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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs116600709
log Bayes Factor = 13.3425
Chromosome 2   position 111,736,824  (GRCh37) Explore rs116600709 on Ensembl!
Variant rs116600709 is part of Cluster X0148

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.999 0.001 0.000
Z85 Personal history of malignant neoplasm
0.999 0.001 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.998 0.002 0.000
Chapter X Diseases of the respiratory system
0.997 0.003 0.000
Chapter II Neoplasms
0.997 0.003 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.996 0.004 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.992 0.008 0.000
I21 Acute myocardial infarction
0.988 0.012 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.984 0.016 0.000
I21.9 Acute myocardial infarction, unspecified
0.980 0.020 0.000
Z85.4 Personal history of malignant neoplasm of genital organs
0.979 0.021 0.000
J40-J47 Chronic lower respiratory diseases
0.976 0.024 0.000
Z95.0 Presence of cardiac pacemaker
0.976 0.024 0.000
I25 Chronic ischaemic heart disease
0.967 0.033 0.000
Chapter VII Diseases of the eye and adnexa
0.965 0.035 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.964 0.036 0.000
Chapter XX External causes of morbidity and mortality
0.961 0.039 0.000
I25.2 Old myocardial infarction
0.959 0.041 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.958 0.042 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.956 0.044 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.954 0.046 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.951 0.049 0.000
J09-J18 Influenza and pneumonia
0.949 0.051 0.000
I77 Other disorders of arteries and arterioles
0.942 0.058 0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems
0.942 0.058 0.000
I20 Angina pectoris
0.933 0.067 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.932 0.068 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.931 0.069 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.927 0.073 0.000
I71 Aortic aneurysm and dissection
0.925 0.075 0.000
Z94 Transplanted organ and tissue status
0.923 0.077 0.000
T81 Complications of procedures, not elsewhere classified
0.921 0.079 0.000
O80-O84 Delivery
0.917 0.083 0.000
C34 Malignant neoplasm of bronchus and lung
0.917 0.083 0.000
J95-J99 Other diseases of the respiratory system
0.914 0.086 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.912 0.088 0.000
S40-S49 Injuries to the shoulder and upper arm
0.912 0.088 0.000
J44 Other chronic obstructive pulmonary disease
0.911 0.089 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.910 0.090 0.000
Z85.5 Personal history of malignant neoplasm of urinary tract
0.906 0.094 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.905 0.095 0.000
I22 Subsequent myocardial infarction
0.902 0.098 0.000
I20.0 Unstable angina
0.899 0.101 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.897 0.103 0.000
Z95.2 Presence of prosthetic heart valve
0.897 0.103 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.896 0.104 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.895 0.105 0.000
D00-D09 In situ neoplasms
0.894 0.106 0.000
T86 Failure and rejection of transplanted organs and tissues
0.892 0.108 0.000
Z45 Adjustment and management of implanted device
0.890 0.110 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.887 0.113 0.000
Z83 Family history of other specific disorders
0.887 0.113 0.000
S20-S29 Injuries to the thorax
0.885 0.115 0.000
C51-C58 Malignant neoplasms of female genital organs
0.883 0.117 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.883 0.117 0.000
W00-W19 Falls
0.882 0.118 0.000
Z92 Personal history of medical treatment
0.879 0.121 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.879 0.121 0.000
S70-S79 Injuries to the hip and thigh
0.878 0.122 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.878 0.122 0.000
O80 Single spontaneous delivery
0.878 0.122 0.000
Chapter XXII Codes for special purposes
0.874 0.126 0.000
J43 Emphysema
0.873 0.127 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.870 0.130 0.000
O00-O08 Pregnancy with abortive outcome
0.867 0.133 0.000
I74 Arterial embolism and thrombosis
0.867 0.133 0.000
Q60-Q64 Congenital malformations of the urinary system
0.866 0.133 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.863 0.137 0.000
J42 Unspecified chronic bronchitis
0.861 0.139 0.000
R05 Cough
0.857 0.143 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.855 0.145 0.000
J98 Other respiratory disorders
0.854 0.146 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.854 0.146 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.853 0.147 0.000
J18 Pneumonia, organism unspecified
0.850 0.150 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.848 0.152 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.847 0.153 0.000
Z43 Attention to artificial openings
