0.100 0.000
K22.8 Other specified diseases of oesophagus
0.899 0.101 0.000
N13 Obstructive and reflux uropathy
0.897 0.103 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.888 0.112 0.000
Z03.4 Observation for suspected myocardial infarction
0.886 0.114 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.883 0.117 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.882 0.118 0.000
B37.8 Candidiasis of other sites
0.881 0.118 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.881 0.119 0.000
K26 Duodenal ulcer
0.880 0.120 0.000
K29 Gastritis and duodenitis
0.879 0.121 0.000
G20-G26 Extrapyramidal and movement disorders
0.878 0.122 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.873 0.127 0.000
K52 Other non-infective gastro-enteritis and colitis
0.867 0.133 0.000
R06 Abnormalities of breathing
0.862 0.138 0.000
G30-G32 Other degenerative diseases of the nervous system
0.858 0.142 0.000
R10.3 Pain localised to other parts of lower abdomen
0.858 0.142 0.000
A08 Viral and other specified intestinal infections
0.857 0.143 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.857 0.143 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.857 0.143 0.000
E83 Disorders of mineral metabolism
0.857 0.143 0.000
M70-M79 Other soft tissue disorders
0.856 0.144 0.000
Chapter VIII Diseases of the ear and mastoid process
0.854 0.146 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.854 0.146 0.000
L60-L75 Disorders of skin appendages
0.852 0.148 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.851 0.149 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.850 0.150 0.000
N40-N51 Diseases of male genital organs
0.849 0.151 0.000
G40-G47 Episodic and paroxysmal disorders
0.849 0.151 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.844 0.156 0.000
K66 Other disorders of peritoneum
0.840 0.160 0.000
N17 Acute renal failure
0.836 0.164 0.000
M05-M14 Inflammatory polyarthropathies
0.834 0.166 0.000
B37.9 Candidiasis, unspecified
0.830 0.170 0.000
O60-O75 Complications of labour and delivery
0.830 0.170 0.000
S80-S89 Injuries to the knee and lower leg
0.825 0.175 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.825 0.175 0.000
E20-E35 Disorders of other endocrine glands
0.823 0.177 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.822 0.178 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.821 0.179 0.000
N13.3 Other and unspecified hydronephrosis
0.821 0.179 0.000
K43 Ventral hernia
0.818 0.182 0.000
N18.9 Chronic renal failure, unspecified
0.815 0.185 0.000
K51 Ulcerative colitis
0.815 0.185 0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.812 0.188 0.000
R06.0 Dyspnoea
0.810 0.190 0.000
O36 Maternal care for other known or suspected foetal problems
0.807 0.193 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.806 0.194 0.000
M25 Other joint disorders, not elsewhere classified
0.806 0.194 0.000
G90-G99 Other disorders of the nervous system
0.806 0.194 0.000
A08.4 Viral intestinal infection, unspecified
0.806 0.194 0.000
Chapter X Diseases of the respiratory system
0.803 0.197 0.000
G62 Other polyneuropathies
0.801 0.199 0.000
M65-M68 Disorders of synovium and tendon
0.801 0.199 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.798 0.202 0.000
E10-E14 Diabetes mellitus
0.798 0.202 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.796 0.204 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.794 0.206 0.000
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.794 0.206 0.000
R10.0 Acute abdomen
0.794 0.206 0.000
O47 False labour
0.794 0.206 0.000
Z48 Other surgical follow-up care
0.792 0.208 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.792 0.208 0.000
N18.0 End-stage renal disease
0.792 0.208 0.000
K66.0 Peritoneal adhesions
0.790 0.210 0.000
Y95 Nosocomial condition
0.790 0.210 0.000
K31.8 Other specified diseases of stomach and duodenum
0.788 0.212 0.000
R47-R49 Symptoms and signs involving speech and voice
0.787 0.213 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.787 0.213 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.787 0.213 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.784 0.216 0.000
L72.1 Trichilemmal cyst
0.780 0.220 0.000
K22.2 Oesophageal obstruction
0.780 0.220 0.000
N19 Unspecified renal failure
0.779 0.221 0.000
N25-N29 Other disorders of kidney and ureter
0.779 0.221 0.000
K29.6 Other gastritis
0.779 0.221 0.000
Z02 Examination and encounter for administrative purposes
0.778 0.222 0.000
W20-W49 Exposure to inanimate mechanical forces
0.778 0.222 0.000
E86 Volume depletion
0.778 0.222 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.776 0.223 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.776 0.224 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.774 0.226 0.000
N72 Inflammatory disease of cervix uteri
0.773 0.227 0.000
N00-N08 Glomerular diseases
0.773 0.227 0.000
B44 Aspergillosis
0.772 0.228 0.000
R06.4 Hyperventilation
0.771 0.229 0.000
K22.7 Barrett's oesophagus
0.770 0.230 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.767 0.233 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.766 0.234 0.000
S20-S29 Injuries to the thorax
0.766 0.234 0.000
N13.4 Hydroureter
0.765 0.235 0.000
R02 Gangrene, not elsewhere classified
0.765 0.235 0.000
G24 Dystonia
0.763 0.237 0.000
T66-T78 Other and unspecified effects of external causes
0.761 0.238 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.761 0.239 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.760 0.240 0.000
K29.7 Gastritis, unspecified
0.760 0.240 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.760 0.240 0.000
N99-N99 Other disorders of the genitourinary system
0.758 0.241 0.000
E83.1 Disorders of iron metabolism
0.758 0.242 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.758 0.242 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.757 0.243 0.000
F03 Unspecified dementia
0.756 0.244 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.755 0.245 0.000
M22 Disorders of patella
0.754 0.246 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.754 0.246 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.753 0.247 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.752 0.247 0.000
Z03.9 Observation for suspected disease or condition, unspecified
0.751 0.249 0.000
K70-K77 Diseases of liver
0.750 0.250 0.000
K29.0 Acute haemorrhagic gastritis
0.750 0.250 0.000
Chapter XXII Codes for special purposes
0.750 0.250 0.000
N48 Other disorders of penis
0.748 0.252 0.000
N17.9 Acute renal failure, unspecified
0.747 0.253 0.000
T86 Failure and rejection of transplanted organs and tissues
0.745 0.255 0.000
R20 Disturbances of skin sensation
0.745 0.255 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.745 0.255 0.000
R18 Ascites
0.744 0.256 0.000
Z48.0 Attention to surgical dressings and sutures
0.743 0.257 0.000
M23.8 Other internal derangements of knee
0.743 0.257 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.742 0.258 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.742 0.258 0.000
M80-M85 Disorders of bone density and structure
0.740 0.260 0.000
E87.2 Acidosis
0.740 0.260 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.740 0.260 0.000
Chapter IX Diseases of the circulatory system
0.740 0.260 0.000
G70-G73 Diseases of myoneural junction and muscle
0.739 0.261 0.000
Z48.8 Other specified surgical follow-up care
0.739 0.261 0.000
N41 Inflammatory diseases of prostate
0.737 0.263 0.000
K90-K93 Other diseases of the digestive system
0.737 0.263 0.000
M10 Gout
0.736 0.264 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.735 0.265 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.733 0.267 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.733 0.267 0.000
K31.9 Disease of stomach and duodenum, unspecified
0.733 0.267 0.000
O36.8 Maternal care for other specified foetal problems
0.733 0.267 0.000
L20-L30 Dermatitis and eczema
0.733 0.267 0.000
K51.9 Ulcerative colitis, unspecified
0.732 0.268 0.000
E50-E64 Other nutritional deficiencies
0.732 0.268 0.000
O41 Other disorders of amniotic fluid and membranes
0.731 0.269 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.729 0.271 0.000
L08 Other local infections of skin and subcutaneous tissue
0.728 0.272 0.000
R21 Rash and other nonspecific skin eruption
0.728 0.272 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.727 0.272 0.000
R01 Cardiac murmurs and other cardiac sounds
0.727 0.273 0.000
G25 Other extrapyramidal and movement disorders
0.727 0.273 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.725 0.275 0.000
G30 Alzheimer's disease
0.725 0.275 0.000
G60 Hereditary and idiopathic neuropathy
0.724 0.276 0.000
H90-H95 Other disorders of ear