0.845 0.155 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.844 0.156 0.000
C34.1 Upper lobe, bronchus or lung
0.843 0.157 0.000
Z95.1 Presence of aortocoronary bypass graft
0.843 0.157 0.000
Chapter VIII Diseases of the ear and mastoid process
0.842 0.158 0.000
H55-H59 Other disorders of eye and adnexa
0.841 0.159 0.000
I77.1 Stricture of artery
0.839 0.160 0.000
R90.8 Other abnormal findings on diagnostic imaging of central nervous system
0.835 0.165 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.834 0.166 0.000
Z94.8 Other transplanted organ and tissue status
0.830 0.170 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.829 0.171 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.823 0.177 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.823 0.177 0.000
Z92.3 Personal history of irradiation
0.822 0.178 0.000
R00 Abnormalities of heart beat
0.822 0.178 0.000
T79-T79 Certain early complications of trauma
0.821 0.179 0.000
J90-J94 Other diseases of pleura
0.819 0.181 0.000
D05 Carcinoma in situ of breast
0.819 0.181 0.000
O80.0 Spontaneous vertex delivery
0.818 0.182 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.815 0.185 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.811 0.189 0.000
Q61 Cystic kidney disease
0.810 0.190 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.810 0.190 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.808 0.192 0.000
Z45.2 Adjustment and management of vascular access device
0.807 0.193 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.804 0.196 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.804 0.196 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.803 0.197 0.000
Z95.3 Presence of xenogenic heart valve
0.802 0.197 0.000
S00-S09 Injuries to the head
0.801 0.199 0.000
J43.9 Emphysema, unspecified
0.800 0.200 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.799 0.201 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.799 0.201 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.799 0.201 0.000
I95 Hypotension
0.798 0.202 0.000
J11 Influenza, virus not identified
0.798 0.202 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.796 0.203 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.794 0.206 0.000
Z95.4 Presence of other heart-valve replacement
0.792 0.208 0.000
H90-H95 Other disorders of ear
0.791 0.209 0.000
C81 Hodgkin's disease
0.790 0.210 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.789 0.211 0.000
H52 Disorders of refraction and accommodation
0.788 0.212 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.787 0.213 0.000
C54 Malignant neoplasm of corpus uteri
0.786 0.214 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.786 0.214 0.000
R00.1 Bradycardia, unspecified
0.786 0.214 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.783 0.216 0.000
S29 Other and unspecified injuries of thorax
0.782 0.218 0.000
C91 Lymphoid leukaemia
0.779 0.221 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.778 0.222 0.000
I77.8 Other specified disorders of arteries and arterioles
0.778 0.222 0.000
C83.0 Small cell (diffuse)
0.777 0.223 0.000
J98.4 Other disorders of lung
0.777 0.223 0.000
C83.1 Small cleaved cell (diffuse)
0.775 0.225 0.000
I78 Diseases of capillaries
0.775 0.225 0.000
W19 Unspecified fall
0.775 0.225 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.774 0.226 0.000
C34.3 Lower lobe, bronchus or lung
0.774 0.226 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.773 0.227 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.772 0.227 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.772 0.228 0.000
C34.9 Bronchus or lung, unspecified
0.771 0.229 0.000
Z83.5 Family history of eye and ear disorders
0.771 0.229 0.000
J18.9 Pneumonia, unspecified
0.770 0.230 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.770 0.230 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.768 0.232 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.767 0.233 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.767 0.233 0.000
T86.8 Failure and rejection of other transplanted organs and tissues
0.766 0.234 0.000
Z22 Carrier of infectious disease
0.765 0.235 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.765 0.235 0.000
I74.5 Embolism and thrombosis of iliac artery
0.764 0.236 0.000
H43-H45 Disorders of vitreous body and globe
0.764 0.236 0.000
O80.9 Single spontaneous delivery, unspecified
0.762 0.238 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.761 0.239 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.760 0.240 0.000
R03.1 Nonspecific low blood-pressure reading
0.759 0.241 0.000
I77.6 Arteritis, unspecified
0.757 0.243 0.000
Z51 Other medical care
0.756 0.244 0.000
J40 Bronchitis, not specified as acute or chronic
0.755 0.245 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.754 0.246 0.000
I24 Other acute ischaemic heart diseases
0.753 0.247 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.752 0.248 0.000
O03 Spontaneous abortion