0.723 0.276 0.000
N18.2 Chronic kidney disease, stage 2
0.722 0.277 0.000
O20 Haemorrhage in early pregnancy
0.719 0.280 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.719 0.281 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.719 0.281 0.000
J95-J99 Other diseases of the respiratory system
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
K28 Gastrojejunal ulcer
0.717 0.283 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.717 0.283 0.000
H60-H62 Diseases of external ear
0.717 0.283 0.000
R19.6 Halitosis
0.717 0.283 0.000
R19.3 Abdominal rigidity
0.717 0.283 0.000
R19.2 Visible peristalsis
0.717 0.283 0.000
R19.1 Abnormal bowel sounds
0.717 0.283 0.000
A30-A49 Other bacterial diseases
0.716 0.284 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.715 0.285 0.000
E10 Insulin-dependent diabetes mellitus
0.714 0.286 0.000
R15 Faecal incontinence
0.714 0.286 0.000
F00 Dementia in Alzheimer's disease
0.713 0.286 0.000
B37.0 Candidal stomatitis
0.713 0.287 0.000
S40-S49 Injuries to the shoulder and upper arm
0.713 0.287 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.713 0.287 0.000
B37.3 Candidiasis of vulva and vagina
0.712 0.288 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.711 0.289 0.000
N76 Other inflammation of vagina and vulva
0.711 0.289 0.000
L50-L54 Urticaria and erythema
0.710 0.290 0.000
Z22 Carrier of infectious disease
0.710 0.290 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.709 0.291 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.709 0.291 0.000
E87.6 Hypokalaemia
0.709 0.291 0.000
Z35 Supervision of high-risk pregnancy
0.709 0.291 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.709 0.291 0.000
B99-B99 Other infectious diseases
0.708 0.292 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.708 0.292 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.708 0.292 0.000
B65-B83 Helminthiases
0.708 0.292 0.000
B50-B64 Protozoal diseases
0.708 0.292 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.708 0.292 0.000
B15-B19 Viral hepatitis
0.708 0.292 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.708 0.292 0.000
A80-A89 Viral infections of the central nervous system
0.708 0.292 0.000
A75-A79 Rickettsioses
0.708 0.292 0.000
A70-A74 Other diseases caused by chlamydiae
0.708 0.292 0.000
A65-A69 Other spirochaetal diseases
0.708 0.292 0.000
A20-A28 Certain zoonotic bacterial diseases
0.708 0.292 0.000
A15-A19 Tuberculosis
0.708 0.292 0.000
M24 Other specific joint derangements
0.708 0.292 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.708 0.292 0.000
T79-T79 Certain early complications of trauma
0.708 0.292 0.000
T33-T35 Frostbite
0.708 0.292 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.708 0.292 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.708 0.292 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.708 0.292 0.000
T00-T07 Injuries involving multiple body regions
0.708 0.292 0.000
S90-S99 Injuries to the ankle and foot
0.708 0.292 0.000
S10-S19 Injuries to the neck
0.708 0.292 0.000
Z42 Follow-up care involving plastic surgery
0.707 0.293 0.000
M79.8 Other specified soft tissue disorders
0.706 0.294 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.706 0.294 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.706 0.294 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.706 0.294 0.000
M45-M49 Spondylopathies
0.705 0.295 0.000
R12 Heartburn
0.704 0.296 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.703 0.297 0.000
M91-M94 Chondropathies
0.703 0.297 0.000
M60-M63 Disorders of muscles
0.703 0.297 0.000
M00-M03 Infectious arthropathies
0.703 0.297 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.703 0.297 0.000
G40 Epilepsy
0.702 0.297 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.702 0.298 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.702 0.298 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.702 0.298 0.000
Z03.3 Observation for suspected nervous system disorder
0.699 0.301 0.000
R79 Other abnormal findings of blood chemistry
0.698 0.301 0.000
K27 Peptic ulcer, site unspecified
0.698 0.302 0.000
R07 Pain in throat and chest
0.698 0.302 0.000
S70-S79 Injuries to the hip and thigh
0.698 0.302 0.000
M40-M43 Deforming dorsopathies
0.696 0.304 0.000
O85-O92 Complications predominantly related to the puerperium
0.696 0.304 0.000