0.751 0.249 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.750 0.250 0.000
S90-S99 Injuries to the ankle and foot
0.749 0.251 0.000
H57 Other disorders of eye and adnexa
0.748 0.252 0.000
I05-I09 Chronic rheumatic heart diseases
0.748 0.252 0.000
I95.2 Hypotension due to drugs
0.747 0.252 0.000
Chapter I Certain infectious and parasitic diseases
0.746 0.254 0.000
I20.8 Other forms of angina pectoris
0.746 0.254 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.746 0.254 0.000
T86.1 Kidney transplant failure and rejection
0.744 0.256 0.000
Z94.0 Kidney transplant status
0.744 0.256 0.000
R94 Abnormal results of function studies
0.744 0.256 0.000
Z83.4 Family history of other endocrine, nutritional and metabolic diseases
0.743 0.257 0.000
O85-O92 Complications predominantly related to the puerperium
0.743 0.257 0.000
I99 Other and unspecified disorders of circulatory system
0.742 0.258 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.740 0.260 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.738 0.262 0.000
Y52 Agents primarily affecting the cardiovascular system
0.736 0.264 0.000
H92 Otalgia and effusion of ear
0.736 0.264 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.735 0.265 0.000
S09 Other and unspecified injuries of head
0.735 0.265 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.734 0.266 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.734 0.266 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.734 0.266 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.734 0.266 0.000
T81.9 Unspecified complication of procedure
0.733 0.267 0.000
I20.1 Angina pectoris with documented spasm
0.732 0.268 0.000
S70 Superficial injury of hip and thigh
0.730 0.270 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.728 0.271 0.000
R00.0 Tachycardia, unspecified
0.728 0.272 0.000
I72 Other aneurysm
0.728 0.272 0.000
Q61.3 Polycystic kidney, unspecified
0.728 0.272 0.000
C83.3 Large cell (diffuse)
0.727 0.272 0.000
J46 Status asthmaticus
0.726 0.274 0.000
C32 Malignant neoplasm of larynx
0.726 0.274 0.000
H10-H13 Disorders of conjunctiva
0.726 0.274 0.000
C50-C50 Malignant neoplasm of breast
0.725 0.275 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.724 0.276 0.000
J93 Pneumothorax
0.724 0.276 0.000
O47 False labour
0.724 0.276 0.000
X60-X84 Intentional self-harm
0.722 0.278 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.721 0.279 0.000
Z29 Need for other prophylactic measures
0.721 0.279 0.000
J20-J22 Other acute lower respiratory infections
0.721 0.279 0.000
W13 Fall from, out of or through building or structure
0.720 0.280 0.000
Z81 Family history of mental and behavioural disorders
0.719 0.281 0.000
D05.1 Intraductal carcinoma in situ
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C54.1 Endometrium
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I70 Atherosclerosis
0.717 0.283 0.000
S79 Other and unspecified injuries of hip and thigh
0.717 0.283 0.000
T33-T35 Frostbite
0.716 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.283 0.000
S10-S19 Injuries to the neck
0.716 0.283 0.000
Z84 Family history of other conditions
0.716 0.283 0.000
Z85.0 Personal history of malignant neoplasm of digestive organs
0.716 0.284 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.716 0.284 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.716 0.284 0.000
T66-T78 Other and unspecified effects of external causes
0.716 0.284 0.000
S27 Injury of other and unspecified intrathoracic organs
0.715 0.285 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.715 0.285 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.715 0.285 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.715 0.285 0.000
H25-H28 Disorders of lens
0.715 0.285 0.000
H04 Disorders of lachrymal system
0.714 0.286 0.000
T87 Complications peculiar to reattachment and amputation
0.714 0.286 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.714 0.286 0.000
R87 Abnormal findings in specimens from female genital organs
0.713 0.287 0.000
J10 Influenza due to identified influenza virus
0.713 0.287 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.713 0.287 0.000
Z89 Acquired absence of limb
0.712 0.288 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.711 0.289 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.711 0.289 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.711 0.289 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.711 0.289 0.000
Z72 Problems related to lifestyle
0.711 0.289 0.000
O00 Ectopic pregnancy
0.710 0.290 0.000
R30-R39 Symptoms and signs involving the urinary system
0.710 0.290 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.710 0.290 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.709 0.291 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.709 0.291 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.708 0.291 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.708 0.291 0.000