S32 Fracture of lumbar spine and pelvis
0.696 0.304 0.000
O26.8 Other specified pregnancy-related conditions
0.695 0.305 0.000
E40-E46 Malnutrition
0.695 0.305 0.000
G62.9 Polyneuropathy, unspecified
0.695 0.305 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.694 0.305 0.000
M21 Other acquired deformities of limbs
0.694 0.306 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.692 0.308 0.000
N18.5 Chronic kidney disease, stage 5
0.692 0.308 0.000
B48 Other mycoses, not elsewhere classified
0.691 0.309 0.000
B47 Mycetoma
0.691 0.309 0.000
B46 Zygomycosis
0.691 0.309 0.000
B45 Cryptococcosis
0.691 0.309 0.000
B43 Chromomycosis and phaeomycotic abscess
0.691 0.309 0.000
B42 Sporotrichosis
0.691 0.309 0.000
B41 Paracoccidioidomycosis
0.691 0.309 0.000
B40 Blastomycosis
0.691 0.309 0.000
B39 Histoplasmosis
0.691 0.309 0.000
B38 Coccidioidomycosis
0.691 0.309 0.000
B36 Other superficial mycoses
0.691 0.309 0.000
B35 Dermatophytosis
0.691 0.309 0.000
B49 Unspecified mycosis
0.691 0.309 0.000
G44 Other headache syndromes
0.691 0.309 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.691 0.309 0.000
K45 Other abdominal hernia
0.691 0.309 0.000
O48 Prolonged pregnancy
0.690 0.310 0.000
O66 Other obstructed labour
0.689 0.311 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.688 0.312 0.000
O24 Diabetes mellitus in pregnancy
0.688 0.312 0.000
W00-W19 Falls
0.687 0.313 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.686 0.313 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.686 0.314 0.000
K43.9 Ventral hernia without obstruction or gangrene
0.686 0.314 0.000
R45 Symptoms and signs involving emotional state
0.686 0.314 0.000
K46 Unspecified abdominal hernia
0.686 0.314 0.000
Z01.4 Gynaecological examination (general)(routine)
0.684 0.316 0.000
Z49 Care involving dialysis
0.684 0.316 0.000
E88 Other metabolic disorders
0.683 0.317 0.000
O42 Premature rupture of membranes
0.682 0.318 0.000
E83.4 Disorders of magnesium metabolism
0.682 0.318 0.000
N13.8 Other obstructive and reflux uropathy
0.682 0.318 0.000
G61 Inflammatory polyneuropathy
0.682 0.318 0.000
K44.1 Diaphragmatic hernia with gangrene
0.681 0.319 0.000
K44.0 Diaphragmatic hernia with obstruction, without gangrene
0.681 0.319 0.000
S82 Fracture of lower leg, including ankle
0.679 0.321 0.000
K65 Peritonitis
0.679 0.321 0.000
Z02.8 Other examinations for administrative purposes
0.679 0.321 0.000
K22.5 Diverticulum of oesophagus, acquired
0.677 0.323 0.000
K22.3 Perforation of oesophagus
0.677 0.323 0.000
K22.0 Achalasia of cardia
0.677 0.323 0.000
S00-S09 Injuries to the head
0.677 0.323 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.677 0.323 0.000
R14 Flatulence and related conditions
0.677 0.323 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.676 0.324 0.000
M86-M90 Other osteopathies
0.676 0.324 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.675 0.324 0.000
M34 Systemic sclerosis
0.675 0.324 0.000
M33 Dermatopolymyositis
0.675 0.324 0.000
M32 Systemic lupus erythematosus
0.675 0.324 0.000
M30 Polyarteritis nodosa and related conditions
0.675 0.324 0.000
M25.0 Haemarthrosis
0.675 0.325 0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis
0.675 0.325 0.000
M23.4 Loose body in knee
0.674 0.326 0.000
B37.7 Candidal septicaemia
0.674 0.326 0.000
B37.6 Candidal endocarditis
0.674 0.326 0.000
B37.5 Candidal meningitis
0.674 0.326 0.000
B37.4 Candidiasis of other urogenital sites
0.674 0.326 0.000
B37.2 Candidiasis of skin and nail
0.674 0.326 0.000
B37.1 Pulmonary candidiasis
0.674 0.326 0.000
S60-S69 Injuries to the wrist and hand
0.672 0.328 0.000
X60-X84 Intentional self-harm
0.671 0.329 0.000
E83.3 Disorders of phosphorus metabolism
0.671 0.329 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.671 0.329 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.671 0.329 0.000
Y35-Y36 Legal intervention and operations of war
0.671 0.329 0.000
Y10-Y34 Event of undetermined intent
0.671 0.329 0.000
Y00-Y09 Assault
0.671 0.329 0.000
X85-X99 Assault
0.671 0.329 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.671 0.329 0.000
X50-X57 Overexertion, travel and privation
0.671 0.329 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.671 0.329 0.000
X30-X39 Exposure to forces of nature
0.671 0.329 0.000
X20-X29 Contact with venomous animals and plants
0.671 0.329 0.000
X10-X19 Contact with heat and hot substances
0.671 0.329 0.000
X00-X09 Exposure to smoke, fire and flames
0.671 0.329 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.671 0.329 0.000
W75-W84 Other accidental threats to breathing
0.671 0.329 0.000
W65-W74 Accidental drowning and submersion
0.671 0.329 0.000
W50-W64 Exposure to animate mechanical forces
0.671 0.329 0.000
V98-V99 Other and unspecified transport accidents
0.671 0.329 0.000
V95-V97 Air and space transport accidents
0.671 0.329 0.000
V90-V94 Water transport accidents
0.671 0.329 0.000
V80-V89 Other land transport accidents
0.671 0.329 0.000
V70-V79 Bus occupant injured in transport accident
0.671 0.329 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.671 0.329 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.671 0.329 0.000
V40-V49 Car occupant injured in transport accident
0.671 0.329 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.671 0.329 0.000
V20-V29 Motorcycle rider injured in transport accident
0.671 0.329 0.000
V01-V09 Pedestrian injured in transport accident
0.671 0.329 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.670 0.330 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.670 0.330 0.000
F99-F99 Unspecified mental disorder
0.669 0.330 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.669 0.330 0.000
F80-F89 Disorders of psychological development
0.669 0.330 0.000
F70-F79 Mental retardation
0.669 0.330 0.000
F60-F69 Disorders of adult personality and behaviour
0.669 0.330 0.000
E85 Amyloidosis
0.669 0.331 0.000
E84 Cystic fibrosis
0.669 0.331 0.000
E79 Disorders of purine and pyrimidine metabolism
0.669 0.331 0.000
E77 Disorders of glycoprotein metabolism
0.669 0.331 0.000
E76 Disorders of glycosaminoglycan metabolism
0.669 0.331 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.669 0.331 0.000
E74 Other disorders of carbohydrate metabolism
0.669 0.331 0.000
E73 Lactose intolerance
0.669 0.331 0.000
E72 Other disorders of amino-acid metabolism
0.669 0.331 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.669 0.331 0.000
E70 Disorders of aromatic amino-acid metabolism
0.669 0.331 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.669 0.331 0.000
L10-L14 Bullous disorders
0.669 0.331 0.000
R10.2 Pelvic and perineal pain
0.669 0.331 0.000
A07 Other protozoal intestinal diseases
0.666 0.334 0.000
A06 Amoebiasis
0.666 0.334 0.000
A05 Other bacterial foodborne intoxications
0.666 0.334 0.000
A03 Shigellosis
0.666 0.334 0.000
A02 Other Salmonella infections
0.666 0.334 0.000
A01 Typhoid and paratyphoid fevers
0.666 0.334 0.000
A00 Cholera
0.666 0.334 0.000
F30-F39 Mood [affective] disorders
0.666 0.334 0.000
I78 Diseases of capillaries
0.666 0.334 0.000
R73 Elevated blood glucose level
0.666 0.334 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.665 0.334 0.000
N15 Other renal tubulo-interstitial diseases
0.665 0.334 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.665 0.334 0.000
N11 Chronic tubulo-interstitial nephritis
0.665 0.334 0.000
N10 Acute tubulo-interstitial nephritis
0.665 0.334 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.666 0.334 0.000
M10.9 Gout, unspecified
0.666 0.334 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.665 0.335 0.000
E87.0 Hyperosmolality and hypernatraemia
0.664 0.335 0.000
V10-V19 Pedal cyclist injured in transport accident
0.664 0.336 0.000
Z03.8 Observation for other suspected diseases and conditions
0.663 0.337 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.662 0.338 0.000
K29.5 Chronic gastritis, unspecified
0.662 0.338 0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.662 0.338 0.000
M31 Other necrotising vasculopathies
0.661 0.339 0.000
K29.4 Chronic atrophic gastritis
0.661 0.339 0.000
Z03.1 Observation for suspected malignant neoplasm
0.661 0.339 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.661 0.339 0.000
O45 Premature separation of placenta [abruptio placentae]
0.660 0.340 0.000
O44 Placenta praevia
0.660 0.340 0.000
O43 Placental disorders
0.660 0.340 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.660 0.340 0.000
O33 Maternal care for known or suspected disproportion
0.660 0.340 0.000
O31 Complications specific to multiple gestation
0.660 0.340 0.000
O30 Multiple gestation
0.660 0.340 0.000
O40 Polyhydramnios
0.660 0.340 0.000