O21 Excessive vomiting in pregnancy
0.708 0.292 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.708 0.292 0.000
S29.9 Unspecified injury of thorax
0.707 0.293 0.000
Z43.5 Attention to cyctostomy
0.706 0.294 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.705 0.295 0.000
H20 Iridocyclitis
0.703 0.297 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.702 0.298 0.000
Z94.7 Corneal transplant status
0.701 0.299 0.000
Q00-Q07 Congenital malformations of the nervous system
0.701 0.299 0.000
H49 Paralytic strabismus
0.701 0.299 0.000
O81 Single delivery by forceps and vacuum extractor
0.701 0.299 0.000
Q80-Q89 Other congenital malformations
0.700 0.300 0.000
Z92.0 Personal history of contraception
0.700 0.300 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.700 0.300 0.000
J41 Simple and mucopurulent chronic bronchitis
0.700 0.300 0.000
I27 Other pulmonary heart diseases
0.700 0.300 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.700 0.300 0.000
Y40 Systemic antibiotics
0.699 0.301 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.698 0.302 0.000
T82.1 Mechanical complication of cardiac electronic device
0.698 0.302 0.000
J30-J39 Other diseases of upper respiratory tract
0.698 0.302 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.698 0.302 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.697 0.303 0.000
Z60 Problems related to social environment
0.696 0.304 0.000
H00 Hordeolum and chalazion
0.695 0.305 0.000
W19.2 School, other institution and public administrative area
0.694 0.306 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.694 0.306 0.000
I25.6 Silent myocardial ischaemia
0.693 0.306 0.000
I25.4 Coronary artery aneurysm
0.693 0.306 0.000
I25.3 Aneurysm of heart
0.693 0.306 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.693 0.307 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.692 0.308 0.000
S41 Open wound of shoulder and upper arm
0.692 0.308 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.691 0.309 0.000
C95 Leukaemia of unspecified cell type
0.691 0.309 0.000
C94 Other leukaemias of specified cell type
0.691 0.309 0.000
C93 Monocytic leukaemia
0.691 0.309 0.000
C88 Malignant immunoproliferative diseases
0.691 0.309 0.000
C86 Other specified types of T/NK-cell lymphoma
0.691 0.309 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.691 0.309 0.000
J14 Pneumonia due to Haemophilus influenzae
0.690 0.310 0.000
J11.1 Influenza with other respiratory manifestations, virus not identified
0.690 0.310 0.000
O02 Other abnormal products of conception
0.689 0.311 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.689 0.311 0.000
Y35-Y36 Legal intervention and operations of war
0.689 0.311 0.000
Y10-Y34 Event of undetermined intent
0.689 0.311 0.000
Y00-Y09 Assault
0.689 0.311 0.000
X85-X99 Assault
0.689 0.311 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.689 0.311 0.000
X50-X57 Overexertion, travel and privation
0.689 0.311 0.000
X30-X39 Exposure to forces of nature
0.689 0.311 0.000
X20-X29 Contact with venomous animals and plants
0.689 0.311 0.000
X10-X19 Contact with heat and hot substances
0.689 0.311 0.000
X00-X09 Exposure to smoke, fire and flames
0.689 0.311 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.689 0.311 0.000
W75-W84 Other accidental threats to breathing
0.689 0.311 0.000
W65-W74 Accidental drowning and submersion
0.689 0.311 0.000
W50-W64 Exposure to animate mechanical forces
0.689 0.311 0.000
V98-V99 Other and unspecified transport accidents
0.689 0.311 0.000
V95-V97 Air and space transport accidents
0.689 0.311 0.000
V90-V94 Water transport accidents
0.689 0.311 0.000
V80-V89 Other land transport accidents
0.689 0.311 0.000
V70-V79 Bus occupant injured in transport accident
0.689 0.311 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.689 0.311 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.689 0.311 0.000
V40-V49 Car occupant injured in transport accident
0.689 0.311 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.689 0.311 0.000
V01-V09 Pedestrian injured in transport accident
0.689 0.311 0.000
R31 Unspecified haematuria
0.689 0.311 0.000
S20 Superficial injury of thorax
0.688 0.312 0.000
J98.1 Pulmonary collapse
0.688 0.312 0.000
Z43.3 Attention to colostomy
0.688 0.312 0.000
S09.9 Unspecified injury of head
0.687 0.313 0.000
Z40 Prophylactic surgery
0.687 0.313 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.686 0.314 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.686 0.314 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.686 0.314 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.684 0.316 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.684 0.316 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.684 0.316 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.684 0.316 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.684 0.316 0.000
C31 Malignant neoplasm of accessory sinuses