S50-S59 Injuries to the elbow and forearm
0.660 0.340 0.000
R19.8 Other specified symptoms and signs involving the digestive system and abdomen
0.660 0.340 0.000
T87 Complications peculiar to reattachment and amputation
0.659 0.340 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.659 0.340 0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.658 0.342 0.000
Z10 Routine general health check-up of defined subpopulation
0.658 0.342 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.658 0.342 0.000
M65 Synovitis and tenosynovitis
0.655 0.344 0.000
G64 Other disorders of peripheral nervous system
0.655 0.345 0.000
N48.4 Impotence of organic origin
0.655 0.345 0.000
K22.4 Dyskinesia of oesophagus
0.654 0.346 0.000
K52.8 Other specified non-infective gastro-enteritis and colitis
0.654 0.346 0.000
K67 Disorders of peritoneum in infectious diseases classified elsewhere
0.653 0.347 0.000
N70 Salpingitis and oophoritis
0.653 0.347 0.000
M25.7 Osteophyte
0.652 0.348 0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.651 0.349 0.000
Z03.6 Observation for suspected toxic effect from ingested substance
0.651 0.349 0.000
Z03.2 Observation for suspected mental and behavioural disorders
0.651 0.349 0.000
Z03.0 Observation for suspected tuberculosis
0.651 0.349 0.000
N18.8 Other chronic renal failure
0.651 0.349 0.000
N18.4 Chronic kidney disease, stage 4
0.651 0.349 0.000
N18.1 Chronic kidney disease, stage 1
0.651 0.349 0.000
J60-J70 Lung diseases due to external agents
0.651 0.349 0.000
R40 Somnolence, stupor and coma
0.650 0.350 0.000
M23.9 Internal derangement of knee, unspecified
0.650 0.350 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.650 0.350 0.000
M23.5 Chronic instability of knee
0.650 0.350 0.000
M23.1 Discoid meniscus (congenital)
0.650 0.350 0.000
M23.0 Cystic meniscus
0.650 0.350 0.000
E87.5 Hyperkalaemia
0.650 0.350 0.000
K31.7 Polyp of stomach and duodenum
0.649 0.351 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.649 0.351 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.646 0.354 0.000
N45 Orchitis and epididymitis
0.646 0.354 0.000
K31.6 Fistula of stomach and duodenum
0.645 0.355 0.000
K31.5 Obstruction of duodenum
0.645 0.355 0.000
K31.4 Gastric diverticulum
0.645 0.355 0.000
K31.3 Pylorospasm, not elsewhere classified
0.645 0.355 0.000
K31.2 Hourglass stricture and stenosis of stomach
0.645 0.355 0.000
K31.1 Adult hypertrophic pyloric stenosis
0.645 0.355 0.000
K31.0 Acute dilatation of stomach
0.645 0.355 0.000
H80-H83 Diseases of inner ear
0.645 0.355 0.000
O20.9 Haemorrhage in early pregnancy, unspecified
0.645 0.355 0.000
E23 Hypofunction and other disorders of pituitary gland
0.644 0.356 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.643 0.357 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.643 0.357 0.000
N13.6 Pyonephrosis
0.643 0.357 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.643 0.357 0.000
O47.0 False labour before 37 completed weeks of gestation
0.643 0.357 0.000
R04 Haemorrhage from respiratory passages
0.643 0.357 0.000
K41 Femoral hernia
0.641 0.359 0.000
M50-M54 Other dorsopathies
0.641 0.359 0.000
T82.1 Mechanical complication of cardiac electronic device
0.640 0.360 0.000
R76 Other abnormal immunological findings in serum
0.639 0.361 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.638 0.361 0.000
K22.9 Disease of oesophagus, unspecified
0.637 0.363 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.637 0.363 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.637 0.363 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.637 0.363 0.000
J09-J18 Influenza and pneumonia
0.637 0.363 0.000
W21 Striking against or struck by sports equipment
0.637 0.363 0.000
O29 Complications of anaesthesia during pregnancy
0.636 0.363 0.000
O28 Abnormal findings on antenatal screening of mother
0.636 0.363 0.000
O23 Infections of genito-urinary tract in pregnancy
0.636 0.363 0.000
O22 Venous complications in pregnancy
0.636 0.363 0.000
O21 Excessive vomiting in pregnancy
0.636 0.363 0.000
O25 Malnutrition in pregnancy
0.636 0.363 0.000
M11 Other crystal arthropathies
0.636 0.364 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.636 0.364 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.635 0.365 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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