0.684 0.316 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.684 0.316 0.000
C37 Malignant neoplasm of thymus
0.684 0.316 0.000
C33 Malignant neoplasm of trachea
0.684 0.316 0.000
O30 Multiple gestation
0.683 0.317 0.000
Y44 Agents primarily affecting blood constituents
0.683 0.317 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.682 0.318 0.000
H18 Other disorders of cornea
0.681 0.319 0.000
J17 Pneumonia in diseases classified elsewhere
0.680 0.319 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.680 0.319 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.680 0.319 0.000
J12 Viral pneumonia, not elsewhere classified
0.680 0.319 0.000
J09 Influenza due to certain identified influenza virus
0.680 0.319 0.000
R90.0 Intracranial space-occupying lesion
0.680 0.320 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.680 0.320 0.000
D04 Carcinoma in situ of skin
0.679 0.321 0.000
O44 Placenta praevia
0.678 0.321 0.000
I25.5 Ischaemic cardiomyopathy
0.678 0.322 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.678 0.322 0.000
Z22.3 Carrier of other specified bacterial diseases
0.678 0.322 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.677 0.322 0.000
Z83.3 Family history of diabetes mellitus
0.677 0.323 0.000
Z50 Care involving use of rehabilitation procedures
0.676 0.324 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.676 0.324 0.000
I77.5 Necrosis of artery
0.676 0.324 0.000
I77.4 Coeliac artery compression syndrome
0.676 0.324 0.000
I77.3 Arterial fibromuscular dysplasia
0.676 0.324 0.000
I77.2 Rupture of artery
0.676 0.324 0.000
I77.0 Arteriovenous fistula, acquired
0.676 0.324 0.000
C73 Malignant neoplasm of thyroid gland
0.676 0.324 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.675 0.325 0.000
S50-S59 Injuries to the elbow and forearm
0.675 0.325 0.000
H52.1 Myopia
0.674 0.326 0.000
W20-W49 Exposure to inanimate mechanical forces
0.673 0.327 0.000
Y57 Other and unspecified drugs and medicaments
0.673 0.327 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.673 0.327 0.000
V10-V19 Pedal cyclist injured in transport accident
0.673 0.327 0.000
W06 Fall involving bed
0.672 0.328 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.671 0.329 0.000
S46.0 Injury of tendon of the rotator cuff of shoulder
0.671 0.329 0.000
Z51.3 Blood transfusion without reported diagnosis
0.669 0.331 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.669 0.331 0.000
Z48 Other surgical follow-up care
0.669 0.331 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.668 0.332 0.000
Q35-Q37 Cleft lip and cleft palate
0.668 0.332 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.668 0.332 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.668 0.332 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.667 0.333 0.000
H92.0 Otalgia
0.667 0.333 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.667 0.333 0.000
R06 Abnormalities of breathing
0.667 0.333 0.000
M20-M25 Other joint disorders
0.667 0.333 0.000
Z72.0 Tobacco use
0.667 0.333 0.000
D06 Carcinoma in situ of cervix uteri
0.667 0.333 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.667 0.333 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.666 0.334 0.000
C81.9 Hodgkin's disease, unspecified
0.666 0.334 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.666 0.334 0.000
M25 Other joint disorders, not elsewhere classified
0.666 0.334 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.665 0.335 0.000
Z43.2 Attention to ileostomy
0.665 0.335 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.664 0.336 0.000
R94.3 Abnormal results of cardiovascular function studies
0.664 0.336 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.663 0.337 0.000
R25 Abnormal involuntary movements
0.663 0.337 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.663 0.337 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.663 0.337 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.663 0.337 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.663 0.337 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.663 0.337 0.000
H52.0 Hypermetropia
0.663 0.337 0.000
O28 Abnormal findings on antenatal screening of mother
0.663 0.337 0.000
Z94.9 Transplanted organ and tissue status, unspecified
0.662 0.338 0.000
Z94.6 Bone transplant status
0.662 0.338 0.000
Z94.5 Skin transplant status
0.662 0.338 0.000
Z94.4 Liver transplant status
0.662 0.338 0.000
Z94.3 Heart and lungs transplant status
0.662 0.338 0.000
Z94.2 Lung transplant status
0.662 0.338 0.000
Z94.1 Heart transplant status
0.662 0.338 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.661 0.339 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.661 0.339 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.661 0.339 0.000
J47 Bronchiectasis
0.660 0.340 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.659 0.341 0.000
W08 Fall involving other furniture
0.659 0.341 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.659 0.341 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.659 0.341 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.658 0.341 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.658 0.342 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.658 0.342 0.000
O84 Multiple delivery
0.658 0.342 0.000
O83 Other assisted single delivery
0.658 0.342 0.000
C34.8 Overlapping lesion of bronchus and lung
0.658 0.342 0.000
C34.2 Middle lobe, bronchus or lung
0.658 0.342 0.000
D09 Carcinoma in situ of other and unspecified sites
0.658 0.342 0.000
I97.1 Other functional disturbances following cardiac surgery
0.656 0.343 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.656 0.344 0.000
J96 Respiratory failure, not elsewhere classified
0.656 0.344 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.655 0.345 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.654 0.346 0.000
C64-C68 Malignant neoplasms of urinary tract
0.654 0.346 0.000
Z43.6 Attention to other artificial openings of urinary tract
0.654 0.346 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.654 0.346 0.000
Z44 Fitting and adjustment of external prosthetic device
0.654 0.346 0.000
S48 Traumatic amputation of shoulder and upper arm
0.654 0.346 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.654 0.346 0.000
S44 Injury of nerves at shoulder and upper arm level
0.654 0.346 0.000
S47 Crushing injury of shoulder and upper arm
0.654 0.346 0.000
S72 Fracture of femur
0.653 0.346 0.000
S43.0 Dislocation of shoulder joint
0.653 0.347 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.653 0.347 0.000
C83.7 Burkitt's tumour
0.653 0.347 0.000
C83.6 Undifferentiated (diffuse)
0.653 0.347 0.000
C83.5 Lymphoblastic (diffuse)
0.653 0.347 0.000
C83.4 Immunoblastic (diffuse)
0.653 0.347 0.000
C83.2 Mixed small and large cell (diffuse)
0.653 0.347 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.652 0.348 0.000
Q61.0 Congenital single renal cyst
0.651 0.349 0.000
I97.2 Postmastectomy lymphoedema syndrome
0.650 0.350 0.000
C51 Malignant neoplasm of vulva
0.650 0.350 0.000
O45 Premature separation of placenta [abruptio placentae]
0.649 0.351 0.000
O43 Placental disorders
0.649 0.351 0.000
O41 Other disorders of amniotic fluid and membranes
0.649 0.351 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.649 0.351 0.000
O33 Maternal care for known or suspected disproportion
0.649 0.351 0.000
O31 Complications specific to multiple gestation
0.649 0.351 0.000
O40 Polyhydramnios
0.649 0.351 0.000
Q61.2 Polycystic kidney, adult type
0.648 0.351 0.000
J93.9 Pneumothorax, unspecified
0.648 0.352 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.648 0.352 0.000
I22.8 Subsequent myocardial infarction of other sites
0.646 0.353 0.000
S42 Fracture of shoulder and upper arm
0.645 0.355 0.000
H50 Other strabismus
0.644 0.356 0.000
R87.6 Abnormal cytological findings
0.644 0.356 0.000
D05.0 Lobular carcinoma in situ
0.643 0.357 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.643 0.357 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.643 0.357 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.643 0.357 0.000
J18.1 Lobar pneumonia, unspecified
0.642 0.358 0.000
Q50-Q56 Congenital malformations of genital organs
0.642 0.358 0.000
J90 Pleural effusion, not elsewhere classified
0.642 0.358 0.000
I71.0 Dissection of aorta [any part]
0.642 0.358 0.000
Y59 Other and unspecified vaccines and biological substances
0.641 0.359 0.000
Y58 Bacterial vaccines
0.641 0.359 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.641 0.359 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.641 0.359 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.641 0.359 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.641 0.359 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.641 0.359 0.000
Y48 Anaesthetics and therapeutic gases
0.641 0.359 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.641 0.359 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.641 0.359 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.641 0.359 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.641 0.359 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.641 0.359 0.000
C92 Myeloid leukaemia
0.641 0.359 0.000
Z43.1 Attention to gastrostomy
0.640 0.359 0.000
T86.9 Failure and rejection of unspecified transplanted organ and tissue
0.640 0.360 0.000
T86.4 Liver transplant failure and rejection
0.640 0.360 0.000
T86.3 Heart-lung transplant failure and rejection
0.640 0.360 0.000
T86.2 Heart transplant failure and rejection
0.640 0.360 0.000
T86.0 Bone-marrow transplant rejection
0.640 0.360 0.000
O23 Infections of genito-urinary tract in pregnancy
0.639 0.360 0.000
Z45.9 Adjustment and management of unspecified implanted device
0.638 0.362 0.000
Z45.3 Adjustment and management of implanted hearing device
0.638 0.362 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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